33results about "Ball valves" patented technology

Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.

Systems and methods for controlling blood pressure by controlling atrial pressure and atrial stretch are disclosed. In some embodiments, a stimulation circuit may be configured to deliver a stimulation pulse to at least one cardiac chamber of a heart of a patient, and at least one controller may be configured to execute delivery of one or more stimulation patterns of stimulation pulses to the at least one cardiac chamber, wherein at least one of the stimulation pulses stimulates the heart such that an atrial pressure resulting from atrial contraction of an atrium overlaps in time a passive pressure build-up of the atrium, such that an atrial pressure of the atrium resulting from the stimulation is a combination of the atrial pressure resulting from atrial contraction and the passive pressure build-up and is higher than an atrial pressure of the atrium would be without the stimulation, and such that the blood pressure of the patient is reduced.

The invention relates to a loopable medical device and a medical system comprising the loopable medical device. The medical device capable of forming the ring comprises a main body part, a first connecting part and a second connecting part. The main body part is configured to be capable of being converted from a straight structure to a bent structure and comprises a first end and a second end which are oppositely arranged in the axial direction. The first connecting part is connected with the first end of the main body part; the second connecting part is connected with the second end of the main body part; the first connecting part is provided with a first structure which laterally protrudes out of the first end of the main body part and faces the second connecting part, and when the main body part is converted from the straight structure to the bent structure, the second connecting part and the first connecting part facing the second connecting part can be connected and locked with each other; thus, the first connecting part, the second connecting part and the main body part in the bent structure form a ring together. The ring forming operation of the medical device capable of forming the ring is simple and convenient.

A system and method for reducing ventricular filling volume is disclosed. A stimulation circuit is used to stimulate a patient's heart to reduce ventricular filling or blood pressure. Stimulating the heart to a certain degree to reduce blood pressure may cause the cardiovascular system to eventually adapt to the stimulation and return to a higher blood pressure. To reduce or prevent the heart's adaptive response, the stimulation pattern may be configured inconsistently, and the stimulation circuit may be used to stimulate the patient's heart to cause at least some of the atrial contractions with the atrioventricular valves closed. Such atrial contractions allow less blood to enter the corresponding ventricle than when the atrioventricular valves are open throughout the entire atrial contraction.

The invention relates to a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.

A medical implant for managing blood flow through a blood vessel comprises a plug, a mounting ring, and one or more arms interconnecting the plug and the mounting ring, wherein the one or more arms are configured to allow movement of the plug relative to the mounting ring.

The invention relates to an access and occluder device, and in particular a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within a transcatheter heart valve replacement, and in particular, an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrrally to the mitral valve, the valve having a height of about 5-60mm and a diameter of about 25-80mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

A medical implant for managing blood flow through a blood vessel comprises a stent body forming a proximal portion and a tapered distal end, the tapered distal end being angled relative to the proximal portion to face a direction of blood flow and limit blood flow into an inner lumen of the stent body, and the tapered distal end having a flexible structure to allow the tapered distal end to bend and straighten in response to blood flow, and a covering extending along the stent body.

A balloon-expandable valve device for transapical mitral valve replacement according to the present invention includes: a soft outer frame and a rigid inner frame. An outer layer of film is wrapped around the outer side surface of the soft outer frame. The distal end of the outer layer of film has a double-layer film. The distal end of the soft outer frame is inserted into the double-layer film and a certain axial distance is reserved between the distal end of the soft outer frame and the distal end of the double-layer film to form a margin space for the elongation of the soft outer frame. The proximal section of the inner layer of film is wrapped around the inner side surface of the rigid inner frame, and the distal section of the inner layer of film extends from the proximal section of the inner layer of film to the middle section of the soft outer frame and is wrapped around the middle section of the inner side surface of the soft outer frame. In the present invention, the inner film of the outer frame is wrapped around the inner side surface of the soft outer frame, and the distal end does not extend to the distal end of the inner side of the soft outer frame, that is, the distal end of the inner film of the outer frame is not covered by the inner side surface of the outer layer of film folded to the inner side of the soft outer frame, thereby removing the limitation on the axial length of the soft outer frame during the compression and elongation process.

The invention relates to a tricuspid regurgitation control device for an orthogonal transcatheter heart valve prosthesis. The invention also relates to access and occluder devices, in particular heart valve regurgitation drums and optionally closure discs and / or tubular stents, for managing and providing intentional regurgitation levels within transcatheter heart valve substitutes and in particular orthogonally delivered transcatheter prosthetic heart valves, an orthogonal delivery transcatheter prosthetic heart valve has a first inner flow control member / valve, a second inner reflux control member, and an outer annular support frame with a compressible wire unit that facilitates flat folding along the z-axis and compression of the valve vertically along the y-axis or orthogonal to the central axis of the flow control member, the present invention relates to a valvular delivery and deployment system, in particular to a valvular delivery and deployment system, which allows delivery and deployment of very large diameter valves from the inferior or superior vena cava to the tricuspid valve or trans-atrial delivery and deployment to the mitral valve, the valves having a height of about 5-60 mm and a diameter of about 25-80 mm, without extra-large diameter catheters and without delivery and deployment from catheters at acute access angles.

