64 results about "Breathing disorders" patented technology

The invention discloses portable sleep breathing disorder monitoring equipment based on electroencephalogram, oxyhemoglobin saturation and electrocardio, and belongs to the technical field of sleep monitoring equipment. The monitoring equipment comprises a wireless sleep monitoring module and a sleep breathing disorder diagnosis module, the wireless sleep monitoring module is used for collecting EEG, SpO2 and ECG signals in the sleep process and transmitting the EEG, SpO2 and ECG signals to the sleep dyspnea diagnosis module in real time for signal processing and analysis. The equipment collects multiple modes directly related to accurate diagnosis of sleep breathing disorder, and huge deviation of evaluation of sleep breathing disorder caused by a single mode is avoided. A sensor for collecting forehead electroencephalogram and oxyhemoglobin saturation is integrated on the flexible circuit board, so that the integration level and portability of the device are higher. A multi-modal fusion algorithm is designed for multi-modal signals collected by equipment, and multi-task and accurate detection of automatic sleep staging and sleep breathing events is achieved.

The invention relates to the technical field of medical instruments, in particular to a sleep monitoring system based on a non-invasive brain oxygen saturation monitor, which comprises a monitoring system and is used for synchronously and dynamically monitoring local brain oxygen in real time, and the monitoring system comprises a non-invasive brain oxygen dynamic monitoring unit used for monitoring the brain blood oxygen saturation of a patient in real time by adopting a near infrared spectrum technology; the multi-parameter synchronous analysis unit is used for integrating the brain oxygen data, the electroencephalogram signals, the cerebral blood flow data and the respiratory event indexes; the intelligent risk assessment engine analyzes a brain oxygen change rule based on a deep learning algorithm, and predicts a brain function impairment risk caused by sleep breathing disorder; in the intelligent risk assessment engine, on the basis of a space-time convolutional neural network, brain oxygen time sequence data and spatial distribution characteristics are combined, and a brain hypoxia mode of the OSA patient is recognized; the method has the characteristic of realizing early warning of the brain injury related to sleep breathing disorder through noninvasive brain oxygen monitoring, multi-parameter fusion analysis and intelligent risk assessment.

An implantable neuromodulation system can include an electrode configured to be disposed at or near a first branch of a hypoglossal nerve of a patient and configured to provide a first electrostimulation therapy to treat a sleep disorder or breathing disorder of a patient. The system can include a sensor configured to provide a sensor signal that includes information about a patient response to the first electrostimulation therapy, information about a patient respiration, or information about one or more other physiologic status indicators for the patient. The sensor signal information can be used to quantify a progression of a breathing disorder for the patient.

The present invention discloses a sleep apnea monitoring method, comprising: acquiring EEG signals, EOG signals, and photoplethysmography signals; automatically staging sleep and calculating sleep duration based on the EEG and EOG signals; counting apnea and hypopnea events based on the photoplethysmography signals; and calculating the AHI index based on the calculated sleep duration (ST) and the number of apnea and hypopnea events (BSN). Furthermore, a corresponding head-mounted sleep apnea monitoring system and electronic device are also disclosed. The present invention enables real-time and accurate sleep staging and apnea diagnosis.

Methods and apparatus provide monitoring of a sleep disordered breathing state of a person such as for screening. One or more sensors may be configured for non-contact active and / or passive sensing. The processor(s) (7304, 7006) may extract respiratory effort signal(s) from one or more motion signals generated by active non-contact sensing with the sensor(s). The processor(s) may extract one or more energy band signals from an acoustic audio signal generated by passive non-contact sensing with the sensor(s). The processor(s) may assess the energy band signal(s) and / or the respiratory efforts signal(s) to generate intensity signal(s) representing sleep disorder breathing modulation. The processor(s) may classify feature(s) derived from the one or more intensity signals to generate measure(s) of sleep disordered breathing. The processor may generate a sleep disordered breathing indicator based on the measure(s) of sleep disordered breathing. Some versions may evaluate sensing signal(s) to generate indication(s) of cough event(s) and / or cough type.

