482 results about "Left ventricle wall" patented technology

Interatrial shunts are described herein that are designed to benefit both the left side of the heart and the right side of the heart. The interatrial shunt is anchored in the atrial septum to permit blood to flow between atrial heart chambers across the atrial septum. In accordance with some aspects, the lumen of the shunt has an effective orifice area selected to permit blood flow across the atrial septum to unload the patient's left ventricle with beneficial effects on the patient's right ventricle. The shunts are structured to be suitably anchored at the atrial septum for long-term implantation. Further, the shunts preferably have insignificant late lumen loss. The interatrial shunts are expected to treat pathologies such as heart failure and pulmonary hypertension.

Apparatus and methods are described including a ventricular assist device that includes a tube configured to traverse a subject's aortic valve. The tube defines a generally-cylindrical central portion, and a proximal conical portion that narrows from a proximal end of the central portion to a proximal end of the tube. The tube defines one or more blood inlet openings in a vicinity of a distal end of the tube, and one or more blood outlet openings that extend axially from the central portion of the tube at least partially into the proximal conical portion of the tube. A blood pump pumps blood into the tube from the subject's left ventricle through the one or more blood inlet openings, and from the tube into the aorta through the one or more blood outlet openings. Other applications are also described.

Various systems, devices, and methods are disclosed herein for treating acute myocardial infarction (AMI) patients using a heart pump controlled in a manner that maximizes mechanical unloading of the left ventricle in the presence of cardiovascular instability and minimizes myocardial oxygen consumption (MVO2) and consequentially infarct size to prevent the development of subsequent heart failure. In a closed feedback system, the system can include a sensor configured to generate an output used to measure or calculate a left ventricular systolic pressure (LSVP) within the left ventricle of a heart and a controller coupled to a heart pump. The controller can be configured to measure or calculate the LVSP based on the output of the sensor and to control an operation of the heart pump to maximize mechanical unloading of the left ventricle based on the measured or calculated LVSP.

A device comprises an implantable blood pump receivable in a sheath for percutaneous delivery. The implantable blood pump comprises a collapsible impeller mounted in a collapsible impeller cage, and a drive device mounted in a housing. The housing is in connection between a first end of a catheter and the collapsible impeller cage. The drive device is adapted for rotating the collapsible impeller. A retractable support structure is adapted to extend from the catheter. The extended retractable support structure is adapted to engage with the wall of the aorta for allowing the implantable blood pump to be secured in the left ventricle. The collapsible impeller cage comprises an inlet and an outlet. The inlet is adapted to receive blood from the left ventricle. The outlet directs blood in the direction of the atrioventricular valve.

Apparatus and methods are described including delivering a left-ventricular assist device to a subject's aorta. The device including a distal-tip element that defines a straight proximal portion, and a curved distal portion, the curved distal portion defining first and second curves with an elongated straight portion between the first and second curves. The distal-tip element is centered with respect to the aortic valve using the curved distal portion of the distal-tip element, to thereby guide the device through the subject's aortic valve atraumatically. A pump pumps blood through from the subject's left ventricle to the subject's aorta. Other applications are also described.

Apparatus and methods are described including delivering a left-ventricular assist device to a subject's left ventricle. A tube is positioned such that a proximal portion of the tube traverses an aortic valve of the subject, and a distal portion of the tube is disposed within a left ventricle of the subject. A pump pumps blood through the tube from the subject's left ventricle to the subject's aorta such as to cause the proximal portion of the tube to be maintained in an open state, and to cause at least a portion of the tube to become curved. Other applications are also described.

Apparatus and methods are described including a ventricular assist device that includes an impeller configured to be placed inside a left ventricle of a subject. A driving magnet is coupled to a motor and is rotated by the motor. A driven magnet is magnetically coupled to the driving magnet and is rotated by the driving magnet. A drive cable extends from the driven magnet and imparts rotational motion from the driven magnet to the impeller. A set of sensors is configured to detect a magnetic phase difference between the driven magnet and the driving magnet. A computer processor receives the detected magnetic phase difference and determines a physiological parameter of the subject, at least partially in response thereto. Other applications are also described.

