30 results about "Implanted electrodes" patented technology

The invention discloses a patient improvement effect analysis method for controlling spinal cord electrical stimulation through an implantable brain-computer interface, and relates to the technical field of medical rehabilitation, and the method comprises the steps: multi-dimensional collaborative data collection: implanting electrodes in a target brain region and below a spinal cord injury segment, installing a detection element at an exoskeleton key part, and carrying out multi-dimensional collaborative data collection; a sensor is attached to a lower limb preset muscle group, electroencephalogram signals, SCS stimulation parameters, EXS motion data and neuromuscular response data are synchronously collected, and time correlation marks are embedded; according to the method, the reliability of motion intention decoding is remarkably improved by adopting a mode of combining multi-source signal preprocessing and a multi-mode intention recognition model, and in the signal preprocessing stage, the self-adaptive filtering algorithm combining Kalman filtering and wavelet threshold denoising is applied, so that the motion intention decoding efficiency is improved. SCS electrical stimulation interference, EXS motor noise and physiological noise in the electroencephalogram signals are effectively removed.

The present disclosure relates to an interventional device for implanting an electrode into a brain through a blood vessel having a blood vessel passage and a blood vessel wall, characterized in that the interventional device comprises: a first guide, a distal end of which is movable distally within the blood vessel passage and establishes a first support point in the blood vessel passage; a second guide, a distal end of which is movable distally within the blood vessel passage through the first guide and establishes a second support point in the blood vessel passage, such that the second guide extends arcuately between the first support point and the second support point; and a puncture set for carrying the electrode, and a distal end of which is movable distally within the blood vessel passage through the first guide and punctures the blood vessel wall in a target puncture region between the first support point and the second support point, thereby implanting the carried electrode into the brain. Furthermore, the present disclosure relates to a medical device.

The application belongs to the technical field of neuroelectrophysiology and brain stereotaxy, and provides an implantable electrode pushing and protecting device. The device is provided with a separable electrode protecting assembly and a base assembly fixed on the skull. The electrode does not need to be preformed before leaving the factory, and the electrode can be flexibly driven or replaced in the operation of the electrode protecting assembly without involving the base assembly in contact with the skull. The adjustment and use of the implanted electrode are more flexible and convenient.

The application provides a cochlear implant, which comprises an implanted electrode, a decoder, a receiving coil, an implanted magnet, an auxiliary coil, an elastic buckle and encapsulating silica gel; the implanted electrode, the decoder and the receiving coil are connected in series in sequence, the receiving coil covers the auxiliary coil, the implanted magnet is installed inside the auxiliary coil, the encapsulating silica gel is wrapped outside the implanted magnet 11, and the elastic buckle holds the implanted magnet in the cochlear implant; the auxiliary coil is provided with a via hole, a stop edge one and a stop edge two; the elastic buckle comprises a buckle encapsulating silica gel and a clamping jaw; the clamping jaw is provided with a stopper, a limit and a supporting leg, and the limit is arranged on the inner side of the supporting leg; the stopper holds the stop edge, and the stopper abuts against the flange side edge. The application has good biological safety and good mechanical strength, the receiving coil is provided with the auxiliary coil, the implanted magnet is rotationally held on the auxiliary coil and is provided with the elastic buckle, the impact resistance of the implanted magnet is improved, the application has the anti-disengagement function, and the firmness and reliability of the implant are ensured.

The invention relates to the technical field of implanted electrodes, in particular to a multi-mode composite neural electrode body, an electrode system and a preparation method. Comprising an insulating substrate, a plurality of electrical detection sites are arranged at the tip of the insulating substrate, and a leading-out bonding pad is arranged at the tail of the insulating substrate; a metal wiring layer; the fluid structure comprises a flow channel inlet, a first flow channel outlet and a second flow channel outlet, the flow channel inlet is a medicine inlet, and the first flow channel outlet is a medicine outlet; and the optical fiber penetrates in from the second flow channel outlet and extends to the first flow channel outlet, and an optical fiber light emitting position is formed at the front end of the optical fiber and penetrates out from the first flow channel outlet. By integrating the leading-out bonding pad, the metal wiring layer and the flow channel structure on the base body, electrical detection, electrical stimulation, optical detection, optical stimulation and drug delivery can be carried out after the slender piercing part pierces the human tissue, the freedom degree of a biological experiment is greatly improved, and a complex experiment scene can be dealt with.

