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30 results about "Intracranial electrodes" patented technology

Method and system for cortical stimulation to provide adjunct (ADD-ON) therapy for stroke, tinnitus and other medical disorders using implantable and external components

A method and system for providing rectangular and / or complex electrical pulses to cortical tissues of a patient for providing therapy or alleviating symptoms for at least one of tinnitus, essential tremor (ET) including Parkinson's disease, depression, or for providing improvement of functional recovery following stroke. The intracranial electrodes may be implanted on the dura, or subdurally on the pia mater of the cortical surface. The placement of the electrodes may utilize cortical sensing and / or digital imaging techniques, such as fMRI, MRI, or CT. The pulse generator system comprises implantable and external components. The pulse generator may be an implanted pulse generator (IPG) or an external stimulator coupled with an implanted stimulus-receiver. The IPG may also comprise a rechargeable battery. In one embodiment the pulse generator may also comprise a selected number of predetermined / pre-packaged programs. In one embodiment, the pulse generation may also comprise telemetry means, for remote interrogation and / or programming of said pulse generator utilizing a wide area network, such as the internet.
Owner:BOVEJA BIRINDER R +1

Encephalic electrode individualization locating method based on multimode medical image data fusion

InactiveCN103932796ARealize high-precision individual positioningPrecise positioningDiagnosticsSurgeryDiagnostic Radiology ModalityAnatomical structures
An encephalic electrode individualization locating method based on multimode medical image data fusion relates to the fields of medical instruments and medical image processing and neuroimaging. By means of multimode medical image data including magnetic resonance images, X-ray images and intranperative optical photos, the space position relation of an encephalic electrode and a brain tissue structure is comprehensively measured, a relation between the position of the encephalic electrode and a brain anatomical structure is established, and accurate and fast individualization locating of the encephalic electrode is achieved. The encephalic electrode individualization locating method based on multimode medical image data fusion can be used in the fields of cognitive neuroscience basic research, clinic neurosciences and the like, provide accurate brain space position information for an encephalic electroencephalogram signal, and enhance application value in the aspect of electrophysiological basis research.
Owner:BEIJING NORMAL UNIVERSITY

Method for Determining Locations of Implanted Electrodes with Medical Images

A method for accurate localization and visualization of implanted electrodes, such as implanted intracranial electrodes, is provided. More particularly, a realistic representation of intracranial electrode positions on patient-specific post-implantation MRI brain renderings is obtained. The resulting computer models provide an accurate depiction of electrode locations on three-dimensional brain renderings that are suitable for use in surgical planning of resection boundaries around, for example, epileptic zones. Electrodes placed inter-hemispherically are also visible with this method. In addition, a method for creating electrode “shadows” cast upon the brain model surface is provided. These electrode shadows are useful for estimating cortical areas sampled by iEEG and for locating electrodes that may straddle sulci and contact two adjacent cortical gyri.
Owner:THE MEDICAL COLLEGE OF WISCONSIN INC

Methods and Systems for Using Intracranial Electrodes

The present invention relates to electrode assemblies, neurostimulation systems and methods for implanting and using same. In exemplary embodiments, the electrode includes a body having a conductive contact surface dimensioned and configured to contact a patient's skull; and an electrode head associated with the body. The electrode head is sized for subcutaneous positioning adjacent the subject's skull, and the electrode body is of a length and configured such that the electrode body extends at least partially through the patient's skull but does not contact the patient's dura mater. As these electrodes need not directly contact the brain nor penetrate the dura mater to be effective in neurostimulatory applications, they avoid many of the disadvantages, e.g. increased risk of infection and invasive implantation procedures, associated with conventional electrode design.
Owner:AAKEN LAB

Human-computer interaction type intracranial electrode positioning method and system based on three-dimensional convolution

