738 results about "Pipette" patented technology

The invention relates to the technical field of biological sample detection equipment, and discloses a biological sample detection card box and a biological sample detection method. The biological sample detection card box comprises a box body assembly, a pipetting suction head and a plunger assembly, wherein the pipetting suction head and the plunger assembly are arranged on the box body assembly; the box body assembly comprises a bottom box, a packaging film, a detection box and an upper box rotationally matched with the bottom box, a sample storage area, a liquid storage area and a detection area are arranged at the end, close to the upper box, of the bottom box, a plurality of detection holes corresponding to the detection area are formed in the end, away from the upper box, of the bottom box, the packaging film seals the liquid storage area, and the detection box is arranged on the bottom box and corresponds to the detection area; the detection box is used for arranging at least two detection tubes for storing detection reagents, and the upper box is provided with a sample adding hole; the pipetting suction head is used for sucking and transferring liquid; the plunger assembly is used for sealing the detection pipe. The biological sample detection card box solves the problem of single detection index in the prior art, so that the practicability is high, and meanwhile, the detection efficiency and precision are improved.

A high-throughput automated chemical synthesis workstation, relating to the technical field of chemical synthesis. The workstation comprises a base. The base is detachably provided with a negative pressure suction filter, a magnetic stirring reactor, a high-throughput chemical reaction module, a pipette tip box, a cover plate, and a liquid storage tank, wherein the negative pressure suction filter and the magnetic stirring reactor can be replaced with other testing instruments; a screw is lap-jointed on the cover plate; a moving device is also mounted on the base, and a tightening assembly, a gripper assembly, and a pipetting assembly are mounted on the moving device; and pipetting is performed by the pipetting assembly, the gripper assembly drives the cover plate to move to the high-throughput chemical reaction module for sealing, and after tightening is performed by the tightening assembly, the gripper assembly drives the sealed module to move to the reactor, thereby achieving real-time observation during remote operation.

The invention relates to the technical field of life science, in particular to a full-automatic nucleic acid extraction system and process, and the system comprises a complete machine frame, a sample adding and waste liquid treatment mechanism, an oscillation magnetic suction heating mechanism, a control system and a screen interaction system. The sample adding and waste liquid treatment mechanism realizes three-dimensional accurate positioning through transverse and longitudinal movement guide rails and a vertical movement assembly, comprises a large piston device and a small piston device which are connected in parallel, and can flexibly switch different volumes of pipettes and share a connector; the oscillation magnetic suction heating mechanism integrates oscillation, heating and magnetic suction functions and is matched with multi-specification suction heads and kits to complete sample treatment. According to the extraction process, all the mechanisms are linked through a control system, and full-flow operation such as sample cracking, solid-liquid separation, magnetic bead purification and elution is automatically completed. The nucleic acid extraction device realizes automation and precision of nucleic acid extraction, improves the operation efficiency and the extraction effect, and is suitable for nucleic acid extraction of samples such as plant tissues, animal tissues, blood and plasmids.

Device for containing liquid, of the type container or circulation circuit, and methods of manufacturing this device. The invention relates to a device (1) for containing liquid, of the type container or thermal regulation circuit with heat transfer fluid, comprising at least one metal wall (2) which has openings (3, 3') for the passage of the liquid through said wall (2), a supply or discharge pipette (4, 4') being present on the external face of said wall (2), at the level of each opening (3, 3') and being connected in a hermetic manner to the opening (3, 3') concerned.Device (1) characterized in that each pipette (4, 4') is a pipette made of thermoplastic material, attached exclusively indirectly to the metal wall (2), around the relevant opening (3, 3'), through an intermediate metal piece (5), assembled directly with the outer face of said metal wall (2), and / or, through an intermediate piece or layer made of thermoplastic material (5'), attached by welding or overmolding onto the outer face (2') of said metal wall (2) or onto an intermediate metal piece (5) assembled directly with said outer face (2') of the metal wall (2). Figure to be published with the abbreviation: Fig. 5A.

The invention belongs to the technical field of laser volume calibration, and particularly relates to a laser volume calibration system for a laboratory portable pipettor, which comprises a volume calibration equipment main body and a calibration container, and is characterized in that the volume calibration equipment main body is integrated with an integrated optical measurement module, a data acquisition and intelligent processing unit and a man-machine interaction module; the height change of the liquid level center point can be accurately measured, the specific forms such as the contact angle, the curvature radius and the depth of the liquid level meniscus can be captured and analyzed in real time through images, the liquid level form correction module can accurately calculate the missing volume caused by the concave meniscus by using the parameters, and the accuracy of the missing volume is improved. According to the method, the actual liquid level height is calculated and compensated to the final actual liquid level height, the systematic measurement deviation caused by neglecting the geometrical shape of the meniscus in a traditional single laser ranging method can be fundamentally solved, the volume measurement precision is remarkably improved, and the calibration precision can be improved to a new level.

