497 results about "Carbene" patented technology

The invention relates to a decarboxylation coupling method catalyzed by N-heterocyclic carbene. Small organic molecule N-heterocyclic carbene is used as an organic catalyst, manganese is used as a reducing agent, aromatic acid or derivatives thereof and an electrophilic reagent are subjected to cross coupling, and multi-structure ketone is prepared. Small organic molecule N-heterocyclic carbene is used as an organic catalyst, manganese is combined as a reducing agent, cross coupling of aromatic acid or derivatives thereof and some cheap and easily available electrophilic reagents can be promoted, ketones with various structures can be provided at high yield, and the method is especially suitable for preparation of high-steric-hindrance ketone compounds and has wide application prospects. The method has the advantages of high yield, convenience in separation, high efficiency, mildness, low-cost economy and high industrial application value, and the requirement on transition metal catalysis can be reduced.

The invention relates to a method for synthesizing 1, 2-allene ketone, and discloses a method for synthesizing 1, 2-allene ketone by taking eneyne, 1, 4-dihydropyridine and benzoyl fluoride as substrates, 2, 4, 5, 6-tetra (diphenylamino)-isophthalonitrile as a photocatalyst, 5, 6, 7, 8-tetrahydro-3-(2, 6-diisopropyl phenyl)-4H-cycloheptyl thiazole perchlorate as N-heterocyclic carbene, cesium carbonate as alkali and acetonitrile as a solvent through a one-pot method. And reacting at room temperature for 4 hours under visible light of 12W and 460nm LED blue light to obtain allene ketone. The reaction conditions are mild, and the method has good functional group tolerance.

The invention discloses a synthesis method of a 9, 9-di-n-octylfluorene copolymer, which comprises the following steps: under the action of an N-heterocyclic carbene palladium complex and organic alkali, reacting 9, 9-dioctylfluorene-2, 7-bis (boronic acid pinacol ester) with 2, 5-dichloropyridine to obtain the 9, 9-di-n-octylfluorene copolymer, and reacting the 9, 9-di-n-octylfluorene copolymer with the boronic acid pinacol ester to obtain the 9, 9-di-n-octylfluorene copolymer. The structure of the N-heterocyclic carbene palladium complex is as shown in a formula (I): # imgabs0 # formula (I); the 9, 9-di-n-octylfluorene copolymer is prepared through catalysis of the N-heterocyclic carbene palladium complex, the 9, 9-di-n-octylfluorene copolymer has the advantage of being high in catalysis efficiency, the 9, 9-di-n-octylfluorene copolymer with high molecular weight and narrow distribution can be obtained, and the problems that a phosphine ligand catalyst is large in toxicity and the like are solved; and the application of the 9, 9-di-n-octylfluorene copolymer in preparation of a hole transport layer of a perovskite solar cell is developed.

The invention belongs to the field of fine chemical engineering, and particularly relates to an N-heterocyclic carbene complex catalyst and application of the N-heterocyclic carbene complex catalyst in pipelined continuous synthesis of a silane coupling agent. The invention provides an N-heterocyclic carbene complex catalyst, which comprises a ligand and an active component, the ligand is an N-heterocyclic carbene ligand, and the active component is a transition metal; the molar ratio of the N-heterocyclic carbene ligand to the transition metal is 1: 1. The invention also provides a method for pipelined continuous synthesis of the silane coupling agent, which comprises the following steps: carrying out homogeneous hydrosilylation reaction in a pipelined reactor by taking hydrogen-containing silane and unsaturated hydrocarbon as raw materials in the presence of an N-heterocyclic carbene complex catalyst to obtain the silane coupling agent. The spatial configuration and the electronic property of the N-heterocyclic carbene ligand precursor are designed and regulated, so that the N-heterocyclic carbene ligand precursor is matched with transition metal, and the N-heterocyclic carbene ligand precursor can be applied to hydrosilylation reaction.