The invention discloses a human-computer interaction type intracranial electrode positioning method and system based on three-dimensional convolution. The method comprises the following steps: an MRIbrain image is segmented to generate a target area mask image of a detection electrode by combining an MRI three-dimensional brain image before an operation and a CT three-dimensional brain image after the operation; three-dimensional convolution operation is carried out on the registered CT brain image, the target area of the detection electrode is extracted according to the mask image and electrode signal images to be screened are extracted; and the electrode signal images to be screened are screened according to pre-operation embedded electrode information to obtain correct electrode imagesand numbering by man-machine interaction. According to the invention, the distinguishing capability of the electrode images is improved through the convolution operation, the distinguishing degree ofthe intracranial electrode in the CT brain image is effectively improved, the automatic identification of a computer is facilitated, and electrode screening and numbering are carried out through a high-efficiency man-machine interaction means, accurately positioning the coordinates of the intracranial electrode in the human brain is facilitated and the method has the advantages of simple principle, convenient achievement and stable result.
Owner:NAT UNIV OF DEFENSE TECH

Eeg recording device

A device is described, which is fully implantable and records the EEG of a person, where the device comprises a subcranial probe containing one or more electrodes, and an extracranial portion, which includes at least one electrode. The subcranial probe proceeds through an opening in the skull. The intracranial portion comprises a seal, which prevents fluid ingress or egress between the subcranial portion and the extracranial portion. Due to the high electrical resistance of the skull, the seal effectively isolates the extracranial electrode from the intracranial electrodes, making the extracranial electrode an effective ground reference for EEG recording.
Owner:EPIC NEURO INC

Cerebral cortex electrode and magnetic resonance image fusion display method and device

Provided are a cerebral cortex electrode and magnetic resonance image fusion display method and device. The method comprises: (S01) obtaining an MRI image through MRI scanning before a patent is implanted with an intracranial electrode and an implanted CT image through CT scanning after the patent is implanted with an intracranial electrode; (S02), registering the MRI image and the CT image in a same coordinate space; S03, extracting electrode image information in the registered CT image; S04, extracting cerebral cortex tissue image information from the registered MRI image; S05, performing special fusion on the electrode image information and the cerebral cortex tissue image information, and displaying the information after special fusion in a 3-dimension graphic method; and S06,adjusting the effect and angle of3-dimension graphic display, and converting an adjusted result into a required format for outputting and storing. According to the invention, electrode position information can be obtained.
Owner:SHENZHEN SINORAD MEDICAL ELECTRONICS

Systems, methods, and devices for intracranial measurement, stimulation, and generation of brain state models

Provided are systems, methods, and devices for intracranial measurement, stimulation, and generation of brain state models. Systems include a plurality of intracranial electrodes configured to be coupled to a brain of a user. Systems further include an interface configured to obtain measurements from the plurality of intracranial electrodes. Systems include a first processing device including one or more processors configured to generate a plurality of brain state parameters characterizing one or more features of at least one brain state of the user, and a second processing device including one or more processors configured to generate at least one model of the brain of the user based, at least in part, on the plurality of brain state parameters and the measurements. Systems include a controller including one or more processors configured to generate a control signal based on the plurality of brain state parameters and the at least one model.
Owner:STIMSCI INC

Personal brain structure displaying device having intracranial electrodes and its displaying method

InactiveUS20170367608A1Recording effect poorStimulation effect poorElectroencephalographyHead electrodesIntracranial electrodesRadiology
An electrode module is positioned inside an intracranial portion of a human head. Then, it captures brain images of the human head so multiples two dimensional (2D) cross-sectional images are obtained. The electrodes can be seen in one or more 2D cross-sectional images. A brain functional map adjusting portion is provided to obtain the 2D cross-sectional images and then to conduct a proportional deformation process for the images in the brain functional map database. By combining the processed images in the brain functional map database and the 2D cross-sectional images, multiple combined cross-sectional images can be obtained for display. So, the effects of intracranial electrodes are better than the traditional way. In addition, the brain structure information of a patient contains the precise positions of the electrodes and the corresponding brain functional areas.
Owner:CHUNG SHAN MEDICAL UNIV HOSPITAL

