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23results about How to "Restore elasticity" patented technology

Anti-aging and repairing cosmetic composition as well as preparation method and application thereof

The invention belongs to the technical field of cosmetics, and particularly discloses an anti-aging and repairing cosmetic composition as well as a preparation method and application thereof. The cosmetic composition is prepared from the following raw materials in parts by weight: 0.05 to 1.5 parts of an ergothioneine pine mushroom extract, 1 to 10 parts of oat firming protein, 0.01 to 1 part of Marilong eight-treasure raw powder, 0.001 to 1 part of tetrahydromethylpyrimidine carboxylic acid, 0.000001 to 0.01 part of conopeptide, 0.00001 to 0.1 part of acetyl hexapeptide-8, 0.01 to 1 part of D-panthenol, 0.01 to 3 parts of nicotinamide and 0.01 to 1 part of sodium hyaluronate. The cosmetic composition provided by the invention simultaneously has multiple effects of immediate wrinkle removal, long-term anti-aging wrinkle removal, barrier repair and the like, the anti-aging repair effect of the product is greatly improved, and the maintenance process of consumers is effectively simplified. The prepared eye cream is small in irritation and good in anti-aging and repairing effects.
Owner:WUHAN MAYINGLONG MASSIVE HEALTH CO LTD

Composition capable of rapidly removing dark circles and resisting aging for long time and application of composition

PendingCN119454495AAvoid radiation damageReduce osmotic pressureOrganic active ingredientsCosmetic preparationsArginineNicotinamide mononucleotide
The invention discloses a long-acting anti-aging composition capable of quickly removing dark circles and application of the composition. The composition is prepared from the following components: beta-nicotinamide mononucleotide, glutathione, acetyl hexapeptide-8, acetyl tetrapeptide-5, snake venom-like peptide, arginine / lysine polypeptide, tocopheryl acetate and ergothioneine. According to the present invention, multiple functions are adopted, such that the effects of dark circle removing, repair, elasticity recovery, aging resistance and the like are provided so as to block the generation of dark circle, and the normal function of skin is ensured. The composition disclosed by the invention has the effect of quickly removing dark circles, and when the eye cream contains the composition, the eye cream can effectively remove the dark circles and has an obvious and quick effect within 15 minutes; after being used for a long time, the eye mask can remove dark circles and play a good control role.
Owner:WANWANSHENG BIOTECHNOLOGY (SHENZHEN) CO LTD

Soothing and moisturizing compound as well as preparation method and application thereof

PendingCN119606844ANo longer prone to allergieseliminate discomfortCosmetic preparationsToilet preparationsBiotechnologyQuisqualis indica
The invention relates to the technical field of raw materials of skin care products, and particularly discloses a soothing and moisturizing compound as well as a preparation method and application thereof. The preparation method of the soothing and skin-moistening compound comprises the following steps: 1) mixing rice, cornflower, quisqualis indica, cashew nut and water, heating and extracting to obtain a pre-extract; (2) adding compound bacteria into the pre-extract, and fermenting to obtain a fermented product; the invention discloses a soothing and skin-moistening compound and a preparation method thereof.The soothing and skin-moistening compound has the advantages that the soothing and skin-moistening compound is prepared from compound bacteria of streptomyces cinereorubens fructose fermentation subspecies, fermented lactobacillus mucus and pediococcus pentosaceus, and the soothing and skin-moistening compound is more remarkable in soothing effect.
Owner:MINGYU (GUANGDONG) COSMETICS TECH CO LTD

Combustion slag collecting device of singeing machine

The utility model relates to the field of singeing machines, and discloses a burning slag collecting device of a singeing machine, which comprises a support frame, a collecting mechanism and a blowing mechanism are arranged at the top of the support frame, the collecting mechanism comprises a burner, the outer wall of the burner is fixedly connected with the outer wall of the support frame, the top of the support frame is fixedly connected with a support cover, and the support cover is fixedly connected with the blowing mechanism. A dust suction pipe is fixedly connected to the top of the inner wall of the supporting cover, a dust suction cover is fixedly connected to the bottom end of the dust suction pipe, a fixing pipe is fixedly connected to the left side of the dust suction pipe, and a dust suction fan is fixedly connected to the inner wall of the fixing pipe. According to the device disclosed by the utility model, by arranging the collecting mechanism, combustion slag generated in the singeing process can be sucked, the filter screen plate can effectively filter and intercept the combustion slag and impurities and can prevent large-particle impurities and the combustion slag from continuously flowing along with air flow, and the scraper plate can scrape off the impurities filtered on the filter screen plate, so that the impurities are prevented from blocking filter holes; and the stability and continuity of the filtering effect are ensured.
Owner:JIAXING LEHAO SILK TECH CO LTD

