61 results about "Implantable Electrodes" patented technology

The invention provides an electroencephalogram synchronous acquisition system compatible with nuclear magnetic resonance. The problem of interference of traditional equipment in a strong magnetic field environment is solved through innovative material selection and structural design. According to the system, a platinum-iridium alloy multi-contact implantable electrode probe is adopted and is matched with a nuclear magnetism compatible electrode wire formed by a silver-plated copper wire core body and a silver-plated nylon shielding layer, so that indoor and outdoor long-distance signal transmission of MRI (Magnetic Resonance Imaging) is realized. The signal acquisition and processing unit integrates a non-magnetic ceramic packaging pre-amplifier and an optical fiber isolation transmission data acquisition card, and is matched with a fan-free design computer, so that the influence of a magnetic field on signal processing is thoroughly avoided. According to the scheme, real-time electroencephalogram monitoring in experimental animal task state functional nuclear magnetism is supported, experiments prove that the signal-to-noise ratio is reduced by 30% or above, the distortion rate is controlled to be 2% or below, the advantages of high biocompatibility, low cost and operability are achieved, and the accuracy and reliability of scientific research data collection are remarkably improved.

The utility model relates to the technical field of nerve stimulation, and discloses an electrode contact, an implantable electrode and a nerve stimulation system. The electrode contact comprises a plurality of contact surfaces, each contact surface can independently serve as a stimulation source, and at least two contact surfaces in the plurality of contact surfaces face different directions, so that the electrode contact has a plurality of stimulation directions. According to the electrode contact scheme provided by the embodiment of the utility model, more stimulation directions can be provided, and the effectiveness and accuracy of nerve stimulation can be improved.

Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body. Temperature sensors positioned to measure the temperature at the electrode elements are also implanted, along with a circuit that collects temperature measurements from the temperature sensors. In some embodiments, an AC voltage generator configured to apply an AC voltage across the plurality of sets of electrode elements is also implanted within the person's body.

The embodiment of the invention discloses a testing device. The testing device comprises a cable, a connecting assembly and a stimulating assembly which are connected in sequence. Wherein the connecting assembly is provided with a limiting groove for limiting and fixing the implantable electrode, a plurality of conductive elastic sheets in conductive connection with the cable are arranged in the limiting groove, and the conductive elastic sheets are used for being detachably and electrically connected with a wire of the implantable electrode, so that the implanted implantable electrode is tested. The stimulation assembly is provided with a conductive probe electrically connected with the cable, and can apply a test electric signal to the nervous tissue to carry out a stimulation reaction test, thereby assisting in accurately confirming the position of the target spot. According to the testing device, the electrode testing function and the nerve stimulation testing function are integrated into a single device, the structure is compact, operation is visual, and the accuracy, smoothness and convenience of an operation are remarkably improved.

The utility model provides a connector, an implantable electrode piece using the connector, an electrode assembly and an implantation device, the connector is used for being connected with the implantable electrode piece and comprises an insulation main body and a conductive terminal connected with the insulation main body; the conductive terminals extend along a first direction and are connected with the insulating main body, so that the electrode piece can be vertically connected with the conductive terminals along a second direction, and the first direction is different from the second direction. According to the connector, the implantable electrode piece using the connector, the electrode assembly and the implantation device, the circuit stability can be effectively improved, and the service life of the electrode is prolonged.

The application provides a connector, an implantable electrode member using the connector, an electrode assembly, an implantable device and a preparation method thereof. The connector is used for connecting with an implantable electrode member and comprises an insulating body and a conductive terminal connected with the insulating body. The conductive terminal extends along a first direction and is connected with the insulating body, so that the electrode member can be connected with the conductive terminal in a vertical type along a second direction, and the first direction is different from the second direction. The connector, the implantable electrode member using the connector, the electrode assembly, the implantable device and the preparation method thereof can effectively improve circuit stability and prolong the service life of the electrode.

