24 results about "Paranasal sinuses" patented technology

The invention discloses a chronic sinusitis CT (Computed Tomography) image automatic typing and severity assessment method and a chronic sinusitis CT image automatic typing and severity assessment system based on deep learning. The method comprises the following steps: acquiring paranasal sinus CT image data of a chronic sinusitis patient and an associated clinical tag; carrying out standardization processing on the CT image, wherein the standardization processing comprises gray level normalization, denoising and region-of-interest segmentation; a multi-task deep learning model is constructed, an improved 3D Re < s> Ne < t-50 > architecture is adopted by a typing sub-model to output an immune endotype classification result, and a severity evaluation sub-model segments a lesion area based on a U-Ne < t + + > structure and automatically calculates a severity level; integrating model output to generate individualized treatment suggestions; and superposing a labeling result through the thermodynamic diagram and embedding the labeling result into a hospital PACS system. Accurate typing and evaluation of chronic nasosinusitis are achieved, and diagnosis efficiency and clinical decision support capability are improved.

Compositions for use in preventing or treating an infection of the nasal passages, sinuses, or both of a subject are described. The compositions include one or more peptoid compounds in an amount effective to prevent or treat the infection in the nasal passages, sinuses, or both. The compositions include the one or more peptoid compounds in an amount effective to inhibit one or more pathogenic bacteria, pathogenic fungus, or pathogenic virus in the nasal passages, sinuses, or both, while having relatively little or no activity against commensal bacterial species, commensal fungal species, commensal viral species, or any combination thereof, in the nasal passages, sinuses, or both of the subject.

The present invention relates to a patch (1) for the topical treatment of sinusitis in a person to be treated, the patch (1) comprising at least one active section (2) with at least one active ingredient and at least one adhesive section (3), wherein the patch (1) is designed to be at least partially, preferably completely, occlusive in the at least one active section (2) and / or in the at least one adhesive section (3), wherein it is provided according to the invention that the at least one active section (2) contains a therapeutically effective amount of a non-steroidal anti-inflammatory drug and / or its physiologically compatible compounds / salts and / or physiologically compatible chemical derivatives as the at least one active ingredient, and that the patch (1) has a shape that is adapted to the anatomical conditions of the application site, wherein the application site is in the face in the area of ​​at least one of the paranasal sinuses,preferably located in the area of ​​the cheek of the person to be treated, in order to enable targeted percutaneous treatment of the sinusitis.

A balloon dilation catheter includes a substantially rigid inner guide member and a movable shaft coupled to a balloon that is slidably mounted on the substantially rigid inner guide member. To treat a sinus cavity of a subject using the balloon dilation the substantially rigid inner guide member is advanced into a drainage pathway of the sinus (e.g., frontal recess or maxillary sinus) of the subject via a nasal passageway. The shaft and balloon are advanced in a distal direction over the substantially rigid inner guide member to place the balloon in the drainage pathway. The balloon is inflated to expand or otherwise remodel the drainage pathway.

The application relates to the technical field of medical devices, and particularly provides a paranasal sinus teaching device which comprises a main body mounting seat, an anatomical mounting piece and a guiding piece, the main body mounting seat comprises a model of a single-side nasal cavity and paranasal sinus, a plurality of containing cavities are arranged in the model, the anatomical mounting piece is detachably mounted on the containing cavities, a plurality of anatomical mounting pieces are arranged in each containing cavity, the plurality of anatomical mounting pieces are used for being selectively mounted in the corresponding containing cavities to form a pathological model combination in different disease states. The problem that a plurality of paranasal sinus models need to be purchased for learning the normal state and various disease states of the paranasal sinus is solved.

The utility model relates to the technical field of medical instruments, in particular to a medicine spraying device used after paranasal sinus surgery, which comprises a medicine spraying bottle body, a medicine outlet pipe is communicated with the medicine spraying bottle body, a bottle cap is arranged on the medicine spraying bottle body, the medicine spraying device further comprises a replacement mechanism, the replacement mechanism is arranged on the medicine outlet pipe, the replacement mechanism comprises a butt joint pipe, a butt joint groove and two fixing frames, and the butt joint pipe is communicated with the butt joint groove. A butt joint pipe is fixedly connected to a medicine outlet pipe, through cooperation of a spring, a fixing frame, a lifting plate, a clamping block and the like, the fixing block can be conveniently limited and fixed, a butt joint groove can be conveniently fixed to the medicine outlet pipe, medical staff can conveniently use disposable sprayers of different specifications according to the illness states of patients and different patients, and rapid postoperative recovery of the patients is facilitated; and through cooperation of a butt joint groove, a disposable spray head and the like, it is avoided that the spray head is cleaned after a patient uses the device, and safety and practicability are improved.

