39 results about "Breathing disorders" patented technology

The invention relates to the technical field of medical instruments, in particular to a sleep monitoring system based on a non-invasive brain oxygen saturation monitor, which comprises a monitoring system and is used for synchronously and dynamically monitoring local brain oxygen in real time, and the monitoring system comprises a non-invasive brain oxygen dynamic monitoring unit used for monitoring the brain blood oxygen saturation of a patient in real time by adopting a near infrared spectrum technology; the multi-parameter synchronous analysis unit is used for integrating the brain oxygen data, the electroencephalogram signals, the cerebral blood flow data and the respiratory event indexes; the intelligent risk assessment engine analyzes a brain oxygen change rule based on a deep learning algorithm, and predicts a brain function impairment risk caused by sleep breathing disorder; in the intelligent risk assessment engine, on the basis of a space-time convolutional neural network, brain oxygen time sequence data and spatial distribution characteristics are combined, and a brain hypoxia mode of the OSA patient is recognized; the method has the characteristic of realizing early warning of the brain injury related to sleep breathing disorder through noninvasive brain oxygen monitoring, multi-parameter fusion analysis and intelligent risk assessment.

The present invention discloses a sleep apnea monitoring method, comprising: acquiring EEG signals, EOG signals, and photoplethysmography signals; automatically staging sleep and calculating sleep duration based on the EEG and EOG signals; counting apnea and hypopnea events based on the photoplethysmography signals; and calculating the AHI index based on the calculated sleep duration (ST) and the number of apnea and hypopnea events (BSN). Furthermore, a corresponding head-mounted sleep apnea monitoring system and electronic device are also disclosed. The present invention enables real-time and accurate sleep staging and apnea diagnosis.

Methods and apparatus provide monitoring of a sleep disordered breathing state of a person such as for screening. One or more sensors may be configured for non-contact active and / or passive sensing. The processor(s) (7304, 7006) may extract respiratory effort signal(s) from one or more motion signals generated by active non-contact sensing with the sensor(s). The processor(s) may extract one or more energy band signals from an acoustic audio signal generated by passive non-contact sensing with the sensor(s). The processor(s) may assess the energy band signal(s) and / or the respiratory efforts signal(s) to generate intensity signal(s) representing sleep disorder breathing modulation. The processor(s) may classify feature(s) derived from the one or more intensity signals to generate measure(s) of sleep disordered breathing. The processor may generate a sleep disordered breathing indicator based on the measure(s) of sleep disordered breathing. Some versions may evaluate sensing signal(s) to generate indication(s) of cough event(s) and / or cough type.

A device includes at least one first element in operative relation to at least one target tissue from a set of target tissues to treat sleep disordered breathing, which may include obstructive sleep apnea. The operative relation may include sensing and / or stimulation. The at least one target tissue may comprise diaphragm-related tissue, respiratory tissue-related nerves, and / or upper airway patency-related tissue. Example tissue in the set of target tissues includes hypoglossal nerve, infrahyoid muscle (IHM)-innervating nerve, IHMs, glossopharyngeal nerve, an internal superior laryngeal (iSL) nerve, phrenic nerve, diaphragm, pudendal nerve, among other nerves and muscles. In some example, multiple target tissue may be selected for stimulation and / or sensing.

A method of sleep disordered breathing care using specific patient information for a first patient to determine a probability of a particular collapse pattern for an upper airway and / or a therapy outcome, and based on the determination, performing further evaluative procedures and / or implementing therapy.

The present specification describes a system and method of detecting sleep disordered breathing, that includes acquiring a set of unconditioned sleep test data that includes oximetry data and at least one other physiological sensor data; sampling the set of unconditioned sleep test data; storing the sampled set of unconditioned sleep test data; receiving, through a display, an input indicative of a degree of analyzing to be applied to the sampled set of unconditioned sleep test data; based on said input, applying a corresponding degree of analyzing to the unprocessed sleep test data to generate processed sleep test data; and visually displaying the processed sleep test data.

A system for treating disordered breathing of a human being includes an implantable transvenous stimulation lead having at least one stimulation electrode and a sensor configured to detect activity level of the human being. The system includes an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to cause the energy source and the pulse generator to deliver spaced apart stimulation signals to the at least one stimulation electrode while the activity level of the human being is sufficiently low to be indicative of sleep. Spaced apart stimulation pulses from the electrode are configured to extend a duration of a time of at least one breath being defined as the time from an onset of inhalation to the onset of inhalation of a successive breath.

