200 results about "Allyl amine" patented technology

Amine polymers, particularly aliphatic amine polymers, are useful in the treatment and prevention of bone disease and in methods for promoting bone formation. Sevelemer, polyallylamine crosslinked with epichlorohydrin, which is sold under the tradename Renagel®, is the preferred polymer used in the invention.

An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an additional antifungal compound. Another aspect of the invention is a method for treatment of a fungal infection of skin or nails comprising administering the antifungal composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

The invention discloses a method for preparing an anticoagulant vascular stent, which comprises the following steps of: A, depositing a plasma-polymerized allyl amine functional film on the surface of the vascular stent by using a pulse plasma polymerization method; B, preparing heparin sodium mixed solution; and C, precipitating heparin sodium, namely soaking the vascular stent on which the plasma-polymerized allyl amine functional film is deposited prepared in the step A into the heparin sodium mixed solution prepared in the step B, reacting at the temperature of between 4 and 20 DEG C for 12 to 48 hours, and after the reaction, fully rinsing by using distilled water, and drying to obtain the anticoagulant vascular stent. The vascular stent prepared by the method has the advantages of high binding force between an anticoagulant film layer on the surface of the vascular stent and the vascular stent, and excellent tissue compatibility and blood compatibility.

The invention discloses an amidated graphene oxide modified polycarboxylate superplasticizer. The main raw materials include: graphene oxide, methylallyl polyoxyethylene ether, acrylic acid, allyl amine, maleic anhydride, water, an oxidizing agent, a reducing agent, a condensation agent and an activating agent. The main method includes: firstly subjecting allyl amine and graphene oxide to amidation reaction to prepare allyl amine modified graphene oxide, then mixing the obtained allyl amine modified graphene oxide with methylallyl polyoxyethylene ether, acrylic acid and maleic anhydride, carrying out polymerization reaction under the initiation of the oxidizing agent and reducing agent, thus obtaining the amidated graphene oxide modified polycarboxylate superplasticizer. The method provided by the invention mainly utilizes the amidation reaction of allyl amine and graphene oxide to realize close combination of a graphene oxide two-dimensional nano lamellar structure with polycarboxylate superplasticizer molecules, so that graphene oxide can be better dispersed during application in concrete, and the synthesized superplasticizer product has more stable performance.

The invention discloses the preparation method of the ultra fine fiber membrane of an affinity acrylonitrile base copolymer. The acrylonitrile base copolymer is dissolved in solvent to form solution and then electrostatic spinning is conducted to prepare the fiber membrane. The mass percentage of the acrylonitrile base copolymer in the solution is two to eight percent; the spinning voltage of the electrostatic spinning is six to twenty five kv; the flow velocity of spinneret solution is 0.5 to 2.0 ml per hour with the deposition distance ranging from eight to twenty centimeters. The acrylonitrile base copolymer is acrylonitrile/allylamine copolymer, acrylonitrile/methyl allylamine copolymer, acrylonitrile/acrylamide copolymer or acrylonitrile/methacrylamide copolymer with the viscosity-average molecular weight being eighty to three hundred thousand; the solvent is one or various kinds which are mixed with random percentages of dimethyl sulfoxide, dimethyl formyl ammonia or dimethyl acetyl ammonia. After the glycan of the fixed shell of a chemical bond at the surface of the membrane, the membrane is used for separating and purify protein with simple operation, good chemical stability and low cost.

The invention relates to a method for preparing side-chain modified polysiloxane. The method comprises the following steps: (1) uniformly mixing dichlorohydrosilane with an organic solvent, dropping crylic acid or allyl alcohol or allyl amine into the mixed solution in ice bath, stirring to implement a reaction, after the reaction is completed, and performing vacuum distillation to remove the organic solvent so as to obtain a chlorosilane substituted product; (2) putting the chlorosilane substituted product and a catalyst into a solvent, performing a reaction for 4-20 hours at 30-90 DEG C, performing vacuum distillation to remove the organic solvent so as to obtain a silicon-hydrogen addition product; (3) performing co-hydrolysis on the silicon-hydrogen addition product with alkoxy silane or chlorosilane of bifunctionality, adding a proper amount of an end-capping reagent, and performing catalysis balance reaction, thereby obtaining side-chain modified polysiloxane. The raw methods are cheap and easy to obtain, the product yield is high, operation steps are simple and convenient, tedious steps of protection, deprotection and the like are not needed, and industrialization is easy to achieve.

