1271results about "Electroencephalography" patented technology

Described are patient data communication devices that may be used as wearable patient monitors. The devices are adapted to accept essentially any type of data from essentially any data source, and are reconfigurable, such that each device can determine which data inputs and outputs should be active, and can reconfigure itself based on new configuration instructions. The devices include wireless transceiver units that allow them to form networks, and particularly mesh networks, with other devices. In a mesh network, any one of the devices may serve as a data source, a data forwarder, or a data sink, and the processor of each device may determine whether data should be outputted, displayed, or processed on the local device or on a remote device in the network. Data from other devices in a mesh network may be accepted selectively, depending on the number of hops between the sending and receiving devices.

A patient module comprising an 8 channel EEG pre-amplifier whose signal acquisition and processing characteristics are optimized for use in the operating room and intensive care unit. This patient module comprises at least an optimized multistage input filter, an optimized input stage circuit topography, ultra-isolation, oversampling, a multiplexer inter-sample charge dump, and high performance low-frequency-enhanced shielding.

A wireless, programmable system for medical monitoring includes a base unit and a plurality of individual wireless, remotely programmable biosensor transceivers. The base unit manages the transceivers by issuing registration, configuration, data acquisition, and transmission commands using wireless techniques. Physiologic data from the wireless transceivers is demultiplexed and supplied via a standard interface to a conventional monitor for display. Initialization, configuration, registration, and management routines for the wireless transceivers and the base unit are also described.

The invention relates generally to a medical device wireless adapter, and more particularly, to a module that adapts an existing legacy or newly designed medical device to a healthcare provider's wireless infrastructure.

The present invention provides methods, devices, and systems for wireless physiological sensor patches and systems which incorporate these patches. The systems and methods utilize a structure where the processing is distributed asymmetrically on the two or more types of ASIC chips that are designed to work together. The invention also relates to systems comprising two or more ASIC chips designed for use in physiological sensing wherein the ASIC chips are designed to work together to achieve high wireless link reliability/security, low power dissipation, compactness, low cost and support a variety of sensors for sensing various physiological parameters.

The present invention involves method and apparatus for analyzing two measured signals that are modeled as containing primary and secondary portions. Coefficients relate the two signals according to a model defined in accordance with the present invention. In one embodiment, the present invention involves utilizing a transformation which evaluates a plurality of possible signal coefficients find appropriate coefficients. Alternatively, the present invention involves using statistical functions or Fourier transform and windowing techniques to determine the coefficients relating to two measured signals. Use of this invention is described in particular detail with respect to blood oximetry measurements.

A single-use, self-contained device to monitor at least one physiological parameter of a subject includes a physiological sensor to sense a subject physiological parameter and generate a physiological signal. An integrated circuit is coupled to the at least one physiological sensor and processes the physiological signal. An indicator is electrically coupled to the integrated circuit and indicates information associated with the physiological parameter or the subject. A power source is electrically coupled to the physiological sensor and the indicator. A housing carries the physiological sensor, the integrated circuit, the indicator and the power source. The device includes means for limiting the device to a single use.

A system and method for monitoring and controlling the administration of at least one drug having anesthetic properties are provided. In certain embodiments, the method includes assembling physiological data, obtained from a plurality of sensors placed on a subject, into sets of time-series data, separating, from the sets of time-series data, a plurality of low frequency signals, and determining, from the plurality of low frequency signals, at least one of coherence information and synchrony information. The method can also include identifying, using the at least one of the coherence information and the synchrony information, spatiotemporal signatures indicative of at least one of a current state and a predicted future state of the patient consistent with the administration of at least one drug having anesthetic properties and generating a report indicating at least one of the current state and the predicted future state of the patient induced by the drug.

A portable patient monitor has an integrated mode in which it operates as a plug-in module for a multiparameter patient monitoring system (MPMS). The patient monitor also has a portable mode in which it operates separately from the MPMS as a battery-powered handheld or standalone instrument. The patient monitor has a sensor port that receives a signal indicative of physiological parameters as input to an internal processor. The patient monitor processes this sensor signal to derive patient measurements. In the portable mode, this information is provided on its display. In the integrated mode, the patient monitor provides patient measurements to the MPMS to be displayed on a MPMS monitor.