Anti-wrinkle composition, anti-wrinkle essence and application of anti-wrinkle composition and anti-wrinkle essence

The invention provides an anti-wrinkle composition, anti-wrinkle essence and application of the anti-wrinkle composition and the anti-wrinkle essence, and belongs to the technical field of cosmetics. The anti-wrinkle composition disclosed by the invention is prepared from the following components in parts by mass: 1 to 3 parts of yeast extract and 3 to 8 parts of acetyl hexapeptide-8. The yeast extract and the acetyl hexapeptide-8 are synergistically matched, so that the inhibition rate on elastinase can be increased, wrinkles on facial skin, scalp skin and neck skin can be reduced or the wrinkles can be prevented, the skin elasticity can be recovered, the collagen strength can be improved, and the skin barrier function and the hydration moisturizing effect can be improved. The anti-wrinkle active composition provided by the invention can be used for preparing face and neck care products with anti-wrinkle and anti-aging effects.
Owner:SHANXI ZHENDONG HEALTH CARE TECHNOLOGY CO LTD

Aged leather softening agent based on lanolin / soybean polysaccharide as well as preparation method and application of aged leather softening agent

The invention belongs to the technical field of leather softening agents, and particularly relates to an aged leather softening agent based on wool fat / soybean polysaccharide as well as a preparation method and application of the aged leather softening agent. The softening agent is prepared by mixing glycerol, amino silicon oil, wool fat and a soybean polysaccharide aqueous solution. The preparation method of the softening agent comprises the following steps: mixing a soybean polysaccharide aqueous solution with glycerol to obtain a first mixture; adding amino silicon oil into the first mixture, and mixing to obtain a second mixture; and adding molten wool fat into the second mixture, and mixing to obtain the aged leather softening agent based on wool fat / soybean polysaccharide. The lanolin / soybean polysaccharide-based aged leather softening agent is prepared from pure natural soybean polysaccharide, glycerol, amino silicon oil and lanolin, so that deep penetration of aged leather and effective filling of fiber gaps are realized, and the softness, color and luster and heat resistance of the aged leather can be remarkably improved.
Owner:ZHENGZHOU UNIV

Repsox-loaded microneedle as well as preparation method and application thereof

The invention relates to the technical field of medicines, in particular to a Repsox-loaded microneedle as well as a preparation method and application thereof. The method specifically comprises the following steps: (1) mixing water with polyvinyl alcohol with low polymerization degree and low alcoholysis degree, then sequentially adding Repsox and hyaluronic acid, and mixing to obtain a needle tip solution; (2) mixing water with high-polymerization-degree and high-alcoholysis-degree polyvinyl alcohol, then adding a bacteriostatic agent, and mixing to obtain a substrate solution; and (3) adding the needle tip solution into a mold, carrying out primary centrifugation and curing, then adding the substrate solution, and carrying out secondary centrifugation, drying and demolding. The microneedle prepared by the invention has the technical effect of improving the thickness of the aged skin, so that a specific action way of the microneedle in a skin regeneration process is disclosed, and a more convenient method is provided for improving the thickness of the skin.
Owner:SOUTHWEST JIAOTONG UNIV

Freckle-removing and whitening essence and preparation method thereof

The invention relates to the technical field of skin care products, and aims to provide freckle-removing and whitening essence and a preparation method thereof, and the freckle-removing and whitening essence comprises 0.5-3.5% of a whitening and freckle-removing agent, 5-10% of a humectant, 2-5% of a skin conditioner, 0.2-0.6% of a preservative, 0.1-0.3% of a thickener, 0.1-0.2% of a pH regulator, 0.02-0.05% of a chelating agent and the balance of water. The traditional Chinese medicine composition has a good tyrosinase activity inhibition effect, and can whiten and tender the skin and moisturize and nourish the skin after being used.
Owner:GUANGZHOU CHANYAN BIOLOGICAL TECH CO LTD