The application discloses a brain electric wire fixing band after intracranial electrode implantation, which effectively solves the problem of inconvenient wire fixation after operation of the patient with implanted electrodes; the brain electric wire fixing band comprises a winding band, a fixing ring is arranged at the left free end of the winding band, the winding band is in a circular ring shape and the right free end of the winding band penetrates through the fixing ring, a positioning air bag is fixed to the inner side of the winding band, connecting rings are respectively fixed to the left and right sides of the upper end of the winding band, a pressing band in the up-down direction is fixed to the middle part of the winding band, two anti-pressure air bags are fixed to the upper end of the winding band and are located between the two connecting rings, the pressing band is located between the two anti-pressure air bags, an inflation device is fixed to the right end of the winding band, the left end of the inflation device is communicated with the positioning air bag through a main air pipe, the upper side of the inflation device is communicated with the right anti-pressure air bag through a secondary air pipe, and the two anti-pressure air bags are communicated through a connecting pipe; the structure is simple, convenient to operate, novel in design and high in practicability.

VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the basal and / or septal region of the left ventricular myocardium of the patient's heart from the triangle of Koch region of the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. The device may be used to provide cardiac therapy, including single or multiple chamber pacing, atrioventricular synchronous pacing, asynchronous pacing, triggered pacing, cardiac resynchronization pacing, or tachycardia-related therapy. A separate medical device may be used to provide some functionality for cardiac therapy, such as sensing, pacing, or shock therapy.

The utility model relates to a spiral electrode implanting device, belong to medical instrument technology or the field of neuroscientific research, spiral electrode implanting device is located on the intracranial blood vessel wall, including a spiral support, electrode wire and developing object, the body of spiral support is a spiral shape, the electrode wire that is provided with on the support body is a spiral shape, the both ends of spiral support are equipped with developing object, the utility model can adopt the way of through blood vessel intervention, implants the electrode, gathers the electric signal, simple structure can realize high degree, electrode and blood vessel wall good adhesion, electrode gathers signal effect good, the cross section is small, can be transported through the small sheath, can reach the far end small blood vessel far end, satisfy brain deep position electrode collection and the electrode implanting requirement of intracranial multiple point (brain area).

A method of controlling an implanted electrode includes receiving information from an external device; calculating a first region in a body in which the electrode is to be implanted and a second region in which electrode implantation is prohibited, based on the received information; and calculating a plurality of predicted paths through which an electrode is moved based on the first region or the second region, and outputting the plurality of predicted paths.

Implantable electrode assemblies, including implantable electrode assemblies for the brain, and associated systems, devices and methods are disclosed herein. In one embodiment, an electrode shank comprises (i) a plurality of electrodes and (ii) a body extending between a proximal end region and a distal end region opposite the proximal end region. The body can include a plurality of non-conductive layers arranged in a stack. The body can further include a plurality of conductive traces formed on each of the plurality of non-conductive layers. The plurality of electrodes can be disposed on the body, and each of the plurality of conductive traces can extend from the proximal end region to a corresponding one of the plurality of electrodes.

Devices and methods of use for introduction and implantation of an electrode as part of a minimally invasive technique. An implantable baroreflex activation system includes a control system having an implantable housing, an electrical lead, attachable to the control system, and an electrode structure. The electrode structure is near one end of the electrical lead, and includes a monopolar electrode, a backing material having an effective surface area larger than the electrode, and a releasable pivotable interface to mate with an implant tool. The electrode is configured for implantation on an outer surface of a blood vessel and the control system is programmed to deliver a baroreflex therapy via the monopolar electrode to a baroreceptor within a wall of the blood vessel.

