19results about How to "Good hemostatic effect" patented technology

This invention belongs to the field of biomedical materials technology, specifically relating to a chitosan hemostatic sponge and its preparation method. This patent addresses the problems of residual acetic acid and side reactions, low strength, and low absorbency caused by cross-linking methods during the preparation of chitosan hemostatic sponges. It innovatively proposes a method for physically cross-linking chitosan hemostatic sponges using hydrogen bonding-electrostatic synergistic superabsorbency based on alcohol-regulated substances. By introducing alcohols to regulate the electrostatic interaction between chitosan amino groups and acetic acid, while simultaneously adjusting the hydrogen bonding interaction between chitosan molecules, and introducing other polymer materials to construct a semi-interpenetrating network, the overall material properties are enhanced. The chitosan hemostatic material prepared by this process, although without the addition of cross-linking agents, still exhibits an insoluble sponge-like structure, good flexibility, and excellent absorbency and hemostatic effect.

The application provides a first-aid hemostasis robot and a control method thereof. The first-aid hemostasis robot comprises a robot main body capable of walking on the ground, a mechanical arm with multiple degrees of freedom arranged on the robot main body, a pressing head and a blocking piece arranged on the mechanical arm, the pressing head is used for pressing and hemostasis of a blood vessel of a bleeding port, the blocking piece is carried by a flexible continuum robot, a front end of the continuum robot is provided with a camera used for collecting information of a bleeding site, the blocking piece can be inserted into the inside of the bleeding port through the continuum robot and expanded after blocking the bleeding port to seal a large blood vessel of the bleeding port. The mechanical arm carries the pressing head and the blocking piece to perform hemostasis on different conditions of large bleeding respectively, if the bleeding is of a split type, the pressing head is used for pressing and hemostasis at a proximal end of an artery bleeding or a distal end of a vein bleeding, if the bleeding is of a broken type, the blocking piece is inserted into a wound through the continuum robot to seal a large blood vessel of the bleeding.

The utility model discloses a kind of laser device and laser therapeutic instrument, including first laser, second laser, beam synthesis subassembly and optical fiber;The first laser is used for emitting holmium laser towards the beam synthesis subassembly;The second laser is used for emitting thulium laser towards the beam synthesis subassembly;The beam synthesis subassembly is used to beam combining the holmium laser emitted by the first laser and the thulium laser emitted by the second laser into mixed light beam, and the mixed light beam is output to the optical fiber.Wherein, laser device can generate the mixed light beam of holmium laser and thulium laser when working to beam combining, and mixed light beam is guided to target position (such as the region needing treatment) by optical fiber, so that corresponding treatment can be carried out using mixed light beam, so that the treatment effect of holmium laser and thulium laser can be considered.

The embodiment of the invention provides a clip instrument and a control method thereof. The clip instrument includes: a clip arm; the storage tube is used for storing the near end of the clamping arm; the near end of the storage tube is in releasable connection with the far end of the sheath tube; when the clamping arms move from the far end to the near end, the storage tube and the sheath tube can be directly actuated to be released, and / or the clamping arms and the storage tube can be directly actuated to be locked.

This invention relates to a urinary catheter for post-prostatectomy, comprising an outer sheath, a catheter disposed inside the outer sheath, and an expansion component disposed on the surface of the outer sheath. Compared with the prior art, this invention, through the protruding structure on the surface of the balloon, allows the doctor to achieve hemostasis on the wound after prostatectomy via the balloon. The protruding structure can closely fit the uneven interior of the wound after surgery, resulting in better hemostasis compared to the smooth balloon surface in the prior art. At the same time, since the interior of the protrusion is connected to the interior of the balloon, the expansion size of the protrusion during the balloon inflation phase can be affected by the unevenness of the wound surface, avoiding excessive pressure on the post-operative wound area. In addition, the design of multiple sub-protrusions can increase the contact area after the balloon is filled with water or air, resulting in better compression hemostasis.