Traditional Chinese medicine preparation composition based on cell repair and preparation method thereof

The invention discloses a traditional Chinese medicine preparation composition based on cell repair and a preparation method thereof, and belongs to the field of biological medicine. The traditional Chinese medicine preparation composition is prepared from honey, astragalus membranaceus, lithospermum erythrorhizon, angelica sinensis, pogonatherum cnidii, herba epimedii, cynomorium songaricum, shaved cinnamon bark, freshwater sponge, camphor, cordyceps sinensis, saussurea involucrata, ginseng, rhodiola rosea, elecampane and rhizoma cimicifugae, and the preparation method comprises the steps of raw material preparation, coarse grinding, mixing, extraction, filtration, concentration, drying, fine grinding, preparation forming and other process treatment. The traditional Chinese medicine preparation can effectively resist skin aging, improve the skin quality, enable the skin to recover elasticity and luster, give full play to the effects of nourishing, oxidation resistance, blood circulation promotion and cell repair of traditional Chinese medicinal materials, deeply nourish the skin and achieve the effect of delaying senescence. The preparation method is simple and easy to implement and low in cost, and has a good application prospect.
Owner:XIAN XUANYUZIJIN PHARM CO LTD

A traditional Chinese medicine composition for treating scald and a preparation method thereof

ActiveCN121466250BHas rapid-acting analgesic effectNo further damage will occurHydroxy compound active ingredientsAerosol deliveryGanoderma lucidumArnebia
The present application relates to the technical field of traditional Chinese medicine composition, and particularly to a traditional Chinese medicine composition for treating scald and a preparation method thereof, and provides a traditional Chinese medicine composition for treating scald, which comprises: honeysuckle stem, lotus leaf, kadsura coccinea, one mouth clock, rehmannia glutinosa, turmeric, phellodendron, raw sanguis draconis, angelica tail, radix violae, ganoderma lucidum, plum slice, natural white beeswax and camellia oil. The scald treatment medicine prepared from the traditional Chinese medicine composition has the advantages of rapid analgesia, no adhesion after dressing change, promotion of wound healing, short healing period, scar repair function and stable quality.
Owner:BEIHUA UNIV

Anti-wrinkle composition and application thereof

PendingCN119564584Arestore elasticityimprove health statusCosmetic preparationsToilet preparationsCutaneous laxityRutin
The invention relates to an anti-wrinkle composition and application thereof. The anti-wrinkle composition comprises a nostoc sphaeroids kutz extract, hydroxydecyl ubiquinone, rutin and raspberry ketone glucoside. The invention creatively finds that the common nostoc extract, the hydroxydecyl ubiquinone, the rutin and the raspberry ketone glucoside are matched for use and have a synergistic effect, so that the composition has good wrinkle-removing and anti-oxidation effects, and can recover skin elasticity, accelerate skin cell viability, reduce skin laxity and recover the health state of the skin.
Owner:GUANGZHOU RUI SEN BIOTECHNOLOGY CO LTD

Passivating agent for inactivating free radicals of recycled asphalt as well as preparation method and application of passivating agent

The invention relates to a passivating agent for inactivating free radicals of recycled asphalt as well as a preparation method and application of the passivating agent, and relates to the technical field of resource utilization of road waste asphalt concrete. The passivator for recycling asphalt free radical inactivation comprises the following raw materials: 100 parts of allylamine, 80-160 parts of hydroquinone, 2-5 parts of a first catalyst and 0.2-2 parts of a stabilizer, the allyl amine is a mixture of monoallyl amine, diallyl amine and triallyl amine. By preparing the free radical passivator rich in carbon-carbon double bonds, on one hand, active inhibition of the free radical induced aging effect of the aged asphalt in the recycled asphalt pavement is achieved, and aging of the asphalt is remarkably delayed; on the other hand, by introducing carbon-carbon double bonds on the molecular chain of the free radical passivator, the elasticity of the aged asphalt is recovered, comprehensive repair of the performance of the aged asphalt is achieved, the regeneration utilization rate of the waste asphalt mixture is remarkably increased, and important theoretical and practical significance is achieved.
Owner:CHONGQING JIAOTONG UNIV

Eye ointment for improving eyesight and relieving asthenopia and preparation method thereof

