1538 results about "Pipette" patented technology

A structure plumbing flow simulation apparatus is described herein. An example structure plumbing flow simulation apparatus may include: (1) a reservoir configured to hold a set volume of a liquid; (2) a pump connected to the reservoir configured to pump the liquid; (3) a pressure source connected to the pump and configured to pressurize the liquid from the pump which flows to a water shut off valve downstream of the pressure source; (4) one or more pipes connected to the pressure source and adapted to be connected to the water shut off valve; and / or (5) a pipette connected to the one or more pipes.

The utility model provides a pipetting workstation and relates to the technical field of medical instruments. Comprising a base, a pipetting device, a carrier assembly and a waste box, the pipetting device comprises a rack, a pipetting mechanism and an adjusting mechanism, the rack is arranged on the upper end face of the base, the pipetting mechanism is installed on a supporting bottom plate of the rack, and the pipetting mechanism comprises an X-direction moving assembly, a Y-direction moving assembly and a Z-direction moving assembly; the first end of the Y-direction moving assembly is fixedly connected to the X-direction moving assembly, the Z-direction moving assembly is movably connected to the Y-direction moving assembly in the Y direction, and the pipette is movably connected to the Z-direction moving assembly in the Z direction; the adjusting mechanism is connected with the second end of the Y-direction moving assembly so as to adjust the Y-direction moving assembly to be in a horizontal state; the carrier assembly and the waste box are arranged on the supporting bottom plate, the carrier assembly is used for containing a container, and the waste box is used for containing waste. According to the pipetting workstation, the pipetting precision and the pipetting stability can be improved, and pipetting and waste liquid treatment can be systematically completed.

To precisely locate a position of a pipette tip to a designated position of a reservoir and to a designated well of a well plate.SOLUTION: A dispensing device includes: a dispensing head in which a liquid suction and discharge device is arranged; a plurality of pipette tips which are attached to the dispensing head; a moving mechanism which moves the dispensing head; a from-below imaging device for imaging the plurality of pipette tips from below; a from-top imaging device for imaging the reservoir and well plate from above; a lower-side image recognition unit which recognizes a horizontal position of the pipette tip relative to the dispensing head; an upper-side image recognition unit which recognizes a horizontal position of the reservoir and a horizontal position of the well plate; a path determination unit which determines a movement path of the dispensing head for each pipette tip to be used depending on the horizontal positions of the pipette tip, the reservoir, and the well plate; and a drive control unit which controls the movement mechanism according to the movement path determined by the path determination unit.SELECTED DRAWING: Figure 1

A vacuum adsorption device with an adsorption area capable of being freely and automatically adjusted in size and shape is characterized in that one end of a strip-shaped magnetic-inlaid sealing gasket is connected with a rolling assembly, the other end of the strip-shaped magnetic-inlaid sealing gasket is adsorbed above a sealing gasket adsorption platform, and the strip-shaped magnetic-inlaid sealing gasket located above the sealing gasket adsorption platform is closed to form an adsorption cavity; the outer shaping magnet is located outside the adsorption cavity, the inner shaping magnet is located inside the adsorption cavity, and the outer shaping magnet and the inner shaping magnet are both adsorbed on the sealing gasket adsorption platform; the position adjustment driving assembly drives the rotating T-axis module and the rotating strong magnetic head to move horizontally, the rotating T-axis module drives the rotating strong magnetic head to rotate, and the rotating strong magnetic head drives the outer shaping magnet and the inner shaping magnet to adjust the size and shape of an adsorption cavity formed by the strip-shaped magnetic-inlaid sealing gasket; the vacuum supply system comprises a vacuum port air pipe, and the end of the vacuum port air pipe communicates with the interior of the adsorption cavity. The size and the shape of the adsorption area can be adjusted at will.