The application relates to a spinning fiber and a preparation method thereof. The spinning fiber is prepared from raw materials including polyvinyl alcohol and chitosan in a mass ratio of (6-8):(2-4) through solution jet spinning of a mixed crosslinked product of the raw materials. The application provides a spinning fiber which is prepared from a mixed and crosslinked product of chitosan and polyvinyl alcohol in a specific mass ratio through solution jet spinning. The polyvinyl alcohol has better hydrophilicity than the chitosan, and the chitosan has a network structure after interpenetration and crosslinking with the polyvinyl alcohol, so that the hydrophilicity of the chitosan is improved, the swelling degree is increased, the hemostatic effect is better, the effusion of a wound can be effectively absorbed, the wound can be dried, and bacterial reproduction can be prevented.

The utility model provides a kind of composite medical cotton yarn pad, including base layer and the absorption layer being set to the upside of base layer, the middle part of absorption layer is provided with shallow groove, shallow groove is provided with hemostatic layer, hemostatic layer protrudes absorption layer, the upside of absorption layer is covered with release paper, release paper completely covers hemostatic layer, the downside of base layer or the edge of absorption layer is provided with fixing part.The composite medical cotton yarn pad has the advantages of scientific design, easy operation, good hemostatic effect, and is convenient for use in hemostatic medicine application process.

The application discloses a posterior naris filling device with a ventilation tube, which comprises a blind end, a ventilation tube body and a filling capsule body, wherein the filling capsule body is fixedly arranged in the blind end and covers three fourths of the surface of the blind end; a ventilation hole is arranged in the region of the blind end which is not covered by the filling capsule body; and the rear end of the blind end is communicated with the ventilation tube body. The posterior naris filling device with the ventilation tube is inserted into the nasal cavity and the nasal meatus or the inferior nasal meatus, the filling capsule body fills the posterior naris, the ventilation tube body supplies air to the rear end of the nasal cavity of the patient through the ventilation hole of the blind end, the pain of the patient during the filling process and after the filling is reduced, the blind end is adapted to the shape of the nasopharynx and is fixed by the filling capsule body, and the blind end is not easy to move with the swallowing activity, so that the patient can also breathe through the nose after the filling, the discomfort after the filling is greatly reduced, and the treatment effect and the comfort of the hemostasis by filling are greatly improved.

This invention relates to a two-component cross-linked oxidized nanocellulose spray hemostatic gel, its preparation method, and its application, belonging to the field of biomedical materials. Addressing the problems of weak adhesion, insufficient mechanical properties, and biocompatibility risks in existing hemostatic materials, this invention introduces aldehyde groups using sodium periodate to prepare an adhesive component (TOCN-CHO), and simultaneously modifies the carboxyl groups of TOCN with lysine to create a cross-linking component (TOCN-Lys). After the two components are sprayed and mixed, the aldehyde groups of TOCN-CHO bind to the amino groups on the tissue surface to achieve wound sealing. Simultaneously, the amino groups of TOCN-Lys form a Schiff base cross-linking network in situ with the aldehyde groups of TOCN-CHO, enhancing mechanical strength while eliminating aldehyde toxicity. The gel retains shear-thinning properties and can be sprayed. Animal experiments show that the hemostasis time is reduced to 28 seconds. It also exhibits biodegradability and renewability, effectively solving the problem of synergistic optimization of adhesion, mechanical strength, and biocompatibility, making it suitable for emergency hemostasis and surgical scenarios.

The application discloses a hemostatic device applied to various irregular wounds and belongs to the technical field of medical first-aid equipment, which comprises a solid syringe and a medical polyvinyl alcohol sponge strip; the medical polyvinyl alcohol sponge strip can be axially and radially expanded and is punched into a wound by the device, and the sponge strip is used for omnibearing compression hemostasis; meanwhile, the segmented design of the sponge strip allows the selection of a proper number of segments according to the actual length of the wound, so that the wound can be completely covered; after the sponge strip enters the wound, the sponge strip rapidly absorbs blood and expands, generates uniform pressure, effectively seals blood vessels and achieves the purpose of hemostasis; the radial and lateral expansion of the hemostatic sponge strip is realized, the irregular wound is fully covered, the hemostasis effect is remarkably improved, the segmented design makes the hemostatic device capable of flexibly adapting to wounds of different sizes and shapes, the use of additional cutting tools is reduced, the operation process is simplified, the efficient hemostasis mechanism shortens the treatment time, reduces the risk and discomfort of patients and improves the success rate of first aid.