The invention relates to the technical field of oculents, in particular to an oculents for improving eyesight and relieving asthenopia and a preparation method of the oculents. The traditional Chinese medicine composition is prepared from flos eriocauli, tribulus terrestris, ginseng, lavender, lemon grass, semen cassiae, flos carthami, flos chrysanthemi, pearl, borax, mint, calculus bovis factitius, menthol, borneol, vitamins and xanthophyll. The flos eriocauli and the tribulus terrestris can effectively achieve the effects of improving eyesight, removing nebula, diminishing swelling and stopping lacrimation, and 6-10 parts of flos carthami and flos chrysanthemi are matched, so that the pearl and the mint can accelerate the blood circulation of eyes; according to the present invention, with the application of the vitamin C and the xanthophyll, the eyes can be further protected, the cataract, the macular degeneration and the like can be prevented, the anti-oxidation effect can be provided, and the immunity of the eyes can be improved.
Owner:JILIN PUHUI PHARMACEUTICAL TECHNOLOGY CO LTD

Traditional Chinese medicine composition with skin repairing effect and preparation method thereof

The invention relates to a traditional Chinese medicine composition with a skin repairing effect, the traditional Chinese medicine composition is composed of effective components and medically acceptable auxiliary materials, and the effective components are prepared from the following raw material medicines in parts by weight: 10-35 parts of solanum lyratum, 45-75 parts of angelica dahurica, 20-60 parts of aloe, 10-30 parts of codonopsis pilosula, 10-30 parts of ligusticum wallichii and 10-30 parts of flowers. The traditional Chinese medicine composition disclosed by the invention has a synergistic effect, has the effects of relieving skin inflammation, remarkably increasing the water content of skin, delaying the loss of skin collagen, relieving wrinkles and improving the dry state of the skin, and has remarkable effects of preventing and treating water shortage and dryness of the skin and repairing damaged skin.
Owner:ZHEJIANG PROVINCIAL LITONGDE HOSPITAL (ZHEJIANG PROVINCIAL INST OF MENTAL HEALTH)

Female antibacterial liquid containing lucid ganoderma extract and preparation method of female antibacterial liquid

The invention discloses female antibacterial liquid containing a lucid ganoderma extract and a preparation method of the female antibacterial liquid. The female antibacterial liquid is prepared from the following raw materials in percentage by weight: 0.134% of parachlorometaxylenol, 1.1% of a radix sophorae flavescentis extract, 20% of a malt extract, 5% of the lucid ganoderma extract, 42% of a grape fruit extract, 24.52% of olive oil, 5% of simmondsia chinensis seed oil, 0.45% of zedoary turmeric oil, 1.5% of eucalyptus oil and 0.3% of borneol. The ganoderma lucidum extract is extracted by adopting a water extraction and alcohol precipitation method, and the content of ganoderma lucidum polysaccharide is not less than 20%; the grape fruit extract is extracted by adopting a supercritical carbon dioxide extraction technology; the sophora flavescens extract is extracted by adopting an ethanol extraction method, and the matrine content is not less than 0.5%. The invention has the advantages that: the anti-bacterial and nourishing effects are integrated, the anti-bacterial effect is improved and the nourishing and protecting effects of the product are enhanced by carefully selecting a plurality of natural plant extracts and optimizing the proportion, and the anti-bacterial and nourishing mask is suitable for being used on sensitive skin; meanwhile, the stability and the use experience of the product are ensured by the fine preparation process, and the overall stability and the safety of the product are improved.
Owner:HANGZHOU GUOEN BIOTECHNOLOGY CO LTD

Preparation method of neural stem cell homogenate and application of neural stem cell homogenate in repairing skin light injury and light aging

PendingCN119530154ARepair rednessRepair shaving
The invention relates to a preparation method and application of neural stem cell homogenate. The method comprises the following steps: extracting primary neural stem cells from cerebral cortex of fetal rats with the gestational age of 11.5-15.5 days; culturing the extracted primary neural stem cells, adjusting the concentration of growth factors for culture by adopting a half-volume liquid change mode, and culturing to P1 generation; and repeatedly freezing and thawing the P1-generation neural stem cells to obtain the neural stem cell homogenate. According to the method, the neural stem cell homogenate can be efficiently obtained, and the neural stem cell homogenate has a repairing effect on skin injury of a photoaged mouse constructed by medium-wave ultraviolet rays (UVB) and has a dose effect.
Owner:TAOKANG INST OF NEUROLOGY (XIAMEN) CO LTD