The invention relates to an access and occluder device, and in particular a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within a transcatheter heart valve replacement, and in particular, an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrrally to the mitral valve, the valve having a height of about 5-60mm and a diameter of about 25-80mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The present invention relates to a mechanical artificial heart valve (10), comprising: an annular support (12) having an inner peripheral wall (14) centered on a longitudinal axis (X) and defining an internal passage; and at least two active leaflets, preferably three active leaflets (40) arranged in such a manner that each leaflet can achieve a rotational movement around a rotation axis perpendicular to the longitudinal axis (X), so that the valve (10) can be transformed from a closed configuration to an open configuration, and vice versa. Each leaflet (40) comprises a leading edge (42) designed to abut against a portion of the inner peripheral wall (14) of the annular support (12) when the valve is in the closed configuration, an inner surface (46b) extending from the leading edge (42), and an outer surface (46a) opposite to the inner surface (46b) and extending from the leading edge (42). The annular support member (12) comprises: at least one lower support member (16a, 16b) for each leaflet on the inner peripheral wall (14), the lower support member (16a, 16b) being located between two of the extensions (30) and being designed to contact against the corresponding leaflet when the valve (10) is in a closed configuration; and two upper support members (20a, 20b). The two upper support members (20a, 20b) each comprise a distal end (21). Each distal end (21) is designed to contact against a support area of ​​an outer surface (46a) of a leaflet (40). The center of the support area (54) is set back from the leading edge (42) of the leaflet (40) by a distance (d2), the distance (d2) being greater than the thickness (t2) of the leaflet at the center of the support area.

The present invention relates to an access and occluder device, in particular a heart valve regurgitation drum and optional occlusion disc and / or annular stent for managing and providing a level of intentional regurgitation in a transcatheter heart valve replacement, in particular an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a first inner regurgitation control component and an outer annular support frame having compressible wire cells.SOLUTION: The compressible wire cells facilitate folding flat along the z-axis and compressing the valves vertically along the y-axis or orthogonal to the central axes of the flow control components, enabling the delivery and placement of very large diameter valves from the inferior or superior vena cavae to the tricuspid valves or transatrially to the mitral valves, having heights of about 5 to 60mm and diameters of about 25 to 80mm, without the need for an oversized catheter and without the need for delivery and placement from a catheter with a sharp approach angle.SELECTED DRAWING: Figure 3

The invention belongs to the technical field of medical apparatus and instruments, and particularly relates to a heart valve replacement system which comprises a valve stent, the valve stent is of a single-layer self-expansion structure, and the valve stent comprises a stent body and a skirt structure which are integrally connected from the outflow end to the inflow end; the anchoring support is of a sphere-like structure, and the anchoring support is located on the inner side of the skirt structure and abuts against the skirt structure in a split mode. The valve stent is a single-layer self-expansion stent, the single-layer structure can facilitate pressing, holding and conveying, and the valve stent and the anchoring stent are of a split structure, so that the valve stent and the anchoring stent can be conveyed in a split mode, the pressing and holding diameter is small, conveying and implanting in a transfemoral mode and the like are facilitated, and the valve stent and the anchoring stent are conveyed in a split mode and enter the human body step by step; and a thinner catheter can be adopted to be conveyed and implanted into the human body, so that the expansion of the blood vessel is reduced.

The invention relates to an access and occluder device, and in particular a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within a transcatheter heart valve replacement, and in particular, an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having compressible wire cells that facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrrally to the mitral valve, the valve having a height of about 5-60mm and a diameter of about 25-80mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

A medical implant for managing blood flow through a blood vessel includes a plug, an attachment ring, and one or more arms interconnecting the plug and the attachment ring, the one or more arms configured to allow movement of the plug relative to the attachment ring.

The invention discloses a single-leaf mechanical valve which comprises a mechanical valve ring, a limiting base, a movable valve leaf and a guide rod. A via hole is formed in the middle of the mechanical valve ring; the limiting base is installed at the bottom of the mechanical valve ring, and an open moving area is arranged between the mechanical valve ring and the limiting base; the movable valve leaflet and the guide rod are both located in the movable area, and the movable valve leaflet can move up and down in a reciprocating mode in the track direction of the guide rod, so that the movable valve leaflet can movably open or close the whole channel opening of the through hole, the opening area is relatively increased, and the valve crossing pressure difference is small; through cooperation of the movable valve leaflet and the guide rod, thrombus formation is effectively avoided, and damage is not prone to occurring; even if thrombus is formed, the valve is not prone to being clamped, the risk of valve clamping or dysfunction is avoided, and anticoagulation treatment can be reduced or not needed. According to the mechanical valve, a larger opening area is provided, the performance of the valve is remarkably improved, and the mechanical valve is suitable for more clinical patients, especially small-valve-ring or low-weight patients.

