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37 results about "Cortical surface" patented technology
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The surface of the human cerebral cortex is a highly folded sheet with the majority of its surface area buried within folds.As such, it is a difficult domain for computational as well as visualization purposes. Key Words: Cortical surface reconstruction, flatten- ing, coordinate systems, atlas.
Adjustable suture-button construct for ankle syndesmosis repair
An adjustable, knotless button / loop construct for fixation of ankle syndesmosis tibio-fibular diastasis and an associated method of ankle repair using the same. The knotless construct comprises a pair of buttons attached to a flexible, continuous, self-cinching, adjustable loop integrated with two splices that are interconnected. The knotless construct is passed through fibular and tibia tunnels and the buttons are secured on the cortical surfaces of tibia and fibula. One of the buttons (for example, an oblong button) is secured on the medial side of the tibia by passing the button and the flexible, adjustable loop though the fibular and tibia tunnels and then flipping and seating the button outside the tibia. The length of the flexible adjustable loop is adjusted so that the second button (for example, a round button) is appropriately secured on the lateral fibula.
Owner:ARTHREX
Adjustable suture-button construct for ankle syndesmosis repair
An adjustable, knotless button / loop construct for fixation of ankle syndesmosis tibio-fibular diastasis and an associated method of ankle repair using the same. The knotless construct comprises a pair of buttons attached to a flexible, continuous, self-cinching, adjustable loop integrated with two splices that are interconnected. The knotless construct is passed through fibular and tibia tunnels and the buttons are secured on the cortical surfaces of tibia and fibula. One of the buttons (for example, an oblong button) is secured on the medial side of the tibia by passing the button and the flexible, adjustable loop though the fibular and tibia tunnels and then flipping and seating the button outside the tibia. The length of the flexible adjustable loop is adjusted so that the second button (for example, a round button) is appropriately secured on the lateral fibula.
Owner:ARTHREX
Method and system for cortical stimulation to provide adjunct (ADD-ON) therapy for stroke, tinnitus and other medical disorders using implantable and external components
A method and system for providing rectangular and / or complex electrical pulses to cortical tissues of a patient for providing therapy or alleviating symptoms for at least one of tinnitus, essential tremor (ET) including Parkinson's disease, depression, or for providing improvement of functional recovery following stroke. The intracranial electrodes may be implanted on the dura, or subdurally on the pia mater of the cortical surface. The placement of the electrodes may utilize cortical sensing and / or digital imaging techniques, such as fMRI, MRI, or CT. The pulse generator system comprises implantable and external components. The pulse generator may be an implanted pulse generator (IPG) or an external stimulator coupled with an implanted stimulus-receiver. The IPG may also comprise a rechargeable battery. In one embodiment the pulse generator may also comprise a selected number of predetermined / pre-packaged programs. In one embodiment, the pulse generation may also comprise telemetry means, for remote interrogation and / or programming of said pulse generator utilizing a wide area network, such as the internet.
Owner:BOVEJA BIRINDER R +1
Osteotomy plate, plate driver and method for their use
ActiveUS20110009866A1Great advantageEasy to insertJoint implantsFastenersEngineeringCortical surface
An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.
Owner:ORTHOHELIX SURGICAL DESIGNS
Apparatus and methods of cortical surface registration and deformation tracking for patient-to-image alignment in relation to image-guided surgery
ActiveUS20050148859A1Facilitate surgical procedureImage analysisSurgical navigation systemsPoint cloudMedicine
Owner:VANDERBILT UNIV
Methods for determining pedicle base circumference, pedicle isthmus and center of the pedicle isthmus for pedicle screw or instrument placement in spinal surgery
A method of determining the pedicle base circumference and the pedicle isthmus to facilitate screw placement in a pedicle of a vertebral body during spinal surgery, comprising providing a series of first lines tangential to the outer cortical surface of the vertebral body in and near the pedicle on a transverse section from a three-dimensional image of the vertebral body, providing a series of second lines extending through the vertebral body in and near the pedicle thereof in perpendicular relation to the series of first lines, identifying the pedicle base circumference as the areas of the outer cortical surface where adjacent second lines are at the greatest angle with respect to one another, and identifying the pedicle isthmus as the areas of the outer cortical surface where the second lines that are opposed to each other are closest to being parallel to one another.
