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65 results about "Retrograde Flow" patented technology
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Retrograde flow of contrast medium from the left renal vein to the left ovarian vein, and uterovaginal venous plexuses and subsequently to the right ovarian vein has been demonstrated angiographically.
Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet
Devices, systems and methods supplement, repair, or replace a native heart valve. The devices, systems, and methods employ an implant that, in use, extends adjacent a valve annulus. The implant includes a mobile neoleaflet element that occupies the space of at least a portion of one native valve leaflet. The implant mimics the one-way valve function of a native leaflet, to resist or prevent retrograde flow. The implant restores normal coaptation of the leaflets to resist retrograde flow, thereby resisting eversion and / or prolapse, which, in turn, reduces regurgitation.
Owner:VENTURE LENDING & LEASING IV
Multiple-sided intraluminal medical device
A multiple-sided medical device comprises a closed frame of a single piece of wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration that comprises a self-expanding stent. The stent is pushed from a delivery catheter into the lumen of a duct or vessel. One or more barbs are attached to the frame of the device for anchoring or to connect additional frames. A covering of fabric or other flexible material such as DACRON, PTFE, or collagen, is sutured or attached to the frame to form an occlusion device, a stent graft, or an artificial valve such as for correcting incompetent veins in the lower legs and feet. A partial, triangular-shaped covering over the lumen of the device allows the valve to open with normal blood flow and close to retrograde flow.
Owner:COOK MEDICAL TECH LLC
Implantable prosthetic valve with non-laminar flow
InactiveUS20050075725A1Prevent backflowEasy to trackStentsBalloon catheterCounter flowInsertion stent
A valve prosthesis device is disclosed suitable for implantation in body ducts. The device comprises a support stent, comprised of a deployable construction adapted to be initially crimped in a narrow configuration suitable for catheterization through the body duct to a target location and adapted to be deployed by exerting substantially radial forces from within by means of a deployment device to a deployed state in the target location, and a valve assembly comprising a flexible conduit having an inlet end and an outlet, made of pliant material attached to the support beams providing collapsible slack portions of the conduit at the outlet. The support stent is provided with a plurality of longitudinally rigid support beams of fixed length. When flow is allowed to pass through the valve prosthesis device from the inlet to the outlet, the valve assembly is kept in an open position, whereas a reverse flow is prevented as the collapsible slack portions of the valve assembly collapse inwardly providing blockage to the reverse flow. The device is configured so that retrograde flow will be altered from laminar flow and directed towards the leaflets to effect closing.
Owner:EDWARDS LIFESCIENCES CORP
Artificial valve prosthesis with improved flow dynamics
ActiveUS7618447B2Easy to removeMore turbulent flowVenous valvesBlood vesselsVenous ValvesProsthetic valve
An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and / or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
Owner:COOK MEDICAL TECH LLC
Emboli protection devices and related methods of use
ActiveUS7374560B2Improve visualizationStopping normal blood flowStentsDilatorsRetrograde FlowEmbolization material
An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly. If necessary to increase retrograde flow, the coronary sinus may be at least partially occluded. Alternatively, antegrade flow may be permitted while flow is occluded at the treatment site.
Owner:ST JUDE MEDICAL CARDILOGY DIV INC
Devices, systems, and methods for retaining a native heart valve leaflet
InactiveUS7527646B2Prevents and reduces flowPrevents and reduces and regurgitationHeart valvesBone implantRetrograde FlowPlasma viscosity
Devices, systems and methods retain a native heart valve leaflet to prevent retrograde flow. The devices, systems, and methods employ an implant that, in use, rests adjacent a valve annulus and includes a retaining structure that is sized and shaped to overlay at least a portion of one or more native valve leaflets. The retaining structure retains the leaflet or leaflets it overlays, to resist leaflet eversion and / or prolapse. In this way, the implant prevents or reduces regurgitation. The implant does not interfere significantly with the opening of and blood flow through the leaflets during periods of antegrade flow.
Owner:VENTURE LENDING & LEASING IV
Apparatus and methods for treating stroke and controlling cerebral flow characteristics
InactiveUS6929634B2Quickly and efficiently treat cerebral occlusionConvenient introductionStentsBalloon catheterThrombusRetrograde Flow
Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in the common carotid artery of the hemisphere of the cerebral occlusion. Retrograde flow may be provided through the catheter to effectively control cerebral flow characteristics. Under such controlled flow conditions, a thrombectomy device may be used to treat the occlusion, and any emboli generated are directed into the catheter.