Deep intracranial electrode and medical instrument

The invention discloses an intracranial deep electrode and a medical instrument. The intracranial deep electrode comprises an insulating support, a plurality of electrode contacts spaced apart at thefront end of the intracranial deep electrode, an electrically conductive terminal and an electromagnetic induction element, wherien the terminal is connected with the support body, the terminal is positioned at the front end of the support body, the electromagnetic induction element is arranged in the terminal, and the electromagnetic induction element is used for acquiring position information ofthe terminal. In the intracranial deep electrode according to an embodiment of the present invention, the electromagnetic induction element for indicating position information of the end is arrangedin the end, the positional information of such a head can be fed back to an external device through an electromagnetic induction element so that the path of the intracranial deep electrode can be traced, thereby improving the accuracy of determining the position of each brain region through the intracranial deep electrode, thereby improving the accuracy of surgical removal of a lesion (e.g., an epileptic lesion).
Owner:NEUROECHOS MEDICAL SHENZHEN CO LTD

Method and system for localizing implanted intracranial electrode

A method for localizing an intracranial electrode in a subject's brain is provided. The intracranial electrode has at least one electrode contact. The method includes: acquiring a first brain image reconstructed from first image data acquired after electrode-implantation; acquiring a second brain image reconstructed from second image data acquired before the electrode-implantation; co-registering the first brain image and the second brain image to acquire spatial transformation parameters; extracting a first coordinate of the electrode contact from the first brain image; converting the first coordinate into a second coordinate in the second brain image by using the spatial transformation parameters; co-registering the second brain image and a universal brain atlas to define functional zones in the second brain image; and defining a corresponding functional zone where the second coordinate is located. Another alternative method and a system for localizing an intracranial electrode are also provided herein.
Owner:NAT YANG MING CHIAO TUNG UNIV

Method and device for implanting intracranial electrode in arc track

The invention provides a method and device for implanting an intracranial electrode in an arc track. The method and the device are used for obtaining a puncture track with the single electrode passing through multiple intracranial target points. In the method for implanting the intracranial electrode, a radian-fixed arc puncture cannula is used for leading the electrode into the cranium, puncture positioning of the radian-fixed arc puncture cannula is achieved through the guidance of a radian-fixed arc guide cannula, the radian-fixed arc guide cannula is fixed to a positioning tool, the positioning tool is provided with a positioning frame and position-adjustable positioning points, the positioning points are provided with fixing parts, and when the arc guide cannula penetrates through the positioning points and is fixed through the fixing parts, positioning of the arc guide cannula is completed; when the arc guide cannula is positioned, the circumference of the circle where the arc of the arc guide canula is located passes through the multiple intracranial target points. According to the implanting method and the orienting device, the multiple target points are stimulated with the single electrode.
Owner:THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIV

Digital input brain-computer interface system based on SEEG signals

The invention discloses a digital input brain-computer interface system based on SEEG signals. The digital input brain-computer interface system comprises a stimulation presentation module, a signal acquisition module, a model training module and an online data analysis module. The stimulation presentation module presents a P300 electroencephalogram mode of stimulating and inducing the testee in asingle flickering mode; the signal acquisition module is used for acquiring and amplifying intracranial electroencephalogram signals of a testee; the model training module performs classifier training on the training data to obtain a classifier response model; and the online data analysis module analyzes the online data in real time by utilizing the obtained classifier response model and outputsa result. The system provided by the invention can realize a digital input function by decoding intracranial electrode signals. According to the system, the same or higher input accuracy and information transmission rate can be realized by using fewer electrode channels. Brand-new interactive experience is brought to some epileptic patients, an effective way is provided for clinical scientific research, and potential social value is achieved.
Owner:SOUTH CHINA UNIV OF TECH

Methods and systems for using intracranial electrodes

The present invention relates to electrode assemblies, neurostimulation systems and methods for implanting and using same. In exemplary embodiments, the electrode includes a body having a conductive contact surface dimensioned and configured to contact a patient's skull; and an electrode head associated with the body. The electrode head is sized for subcutaneous positioning adjacent the subject's skull, and the electrode body is of a length and configured such that the electrode body extends at least partially through the patient's skull but does not contact the patient's dura mater. As these electrodes need not directly contact the brain nor penetrate the dura mater to be effective in neurostimulatory applications, they avoid many of the disadvantages, e.g. increased risk of infection and invasive implantation procedures, associated with conventional electrode design.
Owner:AAKEN LAB