A pipette tip extension having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and encloses an inner cavity which is delimited by the inner side of the exterior wall. The exterior wall forms at the proximal end a reception aperture. The pipette tip extension further has one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.

The sealing device comprises a first sealing assembly and a second sealing assembly, the first sealing assembly is arranged at the end, away from a gun head, of an inner cavity, the first sealing assembly comprises a sealing lantern ring, a first pressing plate and a first sealing ring, the sealing lantern ring is embedded in the inner cavity, and the first pressing plate is arranged on the first sealing ring. The first pressing plate is partially embedded in the inner cavity and abuts against the sealing lantern ring, the sealing lantern ring is in interference fit with the outer diameter of the piston rod, and the first sealing ring is arranged on the outer wall of the sealing lantern ring in a sleeving mode so as to apply radial pressing force to the sealing lantern ring; the second sealing assembly is arranged at the joint of the cylinder body and the gun head and comprises a second sealing ring, a second pressing plate and a push plate, the gun head is sleeved with the second sealing ring, the second pressing plate is embedded in the cylinder body and presses the gun head, and the push plate is connected to the cylinder body so as to press the second pressing plate. According to the technical scheme, the sealing effect and durability of the pipettor are improved.

A pipette tip extension attachable to a pipette tip is disclosed. The pipette tip extension has a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip. The pipette tip extension also has a bottom at the distal end, an inner cavity enclosed by the inner side of the exterior wall and the bottom, and one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.

The invention relates to the technical field of medical inspection equipment and portable cold chain control, in particular to a foldable temporary inspection reagent refrigeration box temperature control and pipettor waste liquid early warning system. The system is composed of a semiconductor refrigeration and phase change cold storage composite temperature control unit, a reagent position RFID and expiration management module, a temperature, humidity and vibration monitoring module, a waste liquid collection and liquid level and component monitoring unit, an edge control and information interaction terminal, a pipettor interface control module, a folding state detection module and a power supply and battery management module. 2-8 DEG C closed-loop temperature control and timing temperature return are realized; when the event is close to a threshold value, alarming and prohibiting cover opening, and locking suction and discharge; and recording the cold chain and tracing. According to the technical scheme, 2-8 DEG C closed-loop temperature control and timing temperature returning are achieved, automatic temperature control tightening, cover opening forbidding, suction and exhaust locking and chain type tracing are achieved in the abnormal state, and the problems that temperature control beside a mobile station is disjointed with authority, and tracing is insufficient are solved.

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrates biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins / toxins, viruses, DNA, and / or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect and identify. A single-use pipette tip includes fluid ports for aspirating the sample and connecting to a concentrating unit.

The present application relates to a light-initiated chemiluminescence detection apparatus and detection method. The detection apparatus comprises: a sample feeding module; a reagent module; a pipetting mechanism comprising a first driving assembly and a pipettor, wherein the pipettor can be driven by the first driving assembly to move in a three-dimensional space and can be connected to disposable pipette tips, so as to transfer a sample and a first reagent; a cup grasping mechanism comprising a second driving assembly and a cup grasping assembly, wherein the cup grasping assembly can be used for grasping reaction cups, and is driven by the second driving assembly to perform positional dispatching on the grasped reaction cups; an incubation mechanism, which comprises a rotary disk configured to circumferentially load a plurality of reaction cups, and incubates sample-reagent mixtures in the reaction cups; a detection mechanism, which is arranged on the incubation mechanism and is configured to perform light initiation and detection on the incubated sample-reagent mixtures; and a liquid-filling assembly, which completes at a specific position the filling of a second reagent into the reaction cups. The solution provided in the present application can omit a washing procedure in chemiluminescence analysis and detection, thereby improving the detection efficiency.

The invention provides a liquid level detection method based on air pressure detection, which is applied to a pipetting system, and the pipetting system comprises a suction head; the liquid level detection method comprises the steps that the whole pipetting system is driven to move towards a target container in the first direction, the suction head is driven to suck air in the second direction at the preset speed, and the preset speed is smaller than or equal to 0.6-3 uL / s; detecting real-time air pressure; whether a suction head makes contact with liquid in the target container or not is judged according to the real-time air pressure, and when the suction head makes contact with the liquid, the liquid level position of the liquid is recorded, and the suction head is controlled to stop sucking air. The liquid level detection method based on air pressure detection is beneficial to shortening the pipetting time and improving the pipetting accuracy. The invention further provides a pipetting method and system based on air pressure detection and a computer readable storage medium.