This utility model relates to the field of medical devices, and more particularly to an MRI-compatible implantable electrode lead and implantable medical device. The implantable electrode lead includes: a conductive core, which may be single-core or multi-core; an insulating layer covering the conductive core; and a shielding layer covering or embedded within the insulating layer. The shielding layer has a mesh structure and is braided from conductive wires with curved sections. This utility model provides a mesh shielding layer made of a biocompatible, electrically conductive material outside the implantable electrode lead. This shielding layer can shield magnetic fields to prevent the internally protected conductive core from overheating, thereby ensuring the safety of the implantable electrode lead during MRI scanning. Furthermore, the shielding layer has a certain degree of elasticity to accommodate the elastic conductor core.

An implantable medical device includes a plurality of implantable electrodes for sensing and pacing a heart of a patient. The plurality of electrodes includes cardiac conduction system electrodes positionable proximate a portion of a cardiac conduction system of a patient. A computing device includes processing circuitry and is operably coupled to a plurality of implantable electrodes. A computing device monitors a precardiac ejection (HS-PEP) of a heart of a patient. A change in the HS-PEP is determined based on the monitoring. A change in HS-PEP is determined to be greater than or equal to a specified threshold. Delivery of cardiac conduction system pacing therapy to the cardiac conduction system of the patient using the cardiac conduction system electrode is initiated based on the HS-PEP being greater than or equal to a specified threshold.

Presented herein is an electroporation shield configured to be removably coupled to an implantable stimulating assembly that includes one or more stimulation electrodes. The electroporation shield is coupled to stimulating assembly such that the electroporation shield electrically insulates the one or more of the stimulation electrodes from an electroporation electrical field generated by one or more electroporation electrodes coupled to the electroporation shield. The electroporation shield may be coupled to the stimulating assembly in a manner that facilitates removal of the electroporation shield and the one or more electroporation electrodes. After electroporation, without having to remove or reinsert the stimulating assembly, thereby exposing the one or more stimulation electrodes to the cells of the recipient for subsequent delivery of stimulation.

The application belongs to the technical field of neuroelectrophysiology and brain stereotaxy, and provides an implantable electrode pushing and protecting device. The device is provided with a separable electrode protecting assembly and a base assembly fixed on the skull. The electrode does not need to be preformed before leaving the factory, and the electrode can be flexibly driven or replaced in the operation of the electrode protecting assembly without involving the base assembly in contact with the skull. The adjustment and use of the implanted electrode are more flexible and convenient.

The utility model discloses an implantable electrode lead and a nerve stimulation system, and the implantable electrode lead comprises an implantation section implanted in a skull, a connection section connected with the implantation section, and a flexible supporting member. The flexible supporting piece is installed in the connecting section and supports the connecting section in the radial direction of the implantable electrode wire so as to prevent the connecting section from being pressed and deformed, and the flexible supporting piece and the connecting section can be bent synchronously. The implantable electrode lead and the nerve stimulation system are used for preventing the guide wire element from being pressed and deformed, and the service life of the implantable electrode lead is prolonged.

The present invention relates to a deep sEEG electrode for brain intracranial neuronal electrical stimulation, the electrode comprising a temperature sensor to protect brain tissue from undesired local temperature increase due to sustained / chronic intracranial neuronal electrical stimulation, and further comprising a humidity sensor to detect a deviation from a baseline liquid volume and / or pressure value in brain parenchyma. In the stimulation process through the electrode, if one or more temperature values rise to exceed a preset safety limit value, the nerve stimulation / sEEG device can immediately interrupt the ongoing nerve stimulation to protect brain tissue from adverse heat side effects. The detected fluid volume and / or pressure values may be transmitted to a neurostimulation / sEEG device that presents data to a physician / neurosurgeon responsible for sEEG operations for assessing whether the implantable electrode is located at a predetermined location, or partially / fully located in the cerebrospinal fluid space within or outside of the brain parenchyma, and assessing the risk of intracranial bleeding.