The invention provides a preparation method of a left ventricular assist device, the left ventricular assist device comprises a micro pump head, a transmission shaft and a driving control mechanism, the micro pump head comprises a pump head impeller and a pump head transmission assembly, the transmission shaft comprises a mandrel and a twisting shell, and the driving control mechanism comprises a twisting shell driving module and a mandrel driving module. The method comprises the following steps that a pump head transmission assembly penetrates through a pump head impeller, and the far end and the near end of the pump head impeller are fixed to the far end of the pump head transmission assembly and the far end of a twisting shell correspondingly; a mandrel is inserted into the twisting shell, and the far end of the mandrel and the near end of the pump head transmission assembly are fixed; the twisting shell driving module is arranged at the far end of the mandrel driving module and is detachably connected with the mandrel driving module, and the far end of the twisting shell driving module is in transmission connection with the near end of the twisting shell; and the far end of the mandrel driving module is in transmission connection with the near end of the mandrel. According to the scheme, the left ventricle auxiliary device with the instrument micro-size and the high blood supply flow can be obtained, and the use safety and the working efficiency of the left ventricle auxiliary device are improved.

The present disclosure relates to a RF ablation catheter for septal reduction therapy having a cooling effect, and more particularly, to a RF ablation catheter for septal reduction therapy that is for performing RF ablation, in which RF energy is applied to an interventricular septum, for septal reduction therapy such as therapy for hypertrophic cardiomyopathy, which is a disease in which an interventricular septum of the left ventricle of the heart of the animal or human body thickens, therapy that requires reduction of an interventricular septum, or therapy for ventricular tachycardia. Also, the present disclosure relates to a RF ablation catheter for septal reduction therapy having a cooling effect that is for preventing carbonization of a tissue of the body (interventricular septum) around an electrode.An exemplary embodiment of the present disclosure provides a RF catheter for septal reduction therapy, the RF catheter including: an intra-septal part in which a tapered tip which becomes thinner toward an end thereof is formed at an end of a distal part and one or more electrodes are formed at positions on an outer circumferential surface that are adjacent to the tip; and a body part which is made of a soft material and has a guidewire lumen which passes through the intra-septal part from an inlet formed at the center of the end of the tip and has an outlet formed in a side surface, a coolant inlet lumen which is connected from a proximal part to an inner portion of the intra-septal part to allow a coolant to be injected from the outside and which has an open end, and a coolant outlet lumen which communicates with the coolant inlet lumen and has an exit formed in a side surface, wherein the guidewire lumen and the coolant inlet lumen do not communicate with each other and are partitioned from each other.

The present invention relates to a radiofrequency electrode ablation catheter for ventricular septal therapy with a cooling function, which is used for performing radiofrequency electrode ablation and has a cooling function for preventing carbonization of body (ventricular septum) tissue around the electrode, wherein radiofrequency energy is applied to the ventricular septum during radiofrequency electrode ablation to perform ventricular septal therapy (e.g., therapy for hypertrophic cardiomyopathy, a disease in which the left ventricular septum of the heart of an animal or human body becomes thickened, therapy requiring reduction of the ventricular septum, or ventricular tachycardia, etc.). The radiofrequency catheter for ventricular septal therapy according to a preferred embodiment of the present invention includes a septal insertion portion and a body portion.

The disclosure relates to heart have prostheses with the reduced need of pacemaker implantation and improved means for positioning the replacement heart valve. In one aspect of the present disclosure, the stent scaffold of the valve prosthesis includes axially extending locators. The locators may be positioned within the cusp of the native aortic valve. Placement of the locators within the cusps may prevent further proximal movement of the stent scaffold into the left ventricle. By adjusting the location of the proximal end of the locators with respect to the proximal end of the stent scaffold, infra-annular placement of the stent scaffold in the aortic annulus may be assured. In another aspect, means for visualizing the positioning of replacement heart valves at an implant site inside an individual's body is disclosed.

