14 results about "Imidazolidines" patented technology

The invention provides a one-pot synthesis method of 1, 3-dimethyl-2-imidazolidinone, which comprises the following steps: mixing a basic catalyst, an ionic liquid and methanol, adding ethylenediamine to synthesize 2-imidazolidinone under a low-temperature condition, and raising the temperature to enable the 2-imidazolidinone and dimethyl carbonate to have an N-methylation reaction. According to the synthesis method, the ionic liquid is adopted as the catalyst, on one hand, the ionic liquid serves as a phase transfer catalyst, and the acid binding effect of the acid binding agent is enhanced; on the other hand, as a carbene catalyst, dimethyl carbonate is activated, so that the acylation and methylation reaction efficiency is improved.

The utility model discloses drying and screening integrated equipment for 2-imidazolidinone production, and relates to the technical field of drying and screening equipment, the drying and screening integrated equipment comprises a supporting frame, a drying box and a box cover, a rotatable placing plate is installed in the drying box, a first motor is fixedly installed on the outer wall of the drying box, and a second motor is fixedly installed on the outer wall of the drying box. The first motor is in transmission connection with the containing plate, the lower portion of the drying box is fixedly connected to a material guiding groove which is in a funnel shape on the whole, a guiding cylinder is fixedly connected to the bottom of the material guiding groove, screening holes are formed in the bottom of the inner wall of the guiding cylinder, and a rotatable supporting frame is installed on the inner wall of the guiding cylinder. According to the device, the drying box is arranged above the guide cylinder, the screening holes are formed in the outer wall of the guide cylinder, and the rotatable feeding auger is installed in the guide cylinder, so that the device can quickly transfer materials into the guide cylinder to be screened after completing drying of the materials, manual interference of transferring is not needed, and the drying efficiency is improved. And the materials are prevented from being polluted in the transferring process.

The present application provides a kind of big granule glue for diaphragm, diaphragm coating slurry, diaphragm and battery, the big granule glue is copolymer, the copolymer includes: aromatic ethylene structural unit;Acrylate structural unit;Crosslinking structural unit, the side chain of the crosslinking structural unit contains reactive functional group, the reactive functional group includes one or more of epoxy group, isocyanate group, siloxane group, hydroxyl group, amino group, carboxyl group and unsaturated hydrocarbon group;And acrylamide structural unit, the acrylamide structural unit contains imidazolidinone group, to overcome the problem that existing ceramic diaphragm exists high battery impedance and insufficient rate performance.

This invention relates to a method for preparing imidazoline derivatives using heterogeneous catalysis. The invention addresses the technical problem that existing methods for synthesizing imidazoline derivatives require transition metal catalysis and involve cumbersome reaction processes. The method comprises: 1. Preparing a photocatalyst using melamine and glyoxal; 2. Preparing the imidazoline derivative under blue LED light. This invention provides a simple one-step method for synthesizing imidazolines and their derivatives, using heterogeneous materials as photocatalysts. This method eliminates cumbersome synthesis steps, achieves high yields, and is environmentally friendly. The reaction can be carried out at room temperature and pressure under mild conditions, requires no transition metal catalysis, and achieves a yield of over 40%. It has advantages such as simple operation, safety, environmental friendliness, and low cost. This invention is used for the preparation of imidazoline derivatives.

The invention discloses a low-density high-resilience polyurethane foam packaging material and a preparation method thereof, and relates to a light-weight high-resilience packaging material and a preparation method thereof. The low-density high-resilience polyurethane foam packaging material is suitable for packaging instruments, equipment and the like. The foaming material is formed by foaming a prepolymer C and a composite material, the prepolymer C is prepared from isophorone diisocyanate, a modifier B, imidazolidinyl urea, isobornyl acrylate and hydroxyethyl acrylate through a reaction; the modifier B is prepared from xylene, terephthalaldehyde and ethanolamine through a reaction; the combined material D is prepared by mixing polyether polyol E and F, polyester polyol, polyethylene glycol adipate, a foam stabilizer, water, cyclopentane, triethylene diamine (33% aqueous solution), stannous octoate and a modifier A; the modifier A is prepared by mixing and reacting a water phase consisting of water, nano silicon dioxide, polyvinylpyrrolidone and sodium chloride with an oil phase consisting of a polymeric monomer, low-boiling-point saturated hydrocarbon and azodiisobutyronitrile. The high-elasticity and impact-resistant rubber material is good in buffering and impact-resistant performance and rebound resilience, low in density, light in weight and environment-friendly.