The invention discloses a chronic sinusitis full-automatic segmentation method based on deep learning and related equipment. The method comprises the following steps: acquiring paranasal sinus CT image data of a chronic sinusitis patient, wherein the paranasal sinus CT image data comprises paranasal sinus CT image data of patients with different genders, ages and disease course stages; dividing the paranasal sinus CT image data into a training verification set and a test set, and training an nnUNetV2 model based on the training verification set to obtain a chronic sinusitis region-of-interest segmentation model; and performing full-automatic segmentation of chronic sinusitis on CT image data of a target patient through the segmentation model of the region-of-interest of chronic sinusitis. The problems of low segmentation efficiency, high subjectivity and difficulty in precise segmentation of the chronic sinusitis region-of-interest caused by high complexity and individual variability of the anatomical structure of the nasal cavity and the paranasal sinus can be solved.

The invention discloses an endoscope-holding manipulator based on a Krasserian origami module for paranasal sinus surgery, and belongs to the technical field of minimally invasive surgery robots. The lens-holding manipulator comprises a fixed platform base, a movable platform operating end and at least three branched chain groups for connecting the fixed platform base and the movable platform operating end, each group of branch chains is formed by connecting a plurality of Kreishin origami modules in series; each Kreishin paper folding module comprises three branch chains; the length of a branch chain of the Kreishin paper folding module can be independently controlled; the remote motion center restraining function of the endoscope is achieved through the foldable characteristic of the Krasserian origami module and the kinematics advantages of the parallel origami units. By utilizing the foldability of a paper folding structure and the geometrical characteristics of a parallel mechanism, the parallel mechanism has the advantages of high precision of a remote motion center, compact structure, modularization and expandability, reduces the risk of damage of instruments to fragile tissues in a paranasal sinus endoscopic surgery, improves the operation flexibility, and is suitable for popularization and application in the field of paranasal sinus endoscopic surgery. And the pose adjustment and positioning of the endoscope are realized through the folding / unfolding of the Krislingorigami module and the length change of the branch chains.

The application discloses a kind of based on multilevel prompt learning paranasal sinus image automatic identification and segmentation method, it is related to the technical field of computer vision and biological information engineering.The method comprises the following steps: obtaining the multilevel visual features of paranasal sinus;Based on multilevel prompt learning, a multi-view prompt learning model is constructed, and the context prompt, mixed multi-modal prompt and label prompt of the original paranasal sinus image are obtained using the multi-view prompt learning model to obtain the multi-view prompt of paranasal sinus;A paranasal sinus segmentation network is constructed, and the multilevel visual features of paranasal sinus and the multi-view prompt of paranasal sinus are used to obtain the paranasal sinus image automatic identification and segmentation result.The application can solve the problem of lacking medical prior knowledge and sufficient semantics, avoid the continuous adjustment of semantic space during optimization, and reduce the interference of task-independent cross-modal concepts, thereby improving the accuracy of paranasal sinus image automatic identification and segmentation result.

The invention discloses a lipoic acid-dopamine synergistically toughened fibroin composite coating applicable to a paranasal sinus stent, and a preparation method and application thereof, and belongs to the field of surface modification of biomedical materials. The preparation method comprises the following steps: firstly, dissolving lipoic acid and dopamine in a Tris-HCl solution to prepare a lipoic acid-dopamine mixed solution; dissolving water-soluble silk fibroin in ultrapure water to prepare a silk fibroin aqueous solution; and finally, mixing the two solutions to prepare a composite coating preparation solution, coating the surface of a to-be-coated structure with the composite coating preparation solution, and drying to form the composite coating. The composite coating is applied to the paranasal sinus stent, and the paranasal sinus stent with the composite coating on the surface is obtained. The silk fibroin-polylipoic acid-polydopamine ternary synergistic cross-linking system constructed by the invention can realize long-term stability of a flexible polymer network; the preparation method is low in cost and easy and convenient to operate, and the composite coating is compact, uniform and excellent in flexibility and can cooperate with the stent to achieve expansion deformation. The coating has the capabilities of promoting healing by photothermal, efficiently resisting oxidation and inhibiting fibroblast proliferation; the material has a corrosion protection function, and provides a new path for surface modification of paranasal sinus stent materials.

The invention generally relates to systems and methods for targeting of specific tissue(s) of interest within a sino-nasal region of a patient, specifically sinus regions (i.e., ostia and sinus cavities), for the treatment of chronic sinusitis conditions.

