13537results about "Bandages" patented technology

Sanitary tissue products of the present disclosure may comprise at least about 70% short fibers and / or having a weight weighted mean fiber length of less than about 1.4, and may have one or a combination of premium performance parameter(s). One or more of said sanitary tissue products may form part of an array of sanitary tissue products.

The invention provides temperature and pH responsive hydrogel entrapped with chlorogenic acid lipidosome as well as a preparation method and application of the temperature and pH responsive hydrogel, and relates to the technical field of biology. The temperature and pH responsive hydrogel entrapping chlorogenic acid lipidosome contains chlorogenic acid lipidosome, phenylboronic acid grafted modified gelatin and dopamine grafted oxidized hyaluronic acid, the concentration of the phenylboronic acid grafted modified gelatin is 3-10 wt%, the concentration of the dopamine grafted oxidized hyaluronic acid is 3-10 wt%, and the concentration of chlorogenic acid is 1-20 [mu] M. The temperature and pH responsive hydrogel can effectively promote wound healing independently or in combination with blue light.

Sanitary tissue products of the present disclosure may comprise at least about 70% short fibers and / or having a weight weighted mean fiber length of less than about 1.4, and may have one or a combination of premium performance parameter(s). One or more of said sanitary tissue products may form part of an array of sanitary tissue products.

Absorbent articles with front and rear opening features are disclosed. An article may comprise an insert comprising an outer cover, a liner, and a core between the outer cover and liner, a first waist panel coupled to the insert throughout a first attachment region, and a second waist panel coupled to the insert throughout a second attachment region, the second panel being coupled to the first panel proximate a first side edge of the article and the second side edge of the article and further comprising a weakened region. The second attachment may comprise a low-strength attachment zone and a high-strength attachment zone, the high-strength attachment zone disposed proximate the attachment region bottom edge. The low-strength attachment zone may further have a first peel strength and the high-strength attachment zone may have a second peel strength, the second peel strength greater than the first.

The invention relates to the technical field of medical instruments, and provides a vacuum sealing drainage dressing and a wound surface treatment device.The vacuum sealing drainage dressing comprises a sealing layer and a dressing layer which are sequentially arranged in a stacked mode from top to bottom, and further comprises a drainage assembly; the drainage assembly comprises a sucker and a drainage tube, the sucker is arranged at the adsorption opening of the sealing layer, and the drainage tube is connected to the sucker; the dressing layer is of a porous structure, hole walls are communicated with one another to form a continuous channel, the dressing layer is provided with a flexible plasma patch, the flexible plasma patch is suitable for generating plasma acting on a wound surface, and the flexible plasma patch is provided with through holes communicated with pores. The flexible plasma patch is integrally arranged on the dressing layer, negative pressure drainage and wound sterilization and disinfection combined healing promoting treatment can be achieved, the wound or wound treatment process can be simplified, inconvenience caused by frequent dressing change is reduced, and the faster and better healing effect is achieved.

Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. Systems included herein provide an airflow to the patient in additional to a liquid flow that define a thermal energy exchange with the patient. Various systems may provide air at a defined TTM temperature to a thermal contact pad, a mattress or a ventilator that delivers the TTM air to the patient via the ventilation therapy. Also disclosed herein are systems, devices, and methods for preventing, managing, and / or removing perspiration moisture from between the thermal contact pad and the patient. Disclosed herein is a thermal contact pad includes a wicking material to draw moisture away from the patient. Disclosed herein also is a thermal contact pad including airflow that draws moisture away from the patient.

The invention relates to the field of disposable hygienic products, in particular to a high-diffusion baby paper diaper and a preparation method thereof.The prepared baby paper diaper has the advantages of being good in flow guide effect and high in absorption efficiency. The absorption core layer comprises a top layer non-woven fabric, a middle non-woven fabric, a bulky non-woven fabric, a bottom layer non-woven fabric, a wood pulp fiber layer, a first absorption material layer and a second absorption material layer, the first absorption material layer comprises first polymer water-absorbent resin particles and first wood pulp fibers, and the second absorption material layer comprises second polymer water-absorbent resin particles. The second absorbing material layer is arranged between the bulky non-woven fabric and the bottom layer non-woven fabric, part of the second macromolecule water-absorbent resin particles on the second absorbing material layer are embedded in pores of the bulky non-woven fabric, and the first absorbing material layer is arranged between the bulky non-woven fabric and the middle non-woven fabric. And a part of the first high-molecular water-absorbent resin particles on the first absorbing material layer are embedded in pores of the bulky non-woven fabric.