The invention discloses a release mass transfer rate adjustable and controllable intelligent drug delivery carrier, which is a hollow spherical microcapsule. A membrane of the microcapsule mainly comprises poly[methacrylic-N, N-dimethylamino ethyl ester], super-paramagnetic Fe3O4 nanoparticles and poly(N-isopropyl acrylamide) temperature-sensitive sub-microspheres or poly[N-isopropyl acrylamide-copoly-acrylamide-copoly-allyl amine] temperature-sensitive sub-microspheres. A process for preparing the drug delivery carrier comprises the following steps of: (1) preparing the temperature-sensitivesub-microspheres; (2) preparing modified super-paramagnetic Fe3O4 magnetic fluid; (3) preparing intermediate phase fluid, inner phase fluid and outer phase fluid; and (4) preparing the drug delivery carrier.

Provided is an industrially advantageous process for producing allylamine polymers from various allylamines in an organic solvent with ease and at high yields, and the process comprises polymerizing allylamines in a medium containing an organic solvent in the presence of an azo compound selected from azo compounds of the formulae (I) and (II),wherein symbols are as defined in the specification.

The invention discloses a polycarboxylate superplasticizer with super high early strength and a preparation method of the polycarboxylate superplasticizer. The polycarboxylate superplasticizer is prepared as follows: amine polyoxyethylene ether, acrylic acid, maleic hydroxy acid ester and allyl amine are taken as monomers and added with an inorganic peroxide initiator for free radical copolymerization, main chains of molecules of the superplasticizer contain carboxylic acid groups, sulfonic acid groups and amino groups simultaneously, side chains adopt long-chain polyamine ether, and the ratio of polyoxyethylene ether to acrylic acid to water to maleic hydroxy acid ester to allyl amine to the inorganic peroxide initiator in parts by mass is 100:(20-30):(100-150):(2-10):(2-10):(0.1-0.5). The invention further provides the preparation method of the polycarboxylate superplasticizer. The polycarboxylate superplasticizer with super high early strength has the advantages of short setting time, high early strength, good adaptability, extremely low chlorine ion content and capability of improvement of the concrete durability; meanwhile, the production process is simple, low in cost, environment-friendly and pollution-free, and mass production can be realized.

The invention relates to a method for preparing a 2-oxazolinone compound containing a trifluoromethyl group from an allyl amine compound in virtue of carbon dioxide. Specifically, the allyl amine compound as shown in a formula 1 which is described in the specification reacts with CO2 in a solvent in the presence of a copper catalyst, alkali and a trifluoromethylation reagent so as to prepare the 2-oxazolinone compound as shown in a formula 2 which is described in the specification. In the formula 2, R<1>, R<2>, R<4> and R<5> are independently selected from a group consisting of H, halogen, a cyano group, an alkyl group, a carbonyl group, an ester group, an aryl group, a heteroaryl group and the like, R4 or R5 can optionally form a ring with R1, and the alkyl group, the carbonyl group, the ester group, the aryl group and the heteroaryl group can be optionally substituted by halogen, the alkyl group or the like; and R3 is H, halogen, an alkyl group, an aryl group, or the like.

This invention relates to the surface modified silica by plasma polymerization coating, plasma polymerization method and plasma polymerization devices. Silica, active ingredients of EMC, is coated by plasma polymerization coating in order to enhance the adhesion of silica to epoxy resin and thus to improve the reliability of EMC. The monomers for the plasma polymerization coating were 1,3-diaminopropane, allylamine, pyrrole, 1,2-epoxy-5-hexene, allylmercaptan and allylalcohol, and the surface modified silica was utilized to prepare EMC for electronic devices. The plasma polymerization coating, which is known to be environment-friendly method, provided excellent flexural properties of EMC compared to the conventionally prepared EMC.

The present invention provides a preparing method of accelerating transmitting film containing poly allyl amine for separating acidic gas. The invention includes following steps: pretreatment using polysulphone or polyether sulfone plate film as base film; preparing casting film solution by mixing poly allyl amine solution with polyvinyl alcohol solution, plasmosan solution and polyacrylamide solution respectively, casting film solution coating on the base film; accelerating transmitting film containing poly allyl amine for separating acidic gas being obtained by dyring. The method has a simple process, the accelerating transmitting film has a better filming performance and pressure resistance, the mainly parameter is CO2/CH4, CO2/N2 separating factor 40-150, CO2 permeation rate (10-150) *10-6cm3(STP)cm-2s-1cmHg-1; H2S/CH4 separating factor 60-500, H2S permeation rate (50-900) *10-6cm3(STP)cm-2s-1cmHg-1.

A new method for the preparation of aminopropyl terminated or internal functionalized polyalkyl or aryl siloxanes is described. The method involves readily available commercial starting materials and proceeds under mild conditions in high yield. Purification is facilitated over present commercial procedures and a wider variety of internal functionalized siloxanes may be prepared. The method involves hydrosilation of commercially availably alkyl or aryl functional hydrosilicones with allyl amine or other alkenyl or arenyl amine in the presence of platinum (0) divinyltetramethylsiloxane or platinum (0) cyclovinyl complexes.