The utility model belongs to the field of medical instruments, and particularly relates to a pressing type quantitative dropper, in the pressing type quantitative dropper, a main pipe body, a soft rubber connecting piece and a pressing piece are integrally formed through injection molding (such as double-color mold injection molding), the pressing piece and the main pipe body are connected through the soft rubber connecting piece, and elastic force for resetting after pressing is provided for the pressing piece every time; according to the design, the pressing piece and the main pipe body are connected without assembling, welding and the like, the structure is simple, the production and manufacturing process is simplified, and machining and manufacturing are convenient.

The present disclosure generally relates to microfluidics, and to systems and methods for controlling the introduction of fluids. For example, certain aspects are generally directed to microfluidic devices having ports able to direct the end of a pipette tip into an end portion that is sized so as to allow fluid to flow from the pipette tip into an exit fluidly connected to a microfluidic channel. For example, the port may have a tapered portion that directs the pipette tip to the end portion. The end portion may be sized such that it is difficult for fluid to backflush around the pipette tip, and thus, the fluid is able to flow into microfluidic channels within the device, e.g., without resulting in excessive fluid remaining within the end portion. Other aspects are generally directed to methods of making or using such microfluidic devices, kits including such microfluidic devices, and the like.

An automated analyzer that receives samples prepared for analysis in an automated pre-analytical module and a method of operation of such automated analyzer. The automated analyzer includes a shuttle transfer station that receives a shuttle carrier from the automated pre-analytical system. The shuttle transfer station has a clamping assembly for the shuttle. The clamping assembly has jaws that advance engagement members into contact with a bottom portion of sample containers disposed in the shuttle. The clamping assembly secures the sample containers in the shuttle when sample is aspirated from the sample containers. The automated analyzer also has a multichannel puncture tool that is adapted to be carried by a robotic gripper mechanism. The multichannel puncture tool has multiple puncture members that each defines a channel. Each channel is in communication with a different trough in the consumable. A pipette can pass through the channel in the puncture tool.

The present invention relates to a mini-pipette, and more particularly, to a mini-pipette which has capacity varying means that can vary the movement distance of a push button reciprocating in the outer body to generate suction force so that a variety of samples can be easily collected. The present invention provides a mini-pipette comprising: an outer body having a hollow movement space and a suction passage formed at a lower part of the outer body; a push button for generating negative or positive pressure in the suction passage while reciprocating in the movement space of the outer body; elastic means for elastically supporting the push button in the movement space; and a capacity varying means formed inside the outer body, for varying a movement distance of the push button in the movement space.

The utility model mainly relates to general chemical or physical experiment equipment, in particular to a multi-channel pipette tip, which comprises a mounting shell with the top communicated with a pipette, linearly arranged mounting holes are arranged at the bottom of the mounting shell, pipette tip bodies are inserted into the mounting holes, first fixing rings are arranged on the pipette tip bodies, and the pipette tip bodies are provided with second fixing rings. Every two adjacent first fixing rings are fixedly connected through a first connecting piece. Mounting rings are arranged on the pipette tip bodies located at the two ends, the side walls of the mounting rings are fixedly connected with one ends of L-shaped rods, the other ends of the L-shaped rods are matched with inserting grooves formed in the bottoms of the mounting shells, sliding grooves are formed in one sides of the inserting grooves in a communicating mode, movable rods are slidably mounted in the sliding grooves, and clamping blocks are fixedly mounted at one ends of the movable rods; and the other end of the movable rod extends to the outer side of the mounting shell and is provided with a handle, a spring is arranged on the movable rod, and the two ends of the spring are connected with the mounting shell and the handle correspondingly.

The invention relates to a pipette comprising a rod-shaped housing, at least one seat for releasable holding of a pipette tip on a lower end of the housing, an expelling device comprising an expelling chamber with an expelling element, a connection channel connecting the expelling chamber with an opening in the seat, a travel lever movable in longitudinal direction in the housing, an operating button connected with an upper end of the travel lever and protruding from the housing, a stop element on an outer circumference of the travel lever, an upper stop for the stop element and a lower stop for the stop element, an adjustment device for adjusting the position of the upper stop in the housing, a display device for displaying an adjusted delivery volume, wherein between the adjustment device and the display device there is a form-locking coupling device which is configured to couple the adjustment device with the display device in an engaged state and to decouple the adjustment device from the display device in a disengaged state.

