The application provides a preparation method of high-purity double-diglycerol polyacyl
adipate-2 and relates to the technical field of
organic synthesis. The specific steps comprise the following steps: S1, putting double-diglycerol and mixed acid into a reaction kettle, vacuum heating and material mixing, water removal and mixing to obtain material; S2, adding a catalyst to the material to perform
esterification reaction, and measuring the
acid value after the reaction is completed; S3, after the
acid value reaches the standard, cooling under a
vacuum state, and filtering to obtain double-diglycerol polyacyl
adipate-2. All raw materials except the catalyst are preheated and mixed under a
vacuum state in the application, the mixing uniformity of the raw materials is improved, the raw materials are pretreated by water removal under a
vacuum state, the
water content of the material is ensured to be low, the reaction is promoted to proceed in a
positive direction, the catalyst is added after the pretreatment by water removal to perform heat preservation reaction, the reaction is prevented from starting during the material mixing, the first step of the reaction is better controlled, the selectivity of the product is better, the
side reaction is less, the purity of the final product is high, and the process flow is more controllable.