87 results about "Anaerobic bacteria" patented technology

The invention provides a modified iron-based biochar composite material, a preparation method and application of the modified iron-based biochar composite material in rapid recovery of seriously acidified kitchen waste anaerobic engineering. The preparation method comprises the steps of low-temperature carbonization treatment, activation treatment, coprecipitation method modification, surface coating of a conductive polymer and the like. In the process of preparing the modified iron-based biochar composite material, the biochar has a higher specific surface area and a porous structure through activation treatment, the adsorption capacity of the biochar is improved, more iron elements can be doped, electron transfer is promoted, and the electron transfer process between acid-producing bacteria and methanogens is enhanced; besides, the surface of the iron-based biochar is coated with a conductive polymer, so that the overall conductivity and electron transfer efficiency of the material can be obviously improved, an electron transfer network between acid-producing bacteria and methanogens is perfected, and the anaerobic digestion efficiency is greatly improved, thereby quickly recovering a seriously acidified kitchen waste anaerobic system.

The invention relates to an Alzheimer's disease marker based on intestinal flora and a risk prediction model. The Alzheimer's disease marker based on the intestinal flora comprises the intestinal flora, wherein the intestinal flora comprises anaerobic lawsonia pasteurianus, escherichia coli, streptococcus salivarius, assa wig, clostridium luviergii, intestinal rosebawii, rosella faecalis, human rosella, trichothecium CAG424 and clostridium CAG58. The invention further discloses a preparation method of the alzheimer's disease marker based on the intestinal flora, and the alzheimer's disease marker based on the intestinal flora comprises the intestinal flora and an application of the alzheimer's disease marker based on the intestinal flora. The Alzheimer's disease marker based on the intestinal flora is excavated, the Alzheimer's disease risk prediction model based on the intestinal flora is further constructed, and the method has the advantages of being high in detection accuracy, convenient, rapid, safe and noninvasive and has important clinical guiding significance in auxiliary diagnosis of Alzheimer's disease related indexes.

This utility model relates to a wastewater treatment device for chloroamine production, belonging to the field of wastewater treatment technology. It includes a treatment tower with a dividing funnel in the upper middle part that separates it into an upper aerobic zone and a lower anoxic zone. The upper aerobic zone contains multiple fluidized bed packings, and an effluent weir is located at the top of the upper aerobic zone. An overflow pipe is located on the outer side of the bottom of the effluent weir on the treatment tower, connecting to the lower anoxic zone. The lower anoxic zone consists of a biological packing layer, a filter layer, and a filter plate from top to bottom. An effluent pipe is located at the bottom of the treatment tower. This utility model integrates the upper aerobic zone and the lower anoxic zone vertically within the treatment tower, significantly saving floor space. After entering the treatment tower, the wastewater first undergoes nitrification in the upper aerobic zone under aeration, and then overflows through the effluent weir into the lower anoxic zone, where denitrification occurs due to the anaerobic bacteria on the biological packing layer. This ensures more thorough contact between microorganisms and water, resulting in higher wastewater treatment efficiency.

The presently disclosed subject matter provides methods and kits for treating solid tumors in a subject by using a combination of anti-CTLA-4 and / or anti-PD-1 antibodies with at least one member of the group consisting of a bacterium, bacterial product, and an immunoregulatory entity. In particular embodiments, the bacteria are toxin-depleted, anaerobic bacteria, such as Clostridium novyi-NT.

The invention relates to a microbial single-cell gelation encapsulation method based on aloe gel and application, the method realizes single-cell gelation encapsulation through electrostatic interaction of sterile aloe gel and intestinal anaerobic bacteria (such as Agathobacter rectasis), and the method comprises the specific steps of aloe gel preparation, bacterial suspension culture and oscillation mixing to form a stable structure. The preparation method has the advantages that the acid resistance and biocompatibility of the natural aloe gel are utilized to replace a traditional synthetic material, so that the gastrointestinal tolerance of thalli is improved; meanwhile, the synergistic effect of aloe active ingredients (such as aloe-emodin) and intestinal bacterial metabolites (butyric acid) is combined, so that the anti-inflammatory and intestinal steady-state regulation and control effects are enhanced. Experiments show that the survival rate of the encapsulated bacteria in simulated gastric juice within 4 hours is larger than or equal to 90%, the intestinal colonization rate is effectively increased compared with naked bacteria, the inflammatory factor level of a colitis model mouse can be remarkably reduced, and a safe and efficient new strategy is provided for micro-ecological treatment of inflammatory bowel diseases.