Implant electrode insertion system (1) for inserting an implant electrode into the cochlea (99), comprising an oct device (2) comprising an oct probe (3) defining an optical axis (A) and configured to be held in a measurement position outside of the cochlea and configured to provide an orientation signal representative for an orientation of the oct probe with respect to a cochlea, measured using optical coherence tomography of light emitted from the probe in the measurement position along the optical axis (A); an implant electrode insertion module (4) connected to the oct device, and configured to be arranged in an insertion position on the basis of the orientation signal; and an alignment unit (5) configured to assist in positioning of the implant electrode insertion module (4) in the insertion position on the basis of the orientation signal; wherein the implant electrode insertion module (4) comprises an electrode guide that defines a guide axis (G), and is configured to, in the insertion position, guide a cochlear implant electrode along the guide axis towards the cochlea, wherein the guide axis (G) is coaxial with the optical axis (A) of the oct device.

The invention relates to the technical field of intracranial electroencephalogram signal processing, in particular to an intracranial electroencephalogram multivariable decoding method and system based on sparse logistic regression, and the method comprises the steps: obtaining an intracranial electroencephalogram original signal collected by an implantable electrode, and sequentially carrying out the filtering, power frequency interference removal, bad contact removal and re-reference preprocessing of the intracranial electroencephalogram original signal; calculating energy measurement of a whole brain electrode through time-frequency analysis, and forming three-dimensional feature tensors of a space domain M, a time domain T and a frequency domain F; expanding the three-dimensional feature tensor into a feature matrix based on a multivariate analysis method, and selecting an acceleration path of matrix operation according to a ratio of a dimension D to a sample number N; and performing feature subset selection based on sparse logistic regression, inputting the selected feature subset into a classifier, and generating a neural decoding instruction, thereby solving the problems of large data volume, calculation delay, dimension disaster and low scene generalization in the prior art.

Provided herein are lead and stylet systems and methods of implanting a lead into the brain using a stylet. The lead may be used for deep brain stimulation (DBS) and may be connected to a skull-mounted implantable pulse generator (IPG) of a deep brain stimulation system. The lead may include a lumen configured to removably receive a stylet to assist in implanting an electrode disposed on the lead into the brain. The lead and stylet systems described herein may allow for a minimum of excess lead length between an implantation site of the lead in the brain and an implantable pulse generator (e.g., implanted in the skull).

This disclosure provides a method for selecting parameters for stimulation of the thalamus using a deep brain stimulator to treat a motor disorder in a subject, such as paralysis of the upper limb and face muscles. Also provided are methods for treating motor disorder in a subject. Also provided is an implantable electrode lead for neuromodulation and recording, configured to provide targeted stimulation and / or recording to multiple anatomically distinct neural structures, specifically the thalamus, the motor cortex, and optionally, the corona radiata, using a single continuous elongate lead body.

This invention relates to the field of intracranial electroencephalogram (EEG) signal processing technology, and particularly to an intracranial EEG multivariate decoding method and system based on sparse logistic regression. The method includes: acquiring raw intracranial EEG signals collected by implanted electrodes; sequentially preprocessing the raw intracranial EEG signals by filtering, removing power frequency interference, removing bad contacts, and rereferencing; calculating the energy metric of the whole-brain electrodes through time-frequency analysis to form a three-dimensional feature tensor with spatial domain M, time domain T, and frequency domain F; expanding the three-dimensional feature tensor into a feature matrix based on multivariate analysis, and selecting an acceleration path for matrix operations based on the ratio of dimension D to the number of samples N; performing feature subset selection based on sparse logistic regression, inputting the selected feature subset into a classifier, and generating neural decoding instructions. This invention solves the problems of large data volume, computational latency, curse of dimensionality, and low scene generalization in existing technologies.

This invention discloses an electromagnetic modulation method for improving the formation of glial scars around implanted electrodes. The method selects at least two electrode channels in an implanted brain-computer interface electrode array as stimulation channels and connects them to an external stimulation driving circuit. By outputting a charge-balanced low-frequency pulse stimulation current, it implements staged modulation of the local tissue around the electrodes at different stages after implantation. Simultaneously, it continuously monitors the electrode-tissue interface impedance and / or the signal-to-noise ratio of neural signals, and performs closed-loop switching between different stimulation parameters based on the monitoring results. This method is drug-free and can utilize bipolar or tripolar current-guided stimulation configurations to regulate the spatial distribution of the local electric field. Combined with the accompanying near-field electromagnetic effect, it provides electromagnetic parameter-dependent long-term modulation of the inflammatory response of microglia and astrocytes at the implantation interface, thereby improving the long-term electrical stability of the implantation interface and extending the lifespan of the implanted electrodes.

