101 results about "Sleep disorder breathing" patented technology

Methods and / or devices to deliver pulmonary therapy to treat sleep disordered breathing are disclosed.

A neuromodulation system is provided herein. The system can include a cuff electrode, an electronics package, which can be part of a neuromodulation device; an external controller; a sensor; and a computing device. The neuromodulation device can include an antenna including an upper and a lower coil electrically connected to each other in parallel. The computing device can execute a closed-loop algorithm based on physiological sensed data relating to sleep.

At least some embodiments of the present disclosure are directed to systems and methods for managing sleep disordered breathing (e.g., obstructive sleep apnea) for a patient. A first implantable electrode delivers a first stimulation signal proximate to a first nerve of the patient to stimulate the first nerve and activate at least one first muscle for an upper airway dilation of the person. A second implantable electrode delivers a second stimulation signal proximate to a second nerve to stimulate the second nerve and activate at least one second muscle for a caudal tracheal traction for an upper airway of the person. A stimulation signal generator generates the first and second stimulation signals and coordinates the delivery of the first stimulation signal with the delivery of the second stimulation signal.

There is provided a computer-implemented method for determining sleep misperception of a subject during a sleep session. The method comprises receiving sleep condition information. The sleep condition information comprises at least one of SDB information and insomnia information. The SDB information is representative of a sleep disordered breathing (SDB) condition of the subject based on a number of SDB events of the subject per unit of time. The computer-implemented method comprises receiving sleep quality information representative of a quality of sleep of the sleep session experienced by the subject. The computer-implemented method comprises determining a degree of sleep misperception based on the sleep condition information and the sleep quality information. The sleep misperception is representative of a difference between a subjective total sleep time of the sleep session experienced by the subject and an objective total sleep time of the subject in the sleep session.

Devices and / or methods for treating sleep disordered breathing may include stimulation of a single nerve, multiple nerves, as well as other tissues relating to upper airway patency.

A method of reducing or treating snoring, sleep apnea and other forms of sleep disordered breathing, comprising having a patient in need thereof sleep in contact with or in the proximity of an article containing copper. A fabric having anti-snoring, sleep apnea and other forms of sleep disordered breathing properties, the fabric comprising a copper.

Methods and systems for treating sleep disordered breathing and assessing and improving efficacy of treatment of sleep disordered breathing re disclosed herein. According to some embodiments, the present technology includes a method of treating sleep disordered breathing with a neuromodulation system at least partially implanted in a patient having an airway compromised by an obstruction. The method includes delivering stimulation energy to a target nerve in the patient using an electrode of the neuromodulation system, wherein the target nerve is associated with patency of the airway, receiving sensor data from a sensor arrangement of the neuromodulation system, wherein the sensor data is indicative of airflow in the airway proximal to the obstruction, and assessing efficacy of the stimulation energy based at least in part on the received sensor data.

A patient interface for treating sleep disorder breathing includes a textile tube that also provides support for the seal forming structure. The textile tube includes an inner and outer layer that are joined along seams to form an air chamber or passageway. The textile tube can be pre-shaped so that the textile tube resiliently returns to a pre-determined shape prior to the introduction of pressurized air.

At least some embodiments of the present disclosure are directed to systems and methods for managing sleep disordered breathing (e.g., obstructive sleep apnea) for a patient. An implantable electrode delivers a stimulation signal proximate to a nerve of the patient to stimulate the nerve and activate at least one muscle associated with an airway of the person. A controller generates a set of predicted stimulation settings for the stimulation signal using a trained machine learning model and provides the set of predicted stimulation settings to the stimulation signal generator.

Methods and apparatus provide monitoring of a sleep disordered breathing state of a person such as for screening. One or more sensors may be configured for non-contact active and / or passive sensing. The processor(s) (7304, 7006) may extract respiratory effort signal(s) from one or more motion signals generated by active non-contact sensing with the sensor(s). The processor(s) may extract one or more energy band signals from an acoustic audio signal generated by passive non-contact sensing with the sensor(s). The processor(s) may assess the energy band signal(s) and / or the respiratory efforts signal(s) to generate intensity signal(s) representing sleep disorder breathing modulation. The processor(s) may classify feature(s) derived from the one or more intensity signals to generate measure(s) of sleep disordered breathing. The processor may generate a sleep disordered breathing indicator based on the measure(s) of sleep disordered breathing. Some versions may evaluate sensing signal(s) to generate indication(s) of cough event(s) and / or cough type.

A device includes at least one first element in operative relation to at least one target tissue from a set of target tissues to treat sleep disordered breathing, which may include obstructive sleep apnea. The operative relation may include sensing and / or stimulation. The at least one target tissue may comprise diaphragm-related tissue, respiratory tissue-related nerves, and / or upper airway patency-related tissue. Example tissue in the set of target tissues includes hypoglossal nerve, infrahyoid muscle (IHM)-innervating nerve, IHMs, glossopharyngeal nerve, an internal superior laryngeal (iSL) nerve, phrenic nerve, diaphragm, pudendal nerve, among other nerves and muscles. In some example, multiple target tissue may be selected for stimulation and / or sensing.