Repair method of rubber profile with fabric on hollow closed surface

PendingCN119590000Arestore elasticityrestore sealing performanceRepair materialMaterial resources
The invention provides a method for repairing a rubber profile with a fabric on a hollow closed surface. The method comprises the following steps: preparing a repairing material, cleaning and drying, polishing and protecting, sewing, determining an external expansion area, cutting a repairing strip, laminating, heating, pressurizing and the like. The method has the characteristics that the operation is simple, the product does not need to be completely disassembled, the damaged rubber profile can be quickly repaired, manpower and material resources are remarkably saved in practical application, and the assembly efficiency of a user is greatly improved; for a large profile which is dozens of meters and even hundreds of meters long, the technology can ensure excellent sealing performance on the basis of keeping the original structure of the profile. According to the airtight test verification, the repaired product can meet the airtight requirement, the repaired part does not have the abnormal conditions such as falling or cracking, the reliability is high, and the service life of the rubber profile is effectively prolonged.
Owner:NORTHWEST RUBBER & PLASTIC RES & DESIGN INST CO LTD

Preparation method and application of trillium tschonoskii yeast / probiotic fermentation liquor

The invention discloses a preparation method and application of trillium tschonoskii yeast / probiotic fermentation broth, trillium tschonoskii is fermented by adopting saccharomyces cerevisiae and compound probiotics in a combined manner, all functional components and activity of plants are effectively reserved, and loss of active components possibly caused by a traditional extraction method is avoided. The prepared trillium tschonoskii yeast / probiotic fermentation liquor does not contain chemical components, the safety of the product is ensured, and the trillium tschonoskii yeast / probiotic fermentation liquor can be directly used as a mask, essence or toner. Compared with other products on the market, the prepared trillium tschonoskii yeast / probiotic fermentation liquor is more natural and does not bring any side effect to the skin. In addition, macromolecular components are decomposed into smaller molecules in the probiotic fermentation process, so that the skin can absorb the macromolecular components more easily and fully.
Owner:JUWENLEE (FUJIAN) COSMETICS CO LTD

A kind of hair care hair treatment ointment and preparation method thereof

The present application relates to the field of hair care products, and more specifically, it relates to a hair care hair-drying cream and a preparation method thereof. A hair care hair-drying cream comprises: 0.01-0.1% chelating agent, 0.1-2% thickener, 0.01-0.1% preservative, water; 4-8% cetearyl alcohol, 3-7% camellia oil, 0.1-0.5% behentrimethylammonium methyl sulfate, 1-3% isopropanol; 3-6% softener, 0.1-0.5% polyurethane-10, 0.01-0.1% pH adjuster; 0-0.001% colorant; its preparation method is: stir various raw materials of phase A / phase B to obtain phase A / phase B; emulsify phase A and phase B to obtain a mixture; add various raw materials of phase C and phase D to the mixture, stir evenly, and obtain a finished product. The hair care ointment provided in the present application has the excellent properties of being light, fast-absorbing, significantly repairing hair, and easy to rinse.
Owner:GUANGZHOU DAOXIN COSMETICS TECH CO LTD

Injectable long-acting collagen and preparation method and application thereof

PendingCN122251690Aprolong degradation timegood degradation timeProsthesisPolythylene glycolDrug biological activity
The application discloses injectable long-acting collagen and a preparation method and application thereof, and belongs to the technical field of collagen preparation. The application solves the problems of rapid degradation and insufficient mechanical property of collagen after injection into the body, and the problem of inability to have biological safety, good biological activity and injectability. The long-acting collagen is prepared by taking methoxypolyethylene glycol active ester and collagen as raw materials. Amide reaction is caused between the methoxypolyethylene glycol active ester and lysine residues on the collagen, hydrophilic PEG is introduced on the surface of the collagen, a hydration layer is formed, biological enzymes are hindered from contacting the collagen, collagen degradation is delayed, and the single-arm structure of the methoxypolyethylene glycol active ester can avoid product agglomeration and abnormal viscosity caused by excessive cross-linking. The long-acting collagen has a long retention time in the body, has no obvious cytotoxicity, has high biological safety, and maintains cell proliferation, migration and adhesion activity and biological repair functions.
Owner:JILIN CHUANGLI BIOTECHNOLOGY CO LTD