The application discloses an implantable brain-computer interface control spinal cord electrical stimulation patient improvement effect analysis method, relates to the technical field of medical rehabilitation, and the method comprises the following steps: multi-dimensional cooperative data acquisition: electrodes are implanted below target brain areas and spinal cord injury segments, detection elements are installed at key positions of exoskeletons, sensors are attached to preset muscle groups of lower limbs, electroencephalogram signals, SCS stimulation parameters, EXS motion data and neuromuscular response data are synchronously collected, and time correlation marks are embedded; by adopting the mode that multi-source signal preprocessing is combined with a multi-modal intention recognition model, the reliability of motion intention decoding is remarkably improved, in the signal preprocessing stage, an adaptive filtering algorithm combining Kalman filtering and wavelet threshold denoising is used, and SCS electrical stimulation interference, EXS motor noise and physiological noise in the electroencephalogram signals are effectively removed.

An interventional device for a tubular body, comprising: a stent switchable between a first state and a second state, the diameter of the stent in the second state being greater than the diameter of the stent in the first state; the at least one puncture part is arranged on the stent, and the puncture part is used for puncturing the wall of the tubular body when the stent is in the second state; the at least one electrode is arranged on the at least one puncture part, and the electrode is used for extending out of the tubular body from the area, punctured by the puncture part, of the wall. By means of the scheme, effective implantation of the electrode can be achieved based on the intervention device, the implanted electrode can make direct contact with the biological tissue target area outside the tubular body, direct and non-barrier signal interaction is achieved, and the signal collecting and stimulation applying effects of the electrode are greatly improved.

The invention discloses an epileptic seizure prediction system based on a subcutaneous implanted electrode and a processing method. Comprising a signal acquisition module, a preprocessing module, a feature extraction module, a prediction analysis module and an early warning module. The signal acquisition module is used for acquiring high-quality electroencephalogram signals through an electrode implanted under the skull skin; the preprocessing module carries out filtering and noise reduction on the signal; the feature extraction module extracts time domain and frequency domain low-level features through a first coding unit, and converts the time domain and frequency domain low-level features into high-level features for representation by using a pre-trained Transform encoder; the prediction analysis module calculates an epileptic seizure risk probability value based on the high-level features; and the early warning module triggers local early warning when the probability value exceeds a threshold. According to the invention, through combination of innovative hardware implantation and an advanced algorithm, high-precision, high-robustness and personalized adaptive epileptic seizure prediction is realized, and an effective early warning time window is provided for a patient.

Implantable electrodes with power delivery wearable for treating sleep apnea, and associated systems and methods are disclosed herein. A representative system includes non-implantable signal generator worn by the patient and having an antenna that directs a mid-field RF power signal to an implanted electrode. The implanted electrode in turn directs a lower frequency signal to a neural target, for example, the patient's hypoglossal nerve. Representative signal generators can have the form of a mouthpiece, a collar or other wearable, and / or a skin-mounted patch.

The invention relates to an intelligent medical instrument, in particular to an electrode anatomy positioning system before intractable epilepsy lesion resection operation, which is used for solving the problems that before resection operation, intracranial electrode contact anatomy attribute judgment is lack of standards, classification depends on artificial experience and is difficult to repeat, and multi-modal images are lack of fusion and quantitative analysis. According to the scheme, brain segmentation is carried out based on a T1w image of a patient before electrode implantation, and each brain region segmentation image is made into a mask image; rigid body registration is carried out based on the brain CT with the implanted electrode and the T1w image, an electrode entry point and a target point are marked, an electrode contact is reconstructed, then the position of the contact is judged according to the coordinates of the electrode contact and the mask image, electrode classification and positioning are achieved, a doctor can conveniently distinguish the source of an intracranial electroencephalogram signal, and then the position of a focus is determined. In addition, the position relation and the metabolism condition of the electrode contacts and the cortex layers of the different brain partitions can be clearly checked by fusing multi-mode images.

