12 results about "Intracranial electrodes" patented technology

The utility model discloses an electrode buffering piece and an intracranial electrode fixing device. The electrode buffering piece is used in the intracranial electrode fixing device, and comprises a base which is used for being detachably connected with a skull hole seat which can be mounted at a skull hole; the electrode connecting base is used for being connected with an intracranial electrode, the electrode connecting base is movably connected with the base, and the electrode connecting base has a preset movement range relative to the base. According to the electrode buffering piece, after the electrode connecting base of the electrode buffering piece clamps the intracranial electrode and is installed on the cranial hole base along with the base, when the head of a patient conducts some activities, the electrode buffering piece allows the intracranial electrode to conduct tiny activities relative to the cranial hole base, and therefore the intracranial electrode is prevented from being damaged. Therefore, the part, extending into the cranium, of the intracranial electrode is prevented from being bent when the head of the patient performs some activities, and the use reliability of the intracranial electrode is ensured.

The application provides an intracranial electrode carrying support, belonging to the technical field of neural intervention and brain-computer interface; the intracranial electrode carrying support comprises a support body, the support body is integrally provided with a narrow support part and a signal collecting part, an electrode piece for collecting signals is arranged on the outside of the signal collecting part, and the radial dimension of the narrow support part is smaller than that of the signal collecting part; in operation, the support body in a compressed state is automatically expanded after being delivered to a target position, the narrow support part is used for supporting a narrow part of a blood vessel, and the signal collecting part is used for supporting the electrode piece to fully contact the wall of the blood vessel at a non-narrow part to collect signals; and the application mainly solves the technical problems that the existing intracranial electrode carrying support is unstable in signal collection at a narrow part of a blood vessel and the electrode is easily interfered by deposits at the narrow part.

The application discloses a brain electric wire fixing band after intracranial electrode implantation, which effectively solves the problem of inconvenient wire fixation after operation of the patient with implanted electrodes; the brain electric wire fixing band comprises a winding band, a fixing ring is arranged at the left free end of the winding band, the winding band is in a circular ring shape and the right free end of the winding band penetrates through the fixing ring, a positioning air bag is fixed to the inner side of the winding band, connecting rings are respectively fixed to the left and right sides of the upper end of the winding band, a pressing band in the up-down direction is fixed to the middle part of the winding band, two anti-pressure air bags are fixed to the upper end of the winding band and are located between the two connecting rings, the pressing band is located between the two anti-pressure air bags, an inflation device is fixed to the right end of the winding band, the left end of the inflation device is communicated with the positioning air bag through a main air pipe, the upper side of the inflation device is communicated with the right anti-pressure air bag through a secondary air pipe, and the two anti-pressure air bags are communicated through a connecting pipe; the structure is simple, convenient to operate, novel in design and high in practicability.

The present application discloses a real-time navigation device for intracranial electrode implantation and an imaging method. The device includes: a brain detection ultrasonic probe and a local detection ultrasonic probe; the brain detection ultrasonic probe is installed on a cranial hole ring provided on the brain, and the brain detection ultrasonic probe faces intracranially, wherein the brain detection ultrasonic probe is used to collect first ultrasonic images of a first range of the entire intracranial brain in real time; the local detection ultrasonic probe is arranged at the head end of the trocar cannula core, wherein the trocar cannula core is used to pass through the cranial hole ring and insert an electrode into a predetermined position intracranially; the local detection ultrasonic probe is used to collect second ultrasonic images within a second range near the head end, wherein the size of the second range is smaller than the size of the first range, and the resolution of the second ultrasonic images is higher than that of the first ultrasonic images. The problem in the related art that during intracranial electrode implantation, only static images before and after implantation can be used for navigation, and real-time navigation cannot be performed during the implantation process is solved.

Provided herein is a mesoscopic electrophysiological system including a structural system sized and configured to be attached to a head of a patient and to hold a plurality of intracranial electrode shafts in predetermined positions around the head of the patient, a plurality of mesoscopic intracranial electrode shafts that includes a first plurality of electrode contacts configured to measure local field potentials (LFPs) at a plurality of locations in a brain of a patient, wherein each electrode shaft of the plurality of intracranial electrode shafts includes a second plurality of electrode contacts, and a plurality of guide pins sized and configured to receive the plurality of mesoscopic intracranial electrode shafts positioned therein.

A method for delivering electrical stimulation to alter a cognitive state of a user, the method comprising: monitoring a brain signal from the user via one or more intracranial electrodes implanted in the brain of the user while the user is presented with a stimulus; comparing the brain signal to a testing phase biomarker, wherein the testing phase biomarker is derived from a cognitive test performed on a contributor during a testing phase; delivering electrical stimulation to a brain of the user based on the comparing step to steer the brain of the user towards a high performance cognitive state.

This invention discloses an implantable closed-loop neuromodulation system and method, relating to the field of neuroengineering, aiming to solve the problems of poor electrode adaptability and slow closed-loop response in existing implantable neuromodulation systems. The system includes intracranial electrodes, a one-to-one matching adapter plate for adapting different electrodes, a feedthrough component, and an implantable host fixed to the skull surface. The processing unit within the host decodes neural signals in real time within 10 ms to determine the brain state; if an abnormality is detected, the stimulation output unit selects a pattern from a preset safe stimulation pattern library to generate stimulation commands for intervention. This application achieves multi-electrode adaptation through the adapter plate and millisecond-level closed-loop response through high-speed processing, improving the timeliness and accuracy of intervention and enhancing safety.