The invention belongs to the technical field of textile production, and relates to an active disperse dye and a dyeing process. The reactive disperse dye comprises a dye matrix and a bis-aziridine chain segment grafted on the dye matrix, and-OCH2-is introduced to an aromatic ring para-position of the bis-aziridine chain segment as an electron-donating group. A dyeing process: after active disperse dye is dissolved, dyeing the textile; the textile consists of more than one of natural fibers and synthetic fibers; the dyeing temperature is 85-100 DEG C, and the dyeing temperature is higher than Tg of the synthetic fibers. According to the invention, a '-OCH2-' electron-donating group is introduced in the para-position of an aromatic ring of a diaziridine chain segment, and the conjugation effect and the induction effect of the group reduce the activation energy of C-N bond breakage, so that carbene can be efficiently generated without depending on a high-temperature or acid-base environment; the problems that in the prior art, the condition for generating carbene through a diaziridine chain segment is harsh, and the color fastness of the dyed textile is low when supercritical CO2 fluid is adopted for dyeing are solved.

The invention relates to a nitrogen-containing heterocyclic compound as well as a preparation method and application thereof, belongs to the technical field of heterocyclic compound synthesis, and solves the problems of low reaction efficiency and high energy consumption caused by the fact that an existing method for synthesizing an indole maleimide derivative needs to be carried out step by step. The preparation method comprises the following steps: step 1, adding indoleacetamide and a nucleophilic reagent into a mixed solution, and reacting; 2, performing post-treatment to obtain a nitrogen-containing heterocyclic compound; the mixed solution comprises alkali, an additive and an organic solvent; the alkali comprises one of triethylamine (Et3N), N, N-diisopropylethylamine, pyridine and 1, 8-diazabicyclo [5.4. 0] undec-7-ene, and the alkali comprises one of 1, 8-diazabicyclo [5.4. 0] undec-7-ene.

The invention provides a continuous production method and device for long-chain alkyl phenyl modified silicone oil with accurate and controllable viscosity. The continuous production method of the long-chain alkyl phenyl modified silicone oil is characterized by comprising the following steps: step 1, reacting hydrogen-containing silicone oil and a styrene monomer in a microchannel reactor to obtain a first reactant; and step 2, further reacting the first reactant with long-chain carbene in a dynamic tubular reactor to obtain the long-chain alkyl phenyl modified silicone oil.

The invention discloses a 9, 9-di-n-octylfluorene copolymer as well as a preparation method and application thereof, the structure of the 9, 9-di-n-octylfluorene copolymer is shown as a formula (I): # imgabs0 # formula (I), the number-average molecular weight Mn of the 9, 9-di-n-octylfluorene copolymer is 18.6-27.2 kDa, and the molecular weight distribution PDI is 1.9-3.0; the 9, 9-di-n-octylfluorene copolymer provided by the invention is used for preparing a perovskite solar cell, and is beneficial to improving Voc, Jsc and FF values of the perovskite solar cell, so that the PCE value of the perovskite solar cell is improved; the 9, 9-di-n-octylfluorene copolymer is prepared through catalysis of the N-heterocyclic carbene palladium complex, the 9, 9-di-n-octylfluorene copolymer has the advantage of being high in catalysis efficiency, the 9, 9-di-n-octylfluorene copolymer with high molecular weight and narrow distribution can be obtained, and the problems that a phosphine ligand catalyst is large in toxicity and the like are solved.