Owner:LEUCADIA 6 LLC
Subdural electrode localization and visualization using parcellated, manipulable cerebral mesh models
ActiveUS10149618B1Accurate placementConvenient recordingElectroencephalographyMedical imagingCortical surfaceBrain section
This invention relates generally to methods for localization and visualization of implanted electrodes and penetrating probes in the brain in 3D space with consideration of functional brain anatomy. Particularly, this invention relates to precise and sophisticated methods of localizing and visualizing implanted electrodes to the cortical surface and / or topological volumes of a patient's brain using 3D modeling, and more particularly to methods of accurately mapping implanted electrodes to the cortical topology and / or associated topological volumes of a patient's brain, such as, for example, by utilizing recursive grid partitioning on a manipulable virtual replicate of a patient's brain. This invention further relates to methods of surgical intervention utilizing accurate cortical surface modeling and / or topological volume modeling of a patient's brain for targeted placement of electrodes and / or utilization thereof for surgical intervention in the placement of catheters or other probes into it.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Methods and apparatus for determining brain cortical thickness
Methods and apparatus for determining brain cortical thickness. One method includes determining an intensity profile at each of a plurality of cortical surface points of an imaged brain using brain tissue image data and calculating a cortical thickness based on a parametrically determined transition point of each intensity profile.
Owner:GENERAL ELECTRIC CO +1
Method and a system for optimizing the configuration of multisite transcranial current stimulation and a computer-readable medium
A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and / or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
Owner:BETH ISRAEL DEACONESS MEDICAL CENT INC +1
Osteotomy plate, plate driver and method for their use
An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.
Owner:ORTHOHELIX SURGICAL DESIGNS
Automatic 3D segmentation and cortical surfaces reconstruction from t1 MRI
An apparatus and method for performing automatic 3D image segmentation and reconstruction of organ structures, which is particularly well-suited for use on cortical surfaces is presented. A brain extraction process removes non-brain image elements, then classifies brain tissue as to type in preparation for a cerebrum segmentation process that determines which portions of the image information belong to specific physiological structures. Ventricle filling is performed on the image data based on information from a ventricle extraction process. A reconstruction process follows in which specific surfaces, such as white matter (WM) and grey matter (GM), are reconstructed.
Owner:SONY CORP
Osteotomy plate, plate driver and method for their use
An orthopedic plate is specifically configured for use in osteotomies, in which part of the plate extends into a portion of a first bone segment and part is external to the cortical surface of an adjacent bone segment to fix the segments to allow them to fuse. The plate has a first end and a second end where the end which is inserted into the bone has a chamfer and a through hole having a hole axis optionally at an oblique angle to the longitudinal axis of the plate, and which can receive a screw, peg or pin. The second end of the plate includes a locking screw hole and optionally including a compression slot extending in a direction toward a screw hole in the opposing end. Optionally, the non-locking hole has a shroud that forms an arc or portion of a cylinder over the hole. A plate driver having a recess that holds the plate is used to insert the plate into the bone.
Owner:ORTHOHELIX SURGICAL DESIGNS
Method and system for trackerless image guided soft tissue surgery and applications of same
Methods and systems for performing trackerless image guided soft tissue surgery. For a patient in need of brain surgery, pre-operative preparation for a patient is performed by generating a three-dimensional textured point cloud (TPC) for the patient's scalp surface, and registering the first three-dimensional TPC to a magnetic resonance (MR) model of the brain. During the surgery, an intra-operative cortical surface registration to the MR model is performed for the MR-to-cortical surface alignment. Then shift measurement and compensation to the MR model is performed by: performing absolute deformation measurement of the brain based on the MR model with the cortical surface registration, and obtaining shift correction to the MR model using the absolute deformation measurements. The shift correction may be used for adjusting an image guidance system (IGS) in the brain surgery.
