The invention discloses a medicine pounding tank, and relates to the technical field of pounding appliances. The medicine pounding tank comprises a tank body device, a top cover, a medicine pounding device and a conical ring, wherein the top cover is connected to the top of the tank body device in a matched mode, the conical ring is fixed at the center of the bottom of the top cover and is located on the surface of the medicine pounding device, an inner tank is arranged inside an outer tank, a reset spring is fixed between the two sides, corresponding to the top of the surface of the inner tank, of the top of the outer tank, an elastic air bag is placed at the center of the bottom of the inner wall of the outer tank, an inner cavity is formed inside the outer tank, the air outlet end of the elastic air bag communicates with the inner cavity, and a knocking device is arranged inside the outer tank and is located in the inner cavity. According to the medicine pounding tank, the self-cleaning effect is achieved, the power of the medicine pounding tank during medicine pounding is fully utilized, residual powder on the side wall is automatically cleaned through impact and air flow, meanwhile, the medicine pounding is rapid and thorough, time and labor are saved, and the working efficiency and the use performance are improved.