The invention relates to a hypertrophic obstructive cardiomyopathy virtual resection operation curative effect evaluation method based on individualized computational fluid mechanics, which can give visual postoperative hemodynamic indexes, predict postoperative curative effects, find an optimal resection scheme and realize preoperative accurate intelligent evaluation. Comprising the following steps of: acquiring coronary artery enhanced computed tomography image data, acquiring a coronary artery enhanced computed tomography image of a patient, and outputting and storing the coronary artery enhanced computed tomography image in a DICOM (Digital Imaging and Communications in Medicine) format; preprocessing image data, and segmenting and reconstructing a left ventricle-outflow tract structure three-dimensional model; setting a virtual excision scheme at the fleshy part; constructing a surgical resection model, and importing the model into finite element analysis software for solving; and the virtual postoperative curative effect is visualized. Verification and curative effect prediction of a patient excision scheme can be realized, and the operation success rate of a hypertrophic obstructive cardiomyopathy patient is improved.

The invention provides an echocardiogram video abstraction method based on a hierarchical space-time attention mechanism, and the method comprises the steps: obtaining an echocardiogram, inputting the echocardiogram into an anatomy and physiological basic model of a key frame recognition task, and obtaining key frame information; inputting the key frame information into a multi-dimensional spatial-temporal feature extraction model to obtain feature information and frequency domain information; fusing the feature information and the frequency domain information; performing key frame enhancement processing on the fusion information by adopting an SE channel attention mechanism to obtain key frame anatomical feature expression; processing the key frame anatomical feature expression by adopting a key frame backtracking strategy and a classification network to obtain a key frame identification classification result; performing left ventricle segmentation on the classified image by adopting an improved U-Net left ventricle region segmentation network; estimating the area and volume of the left ventricle based on a segmentation result; fusing the estimated left ventricular area and volume by adopting a hierarchical attention mechanism and a cross-layer information fusion strategy to obtain a ventricular volume result; according to the method, through abstract extraction of the key information of the ultrasonic cardiac video, the clinical practicability of intelligent screening and auxiliary diagnosis of cardiovascular diseases based on ultrasonic is improved.

An device for treating a native valve includes a sealing element and an anchoring element. The sealing element is made from a braided mesh material. The sealing element is dimensioned to be deployed in an annulus of a native valve of a heart at a position between native valve leaflets to contact the native valve leaflets during ventricular systole to create a seal to prevent regurgitation of blood from the left ventricle to the left atrium. The sealing element is configured to both be radially expanded and radially reduced while at the position between the native valve leaflets. The anchoring element is adapted for deployment in the heart, the anchoring element coupled to the sealing element and configured to support the sealing element at the desired position between native valve leaflets.

The invention provides a left heart data analysis method and system based on image segmentation, and relates to the technical field of medical image processing. Comprising the following steps: acquiring cardiac ultrasound image data and preprocessing; performing image segmentation on the preprocessed image data to obtain a segmentation result including a left ventricle, a left ventricular wall and a left atrium; searching a boundary line of the left ventricle and the left atrium, selecting two boundary points corresponding to the minimum and maximum abscissas in the boundary line as left and right mitral valve ring points respectively, and establishing a long axis based on the mitral valve ring midpoint and the cardiac apex point; modeling the ventricle into a structure formed by superposing a plurality of discs along the long axis direction, and obtaining the diameter of the corresponding disc; based on the obtained diameters of the corresponding discs, the left ventricular volumes in the diastolic period and the systolic period are calculated respectively, and the left ventricular ejection fraction is calculated. According to the method, image segmentation and geometric modeling are fused to achieve accurate calculation of the cardiac ejection fraction, meanwhile, the accuracy of cardiac structure image segmentation is improved, and an interpretable ejection fraction estimation process is achieved.

