95 results about "Bioceramic" patented technology

This invention relates to compositions and applications for a bioceramic composition that includes from about 45 to about 55% by weight of kaolinite (Al2Si2O5(OH)4); from about 5 to about 15% by weight of tourmaline; from about 3 to about 13% by weight of aluminum oxide (Al2O3); from about 11 to about 19% by weight of silicon dioxide (SiO2); and from about 3 wt % to about 13 wt % zirconium oxide (ZrO2).

The present invention relates to a medical device manufactured using the additive manufacturing process (3D printing). It is a medical device used preferably as a bone graft composed of a porous structure based on bioceramics based on β-tricalcium phosphate (β-TCP) or hydroxyapatite, which may or not contain nanostructures in its composition, for example: carbon nanostructures (graphene, graphene oxide, reduced graphene oxide, carbon nanotubes, etc.) and, in preferred embodiments, stem cells and polymeric membrane. Also, the present invention relates to the use of this device as a bone graft and the process of preparing this device.

The invention provides porous biological ceramic as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing aluminum oxide slurry with a pore forming agent to obtain mixed slurry; carrying out light curing reaction on the mixed slurry in a layer-by-layer projection manner by adopting DLP 3D printing, and carrying out layer-by-layer printing, accumulation and forming to obtain a ceramic body; according to the preparation method, through the aluminum oxide slurry composite pore-forming agent and the DLP 3D printing technology, it is guaranteed that no through hole exists in the material, high density and mechanical strength are maintained, and the problem that in the prior art, surface performance and mechanical performance are difficult to consider at the same time is solved; a discrete porous structure is constructed on the surface of the high-solid-content aluminum oxide ceramic, so that accurate regulation and control of the surface roughness are realized, surface discrete holes are directly formed, and a complex post-treatment process is omitted; through the sintering process, the overall sintering shrinkage rate is controlled, the forming precision of a complex structure is improved, the large-scale production requirement is met, and the material can be applied to bone tissue engineering scaffolds and tooth restoration materials.

The invention relates to an orthopedic implant surface treatment method based on femtosecond laser. The surface treatment method comprises the following steps: cleaning and drying the surface of the orthopedic implant base material; femtosecond laser treatment is carried out on the surface of the orthopedic implant base material, and regularly arranged microstructures are formed on the surface of the base material; the orthopedic implant base material comprises a metal base material, a biological ceramic base material and a high polymer material base material, the microstructure comprises one or more of a groove, a dot matrix or a grid; and performing plasma spraying of a biological coating on the surface of the orthopedic implant base material subjected to femtosecond laser treatment to finally obtain the surface-modified orthopedic implant. Wherein the biological coating comprises a titanium coating and a hydroxyapatite coating. Compared with the prior art, the bonding force between the plasma spraying biological coating and the orthopedic implant base material is remarkably improved, and the application variety of the orthopedic implant base material is widened.

1. The name of the product under this design: Women’s waist-binding panties (bioceramic temperature-sensitive panties 8801#). 2. Purpose of the product of this design: for clothing. 3. The design key point of this appearance design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: Usage status diagram 1. 5. This design product is a thin product, and other views are omitted.

The application discloses a kind of based on photosensitive bioceramics deciduous tooth additive manufacturing forming process, it is related to ceramic deciduous tooth manufacturing technical field, comprising the following steps: using oral scanner to collect children's dental three-dimensional data, generate deciduous tooth restoration three-dimensional data model and export STL format deciduous tooth repair model;Using photosensitive liquid bioceramic composite material, through DLP photocuring 3D printing into initial blank, again through blue light three-stage resolidification and get blank body.In the process, the morphological characteristics of adjacent healthy deciduous teeth can be accurately extracted, and the crown height correction coefficient is automatically matched according to the age of the child, effectively compensating for the size deviation of the unerupted deciduous teeth, ensuring that the size error of the restoration is small, adjusting the occlusal surface morphology of the restoration according to the actual data of the teeth at the same time, making the occlusal contact area ratio higher, and reserving occlusal buffer space to avoid excessive local stress, significantly improving the mastication comfort and durability of the restoration.

The present application relates to the instrument and method of filling root canal, specifically relates to a kind of self-expanding root canal filling instrument combination based on the concept of root apex biological closure and its using method, for solving the volume shrinkage caused by the existing root canal sealant and gutta-percha point filling after filling, leading to root canal filling failure, and the toxic and harmful ingredients contained in root canal sealant and gutta-percha point itself can bring potential harm to the patient The deficiency, the self-expanding root canal filling instrument combination includes self-expanding composite bioceramic root canal sealant and root canal plug tip;The self-expanding composite bioceramic root canal sealant is composed of liquid agent, powder;The liquid agent is distilled water or physiological saline;The powder is divided into A component, B component;The material of the root canal plug tip is medical pure titanium or titanium alloy.