The application provides an implantable electrode and an electric field treatment device for intracranial tumor treatment. The implantable electrode for intracranial tumor treatment comprises a flexible electrode, the flexible electrode comprises a flexible base layer and at least one electrode unit arranged on the flexible base layer, at least one end of the flexible base layer is not covered by the electrode unit, and an extension section is formed at the part of the flexible base layer not covered by the electrode unit. The electric field treatment device comprises a control module and the implantable electrode, the control module and the flexible electrode of the implantable electrode are electrically connected to generate an alternating electric field. The flexible electrode can be attached to the surface of a tumor cavity by surface adhesion, and the extension section can extend out of the tumor cavity and be attached to the surface of brain tissue, so that the flexible electrode can be stably fixed in the body. Therefore, the targeting of tumor electric field treatment can be obviously improved, the stability of the electric field in the related area can be improved, the compliance of the patient can be improved, adverse reactions can be reduced, and the treatment effect can be improved as a whole.

The utility model discloses an implantable electrode lead and a nerve stimulation system, and the implantable electrode lead comprises an implantation section implanted into the cranium, an extension section connected with the implantation section, an accommodation channel, and a supporting member. The accommodating channel extends from the extension section to the front end of the implantation section but does not penetrate through the front end of the implantation section; the supporting piece is arranged in the containing channel, and the rigidity of the supporting piece comprises at least two kinds. The electrode lead and the nerve stimulation system are used for simplifying the implantation operation of the implantable electrode lead, improving the deformation resistance of the electrode lead, and further prolonging the use and accommodation of the implantable electrode lead.

The application relates to an FPGA-based implantable electrode Spike signal detection system and method, which uses FPGA to collect brain electrical data signals transmitted by an implantable electrode chip, carries out filtering processing and automatic threshold feature extraction on the collected brain electrical data, completes the Spike extraction task, and sends the processed brain electrical data and the original data to an upper computer through a PCI-E mode. Compared with the prior art, the application adopts FPGA parallel processing data, integrates the Spike signal detection method on the FPGA, greatly reduces the real-time detection speed of the Spike, adopts a filter to pre-process the brain electrical data, can effectively retain Spike effective signals, adopts an automatic threshold feature extraction method, can adaptively extract Spike signals according to brain electrical signal fluctuations, not only reduces the power consumption of the chip, but also guarantees the accuracy of Spike signal extraction.

Systems and methods for ambulatory detection of Q wave-to-T wave (QT) interval prolongation are discussed. A medical-device system comprises a controller circuit and a user interface device. The controller circuit includes a long QT syndrome (LQTS) detector that measures a QT interval from a subcutaneous cardiac signal sensed from a patient using implantable electrodes, and detects an indication of QT prolongation using the measured QT time interval and a programmable threshold received as a user input from the user interface. The control circuit can adjust device operation based on the detected indication of QT prolongation. An output unit can generate a programmable alert of the QT prolongation corresponding to the user input of the programmable threshold.

The current invention relates to a flexible electrode comprising a porous flexible substrate material having a first surface and a second surface diametrically opposed to the first surface; at least one through hole in the porous flexible substrate material, where the at least one through hole extends from the first surface to the second surface, the at least one through hole having an internal surface; a conductive material attached to the first and second surfaces of the porous flexible substrate material, wherein: the at least one through hole is formed such that a first entry hole, having a first entry hole diameter, in the first surface has a larger diameter than a corresponding second entry hole in the second surface, or vice versa, such that the internal surface of the through hole is tapered; the conductive material is also attached to the internal surface of the at least one through hole to provide a continuous conductive film attached to the first and second surfaces, where the first and second surfaces are conductively connected by the conductive material in the at least one through hole; and the conductive material penetrates into the porous flexible substrate to form a mechanical interlock between the conductive material and the porous flexible substrate.

The embodiment of the invention discloses an electrode type judgment method and device, electronic equipment and a storage medium. The method comprises the following steps: in response to a current electrode type input operation of a user on a user interface for an implantable electrode, triggering an impedance measurement operation between contact combinations in the implantable electrode; when the impedance measurement operation is executed, obtaining a current electrode type of the implantable electrode input by the user in the user interface and a current impedance measurement result of the impedance measurement operation; determining a current impedance distribution characteristic corresponding to the current electrode type based on an incidence relation between a preset electrode type and the impedance distribution characteristic and the current electrode type; and determining a current judgment result of the current electrode type based on a preset judgment rule, the current impedance distribution characteristic and the current impedance measurement result. According to the technical scheme of the embodiment of the invention, the accuracy of the electrode type of the implantable electrode can be accurately and conveniently judged, so that a wrong electrode type input by a user can be corrected.