An implantable medical device, comprising a left ventricular, LV, electrode assembly for connection to the myocardium of the left ventricle of a patient's heart and configured for application of left ventricular pacing, LVp, and for left ventricular sensing, LVs, and a control unit, configured to control the LV electrode assembly with respect to an application of LVp at a scheduled LV stimulation time, the control including inhibiting LVp during a left ventricle upper rate interval, LVURI, for T-wave protection, wherein a start of the LVURI is triggered by an LVs or LVp event. The control unit is further configured, if the scheduled LV stimulation time falls into the LVURI, to apply LVp when the LVURI lapses.

A system to treat heart failure with preserved ejection fraction (HFpEF) is described. The system comprises a blood pumping device (120) configured for implantation in a left ventricle (31) of a heart of a subject, in which the blood pumping device is configured to draw blood from a left atrium (30) into the left ventricle (31) of the heart through a mitral valve (34) upon activation, an anchoring assembly (122) for anchoring the blood pumping device to the heart, and a connector (125) rigidly connecting the anchoring assembly (122) to the blood pumping device (120) in a spaced-apart relationship to allow the blood pumping device to be positioned in the left ventricle and the anchoring assembly to be anchored at an anatomical location in or adjacent to the heart and distant to the left ventricle, wherein the system is configured for percutaneous delivery to the heart.

The utility model discloses a left ventricular wall tumor plugging device with an adjustable framework. The left ventricular wall tumor plugging device comprises a base; the supporting rod is mounted on the base; the skeleton assembly is installed on the base and comprises a plurality of skeletons arranged on the periphery of the supporting rod, the skeletons are wrapped with separation membranes, and the end of each skeleton is provided with a left ventricular wall abutting clamping part; the adjusting assembly is installed on the supporting rod and can move in the axial direction of the supporting rod; one end of the connecting rod assembly is hinged to the adjusting assembly, the other end of the connecting rod assembly is hinged to the framework assembly, and the frameworks are driven by the adjusting assembly to expand towards the radial outer side of the supporting rod. According to the left ventricular wall tumor plugging device with the adjustable framework, the unfolding angle of the framework assembly can be adjusted according to the shape of a left ventricle, and safety and stability are improved.

The invention discloses a double-balloon type left ventricle auxiliary device which comprises an inlet tube, an outer balloon, an elastic support, an inner balloon, a catheter and a connecting piece. The inlet pipe is provided with a plurality of inflow windows and a one-way valve for controlling one-way flow of blood; the outer balloon has a folded state and an expanded state, in the conveying process, the outer balloon is in the folded state and can be contained in the conveying sleeve, and when the outer balloon reaches a designated position, the outer balloon is in the expanded state; the elastic support is attached to the surface of the external balloon, the elastic deformation of the elastic support enables the external balloon to be switched between a folded state and an expanded state, and the elastic support can provide radial supporting force in the expanded state, so that the external balloon is expanded and keeps a fixed volume; the internal balloon is arranged inside the external balloon, and contraction and expansion are realized by injecting gas or liquid, so that the volumes of inner cavities of the internal balloon and the external balloon are periodically changed, and the internal balloon and the external balloon are used for sucking and discharging blood; the catheter is provided with a medium cavity and a guide wire cavity, and the medium cavity is communicated with the internal balloon.

A method of delivering a pacing lead may include locating a potential implantation site adjacent to or within the triangle of Koch region of a patient's heart. The method may include advancing a pacing lead to the potential implantation site. The pacing lead has an elongate body and a fixation element coupled to a distal portion and attachable to the right-atrial endocardium adjacent to or within the triangle of Koch region. The method may include implanting the pacing lead at the potential implantation site to or sense electrical activity of the left ventricle in the basal and / or septal region of the left ventricular myocardium of the patient's heart. The pacing lead may include a lumen configured to receive a guide wire. A sheath of a delivery system used to deliver the pacing lead may include two or more curves to facilitate implanting the pacing lead at the implantation site.