Provided herein are compositions comprising one or more substantially pure strains of bacteria as well as methods of making and using the same to treat and / or prevent one or more lipid and / or insulin related disorders and to regulate or alter the metabolism of lipids and / or insulin in a subject in need thereof.

The utility model relates to a sandwich China-hemp cushion core and a mattress, belongs to the field of bedding articles, and provides the sandwich China-hemp cushion core aiming at the problem that an existing cushion core cannot give consideration to environmental protection and structural integrity, the sandwich China-hemp cushion core comprises two hot melting cotton layers and a China-hemp layer, the two hot melting cotton layers are connected with the upper surface and the lower surface of the China-hemp layer respectively, and the two hot melting cotton layers are connected with the upper surface and the lower surface of the China-hemp layer respectively. Therefore, the sandwich China-hemp cushion core forms a whole. The China-hemp layer is made of China-hemp fibers and is of a hollow structure, a cavity is filled with oxygen, anaerobic bacteria cannot survive, meanwhile, the moisture guiding and ventilating effects are good, the China-hemp layer is clamped between the two hot melting cotton layers, the China-hemp layer is kept in a good shape, the hot melting cotton layers are good in flexibility and not prone to breakage, the China-hemp layer is well protected, and the service life of the China-hemp layer is prolonged. And the hemp layer is effectively prevented from being crushed and damaged, so that the sandwich hemp cushion core disclosed by the utility model can give consideration to both environmental protection performance and structural integrity.

The utility model belongs to the technical field of anaerobic bacteria culture, and is particularly a sealing device for anaerobic bacteria culture, comprising a box body, a humidity sensor is provided through the top of the box body, a humidifier is provided on the top of the box body, a connecting pipe is provided at the output end of the humidifier, a connecting port is provided through the middle part of the top of the box body, a diffusion rack is provided through the transmission pipe, and a spray port is provided in the bottom array of the diffusion rack. The utility model is installed with a diffusion rack and a spray port. When the sealing device for anaerobic bacteria culture is used, the humidifier is operated through the connection between the connecting pipe and the connecting port, which will form a transmission effect on moisture. After entering the transmission pipe, the moisture will evenly enter the diffusion rack, and then be evenly discharged through the spray port, forming an effect of controlling and regulating the humidity in the box body, solving the technical problem that the humidity control of the anaerobic culture box is usually not accurate enough, resulting in unsatisfactory culture conditions and affecting the culture results.

The present invention provides an organic fertilizer production and processing equipment, including a reaction container and a deoxygenation device, wherein the reaction container is configured to contain organic raw materials for dry anaerobic fermentation reaction; the deoxygenation device is arranged in the reaction container and configured to consume or filter the oxygen in the reaction container. In the organic fertilizer production and processing equipment of the present invention, the deoxygenation device consumes or filters the oxygen in the reaction container to maintain an oxygen-free atmosphere in the reaction container. Even if the seal fails and the outside air enters the reaction space, the fermentation environment of the anaerobic bacteria can be prevented from being destroyed, the mixing of oxygen and biogas in the reaction space can be prevented, and the reaction temperature can be prevented from rising, thereby facilitating the fermentation reaction of anaerobic microorganisms, solving the problem of air easily entering the reaction container, and achieving the purpose of improving the quality of organic fertilizer.

The present invention provides a method for increasing the growth efficiency in an anaerobic microbial fermentation of a microorganism capable of converting CO2, CO or a mixture thereof into at least one organic compound, the method comprising growing the microorganisms in a cultivation medium comprising selenium in a concentration which is at least 1.2 μM.

A gas concentration regulator for anaerobic bacteria culture, comprising: (a) dehydroascorbic acid; (c) a transition metal catalyst; (d) activated carbon; (e) at least one selected from the group consisting of alkali metal carbonates, alkali metal hydroxides, and alkaline earth metal hydroxides; and (f) water.