The invention belongs to the technical field of medical instrument manufacturing, and particularly relates to a manufacturing method of an intracranial deep electrode device, which comprises the following steps: S1, carrying out laser welding on a macro / micro electrode and a CFX electrode wire, and carrying out laser drilling on a PTFE outer tube; s2, mounting the macro-microelectrode on the PTFE outer tube, and primarily fixing the macro-microelectrode by using a fixing tool; s3, the CFX electrode wire is guided through a mandrel of the corresponding size, and a line sequence is marked after the CFX electrode wire is led out; s4, a new PTFE outer pipe is taken again and installed to be flush with the first outer pipe through the core shaft, in this way, along with internal installation, the size of the PTFE outer pipe is decreased, installation of 15 PTFE outer pipes is completed all the time, and final fixing of the macro electrode and the micro electrode is completed; s5, after the macro electrode and the micro electrode are installed, a Tip electrode is installed on the head, electrode leads are all led out and then welded to a PCB at the rear end, the problem of electromagnetic interference isolation can be effectively solved, and the stability during brain electrode implantation is remarkably improved.

The invention relates to an intelligent medical instrument, in particular to an electrode anatomy positioning system before intractable epilepsy lesion resection operation, which is used for solving the problems that before resection operation, intracranial electrode contact anatomy attribute judgment is lack of standards, classification depends on artificial experience and is difficult to repeat, and multi-modal images are lack of fusion and quantitative analysis. According to the scheme, brain segmentation is carried out based on a T1w image of a patient before electrode implantation, and each brain region segmentation image is made into a mask image; rigid body registration is carried out based on the brain CT with the implanted electrode and the T1w image, an electrode entry point and a target point are marked, an electrode contact is reconstructed, then the position of the contact is judged according to the coordinates of the electrode contact and the mask image, electrode classification and positioning are achieved, a doctor can conveniently distinguish the source of an intracranial electroencephalogram signal, and then the position of a focus is determined. In addition, the position relation and the metabolism condition of the electrode contacts and the cortex layers of the different brain partitions can be clearly checked by fusing multi-mode images.

The invention discloses an intracranial electrode implantation length measuring scale, and belongs to the technical field of measuring tools. The intracranial electrode implantation length measuring scale comprises a fixed scale, a vernier scale and two positioning sliding plates, a fixing groove is formed in the fixed ruler in the left-right direction, and electrode fixing devices are arranged at the positions, located at the two ends of the fixing groove, of the fixed ruler respectively; the positioning sliding plate is slidably arranged on the fixed ruler in the left-right direction, the left side edge of the positioning sliding plate is perpendicular to the fixed groove, and a first locking mechanism is arranged on the positioning sliding plate. The vernier is connected with the positioning sliding plate close to the left end of the fixed ruler, the vernier is parallel to the fixed ruler, the left end of the vernier is flush with the left side edge of the positioning sliding plate, a measuring groove is formed in the vernier in the left-right direction, and the left end of the measuring groove penetrates through the vernier. According to the invention, the implantation length of the intracranial electrode can be quickly measured, measurement errors and calculation errors caused by measurement by using a steel ruler are avoided, and meanwhile, the infection risk caused by back-and-forth switching of the steel ruler between a puncture needle and the to-be-measured electrode is also avoided.

This invention discloses a method, apparatus, system, medium, and product for generating intracranial electrode lead trajectories. The method includes: acquiring medical imaging data of a patient's brain after intracranial electrode lead implantation; extracting a set of feature points corresponding to the electrode lead from the medical imaging data; selecting a set of target feature points implanted in the patient's cranium from the set of feature points based on the trajectory characteristics of the electrode lead in the patient's cranium, wherein the trajectory characteristics at least indicate that the curvature of the electrode lead in the patient's cranium does not exceed a preset curvature value; and simulating the trajectory of the electrode lead in the patient's cranium based on the set of target feature points. This application utilizes the intracranial trajectory of the electrode lead to accurately identify the intracranial electrode lead portion. Through the points corresponding to the intracranial electrode lead portion, precise three-dimensional visualization rendering of the intracranial electrode lead is performed, enabling doctors to better understand the positional relationship between the intracranial electrode lead and surrounding nerve fiber bundles, which helps doctors optimize programming parameters and improve treatment outcomes.

The invention provides an interventional intracranial electrode bearing support, and belongs to the technical field of brain-computer interfaces in medical instruments. The stent comprises a stent body with a radial compression state and an expansion state, the stent body is used for being arranged at the set position of an intracranial blood vessel, a plurality of elastic supporting structures capable of deforming in various directions are arranged on the outer side wall of the stent body at intervals in the circumferential direction and / or the axial direction, and electrode plates are fixedly arranged at the ends, away from the stent body, of the elastic supporting structures; when the support body deforms, the elastic supporting structure is used for buffering deformation force in multiple directions so as to guarantee the position stability of the electrode plates. The electrode bearing support is mainly used for solving the technical problems that according to an existing electrode bearing support, the attaching stability of electrode plates is insufficient, the signal collection quality is affected, and the overall reliability of a system is reduced.