The application discloses a 3D printing ocular prosthesis platform, which is prepared through the following steps: S1, designing the shape of the ocular prosthesis platform and dividing the shape into regions; S2, selecting a porous structure for the ocular prosthesis platform in each region and determining the voxel size according to the connecting point parameters of the selected porous structure; S3, voxelizing and fitting each region to form a voxelized interface; S4, filling the porous structure selected in step S2 into each corresponding region to complete the modeling of the porous structure in each region; S5, connecting the connecting points on adjacent voxelized interfaces to each other and converting the connecting lines into solid rod models to complete the modeling of the interfaces; S6, merging the models obtained in steps S4 and S5 to obtain a final model of the ocular prosthesis platform; S7, 3D printing to obtain a bioceramic blank; and S8, high-temperature sintering of the blank to obtain a 3D printed ocular prosthesis platform after porcelain forming. The application can obtain a new 3D printed ocular prosthesis platform, which provides technical support for ocular prosthesis repair.

The invention discloses selective laser melting biological ceramic powder for dental restoration and a preparation method thereof, and belongs to the technical field of dental restoration materials. The composite ceramic material comprises the following raw materials in parts by weight: 50-100 parts of composite ceramic powder and 0.1-2 parts of an absorbent, the composite ceramic powder comprises at least two of Al2O3, ZrO2, SiO2 and TiO2; the absorbent comprises any one of TiC, SiC, ZrC, TiN and graphite; the fluidity of the selective laser melting biological ceramic powder for dental restoration is 39-40 s / 50 g. According to the invention, the SLM process adaptability of the material is obviously improved, the inherent biocompatibility, mechanical strength and stability of biological ceramics are considered, and the technical barrier that traditional biological ceramic powder is difficult to be directly used for selective laser melting is overcome; and a feasible material solution is provided for direct additive manufacturing of personalized dental prostheses with high performance and complex structures.

The invention provides a composition for a conductive polymeric material suitable for the production of electrodes for recording electrophysiological signals, such as electrocardiogram (EGG), electromyogram (EMG), electroencephalogram (EEG), etc., and signals related to the impedance variation of the body or skin, both deriving from active and passive measures (for example, breathing, electrodermal response, etc.). For this purpose a formulation containing FEDOT and ionic liquids has been developed. The formulation according to the invention can be used generically in the context of detecting bioelectric signals and can be applied on wearable items, in particular in fabric, such as for example garments of different shapes, so as to be in direct contact with the areas of the body subject to detection. The artifacts include diving artefacts, such as watertight suits, and for water sports and submarine surveys, artifacts used in the medical and health sector such as plasters, elastic support bands and adhesive support bands and textile articles, including special fabrics such as bioceramics.

This invention discloses a preparation method and application of Al2O3 self-reinforced zirconia medical ceramic material, belonging to the field of bioceramic material preparation. The preparation method includes the following steps: first, aluminum particles are surface passivated, then mixed with Y2O3-ZrO2 ceramic powder, a dispersant, and a binder to prepare a slurry; the slurry is obtained through spray granulation and dry pressing; finally, the finished product is obtained through atmosphere sintering, oxygen absorption reaction, and high-temperature sintering. This invention utilizes the volume expansion effect of in-situ generated Al2O3 to artificially introduce a beneficial local compressive stress field into the zirconia matrix, effectively compensating for the phase transformation strengthening effect lost due to increased yttrium oxide content. This achieves a synergistic improvement in the mechanical properties and anti-aging properties of zirconia all-ceramic materials, solving problems such as insufficient anti-aging performance of existing zirconia all-ceramic materials, significant strength decrease after adding yttrium oxide, and insufficient strengthening effect of traditional Al2O3 second-phase addition.

The invention belongs to the technical field of zirconium oxide biological ceramics, and particularly relates to a preparation method and application of zirconium oxide biological ceramics. The preparation method comprises the following steps: firstly, preparing porous hydroxyapatite of which the pore surface is loaded with silver nitrate, then preparing polycaprolactone-coated silver nitrate-loaded porous hydroxyapatite, and then preparing a polycaprolactone-coated silver nitrate-loaded porous hydroxyapatite / zirconium oxide compound; then mixing the polycaprolactone coated silver nitrate loaded porous hydroxyapatite / zirconium oxide compound with an auxiliary agent, homogenizing to obtain uniform slurry, performing injection molding on the slurry to obtain a ceramic green body, finally putting the ceramic green body into a sintering furnace, performing programmed heating and heat preservation, and naturally cooling to room temperature to obtain the zirconium oxide biological ceramic. The zirconium oxide biological ceramic obtained by the invention combines good biological activity of hydroxyapatite and excellent mechanical properties of zirconium oxide, is not easy to wear, scratch and the like, and can maintain the form and function of a ceramic ferrule for a long time.