The present invention relates to a cardiac implant and an implantation system including the cardiac implant. The cardiac implant is configured to be advanced along a guidewire having a distal end that is annular or substantially annular, and includes a main body, a first connecting portion, and a second connecting portion. The main body includes a straight structure and a curved structure, and the main body includes a first end and a second end that are axially opposite. The first connecting portion is connected to the first end of the main body. The second connecting portion is connected to the second end of the main body. During advancement, the main body is transformed from a straight structure to a curved structure, and various parts of the main body are capable of transmitting axial force and movement to avoid axial stacking. The second connecting portion and the first connecting portion can be connected and locked to each other, thereby forming a ring together with the main body in the curved structure. The cardiac implant of the present invention can be formed into a ring by simply pushing, and no stacking will occur during the pushing process, which effectively reduces the difficulty of forming a ring for the cardiac implant.

The application belongs to the technical field of medical devices, and particularly relates to a heart valve replacement system, which comprises: a valve support, the valve support is a single-layer self-expanding structure, the valve support comprises a support body and a skirt structure which are integrally connected from an outflow end to an inflow end; and an anchoring support, the anchoring support is a spherical structure, the anchoring support is located on the inner side of the skirt structure and is detachably abutted on the skirt structure. The valve support of the application is a single-layer self-expanding support, the single-layer structure is conducive to compression and delivery, the valve support and the anchoring support are a detachable structure, so that they can be delivered separately, the compression diameter is small, and the delivery and implantation through the femoral artery and the like are facilitated, the two are delivered separately and are sequentially introduced into the human body, a thinner catheter can be used for delivery and implantation into the human body, and the expansion of the blood vessel is reduced.

To provide an access and occluder device, in particular a heart valve regurgitation drum and optional closure disk and / or tubular stent to manage and provide levels of intentional regurgitation within a transcatheter heart valve replacement, and in particular, an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a first inner regurgitation control component, and an outer annular support frame having compressible wire cells.SOLUTION: Compressible wire cells facilitate folding flat along the z-axis and compressing the valve vertically along the y-axis, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrrally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.SELECTED DRAWING: Figure 3

Systems and methods for reducing ventricular filling volume are disclosed.SOLUTION: The stimulation circuit is used to stimulate the patient's heart to reduce ventricular filling volume or blood pressure. When the heart is stimulated to a certain degree to reduce the blood pressure, the cardiovascular system may eventually adapt to the stimulation and return to a higher blood pressure. The stimulation pattern may be inconsistently configured such that an adaptive response of the heart is reduced or prevented, and the stimulation circuitry may be used to stimulate the patient's heart to cause at least a portion of the atrial contraction with the atrioventricular valve closed. Such atrial contraction causes less blood to enter the corresponding ventricle than when the atrioventricular valve is open throughout atrial contraction.SELECTED DRAWING: Figure 9

The invention discloses a valve stent, a valve prosthesis and a valve prosthesis system. The valve stent comprises an outer stent, an inner stent and an outer stent, the inner bracket is at least partially arranged in the outer bracket; the connecting piece is connected between the outer stent and the inner stent and allows one of the outer stent and the inner stent to move within a preset distance relative to the other one of the outer stent and the inner stent after being subjected to external force, so that the interaction time of blood and the valve stent is prolonged. Therefore, mutual influence between the valve leaflet of the outer stent and the valve leaflet of the inner stent can be weakened or isolated, and action time between blood and the inner stent and action time between blood and the outer stent can be prolonged, so that influence of the valve stent on ventricular contractility can be reduced, and closing stability of the valve leaflet is improved. Meanwhile, the impact force of blood flow on the valve stent during cardiac contraction can be reduced, the fatigue resistance of the valve stent can be improved, and the service life of the valve stent can be prolonged.

The present invention relates to a passageway and occluder device for managing and providing intentional regurgitation levels within transcatheter heart valve replacements, and specifically ortho-delivered transcatheter prosthetic heart valves having a first inner flow control component / valve, a second inner regurgitation control component, and an outer annular support frame having a compressible wire unit that facilitates collapsing along the z-axis and compressing the valve vertically along the y-axis or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or transatrially to the mitral valve, with a height of about 5-60 mm and a diameter of about 25-80 mm, without the need for an ultra-large diameter catheter and without the need to be delivered and deployed from the catheter at an acute angle of approach.