The invention relates to the technical field of skin care, in particular to a collagen composition with anti-wrinkle and repairing effects and a preparation method. Comprising 1.5-4.5 parts of mixed collagen, 2.5-5 parts of mixed polypeptide and 4-8 parts of mixed extract, wherein the mixed extract comprises 1-2 parts of centella asiatica extract, 1-2 parts of polygonum cuspidatum root extract, 1-2 parts of bilberry fruit extract and 1-2 parts of bidens pilosa extract; the collagen is directly supplied to the skin to supplement collagen, and is mainly used for repairing the skin structure, increasing the density, elasticity and compactness of the skin and remarkably improving fine wrinkles and looseness; the polypeptide inhibits the expression of MMP-1; the natural plant active ingredients promote the expression of TGF-beta, enhance the activity of fibroblasts, accelerate the synthesis of collagen, prevent excessive oxidation of skin, repair skin inflammation, activate cell energy and delay skin aging.

An absorbent article having a front edge intended to be positioned at a front side of a person and a rear edge intended to be positioned at a rear side of a person, said absorbent article comprising a liquid pervious topsheet, a liquid impervious backsheet, and an absorbent material between said topsheet and said backsheet, wherein at least a first spacer element is included between said topsheet and said backsheet, wherein the first spacer element has a top side facing the topsheet, a bottom side facing the backsheet, and a number of lateral sides between the top and the bottom side, and wherein the absorbent material extends along at least two opposite lateral sides of the first spacer element; said first spacer element being configured to guide liquid to the absorbent material upon wetting of the absorbent article.

The invention discloses a double-layer surface layer centrally-compounded urine and excrement combined absorption paper diaper and a production process thereof, and relates to the technical field of absorption products, the double-layer surface layer centrally-compounded urine and excrement combined absorption paper diaper comprises a paper diaper main body and a waistline area, the paper diaper main body comprises a surface layer, an absorption core body and a bottom layer, the absorption core body is clamped between the surface layer and the bottom layer, and the waistline area is arranged between the surface layer and the bottom layer; the waistline area comprises a front waistline area and a rear waistline area, the skin-friendly hot-air non-woven fabric surface layer of the surface layer can quickly lock urine and guide flow through the rhombic groove area, the air permeability is enhanced in combination with the salient point punching area, and the contact surface is kept dry and comfortable; the absorption core body adopts an ultrasonic edge compounding and middle hot melt adhesive combined process, so that the adhesive amount is reduced, a water absorption expansion space is reserved, and liquid permeation is accelerated; the bottom layer is compounded with the waterproof breathable film through micropore treatment, a double-micropore structure is formed, and the bottom breathability is greatly improved on the basis of blocking liquid leakage. The overall design realizes triple improvement of flow guide efficiency, air permeability and skin comfort through structural optimization.

The invention belongs to the technical field of biomedical materials, and relates to ultrasonic response adhesion integrated hydrogel as well as a preparation method and application thereof, the hydrogel comprises a hydrogel matrix, an interface anchoring agent and a functional load component; the preparation method comprises the following steps: 1, preparing a hydrogel precursor solution, and preparing a hydrogel matrix into a solution; 2, carrying out mold molding or injection crosslinking on the solution prepared in the step 1 to form hydrogel; 3, preparing an interface anchoring agent solution, and dissolving or dispersing an interface anchoring agent in a solvent to prepare the interface anchoring agent solution; the ultrasonic responsive adhesive hydrogel platform provided by the invention can provide an efficient, controllable and universal solution for tissue adhesion, targeted therapy, wearable attachment and the like in a complex microenvironment, and is suitable for a plurality of clinical scenes such as chronic wound management, surgical postoperative closure, infection control, adhesive bioelectronic fixation, soft tissue engineering and the like.

An improved fecal incontinence leak prevention underwear or undergarment designed to address the challenges faced by individuals with fecal incontinence, including the risk of leaks and stains on clothing is described. The rear surface of the underwear or undergarment has a multi-layered rear surface adapted to cover a buttock region of the wearer. The multi-layered portion is strategically designed to extend from the crotch region to the cleft of a wearer. The multi-layered portion comprises an innermost layer made from moisture-resistant fabric, a middle layer of absorbent terrycloth material, and an outer layer consistent with standard underwear or undergarment materials, typically cotton (i.e., fabric). In one embodiment, the multi-layered portion has varied density to accommodate different levels of protection and comfort.