The application discloses a sleep apnea detection method and system based on transcutaneous carbon dioxide monitoring, and belongs to the technical field of sleep apnea detection. The application integrates a miniaturized transcutaneous carbon dioxide detection module composed of a flexible optical sensor and a multi-channel PPG, a bioimpedance sensor and an accelerometer; a heating module is controlled by a PID algorithm to realize constant temperature, so that non-invasive transcutaneous carbon dioxide detection is ensured; a multi-sensor data fusion system is built to realize synchronous acquisition of physiological parameters; a low-power embedded processing unit is adopted to realize real-time processing and monitoring of physiological multi-modal data. The application also cooperates with a machine learning model and combines TcCO2 fluctuation, SpO2 drop rate and respiratory interval variability to realize real-time identification and early warning of sleep apnea events. The application realizes highly integrated and long-lasting continuous monitoring of respiratory health, and effectively improves the home screening capability of sleep breathing disorders.

The invention relates to the technical field of frame assemblies, and particularly discloses a breathing machine frame assembly for conveying gas, which is used for conveying positive-pressure pressurized breathing gas from a flow generator to an airway of a patient to treat sleep breathing disorders. The first connector is arranged on the forehead of a patient, the second connector is adjacent to the nasal side of the patient, and the first connector and the second connector are connected through the hollow pipeline. The fins are used for being connected with the headband to fix the frame on the face of the patient and comprise a first fin adjacent to the first interface and a second fin adjacent to the second interface; wherein the hollow conduit extends upward from a first nasal side of the patient to a first temporal portion, then extends upward to a forehead, and then extends toward a second temporal portion to a second nasal side, forming a profile that at least partially surrounds the eyes and nose of the patient; a supporting part is arranged on the inner wall of the hollow pipeline and used for preventing the gas conveying device from touching the bottom to seal the pressurized gas flow when the first connector is connected with the gas conveying device.

An apparatus includes an implantable stimulator to treat sleep disordered breathing (SDB) and at least one electrode associated with the stimulator. The apparatus may include a microstimulator including a housing to encapsulate at least stimulation circuitry and a control portion including a therapy manager to control the stimulation circuitry based on at least control information.

The present application relates to the field of medical detection, especially to a kind of medical examination auxiliary device.The medical examination auxiliary device of the present application is connected with two connecting heads respectively fixed with two inner clamping blocks on head pad through fixing belt and elastic belt, hollow passage is arranged in right fixed seat and left fixed seat between the two connecting heads, to avoid interfering with the flow of respiratory airflow, the slight outward expansion extrusion force of inner clamping block is applied to the inner side of children's ala nasi by elastic belt, the airflow detection sensor on the inner clamping block can be easily fixed in the nostril of children, at the same time, the nostril of children is kept in the state of expansion, to ensure that the respiratory airflow in the nasal passage of children flows normally.Improve the technical problem that the existing medical detection device for sleep breathing disorder of children exists when detecting the sleep breathing of children in nasal region, the accuracy of detection is affected due to the interference of children's respiratory patency.

An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic nerve through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.

Examples of the disclosure include a method to aid user monitoring of a disordered breathing treatment, comprising providing, by an application running on a user computing device, a patient-selection screen of a graphical user interface (GUI) on a display device of the user computing device; receiving, via an input field of the patient-selection screen, an input from the user indicative of a selected patient; communicating between the user computing device and a treatment system implanted in the selected patient, responsive to receipt of the input indicative of the selected patient, to transfer patient data from the treatment system to the user computing device; and providing, by the application, a diagnostic reporting and monitoring screen including one or more graphical illustrations indicative of sleep position data for the selected patient in combination with one or more graphical illustrations of other data for the selected patient on the GUI.

The present invention relates to novel diazabicyclically substituted imidazo[1,2-a]pyrimidine derivatives, to methods for producing the same, to the use thereof either alone or in combinations for the treatment and / or prevention of diseases, as well as to their use for preparing medicaments for the treatment and / or prevention of diseases, especially for treatment and / or prevention of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnoea and snoring.