Owner:WL GORE & ASSOC INC
Patient-specific hemodynamics of the cardio vascular system
ActiveUS20100241404A1Minimize model instabilityMore benefitMedical simulationAnalogue computers for chemical processesInstabilityRetrograde Flow
A noninvasive patient-specific method is provided to aid in the analysis, diagnosis, prediction or treatment of hemodynamics of the cardiovascular system of a patient. Coronary blood flow and pressure can be predicted using a 3-D patient image-based model that is implicitly coupled with a model of at least a portion of the remaining cardiovascular system. The 3-D patient image-based model includes at least a portion of the thoracic aorta and epicardial coronaries of the patient. The shape of one or more velocity profiles at the interface of the models is enforced to control complex flow features of recirculating or retrograde flow thereby minimizing model instabilities and resulting in patient-specific predictions of coronary flow rate and pressure. The invention allows for patient-specific predictions of the effect of different or varying physiological states and hemodynamic benefits of coronary medical interventions, percutaneous coronary interventions and surgical therapies.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
Devices, systems, and methods for supplementing, repairing, or replacing a native heart valve leaflet
Owner:VENTURE LENDING & LEASING IV
Stent for arterialization of the coronary sinus and retrograde perfusion of the myocardium
The present invention concerns a novel stent and a method for communicating oxygenated blood directly from the left ventricle to the coronary sinus to provide retrograde perfusion to the myocardium. The stent is placed substantially within the coronary sinus with its trailing end protruding into the right atrium and the leading end protruding into the left ventricle. The stent has a smaller passageway at or near the trailing (right ventricular) end and at or near the leading (left ventricle) end, and has a covering at the trailing end. The smaller passageway and the cover at the trailing end to promote retrograde flow into the venous system of the hear and specifically the myocardium of the left ventricle and to reduce a significant left-to-right shunt.
Owner:MARTIN ERIC C
Artificial Valve Prosthesis with Improved Flow Dynamics
ActiveUS20070260327A1Easy to removePrevent stagnantVenous valvesBlood vesselsProsthetic valveVenous Valves
An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and / or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
Owner:COOK MEDICAL TECH LLC
Devices, systems, and methods for reshaping a heart valve annulus
InactiveUS20060106456A9Reduce the amount requiredRecovery functionDiagnosticsAnnuloplasty ringsRetrograde FlowBiomedical engineering
Devices, systems, and methods employ an implant that is sized and configured to attach to the annulus of a dysfunctional heart valve annulus. In use, the implant extends across the major axis of the annulus above and / or along the valve annulus. The implant reshapes the major axis dimension and / or other surrounding anatomic structures. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets, which, in turn, reduces retrograde flow or regurgitation. The implant improves function to the valve, without surgically cinching, resecting, and / or fixing in position large portions of a dilated annulus, or without the surgical fixation of ring-like structures.
Owner:VENTURE LENDING & LEASING IV
Stent for arterialization of the coronary sinus and retrograde perfusion of the myocardium
The present invention concerns a novel stent and a method for communicating oxygenated blood directly from the left ventricle to the coronary sinus to provide retrograde perfusion to the myocardium. The stent is placed substantially within the coronary sinus with its trailing end protruding into the right atrium and the leading end protruding into the left ventricle. The stent has a smaller passageway at the trailing (right ventricular) end and at the leading (left ventricle) end, and has a covering at the trailing end. The smaller passageway and the cover at the trailing end to promote retrograde flow into the venous system of the heart and specifically the myocardium of the left ventricle and to reduce a significant left-to-right shunt.
Owner:MARTIN ERIC C
Implantable prosthetic valve with non-laminar flow
Owner:EDWARDS LIFESCIENCES CORP
Embolization protection system for vascular procedures
Apparatus and methods are described for effective removal of emboli or harmful fluids during vascular procedures, such as angiography, balloon angioplasty, stent deployment, laser angioplasty, atherectomy, intravascular ultrasonography and other therapeutic and diagnostic procedures. A catheter with an occluder mounted at its distal end creates an occlusion proximal to the lesion. The catheter provides a pathway for introducing a treatment catheter. Prior to, during or subsequent to the procedure, suction is activated to establish retrograde flow to remove emboli from the site. Additionally, a thin catheter with a distal fluid ejection nozzle maybe introduced distal to the treatment site to rinse emboli from the treatment site. The suction flow and / or ejected fluid flow may be varied in a pulsatile manner to simulate regular blood flow and / or perturb settled emboli into being captured that may otherwise not be collected. The method establishes a protective environment before any devices enter the site to be treated.