The utility model discloses a kind of consumable press-fitting devices. Consumable press-fitting device is used to press-fit consumable, and consumable press-fitting device includes adapter base and adapter gland, adapter base is used to support and position consumable, adapter gland is detachably connected with adapter base, and accommodating cavity that can form containing consumable between adapter base and adapter gland, adapter gland includes avoiding hole part. After adapter gland and adapter are disassembled, consumable provided with sealing membrane can be smoothly placed on adapter base, and after adapter gland and adapter base are assembled, avoiding hole part makes part of consumable exposed, and pipette tip can conveniently pass through sealing membrane and enter inside consumable, and adapter gland compresses consumable, so that pipette tip consumable is not taken away, the stability of consumable is good, the continuity of experiment can be guaranteed, and the efficiency of automated pipetting is improved.

The invention relates to the technical field of biochemical detection, and discloses a multitube method coliform group detection device, which solves the problems of long detection period, complicated operation and limited sensitivity of the existing multitube method, and comprises two X-axis linear modules, the number of the X-axis linear modules is two, the two X-axis linear modules are parallel to each other, and the X-axis linear modules are parallel to each other. A first motor and an X-axis sliding table are arranged on the X-axis linear module, a Y-axis linear module is installed on the X-axis sliding table, two Z-axis linear modules are arranged on the Y-axis linear module, a pipettor and a rotary clamping jaw are installed on the two Z-axis linear modules respectively, photoelectric limiting switches and second motors are arranged on the Z-axis linear modules, and a platform is arranged below the X-axis linear module. A pipette head frame and a detection module are fixedly mounted at the top of the platform; compared with a traditional method, the method has the advantages that manual intervention is reduced, the detection efficiency and accuracy are improved, and the method is suitable for rapid microorganism detection in the fields of water quality, food and the like.

This utility model relates to the field of pipette technology, specifically to a rotary pipette holder, comprising a base, a column, and a locking mechanism. The base has a detachable collection box with an upper opening, and the collection box has a through hole in the middle. The column includes a first column and a second column. The lower end of the first column passes through the through hole and is rotatably connected to the base. The upper ends of the first column and the lower ends of the second column are fixed or separated by the locking mechanism. The upper end of the second column has a support member for holding the pipette. The collection structure of this utility model allows for a clear view of the amount of liquid dripped from the pipette, and the collection structure can be detached from the holder for easy cleaning.

The present invention relates to the handling of sampling devices such as a sampling cloth after sampling, by providing a pushing device (100) for securing a sampling device inside a test tube so that a pipette can be used without hindrance by an automated laboratory robot. The pushing device comprises a hollow, elongated body (1) comprising at least two slots (30) configured to allow fluid communication between the exterior space (80) and interior space (70) of the body, and at least two flaps (5) extending outwardly from the body (1) configured to be elastically such that, upon insertion of the pushing device (100) into a test tube (200) the flaps (5) are constrained by the inner wall of the test tube, causing them to retract inwardly and to exert a force against the inner wall of the test tube, thereby securing the pushing device (100) in a fixed position within the test tube (200). The invention further relates to a sampling kit provided with the pushing device (100) and to methods for securing and processing a sampling device using the pushing device (100).

This application relates to a sample pretreatment system, comprising: a gripping device for holding the cap of a sampling tube; a capping device for holding the tube body of the sampling tube and for rotating the tube body while the gripping device holds the cap to open or close the cap; a liquid injection device for injecting organic solvent into the tube body held in the capping device and containing the sample to be tested, to obtain a mixture; a mixing device for mixing the mixture in the sampling tube; a centrifugation device for centrifuging the mixed mixture in the sampling tube to obtain a supernatant; a filtration device for filtering the supernatant to obtain a filtrate; a pipette device for drawing at least a portion of the supernatant from the sampling tube into a pipette or injecting the supernatant from the pipette into the filtration device; and a transport device. This application improves processing efficiency and ensures the consistency of pretreatment results.

1. Name of the designed product: pipette. 2. Use of the designed product: pipetting. 3. Design points of the designed product: in shape. 4. Picture or photo that best shows the design points: perspective view.

According to an example aspect of the present invention, there is provided an adapter for holding a pipette, the adapter comprising a body element, said body element configured to hold a pipette; wherein the adapter is configured to be attached to at least one rail at any point along the rail, said at least one rail comprising at least one electrical conductor, said electrical conductor extending at least partially along the length of the at least one rail.