Owner:VANDERBILT UNIV
Super-resolution anatomical magnetic resonance imaging using deep learning for cerebral cortex segmentation
Super-resolution images are generated from standard-resolution images acquired with a magnetic resonance imaging (“MRI”) system. More particularly, super-resolution (e.g., sub-millimeter isotropic resolution) images are generated from standard-resolution images (e.g., images with 1 mm or coarser isotropic resolution) using a deep learning algorithm, from which accurate cortical surface reconstructions can be generated.
Owner:THE GENERAL HOSPITAL CORP
Method and apparatus for estimating degree of neuronal impairment in brain cortex
InactiveUS20020107455A1Improve reliabilityHigh sensitivityElectroencephalographySensorsNeuronal damageNeuronal degeneration
The neuronal activity in the brain of demented subject becomes non-uniform over the cortical surface and this non-uniformity is sensitively detected by properly analyzing observed scalp potentials. The present invention is related to the computer algorithm and apparatus for numerically detecting the degree of such neuronal degeneration. A proper frequency component of EEG is selected so that its scalp potential becomes smooth in a normal subject. When the brain function is impaired, non-uniformity of neuronal activity is detected in spatial as well as temporal fluctuations in the observed scalp potential of properly filtered EEG (usually the alpha component). The statistical parameters derived from dipolarity values of such a properly selected EEG component determine the state of the brain, in which whether the subject is normal or demented is Judged in the early stage of dementia by comparing the obtained parameters with their threshold values. This invention presents a reliable, inexpensive, easy-to-handle and non-invasive method for sensitive screening of dementia and monitoring progress of dementia which also allows optimizing medication and treatment for dementia.
Owner:BRAIN FUNCTIONS LAB
System and Method for Hemi Knee Replacement for Tibial Plateau Fracture
InactiveUS20140207242A1Immediate weight-bearing capabilitiesPromote osteogenesisJoint implantsKnee jointsArticular surfacesArticular surface
The present invention provides a prosthetic implant for partial replacement of an anatomical part. The implant includes a unitary body with a generally flat lower end face for supporting the body on a cortical surface, a generally curved exterior side face and a generally flat upper end face. A modular bearing plate disposed on the upper end face includes an upper articular surface for supporting articulation of an anatomical surface and an opposed mounting surface in contact with the upper end face. A fixation bracket includes a first end coupled to the exterior side face of the body and a second end projecting downward past the lower end face of the body with a contour generally corresponding to an outer surface of an anatomical part. The prosthetic implant is configured to replace a portion of the outer surface of the anatomical part and extend partially into the anatomical part.
Owner:VRAHAS MARK
Methods for determining pedicle base circumference, pedicle isthmus and center of the pedicle isthmus for pedicle screw or instrument placement in spinal surgery
A method of determining the pedicle base circumference and the pedicle isthmus to facilitate screw placement in a pedicle of a vertebral body during spinal surgery, comprising providing a series of first lines tangential to the outer cortical surface of the vertebral body in and near the pedicle on a transverse section from a three-dimensional image of the vertebral body, providing a series of second lines extending through the vertebral body in and near the pedicle thereof in perpendicular relation to the series of first lines, identifying the pedicle base circumference as the areas of the outer cortical surface where adjacent second lines are at the greatest angle with respect to one another, and identifying the pedicle isthmus as the areas of the outer cortical surface where the second lines that are opposed to each other are closest to being parallel to one another. The center of the pedicle isthmus is identified from a cross-section thereof as the intersection of two lines derived from the centers of infinitesimal orthogonal second perpendicular lines from the outer cortical surface.