A method, for use at a mitral valve of a heart of a subject, is provided which includes advancing a transluminal sheath into a femoral vein of the subject, through an inferior vena cava of the subject, into a right atrium of the subject, and transseptally into a left atrium of the subject. A surrounding-sheath is advanced out of a distal end of the transluminal sheath, into the left atrium, and toward a commissure of the mitral valve. An anchor is implanted by advancing the anchor out of the surrounding-sheath into a left ventricle of the subject, such that the anchor helically wraps around left ventricular mitral valve tissue. The surrounding-sheath is then extracted from the heart and then, a guide wire is advanced through the transluminal sheath. Other embodiments are also described.

The invention relates to the technical field of heart structure parameter measurement, and provides a heart structure parameter acquisition method, and a heart video processing method, device and equipment, which can measure relatively accurate heart structure parameters. The method comprises the following steps: obtaining a left ventricle surrounding key point set, a left ventricle cardiac cavity structure boundary and a left ventricle surrounding tissue structure boundary according to a cardiac image map of a left ventricle long-axis section; according to the left chamber long axis direction determined by the key point set around the left chamber, an inner diameter measuring line of the left chamber is obtained; and determining the inner diameter of the left ventricle and the thickness of the tissue around the left ventricle according to the intersection information of the inner diameter measuring line and the heart cavity structure boundary and the tissue structure boundary.

Transcatheter heart valve prostheses including a dual frame stent structure are disclosed herein. The dual frame stent structure includes an inner frame and an outer frame, and an outflow end of the inner frame is attached to an outflow end of the outer frame. The inflow end of the transcatheter heart valve prosthesis is disposed within and floats freely within a patient's atrium and the outflow end of the transcatheter heart valve prosthesis does not extend or only minimally extends into the patient's left ventricle of the heart to avoid obstruction of the left ventricular outflow tract (LVOT).

An embodiment of the invention provides a system for automatically deriving a parameter of a human heart from ultrasound results. A first neural network is arranged to receive a plurality of echocardiographic images and to classify the images into one of at least a two-chamber view and a four-chamber view. A second neural network is arranged to receive echocardiographic images comprising a two- or four-chamber view and to identify the endocardial border of the left ventricle (LV) for each view. End-systole and end-diastole images are then identified and a parameter such as LV volume, ejection fraction, global longitudinal strain and regional longitudinal strain is calculated.

An inner cavity of a sheath tube and an inner cavity of a large head portion are communicated, an air bag is arranged on the outer side face of the front end portion of the sheath tube, a medical felt tube sleeve is sleeved on the sheath tube, a section of light tube is reserved between the medical felt tube sleeve and the air bag, a section of external threads is arranged on the rear end portion of the sheath tube close to the medical felt tube sleeve, and the external threads are communicated with the air bag. A medical felt gasket and a nut are sequentially arranged on the external thread, a plurality of narrow kerfs which are through front and back are formed in the peripheral side of the nut, a plurality of winding hooks are arranged on the rear side face of the nut, the winding hooks are circularly arranged to form a wire spool, the inner diameter of a base circle where the winding hooks are located is larger than the outer diameter of a base circle of the large head part, and a containing cavity is formed in the large head part. A blood blocking valve is arranged on a base of the containing cavity, an internal thread port is formed in the outer end of the large head portion, and the blood blocking valve blocks the internal thread port. When an artificial heart device is implanted, the heart of a patient does not need to be stopped and cardiac muscle does not need to be cut off, surgical operation is simplified, the surgical process is shortened, and the influence on the heart function of the patient is relieved.