Owner:CHINE LLC
Medical connector
Owner:ICU MEDICAL INC
Method of reshaping a heart valve annulus using an intravascular device
Devices, systems, and methods employ an implant that is sized and configured to attach in, on, or near the annulus of a dysfunctional heart valve. In use, the implant extends either across the minor axis of the annulus, or across the major axis of the annulus, or both. The implant restores to the heart valve annulus and leaflets a more functional anatomic shape and tension. The more functional anatomic shape and tension are conducive to coaptation of the leaflets, which, in turn, reduces retrograde flow or regurgitation.
Owner:VENTURE LENDING & LEASING IV
Devices, systems, and methods for retaining a native heart valve leaflet
InactiveUS20060069430A9Avoid many problemsPrevents and reduces flowHeart valvesBlood flowRetrograde Flow
Devices, systems and methods retain a native heart valve leaflet to prevent retrograde flow. The devices, systems, and methods employ an implant that, in use, rests adjacent a valve annulus and includes a retaining structure that is sized and shaped to overlay at least a portion of one or more native valve leaflets. The retaining structure retains the leaflet or leaflets it overlays, to resist leaflet eversion and / or prolapse. In this way, the implant prevents or reduces regurgitation. The implant does not interfere significantly with the opening of and blood flow through the leaflets during periods of antegrade flow.
Owner:VENTURE LENDING & LEASING IV
Emboli protection devices and related methods of use
An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly. If necessary to increase retrograde flow, the coronary sinus may be at least partially occluded. Alternatively, antegrade flow may be permitted while flow is occluded at the treatment site.
Owner:ST JUDE MEDICAL CARDILOGY DIV INC
Prosthesis having a sleeve valve
Disclosed is a pressure sensitive prosthesis that includes a tubular member having a passageway extending therethrough and a sleeve attached about one end of the tubular member. The sleeve functions as a one-way valve to permit fluid flowing through the sleeve lumen in a first direction and under a first pressure, while collapsing in response to fluid flowing in a second direction when the pressure thereof exceeds that of the first direction or pressure. One aspect of the invention includes an esophageal anti-reflux expandable prosthesis wherein the sleeve is adapted to invert back through the tubular stent frame to permit belching or vomiting (fluid or materials under a third, significantly higher pressure). Another aspect of the invention includes a tubular drainage stent, such as a biliary or urethral stent in which the sleeve opens to permit passage of fluids, then collapses to prevent retrograde flow.
Owner:COOK MEDICAL TECH LLC
Needleless Luer activated medical connector
A medical fluid flowline connector comprised of axially aligned relatively rotatable male and female Luer parts and an axially compressible elastomeric seal therebetween. An elastomeric stopper may be provided in the female Luer, the stopper having a swabbable end urged outwardly of the female Luer. The stopper is guided on an axially extending elongated flow conducting insert which has an end which contacts a deformable slit in the swabbable end of the stopper to ensure deformation and opening of the slot as a male Luer at the end of a fluid flowline is pushed against the stopper. The stopper skirt is deformed and displaced into annular space between the female Luer and the insert, the stopper having bellows like walls which engage the female Luer and insert. A retrograde flow preventer may be positioned in the fluid flow path comprising a resilient member having a perforation which remains closed when its exterior surface is exposed to retrograde flow of medication or blood and which may open when its interior surface is exposed to sufficient negative flow pressures as when drawing blood.
Owner:HALKEY ROBERTS CORP
Prosthetic valve with pores
Prosthetic valves for regulating fluid flow are provided. The valves have at least one leaflet that includes a plurality of pores that allow a quantity of retrograde flow to pass through the leaflet when the valve is in a closed configuration.
Owner:COOK MEDICAL TECH LLC
Systems for sensing retrograde flows of bone fill material
InactiveUS20070118144A1Inhibit migrationReduction procedureDiagnosticsSpinal implantsCounter flowFilling materials
The present invention relates in certain embodiments to medical devices, systems and methods for use in osteoplasty procedures, such as vertebral compression fractures. One device for delivering a bone fill material to a bone, such as a vertebra, includes an elongated sleeve configured for introduction into a bone, the elongated sleeve having an opening to allow a flow of bone fill material therethrough into the bone. The device also includes at least one sensor disposed on an exterior surface of the sleeve, the sensor being configured to sense a retrograde flow of bone fill material about the sleeve and proximate the at least one sensor. One system for treating a bone includes such a device and a controller configured to receive signals from the sensor and controls at least one parameter of bone fill material flow into the bone based at least in part on said signals.