A device includes at least one first element in operative relation to at least one target tissue from a set of target tissues to treat sleep disordered breathing, which may include obstructive sleep apnea. The operative relation may include sensing and / or stimulation. The at least one target tissue may comprise diaphragm-related tissue, respiratory tissue-related nerves, and / or upper airway patency-related tissue. Example tissue in the set of target tissues includes hypoglossal nerve, infrahyoid muscle (IHM)-innervating nerve, IHMs, glossopharyngeal nerve, an internal superior laryngeal (iSL) nerve, phrenic nerve, diaphragm, pudendal nerve, among other nerves and muscles. In some example, multiple target tissue may be selected for stimulation and / or sensing.

A method of sleep disordered breathing care using specific patient information for a first patient to determine a probability of a particular collapse pattern for an upper airway and / or a therapy outcome, and based on the determination, performing further evaluative procedures and / or implementing therapy.

The technology relates to forehead cooling systems configured for use with patient interfaces to aid in treatment of sleeping and breathing disorders. Examples of the technology include fluid cooling systems, such as air and water cooling. Other examples use phase change materials, and thermoelectric coolers. In some examples the forehead cooling systems may be attached to a positioning and stabilising structure.

The present specification describes a system and method of detecting sleep disordered breathing, that includes acquiring a set of unconditioned sleep test data that includes oximetry data and at least one other physiological sensor data; sampling the set of unconditioned sleep test data; storing the sampled set of unconditioned sleep test data; receiving, through a display, an input indicative of a degree of analyzing to be applied to the sampled set of unconditioned sleep test data; based on said input, applying a corresponding degree of analyzing to the unprocessed sleep test data to generate processed sleep test data; and visually displaying the processed sleep test data.

A device (100) for treating sleep apnea or other breathing disorders is provided. The device (100) comprises an upper portion (101), a lower portion (102), and an intermediate portion (103). The upper portion (101) is configured to be placed on at least one tooth of the upper jaw of a patient, and the lower portion (102) is configured to be placed on at least one tooth of the lower jaw of the patient. The intermediate portion (103) is configured to couple the upper and lower portions (101, 102) together to maintain a fixed position of the upper and lower jaws when placed on the teeth of the upper and lower jaws of the patient. The device (100) further comprises at least one fastening member, such as floss, nitinol wire, rubber band or the like. The fastening member is configured to engage at least one interdental space of each of the upper and lower jaws to fasten the upper and lower portions (101, 102) to the teeth of the upper and lower jaws, respectively. The device of the present invention, thus, provides an improved oral appliance for treating sleep apnea, specifically obstructive sleep apnea, that is able to maintain the upper and lower jaws of the patient in a fixed position to keep the airway open.

A system for treating disordered breathing of a human being includes an implantable transvenous stimulation lead having at least one stimulation electrode and a sensor configured to detect activity level of the human being. The system includes an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to cause the energy source and the pulse generator to deliver spaced apart stimulation signals to the at least one stimulation electrode while the activity level of the human being is sufficiently low to be indicative of sleep. Spaced apart stimulation pulses from the electrode are configured to extend a duration of a time of at least one breath being defined as the time from an onset of inhalation to the onset of inhalation of a successive breath.

Described herein are novel γ- and δ-propargyl carboxylic acids and esters. The novel compositions are antagonists of CSE and may be used to modulate of the activity of the carotid body, therefore providing therapeutic benefits for sleep-related breathing disorders and related conditions.

The invention discloses a method for constructing a low-oxygen load variability index of sleep breathing disorder. The method comprises the following steps of: 1, preprocessing data; step 2, extracting a specific fragment of generalized apnea; step 3, nonlinear feature extraction; step 4, calculation of statistical features of specific fragments of generalized apnea; and step 5, combined calculation to obtain a low-oxygen load variability index. According to the method, a new evaluation index for quantifying intermittent hypoxia is constructed, the instantaneous change of SPO2 can be quantified, the area under the corresponding oxygen desaturation curve is calculated, and the severity of intermittent hypoxia is evaluated more accurately.