The invention discloses an execution control ability training method and system for children suffering from sleep breathing disorder with cognitive disorder. The training method comprises the steps that an initial difficulty level is acquired, initial parameter configuration is carried out, and a gamification training task is formed; displaying the gamification training task, and recording the answer result of the user to each task test; dynamically adjusting a current task parameter based on a real-time answering result of the user; dynamically switching the current selection rule based on the current task parameter and a preset rule switching logic; wherein the selection rules at least include that the character meaning is the same as the color of the stimulant, the character color is the same as the color of the stimulant, and the physical color of the option is the same as the color of the stimulant; immediate feedback is provided for the user in the task training process of the user; and after the user completes the training, a training result is displayed to the user. The method not only can train the suppression control ability of the user, but also can train the cognitive flexibility of the user based on a multi-rule dynamic switching mechanism.

The present invention relates to a surfactant protein B analog and a synthetic pulmonary surfactant comprising same. A pulmonary surfactant according to one aspect has excellent surface physical properties and thus is useful for treating breathing disorders such as infant respiratory distress syndrome.

An apparatus for treating sleep apnea and other sleeping disorders, including snoring and bruxism, but also mouth cavity hygiene, and also possibly drug delivery is provided. The apparatus comprises a device configured to be installed on a user's teeth to maintain a relative position of the upper and lower jaws, and a holding material. The device comprises at least one back part, such as a first back part, a second back part and connecting portion (if two back parts are provided), the first back part having an upper side and a lower side configured to contact at least one premolar and / or molar of the upper and lower jaws, respectively, of the right side of a user's teeth when the user's teeth are in a substantially closed position, and the second back part having an upper side and a lower side configured to contact at least one premolar and / or molar of the upper and lower jaws, respectively, of the left side of the user's teeth when the user's teeth are in a substantially closed position, the connecting portion connecting the first and second back parts and configured to extend along the front teeth of the user's teeth. The holding material is included in or configured to be applied to the first and second back parts to secure contact of the teeth with the first and second back parts, respectively, by creating an adhesive effect, a vacuum effect, or a mechanical holding effect on the teeth in contact with the first and second back parts, respectively.

The utility model provides a respiratory disorder correction device, in particular to the technical field of respiratory disorder correction, which comprises a towing belt, a first magic tape is sewn on the inner side of the towing belt, a first protection pad is sewn on one side of the first magic tape, according to the respiratory disorder correction device, after a wearer wears the towing belt, the first protection pad is arranged at the jaw of the wearer, and the first magic tape is sewn on the first protection pad. The first protection pad is arranged, so that a wearer can wear the pillow more comfortably, the first protection pad is more convenient to replace or independently clean through the first hook-and-loop fastener, the second protection pad is mounted through the second hook-and-loop fastener, more convenient to replace or independently clean and capable of protecting the afterbrain of the wearer, breathable cotton is made of sound-absorbing sponge, and the pillow is more comfortable to wear. The earmuff has the advantages that the female buckle and the male buckle are connected by a wearer, the earmuff can be fastened, the sound absorption effect can be achieved through the breathable cotton, the earmuff can fall asleep better, the first breathable layer and the second breathable layer are breathable and sweat-absorbent, and the earmuff has good moisture absorption and breathability.

The invention relates to the technical field of voice processing and image recognition, and discloses a target detection-based automatic detection method for snore and apnea events in a human sleep process, which comprises the following steps of: collecting continuous audio data of a sleep scene of a patient; performing de-noising processing on the collected original audio data by using Fourier transform to obtain an effective audio number; dividing the audio data by using the sliding windows, and obtaining the audio data of each sliding window; processing the audio data of each sliding window by using an enhancement algorithm, and improving the amplitude of the audio data in a specific frequency range; converting the enhanced signal into an amplitude oscillogram; training a target detection YOLO model added with a context anchor attention mechanism by using the amplitude oscillogram data set; the model can detect snoring or apnea events and count the number of times, frequency and duration of the events. According to the invention, the sleep breathing disorder condition of the human body can be detected in real time with high precision.

Described herein are novel γ- and δ-propargyl carboxylic acids and esters. The novel compositions are antagonists of CSE and may be used to modulate of the activity of the carotid body, therefore providing therapeutic benefits for sleep-related breathing disorders and related conditions.