This invention provides methods and systems for the analysis of data returned from monitoring multiple physiological parameters of a subject, especially from ambulatory multiple parameter monitoring. The methods and systems remove motion artifacts from signals and separate multiple components of single signals due to two or more physiological systems or processes. Each output signal is are preferably free from motion artifacts and reflects primarily functioning of only a single physiological system or process.

A sleep quality assessment approach involves collecting data based on detected physiological or non-physiological patient conditions. At least one of detecting patient conditions and collecting data is performed using an implantable device. Sleep quality may be evaluated using the collected data by an imlantable or patient-external sleep quality processor. One approach to sleep quality evaluation involves computing one or more summary metrics based on occurrences of movement disorders or breathing disorders during sleep.

The present invention provides methods and systems for patient-specific seizure onset detection. In one embodiment, at least one EEG waveform of the patient is recorded, and at least one epoch (sample) of the waveform is extracted. The waveform sample is decomposed into one or more subband signals via a wavelet decomposition of the waveform sample, and one or more feature vectors are computed based on the subband signals. A seizure onset can then be identified based on classification of the feature vectors to a seizure or a non-seizure class by comparing the feature vectors with a decision measure previously computed for that patient. The decision measure can be derived based on reference seizure and non-seizure EEG waveforms of the patient. In another aspect, similar methodology is employed for automatic detection of alpha waves. In other aspects, the invention provides diagnostic and imaging systems that incorporate the above seizure-onset and alpha-wave detection methodology.

A system and method for monitoring and controlling the administration of at least one drug having anesthetic properties are provided. The method includes arranging a plurality of sensors configured to acquire physiological data from a patient and reviewing the physiological data from the plurality of sensors and an indication from a user interface. The method also includes assembling the physiological data into sets of time-series data and analyzing the sets of time-series data to determine signature profiles consistent with the administration of at least one drug. The method further includes identifying, using signature profiles, at least one of a current state and a predicted future state of the patient, controlling the administration of the least one drug to attain the predicted future state, and then generating a report including information regarding at least one of the current state and the predicted future state of the patient induced by the drug.

Devices, systems, and methods are provided for wirelessly powering and/or communicating with microchip devices used for the controlled exposure and release of reservoir contents, such as drugs, reagents, and sensors. In one embodiment, the system includes (1) a microchip device comprising a substrate having a plurality of reservoirs containing reservoir contents for release or exposure; and (2) a rechargeable or on-demand power source comprising a local component which can wirelessly receive power from a remote transmitter wherein the received power can be used, directly or following transduction, to activate said release or exposure of the reservoir contents. In another embodiment, the system comprises (1) a microchip device comprising a substrate a plurality of reservoirs containing reservoir contents for release or exposure; and (2) a telemetry system for the wireless transfer of data between the microchip device and a remote controller.

The present invention comprises a fabric-based sensor for monitoring vital signs or other electrical impulses of a subject. The sensor is woven or knitted from conductive fibers and, when in contact with the body, receives signals from the wearer and transmits them to a processing or monitoring device through a data-output terminal. The sensor may be integrated into the fabric of a garment or used independently as a conductive patch. Additionally, the sensor may provide bi-directional communication by both monitoring electrical impulses and sending them.

An electrode with three-dimensional capabilities for detection and control of brain state changes of a subject. The electrode includes a disk portion having an upper surface and a lower surface, and a shaft portion secured to and extending perpendicularly outwardly from the lower surface of the disk portion; the shaft portion having an outer surface. The disk portion and shaft portion may include one or more recording or stimulating contact surfaces structured to operatively interact with the brain of a subject. Insulating material isolates each of the recording or stimulating contact surfaces from each other. At least one conductor operatively and separately connect each of the recording or stimulating contact surfaces in communication with external apparatus. The disk portion and shaft portion are structured relative to each other to operatively provide support and anchoring for each other while providing three-dimensional capabilities for detection and control of brain state changes of a subject. Modified embodiments include insertible/retractable electrode wires, both contained in channels and sheathed in axially displaceable cannulae; activating mechanisms for inserting/retracting the electrode wires and/or cannulae; and multiple shaft portions.