The invention discloses a continuous flushing system for fungal nasosinusitis, and belongs to the technical field of medical auxiliary instruments, the continuous flushing system comprises a peristaltic pump, a pump head is arranged below the front surface of the peristaltic pump, a flushing assembly is arranged on one side of the pump head, and the flushing assembly comprises a flushing pipeline arranged in the pump head; a flushing head assembly is arranged at one end of the flushing pipeline and comprises a first bent pipe section, a second bent pipe section and a third bent pipe section, the first bent pipe section is fixedly installed at one end of the flushing pipeline, the second bent pipe section is arranged on the inner wall of the first bent pipe section, and the third bent pipe section is arranged on the inner wall of the second bent pipe section. The multiple bent pipe sections are connected in a sleeved mode and can stretch out and draw back, all walls of the maxillary sinus can be flushed by means of the flushing heads at different angles, and continuous or pulse type water flow can form vortexes in the maxillary sinus to roll away fungi high in sticky adhesive force without damaging the paranasal sinus mucosa.

The invention belongs to the technical field of medical instruments, and particularly relates to an auxiliary device suitable for paranasal sinus negative pressure replacement and a using method.The auxiliary device comprises two clamping handles and a controller, an elastic bent strip is arranged between the two clamping handles, and the two ends of the elastic bent strip are fixedly connected with the inner walls of the two clamping handles correspondingly; the inner side wall of the tail end of the clamping handle is fixedly connected with a first induction piece, the tail end of the clamping handle is fixedly connected with an expansion air bag, and the clamping handle is of a cavity structure. An air pump is further included, the output end of the air pump is fixedly communicated with a catheter, the outer end of the catheter is fixedly communicated with a three-way pipe, and the other two ends of the three-way pipe are communicated with the two clamping handle cavities respectively. Compared with a traditional method, the requirement for the body position of a patient is not very strict, the matching degree of the patient is greatly increased, the possibility that medicine flows into the throat and the lower respiratory tract is limited through the expansion air bag of the rear nostril, the reaction degree of nausea and vomiting of the patient is greatly reduced, and complications are also reduced.

The invention provides a paranasal sinus bone structure medical image segmentation system based on Mamb-UNet, and relates to the technical field of medical image processing.The paranasal sinus bone structure medical image segmentation system comprises the steps that firstly, a low-resolution global abstract graph is extracted, original features are injected, and a local extractor is endowed with context sensing capacity; and the bone slices with similar forms and different meanings can be distinguished according to anatomical positions, so that false alarms are remarkably reduced. The invention aims to ensure that the boundary of the segmented bone structure is clear by introducing a gating type bidirectional fusion mechanism and dynamically arbitrating the weights of forward and backward information streams by utilizing a learnable gating unit. According to the method, a hierarchical parallel Mama (H-Mama) architecture is designed, and parallel multi-scale feature extraction of features is realized in the same feature level. By operating high-frequency, intermediate-frequency and low-frequency branches in parallel, the model can capture fine bone wall details and macroanatomical layout simultaneously without compromise so as to adapt to violent size changes.

Described herein are methods and devices for delivering a drug to the frontal sinus system. An inflatable implant is positioned within the frontal sinus system using an anchoring means secured within the frontal sinus cavity. A drug-containing fluid is released directly into the frontal sinus drainage system.

The invention provides a temporary paranasal sinus opening instrument, and belongs to the technical field of medical instruments. Comprising a conveying catheter and a supporting stent, the supporting stent comprises a tubular supporting part and a recycling part located at one end of the supporting part, the supporting part comprises a tubular framework and a hemostasis component arranged on the outer side of the tubular framework in a covering mode, and the tubular framework is an alloy stent with a shape memory function; the recovery part comprises a channel opening formed in one end of the tubular framework and a connecting rod, the channel opening is a beveled opening with the opening face forming an acute angle with the axis of the supporting part, the connecting rod is connected with the end, farthest from the other end of the tubular framework, of the channel opening, and the supporting part has the contraction state that the supporting part is folded and stored in the conveying catheter. The stretching state extends out of the conveying catheter and is released to be opened. The technical problem that in an existing paranasal sinus operation, the operation efficiency is low due to instrument defects can be solved.

The invention discloses a chronic sinusitis prognosis prediction method based on deep learning and related equipment. The method comprises the following steps: acquiring paranasal sinus CT image data and prognosis result data of a chronic sinusitis patient; performing model training on the deep learning models of at least two model structures on a training set formed by the paranasal sinus CT image data and the prognosis result data; and selecting a model with optimal performance from the trained deep learning models as a target deep learning model, determining a chronic sinusitis prognosis prediction model based on the target deep learning model, and performing chronic sinusitis prognosis prediction. The problems that traditional CT scoring depends on subjective judgment of doctors, the scale of a scoring system is narrow, pathological features and severity of inflammation cannot be reflected, the influence of subjective factors of evaluators is large, the correlation with disease prognosis is weak, and the requirement of CRS precise diagnosis and treatment is difficult to meet can be solved.

