37 results about "Cortical surface" patented technology

A cortical surface registration procedure related to a diagnostic or surgical procedure. In one embodiment, the procedure includes the steps of pre-operatively obtaining a first textured point cloud of the cortical surface of a targeted region of a brain of a living subject, intra-operatively obtaining optically a second textured point cloud of the cortical surface of the brain of the living subject, and aligning the first textured point cloud of the cortical surface to the second textured point cloud of the cortical surface so as to register images of the brain of the living subject to the cortical surface of the living subject.

A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and / or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.

An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.

A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and / or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.

The invention discloses a forward osmosis membrane based on interfacial hydrophilic modification, which comprises a separation skin layer on the surface, a porous support layer in the middle and a non-woven fabric support material at the bottom, and is characterized in that the porous support layer and the non-woven fabric There is also a hydrophilic polymer layer between the support materials, and the hydrophilic polymer layer is embedded in the non-woven support material. The material of the non-woven supporting material is polyolefin or polyester. The hydrophilic polymer can also be crosslinked by a crosslinking agent. The present invention, through hydrophilic modification, on the one hand reduces the osmotic resistance of water in the osmosis process and improves the water flux; on the other hand, in the process of phase inversion, because water is more permeable, it is easier to undergo instantaneous phase inversion , forming a large pore structure, increasing the porosity and reducing the tortuosity of the pores, so it can significantly reduce the internal concentration polarization and improve the water flux of the membrane.

An apparatus and method for performing automatic 3D image segmentation and reconstruction of organ structures, which is particularly well-suited for use on cortical surfaces is presented. A brain extraction process removes non-brain image elements, then classifies brain tissue as to type in preparation for a cerebrum segmentation process that determines which portions of the image information belong to specific physiological structures. Ventricle filling is performed on the image data based on information from a ventricle extraction process. A reconstruction process follows in which specific surfaces, such as white matter (WM) and grey matter (GM), are reconstructed.

System for performing fully automatic brain tumor and tumor-aware cortex reconstructions upon receiving multi-modal MRI data (T1, T1c, T2, T2-Flair). The system outputs imaging which delineates distinctions between tumors (including tumor edema, and tumor active core), from white matter and gray matter surfaces. In cases where existing MRI model data is insufficient then the model is trained on-the-fly for tumor segmentation and classification. A tumor-aware cortex segmentation that is adaptive to the presence of the tumor is performed using labels, from which the system reconstructs and visualizes both tumor and cortical surfaces for diagnostic and surgical guidance. The technology has been validated using a publicly-available challenge dataset.

Provided is a multi-layer flexible high-density brain electrode and a preparation method thereof. The multi-layer flexible high-density brain electrode includes a plurality of stacked single-layer electrodes and an isolation layer covering the upper surface of the uppermost single-layer electrode; The single-layer electrode includes a flexible substrate and a plurality of metal electrodes; the flexible substrate is used to be closely attached to the cortical surface layer of the brain, and the metal electrodes are grown on the upper side of the flexible substrate; the metal electrodes It includes contact points, lead wires and lead-out points connected in sequence, the contact points are used to collect physiological signals, the lead wires are used to receive the physiological signals and transmit them to the lead-out points, and the lead-out points are used to connect with external equipment to transmit the physiological signal outward; two adjacent single-layer electrodes are staggered in a direction perpendicular to the stacking direction of the plurality of single-layer electrodes.