A method of sleep disordered breathing care using specific patient information for a first patient to determine a probability of a particular collapse pattern for an upper airway and / or a therapy outcome, and based on the determination, performing further evaluative procedures and / or implementing therapy.

There is provided a computer-implemented method for determining sleep misperception of a subject during a sleep session. The method comprises receiving sleep condition information. The sleep condition information comprises at least one of SDB information and insomnia information. The SDB information is representative of a sleep disordered breathing (SDB) condition of the subject based on a number of SDB events of the subject per unit of time. The computer-implemented method comprises receiving sleep quality information representative of a quality of sleep of the sleep session experienced by the subject. The computer-implemented method comprises determining a degree of sleep misperception based on the sleep condition information and the sleep quality information. The sleep misperception is representative of a difference between a subjective total sleep time of the sleep session experienced by the subject and an objective total sleep time of the subject in the sleep session.

An oral appliance for the treatment of sleep disorder breathing in a patient has a U shaped appliance body with a front section and two arms. The appliance body has an inner wall and an outer wall, and a web interconnects the inner and outer walls forming an upper dental arch receiving channel. The front section of the body has an air inlet opening for taking in air during inhalation. The oral appliance also has an air outlet member with an air outlet and an air flow passageway connecting the air inlet opening with the air outlet.

A patient interface for delivering a flow of air at positive pressure relative to ambient air pressure to an entrance to the patient's airways to ameliorate sleep disordered breathing comprises a seal-forming structure to form a seal with a region of the patient's face surrounding an entrance to the patient's airways, a positioning and stabilising structure to provide a force to hold the seal-forming structure in a therapeutically effective position on the patient's head, and a connector assembly adapted to connect to an air circuit. The connector assembly comprises a loop member removably and releasably secured in an aperture of an attachment region of the patient interface and an elbow assembly connected to the air circuit and repeatedly connectable to and detachable from the loop member. The elbow assembly comprises an elbow member and a clip member. The clip member comprises a structure separate and distinct from the elbow member and is connected to the elbow member and releasably connects the elbow assembly to the loop member, the elbow member forming a seal with the loop member when the elbow assembly and loop member are connected to each other.

The present specification describes a system and method of detecting sleep disordered breathing, that includes acquiring a set of unconditioned sleep test data that includes oximetry data and at least one other physiological sensor data; sampling the set of unconditioned sleep test data; storing the sampled set of unconditioned sleep test data; receiving, through a display, an input indicative of a degree of analyzing to be applied to the sampled set of unconditioned sleep test data; based on said input, applying a corresponding degree of analyzing to the unprocessed sleep test data to generate processed sleep test data; and visually displaying the processed sleep test data.

A system for determining parameters for implantable devices that are designed to electrically stimulate the phrenic nerve to treat sleep disordered breathing is provided. The system may use techniques to automate the identification of the parameters that are needed for the recognition and classification of the input signals as well as their values. The system may use techniques for the optimization of the electrical stimulation therapy that is delivered by the implantable device.

Apparatus and methods, such as with processing apparatus (102), distinguish sleep disordered breathing (SDB) events from a signal generated by, for example, a photoplethysmography (PPG) sensor. Data representing the signal from the sensor may be received and a PPG-based respiratory signal may be derived from data. First and / or second level features may be computed from the respiratory signal. The first and / or second level features may be evaluated, such as in a classifier. Based on the evaluation, an output indication identifying SDB type may be generated. In some implementations, the apparatus, detects SDB event(s) from a PPG signal. Data representing the signal from the PPG sensor may be received. A vasoconstriction event and / or arrhythmia event may be detected from the data. The data representing the PPG signal may be evaluated to generate, based on the evaluation and the detected events of vasoconstriction and / or arrhythmias, an output indication identifying SDB event(s).

At least some embodiments of the present disclosure are directed to systems and methods for managing sleep disordered breathing (e.g., obstructive sleep apnea) for a patient. A first implantable electrode delivers a first stimulation signal proximate to a first nerve of the patient to stimulate the first nerve and activate at least one first muscle for an upper airway dilation of the person. A second implantable electrode delivers a second stimulation signal proximate to a second nerve to stimulate the second nerve and activate at least one second muscle for a caudal tracheal traction for an upper airway of the person. A stimulation signal generator generates the first and second stimulation signals and coordinates the delivery of the first stimulation signal with the delivery of the second stimulation signal.

