10784results about "Tomography" patented technology

Improved novel 3D imaging and reconstruction methods for quantitative and accurate 3D imaging used in multiple industries, segments, and applications within each. Improvement includes methods and hardware configured to improve performance and lower radiation and improve accessibility. Using simplified system matrix and datasets of little scatter interference in tomographic image acquisition and reconstruction, in some cases, using time continuity and spatial continuity to generate parameter data for substances within VOI for a number of key applications in medical and non-medical fields.

This application is directed to systems, methods, and devices for image based analysis of plaque. In some embodiments, the approaches herein can be used for developing treatment plans, which can include local treatment, systemic treatment, or both. In some embodiments, the approaches herein can be used for stent selection. In some embodiments, the approaches herein can be used for surgical planning, which can include robotic surgical planning. In some embodiments, the approaches herein can be used for image normalization. In some embodiments, the approaches herein can be used for identifying plaque calcification thresholds. In some embodiments, the approaches herein can be used for identifying thin cap fibroatheroma. In some embodiments, the approaches herein can be used for coronary artery tree reconstruction. Some embodiments are directed to coronary artery disease risk stratification.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and / or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and / or dynamically identify one or more features, such as plaque and vessels, and / or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and / or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and / or quantified parameters.

The invention relates to the technical field of assessment and early warning systems, and particularly discloses a rectal cancer operation risk assessment and early warning system based on multi-modal data fusion, which comprises a multi-modal data acquisition module, a data preprocessing module, a cross-modal fusion module, a dynamic risk assessment module, an intelligent early warning module and a system self-checking module. By integrating multi-modal data and dynamically allocating weights, real-time risk updating in the whole operation period is achieved, the comprehensiveness, timeliness and precision of risk assessment are comprehensively improved by combining the grading early warning function, the autonomous detection calibration function and the risk tracing and countermeasure matching function, long-term reliable operation of the system is guaranteed, powerful support is provided for clinical decision making, and the risk assessment method is suitable for clinical decision making. The surgical risk and the complication occurrence rate are effectively reduced.

Various embodiments described herein relate to systems, devices, and methods for non-invasive image-based plaque analysis and risk determination. In particular, in some embodiments, the systems, devices, and methods described herein are related to analysis of one or more regions of plaque, such as for example coronary plaque, using non-invasively obtained images that can be analyzed using computer vision or machine learning to identify, diagnose, characterize, treat and / or track coronary artery disease.

A robotic surgical system includes a robotic manipulator configured to perform surgical procedures under direct surgeon control. A surgical camera system captures real-time intraoperative video. An external imaging interface receives multimodal imaging data, including preoperative and intraoperative data from at least one of magnetic resonance imaging (MRI), computed tomography (CT), ultrasound, and fluoroscopy. An artificial intelligence (AI module has a trained neural network and a deep learning model trained on multi-institutional annotated surgical datasets, The AI module is configured to execute one or more of: fuse acquired video and imaging data into temporally and spatially coherent anatomical visualizations; generate continuously updating overlays aligned with the surgical field, with segmented anatomical features; projected tissue boundaries, proximity indicators for instruments, and predictive deformation trends; provide dynamic predictive trend visualization indicating zones of future anatomical complexity or risk; register and align preoperative imaging data with intraoperative imaging data in real time; adapt overlay presentation in response to tissue deformation without actuating the robotic manipulate or; and passively augment visual feedback without initiating any autonomous actuation of surgical instruments.

Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of a location of disease in the patient's vasculature based on the received patient-specific data; identifying one or more changes in geometry of the anatomic model based on a modeled progression or regression of disease at the location; calculating one or more values of a blood flow characteristic within the patient's vasculature using a computational model based on the identified one or more changes in geometry of the anatomic model; and generating an electronic graphical display of a relationship between the one or more values of the calculated blood flow characteristic and the identified one or more changes in geometry of the anatomic model.

A computer-implemented method for processing medical images may comprise: receiving image data for a patient; based on the received image data, determining: a patient-specific epicardial adipose tissue (EAT) metric or a patient-specific pericoronary adipose tissue (PCAT) metric, and at least one other patient-specific metric, and using the EAT metric or the PCAT metric, and the at least one other patient-specific metric, to determine a risk score for the patient or to classify a disease state of the patient.