A moisturizing and whitening cream and preparation method thereof

The invention discloses a moisturizing and whitening cream and a preparation method thereof, aiming to provide a moisturizing and whitening cream which is mild and non-irritating, can inhibit or reduce melanin in all directions, accelerate skin metabolism, promote melanin shedding, reduce ultraviolet radiation, replenish moisture required by the skin, and can effectively improve microcirculation; the technical scheme thereof is: 1-10% oil, 2-8% polyol, 0.5-2% protease glucan, 0.2-2% mannan, 3-7% tocopherol, 2-5% cetearyl alcohol, 1-5% rice fermentation product filtrate, 0.5-1.2% black mulberry leaf extract, 1‑3% camellia leaf extract, 0.5‑1% plantain fruit extract, 0.1‑0.3% liquorice root extract, 0.2‑0.8% purslane extract, 0.2‑1% disodium cocoyl ethylenediamine PEG‑15 disulfate, 1‑2.5% soy lecithin, 0.5‑1.2% poloxamer, 0.1‑0.5% tetrasodium glutamate diacetate, 0.1‑0.3% allantoin, 0.1‑0.5% carbomer, 0.2‑1% dibutyl lauroyl glutamine, 0.5‑1% preservative, and appropriate amount of water; belonging to the technical field of cosmetics.
Owner:GUANGDONG ALICE COSMETICS CO LTD

Method for extracting elastin peptide from jellyfish

The invention relates to a method for extracting elastin peptide from jellyfish. The method comprises the following steps: S1, washing fresh jellyfish with clear water to remove impurities or soaking and salting the jellyfish with cold water containing citric acid / acetic acid to desalt; cutting into small blocks for later use; s2, mixing the jellyfish with a sodium hydroxide solution with the pH value of more than or equal to 11.5, carrying out pressure maintaining and shearing treatment by using a high-pressure shearing machine, centrifuging, and retaining precipitates; s3, mixing the precipitate with pure water, adjusting the pH value to be less than or equal to 1.5 by using hydrochloric acid, reacting for 1-4 hours, and centrifuging to reserve the precipitate; s4, the precipitate is mixed with sodium chloride saline water, the concentration of the sodium chloride saline water is 0.8-1.5 M, a reaction is conducted for 1-4 h, centrifugation is conducted, and the precipitate is reserved; s5, mixing the precipitate with pure water, adjusting the pH value to 6.8-7.4, adding elastinase for enzymolysis, performing high-speed centrifugation, and retaining the precipitate; and S6, collecting the precipitate to obtain the jellyfish elastin peptide. The jellyfish is used as a raw material and has the advantages in the aspects of raw material cost, availability, pretreatment and the like.
Owner:YUANHAI BIOTECH (DALIAN) CO LTD

Remodeling active peptide and preparation method thereof

The invention relates to the technical field of wrinkle resistance, in particular to a remodeling active peptide composition and a preparation method thereof. The skin care composition is prepared from acetyl hexapeptide-8, palmitoyl tripeptide, palmitoyl tetrapeptide-7, palmitoyl hexapeptide-12, sweet orange flower original liquid, a traditional Chinese medicine extract, a cubilose extract, golden camellia original liquid, an antioxidant, a humectant and a solvent according to the mass ratio of (1-3): (3-9): (4-7): (2-8): (2-4): (5-10): (0.5-1.5): (1-4): (1-3): (1-2): (3-15). The composition with an excellent anti-wrinkle effect is prepared by utilizing the coordination effect of the four small peptides with the anti-wrinkle effect and adding some traditional Chinese medicine extracts and plant original liquid, and after being used, the composition can be quickly absorbed by skin and further acts on the cellular level, so that the anti-wrinkle effect is achieved. According to the present invention, the skin care product has effects of skin whitening, skin whitening, skin whitening, skin whitening, skin whitening, skin whitening, collagen synthesis, fibronectin synthesis, glycosaminoglycan synthesis and eusuperficial cell regeneration promotion, skin cell elasticity and vitality recovery, and long-term use of the skin care product can relieve wrinkles and improve skin, and especially can significantly improve static wrinkles caused by skin inactivation such as nasolabial wrinkles, crow's feet and the like.
Owner:SHENZHEN ZHONGDAOMEI BIOTECHNOLOGY CO LTD