Preferred embodiments of the invention employ a portable and wearable EEG monitoring device having a patient-worn amplifier releasably coupled to a host computer for transmitting EEG signals. When patient disconnection from the host computer is desired, a portable operations device (POD) can be connected to the amplifier. Preferably upon detecting disconnection, a controller causes new EEG signals to be routed to a removable memory or transmitter peripheral card, enabling seamless data acquisition. Upon detecting reconnection between the amplifier and the host computer, the controller causes new EEG signals to be routed to the host computer. The controller also preferably transmits EEG signals stored on the peripheral memory card (if used) to the host computer. Preferred embodiments include a handheld display apparatus for viewing EEG signals and electrode information. Also, preferred embodiments reduce patient tethers by connecting multiple amplifiers in a daisy-chain format (most preferably on a PAN bus).

A system (10) analyzes signals representative of a subject's brain activity in a signal processor (12) for information indicating the subject's current activity state and for predicting a change in the activity state. One preferred embodiment uses a combination of nonlinear filtering methods to perform real-time analysis of the electro-encephalogram (EEG) or electro-corticogram (ECoG) signals from a subject patient for information indicative of or predictive of a seizure, and to complete the needed analysis at least before clinical seizure onset. The preferred system then performs an output task for prevention or abatement of the seizure, or for recording pertinent data.

A physiological monitoring garment includes first and second elastic fabric portions. An elongate stretchable textile data/power bus is disposed between the first and second elastic fabric portions. The elongate stretchable textile data/power bus includes a plurality of integral conductors, woven, knitted, or braided along the length thereof. One or more sensors are connected to the elongate stretchable textile data/power bus.

A wearable system or garment comprises at least three conductive electrodes that may, for example, be made of stretch-recovery electrically conductive yarns integrated with non-conductive stretch-recovery yarns that make up the remaining portion of the wearable system or garment. The wearable or garment further comprises means for using three electrodes to monitor at least one physiological or biophysical event or characteristic of the wearer. One electrode is specifically used to feed back an inverted noise signal to the wearer to destructively interfere with the wearer generated noise. Specifically, the wearer's heart rate, ECG and associated electrical characteristics may be monitored in high resolution under dry electrode conditions.

A home-based remote care solution provides sensors including a basic health monitor (BHM) that is a measurement and feedback system. The BHM operates with low power integrated communications combined with an in-home, low power mesh network or programmable digital assistant (PDA) with cell phone technology. A cognitive system allows remote monitoring of the location and the basic health of an individual. The BHM measures oxygen saturation (SaO2), temperature of the ear canal, and motion, including detection of a fall and location within a facility. Optionally, the BHM measures CO2, respiration, EKG, EEG, and blood glucose. No intervention is required to determine the status of the individual and to convey this information to care providers. The cognitive system provides feedback and assistance to the individual while learning standard behavior patterns. An integrated audio speaker and microphone enable the BHM to deliver audio alerts, current measurements, and voice prompts. A remote care provider can deliver reminders via the BHM. The device may be worn overnight to allow monitoring and intervention. Through the ability to inquire, the cognitive system is able to qualify events such as loss of unconsciousness or falls. Simple voice commands activate the device to report its measurements and to give alerts to care providers. Alerts from care providers can be in a familiar voice to assist with compliance to medication regimens and disease management instructions. Simple switches allow volume control and manual activation. The device communicates with a series of low-power gateways to an in-home cognitive server and point-of-care (POC) appliance (computer). Alone the BHM provides basic feedback and monitoring with limited cognitive capabilities such as low oxygen or fall detection. While connected to the cognitive server, full cognitive capabilities are attained. Full alerting capability requires the cognitive server to be connected through an Internet gateway to the remote care provider.