An apparatus (100) for treating sleep apnea or other respiratory disorders is provided. The apparatus (100) includes an upper portion (101), a lower portion (102), and a middle portion (103). The upper portion (101) is configured to be placed on at least one tooth of the patient's upper jaw, while the lower portion (102) is configured to be placed on at least one tooth of the patient's lower jaw. The middle portion (103) is configured to connect the upper portion (101) and the lower portion (102) together when the upper portion (101) and the lower portion (102) are placed on the teeth of the patient's upper and lower jaws to maintain a fixed position of the upper and lower jaws. The apparatus (100) also includes at least one fastening member, such as dental floss, a nickel-titanium alloy wire, an elastic band, or the like. The fastening member is configured to engage at least one interdental space of each of the upper and lower jaws to fasten the upper portion (101) and the lower portion (102) to the teeth of the upper and lower jaws, respectively. Thus, the apparatus of the present invention provides an improved oral appliance for treating sleep apnea, particularly obstructive sleep apnea, which is capable of maintaining the upper and lower jaws of the patient in a fixed position to keep the airway unobstructed.

This invention discloses a method for analyzing the physical characteristics of an individual, the method comprising: receiving data generated by one or more sensors of a handheld device, the data indicating structural features of the individual's head, neck, or both; generating a structural profile of the individual's head, neck, or both based at least in part on the data; determining, in response to generating the structural profile, risk factors for the individual to have sleep-disordered breathing, to develop sleep-disordered breathing, or both; and generating recommendations for the individual for a treatment type based at least in part on the structural profile, wherein the recommendations for the treatment type include recommendations for using a mandibular repositioning device, recommendations for using a respiratory therapy device, or both.

Described herein are devices and methods of treating obstructive breathing disorders in a patient. A method may include: attaching an anchor to a dorsal region of a tongue body; applying an external force to the tongue body; and adjusting a magnitude of the external force. In some embodiments, the magnitude of the external force is adjustable across multiple levels based on one or more of: patient comfort, desired therapeutic effect, or patient wake or sleep state. In some embodiments, at least a portion of the external force is directed along an anterior direction. In some embodiments, the external force causes at least one of the following actions: anterior displacement of a portion of the posterior tongue during sleep or reducing posterior displacement of a portion of the tongue during sleep.

A system includes stimulation leads, a signal generator coupled to the stimulation leads, and a controller coupled to the signal generator. The stimulation leads are used to stimulate a nerve and / or a muscle of a user at one or more target locations. The signal generator is configured to generate and deliver a therapy signal comprised of one or more stimulation signals to the one or more target locations via the stimulation leads. The controller is configured to initiate or adjust the therapy signal based at least in part on measured parameters. The system can reduce or eliminate stimulation induced sensation for the user, such as paresthesia and / or stimulation induced discomfort, and can reduce or eliminate stimulation induced awakenings and / or impact to the user's sleep quality. Additionally, the system can modify the therapy signal based on one or more parameters and provide treatment for sleep and / or breathing disorders.

The invention provides a sleep breathing disorder risk assessment method and an early warning device. A sleep apnea assessment scale score and a body quality index are integrated to assess a risk level of a patient suffering from a sleep breathing disorder disease. The invention provides a sleep breathing disorder disease risk assessment method and an early warning device, which are used for solving the problems of nonstandard screening mode, high data collection and analysis difficulty, lack of effective management, heavy workload of medical staff and the like in screening and management of sleep breathing disorder diseases in the prior art.

The application discloses a sleep breathing disorder identification system based on deep learning, comprising an audio signal feature extraction module, a feature processing module, a time-weighted attention mechanism module and a bidirectional long short-term memory network module connected in sequence. The audio signal feature extraction module extracts multi-dimensional audio features; the feature processing module processes the features through convolution and full connection layers; the time-weighted attention mechanism module highlights key moment information; the Bi-LSTM module models forward and backward time sequence dependency relationships and is classified through a full connection layer and a Softmax layer. The device comprises a snoring sound input module, a sound detection module, an embedded module and a data display module, can monitor snoring sound signals in real time, displays the detection results in a graphical interface after processing, realizes efficient and accurate identification of various sleep breathing disorders, overcomes the problems of incomplete feature extraction and low modeling efficiency in the prior art, and improves the accuracy and robustness of the audio signal classification task.