A signal generator (100) for a neurological stimulation system includes a signal generation module (110) connectable to a plurality of implantable electrodes (11-18; 21-28) and configured to provide electrical signals to the plurality of implantable electrodes (11-18; 21-28) for neurological stimulation. The signal generator further includes controller (120) configured to operate the signal generation module (110). The controller (120) is configured to automatically change a stimulation parameter used in stimulation therapy at time intervals or at a trigger.

The invention discloses an electric connector of a minimally invasive implantable electrode, which comprises a male head connecting module, a female head connecting module, a first wire and a second wire, and is characterized in that the male head connecting module is electrically connected with the first wire, and the female head connecting module is electrically connected with the second wire; the first wire comprises a first connecting section, and the first connecting section is a section where the first wire is connected to the male head connecting module; the second wire comprises a second connecting section, and the second connecting section is a section where the second wire is connected to the female head connecting module; the male head connecting module and the female head connecting module can be mutually jointed and electrically connected along a preset direction, and the preset direction is basically perpendicular to the extension direction of the first connecting section / the second connecting section; the male head connecting module and the female head connecting module are jointed to form an assembly body; according to the electric connector, the whole implant does not need to be taken out when the stimulator of the implant is replaced, only the module needs to be separated and taken out of the stimulator, and nervous tissue damage caused by secondary implantation is avoided.

A method of controlling an implanted electrode includes receiving information from an external device; calculating a first region in a body in which the electrode is to be implanted and a second region in which electrode implantation is prohibited, based on the received information; and calculating a plurality of predicted paths through which an electrode is moved based on the first region or the second region, and outputting the plurality of predicted paths.

Implantable electrode assemblies, including implantable electrode assemblies for the brain, and associated systems, devices and methods are disclosed herein. In one embodiment, an electrode shank comprises (i) a plurality of electrodes and (ii) a body extending between a proximal end region and a distal end region opposite the proximal end region. The body can include a plurality of non-conductive layers arranged in a stack. The body can further include a plurality of conductive traces formed on each of the plurality of non-conductive layers. The plurality of electrodes can be disposed on the body, and each of the plurality of conductive traces can extend from the proximal end region to a corresponding one of the plurality of electrodes.

The invention discloses an implant conveying system, a heart rhythm adjusting system and a heart rhythm adjusting method. The implant conveying system comprises a puncture sheath (20) and an implant. The puncture sheath (20) comprises a hollow tube body (12), the implant is arranged in the tube body (12) in a releasable mode, the far end of the tube body (12) is a puncture head (13) which can penetrate into the ventricular muscle and guide the tube body (12) to penetrate through the ventricular muscle, and the length of the tube body (12) can at least extend into the ventricular muscle from the outside through a cardiac apex (4). The implants are implantable electrodes (60, 61, 62, 63, 64, 65 and 66), the electrodes (60, 61, 62, 63, 64, 65 and 66) are implanted through an intracardiac path, and real physiological position pace-making and double-chamber electric synchronization are achieved through program control of the pulse generator (80).

The invention discloses a multi-channel multi-mode active electrode integrated nerve probe chip for an implantable brain-computer interface, which comprises a non-implantable circuit part and an implantable electrode part, wherein the non-implanted circuit part integrates a multi-channel electroneurographic signal detection front end, a chemical signal detection front end, a multi-bit adjustable stimulation circuit, a reconfigurable switch array and digital control logic; the implantable electrode part is of a silicon needle structure, electrical electrodes and chemical electrodes are longitudinally distributed on the surface of the implantable electrode part, and dynamic gating and closed-loop regulation and control are supported. Through the electrode-circuit integrated design, the multi-mode function of synchronous high-precision detection and electrical stimulation output of the electroneurographic signals and the chemical signals is achieved, the problems that in the prior art, the mode is single, and the integration degree is low are solved, and the device has the advantages of being high in channel density and low in noise; 5 [mu] Vrms) and a fast closed-loop response (lt; the method is suitable for acute and long-term brain science research and nerve disease treatment.