Systems and methods for deploying a stent within the frontal sinus. The stent includes flexible foam and film layers arranged in a stacked configuration and furled within a cartridge prior to deployment. The cartridge is removably coupled to an applicator device including an actuator. The film layer may include a polymer having a resilience sufficient to unfurl the stent and maintain patency of the frontal sinus opening. The flexible foam layer may have porosity of greater than 80%, and an active agent may be within the flexible foam layer. The flexible foam layer may be bioresorbable and the flexible film layer biocompatible and non-biodegradable. The stent may include first and second body portions with the first body portion independently unfurling from the second body portion to retain the stent within the frontal sinus. Contouring of the first and second body portions may facilitate ease with removal of the stent.

A method of using a sinus treatment device includes holding a treatment electrode against facial skin at a treatment location associated with reduction of sinus discomfort and / or congestion. The sinus treatment device may automatically detect a treatment location. In another embodiment, the sinus treatment device may be triggered by the user.

The invention discloses a paranasal sinus and Eustachian tube therapeutic apparatus with adjustable carrier gas pressure variation amplitude and frequency and a method, and belongs to the technical field of medical apparatus and instruments. The device comprises a magnetic shielding sleeve, a rotating cylinder and an air chamber, the rotating cylinder is rotatably mounted between the magnetic shielding sleeve and the air chamber; an air bag is mounted in the air chamber; an air chamber hole is formed in the side wall of the air chamber, and an inner-layer magnet is mounted in the air chamber hole; the inner-layer magnet is connected with the pressing piece through the connecting rod, and the pressing piece abuts against the air bag. A rotating hole corresponding to the air chamber hole is formed in the rotating cylinder, and an outer-layer magnet is mounted in the rotating hole; and the gas chamber is connected with the gas carrying pipeline through the elastic membrane. According to the invention, after the carrier gas carrying the medicine reaches the cavity of the paranasal sinus or the eustachian tube, the inner wall of the paranasal sinus or the eustachian tube is obviously changed in form under the action of pulse air pressure, so that the medicine coverage is effectively improved, and the treatment effect of the atomization therapeutic apparatus is improved.

The invention relates to a paranasal sinus or auditory meatus intelligent cleaning method and device. The method comprises the steps that initial cleaning pressure parameters are obtained according to personalized physiological parameters of a user, and a target cavity entrance is positioned through stereo image data; driving a servo motor to adjust the attitude of the nozzle according to the image data and the calculated nozzle target pointing angle and feeding back angle information in real time; flushing fluid is output according to the initial pressure parameters, and real-time pressure feedback data are collected by a pressure sensor; the physiological parameters, the angle data and the pressure data are input into a cleaning decision model, a real-time optimized cleaning instruction is generated, and the flushing pressure is dynamically adjusted through a control module; after cleaning is completed, flushing is automatically stopped, and the negative pressure suction module is started to adsorb residual liquid in the cavity; the humidity sensor continuously monitors the humidity, and once the humidity is lower than a preset drying threshold value, suction work is stopped. According to the invention, the cleaning process always adapts to the current state of the user, and the safety and comfort are obviously improved.

An implant for a sinus cavity that can have a main body portion and a second body portion coupled with the main body portion. In some embodiments, the second body portion can extend at an angle away from the main body portion. The implant can be sized and configured for implantation in the frontal sinus. A size and a shape of the implant can be similar to a size and a shape of the frontal sinus of a patient that the implant will be implanted into.WO

The utility model aims to provide a negative pressure recovery type paranasal sinus flushing and sucking device which comprises a shell and a flushing and sucking assembly, a clean liquid chamber and a waste liquid chamber which are mutually independent are arranged in the shell, a spray head and a flushing pipe are arranged at the top of the shell, one end of the flushing pipe extends into the spray head, and a recovery groove is formed between the outer side wall of the flushing pipe and the inner side wall of the spray head. The recovery tank is communicated with the waste liquid chamber, the clean liquid chamber is communicated with the spray head through the flushing pipe, the flushing and sucking assembly comprises an atomizing part, an air pump and a button, the atomizing part is arranged in the clean liquid chamber, the air outlet end of the atomizing part extends into the flushing pipe and is communicated with the flushing pipe, and a suction hole and an air leakage hole are further formed in the shell. The suction hole is communicated with the negative pressure end of the air pump and the waste liquid chamber, the air leakage hole and the air inlet end of the atomization piece are both communicated with the positive pressure end of the air pump, and the button is arranged on the outer side wall of the shell in a sliding mode and used for blocking the air leakage hole when stressed.

The invention provides a device for collecting a nasal secretion sample. The device includes a sample collection member comprising a material for collecting a predetermined volume of a nasal secretion sample. The device further includes a handle and an elongated support member extending between the handle and the sample collection member and for supporting the sample collection member. The device is adapted for a user holding the handle to locate the sample collection member in contact with tissue at a target location inside the nasal cavity where the sample collection member collects a predetermined volume of a nasal secretion sample.