A package of one or more absorbent articles is provided. The package comprises a package material comprising natural fibers. The package comprises a plurality of panels comprising a consumer-facing panel. The package is sealed such that the one or more absorbent articles are enclosed therein. The package material exhibits a HuBa value of greater than about 5.3 hours, according to the HuBa Test. The package is recyclable. The package comprises a vertical side seal having a side seal strength. The side seal strength is greater than about 5.1 N / 15 mm and less than about 15 N / 15 mm, according to Seal Tensile Strength Test.

The invention relates to the technical field of microorganisms, and provides lactobacillus mucilaginosus for maintaining genital tract health and preventing genital tract infection and application of lactobacillus mucilaginosus. Fermented mucus lactobacillus for maintaining genital tract health and preventing genital tract infection is named as FMTA1113H and is preserved in China General Microbiological Culture Collection Center (CGMCC) on April 22, 2025, the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC NO.34291. The invention further discloses a preparation method of the fermented mucus lactobacillus for maintaining genital tract health and preventing genital tract infection. According to the technical scheme, the problems that female genital tracts are prone to infection and relapse is prone to occurring after infection in the prior art are solved.

The invention belongs to the technical field of protein engineering and biology, and discloses a recombinant III-type humanized collagen, a coding gene thereof, a protein preparation, a preparation method of the protein preparation, application of the protein preparation and a skin care product. The amino acid sequence of the recombinant III type humanized collagen is as shown in SEQ ID NO. 1. According to the recombinant III type humanized collagen, the transdermal absorption efficiency is greatly improved, and meanwhile, the proliferation and migration capabilities of keratinocytes are also remarkably improved. The collagen is widely applied to the fields of medical cosmetic plastic surgery, cosmetics and the like, and has a good application prospect.

The invention discloses an anti-degradation recombinant collagen as well as a preparation method and application thereof, and belongs to the technical field of collagen and bioengineering. According to the invention, full-length or partial genes of natural collagen in a human body are selected for certain optimization combination, a collagen amino acid sequence with strong stability and high biological activity is designed, and the amino acid sequence is completely consistent with a sequence of a corresponding region of the natural collagen in theory, and has relatively low immunogenicity; and the collagen has typical biological functions of human body collagen. The recombinant collagen prepared by the invention has excellent stability, biological activity and safety.

The invention discloses an antibacterial peptide and application thereof, and belongs to the technical field of biology. The antibacterial peptide with an inhibition effect on various clinically common pathogenic microorganisms is obtained, and the antibacterial peptide comprises gram-negative bacteria such as escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, acinetobacter baumannii, vibrio parahaemolyticus, salmonella gallinarum, salmonella typhimurium and enterobacter sakazakii, and gram-positive bacteria. The antibacterial peptide provided by the invention can be used as an antibacterial peptide, such as staphylococcus aureus, listeria monocytogenes and bacillus cereus, and the antibacterial peptide provided by the invention is novel in structure and easy to prepare.

An absorbent article comprising a hotmelt adhesive comprising a styrene-block-copolymer (SBC), an amorphous polyolefin and optionally a tackifier. The SBC is preferably selected from the group of SEBS, SEPS and SEP polymers, and the amorphous polyolefin is preferably a propylene-based copolymer (PbP) having a weight-average molecular weight Mw of less than 10 000 g / mol. The hotmelt adhesive bonds two components of the article, for example SAP particles on the core wrap.

The invention relates to a preparation method and application of a Janus structure photo-thermal-piezoelectric hydrogel dressing for infected wound repair, and the preparation method comprises the following steps: respectively dissolving phenylboronic acid grafted methacrylamide gelatin and dopamine grafted hyaluronic acid in deionized water, adding MXene coated CeO2 heterojunction, and ultrasonically dispersing uniformly, so as to obtain the Janus structure photo-thermal-piezoelectric hydrogel dressing for infected wound repair. After mixing, sodium hydroxide is used for adjusting the pH value to alkalescence, and a Janus structure inner layer is formed; respectively dissolving phenylboronic acid grafted gelatin and o-nitrobenzyl alcohol grafted hyaluronic acid in deionized water, adding BaTiO3, ultrasonically dispersing uniformly, and mixing to form a Janus structure outer layer; the Janus structure photo-thermal-piezoelectric hydrogel dressing prepared by the invention has the characteristic of space-time release so as to adapt to the wound repair process, in addition, the Janus structure photo-thermal-piezoelectric hydrogel dressing also has excellent photo-thermal conversion performance, bacteria infecting the wound are killed through photo-thermal heating, physiological electric signals are effectively simulated through the piezoelectric effect, cell behaviors are regulated and controlled, and the Janus structure photo-thermal-piezoelectric hydrogel dressing can be used for wound infection repair.