Cyclic dinucleotides (CDRs) are signaling molecules for cancer therapy, acting as second messengers for intracellular events initiated by GPCR activation and stimulating factors for the interferon gene (STING), thus significantly influencing tumor suppression. Simultaneously, when cancer occurs in a subject, angiogenesis and cell growth proceed at very high rates in vivo, creating a hypoxic environment due to incomplete angiogenesis in cancerous tissue. This environment can be highly conducive to the proliferation of anaerobic bacteria such as Salmonella strains or Escherichia coli. Therefore, this invention relates to a DNA construct incorporating a gene encoding an enzyme for synthesizing cancer therapeutic signaling molecules (e.g., CDRs), or to strains transformed with a vector containing the DNA construct. According to the invention, the DNA construct or strains transformed with a vector containing the DNA construct target cancer in a subject and then secrete C-di-AMP or C-di-GMP synthases in the surrounding environment of the cancer, thus enabling highly effective prevention or treatment of cancer while allowing for real-time cancer diagnosis.

Agents, kits, and methods that utilize oxygenation to treat Inflammatory Bowel Disease (IBD) and / or provide prophylaxis against exacerbation of IBD are provided. In several embodiments, the agents, kits, and methods according to several embodiments generate in, or carry to, oxygen in the intestinal lumen to treat IBD and provide prophylaxis against exacerbation of IBD, including those caused by the presence of anaerobic bacteria in the intestine. The agents, kits, and methods provided herein generate an aerobic environment within the intestine to alleviate intestinal inflammation.

An artificial airway capable of preventing secretion retention on a cuff comprises a catheter body, a suction tube, an oxygen supply tube, an indicating tube, an indicating balloon and an inflation cuff, the indicating tube is connected with the indicating balloon and the inflation cuff, the inflation cuff is arranged on the outer side of the catheter body in a sleeving mode, the suction tube, the oxygen supply tube and the indicating tube are fixedly installed on the catheter body, and the oxygen supply tube is connected with the inflation cuff. Wherein the ends, close to the exhalation machine, of the catheter body and the inflation cuff are near ends, the ends, away from the suction machine, of the catheter body and the inflation cuff are far ends, the inflation cuff is installed at the position, close to the far end, of the catheter body, the catheter body is provided with a first channel, a second channel, a third channel and a fourth channel, and the second channel is used for installing an indicating tube. The suction tube is arranged in the third channel in a penetrating mode and extends out of the third channel, the oxygen supply tube is arranged in the fourth channel in a penetrating mode, the fourth channel is provided with an inlet and an outlet, and the outlet of the fourth channel is formed in the position close to the near end of the inflation cuff; the sputum pool can prevent secretions in the throat and the oral cavity from flowing into the sputum pool above the inflatable cuff, eliminates the local anaerobic environment of the sputum pool, is not beneficial to the growth of anaerobic bacteria, effectively prevents pathogenic bacteria and colonization bacteria from growing and breeding in the sputum pool, and improves the sputum pool quality. Therefore, the sputum pool above the inflatable cuff does not have retention secretions with pathogenic bacteria which can cause sputum pool mucosa infection or leakage into the lower respiratory tract to cause repeated pneumonia.

The constant-temperature incubator comprises an incubator body, a heating mechanism is arranged in the incubator body, an incubator door is rotatably arranged on the incubator body, a plurality of pairs of mounting blocks are arranged in the incubator body, and first sliding grooves are formed in the mounting blocks; a placement assembly is detachably arranged in the box body and comprises a placement plate, second sliding grooves are symmetrically formed in the bottom of the placement plate, threaded rods are rotatably arranged in the second sliding grooves, the thread directions of the two ends of the threaded rods are opposite, the two ends of the threaded rods are in threaded connection with first moving blocks, and the first moving blocks are slidably arranged in the second sliding grooves; a scissor-fork lifting frame is arranged on the first moving block, second moving blocks are connected to the two ends of the bottom of the scissor-fork lifting frame, and the second moving blocks are in sliding connection with the first sliding grooves; one end of the threaded rod extends out of the placing plate and is connected with a rotating handle. The distance between the adjacent placing plates is adjusted through the shear type lifting frame, so that the placing plates with different heights are suitable for placing culture tanks with different sizes, the adjustment is convenient, and the use is flexible.

Agents, kits, and methods that utilize oxygenation to treat Inflammatory Bowel Disease (IBD) and / or provide prophylaxis against exacerbation of IBD are provided. In several embodiments, the agents, kits, and methods according to several embodiments generate in, or carry to, oxygen in the intestinal lumen to treat IBD and provide prophylaxis against exacerbation of IBD, including those caused by the presence of anaerobic bacteria in the intestine. The agents, kits, and methods provided herein generate an aerobic environment within the intestine to alleviate intestinal inflammation.