This invention discloses a method for forming a tourniquet for hemostasis of fingers or toes, and the tourniquet thereof. The method includes: forming a main air bladder pre-filled with gas; forming an auxiliary air bladder located on one side of the main air bladder, pre-filled with gas that can be squeezed into the inner cavity of the main air bladder, and whose inner walls can be fixedly connected together after the gas is squeezed out; forming a fixing band on the outside of the auxiliary air bladder and the main air bladder, respectively fixedly connected to the outer surfaces of the two air bladders and respectively provided with connectors at both ends; when stopping bleeding of fingers or toes, fixing the fixing band and the two air bladders inside to the site of hemostasis of the finger or toe by a pair of connectors of the fixing band, squeezing the auxiliary air bladder to allow the pre-filled gas inside to enter the main air bladder and mix with the pre-filled gas inside the main air bladder to apply pressure to the site of hemostasis. The tourniquet of this invention has a simple structure, is easy to use, can accurately locate and stop bleeding at the site of hemostasis for patients undergoing finger or toe surgery, is not easily displaced, provides rapid and effective hemostasis, has low manufacturing cost, and is easy to promote.

The invention relates to the technical field of photo-thermal composite materials, in particular to a hemostatic and antibacterial kaolin / molybdenum sulfide photo-thermal composite material and a preparation method and application thereof. The invention discloses a hemostatic and antibacterial kaolin / molybdenum sulfide photo-thermal composite material which comprises kaolin and metal 1T-phase MoS2 loaded on the kaolin. The preparation method comprises the following steps: dissolving a molybdenum source and a sulfur source in deionized water, adding kaolin, carrying out a hydrothermal reaction, centrifuging, washing, and drying to obtain the hemostatic and antibacterial kaolin / molybdenum sulfide photo-thermal composite material. According to the preparation method disclosed by the invention, the kaolin with a layered structure and surface charge characteristics is introduced, so that the molybdenum sulfide grows in situ between layers or on the surface of the kaolin body, controllable transformation of the molybdenum sulfide from a 2H phase to a 1T phase is realized, and the 1T molybdenum sulfide can stably exist, so that the composite material with high photo-thermal performance and temperature balance capability is obtained. Molybdenum sulfide is loaded on kaolin, so that the hemostatic performance of kaolin is further improved.

The utility model relates to medical instrument technical field especially a new type hemostasis water bag, including guide pipe, inflatable air bag and hemostasis water bag, the hemostasis water bag fixed connection is in the other end of guide pipe, the middle part outside of guide pipe is equipped with blood absorption cotton pad adhesion structure, the other end of hemostasis water bag is equipped with hemostasis medicament supplement and blood discharge structure. This new type hemostasis water bag, the blood discharge pipe can be first in the communicating head end part access external hemostasis medicament, and the external liquid medicine is along the blood discharge pipe first injected into the through -hole position, and the liquid medicine sprays in the uterus inside through the through -hole can cooperate with medicament and accelerate hemostasis, and the rear side of blood discharge pipe can utilize the needle tube of connecting head connection blood drawing, and the reverse pulling needle tube can along the through -hole of opening and blood discharge pipe and remove the redundant blood discharge, utilize blood discharge pipe can first carry out the supplement of hemostasis medicine, also can control the bleeding in the uterus, effectively realize multiple functions, greatly improve the use effect of new type hemostasis water bag.

The application discloses a device for shaping and hemostasis of an ovary wound surface in surgery, which comprises a mesh bag, a threading loop and a contraction and pressure wire, a plurality of threading loops are uniformly arranged on the contraction opening of the mesh bag, the contraction and pressure wire is wound around the bottom of the mesh bag, and then is respectively led to the two sides along the outer edge of the mesh bag, and is multi-pointly penetrated through the mesh bag wire double helix upwards, after the contraction and pressure wire reaches the edge of the contraction opening of the mesh bag, a section of the contraction and pressure wire is left after each winding half a turn along the threading loop on the contraction opening. The device can minimize the damage and function influence of the residual ovary tissue, and can obtain the shaping and hemostasis effect of the residual ovary tissue wound surface, and has the advantages of simple operation, safety and effectiveness and good hemostasis effect.