Owner:LEUCADIA 6 LLC
Adaptive layered neighborhood radius method for abnormal brain tissue case classification
InactiveCN106023030AFully explore the relevanceEliminate noise interferenceData processing applicationsPatient-specific dataPattern recognitionMedical record
The invention discloses an adaptive layered neighborhood radius method for classifying abnormal brain tissue medical records, which comprises the following steps: first constructing a four-layer structural segmentation framework based on the adaptive neighborhood radius, and assigning each layer to a neighborhood The effective solution of the radius is to adaptively adjust the neighborhood radius through iterative calculations; then, the interaction of the neighborhood radius within the same layer and the cascade operation of the neighborhood radius between different layers are performed on the medical records of abnormal brain tissue. The present invention can effectively extract the attribute characteristics of different regions inside the medical records of abnormal brain tissue, improve the classification efficiency of different longitudinal cortical surface labels of brain tissue, and have good effects on early prevention of abnormal brain diseases and delaying the onset of brain diseases.
Owner:NANTONG UNIVERSITY
Intramedullary compression rod
ActiveUS9622798B2Reduce harmStabilizing a fracture of a boneInternal osteosythesisJoint implantsIntramedullary rodFemur intramedullary nailing
A device and method of stabilizing a fracture of a bone is provided. The device includes an intramedullary rod having a shaped distal end, and an insertion jig detachably connectable to the proximal end of the rod and used with the rod to apply a compressive force to the fracture site. The jig may also be used to correctly place fixation screws in a proximal end of the rod. The device achieves both fixation of the rod to the bone regardless of rod or bone diameter and allows for compression at the fracture site. In addition, fixation of the rod to the bone is accomplished without requiring a precise alignment of a distal end fixation screw. The device uses headless fixation screws, which, when in place, are disposed below cortical surface of bone, reducing damage to overlying soft tissues.
Owner:MERRELL GREGORY
Methods for localization and visualization of electrodes and probes in the brain using anatomical mesh models
ActiveUS20190175020A1Accurate placementConvenient recordingElectroencephalographyMedical imagingBrain sectionCortical surface
This invention relates generally to methods for localization and visualization of implanted electrodes and penetrating probes in the brain in 3D space with consideration of functional brain anatomy. Particularly, this invention relates to precise and sophisticated methods of localizing and visualizing implanted electrodes to the cortical surface and / or topological volumes of a patient's brain using 3D modeling, and more particularly to methods of accurately mapping implanted electrodes to the cortical topology and / or associated topological volumes of a patient's brain, such as, for example, by utilizing recursive grid partitioning on a manipulable virtual replicate of a patient's brain. This invention further relates to methods of surgical intervention utilizing accurate cortical surface modeling and / or topological volume modeling of a patient's brain for targeted placement of electrodes and / or utilization thereof for surgical intervention in the placement of catheters or other probes into it.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Method and a system for optimizing the configuration of multisite transcranial current stimulation and a computer-readable medium
A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and / or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
Owner:BETH ISRAEL DEACONESS MEDICAL CENT INC +1
A kind of forward osmosis membrane based on interface hydrophilic modification and preparation method thereof
ActiveCN105195027BReduce penetration resistanceReduce tortuositySemi-permeable membranesPolyesterPolyolefin
The invention discloses a forward osmosis membrane based on interfacial hydrophilic modification, which comprises a separation skin layer on the surface, a porous support layer in the middle and a non-woven fabric support material at the bottom, and is characterized in that the porous support layer and the non-woven fabric There is also a hydrophilic polymer layer between the support materials, and the hydrophilic polymer layer is embedded in the non-woven support material. The material of the non-woven supporting material is polyolefin or polyester. The hydrophilic polymer can also be crosslinked by a crosslinking agent. The present invention, through hydrophilic modification, on the one hand reduces the osmotic resistance of water in the osmosis process and improves the water flux; on the other hand, in the process of phase inversion, because water is more permeable, it is easier to undergo instantaneous phase inversion , forming a large pore structure, increasing the porosity and reducing the tortuosity of the pores, so it can significantly reduce the internal concentration polarization and improve the water flux of the membrane.
Owner:OCEAN UNIV OF CHINA +1
Automatic 3D segmentation and cortical surfaces reconstruction from T1 MRI
An apparatus and method for performing automatic 3D image segmentation and reconstruction of organ structures, which is particularly well-suited for use on cortical surfaces is presented. A brain extraction process removes non-brain image elements, then classifies brain tissue as to type in preparation for a cerebrum segmentation process that determines which portions of the image information belong to specific physiological structures. Ventricle filling is performed on the image data based on information from a ventricle extraction process. A reconstruction process follows in which specific surfaces, such as white matter (WM) and grey matter (GM), are reconstructed.