This invention relates to a method and system for treating pulping wastewater. The method includes: mixing pulping wastewater and papermaking wastewater for coagulation treatment to obtain coagulated water; the coagulated water entering a primary sedimentation tank for primary sedimentation treatment to obtain primary sedimentation water; the primary sedimentation water entering an equalization tank, where it is mixed with effluent from the secondary sedimentation tank of a papermaking wastewater treatment system for equalization treatment to obtain equalized water; the equalized water entering a pre-acidification tank, where it is mixed with effluent from the secondary sedimentation tank of a papermaking wastewater treatment system for pre-acidification treatment to obtain pre-acidified water; and the pre-acidified water entering an anaerobic reactor for anaerobic purification treatment to obtain treated water. The treatment method provided by this invention can reduce the harm of pollutants such as H2O2 and lignin in pulping wastewater to anaerobic bacteria, improve the anaerobic treatment effect, and reduce the COD content of the treated water, thus having application prospects and industrial value.

The present application relates to the technical field of medical devices, and discloses a wound treatment patch for a high flow rate humidification therapeutic instrument, which comprises a gas-permeable transparent film, an adhesive layer, a connection base and a connecting member, and a plurality of air holes are formed in the gas-permeable transparent film; the adhesive layer is arranged along the peripheral edge of the gas-permeable transparent film; the connection base is installed on one side wall of the adhesive layer and has a hollow channel; one end of the connecting member is connected with the connection base, and the other end of the connecting member is used for being connected with the interface of the high flow rate humidification therapeutic instrument. In this way, the gas chamber formed by the gas-permeable transparent film, the adhesive layer and the skin wound can accommodate gas, the plurality of air holes on the gas-permeable transparent film can be used for discharging gas outward, so that the high flow rate humidification gas entering through the connection base can be filled in the gas chamber, the growth of anaerobic bacteria is inhibited, and the skin wound healing is accelerated.

The utility model relates to the technical field of biological experiment equipment, in particular to a mouse gavage device with an anaerobic bacteria fermentation concentration monitoring function, which comprises a biological fermentation tank and further comprises a first draw-off pump, a second draw-off pump, a third draw-off pump, a fourth draw-off pump and a fourth draw-off pump, the analysis device is communicated with the first draw-off pump and is used for analyzing the concentration of the fermentation product; the second draw-off pump is communicated with the biological fermentation tank and is used for extracting a fermentation product in the biological fermentation tank for intragastric administration; one end of the stomach tube is communicated with the second draw-off pump, and a gavage needle is arranged at the other end of the stomach tube and used for injecting the fermentation product into the stomach of the mouse; the first draw-off pump, the analysis device, the second draw-off pump and the stomach tube are hermetically connected through the silica gel hose, and the gas supply device is arranged in the glass cabinet to provide controlled gas, so that the contact between anaerobic bacteria and air is reduced to the greatest extent in the extraction, analysis and gavage processes, and the activity and inhibition effect of the anaerobic bacteria are effectively maintained.

The invention relates to ackermann bacteria tablets for reducing blood sugar. The ackermann tablet is obtained by embedding human symbiotic anaerobic cenobium into a microcapsule prefabricated material to obtain a medicine ball and then tabletting the medicine ball, and the microcapsule prefabricated material is prepared from the following raw materials in parts by weight: 20-25 parts of sodium alginate, 6-10 parts of pectin, 10-18 parts of chitosan and 8-13 parts of sugar-free xylitol; the human body symbiotic anaerobic cenobium is prepared from the following raw materials in parts by weight: 60 to 80 parts of Ackermann muciniphile, 45 to 60 parts of lactobacillus and 30 to 40 parts of bifidobacterium. The ackermann tablet can effectively reduce blood glucose and prevent diabetic complications, the viable count in microcapsules of the tablet reaches 1.57 * 10 <-7 > CFU / g after four weeks and is higher than the minimum sales standard of microecologics related to the international dairy alliance, and therefore the ackermann tablet serves as an important mode for guaranteeing the action activity of ackermann mucophile and has good application prospects. The medicine effect can be obviously improved, the gastrointestinal flora stability of a patient is maintained, and the incidence rate of secondary gastrointestinal diseases is reduced.