The invention relates to a single-channel pipette liquid level detection method and device based on an embedded platform, and the method comprises the steps: controlling a Z axis to enable a pipette to descend from a zero point, obtaining a first air pressure difference waveform of the pipette, and adjusting the speed parameter of the Z axis until the first air pressure difference waveform is in a stable state in the descending process; the Z axis is controlled to descend according to the speed parameters, so that the pipette extends into the liquid level, and a second air pressure difference waveform in the pipette is obtained; extracting liquid touching air pressure characteristics in the second air pressure difference waveform, and adding the extracted liquid touching air pressure characteristics into a reagent database; the Z axis is controlled to descend according to the speed parameter, a third air pressure difference waveform in the pipette is obtained, and when the characteristic of the third air pressure difference waveform is matched with the liquid touching air pressure characteristic, it is judged that liquid touching is conducted. The air pressure difference waveform characteristics replace the traditional air pressure threshold to judge whether the liquid is touched or not, so that the stability and adaptability of liquid level detection are improved, and a series of problems caused by detection failure in an extreme environment are effectively avoided.

A method for preparing an aliquot of solution is disclosed. The method includes agitating the solution with a baffle at a predetermined mixing speed to suspend the plurality of particles in the solution, wherein the baffle positioned at least partially within a vessel containing the solution, and wherein the vessel is engaged with a vessel receptacle configured to hold the vessel. The method also includes withdrawing, during the agitating, the aliquot of solution from the vessel with a pipette, such that an end of a pipette tip is positioned within the vessel.

The invention relates to the field of immune cell chemistry, and discloses an immune cell chemical staining instrument and a use method thereof.The immune cell chemical staining instrument comprises a workbench, a sample bearing unit, a temperature control unit, a liquid treatment unit and a dynamic uniform mixing unit, and cover glass in holes of a cell culture plate of the sample bearing unit can bear samples; a reagent in the reagent bin can be added into a hole of the cell culture plate by a pipetting arm of the liquid treatment unit, the temperature control unit can control the temperature of the reagent in the hole of the cell culture plate, and the dynamic uniform mixing unit can drive the cell culture plate to reciprocate, so that liquid in the hole of the cell culture plate is uniformly mixed. Reagents are automatically added through the liquid treatment unit, the experiment operation efficiency is improved, pollution caused by manual intervention is avoided, the reagent temperature is controlled through the temperature control unit, and the experiment accuracy is improved; meanwhile, the dynamic uniform mixing unit is used for driving the cell culture plate to reciprocate, so that the reagent incubation uniform mixing effect is enhanced.

Conveyor system device (82a-e) for the orderly conveying of elongated and / or cylindrically extended objects (10a-e) such as ampoules, cartridges, syringes, pipettes, vials or the like, with at least one object recording unit (14a-e) which is movably mounted along a direction of movement (12a-e) and is designed for the piece-by-piece recording of the individual objects (10a-e), which comprises at least one object gripper (20a-e) forming at least one object holding contact surface (16a-e) and providing for holding a single object (10a-e) in a receiving area (18a-e) of the object receiving unit (14a-e), with at least one first gripper element (22a-e) and with at least one second gripper element (24a-e), characterized by the fact that the first gripper element (22a-e) forms an object-carrying contact surface (26a-e) which is intended to contact the object (10a-e) to be conveyed in at least one operating state and to carry it along with the object-receiving unit (14a-e) and that the second gripper element (24a-e) has an object-guiding contact surface (36a-e) which is intended to guide the movement of the object (10a-e) relative to the first gripper element (22a-e) from a first position (28a-e), in which the object (10a-e) predominantly contacts the object-carrying contact surface (26a-e), to a second position (30a-e), in which the object (10a-e) predominantly contacts the object-holding contact surface (16a-e).

The application provides a pipetting control method and device, the method comprising: determining a pipetting type, a pipetting speed of a pipetting device, a target pipetting volume, an initial liquid volume of a target liquid container, and a container type of the target liquid container; determining a target liquid level height function matched with the container type of the target liquid container according to a liquid level height function corresponding to each container type in a configuration; determining a liquid level height difference of the target liquid container before and after pipetting based on the pipetting type, the target pipetting volume, and the initial liquid volume, and in combination with the target liquid level height function; determining a moving direction and a moving speed of a pipetting tip of the pipetting device based on the liquid level height difference, the target pipetting volume, the pipetting speed, and the pipetting type; and controlling the pipetting tip of the pipetting device to pipette the target liquid container according to the moving direction and the moving speed. The application can reduce the liquid volume deviation of the pipetting device in the pipetting process.