The application provides a preparation method, special equipment and application of 3-(3,5-dichlorophenyl)-2,4-imidazolidinedione, wherein the preparation method comprises the following steps: S1, continuously inputting dry inorganic acidic gas into a reactor; S2, mixing raw material N-[[(3,5-dichlorophenyl)amino] carbonyl] amino acetic acid and an auxiliary agent and then inputting the mixture into the reactor; S3, under the catalysis of the acidic gas, the raw material and the auxiliary agent perform cyclization reaction to obtain a mixture of 3-(3,5-dichlorophenyl)-2,4-imidazolidinedione, water and the auxiliary agent; and S4, cooling and separating the mixture obtained in the step S3 to obtain 3-(3,5-dichlorophenyl)-2,4-imidazolidinedione solid and an aqueous auxiliary agent solution respectively. The preparation method of 3-(3,5-dichlorophenyl)-2,4-imidazolidinedione has the advantages of continuous production, high efficiency, simplicity, near-zero emission and mild reaction conditions, can effectively shorten the reaction time, improve the production efficiency, reduce the safety risk, and the yield of the product can reach more than 93%, and the purity can reach more than 99%.

The present invention relates to a method for manufacturing a polyurethane urea elastic yarn, characterized by using an imidazolidinone-based organic solvent as an organic solvent for polyurethane urea elastic yarn synthesis, and to a polyurethane urea elastic yarn manufactured thereby. According to the present invention, by using the imidazolidinone-based organic solvent, the reaction can be controlled, thereby obtaining a high-molecular-weight polyurethane urea polymer, and the obtained polyurethane urea solution exhibits excellent transparency, has good storage stability due to the absence of cloudiness even after long-term storage, is not subject to environmental regulations, and can secure stability even under high-temperature process conditions due to a high flash point thereof.

A compound of formula (I) is:wherein: X2 represents a —CO—NRk— group, a —NR′k—CO— group, a —O— group, a —CO— group, a —SO2-group, a —CS—NH— group, a —CH2—NH—, agroup, or a heterocyclyl, wherein the heterocyclyl is a 5- or 6-membered ring comprising 1, 2, 3 or 4 heteroatoms selected from O, S and / or N; Y2 represents a hydrogen atom, a halogen atom, a hydroxyl group, a morpholinyl group, optionally substituted by a (C1-C4)alkyl group or a trifluoromethyl group, a bridged morpholinyl group, a (C5-C11)bicycloalkyl group, an adamantyl group, a piperidinyl group, a (C1-C4)alkenyl group, a —PO(ORa)(ORb) group, a 5-membered heteroaromatic ring or a —CR1R2R3 group, or any of its pharmaceutically acceptable salt.

The application discloses an N-substituted 2-(2,5-dioxoimidazolidin-4-yl) acetamide compound and a synthesis method and application thereof, and belongs to the technical field of tumor immunotherapy drug development.The N-substituted 2-(2,5-dioxoimidazolidin-4-yl) acetamide compound disclosed by the application is a small-molecule ITIM motif inhibitor, the action mechanism of which is to combine with the ITIM motif of tyrosine phosphorylation in the tumor cell membrane, thereby blocking the combination of the ITIM of tyrosine phosphorylation and SH2, making SHP2 always in an inhibition state, simultaneously blocking multiple inhibitory receptor pathways including PECAM-1, PD-1, BTLA, KIR, CD3 and SIRP alpha, and finally improving the anti-tumor activity of immune cells.The experimental data show that the N-substituted 2-(2,5-dioxoimidazolidin-4-yl) acetamide compound can effectively enhance the killing of tumor cells by immune cells, inhibit the growth of tumors, and fully support the application of the compound in tumor immunotherapy.