Pressure sensitive adhesive compositions having enhanced resistance to water-whitening comprising an aqueous emulsion polymer are disclosed. The polymer comprises the polymerization reaction product of a polymerizable aqueous emulsion comprising: (i) a hydrophobic monomer mixture of at least one alkyl acrylate or alkyl methacrylate ester of an alcohol wherein the alkyl portion of the alcohol is linear or branched and contains at least 4 carbon atoms, and at least one styrenic monomer, wherein the styrenic monomer is up to about 30 wt. % of the total hydrophobic monomer mixture, (ii) at least about 1 wt. % of at least one hydrophilic monomer, (iii) at least about 5 wt. % of at least one partially hydrophilic monomer selected from alkyl acrylate or alkyl methacrylate esters of an alcohol wherein the alkyl portion of the alcohol has 1 to 2 carbon atoms, N-vinyl-2-pyrrolidone, or mixtures thererof, and (iv) a water-soluble or water-dispersible polymerizable surfactant selected from compounds having a terminal allyl amine moiety, polyoxyalkylene-1-(allyloxymethyl)alkyl ether sulfate salts, or mixtures thereof, and the average particle size of the polymer is less than or equal to 200 nm. Also disclosed are processes for preparing same.

The invention discloses an organosilicone modified isocyanate prepolymer for solvent-free type synthetic leather and a preparation method thereof. The prepolymer contains a compound in the structure shown in the description, wherein R is aryl or fatty group; a and b are natural numbers. The preparation method comprises the following steps that (1) octamethylcyclotetrasiloxane, 2,4,6,8-tetramethyl-2,4,6,8-tetraphenylcyclotetrasiloxane and acid catalysts are added into a reactor; then, tetramethyl dihydrodisiloxane is added; ring-opening polymerization reaction is performed for 4 to 6h at 60 to80 DEG C; temperature reduction, neutralization, water washing, filtering and micromolecule by-product removal are performed to obtain hydrogen-terminated blocking methyl phenyl polysiloxane; (2) thehydrogen-terminated methyl phenyl polysiloxane obtained in the step (1) and allyl amine react under H2PtCl6 catalysts to prepare hydrogen-terminated blocking methyl phenyl polysiloxane; (3) the product in the step (2) is dehydrated and then reacts with isocyanate monomers to generate the prepolymer with the terminal group being NCO.

The invention relates to a method for synthesizing clethodim, in particular to a process for synthesizing an agricultural herbicide clethodim, namely (+/-)-2-[(E)-3-chloro-allyloxyimino]propyl-5-[2-(ethylthio)propyl]-3-hydroxy-cyclohexyl-2-keten. The method uses petroleum ether as a solvent and a ketone complex as a stabilizing agent to perform condensation reaction on propyl-triketone and allyl amine oxide to prepare the clethodim. Under the condition that the ketone complex serves as the stabilizing agent, the method can perform the condensation reaction at a low temperature by using the petroleum ether as the solvent, and prevent the clethodim product obtained through the reaction from being decomposed due to a high temperature to cause yield declination and content to decrease, thus the yield of the method can reach about 97 percent and the content reaches 94 percent.

The invention discloses a preparation method of 2,3,5-trimethyl hydroquinone diester. According to the preparation method, oxo-isophorone and acetic anhydride carry out rearrangement and acylation under the catalytic action of a modified cyclodextrin supported solid acid to prepare 2,3,5-trimethyl hydroquinone diester. The solid acid is loaded on poly(allyl amine) modified methyl-beta-cyclodextrin; the reaction conditions are mild, the oxo-isophorone conversion rate and the product selectivity are high, the catalyst can be repeatedly used, and the shortages of a conventional preparation technology such as bad selectivity, severe equipment corrosion, complicated operation, and the like, are overcome.

The present invention is directed to an adhesion promoter for bonding fluoropolymers and, more specifically, for bonding a fluoroplastic layer to a fluroelastomer layer in a multi-layered article, such as a fuel filler hose. In one embodiment, the adhesion promoter includes a solvent, a polyallyamine (PAA), and an organo-onium compound. The solvent can include an organic solvent, such as an alcohol, e.g., methanol, ethanol, or isopropanol. The polyallylamine includes a homopolymer of 2-propen-1-amine, and the organo-onium compound can include an organic phosphonium salt. The final composition of the adhesion promoter can include solvent in the range of about 80% by weight to about 99% by weight; polyallylamine in the range of about 0.5% by weight to about 10% by weight; and organo-onium compound in the range of about 0.5% by weight to about 10% by weight. Such adhesion promoter may further optionally include a silane, such as an organosilane.