The invention discloses a polyethylene composite fiber as well as a preparation method and application thereof. The polyethylene composite fiber comprises ultra-high molecular weight polyethylene fiber and biological ceramic, and can be used for surgical suture and repair products. The surgical suture and repair product is mainly used for bone suture and repair, promotes bone growth and repair at a wound, and is beneficial to bone healing. The surgical suture and repair product is high in strength, safe, reliable, good in biocompatibility, beneficial to bone wound healing, not prone to adhesion to bone tissue and easy to detach.

The invention relates to a living plant cell-animal cell composite scaffold as well as a preparation method and application thereof. The living plant cell-animal cell composite scaffold comprises a 3D printing hydrogel scaffold used as a muscle repair carrier and a 3D printing biological ceramic scaffold used as a bone repair carrier, wherein the 3D printing hydrogel scaffold and the 3D printing biological ceramic scaffold are assembled by simulating a muscle-skeleton structure; the hydrogel scaffold comprises a polymer matrix component, and functional plant cell components, namely diatom cells and mammalian cell components, namely muscle stem cells, which are distributed in the polymer matrix component, the biological ceramic scaffold comprises a biological ceramic scaffold matrix component and mammalian cell component bone marrow mesenchymal stem cells inoculated and loaded on the biological ceramic scaffold matrix component.

The invention belongs to the technical field of macromolecular biological materials, and particularly provides a preparation method of a polyether-ether-ketone material, which comprises the following steps: 1) pretreating polyether-ether-ketone, cleaning the surface and removing surface burrs; 2) performing surface high-temperature carbonization treatment on the pretreated polyether-ether-ketone to carbonize the surface of the polyether-ether-ketone to form a carbonized layer with a porous structure; (3) carrying out surface deposition treatment on the modified polyether-ether-ketone obtained in the step (2), and directly depositing a carbide coating on the surface of the carbonization layer with the porous structure or depositing and constructing a metal coating, a biological ceramic coating and a polymer coating on the surface of the carbonization layer; 4, the modified polyether-ether-ketone obtained in the step 3 is subjected to aftertreatment to eliminate surface residual stress, and the polyether-ether-ketone material with the high biological activity is obtained.The polyether-ether-ketone material has good biocompatibility and biological activity and can meet the clinical requirements of the medical field.

The invention discloses a double-layer tissue engineering drug-loaded stent as well as a preparation method and application thereof. The invention firstly discloses a double-layer stent for a soft and hard tissue interface, wherein the double-layer stent comprises a bone tissue regeneration layer and a fibroblast migration barrier layer; the raw materials of the bone tissue regeneration layer comprise at least two polysaccharide materials with the concentration of 15-25 mg / mL and a biological ceramic material with the concentration of 10-20 mg / mL, and the bone tissue regeneration layer has a loose and porous structure; the raw materials of the fibroblast migration barrier layer comprise at least two polysaccharide materials with the concentration of 25-35 mg / mL, and the fibroblast migration barrier layer is of a compact layer structure. The double-layer tissue engineering drug-loaded stent disclosed by the invention is prepared from osteogenic drugs and / or antibacterial drugs carried by the double-layer stent, and can be widely applied to preparation of products for bone regeneration, inhibition of fibroblast migration, drug sustained-release carriers, bone tissue defect repair, antisepsis and anti-inflammation; the method has wide application prospects in the aspects of treating periodontitis, maxillofacial defects and the like.

A patch system and method for musculoskeletal repair is provided, the patch system including a patch defining a patch thickness, the patch being fabricated in whole or in part from a composition including a citrate polymer and a bioceramic filler, the patch defining a porosity gradient across the patch thickness. The patch may be defined by multiple patch layers, e.g., multiple fibers, wherein a first fiber associated with a first patch layer is not aligned relative to a second fiber in a second, adjacent patch layer.

The present invention relates to a method for surface treatment of orthopedic implants based on femtosecond laser. The surface treatment method comprises the following steps: cleaning and drying the surface of the orthopedic implant substrate; performing femtosecond laser treatment on the surface of the orthopedic implant substrate to form regularly arranged microstructures on the substrate surface; wherein, the orthopedic implant substrate comprises a metal substrate, a bioceramic substrate and a polymer material substrate; the microstructures include one or more of grooves, dot matrices or grids; performing plasma spraying of a biological coating on the surface of the orthopedic implant substrate after femtosecond laser treatment to finally obtain a surface-modified orthopedic implant; wherein, the biological coating comprises a titanium coating and a hydroxyapatite coating. Compared with the prior art, the present invention significantly improves the bonding force between the plasma-sprayed biological coating and the orthopedic implant substrate, and broadens the types of applications of the orthopedic implant substrate.

