5 results about "Coronary flow" patented technology

This invention discloses a method and system for extracting coronary artery blood flow signals based on anatomical structure segmentation and adaptive filtering. The method includes: simultaneously acquiring B-mode images and Doppler data of the heart and aligning them temporally; using a deep learning model to segment anatomical structures and generate a mask; constructing a clutter shield based on the mask to filter out strong blood flow signals from the cavities; extracting the epicardial boundary to locate candidate coronary artery regions; constructing a spatiotemporal matrix within the candidate regions; using an adaptive truncated singular value decomposition algorithm to separate tissue clutter and obtain coronary blood flow signals; and finally, outputting quantitative indicators after vascular morphology confirmation and angle correction based on the blood flow centerline. This invention effectively solves the problem of extracting weak coronary artery signals under strong interference through physical-level shielding and adaptive filtering, improving the accuracy and robustness of detection.

This invention belongs to the field of biomedical technology, specifically relating to a composition for treating ischemic heart disease and its application. This invention combines two or more of ginsenoside Rg1, ginsenoside Rb1, ginsenoside Re, and notoginsenoside R1, which can significantly downregulate the levels of myocardial enzymes, aspartate aminotransferase (AST), creatine kinase (CK), and lactate dehydrogenase (LDH) in myocardial coronary effusion, with an inhibitory effect significantly higher than that of a single saponin component and the positive control drug verapamil. Simultaneously, the composition exhibits better recovery capabilities for coronary flow (CF), left ventricular developmental pressure (LVDP), maximum rate of decrease in left ventricular pressure (-dp / dtmax), and heart rate (HR) in myocardial coronary effusion. Therefore, the composition can alleviate and treat myocardial ischemia-reperfusion injury through multiple targets and mechanisms, fundamentally inhibiting the development of ischemic heart disease.

The present application relates to the technical field of medical evaluation. A device for evaluating the function of coronary arteries is provided, comprising: a data acquisition module for synchronously acquiring multi-modal physiological data of a target coronary artery; the data acquisition module comprises a contrast image acquisition unit, a pressure waveform acquisition unit, an electrocardiogram acquisition unit and a blood flow velocity acquisition unit; a data processing module is in communication connection with the data acquisition module, and is internally provided with a hemodynamic parameter calculation circuit for filtering, fusing and parameter operation on the multi-modal physiological data, and outputs instantaneous blood flow state parameters, instantaneous blood flow resistance parameters, blood flow dynamic simulation parameters and reserve function derivative parameters; an evaluation module is in communication connection with the data processing module, and is used for outputting quantitative evaluation data of the function of the coronary artery based on a preset hardware evaluation model. The device can comprehensively and quantitatively and accurately evaluate the blood flow and function of the coronary artery, while maintaining high accuracy, reducing operation complexity and cost burden.

Provided is a coronary blood flow measurement device capable of acquiring significant information for determination of ischemic heart disease caused by stenosis or the like in a coronary blood vessel on the basis of measurement of a blood flow (coronary blood flow) in a blood vessel (coronary blood vessel) of a heart. This coronary blood flow measurement device (10) includes: a CFR acquisition means (12) for acquiring a calculated value of coronary blood flow reserve (CFR); and a cCFR calculation means (14) for obtaining a blood pressure correction CFR (cCFR) by converting the calculated value of the coronary blood flow reserve (CFR) acquired by the CFR acquisition means into a value under a condition of an arbitrary specific value (ΔPs) of an arteriovenous pressure difference (ΔP(a-v)) by using a linear relationship between a maximum hyperemia coronary blood flow (Q(hyp.)) and the arteriovenous pressure difference (ΔP(a-v)).

A medical image processing apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to obtain medical image data related to a coronary artery of a subject. The processing circuitry is configured to derive a value of a blood flow parameter indicating hemodynamics of the coronary artery, on the basis of the medical image data. The processing circuitry is configured to display information indicating a change in the value of the blood flow parameter along the coronary artery, by using a graph of which the vertical axis expresses values of the blood flow parameter and of which the horizontal axis corresponds to the distance direction along the coronary artery and is configured to further display supplementary information indicating the structure of the coronary artery together with the graph.