The invention discloses a hydrogel wound dressing for promoting healing of infectious wounds. The hydrogel wound dressing is prepared from the following raw materials: oxidized methacrylic acid hyaluronic acid, waterborne polyurethane, polylysine, cannabidiol, neomycin sulfate and 2-roots alcohol. The invention also provides a preparation method of the hydrogel wound dressing and application of the hydrogel wound dressing in preparation of products for repairing infectious wounds. The wound dressing provided by the invention has a microporous structure, good biocompatibility and biodegradability, and can be used for stopping bleeding, reducing wound infection and promoting cell proliferation and wound healing.

The invention discloses a Janus wound dressing with antibacterial and tissue repair promoting functions and a preparation method of the Janus wound dressing, belongs to the technical field of wound dressings, and aims to realize antibacterial, tissue repair promoting and moist wound healing microenvironment through freeze drying and electrostatic spinning technologies. Polycaprolactone (PCL), bioactive glass (BG) and curcumin Cur are used for preparing a hydrophobic inner layer capable of promoting tissue repair, methacrylated gelatin GelMA is used for preparing a hydrophilic outer layer with moisturizing performance, and the PCL-BG-Cur / GelMA composite wound dressing with antibacterial, moisturizing and repair promoting functions is constructed. Animal experiment results show that the dressing loaded with curcumin Cur and bioactive glass BG has multiple functions of synergistic antibiosis, moisturizing and the like, the result shows that the prepared dressing has the performance of promoting epithelization, collagen deposition, new hair follicle formation and the like, and the dressing has a considerable application prospect in the aspect of rapid wound repair.

The invention belongs to the field of biological materials, and particularly relates to recombinant V-type humanized collagen and application thereof. The invention provides a recombinant V-type humanized collagen, the amino acid sequence of the recombinant V-type humanized collagen comprises (repetitive unit) n, and the repetitive unit comprises a sequence as shown in SEQ ID NO.1; each repeating unit is directly linked and the number n of repeating units is 10. The recombinant V-type humanized collagen can comprehensively resist skin aging.

The invention provides an intelligent response type medical liquid application and a preparation method thereof, and relates to the technical field of medical dressings. The liquid application is composed of a basic repairing component, a natural antibacterial component, a plant active component, an intelligent carrier system and auxiliary materials. Accurate release of active ingredients is realized by adopting a pH / temperature double-response intelligent delivery system, and the transdermal absorption rate is remarkably improved; wound healing is accelerated through the synergistic effect of the compound protein and the plant extract; active ingredients are effectively reserved through a multi-mode sterilization process. The liquid application disclosed by the invention has the characteristics of strong antibacterial property, good environmental adaptability, excellent healing effect and the like.

The invention relates to the technical field of biology, and particularly discloses a recombinant collagen III and application thereof in preparation of gel. The recombinant collagen III is designed by optimizing functional area sequences of human I-type and III-type collagen, the amino acid sequence is shown as SEQ ID No.2, and the recombinant collagen III has the characteristics of high stability, good hydrophilicity and low immunogenicity. The preparation method comprises the steps of expression vector construction, escherichia coli induced expression, affinity chromatography purification and renaturation. The recombinant collagen III can be prepared into a gel dressing and comprises sodium alginate, methylparaben and other components. Experiments show that the gel can effectively promote cell proliferation and has no cytotoxicity; in a mouse skin injury model, the collagen can relieve inflammation, accelerate wound healing and inhibit scar formation, and the effect of the collagen is superior to that of natural human III-type collagen. The invention provides a safe and efficient novel material for wound repair, and is suitable for medical dressings and tissue engineering.

A method of manufacturing an absorbent core for a disposable absorbent hygiene article includes providing a first core cover web and at least one pleat in the first core cover web; applying an adhesive to the pleated first core cover web; bringing the pleated first core cover web into conformance with a recess, the recess including at least one channel-forming element arranged on a bottom surface of the recess and causing the pleat to at least partially unfold at the channel-forming element; applying absorbent material on the first core cover web in the recess; applying an adhesive on a second core cover web; applying the second core cover web to the first core cover web; forming an absorbent laminate by pressing together the second and first core cover webs; and forming individual absorbent cores by severing the absorbent laminate. An absorbent core and an absorbent article including the absorbent core are also disclosed.