A computer-implemented method for processing medical images may comprise: receiving image data for a patient; based on the received image data, determining: a patient-specific epicardial adipose tissue (EAT) metric or a patient-specific pericoronary adipose tissue (PCAT) metric, and at least one other patient-specific metric, and using the EAT metric or the PCAT metric, and the at least one other patient-specific metric, to determine a risk score for the patient or to classify a disease state of the patient.

An apparatus, system, and method are disclosed for remediating a condition present in a patient's foot. In some implementations, a resection guide includes a bone engagement feature configured to engage at least a portion of at least one foot bone to position the resection guide. The bone engagement feature may be least partially determined based on a model of the patient's foot, which is defined based on medical imaging of the patient's foot. The resection guide further includes a resection feature that extends through the resection guide from a superior side of the resection guide to an inferior side. The resection feature is configured to guide a cutting tool to form a first osteotomy in a first bone along a first trajectory. Additionally, the resection guide includes a first bone attachment feature configured to engage the first bone and a second bone attachment feature configured to engage a second bone.

An apparatus for performing a vascular assessment is disclosed. The apparatus creates a three-dimensional model that is representative of a coronary vessel tree of a patient based on at least two angiographic images. The apparatus estimates first blood flow resistance values for points along at least some vascular segments of the coronary vessel tree using vascular geometrical dimensions of the three-dimensional model. The apparatus also estimates second blood flow resistance values for the points along the at least some vascular segments of the coronary vessel tree using a volume of a crown of the vascular segment downstream from the respective point. The apparatus determines fractional flow reserve (“FFR”) by calculating a ratio of the first blood flow resistance values and the second blood flow resistance values at each of the points along the at least some vascular segments of the coronary vessel tree.

Systems and methods are disclosed for to determining a blood supply and blood demand. One method includes receiving a patient-specific model of vessel geometry of at least a portion of a coronary artery, wherein the model is based on patient-specific image data of at least a portion of a patient's heart having myocardium; determining a coronary blood supply based on the patient-specific model; determining at least a portion of the myocardium corresponding to the coronary artery; determining a myocardial blood demand based on either a mass or a volume of the portion of the myocardium, or based on perfusion imaging of the portion of the myocardium; and determining a relationship between the coronary blood supply and the myocardial blood demand.

Systems and methods are disclosed for evaluating a patient with vascular disease. One method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of a location of disease in the patient's vasculature based on the received patient-specific data; identifying one or more changes in geometry of the anatomic model based on a modeled progression or regression of disease at the location; calculating one or more values of a blood flow characteristic within the patient's vasculature using a computational model based on the identified one or more changes in geometry of the anatomic model; and generating an electronic graphical display of a relationship between the one or more values of the calculated blood flow characteristic and the identified one or more changes in geometry of the anatomic model.

This application is directed to systems, methods, and devices for image based analysis of plaque. In some embodiments, the approaches herein can be used for developing treatment plans, which can include local treatment, systemic treatment, or both. In some embodiments, the approaches herein can be used for stent selection. In some embodiments, the approaches herein can be used for surgical planning, which can include robotic surgical planning. In some embodiments, the approaches herein can be used for image normalization. In some embodiments, the approaches herein can be used for identifying plaque calcification thresholds. In some embodiments, the approaches herein can be used for identifying thin cap fibroatheroma. In some embodiments, the approaches herein can be used for coronary artery tree reconstruction. Some embodiments are directed to coronary artery disease risk stratification.

The invention relates to the technical field of medical instrument control, in particular to a lung biopsy sampling needle stabilizing method and system based on dynamic respiration compensation. The stabilizing method comprises the following steps: acquiring a respiratory movement signal of a patient in real time through a multi-source biosensor, wherein the multi-source biosensor comprises an optical fiber strain sensor array, a diaphragm myoelectricity sensor and a respiratory airflow sensor which are deployed at the chest and abdomen. According to the method, millimeter-microsecond-level accurate and stable control over the lung biopsy sampling process is achieved by establishing a cooperation mechanism of a breathing phase-displacement nonlinear mapping model and a macro-micro composite driving framework. The biological rationality of displacement prediction is improved through deep coupling of multi-mode breathing signals, and the chest wall non-uniform deformation gradient is analyzed in space based on cross topology deployment of an optical fiber strain sensor in an intercostal space area in combination with cross-scale feature fusion of myoelectricity and airflow sensing.