The utility model provides a pipetting device and relates to the technical field of medical instruments. The pipetting device comprises a rack, a pipetting mechanism and an adjusting mechanism, the pipetting mechanism is installed on a bottom plate of the rack and comprises an X-direction moving assembly, a Y-direction moving assembly and a Z-direction moving assembly, the X-direction moving assembly is movably connected to the bottom plate in the X direction, the first end of the Y-direction moving assembly is fixedly connected to the X-direction moving assembly, and the second end of the Y-direction moving assembly is fixedly connected to the Z-direction moving assembly. The Z-direction moving assembly is movably connected to the Y-direction moving assembly in the Y direction, the Z-direction moving assembly is provided with a fixing frame movably connected in the Z direction, and the fixing frame is used for installing a pipettor; the adjusting mechanism is connected with the pipetting mechanism so as to adjust the pipetting mechanism to be in a horizontal state. The pipetting device can improve the pipetting precision and the pipetting stability.

A microplate holder comprises a top shell portion comprising a plurality of holes constructed and arranged to receive a pipette; and a bottom shell portion constructed and arranged to couple to the top shell portion, the top shell portion and the bottom shell portion configured to at least partially enclose a microplate having a plurality of wells vertically aligned with the plurality of holes of the top shell portion, the bottom shell portion having a bottom region that exposes a bottom surface of the microplate to a light generating source that provides backside illumination for a photoactivation process regarding liquid contents of the microplate.

The invention relates to the technical field of biological sample detection equipment, and discloses a biological sample detection card box and a biological sample detection method. The biological sample detection card box comprises a box body assembly, a pipetting suction head and a plunger assembly, wherein the pipetting suction head and the plunger assembly are arranged on the box body assembly; the box body assembly comprises a bottom box, a packaging film, a detection box and an upper box rotationally matched with the bottom box, a sample storage area, a liquid storage area and a detection area are arranged at the end, close to the upper box, of the bottom box, a plurality of detection holes corresponding to the detection area are formed in the end, away from the upper box, of the bottom box, the packaging film seals the liquid storage area, and the detection box is arranged on the bottom box and corresponds to the detection area; the detection box is used for arranging at least two detection tubes for storing detection reagents, and the upper box is provided with a sample adding hole; the pipetting suction head is used for sucking and transferring liquid; the plunger assembly is used for sealing the detection pipe. The biological sample detection card box solves the problem of single detection index in the prior art, so that the practicability is high, and meanwhile, the detection efficiency and precision are improved.

The present invention discloses a pipette tip comprising a molded body made from an electrically insulating material, with an outer surface, an inner surface, and a translucent or transparent feature allowing visibility through both surfaces. The pipette tip further includes at least one impedance or capacitance electrode made from an electrically conductive material, positioned on the outer surface away from the translucent or transparent feature. Each electrode is electrically isolated on the outer surface, ensuring accurate and reliable measurements during liquid handling operations. This innovative design provides enhanced visibility and precise electrical measurements, making the pipette tip ideal for various laboratory applications.

The invention discloses air tightness detection equipment, and aims to provide high-efficiency transfer pipette air tightness detection equipment with high automation degree and good detection effect and a control method of the transfer pipette air tightness detection equipment. According to the technical scheme, transfer pipettes are conveyed through a transmission belt and a material placing mechanism on the transmission belt; the transmission belt drives the pipette to complete the detection of the air tightness of the pipette through the air tightness detection device, and meanwhile, the air tightness detection mode is that one end of the pipette to be detected is blocked and the other end of the pipette is subjected to air exhaust, so that the air pressure in the pipette is reduced, and a pressure maintaining link is added after the air exhaust is completed; the air pressure of the transfer pipette is detected in the pressure maintaining process, so that the air tightness of the transfer pipette is conveniently detected, unqualified products can be automatically removed, the overall automation degree is high, the overall processing efficiency is improved by arranging multiple groups of material blocking assemblies and air exhaust assemblies, and the transfer pipette detection device is suitable for the technical field of transfer pipette detection.

A high-throughput automated chemical synthesis workstation, relating to the technical field of chemical synthesis. The workstation comprises a base. The base is detachably provided with a negative pressure suction filter, a magnetic stirring reactor, a high-throughput chemical reaction module, a pipette tip box, a cover plate, and a liquid storage tank, wherein the negative pressure suction filter and the magnetic stirring reactor can be replaced with other testing instruments; a screw is lap-jointed on the cover plate; a moving device is also mounted on the base, and a tightening assembly, a gripper assembly, and a pipetting assembly are mounted on the moving device; and pipetting is performed by the pipetting assembly, the gripper assembly drives the cover plate to move to the high-throughput chemical reaction module for sealing, and after tightening is performed by the tightening assembly, the gripper assembly drives the sealed module to move to the reactor, thereby achieving real-time observation during remote operation.