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

A medical digital expert system to predict a patient's response to a variety of treatments (using pre-treatment information) is described. The system utilizes data fusion, advanced signal/information processing and machine learning/inference methodologies and technologies to integrate and explore diverse sets of attributes, parameters and information that are available to select the optimal treatment choice for an individual or for a subset of individuals suffering from any illness or disease including psychiatric, mental or neurological disorders and illnesses. The methodology and system can also be used to determine or confirm medical diagnosis, estimate the level, index, severity or critical medical parameters of the illness or condition, or provide a list of likely diagnoses for an individual suffering/experiencing any illness, disorder or condition.

A method for stimulating a particular area of a brain using a stimulation device includes detecting a spatial structure of a head and determining electrical and/or magnetic properties of at least one part of anatomical structures of the head. An energy amount to be provided by the stimulation device for stimulating the particular area of the brain is calculated automatically based on the spatial structure of the head and the determined electrical and/or magnetic properties of at least one part of the anatomical structures of the head.

Systems and methods for detecting, monitoring, and/or treating neurological events based on, for example, electrical signals generated from the patient's body are disclosed. Various embodiments of the invention include a system for predicting occurrence of a neurological event in a patient's body. The system may include an implant configured to be placed in the body and detect signals indicative of an activity that precedes the neurological event, and a processing unit configured to process the detected signals so as to predict the neurological event prior to the occurrence.

Disclosed is a system and method of assessing the efficacy of treatment of neurological or psychological disorders. The preferred embodiment uses at least two surface electrodes to acquire EEG signals from the surface of a patient's body, a processor for computing from the EEG signals various features and indices that are representative of the patient's neurological or psychological state. Changes in these parameters may be used to assess the efficacy of treatment and to modify the treatment to optimize the resultant patient state.

A system of accessing the brain of a subject to record and/or stimulate brain stares thereof. The system includes control means, first accessing means having a plurality of contact surfaces configured to operatively connect the control means to the brain of the subject to provide three-dimensional stimulation thereof; second accessing means having a plurality of contact surfaces to operatively connect the control means to the brain of the subject to provide access thereto for the purposes of obtaining three-dimensional recordings of the brain electrical activity of the subject; and a waveform bank containing a plurality of stimulating waveforms. The control means is configured to operative apply a first at least one of the stimulating waveforms of the waveform bank to the brain of the subject through the first accessing means and to assess acceptability within defined limits, as determined by preset criteria, of the subject's response to the application of the at first least one of the stimulating waveforms.

The present invention relates to an integrated sleep diagnosis and treatment device, and more particularly to an integrated apnea diagnosis and treatment device. The present invention additionally relates to methods of sleep diagnosis and treatment. The sleep disorder treatment system of the present invention can use a diagnosis device to perform various forms of analysis to determine or diagnose a subject's sleeping disorder or symptoms of a subject's sleep disorder, and using this analysis or diagnosis can with or in some embodiments without human intervention treat the subject either physically or chemically to improve the sleeping disorder or the symptoms of the sleeping disorder. The diagnostic part of the system can use many different types of sensors and methods for diagnosing the severity of the symptoms of or the sleep disorder itself. The treatment part of the system can use a device to physically or chemically treat the subject's symptoms or sleep disorder itself.

A real-time body status monitoring system (RBMS) is presented in this invention. A wearable monitoring apparatus (WMA) worn by users consists of one or a few sensor nodes and a computing module. Sensor nodes communicate with the computing module via either wired or wireless protocols. RBMS incorporates a monitoring center that connects and serves many WMAs. Together with the sensors and context-aware information fusion and analysis, the system in the invention goes beyond sampling rare events that may be of profound diagnostic, prognostic, or therapeutic importance. It measures the physiological responses to therapeutic interventions during daily activities, which constitute direct and practical health indicators for the patient.

A noise-free portable EEG system is provided. The system has hardware and software and can evaluate mental state quantitatively. The quantitative data of mental states and their levels can be applied to various areas of brain-machine interface including consumer products, video game, toys, military and aerospace as well as biofeedback or neurofeedback.