The application discloses a sleep apnea detection method and system based on transcutaneous carbon dioxide monitoring, and belongs to the technical field of sleep apnea detection. The application integrates a miniaturized transcutaneous carbon dioxide detection module composed of a flexible optical sensor and a multi-channel PPG, a bioimpedance sensor and an accelerometer; a heating module is controlled by a PID algorithm to realize constant temperature, so that non-invasive transcutaneous carbon dioxide detection is ensured; a multi-sensor data fusion system is built to realize synchronous acquisition of physiological parameters; a low-power embedded processing unit is adopted to realize real-time processing and monitoring of physiological multi-modal data. The application also cooperates with a machine learning model and combines TcCO2 fluctuation, SpO2 drop rate and respiratory interval variability to realize real-time identification and early warning of sleep apnea events. The application realizes highly integrated and long-lasting continuous monitoring of respiratory health, and effectively improves the home screening capability of sleep breathing disorders.

The invention relates to the technical field of frame assemblies, and particularly discloses a breathing machine frame assembly for conveying gas, which is used for conveying positive-pressure pressurized breathing gas from a flow generator to an airway of a patient to treat sleep breathing disorders. The first connector is arranged on the forehead of a patient, the second connector is adjacent to the nasal side of the patient, and the first connector and the second connector are connected through the hollow pipeline. The fins are used for being connected with the headband to fix the frame on the face of the patient and comprise a first fin adjacent to the first interface and a second fin adjacent to the second interface; wherein the hollow conduit extends upward from a first nasal side of the patient to a first temporal portion, then extends upward to a forehead, and then extends toward a second temporal portion to a second nasal side, forming a profile that at least partially surrounds the eyes and nose of the patient; a supporting part is arranged on the inner wall of the hollow pipeline and used for preventing the gas conveying device from touching the bottom to seal the pressurized gas flow when the first connector is connected with the gas conveying device.

The present invention relates to a combination of a noradrenaline reuptake inhibitor and α2-Adrenoceptor subtype C (alpha-2C) antagonists, in particular substituted heterocyclic carboxamides of formula (I) for the treatment and / or prophylaxis of sleep-related breathing disorders, preferably obstructive and central sleep apneas and snoring.

An apparatus includes an implantable stimulator to treat sleep disordered breathing (SDB) and at least one electrode associated with the stimulator. The apparatus may include a microstimulator including a housing to encapsulate at least stimulation circuitry and a control portion including a therapy manager to control the stimulation circuitry based on at least control information.

The present invention relates to a combination of selective blockers of TASK-1 and TASK-3 channels, in particular substituted imidazo[1,2-a]pyrimidine and substituted imidazo[1,2-a]pyridine derivatives of formula (I) and muscarinic receptor antagonists for the treatment and / or prophylaxis of sleep-related breathing disorders, preferably obstructive and central sleep apneas and snoring.

A system and method for controlling a sleep breathing disorder (SDB) therapy device. While a subject is undergoing therapy using an SDB therapy device, a signal is obtained and processed that is responsive to a change in sympathetic activity of the subject caused by respiration and baroreceptors of the subject to detect a change in sympathetic activity. For a change in sympathetic activity that exceeds a predetermined threshold, it is determined whether the change is chemoreceptor-induced or baroreceptor-induced. A control signal for controlling the SDB therapy device is generated depending on whether the change is chemoreceptor initiated or baroreceptor initiated.

The present application relates to the field of medical detection, especially to a kind of medical examination auxiliary device.The medical examination auxiliary device of the present application is connected with two connecting heads respectively fixed with two inner clamping blocks on head pad through fixing belt and elastic belt, hollow passage is arranged in right fixed seat and left fixed seat between the two connecting heads, to avoid interfering with the flow of respiratory airflow, the slight outward expansion extrusion force of inner clamping block is applied to the inner side of children's ala nasi by elastic belt, the airflow detection sensor on the inner clamping block can be easily fixed in the nostril of children, at the same time, the nostril of children is kept in the state of expansion, to ensure that the respiratory airflow in the nasal passage of children flows normally.Improve the technical problem that the existing medical detection device for sleep breathing disorder of children exists when detecting the sleep breathing of children in nasal region, the accuracy of detection is affected due to the interference of children's respiratory patency.