The technology relates in part to a segmented pipette tip adapter that includes a plurality of plate segments and a junction between adjacent plate segments. Each of the plate segments often includes a proximal surface, a distal surface, edges, one or more nozzles disposed on the proximal surface, and one or more tubular projections disposed on the distal surface. Each of the nozzles often includes a nozzle bore, each of the tubular projections often includes a tubular projection bore, each of the plate segments often includes a plate bore disposed at each of the nozzles, and each nozzle bore often is aligned with a tubular projection bore and a plate bore. Each junction often is between adjacent edges of a pair of adjacent plate segments.

The utility model discloses a sample treatment and detection integrated device, and belongs to the field of medical examination and inspection instruments and molecular diagnosis and detection instruments. According to the technical key points, the system comprises a system outer cover assembly, a loading round chassis assembly and a rotary liquid transfer device assembly, the object-carrying circular chassis assembly comprises an object-carrying circular chassis; a waste liquid bin, a magnetic bead lysis solution bin, a reagent tube, a PCR tube and a washing liquid bin are uniformly arranged on the loading round chassis; an insertion cylinder is further arranged in the middle of the loading round base plate; the rotary liquid transfer device assembly comprises a rotary liquid transfer device; the offset pipette comprises an upper through pipe interface, a lower pipe interface and an offset pipe; the lower portion of the first vertical through pipe is connected with the upper through pipe connector, and the upper portion of the second vertical pipe is connected with the lower through pipe connector. The first vertical through pipe and the second vertical pipe are located on the same vertical axis, and the first vertical through pipe is communicated with the offset pipe.

The invention relates to a high-precision micro-pipetting device and a control method thereof, and the pipetting device, the high-precision micro-pipetting device comprises a control module, a positive pressure system, a negative pressure system, a three-way solenoid valve and a pipetting head, the control module controls the switching of the three-way solenoid valve to enable a micro-control solenoid valve to be communicated with the positive pressure system or the negative pressure system, and the control module controls the opening time of the micro-control solenoid valve; a proportional valve, a pressure sensor and a flow sensor are arranged between the three-way electromagnetic valve and the micro-control electromagnetic valve, the proportional valve is used for adjusting the pressure and the flow of a gas circuit, and the control module conducts PID control on the proportional valve according to measurement data of the pressure sensor and the flow sensor. The positive / negative pressure value and the gas flow rate of the gas circuit are adjusted through the proportional valve, so that the positive / negative pressure at the liquid suction head can be changed, the suction and discharge of samples with different viscosities can be realized, the switching time of the liquid suction head is controlled through the micro-control electromagnetic valve, and the sample amount of each time of pipetting can be accurately controlled.

The invention relates to the technical field of cell passage, and particularly discloses a cell passage device which comprises a pipetting mechanism, a material standby mechanism and an uncovering mechanism, the pipetting mechanism comprises a space mover and a pipetting assembly installed at the output end of the space mover, and the space mover is used for driving the pipetting assembly to move in the space; the material standby mechanism is used for placing test tubes, opening test tubes filled with liquid raw materials and opening standby test tubes; the cover opening machine is used for opening and closing covers of the culture dishes; the pipetting assembly comprises a pressing device, a rotating base and a plurality of pipetting guns, the rotating base and the pressing device are both installed at the output end of the space mover, the pipetting guns are distributed in the circumferential direction of the rotating base, the rotating base is used for rotating the pipetting guns to work stations, and the pressing device is used for pressing pressing heads of the pipetting guns located at the work stations to suck liquid or discharge the liquid; the pressing device is used for pressing a push head rod after the push head rod is aligned to the pipette to replace the pipette head; the pipetting mechanism further comprises a waste container located below the pipetting gun and a gun head set containing a plurality of gun heads of different specifications, the pipetting gun can be inserted into the gun heads of the gun head set to assemble new gun heads, and the gun heads or waste liquid pushed out of the pipetting gun can be received by the waste container. According to the scheme, the automatic operation of cell passage is realized, the automatic suction of the pipette and the automatic replacement of the pipette head can be realized in the pipetting process, and the control simplicity and convenience of the pipetting mechanism are ensured.