The invention discloses a self-healing injectable photo-crosslinking dual-network hydrogel and a preparation method thereof.The preparation method comprises the steps that silk fibroin is subjected to methacrylation modification through a glycidyl methacrylate solution, then dextran of the silk fibroin is subjected to an oxidation reaction through a sodium periodate solution, oxidized dextran is generated, and the self-healing injectable photo-crosslinking dual-network hydrogel is obtained; the amino group in the modified silk fibroin and the aldehyde group of the oxidized dextran are subjected to a Schiff base cross-linking reaction to form the double-network hydrogel. The hydrogel with the double-network structure prepared by the invention is more compact in structure, so that the hydrogel has a series of excellent performances such as injectability, relatively good adhesion, good mechanical property, self-healing property and slow release property after drug loading while having safety.

The invention discloses hydrogel loaded with antibacterial polypeptide as well as a preparation method and application of the hydrogel. The preparation method of the hydrogel comprises the steps that antibacterial polypeptide and polyethylene glycol dimethacrylate are subjected to a cross-linking reaction, the hydrogel can be obtained, and the antibacterial polypeptide is obtained through polymerization synthesis of a cationic CBL monomer compound and an HBL monomer compound; the hydrogel has remarkable sterilization and anti-biofilm effects, and in-vitro cytotoxicity shows that the antibacterial polypeptide hydrogel product has no inhibition effect on normal cell growth; when the hydrogel dressing is used as a hydrogel dressing and is combined with novobiocin for use, more than 99% of antibacterial effect is achieved in a diabetes wound infection model and a fungal psoriasis infection model; and when being used as a hydrogel preparation to be combined with fluconazole, the compound has the effect of inhibiting growth of more than 99% of fungi in an animal vaginitis model.

The invention belongs to the field of synthetic biology, and particularly relates to collagen fusion polypeptide as well as application and a preparation method thereof. The collagen fusion polypeptide provided by the invention comprises: (a) a first polypeptide of recombinant III-type collagen; and (b) a second polypeptide comprising a trimerized folding domain. The collagen fusion polypeptide provided by the invention has the advantages of low immunogenicity, good biocompatibility, high biological activity and the like, can significantly promote proliferation and migration of human skin fibroblasts, and has stronger ability of promoting regeneration of endogenous collagen. The collagen fusion polypeptide has a triple helix structure similar to natural collagen, and can be self-assembled to form collagenous fibers which are good in morphology and similar to natural collagen. The method can be widely applied to the fields of skin repair dressings, biological materials, artificial implants, medical instruments, cosmetics, health care products, food and the like.

The invention relates to the technical field of bandages, in particular to a composite fiber antibacterial bandage and a preparation method thereof. Carrying out physical crosslinking by utilizing the characteristics that quaternary ammonium salt chitosan is dissolved in positive charges of a water band and sodium alginate is dissolved in negative charges of the water band to obtain antibacterial impregnation liquid; by utilizing the characteristic that polyethylene glycol can effectively prevent bacteria and mould from breeding, polyethylene glycol is connected to the surfaces of the polydopamine nanospheres by adopting a covalent binding method to form a polymer molecular brush so as to obtain an antibacterial impregnation liquid; cotton fibers and polyester fibers are soaked in antibacterial impregnation liquid and antibacterial impregnation liquid respectively to obtain antibacterial fibers and antibacterial fibers, the antibacterial fibers and the antibacterial fibers are co-spun to prepare the bandage with the functions of preventing bacterial adhesion and inhibiting bacteria, and the prepared bandage has a good antibacterial effect; the antibacterial durability is effectively improved.

The invention belongs to the technical field of biological medicines, and particularly relates to hydrogel with photo-thermal multiple antibacterial and hemostatic functions. The multifunctional hydrogel is prepared from epsilon-polylysine (EPL), gallic acid (GA), tannic acid (TA) and ferric trichloride hexahydrate. The polyphenols are obtained through multiple mechanisms such as reaction between the polyphenols and amino groups, metal chelation, pi-pi interaction and electrostatic attraction (as shown in Figure 1). The metal ion and multiple dynamic cross-linking system hydrogel is constructed, the hydrogel with positive charges enriched on the surface can act with blood platelets with negative charges, red blood cell aggregation, blood platelet adhesion and vasoconstriction effects are promoted, and the blood coagulation efficiency is improved. The hydrogel shows excellent antibacterial performance and photo-thermal performance, can prevent infection in the inflammation stage of wound healing, can effectively accelerate wound healing, and has good biological safety.