The utility model discloses a detachable conductive hemostatic trocar device, including the tubulature, the tubulature and human body cooperation one end intercommunication connection has the extension pipe, the extension pipe is away from the tubulature one end for sharp end and the extension pipe's outside detachable cover has the conductive ring, and, the tubulature is away from the extension pipe one end and is provided with the conductive interface and the tubulature is embedded and is provided with the conductive passage along its length direction, the both ends of conductive passage are electric connection with conductive ring, conductive interface respectively, and, the extension pipe is away from the tubulature one end and is provided with visible module, visible module and external display wired or wireless connection. The utility model has the advantages of adjustable conductive contact area, can effectively improve hemostatic effect and the operating safety and efficiency.

The utility model provides a kind of far end radial artery puncture point compression bandage, the front of first bandage one end is provided with first patch, the middle part of first bandage front is provided with second patch, the back of first bandage other end is provided with third patch, and first bandage back is provided with dressing;One end of second bandage is connected with the edge of first bandage by first elastic belt, and the back of other end of second bandage is provided with fourth patch;One end of third bandage is connected with one side of second bandage by second elastic belt, and the front of other end of third bandage is provided with fifth patch, and the back of third bandage in the position of fifth patch is provided with sixth patch;First patch is connected with fourth patch, second patch is connected with sixth patch, and fifth patch is connected with third patch.The utility model solves the technical problems of uneven compression, inconvenience of fixation, lack of personalized adjustment and high cost of one-time use in the prior art.

The application discloses a kind of composite hemostatic microspheres and preparation method thereof, belong to the field of biomedical materials.The hemostatic microspheres are composed of polysaccharide polymer, inorganic nanoparticles and silk fibroin, the mixing ratio of raw materials is accurately regulated using microfluidic, monodisperse microspheres with hemostatic function are produced in batches by centrifugal spraying, and the particle size of microspheres is uniform and controllable.The polysaccharide polymer gives the microspheres rapid water absorption and film forming properties, the inorganic nanoparticles activate blood coagulation factors by contact, and the silk fibroin promotes wound healing.The application utilizes the double shearing action of microfluidic chip flow channel and centrifugal spraying system flow channel to achieve uniform distribution of inorganic nanoparticles in the superficial layer of microspheres, and the hemostatic effect is remarkable;The film forming property is good, and the risk of distal embolism can be avoided;And it has anti-inflammatory and healing functions, and is suitable for rapid hemostasis of body surface wounds and organ surfaces.

The invention discloses an anti-slip hemostatic sandbag for compressing a bag after a permanent pacemaker operation, and relates to the technical field. An anti-skid hemostasis sandbag used for permanent pacemaker postoperative capsular bag compression comprises a fixing frame, a salt bag is arranged in the fixing frame, the sandbag further comprises an adjusting anti-skid assembly, the adjusting anti-skid assembly is arranged on the inner wall of the fixing frame, and through the arranged adjusting anti-skid assembly, the salt bag can be compressed through the adjusting anti-skid assembly. A threaded column rotates and is matched with the inner wall of a threaded hole through the surface of the threaded column, so that the threaded column moves to extrude a shielding plate, when the shielding plate is extruded, a sliding frame conveniently drives a salt bag in a filling groove to move, and the salt bag moves to conveniently adjust the compression strength of compression hemostasis; meanwhile, the salt bag is arranged on the inner wall of the sliding frame, and the sliding frame is arranged on the inner wall of the fixing frame, so that the salt bag is conveniently limited, and the salt bag is prevented from sliding left and right.

This application specifically discloses a method for preparing carboxymethyl chitosan with a wide molecular weight distribution and its application in hemostasis and repair, comprising the following steps: dispersing chitosan in anhydrous ethanol, adding glacial acetic acid, stirring, adding benzaldehyde, stirring, then adding sodium hydroxide solution and stirring, separating the solid and liquid, washing, and obtaining a wet material; adding the wet material to an ethanol-water solution under cold water bath conditions, adding a strong alkali solution, adding chloroacetic acid solution to react, adding carboxymethyl chitosan to the ethanol-water solution, then adding hydrochloric acid to obtain a powder; dividing the powder into three equal parts, adding hydrogen peroxide solution to anhydrous ethanol, adding the first part of the powder, stirring for 1-1.5 h, then adding the second part of the powder, continuing the reaction for 2-2.5 h, separating the solid and liquid, mixing with the third part of the powder, adding pure water, adding manganese dioxide, stirring, filtering, and drying to obtain the final product. The carboxymethyl chitosan of this application has a wide molecular weight distribution and excellent hemostatic and repair properties.