The invention belongs to the technical field of organic synthesis and carbene catalysts, and particularly relates to a bridged double-center carbene catalyst ligand as well as a preparation method and application thereof. The structure of the bridged double-center carbene catalyst ligand is as shown in a formula I: # imgabs0 #, in the formula I, R1, R3, R4, R5, R6, R7, R8, R9 and R10 are respectively and independently selected from any one of H, i-Pr, CH3, Cl, F and NC; n is equal to 1-9; n is selected from any one of Cl and Br. Compared with a carbene catalyst ligand used in the past, the bridged double-center carbene catalyst ligand provided by the invention has double active centers, so that the double-center carbene catalyst ligand can be used for preparing the double-active-center carbene catalyst ligand, and the double-active-center carbene catalyst ligand can be used for preparing the double-active-center carbene catalyst ligand; and by carrying out ligand exchange with a carbene catalyst precursor with a single active center, the active center can be aggregated, so that the high-activity carbene catalyst with double centers is obtained, and higher reaction activity and atom economy are achieved.

Disclosed herein is a compound according to formula Ia: Also disclosed herein are a pharmaceutical composition comprising the compound as aforementioned, use of the compound as aforementioned, a method of treating one or both of a microbial and a fungal infection comprising the step of administering a pharmaceutically effective amount of the compound as aforementioned or the pharmaceutical composition as aforementioned, and an antimicrobial and / or antifungal detergent composition comprising the compound as aforementioned, and a surfactant.

The invention relates to a synthesis method of a diunsaturated ester compound catalyzed by N-heterocyclic carbene, and belongs to the field of organic synthesis. According to the preparation method, the synergistic effect of N-heterocyclic carbene and light is utilized, gamma-oxo unsaturated aldehyde and Katritzky salt are taken as starting raw materials, the Katritzky salt generates alpha-ester free radicals through a single electron transfer process under the illumination condition, the free radicals react with a nucleophilic trienol intermediate generated through catalysis of the N-heterocyclic carbene, and the alpha-ester free radicals react with the nucleophilic trienol intermediate to generate the gamma-oxo unsaturated aldehyde. Target products are obtained with good yield and high regioselectivity, so that a series of epsilon-alkylated diunsaturated ester compounds are efficiently synthesized. The method is simple and convenient to operate, green and efficient, has the advantages of no transition metal participation, wide substrate applicability and the like, provides a new way for synthesis of the diunsaturated ester compound, and has a wide application prospect.

The present invention provides: a silicone compound which is compatible with a hydrophilic monomer; and a composition for contact lenses, the composition being capable of forming a transparent polymer.　The composition for contact lenses contains a compound represented by formula (1). In formula (1), n represents an integer of 0 to 300, R1, R2, R3, R4, R5, R6, R7, and R8 each independently represent a hydrogen atom or an alkyl group having 1 to 30 carbon atoms, R9 and R10 each independently represent a hydrogen atom or a methyl group, and X1, X2, X3, and X4 each independently represent an alkylene group having 1 to 20 carbon atoms.

The present invention provides: a silicone compound that is compatible with a polymerizable monomer; and a copolymer of said silicone compound and a polymerizable monomer.　This silicone-containing copolymer is obtained through polymerization of a composition containing a polymerizable monomer and a compound represented by formula (1).　In formula (1), n represents an integer of 0-300, R1, R2, R3, R4, R5, R6, R7, and R8 each independently represent hydrogen or alkyl having 1-30 carbon atoms, R9 and R10 each independently represent hydrogen or methyl, and X1, X2, X3, and X4 each independently represent alkylene having 1-20 carbon atoms.

The invention relates to the field of olefin oligomerization reaction, and discloses a low-carbon olefin oligomerization reaction method. The invention relates to a low-carbon olefin oligomerization reaction method. The method comprises the following step: carrying out contact reaction on a mixture containing low-carbon olefin and a diluent and a solid acid catalyst, the solid acid catalyst is a supported MWW molecular sieve, and the supported MWW molecular sieve comprises an active metal and an MWW molecular sieve; wherein the ratio of the pyridine infrared L acid amount of the supported MWW molecular sieve to the total acid amount is (0.4-0.9): 1; the pyridine infrared spectrum of the supported MWW molecular sieve has two L acid absorption peaks at 1430-1473cm <-1 >, and the ratio of the absorption peak area of the L acid at the front wave number position to the total area of the two L acid absorption peaks is (0.3-0.7): 1. According to the method, the low-carbon olefin oligomerization reaction is catalyzed by selecting the catalyst with specific acid amount, so that the conversion rate of reaction raw materials and the selectivity of a target product are improved.