An injectable hydrogel for heart failure treatment with myocardial tissue repair function and its preparation method and use are disclosed. The hydrogel is prepared by chelating alginic acid and multivalent cations. The hydrogel is loaded with an active substance for repairing cardiac injury. The active substance is recombinant humanized collagen type III. The hydrogel is administrated into the left ventricle free wall by transendocardial injection. Implanting the hydrogel in the myocardium can increase the thickness of the left ventricular wall, adjust the stress of the ventricular wall, affect the morphology of the left ventricle, and prevent or reverse left ventricular enlargement. Further, the hydrogel is loaded with a new recombinant humanized collagen material that has the function of repairing cardiac tissue injury to further improve cardiac function and promote cardiac repair.

The invention provides an integrated structure double-ventricle independent auxiliary device and an implantation method. The device comprises double inlet paths and double outlet paths which are connected, the double inlet paths are of a double-cavity structure and comprise an inner cavity and an outer cavity, the double inlet paths are implanted through the apex of the left ventricle, the inner cavity is inserted into the apex of the funnel of the right ventricle through the corresponding ventricular septum at the opening of the left ventricle, and the outer cavity is reserved in the left ventricle; and the double outlets are respectively connected with the aorta and the pulmonary artery through the artificial blood vessel by a circulation driving device. Left and right artificial ventricle admission passages are located in the heart, and channel distortion, large blood damage and proneness to thrombus caused by long admission passages are avoided; unsmooth drainage of a right chamber or right ventricle admission passage can be avoided; the right chamber is not damaged; the whole device is small in size and convenient to implant.

Methods and systems are provided for identifying cardiac cycles for evaluating left ventricle function using only image data. In one example, a method includes obtaining a sequence of medical image frames of a heart of a patient over a plurality of cardiac cycles, wherein each medical image frame depicts the same apical view of the heart, using a timing model to generate an output that is useable to label each frame of the sequence by cardiac cycle subphase and using the output to determine the suitability of each cardiac cycle for performing an automated measurement. The method may further include using the suitability of each cycle to determine if an automated measurement should be performed on each cycle, where automated measurements are performed on medical image frames corresponding to suitable cycles and automated measurements are not performed on medical image frames corresponding to unsuitable cycles.

An apparatus, comprising: a blood pump, comprising: an axial shaft (92) configured for insertion into, and rotation within, a left ventricle of a subject; an impeller (50) coupled to the axial shaft such that, as the axial shaft (92) rotates, the impeller (50) pumps blood from the left ventricle; a frame (34) surrounding the impeller (50); and a tip portion (120) coupled to a distal end of the frame (34) and comprising: a distal curved portion (349), which is configured, when deployed within the left ventricle, to lie in a plane; and a proximal curved portion (350), which is configured, when deployed within the left ventricle, not to lie in the plane and to be curved such that an angle between a distal end of the proximal curved portion (350) and the axial shaft (92) is between 100 and 170 degrees, such that the distal end of the proximal curved portion (350) points toward an apex of the left ventricle.

The invention discloses a hypertrophic cardiomyopathy (HCM) preoperative planning and operation effect evaluation method based on accurate digital labeling. The method comprises the following steps: performing digital labeling on the thickness of each wall of a left ventricle of a preoperative heart 3D digital model; according to the digital labeling result of the preoperative heart 3D digital model and the normal value of the thickness of the left ventricular wall, a doctor manually depicts the predicted resection range and confirms the predicted retention thickness; measuring the predicted resection volume, the predicted resection area and the left ventricular end diastolic volume after the predicted resection volume is resected; digitally marking the thickness of each wall of the left ventricle of the postoperative heart 3D digital model, and measuring the volume of the corresponding left ventricle in the end diastole; and taking the predicted resection range, the predicted retention thickness, the predicted resection volume, the predicted resection area and the predicted volume as first evaluation data, taking corresponding parameters of the postoperative heart 3D digital model as second evaluation data, and generating an operation evaluation result according to the conformity of the first evaluation data and the second evaluation data.