Surgical guide development based on
anatomical surface topology analysis includes determining
surface shape variability of a surface of bony
anatomy in a
region of interest, generating, based on the
surface shape variability, a digital guide design of a proposed surgical guide for use against the bony
anatomy during a surgical procedure, the generating determining placement and surface coverage for the proposed surgical guide and configuring the proposed surgical guide to have a corresponding
footprint and guide features configured to interface with selected features of the surface of the bony
anatomy, rating the proposed surgical guide for use against the bony anatomy during the surgical procedure by performing, using the digital guide design, an automated topology-based
stability assessment to produce a performance rating for the proposed surgical guide, determining whether the performance rating for the proposed surgical guide satisfies a predefined performance rating threshold, and performing
processing based on that determination.