Disclosed are heat and moisture exchangers for use in treatment of sleep disordered breathing. In some examples the heat and moisture exchangers may be positioned within the plenum chamber of a patient interface, an air circuit connected to the patient interface or within a conduit of a positioning and stabilising structure. In examples the heat and moisture exchanger is configured to provide a pressure drop of less than 5 cm of H2O, when measured at a flow rate of 100 litres per minute, while maintaining a humidity level of inhaled air which is 10 mg / L or greater.

A patient interface to deliver a flow of air at a positive pressure with respect to ambient air pressure to an entrance to the patient's airways to ameliorate sleep disordered breathing includes a frame assembly and a nasal pillows assembly configured to removably and repeatably connect to the frame assembly. The frame assembly and the nasal pillows assembly form at least part of a plenum chamber pressurizable to a therapeutic pressure. The nasal pillows assembly comprises a one-piece construction including a seal-forming structure configured to form a seal with a region of a patient's face surrounding the entrance to the patient's airways and a frame connection structure configured to removably and repeatably connect the nasal pillows assembly to the frame assembly. At least a portion of the nasal pillows assembly is configured to directly contact the superior or upper lip of the patient in use.

A patient interface for treating sleep disordered breathing, the patient interface comprising a positioning and stabilizing structure that provides a force to maintain a seal-forming structure in a therapeutically effective position on a patient's head, the positioning and stabilizing structure comprising: at least a first band portion, a first strap portion connected to each side of the plenum and configured to, in use, cover a side surface of the patient's head and cover a parietal bone and / or occipital bone of the patient's head; and a second strap portion having a pair of ends connected to the first strap portion, each end of the second strap portion connected to the first strap portion in use at a location proximate a respective one of the patient's ears, the second strap portion is configured to cover an upper region of the patient's head in use.

Described herein are novel γ- and δ-propargyl carboxylic acids and esters. The novel compositions are antagonists of CSE and may be used to modulate of the activity of the carotid body, therefore providing therapeutic benefits for sleep-related breathing disorders and related conditions.

A method and system for determining a positional sleep disordered breathing (pSDB) status associated with a respiratory device user is disclosed. Airflow data associated with the user is received. The airflow data is analyzed to identify a first time period of suspected arousal and a second time period of suspected arousal. A first time section between the identified first time period and the identified second time period is determined. The airflow data associated with the determined first time section is analyzed to identify (i) an indication of one or more respiratory events and / or (ii) an indication of one or more therapy events. Based at least in part on the (i) identified indication of one or more respiratory events and / or (ii) identified indication of one or more therapy events, the pSDB status of the user is determined, where the pSDB status is indicative of whether or not the user has pSDB.

Embodiments disclosed herein relate to respiratory interfaces for use in treating various respiratory issues including, but not limited to, sleep disorder breathing (e.g. snoring, sleep apnea), and in other forms of assisted and unassisted respiration. Embodiments disclosed herein further relate to nasal prongs, flanges and valves for use with respiratory interfaces. Embodiments disclosed herein further relate to evaluating patient compliance with a respiratory interface and harvesting energy for the respiratory.

In certain example embodiments, an air delivery system includes a controllable flow generator operable to generate a supply of pressurized breathable gas to be provided to a patient for treatment and a pulse oximeter. In certain example embodiments, the pulse oximeter is configured to determine, for example, a measure of patient effort during a treatment period and provide a patient effort signal for input to control operation of the flow generator. Oximeter plethysmogram data may be used, for example, to determine estimated breath phase; sleep structure information; autonomic improvement in response to therapy; information relating to relative breathing effort, breathing frequency, and / or breathing phase; vasoconstrictive response, etc. Such data may be useful in diagnostic systems.

Devices and / or methods for treating sleep disordered breathing may include stimulation of a single nerve, multiple nerves, as well as other tissues relating to upper airway patency.

Devices and methods are described for continuous and non-invasive sensing of: (1) breathing effort, and (2) cellular oxygen need vs. cellular oxygen supply. The devices configurable for remote patient care configured to monitor one or more of sleep disordered breathing, hypertension, heart failure, pneumonia, asthma, chronic obstructive pulmonary disease (COPD), respiratory distress syndrome (RDS) in premature infants, and acute respiratory distress syndrome (ARDS) in children and adults. Additionally, the devices are configurable to control delivery of therapy.

Methods and systems are provided to improve SDB in a patient suffering therefrom by delivering an electrical neuromodulation signal to at least a target site comprising an efferent fiber of the glossopharyngeal nerve that innervates pharyngeal constrictor muscles or the stylopharyngeus muscle. Methods include further delivering electrical neuromodulation signals to other sites including one or more combinations of the ansa cervicalis, the hypoglossal nerve, the palatoglossus muscle, and / or the palatopharyngeus muscle. The electrical neuromodulation signal delivered to efferent fibers of the glossopharyngeal nerve can be done independent of a detected sensory or input signal that measures the neuromuscular state of the patient's airway.

A device and / or method to provide sleep disordered breathing (SDB) care includes an implant-access incision and / or a sensing element.