An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic nerve through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied.

Examples of the disclosure include a method to aid user monitoring of a disordered breathing treatment, comprising providing, by an application running on a user computing device, a patient-selection screen of a graphical user interface (GUI) on a display device of the user computing device; receiving, via an input field of the patient-selection screen, an input from the user indicative of a selected patient; communicating between the user computing device and a treatment system implanted in the selected patient, responsive to receipt of the input indicative of the selected patient, to transfer patient data from the treatment system to the user computing device; and providing, by the application, a diagnostic reporting and monitoring screen including one or more graphical illustrations indicative of sleep position data for the selected patient in combination with one or more graphical illustrations of other data for the selected patient on the GUI.

The present invention relates to novel diazabicyclically substituted imidazo[1,2-a]pyrimidine derivatives, to methods for producing the same, to the use thereof either alone or in combinations for the treatment and / or prevention of diseases, as well as to their use for preparing medicaments for the treatment and / or prevention of diseases, especially for treatment and / or prevention of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnoea and snoring.

A device (100) for treating sleep apnea or other breathing disorders is provided. The device (100) comprises an upper portion (101), a lower portion (102), and an intermediate portion (103). The upper portion (101) is configured to be placed on at least one tooth of the upper jaw of a patient, and the lower portion (102) is configured to be placed on at least one tooth of the lower jaw of the patient. The intermediate portion (103) is configured to couple the upper and lower portions (101, 102) together to maintain a fixed position of the upper and lower jaws when placed on the teeth of the upper and lower jaws of the patient. The device (100) further comprises at least one fastening member, such as floss, nitinol wire, rubber band or the like. The fastening member is configured to engage at least one interdental space of each of the upper and lower jaws to fasten the upper and lower portions (101, 102) to the teeth of the upper and lower jaws, respectively. The device of the present invention, thus, provides an improved oral appliance for treating sleep apnea, specifically obstructive sleep apnea, that is able to maintain the upper and lower jaws of the patient in a fixed position to keep the airway open.

The invention discloses an execution control ability training method and system for children suffering from sleep breathing disorder with cognitive disorder. The training method comprises the steps that an initial difficulty level is acquired, initial parameter configuration is carried out, and a gamification training task is formed; displaying the gamification training task, and recording the answer result of the user to each task test; dynamically adjusting a current task parameter based on a real-time answering result of the user; dynamically switching the current selection rule based on the current task parameter and a preset rule switching logic; wherein the selection rules at least include that the character meaning is the same as the color of the stimulant, the character color is the same as the color of the stimulant, and the physical color of the option is the same as the color of the stimulant; immediate feedback is provided for the user in the task training process of the user; and after the user completes the training, a training result is displayed to the user. The method not only can train the suppression control ability of the user, but also can train the cognitive flexibility of the user based on a multi-rule dynamic switching mechanism.

The present invention relates to a surfactant protein B analog and a synthetic pulmonary surfactant comprising same. A pulmonary surfactant according to one aspect has excellent surface physical properties and thus is useful for treating breathing disorders such as infant respiratory distress syndrome.

The invention provides an individual case management system for sleep breathing disorder diseases, which comprises an individual case manager terminal and a patient terminal, the individual case manager terminal comprises a data management module, a patient screening module, a patient management module and a system configuration module, and the patient terminal comprises an information exchange module and a health science popularization module. The invention provides an individual case management system for sleep breathing disorder diseases. The system is used for solving the problems that in the prior art, the cognition degree is insufficient, the diagnosis and treatment rate is low, the compliance is low, and a traditional medical mode cannot provide enough individual management and long-term follow-up visit.