Owner:SONY CORP
System of joint brain tumor and cortex reconstruction
System for performing fully automatic brain tumor and tumor-aware cortex reconstructions upon receiving multi-modal MRI data (T1, T1c, T2, T2-Flair). The system outputs imaging which delineates distinctions between tumors (including tumor edema, and tumor active core), from white matter and gray matter surfaces. In cases where existing MRI model data is insufficient then the model is trained on-the-fly for tumor segmentation and classification. A tumor-aware cortex segmentation that is adaptive to the presence of the tumor is performed using labels, from which the system reconstructs and visualizes both tumor and cortical surfaces for diagnostic and surgical guidance. The technology has been validated using a publicly-available challenge dataset.
Owner:SONY CORP
Methods for determining pedicle base circumference, pedicle isthmus and center of the pedicle isthmus
A method of determining the pedicle base circumference and the pedicle isthmus to facilitate screw placement in a pedicle of a vertebral body during spinal surgery, comprising providing a series of first lines tangential to the outer cortical surface of the vertebral body in and near the pedicle on a transverse section from a three-dimensional image of the vertebral body, providing a series of second lines extending through the vertebral body in and near the pedicle thereof in perpendicular relation to the series of first lines, identifying the pedicle base circumference as the areas of the outer cortical surface where adjacent second lines are at the greatest angle with respect to one another, and identifying the pedicle isthmus as the areas of the outer cortical surface where the secondlines that are opposed to each other are closest to being parallel to one another. The center of the pedicle isthmus is identified from a cross-section thereof as the intersection of two lines derived from the centers of infinitesimal orthogonal second perpendicular lines from the outer cortical surface.
Owner:LEUCADIA 6 LLC
Neural interrogation platform
ActiveUS20200038651A1Easily and simultaneously accessReduces surgical implantation site limitationSpinal electrodesHead electrodesDura materEngineering
A system includes spatially isolated nodes proximal to a cortical surface or spinal cord, a telemetric antenna array located above the dura, the telemetric antenna array configured to provide power to and exchange data with the spatially isolated nodes, and a power and data distribution unit configured to power the spatially isolated nodes, aggregate recorded data, send the aggregated recorded data and commands through a wireless link.
Owner:BROWN UNIVERSITY
Multi-layer flexible high-density brain electrode and preparation method thereof
ActiveCN111202518BAvoid interferenceAccurately elicitDiagnostic recording/measuringSensorsHigh densityCortical surface
Owner:TSINGHUA UNIV
Methods and apparatus for determining brain cortical thickness
Methods and apparatus for determining brain cortical thickness are provided. One method includes determining an intensity profile at each of a plurality of cortical surface points of an imaged brain using brain tissue image data and calculating a cortical thickness based on a parametrically determined transition point of each intensity profile.
Owner:GENERAL ELECTRIC CO +1
Super-resolution anatomical magnetic resonance imaging using deep learning for cerebral cortex segmentation
Super-resolution images are generated from standard-resolution images acquired with a magnetic resonance imaging (“MRI”) system. More particularly, super-resolution (e.g., sub-millimeter isotropic resolution) images are generated from standard-resolution images (e.g., images with 1 mm or coarser isotropic resolution) using a deep learning algorithm, from which accurate cortical surface reconstructions can be generated.
Owner:THE GENERAL HOSPITAL CORP
Neural interrogation platform
ActiveUS11464964B2Reduce restrictionsControl damageSpinal electrodesHead electrodesDura materCortical surface
A system includes spatially isolated nodes proximal to a cortical surface or spinal cord, a telemetric antenna array located above the dura, the telemetric antenna array configured to provide power to and exchange data with the spatially isolated nodes, and a power and data distribution unit configured to power the spatially isolated nodes, aggregate recorded data, send the aggregated recorded data and commands through a wireless link.
Owner:BROWN UNIVERSITY
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