The invention provides an hemorrhagic brain injury intracranial pressure prediction and early warning system based on a CT image, and the system comprises a data collection module which is used for collecting the original data of a target data source of a target patient; the hybrid model comprises a 3DCNN model used for extracting hematoma spatial features of the head CT image sequence; the LSTM model is used for extracting hematoma time sequence characteristics of the physiological signals; the multi-modal fusion module is used for fusing the hematoma space features and the hematoma time sequence features and outputting hematoma fusion features; the prediction module is used for predicting an ICP sequence of the target patient in a future preset time period based on the hematoma fusion features; the self-adaptive early warning module is used for outputting a visual result based on the predicted ICP sequence in the future preset time period; and through a dynamic threshold adjustment mechanism, adjusting an early warning threshold of the target patient in combination with the case information, and triggering graded early warning in real time. Through personalized data processing and dynamic early warning, accurate, efficient and real-time patient risk management is realized.

Technology is described for augmenting medical imaging for use in a medical procedure. The method can include the operation of receiving an image of patient anatomy captured by a visual image camera during the medical procedure. An acquired medical image associated with the patient anatomy can then be retrieved. Another operation can be associating the acquired medical image to the patient anatomy. An augmentation tag associated with a location in one layer of the acquired medical image can be retrieved. A further operation can be projecting the acquired medical image and the augmentation tag using an augmented reality headset to form a single graphical view as an overlay to the patient anatomy in either 2D, 3D or holographic form.

There is provided a method and a system for generating a 3D parametric mesh of an anatomical structure of a patient for storing multi-domain data therein. A plurality of anatomical segments having been obtained from segmentation of a set of images of a patient are received. A 3D mesh comprising a plurality of concentric 3D mesh layers is received, where each concentric 3D mesh layer includes a same predetermined number of nodes. A set of nodes in the 3D mesh corresponding to a respective anatomical segment is determined to obtain a respective correspondence rule therebetween. The set of nodes is encoded with a set of features from the respective anatomical segment by using the correspondence rule to obtain a 3D parametric mesh, each node of the set of nodes in the 3D parametric mesh being associated with a respective plurality of feature channels comprises the set of features.

There are provided methods, systems and non-transitory storage mediums for predicting growth of an abdominal aortic aneurysm (AAA) of a patient having been diagnosed with AAA. Segmented regions of interest (ROI) comprising the aorta and adjacent structures are received by segmenting a set of images. A wall shear stress parameter and intraluminal thickness parameter is determined. A 3D parametric mesh comprising a plurality of concentric 3D mesh layers is generated, where each concentric 3D mesh layer includes a same predetermined number of nodes. The generation includes encoding the segmented ROIs, the wall shear stress parameter and the intraluminal thickness parameter as features at respective node locations in the 3D parametric mesh. A trained growth prediction machine learning model predicts, based at least on a subset of features of the 3D parametric mesh, if the given patient will show AAA growth. The training of the growth prediction model is also disclosed.

A method of identifying coronary artery disease comprising: receiving contrast cardiac CT data indicative of a contrast cardiac CT scan carried out on a patient; analysing the contrast cardiac CT data using a vessel seed detector and machine learning to identify a plurality of centreline seed points in the contrast cardiac CT data predicted to correspond to locations on centrelines of the cardiac arteries of the patient; determining whether the analysis to identify centreline seed points of patient coronary arteries is incorrect or incomplete; if the analysis to identify centreline seed points of patient coronary arteries is incorrect or incomplete, reconfiguring the vessel seed detector; producing data indicative of transverse image slices of the cardiac arteries of the patient using the contrast cardiac CT data and the centreline seed points identified using the reconfigured vessel seed detector;and identifying presence of coronary artery disease using the transverse image slices.