The utility model discloses an implantable electrode lead and a nerve stimulation system, comprising a stimulation section used for providing electrical stimulation, a connection section electrically connected with a stimulator, and a middle section connecting the stimulation section and the connection section, the middle section comprises at least one strand of stranded wire, the stranded wire comprises at least one section of first spiral part and at least one section of second spiral part, the first spiral part and the second spiral part are connected through a transition part. Wherein the stranded wires of the first spiral part are spirally wound in a first spiral direction, the stranded wires of the second spiral part are spirally wound in a second spiral direction, and the first spiral direction is opposite to the second spiral direction. According to the implantable electrode wire, induced electromotive force generated in a stimulation loop can be avoided or reduced, nuclear magnetic compatibility is achieved, abnormal heating in a nuclear magnetic environment is avoided, the implantable electrode wire in a working state can be prevented from shifting in the nuclear magnetic environment, and the reliability of the implantable electrode wire is improved. And the reliability of the implantable electrode wire in a nuclear magnetic environment is ensured.

The application provides a multi-conducting elastic implant electrode and a preparation method thereof. The multi-conducting elastic implant electrode comprises an electrode body, the electrode body comprises a plurality of electrode segments, each electrode segment comprises an electrode ring, a clamping column and a connecting column, the electrode ring is sleeved outside the connecting column, the plurality of electrode segments are arranged, the clamping column and the connecting column are sequentially and alternately arranged and fixedly connected, two adjacent clamping columns clamp the electrode ring, and the electrode ring and the clamping column are in sealed arrangement; the clamping column is provided with a through hole penetrating through two end surfaces; each electrode ring is electrically connected with a wire, free ends of the wires pass through the through hole and are located on the same side of the electrode body. The application can improve the flexibility of the implant electrode as a whole and can effectively improve the adaptability of the product implanted in the body.

The invention relates to the technical field of intracranial electroencephalogram signal processing, in particular to an intracranial electroencephalogram multivariable decoding method and system based on sparse logistic regression, and the method comprises the steps: obtaining an intracranial electroencephalogram original signal collected by an implantable electrode, and sequentially carrying out the filtering, power frequency interference removal, bad contact removal and re-reference preprocessing of the intracranial electroencephalogram original signal; calculating energy measurement of a whole brain electrode through time-frequency analysis, and forming three-dimensional feature tensors of a space domain M, a time domain T and a frequency domain F; expanding the three-dimensional feature tensor into a feature matrix based on a multivariate analysis method, and selecting an acceleration path of matrix operation according to a ratio of a dimension D to a sample number N; and performing feature subset selection based on sparse logistic regression, inputting the selected feature subset into a classifier, and generating a neural decoding instruction, thereby solving the problems of large data volume, calculation delay, dimension disaster and low scene generalization in the prior art.

This disclosure provides a method for selecting parameters for stimulation of the thalamus using a deep brain stimulator to treat a motor disorder in a subject, such as paralysis of the upper limb and face muscles. Also provided are methods for treating motor disorder in a subject. Also provided is an implantable electrode lead for neuromodulation and recording, configured to provide targeted stimulation and / or recording to multiple anatomically distinct neural structures, specifically the thalamus, the motor cortex, and optionally, the corona radiata, using a single continuous elongate lead body.

The invention discloses a flexible implantable electrode and a preparation method thereof, and a detection system. The flexible implantable electrode comprises a flexible substrate; the graphitization-like carbon film is located on the flexible substrate, the graphitization-like carbon film is provided with a working electrode pattern, a reference electrode pattern and a counter electrode pattern, and the graphitization-like carbon film is formed by pre-mixing graphene oxide and a polymer precursor and then coating the mixture on the first substrate for carbonization reaction; the catalyst layer is positioned on the working electrode pattern; the enzyme recognition layer is positioned on the catalytic layer; the selective membrane is positioned on the enzyme recognition layer; the ink layer is positioned on the reference electrode pattern; and the salt bridge film layer is positioned on the ink layer. The flexible implantable electrode disclosed by the invention has good biocompatibility, long-term stability, mechanical flexibility and implantation adaptability; the thickness and the structure uniformity are good, and large-scale preparation is facilitated.