The utility model discloses an anaerobic reaction device for white spirit brewing wastewater treatment, which comprises a reaction box, one end of the upper part of the reaction box is provided with a sewage inlet in a penetrating manner, the outer end of the reaction box is provided with a heating sleeve, two ends of the upper part of the reaction box are fixedly connected with air cylinders, the extension ends of the air cylinders are fixedly connected with a connecting plate, and the connecting plate is fixedly connected with the sewage inlet. By arranging the heating sleeve on the outer side of the reaction box, sewage and anaerobic bacteria in the reaction box can be heated, the anaerobic reactor has a proper temperature, then the activity of the anaerobic bacteria is greatly improved, meanwhile, the driving assembly is arranged to drive the internal scraper to rotate, stirring operation is carried out, and the stirring efficiency is improved. Under the cooperation of a rotating assembly and an air cylinder assembly, the two scraping plates can be tightly attached to the inner wall of the reaction box, a worker opens a driving structure to drive the scraping plates to rotate, the inner wall of the reaction box is cleaned through a cover plate, stubborn dirt can be effectively removed, the effluent quality of the anaerobic reactor is guaranteed, and the applicability is high.

The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals.

The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals.

The present invention relates to the technical field of medical devices, and discloses a device for extracting and processing anaerobic bacteria from micro-aerobic intestinal contents, comprising a cabinet, the interior of which is hollow, an operating table provided on the top of the cabinet, a cavity provided at the bottom inside the operating table, and control structures provided on the front and back of the operating table. The device for extracting and processing anaerobic bacteria from micro-aerobic intestinal contents provided by the present invention has a control structure and an air-drying structure, both of which are started by a scraper, which is started by a motor control and then scrapes dirt from the surface of the operating table to one side. While scraping, the control structure also drives a flap to open, allowing dirt to fall onto the baffle. As the scraper moves backward, the flap rotates and closes, and the baffle is opened to allow dirt to fall into a collection box. The setting of the double opening and closing doors can ensure that the gas environment in the sealed box is not destroyed, thereby increasing detection accuracy.

The present invention relates to microbial cells, including but not limited to aerobic bacteria cells and anaerobic bacteria cells, as well as yeast cells, and methods for producing the cells, feed additives and compositions comprising the cells, and uses involving administration of the cells to animals.

This paper describes an oxygen preparation for the treatment of acne and wounds, as well as its preparation method and application device. The oxygen-containing preparation comprises an oxygen bag containing an oxygen-containing pouch. The pouch wall is permeable to oxygen and has an airtight section for controlling the oxygen transfer and diffusion rate, or alternatively, the pouch wall is permeable to oxygen and has an airtight section for controlling the oxygen transfer and diffusion rate. The airtight section has a thickness of 5-500 μm, and the oxygen permeability of the airtight section is 0.0000001 cm2·s·0.1 MPa-0.1 ml / cm2·s·0.1 MPa. This oxygen-containing preparation not only provides oxygen molecules to acne and wound surfaces, killing anaerobic bacteria and promoting wound healing, but also provides oxygen partial pressure and oxygen tension, ensuring oxygen content throughout use. Furthermore, the gas exchange mechanism allows for the exchange of carbon dioxide with cells, enhancing the therapeutic effect.

Plant for the production of a biogas mixture from soy whey, with a bioreactor with anaerobic bacteria, in particular a UASB or EGSB.

The presently disclosed subject matter provides methods and kits for treating solid tumors in a subject by using a combination of anti-CTLA-4 and / or anti-PD-1 antibodies with at least one member of the group consisting of a bacterium, bacterial product, and an immunoregulatory entity. In particular embodiments, the bacteria are toxin-depleted, anaerobic bacteria, such as Clostridium novyi-NT.

The present invention relates to an Alzheimer's disease marker and risk prediction model based on intestinal flora. The Alzheimer's disease marker based on intestinal flora includes intestinal flora, and the intestinal flora includes anaerobic Lawsonia sibiricum, Escherichia coli, Streptococcus salivarius, Asahidiella pseudomallei, Kluyveromyces pedis, intestinal Roseburia, Roseburia faecalis, Roseburia hominis, Firmicutes CAG424 bacteria and Clostridium CAG58 bacteria. The present invention mines Alzheimer's disease markers based on intestinal flora and further constructs an Alzheimer's disease risk prediction model based on intestinal flora, which has the characteristics of high detection accuracy, convenience, speed, safety and non-invasiveness, and has important clinical guidance significance for assisting the diagnosis of Alzheimer's disease-related indicators.