The invention discloses a flame-retardant high-resilience polyurethane foam packaging material and a preparation method thereof, and belongs to the technical field of new materials, the flame-retardant high-resilience polyurethane foam packaging material can be used for packaging precise instruments, precious equipment and the like, and the flame-retardant high-resilience polyurethane foam packaging material is prepared by foaming a flame-retardant black material A and a flame-retardant white material B to obtain a body material and then soaking the body material in halloysite branched polyethyleneimine and polyacrylic acid suspension in sequence; the A is prepared by mixing a flame retardant, imidazolidinyl urea, isobornyl acrylate and hydroxyethyl acrylate, wherein the flame retardant is prepared by mixing isophorone diisocyanate, benzoguanamine, phosphonitrilic chloride trimer and triethylamine; the component B is prepared by mixing polyester polyol, two polyether polyols, silicone oil, glycerol, water, pentamethyldiethylenetriamine, stannous octoate and a flame retardant F; the F is formed by mixing a ZIF solution G and a flame-retardant solution H; g is formed by mixing 2-methylimidazole and an ethanol solution of cobalt nitrate hexahydrate; h is prepared by mixing and reacting a diethylenetriamine ethanol solution with a mixed solution of ethanol, diphenyl chlorophosphate and triethylamine. The environment-friendly flame-retardant rubber has good flame retardance and resilience and is environment-friendly.

The disclosure provides Group 6 complexes, which, in some embodiments, are useful for catalyzing olefin metathesis reactions. In some embodiments, the compounds are compounds of the following formula: wherein: M is a Group 6 metal atom; X is an oxygen atom, =N-R5, =N-N(R5)(R5') or =N-0-R5, R5 and R5' independently being various substituents, such as aryl or heteroaryl, each optionally substituted; n is 0 or 1; Rz is a neutral ligand; R1 is hydrogen or an organic substituent; R2 is an aryl or heteroaryl group, each optionally substituted; R3 is an anionic ligand; and R4 is an anionic ligand, such as a pyrrolide, a pyrazolide, an imidazolide, an indolide, an azaindolide, or an indazolide, each optionally substituted.

The novel compounds of structural formula (I) and their pharmaceutically acceptable salts are Na v 1.8 channel activity and can be used in the treatment, prevention, management, amelioration, control and inhibition of diseases mediated by Na v 1.8 channel activity. The compounds of the present invention can be used in the treatment, prevention or management of pain conditions, cough conditions, acute itch conditions and chronic itch conditions.

The aluminum foil comprises an aluminum foil base layer and the anti-corrosion coating arranged on at least one surface of the aluminum foil base layer, and paint of the anti-corrosion coating comprises water-based acrylic resin emulsion, water-based antibacterial polyurethane, a curing agent, a catalyst, a flatting agent and first deionized water; the water-based acrylic resin emulsion is obtained from a soft monomer, a hard monomer, a cross-linking monomer and a functional monomer under the action of an emulsifier and an initiator, and the functional monomer comprises hexafluorobutyl acrylate and vinyltriethoxysilane; the waterborne antibacterial polyurethane is obtained by reacting a polyurethane prepolymer with an antibacterial chain extender, a cross-linking chain extender and a hydrophilic chain extender, the antibacterial chain extender is dihydroxy quaternary ammonium salt, and the cross-linking chain extender is imidazolidinyl urea. The anti-corrosion coating for the aluminum foil is modified through the water-based acrylic resin emulsion, antibacterial and multi-crosslinking-point water-based antibacterial polyurethane is compounded, and the antibacterial continuity and corrosion resistance of the coating are improved.