A device, method and system for locating cerebral cortex functional areas

ActiveCN105662598BImprove accuracyOvercoming the defect of response signal lagDiagnostic recording/measuringSensorsHuman bodyMedicine
The invention provides a device for positioning a cerebral-cortex functional area. The device comprises a reminding screen and an intracranial electrode, and further comprises one or more electromyographic electrodes arranged at movement parts of a subject, electromyographic signals are collected and used for allowing moments of action performing of the subject and staring moments of intracranial brain-electrical signal observing of the subject to be synchronous. The invention further provides a method for positioning the cerebral-cortex functional area. The method includes the steps that starting moments of human-body actions are obtained according to original electromyographic signals, then intracranial brain-electrical signals in the corresponding time periods are obtained, and synchronization of the intracranial brain-electrical signals and human-body signals is achieved; then response variable matrixes are generated according to the intracranial brain-electrical signals, independent variable matrixes are generated according to the human-body signals, and the cerebral-cortex area corresponding to the human-body actions is determined by calculating the correlation between the independent variable matrixes and the response variable matrixes. By means of the technical scheme, synchronization between the human-body actions and the intracranial brain-electrical signals can be well achieved, and the accuracy of follow-up processing can be improved.
Owner:TSINGHUA UNIV

Intracranial electrode module and intracranial electrode implantation device

The embodiment of the invention relates to the technical field of medical equipment, and particularly discloses an intracranial electrode module and an intracranial electrode implantation device.The intracranial electrode module comprises a substrate, at least two electrode sampling point sets and a conductive wire, and the electrode sampling point sets are arranged on the substrate and exposed out of the surface of the substrate; the electrode sampling point group comprises electrode sampling points; the conductive wires are arranged on the substrate and are electrically connected with the electrode sampling points; the intracranial electrode module comprises a sampling part, electrode sampling points are located on the sampling part, and the sampling part can be switched between a gathering state and an unfolding state; in the unfolding state, the sampling part is unfolded to be in a fan shape, the sampling part is provided with a first side and a second side which are oppositely arranged in the radial direction of the sampling part, and the electrode sampling point groups are arranged at intervals in the unfolding circumferential direction of the sampling part; and in the gathering state, the second side is gathered. By means of the mode, the intracranial electrode module can be implanted into the human body in the gathering state and then switched into the unfolding state, and therefore the intracranial electrode module can be implanted into the human body through a bone window smaller than the intracranial electrode module.
Owner:SHINEYARD MEDICAL DEVICE CO LTD

Intracranial electrode and delivery system

A cortical access system for delivering a medical tool into an epidural and / or subdural space and onto a patient's brain tissue through a cranium opening comprises: a turret including a proximal end portion, a distal end portion, and a first channel extending from an entrance opening to an exit opening, the first channel configured to guide the medical tool from the entrance opening to the exit opening for positioning on the patients brain tissue. The medical tool may be an electrode or an endoscope.
Owner:MAYO FOUND FOR MEDICAL EDUCATION & RES

Systems and methods for unitized devices placed at bedside for temporary recording of intracranial eeg

The invention encompasses systems and methods that allow a clinician who is untrained in the art of electroencephalography to insert and functionalize unitized intracranial electrode arrays at the bedside that, by specific design, position ground and reference electrodes in electrically "quiet" locations to record durable, high-fidelity intracortical EEG.
Owner:ICE NEUROSYST INC

Implantation device and intracranial electrode implantation equipment

The embodiment of the invention relates to the technical field of medical instruments and equipment, and particularly discloses an implantation device and intracranial electrode implantation device.The implantation device comprises a shell, a catheter and a driving mechanism, the catheter is arranged on the shell and provided with a through guide hole in the extending direction of the catheter, and the driving mechanism is arranged in the guide hole; the guide pipe comprises a first part and a second part which are connected in sequence, and at least part of the second part is located outside the shell and used for stretching into a planted object; the driving mechanism is arranged on the shell, connected with the second part and used for driving the end, away from the first part, of the second part to be away from or close to the first part so that the second part can be bent or straightened. By means of the mode, the end, away from the first part, of the second part can be driven to be away from or close to the first part, so that the second part is bent or straightened, the implanting angle can be adjusted, and operation of a user is facilitated.
Owner:SHINEYARD MEDICAL DEVICE CO LTD