The invention belongs to the field of organic synthesis, and particularly relates to an efficient method for preparing ethyl chrysanthemate by using a Beta / CuCl nano molecular sieve catalyst. Glycine ethyl ester hydrochloride and sodium nitrite react in a heptane solvent to generate ethyl diazoacetate, and then ethyl diazoacetate reacts with octa-carbene to generate ethyl chrysanthemumate. The catalyst provides an acidic environment and active sites, promotes generation of diazo compounds, controls reactant diffusion through a pore channel structure, and improves the reaction rate and selectivity. The catalyst stabilizes the carbene intermediate and reduces the reaction temperature. The catalyst can be recycled, and environmental pollution and cost are reduced. The yield of the ethyl chrysanthemate exceeds 98%, the yield and quality are improved, and a new scheme is provided for the sanitary insecticide and pharmaceutical industry.

The invention discloses an N-heterocyclic carbene compound and an application thereof. The invention provides a compound as shown in a formula I. The N-heterocyclic carbene compound disclosed by the invention is novel in structure and has a good application prospect in a monovalent copper catalyzed silylation reaction. # imgabs0 #

Luminescent homometallic and heterometallic nanoclusters that include ditopic ligands with at least one N-heterocyclic carbene are presented. High photoluminescence quantum yields are reported, including one at 68%. These nanoclusters are thermally stable and are suitable for imaging, as photosensitizers, photosensors, and for photodynamic or X- ray photodynamic therapy..

The invention discloses a mechanochemical synthesis method of an N-heterocyclic carbene metal assembly, and relates to the technical field of chemical synthesis. The method comprises the following steps: mixing N-heterocyclic carbene precursor salt, silver oxide and alkali, adding grinding balls, and carrying out ball milling; and dissolving in a solvent, centrifuging, concentrating under reduced pressure, adding into a precipitant, centrifuging and drying in vacuum to obtain the N-heterocyclic carbene metal assembly. The method is used for synthesizing various types of metal supramolecular assemblies through one-pot ball milling under the condition of no solvent at the ambient temperature, and is carried out under the condition that the method is simpler and milder than other synthesis processes, and the yield is higher. Compared with harsh reaction conditions of a solution method, the solid ball milling method is simple and convenient to operate and rapid in reaction, and generation of by-products formed by AgI ions and a polar solvent is avoided. The problems that in the prior art, the reaction condition for preparing the N-heterocyclic carbene metal assembly is harsh, and by-products are likely to be generated are solved.

The invention relates to a solid adsorbent and a preparation method thereof. The solid adsorbent is composed of a porous solid carrier and a load. The porous solid carrier comprises a molecular sieve, silica gel, aluminum oxide, hydrotalcite and derivatives thereof. The load is composed of a main agent and an auxiliary agent, the main agent is polyamide-amine of which the terminal group is modified by amino and hydroxyl, and the molar ratio of the amino to the hydroxyl is 1: 1-1: 1.5; and the auxiliary agent is one or more of AMP (adenosine monophosphate), hydroxyethylpiperazine (HPZ), 1, 8-diazabicyclo undec-7-ene (DBU) and sulfolane (TS). The load accounts for 25%-150% of the weight of the porous solid carrier, and the mass fraction of the main agent in the load is 35%-80%. The method has the advantages of adjustable selectivity, high adsorption speed, large adsorption capacity and high removal rate of COS, methyl mercaptan, ethanethiol and other organic sulfur.