A method of automatically determining a plaque score for coronary arteries of a patient is disclosed. The method involves receiving cardiac CT data indicative of a cardiac CT scan carried out on the patient, and analysing the cardiac CT data to identify plaque volumes to be included in the plaque score, the plaque volumes located on the coronary arteries. The method also includes determining locations of the identified plaque volumes on the coronary arteries, applying machine learning to the cardiac CT data to identify a plurality of primary key points on the coronary arteries, determining a distance between each identified plaque volume and an associated primary key point, and determining a plaque score based on a heart dimension value and, for each identified plaque volume, the determined distance from the identified plaque volume to the associated primary key point.

An image processing apparatus is disclosed. The image processing apparatus of the present invention comprises: an image receiving unit for receiving a first image and a second image of the same object taken at different times; a processor for obtaining transformation information by registering the first image on the basis of the second image, obtaining a first segment image corresponding to an area of the object from the first image, and generating a second segment image corresponding to an area of the object of the second image by transforming the obtained first segment image according to the transformation information; and an output unit for outputting the second segment image.

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

A computer implemented method for training a whole medical image foundation model, including: receiving a plurality of medical image datasets; extracting local sections of image data from the plurality of medical image datasets; obtaining one or more causal variables associated with the local sections and / or patient; training one or more self-supervised learning models based on the local sections of image data and the causal variables; combining the one or more trained self-supervised learning models with a deep learning network configured to combine a latent representation of the local sections of image data from the one or more trained self-supervised learning models into a patient-level representation; and combining, with the one or more trained self-supervised learning models and the deep learning network, at least one further network or function configured to accept the patient-level representation as input, the at least one further network or function operable to perform one or more patient-specific prediction tasks.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and / or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and / or dynamically identify one or more features, such as plaque and vessels, and / or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and / or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and / or quantified parameters.

A method of automatically determining a plaque score for coronary arteries of a patient is disclosed. The method involves receiving cardiac CT data indicative of a cardiac CT scan carried out on the patient, and analysing the cardiac CT data to identify plaque volumes to be included in the plaque score, the plaque volumes located on the coronary arteries. The method also includes determining locations of the identified plaque volumes on the coronary arteries, applying machine learning to the cardiac CT data to identify a plurality of primary key points on the coronary arteries, determining a distance between each identified plaque volume and an associated primary key point, and determining a plaque score based on a heart dimension value and, for each identified plaque volume, the determined distance from the identified plaque volume to the associated primary key point.

The invention relates to the technical field of medical image processing, and discloses a craniofacial dynamic reconstruction method and system based on multi-modal data fusion, and the method comprises the steps: arranging a multi-modal data collection device in a target craniofacial region, and obtaining a static CT image, a static MRI image, a dynamic expression video sequence and a surface electromyogram signal; preprocessing the static CT image, the static MRI image, the dynamic expression video sequence and the surface electromyogram signal; inputting the preprocessed data into a multi-scale finite element model, and simulating a coupling relationship between muscle contraction force and skin deformation by adopting a biomechanical driving strategy to generate a dynamic craniofacial model; and fusing the geometric error and the motion consistency score of the real data by adopting a linear regression method, and outputting a comprehensive reconstruction quality index. According to the method, the problems of low craniofacial dynamic modeling accuracy and poor robustness in the prior art can be solved.

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

The invention provides a real-time three-dimensional imaging system in a thoracic surgery, and relates to the field of thoracic surgery auxiliary equipment, and the system comprises a multi-modal image collection module which is used for collecting multi-source data of tissues and organs in a thoracic cavity; the data core processor is used for processing and fusing the multi-source data collected by the multi-mode image acquisition module; the three-dimensional reconstruction module is used for generating a dynamically updated submillimeter-level precision three-dimensional model according to the processed and fused multi-source data and marking a dangerous structure and a safety boundary; and the augmented reality navigation module is used for superposing the three-dimensional model on an operation visual field through a holographic head-mounted display, and realizing real-time three-dimensional visual navigation in combination with instrument tracking and a multi-stage early warning mechanism. According to the invention, radiation-free and high-precision real-time three-dimensional visual navigation can be provided, and the precision and safety in the thoracic surgery can be ensured.

A computer-implemented method for medical measurement reconstruction may comprise obtaining a first reconstruction of at least one representation of at least one set of medical measurements; presenting the first reconstruction or information about the first reconstruction to a reviewer; receiving an input from the reviewer relating to the first reconstruction or the information about the first reconstruction; processing the received input; and generating a second, modified reconstruction based on the received input.