Cable-shaped sensor with wearing main body

The invention relates to a cable-shaped sensor with a wearing main body. The sensor at least comprises: a plurality of lead wires (1), wherein a first end (1a) of each lead wire (1) is provided with an intracranial electrode (2) for acquiring electroencephalogram data of a patient; and an output electrode (3) which can be arranged on a second end (1b) of each lead wires (1), wherein the output electrode (3) can be coupled to an electroencephalograph (4), so that the electroencephalogram data can be transmitted to the electroencephalograph (4) through the output electrode (3). The cable-shapedsensor also comprises a binding bag (5) which is in a hollow cylinder shape, so that each lead wire (1) of which the first end (1a) and the second end (1b) are both located outside the binding bag (5)can be nested in the binding bag (5), and when being subjected to external force, the lead wires (1) can move along the extending direction of the binding bag (5).
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Intracranial electrode plate

The invention provides an intracranial electrode plate. The intracranial electrode plate comprises a flexible substrate, electrode contacts, electrode pins, leads, bunching pipes and lead connectors, wherein the electrode contacts are arranged on the surface of one side of the flexible substrate; each electrode contact is provided with an electrode pin; the electrode pins are located in the flexible substrate; different electrode pins are connected with one end of different leads in the flexible substrate; an insulating film is arranged on the outer surface of each lead; one end of the bunching pipe is connected with one side of the flexible substrate; the other end of the bunching pipe is sleeved with a plurality of lead connectors; and the other ends of the different leads are connected with the different lead connectors on the bunching pipes. According to the electrode plate provided in the scheme, the flexible substrate material is adopted to relieve extrusion of the electrode plate to cortex, the electrode contacts are fixed in the mode that the electrode contacts are fixed through the electrode pins, the electrode contacts can be fixed, and therefore the time for collecting electroencephalogram signals is prolonged to a certain degree, and the detection precision and resolution are improved.
Owner:SHENZHEN INST OF NEUROSCIENCE

Manufacturing method of intracranial electrode integrated with macro electrode and micro electrode

The invention provides a manufacturing method of an intracranial electrode integrated with macro and micro electrodes. The intracranial electrode integrated with the macro electrode and the micro electrode comprises the macro electrode (1), the micro electrode (2), a sleeve (3) and a wire (4). The wires (4) comprise first-class wires (43) and second-class wires (44); wherein one end of the second-class wire (44) is in the shape of a sphere with an exposed conducting layer, and the microelectrode (2) is formed; the manufacturing method of the intracranial electrode integrated with the macro electrode and the micro electrode comprises the following steps: providing the sleeve (3) with a plurality of through holes (31) in the side wall; connecting one end of the first-class wire (43) to the macro electrode (1); and fixing the macro electrode (1) and the micro electrode (2) on the sleeve (3).
Owner:NEUROECHOS MEDICAL SHENZHEN CO LTD

Human-computer interactive intracranial electrode positioning method and system based on three-dimensional convolution

The invention discloses a human-computer interaction type intracranial electrode positioning method and system based on three-dimensional convolution. The method comprises the following steps: an MRIbrain image is segmented to generate a target area mask image of a detection electrode by combining an MRI three-dimensional brain image before an operation and a CT three-dimensional brain image after the operation; three-dimensional convolution operation is carried out on the registered CT brain image, the target area of the detection electrode is extracted according to the mask image and electrode signal images to be screened are extracted; and the electrode signal images to be screened are screened according to pre-operation embedded electrode information to obtain correct electrode imagesand numbering by man-machine interaction. According to the invention, the distinguishing capability of the electrode images is improved through the convolution operation, the distinguishing degree ofthe intracranial electrode in the CT brain image is effectively improved, the automatic identification of a computer is facilitated, and electrode screening and numbering are carried out through a high-efficiency man-machine interaction means, accurately positioning the coordinates of the intracranial electrode in the human brain is facilitated and the method has the advantages of simple principle, convenient achievement and stable result.
Owner:NAT UNIV OF DEFENSE TECH