The application discloses an electrode implantation tool, wherein the distal end of the electrode is provided with a fixing component, the implantation tool comprises an outer sheath and an inner sheath, the inner sheath comprises an inner sheath tube and a first handle, the outer sheath comprises an outer sheath tube and a second handle, the inner sheath tube can be inserted into the outer sheath tube, the first handle is fixed in the second handle, the inner diameter of the inner sheath tube is smaller than the outer diameter of the fixing component, the inner diameter of the outer sheath tube is larger than the outer diameter of the fixing component, and the other part of the electrode except the fixing component can be inserted into the inner sheath tube. The implantation tool provided by the application has a very small diameter and is suitable for conveying a full-implant peripheral electrode or a percutaneous implant electrode for peripheral nerve stimulation treatment with a small diameter, and is matched with the fixing structure at the distal end of the electrode, so that the electrode can be conveyed into the body and firmly combined and fixed with the human body tissue.

This application relates to a method and apparatus for synchronizing an implantable electrical stimulator with a magnetic resonance imaging (MRI) scan. The method includes: detecting a first time delay between the MRI system and the active implantable medical device using a magnetic field detection strategy, and detecting a second time delay between the active implantable medical device and the MRI system using an electrical stimulation state modulation strategy; acquiring device detection information from a time delay synchronization device, and identifying a current time delay synchronization strategy based on the device detection information; and performing time synchronization processing between the MRI system and the active implantable medical device based on the first time delay and the second time delay, using the current time delay synchronization strategy. This method improves the timeliness of MRI scans for users with implanted electrodes.

In general, devices, systems, and techniques are described for titrating electrical stimulation and monitoring sensed data to guide therapy programming. In one example, a system includes processing circuitry configured to control a medical device to deliver electrical stimulation at different values for at least one parameter that defines the electrical stimulation during a period of time and receive information representative of electrical signals sensed via implanted electrodes during the period of time. The processing circuitry may also be configured to generate characteristic values of the information representative of the electrical signals, determine, based on the characteristic values, a change in the electrical signals that corresponds to one value of the different values for the at least one parameter, and set a parameter limit for the parameter at the one value, wherein subsequent electrical stimulation is at least partially limited by the parameter limit.

1. Name of the designed product: transmitter. 2. Use of the designed product: for controlling and powering subcutaneously implanted electrodes. 3. Design points of the designed product: in shape. 4. Picture or photo best indicating the design points: assembly state diagram.

This invention discloses a method, apparatus, system, medium, and product for generating intracranial electrode lead trajectories. The method includes: acquiring medical imaging data of a patient's brain after intracranial electrode lead implantation; extracting a set of feature points corresponding to the electrode lead from the medical imaging data; selecting a set of target feature points implanted in the patient's cranium from the set of feature points based on the trajectory characteristics of the electrode lead in the patient's cranium, wherein the trajectory characteristics at least indicate that the curvature of the electrode lead in the patient's cranium does not exceed a preset curvature value; and simulating the trajectory of the electrode lead in the patient's cranium based on the set of target feature points. This application utilizes the intracranial trajectory of the electrode lead to accurately identify the intracranial electrode lead portion. Through the points corresponding to the intracranial electrode lead portion, precise three-dimensional visualization rendering of the intracranial electrode lead is performed, enabling doctors to better understand the positional relationship between the intracranial electrode lead and surrounding nerve fiber bundles, which helps doctors optimize programming parameters and improve treatment outcomes.

This invention discloses an integrated fixation system for animal brain-computer interfaces, belonging to the fields of biomedical engineering and animal robotics. It includes a protective helmet that fits snugly against the front of the target animal's head via cushioning pads; an electrode shield positioned above the electrode implantation points on the target animal; and a flexible circuit board disposed inside the protective helmet. The electrode implantation points on the electrode shield are connected to the flexible circuit board via short pins, and the flexible circuit board is connected to a main control device mounted on the back of the target animal via a data bus. This invention absorbs and isolates external impacts step by step, effectively protecting the implanted electrodes and ensuring their long-term stability in place.