The invention relates to the technical field of life science, in particular to a full-automatic nucleic acid extraction system and process, and the system comprises a complete machine frame, a sample adding and waste liquid treatment mechanism, an oscillation magnetic suction heating mechanism, a control system and a screen interaction system. The sample adding and waste liquid treatment mechanism realizes three-dimensional accurate positioning through transverse and longitudinal movement guide rails and a vertical movement assembly, comprises a large piston device and a small piston device which are connected in parallel, and can flexibly switch different volumes of pipettes and share a connector; the oscillation magnetic suction heating mechanism integrates oscillation, heating and magnetic suction functions and is matched with multi-specification suction heads and kits to complete sample treatment. According to the extraction process, all the mechanisms are linked through a control system, and full-flow operation such as sample cracking, solid-liquid separation, magnetic bead purification and elution is automatically completed. The nucleic acid extraction device realizes automation and precision of nucleic acid extraction, improves the operation efficiency and the extraction effect, and is suitable for nucleic acid extraction of samples such as plant tissues, animal tissues, blood and plasmids.

Described herein are various fluid provision systems that may be used in a laboratory setting. The fluid provision systems minimize waste of pipetted liquid sample or reagents and may be used, e.g., in combination with a multi-well plate such as in NGS processes. Other systems include those configured for compatibility with centrifuge rotors or multichannel pipettes with 12 or more channels.

Devices, kits, and methods for samples, including devices, kits, and methods for the collection, transport, and / or testing of semen samples are described herein. A kit for a sample is provided, which includes a sample device having a body, a first cap configured to removably couple to the body at a first open end, and a second cap configured to removably couple to the body at a second open end. A cap can include an opening and a removable plug to seal the opening and / or a seal that receives a pipette and automatically seals when the pipette is removed. The kit can include a stand for holding one or more sample devices and / or a preservative suitable for preserving the sample at room temperature for between 1-120 hours or more.

The food safety detection equipment disclosed by the invention comprises a sampling mechanism, a multi-station turntable device, a centrifugal device, a conveying mechanism, a detection device, a reagent adding device and an extraction mechanism. The sampling mechanism is provided with a sampling table; the multi-station turntable device is provided with a first containing part; the centrifugal device comprises a rotating frame and a first driving mechanism, and the rotating frame is provided with a second containing part; the first conveying mechanism is used for transferring the sample containers among the sampling mechanism, the multi-station turntable device and the centrifugal device; the detection device is provided with a third containing part, a fourth containing part, a first image acquisition device and a second image acquisition device; the reagent adding device is used for adding reagents to form a first sample and a second sample; the extraction mechanism comprises a manipulator and a pipette and is used for extracting the first sample and the second sample. The device has the advantages of high automation degree, good soaking and purifying effects, high detection precision and integration of multiple detection means.

The invention relates to the technical field of liquid transfer, and in particular to a pipette, comprising a ring tube and a driving rod arranged inside the ring tube, an operating button fixedly connected to the driving rod and enabling the pipette to aspirate or discharge liquid, an adjusting component capable of driving the driving rod to reciprocate along its own axis to achieve range adjustment, and a counter component for displaying the range of the pipette, wherein the counter component comprises a mechanical counter, a first driven gear is arranged at the input end of the mechanical counter, the adjusting component comprises a linkage member capable of driving the first driven gear to rotate and an adjusting knob, the adjusting knob is sleeved on the operating button and rotatably connected to the adjusting knob, the adjusting knob is arranged inside the ring tube and can reciprocate along the axial direction of the driving rod to achieve connection and disconnection with the linkage member, and a limiting member for fixing the position of the adjusting knob is arranged on the ring tube, thereby achieving the effect of improving the accuracy of the pipette.