To provide a tetradentate cyclometallized platinum (II) complex, an electronic device, and applications thereof.SOLUTION: The present invention belongs to a technical field of organic electroluminescence, and particularly relates to a tetradentate cyclometallized platinum (II) complex, an electronic device, and applications thereof. In the present invention, by introducing a 2,6-di(phenyl)tert-butylphenyl at an appropriate position of a ligand, a dihedral angle between pyridine units is increased, and the stacking between molecules is reduced. At the same time, the charge distribution of an excited state is improved, the excited state of a material is made to have a charge transfer state from more metals to the pyridocarbene so as to prolong a device lifetime, and it is easy to produce an evaporated OLED device having excellent chemical and thermal stability. After being combined with a fluorescent doping material, the transport of holes and electrons is balanced, and an energy transfer between a host and a guest is made to be more efficient. When used as an organic electroluminescent device, the current efficiency and the lifetime are significantly improved, and a turn-on voltage is significantly reduced. It is expected to be widely applied to the fields of OLED display and lighting.SELECTED DRAWING: None

The invention discloses a tetracyclododecene preparation method, which comprises: mixing an N-methyl pyrrolidone (NMP) solvent, norbornene and toluene, heating to a reaction temperature in a reaction kettle, dropwise adding cyclopentadiene, and carrying out a Diels-Alder reaction in the reaction kettle to prepare tetracyclododecene, the high-purity tetracyclododecene with the mass content of 99% or above can be obtained through subsequent rectification. According to the process, cyclopentadiene is dropwise added, so that the reaction time is shortened, side reactions are reduced, the reaction is carried out in a liquid phase by taking NMP (N-Methyl Pyrrolidone) with a higher boiling point as a solvent, the reaction temperature can be reduced, the reaction process can be carried out at normal pressure, the production safety is improved, and the production operation cost is reduced.

The invention discloses a synthesis method of 3 ', 4', 5 '-trifluoro-o-aminobiphenyl, and belongs to the technical field of synthesis of pesticide bactericides, aryl o-amino halide and 3', 4 ', 5'-trifluorophenylboronic acid are used as raw materials, imidazole type N-heterocyclic carbene is used as a ligand, Suzuki coupling reaction is performed in a solvent under the protection atmosphere and the catalytic action of PdCl2 through a one-pot method, and the 3 ', 4', 5 '-trifluoro-o-aminobiphenyl is obtained. According to the method, aryl o-amino halide and 3 ', 4', 5 '-trifluorophenylboronic acid are coupled to obtain 3', 4 ', 5'-trifluoro-o-aminobiphenyl, and 3 ', 4', 5 '-trifluoro-o-aminobiphenyl is obtained. The method provided by the invention has the advantages of low catalyst dosage, low cost and cheap and easily available raw materials, successfully solves the problem of industrial synthesis of 3 ', 4', 5 '-trifluoro-o-aminobiphenyl, and has the advantages of simplicity in operation and easiness in large-scale production.

The present invention discloses a photocatalyst for the regeneration of coenzyme NADH and a preparation method thereof, wherein the photocatalyst is a donor-π-acceptor type conjugated organic polymer, with a triazine-based ligand as an acceptor unit and a heterocyclic ligand as a donor unit, wherein the molar ratio of the triazine-based ligand to the heterocyclic ligand is 1:(1-2), the triazine-based ligand raw material selects 2,4,6-trimethyl-1,3,5-triazine, and the heterocyclic ligand raw material selects a heterocyclic diformaldehyde containing a furan or thiophene structure. The photocatalyst is prepared by a solvothermal method through a Knoevenagel aldol condensation reaction, the reaction solvent selects a mixed solvent of n-butanol and o-dichlorobenzene or a mixed solvent of mesitylene and 1,4-dioxane, and the catalyst used in the reaction selects at least one of trifluoroacetic acid, potassium hydroxide, 1,8-diazabicycloundecane-7-ene, sodium hydroxide, and cesium carbonate. The developed photocatalyst has a donor-π-acceptor type conjugated structure, and has high catalytic activity, high selectivity, good stability, and easy separation and recovery for the regeneration of coenzyme NADH.