Brain implantable device

A system includes intracranial electrodes embedded into a cranium, a deep brain stimulation system embedded into the cranium, a brain implantable device embedded into the cranium, and a pulse generator, the deep brain stimulation system and the brain implantable device linked to the intracranial electrodes and to the pulse generator.
Owner:BROWN UNIVERSITY +1

Intracranial electrode integrated with macro and micro electrodes

The invention provides an intracranial electrode integrated with macro and micro electrodes. The intracranial electrode integrated with the macro and micro electrodes comprises a sleeve (3), a wire (4) is arranged in the sleeve (3), wherein a macro electrode (1) and a micro electrode (2) are integrated on the side wall of the sleeve (3); and the macro electrode (1) and the micro electrode (2) respectively transmit signals received by the macro electrode (1) and the micro electrode (2) outwards through the wire (4). In the axial direction of the sleeve (3), the macro electrode (1) and the micro electrode (2) are spaced from each other and are arranged on the side wall of the sleeve (3) in a mutually insulated manner.
Owner:NEUROECHOS MEDICAL SHENZHEN CO LTD

A Device for Implanting Intracranial Electrodes in an Arc Trajectory

The invention provides a method and device for implanting an intracranial electrode in an arc track. The method and the device are used for obtaining a puncture track with the single electrode passing through multiple intracranial target points. In the method for implanting the intracranial electrode, a radian-fixed arc puncture cannula is used for leading the electrode into the cranium, puncture positioning of the radian-fixed arc puncture cannula is achieved through the guidance of a radian-fixed arc guide cannula, the radian-fixed arc guide cannula is fixed to a positioning tool, the positioning tool is provided with a positioning frame and position-adjustable positioning points, the positioning points are provided with fixing parts, and when the arc guide cannula penetrates through the positioning points and is fixed through the fixing parts, positioning of the arc guide cannula is completed; when the arc guide cannula is positioned, the circumference of the circle where the arc of the arc guide canula is located passes through the multiple intracranial target points. According to the implanting method and the orienting device, the multiple target points are stimulated with the single electrode.
Owner:THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIV

deep intracranial electrodes

The present application relates to the technical field of medical devices, in particular to a deep intracranial electrode, comprising a flexible wire, an electrode contact, a plug and an inelastic sleeve. One end of the flexible wire is connected to the electrode contact, and the other end is connected to the electrode contact. In connection with the plug, the inelastic sleeve can be sleeved on the flexible wire, one end of the inelastic sleeve can be connected with the plug, and the other end can be connected with a fixing nut fixed to the skull. When the deep intracranial electrode is subjected to a pulling force, the fixing nut can block the movement of the inelastic sleeve, thereby preventing the deep intracranial electrode from being pulled out.
Owner:NEUROECHOS MEDICAL SHENZHEN CO LTD

A method and device for fusion display of cerebral cortex electrodes and magnetic resonance images

A method and device for fusion display of cerebral cortex electrodes and magnetic resonance images. The method includes: taking the MRI image obtained by MRI scanning before the patient is implanted with intracranial electrodes and the implanted image obtained by CT scanning after the patient is implanted with intracranial electrodes. Post-CT image (S01); register the MRI image and post-implantation CT image in the same coordinate space (S02); extract electrode image information from the registered CT image (S03); extract the electrode image information from the registered MRI Extract cerebral cortex tissue image information from the image (S04); spatially fuse the electrode image information and cerebral cortex tissue image information, and display the spatially fused information through a three-dimensional visualization method (S05); adjust the effect of the three-dimensional visualization display and angle, and convert the adjusted result into the required format for output and storage (S06). Implementing the method and device for fusion display of cerebral cortex electrodes and magnetic resonance images of the present invention has the following beneficial effects: the position information of the electrodes can be obtained.
Owner:SHENZHEN SINORAD MEDICAL ELECTRONICS
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