The invention discloses a six-degree-of-freedom precise pipettor adjusting platform based on friction driving and pressure feedback, and relates to the field of laboratory equipment.The adjusting platform comprises a platform shell, a top cover fixed to the top of the platform shell and an objective table arranged on the inner side of the platform shell and used for installing a pipettor; a pitching supporting mechanism is installed on the inner side of the platform shell, and a plurality of pitching posture adjusting mechanisms are installed on the top of the top cover. The pitch attitude adjusting mechanism comprises a supporting base fixed to the top of the top cover, a friction box fixed to the top of the supporting base and a friction rod connected to the friction box in a sleeving mode. By adopting the friction driving technology, the problem of mechanical clearance of a traditional gear or a ball screw is effectively solved, and the multi-dimensional parallel platform has the advantages of low cost, low noise and high response speed, so that the multi-dimensional parallel platform can perfectly replace a traditional six-foot parallel platform, and high-precision and quick response adjustment of a pipette tip in a multi-dimensional direction is realized.

Device for containing liquid, of the type container or circulation circuit, and methods of manufacturing this device. The invention relates to a device (1) for containing liquid, of the type container or thermal regulation circuit with heat transfer fluid, comprising at least one metal wall (2) which has openings (3, 3') for the passage of the liquid through said wall (2), a supply or discharge pipette (4, 4') being present on the external face of said wall (2), at the level of each opening (3, 3') and being connected in a hermetic manner to the opening (3, 3') concerned.Device (1) characterized in that each pipette (4, 4') is a pipette made of thermoplastic material, attached exclusively indirectly to the metal wall (2), around the relevant opening (3, 3'), through an intermediate metal piece (5), assembled directly with the outer face of said metal wall (2), and / or, through an intermediate piece or layer made of thermoplastic material (5'), attached by welding or overmolding onto the outer face (2') of said metal wall (2) or onto an intermediate metal piece (5) assembled directly with said outer face (2') of the metal wall (2). Figure to be published with the abbreviation: Fig. 5A.

The present disclosure relates to a dropper container, which includes: a container body for accommodating contents; and a pipette cap for coupling to the container body, wherein at least a portion of the pipette cap is formed integrally with a pipette for dispensing the contents.

The invention belongs to the technical field of laser volume calibration, and particularly relates to a laser volume calibration system for a laboratory portable pipettor, which comprises a volume calibration equipment main body and a calibration container, and is characterized in that the volume calibration equipment main body is integrated with an integrated optical measurement module, a data acquisition and intelligent processing unit and a man-machine interaction module; the height change of the liquid level center point can be accurately measured, the specific forms such as the contact angle, the curvature radius and the depth of the liquid level meniscus can be captured and analyzed in real time through images, the liquid level form correction module can accurately calculate the missing volume caused by the concave meniscus by using the parameters, and the accuracy of the missing volume is improved. According to the method, the actual liquid level height is calculated and compensated to the final actual liquid level height, the systematic measurement deviation caused by neglecting the geometrical shape of the meniscus in a traditional single laser ranging method can be fundamentally solved, the volume measurement precision is remarkably improved, and the calibration precision can be improved to a new level.

A pipette tip extension having a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end is disclosed. The exterior wall has an outer side and an inner side and encloses an inner cavity which is delimited by the inner side of the exterior wall. The exterior wall forms at the proximal end a reception aperture. The pipette tip extension further has one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.

The invention relates to a PRP preparation device and a PRP preparation method, the preparation device comprises a pipe body, an upper cover, a lower cover and a sealing plug, the pipe body comprises an upper section pipe, a middle pipe and a lower section pipe, the upper cover and the upper section pipe are matched to form an upper cavity, the upper cover can move up and down to enable the upper cover to be switched between a first position and a second position, and the upper cover is provided with a liquid injection and suction hole, a liquid suction pipe and a sealing piece; the lower cover is matched with the lower section pipe to form a lower cavity, and the lower cover can move up and down to adjust the volume of the lower cavity; the sealing plug is used for controlling opening and closing of the liquid injection and suction hole and the liquid suction pipe; the part, located in the upper cavity, of the pipette has a set length, and the set length enables the pipette to be located in the platelet-poor plasma layer and keep a gap with the platelet-rich plasma layer when the pipette is located at the second position, and enables the port of the pipette to be located outside the platelet-rich plasma when the port of the pipette is located at the first position. By applying the device, the PRP concentration can be directly adjusted in the preparation device, and the damage to platelets can be avoided when the PRP is extracted.