The present invention discloses a single-leaflet mechanical valve, comprising a mechanical valve ring, a limiting base, a movable leaflet and a guide rod; a conducting hole is provided in the middle of the mechanical valve ring; the limiting base is mounted to the bottom of the mechanical valve ring, and an open movable area is provided between the mechanical valve ring and the limiting base; the movable leaflet and the guide rod are both located in the movable area, and the movable leaflet can move back and forth up and down along the trajectory direction of the guide rod, so that the movable leaflet can move to open or close the entire channel opening of the conducting hole, so as to achieve a relatively increased opening area and a small transvalvular pressure difference; the present invention effectively avoids thrombosis through the cooperation of the movable leaflet and the guide rod, and is not easy to be damaged; even if thrombosis is formed, it is not easy to cause the valve to get stuck, thus avoiding the risk of valve sticking or dysfunction, and can reduce or eliminate the need for anticoagulation treatment; the mechanical valve provides a larger opening area, significantly improves the performance of the valve, and is suitable for more clinical patients, especially patients with small valve rings or low body weight.

Methods and devices for reducing ventricle filling volume are disclosed. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to reduce ventricle filling volume or even blood pressure. When the heart is stimulated in a consistent way to reduce blood pressure, the cardiovascular system may over time adapt to the stimulation and revert back to the higher blood pressure. In some embodiments, the stimulation pattern may be configured to be inconsistent such that the adaptation response of the heart is reduced or even prevented. In some embodiments, an electrical stimulator may be used to stimulate a patient's heart to cause at least a portion of an atrial contraction to occur while the atrioventricular valve is closed. Such an atrial contraction may deposit less blood into the corresponding ventricle than when the atrioventricular valve is opened throughout an atrial contraction.

A system for reducing regurgitation includes a catheter and a coaptation member disposed along a distal end portion of the catheter, wherein the coaption member is sized to be advanced through a patient's vasculature in a compressed configuration and wherein the coaptation member is expandable for deployment between leaflets of a native tricuspid valve. The coaptation member includes a frame covered with one or more panels of bioprosthetic tissue or flexible polymer to form a three-sided shape having three convex sides separated by rounded corners. An anchor is coupled to a proximal end portion of the catheter and is shaped for attachment to a vessel wall. After deployment, the anchor secures the position of the coaptation member relative to the native tricuspid valve.

The invention relates to a cardiac implant and an implant system comprising the same. A cardiac implant configured to advance along a guidewire having an annular or substantially annular distal end includes a body portion, a first connection portion, and a second connection portion. The main body portion includes a straight configuration and a curved configuration, and the main body portion includes a first end and a second end opposite in an axial direction. The first connecting part is connected with the first end of the main body part; the second connecting part is connected with the second end of the main body part; in the propelling process, the main body part is converted into a bent structure from a straight structure, all parts of the main body part can transmit axial force and movement to avoid axial stacking, and the second connecting part and the first connecting part can be connected and locked with each other so as to form a ring together with the main body part in the bent structure. The heart implant can form a ring only through simple and convenient pushing, stacking cannot be generated in the pushing process, and the ring forming difficulty of the heart implant is effectively reduced.

The invention discloses a valve stent and a valve prosthesis, the valve stent comprises: an outer stent having a first connecting end; the inner stent is arranged in the outer stent, the inner stent is provided with a second connecting end, the second connecting end is located on the inner side of the first connecting end, and in the axial direction of the valve stent, a distance difference exists between the second connecting end and the first connecting end; the connecting frame is obliquely connected between the first connecting end and the second connecting end, so that stress between the inner stent and the outer stent is uneven, and the connecting frame is at least used for weakening radial force generated when the inner stent and the outer stent are extruded by the valve ring and decomposing axial force generated by blood pressure impact. Therefore, the impact of blood flow can be reduced, the inner stent can be prevented from axially jumping relative to the outer stent, the received radial force can be dispersed, and the pressure received by the inner stent in the radial direction is reduced, so that the relative stability of the shape and the size of the inner stent can be kept, and the occurrence of perivalvular leakage can be avoided.

The present invention relates to a medical device that can be looped and a medical system including the medical device that can be looped. The medical device that can be looped includes a main body, a first connecting part, and a second connecting part. The main body is configured to be able to transform from a straight structure to a curved structure and includes a first end and a second end arranged opposite to each other along the axial direction. The first connecting part is connected to the first end of the main body. The second connecting part is connected to the second end of the main body. The first connecting part has a first structure that protrudes laterally from the first end of the main body and faces the second connecting part, and when the main body transforms from a straight structure to a curved structure, the second connecting part can be connected to the first connecting part facing the second connecting part and locked with each other, so that the first connecting part, the second connecting part and the main body in the curved structure form a loop together. The looping operation of the medical device that can be looped is relatively simple.