Owner:DFINE INC
Prosthetic valve with pores
Prosthetic valves for regulating fluid flow are provided. The valves have at least one leaflet that includes a plurality of pores that allow a quantity of retrograde flow to pass through the leaflet when the valve is in a closed configuration.
Owner:COOK MEDICAL TECH LLC
Proximal catheter assembly allowing for natural and suction-assisted aspiration
The present invention is directed to a proximal catheter assembly that is configured to facilitate aspiration through a catheter lumen. The proximal catheter assembly enables natural aspiration to be achieved within the catheter lumen, for example, using an arterial-venous shunt, and further enables suction-assisted aspiration or infusion to be applied through the catheter lumen. This allows a physician to provide a substantially continuous level of retrograde flow within a vessel during a medical procedure without damaging the vessel wall, while providing the option of suction-assisted aspiration, when necessary, to further influence the level of aspiration within the vessel.
Owner:WL GORE & ASSOC INC
Needleless luer activated medical connector
A medical fluid flowline connector comprised of axially aligned relatively rotatable male and female Luer parts and an axially compressible elastomeric seal therebetween. An elastomeric stopper may be provided in the female Luer, the stopper having a swabbable end urged outwardly of the female Luer. The stopper is guided on an axially extending elongated flow conducting insert which has an end which contacts a deformable slit in the swabbable end of the stopper to ensure deformation and opening of the slot as a male Luer at the end of a fluid flowline is pushed against the stopper. The stopper skirt is deformed and displaced into annular space between the female Luer and the insert, the stopper having bellows like walls which engage the female Luer and insert. A retrograde flow preventer may be positioned in the fluid flow path comprising a resilient member having a perforation which remains closed when its exterior surface is exposed to retrograde flow of medication or blood and which may open when its interior surface is exposed to sufficient negative flow pressures as when drawing blood.
Owner:HALKEY ROBERTS CORP
Prosthetic valve that permits retrograde flow
ActiveUS7402171B2Block fluid flowHigh acceptanceVenous valvesBlood vesselsProsthetic valveProsthesis
A prosthetic valve for regulating fluid flow through a body vessel is provided. The valve includes an expandable support frame and a valve leaflet, and includes at least one opening that permits a controlled amount of retrograde flow through the valve when the valve is in a closed configuration.
Owner:COOK MEDICAL TECH LLC
Systems and methods to improve perfusion pressure during endovascular intervention
The invention relates to systems and methods to improve perfusion flow and pressure during endovascular intervention. In particular, the invention relates to catheters that enable both antegrade and retrograde flow through the catheter during a recanalization procedure and specifically at the step in a procedure where a clot is being withdrawn. Additionally, the invention provides systems for supplying fluids and fluid compositions to improve nutrition to ischemic brain.
Owner:MG STROKE ANALYTICS INC
Methods for sensing retrograde flows of bone fill material
InactiveUS20070162043A1Inhibit migrationReduction procedureDiagnosticsSpinal implantsFilling materialsRetrograde Flow
The present invention relates in certain embodiments to medical devices and methods for use in osteoplasty procedures, such as vertebral compression fractures. One method for treating an abnormal vertebra includes flowing a bone fill material through an introducer into a vertebral body along a first direction and sensing a flow of said bone fill material about an outer surface of the introducer in a second direction different from said first direction. In other embodiments, a signal is generated to alert a physician of said bone fill material flow in said second direction.
Owner:DFINE INC
Flow-Deflecting Prosthesis for Treating Venous Disease
The disclosure relates to a flow-deflecting medical device comprising a support structure and at least one flow-deflecting member attached to the support structure. The flow-deflecting member is at least partially evertible between a first position and a second position. In the first position, antegrade flow contacts the antegrade surface of the flow-deflecting member, urging the flow-deflecting member proximally in the body vessel such that antegrade flow is substantially uninterrupted. In the second position, retrograde flow contacts the retrograde surface of the flow-deflecting member, urging the flow-deflecting member distally in the body vessel, such that retrograde flow is received and redirecting by the flow-deflecting member. Also provided is a method for treating a body vessel valve-related condition comprising implanting a flow-deflecting medical device proximal to a native valve.
Owner:COOK MEDICAL TECH LLC
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