The present invention relates to the technical field of in vitro diagnosis, and discloses a sample treatment detection device and a sample treatment device.The sample treatment device comprises: a sample treatment module, which is provided with a sample adding channel and a plurality of solution bins, at least one solution bin is internally provided with magnetic beads for adsorbing nucleic acid or protein, the bottom of the solution bin is communicated with a closed pipette, and the pipette is provided with a sealing gasket; the liquid driving device is arranged in the sample processing module, and a syringe needle at the bottom of the liquid driving device can be inserted into the sealing gasket; at least one of the liquid driving device and the solution bin moves relatively under the driving of the power mechanism, so that the syringe needle of the liquid driving module is inserted into the pipette channels corresponding to different solution bins. The sample treatment device is high in pipetting efficiency, capable of improving the detection efficiency, compact in structure, small in size and wide in application range.

The invention discloses a preparation method of a dry chemical reagent for creatine content determination. The preparation method comprises the following steps: S1, preparing a buffer reagent and a protective component; s2, dissolving the biological enzyme and the chromophoric substrate to form a dissolving reagent; s3, coating by using a biological film-forming material to form a coating reagent; s4, coating and printing the coating reagent in the pore channel of the specified bottom plate base material in a volume quantitative manner by virtue of equipment; the equipment comprises a single-channel type pipettor, a multi-channel type pipettor, a continuous multi-gear distributor or automatic dot printing equipment. S5, placing the specified bottom plate base material printed with the coating reagent in forced air drying equipment or drying equipment with the same efficiency; and S6, measuring the moisture content after drying and film forming, and judging whether substances containing biologically active enzymes and substrates in the reagent are completely locked to the position of the net-shaped cavernous body structure of the biological film forming material or not based on the moisture content. The invention further discloses application of the dry chemical reagent for determining the creatine content, and the dry chemical reagent is applied to a sample formed by urine, serum or tissue.

A rectangular shaped pipette tip carrier (1) comprising a rectangular shaped top plate, a peripheral wall (4) surrounding the top plate (3) and connecting the top plate to a rectangular skirt (5) vertically distanced from the top plate, a plurality of vertically oriented hollow cylinders (6) defining a matrix of passages (8) through the pipette tip carrier for detachably holding disposable pipette tips, a plurality of ribs (9) connecting the hollow cylinders to another and a plurality of skirt ribs (10) connecting the top surface of the rectangular skirt (5) to the peripheral wall (4). The carrier further comprises at least one opening (11) in the longitudinal side (12) or the transverse side (13) of the rectangular skirt (5) providing a passage for a protrusion of a packaging or a passage for a protrusion of a spacer configured to be positioned on top of the pipette tip carrier.

The sealing device comprises a first sealing assembly and a second sealing assembly, the first sealing assembly is arranged at the end, away from a gun head, of an inner cavity, the first sealing assembly comprises a sealing lantern ring, a first pressing plate and a first sealing ring, the sealing lantern ring is embedded in the inner cavity, and the first pressing plate is arranged on the first sealing ring. The first pressing plate is partially embedded in the inner cavity and abuts against the sealing lantern ring, the sealing lantern ring is in interference fit with the outer diameter of the piston rod, and the first sealing ring is arranged on the outer wall of the sealing lantern ring in a sleeving mode so as to apply radial pressing force to the sealing lantern ring; the second sealing assembly is arranged at the joint of the cylinder body and the gun head and comprises a second sealing ring, a second pressing plate and a push plate, the gun head is sleeved with the second sealing ring, the second pressing plate is embedded in the cylinder body and presses the gun head, and the push plate is connected to the cylinder body so as to press the second pressing plate. According to the technical scheme, the sealing effect and durability of the pipettor are improved.

A pipette tip extension attachable to a pipette tip is disclosed. The pipette tip extension has a proximal end, a distal end, and an exterior wall extending between the proximal end and the distal end. The exterior wall has an outer side and an inner side and forms at the proximal end a reception aperture for inserting a pipette tip. The pipette tip extension also has a bottom at the distal end, an inner cavity enclosed by the inner side of the exterior wall and the bottom, and one or more distance elements arranged at the inner side of the exterior wall and protruding into the inner cavity.