Methods of selectively depositing a passivation layer on a metal surface of a semiconductor substrate are described. Exemplary methods may include exposing the semiconductor substrate having a metal surface and a non-metal surface to a first precursor to form a first portion of the passivation layer on the metal surface, the first precursor including an isonitrile. The exemplary methods may further include exposing the semiconductor substrate comprising a metal surface and a non-metal surface to a second precursor to form the passivation layer on the metal surface. The second precursor may include an amine, an alcohol, or a thiol.

The present invention provides a material comprising (i) a crown ether of formula (I), (ii) a crown ether of formula (II), and / or (iii) a crown ether of formula (III), or a salt thereof, wherein each m is independently an integer from 1 to 8, p is an integer from 1 to 1000, each "(F)" represents an optional bond and / or structure, each X is an optional substituent, and each * independently represent -H, =O, or a bond to the remainder of the substance, provided that at least one * is the bond to the remainder of the material, and the remainder of the material is attached via an sp3-sp3 carbon-carbon bond, methods of making the material, and methods of using the material are provided. [Formula 1] JPEG2025535965000092.jpg69149

The present disclosure provides a latent catalyst for use in two-component crosslinkable coating systems, and preferably two-component Michael addition chemistry. The latent catalyst is a salt having a structure of BR+A- wherein BR+ has a structure configured, in one approach, to be deprotonated forming a carbene with the B moiety thereof including a 5-, 6-, or 7-membered heterocycle including two or more heteroatoms with an intermediate carbon atom and R thereof represents one or more substituents on the heterocyclic ring and selected from hydrogen or a substituted or unsubstituted alkyl, vinyl, aryl, alkaryl group, hydrocarbyl group, or combinations thereof. The A- moiety may be a carbonate anion, a bicarbonate anion, or a carbamate anion.

The present invention relates to cationic molybdenum and tungsten complexes containing a heterocyclic nitrogen carbene (NHC) and preferably a halogen-containing aryloxy ligand. The catalysts are active in olefin metathesis reactions and provide for E-selectivity.

The present application relates to a kind of ionic nitrogen heterocyclic carbene covalent organic framework and its preparation method and application, the ionic nitrogen heterocyclic carbene covalent organic framework with amine monomer, aldehyde monomer and vinyl ionic liquid as raw material, by one-pot method, it is prepared by povalorov reaction.The ionic nitrogen heterocyclic carbene covalent organic framework prepared in the present application can be used for the deuterium reaction of a variety of aromatic aldehyde, heterocyclic aldehyde and multi-site substituted aldehyde substrate as catalyst, with high catalytic activity and recyclable performance.

The invention relates to a method for preparing a boronized carbonyl derivative by catalyzing an alpha, beta-unsaturated carbonyl derivative with a heterogeneous photocatalyst, which comprises the following steps: by taking the alpha, beta-unsaturated carbonyl derivative and N-heterocyclic carbene borane as raw materials and cadmium sulfide as the heterogeneous photocatalyst, reacting for 1-100 hours at 0-80 DEG C in an inert atmosphere and under the illumination condition, thereby obtaining the boronized carbonyl derivative. The product borylated carbonyl derivative is obtained. The alpha-boron substituted compound is prepared by adopting the heterogeneous photocatalyst for the first time, the reaction condition is mild, and the catalyst can be recycled.

To provide means to produce glycolaldehyde dialkyl acetal in high yield.SOLUTION: A production method includes a glycolaldehyde formation step of converting paraformaldehyde to glycolaldehyde in an ether type solvent in the presence of an N-heterocyclic carbene catalyst, and an acetalization step of treating the glycolaldehyde with an alcohol solution of hydrogen chloride to obtain glycolaldehyde dialkyl acetal. The glycolaldehyde formation step and the acetalization step are performed in a single container.SELECTED DRAWING: None