The invention relates to the technical field of additive manufacturing of biomedical materials, in particular to calcium silicate-based bioactive ceramic slurry for photocuring 3D printing and a preparation method of the calcium silicate-based bioactive ceramic slurry. The slurry is prepared from the following raw materials in parts by mass: 50 to 70 parts of calcium silicate-based biological ceramic powder, 15 to 30 parts of active monomer, 8 to 15 parts of oligomer, 0.5 to 2.5 parts of photoinitiator, 1 to 3 parts of wetting dispersant and 0.5 to 2 parts of flatting agent. By selecting the calcium silicate-based ceramic powder with specific morphology and particle size distribution, the problems that the biological ceramic slurry is easy to settle, high in viscosity, high in curing layer brittleness and the like due to high density and high surface polarity are successfully solved. The prepared slurry has the characteristics of high biological activity, proper viscosity, good stability, high green body strength after curing, good printing precision and the like, is especially suitable for preparing a bone repair scaffold with a complex porous structure, and can obtain a ceramic component with good mechanical properties, controllable degradation rate and excellent biological activity after printing, cleaning and sintering.

The invention provides a biological ceramic lining for an artificial hip joint replacement operation, and belongs to the technical field of medical clinical and biological materials. Comprising a shaft rod, the outer side of the shaft rod is sleeved with a transmission sleeve rod, and the outer side of the transmission sleeve rod is sleeved with a limiting sleeve rod; and the fixing assembly is used for fixing the ceramic lining and assisting in press-fit installation of the ceramic lining, and the fixing assembly is connected with the transmission sleeve rod and the limiting sleeve rod. The ceramic lining is arranged, the titanium layer, the coarse titanium layer and the hydroxyapatite coating are sprayed on the acetabular surface of the ceramic lining step by step, finally, a sandwich structure is formed on the acetabular surface of the ceramic lining, the sandwich structure is directly in press fit with the acetabulum in the operation, osseointegration is achieved, an acetabular cup prosthesis does not need to be used any more, and the manufacturing cost is reduced. The problems that in the prior art, an acetabular cup and a ceramic lining are mistakenly assembled, deformation is caused when the metal acetabular cup is pressed and matched, and consequently the ceramic lining is broken, and the abnormal sound occurrence rate is increased are solved to a certain extent.

This invention provides a bioceramic liner for total hip replacement surgery, belonging to the fields of medical clinical and biomaterials technology. It includes a shaft with a transmission sleeve sleeved on its outer side, and a limiting sleeve sleeve sleeved on the outer side of the transmission sleeve sleeve; and a fixing component for fixing the ceramic liner and assisting in press-fitting the ceramic liner. The fixing component is connected to both the transmission sleeve sleeve and the limiting sleeve sleeve. This invention, by setting a ceramic liner and progressively spraying a titanium layer, a coarse titanium layer, and a hydroxyapatite coating onto the acetabular surface of the ceramic liner, ultimately forms a sandwich structure on the acetabular surface of the ceramic liner. During surgery, it directly presses against the acetabulum, achieving osseointegration. This eliminates the need for an acetabular cup prosthesis, to some extent solving the problems of incorrect assembly of the acetabular cup and ceramic liner caused by existing technologies, as well as deformation during press-fitting of the metal acetabular cup, which leads to increased incidence of ceramic liner breakage and abnormal noise.

This invention provides an alumina ceramic, its preparation method, and its applications. The alumina ceramic, by mass parts, comprises: an alumina self-stabilizing system and a zirconium oxide self-stabilizing system; the alumina self-stabilizing system comprises 70-90 parts alumina and 1-2 parts stearic acid, and the zirconium oxide self-stabilizing system comprises 10-30 parts yttrium-stabilized nano-zirconia, 1-2 parts stearic acid, and 1-2 parts polyvinyl alcohol; wherein the median particle size of the alumina is 0.1 μm-0.25 μm, and the median particle size of the yttrium-stabilized nano-zirconia is 10 nm-50 nm. Through rational formulation of the components, selecting alumina and yttrium-stabilized nano-zirconia of specific particle sizes, and combining them with other raw materials, the resulting alumina ceramic exhibits high density, hardness, and fracture toughness, making it particularly suitable for preparing medical devices, bioceramics, or semiconductor device packaging components.

The invention discloses a wrinkled-fruit-shaped biological ceramic particle-based composite material as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The preparation method comprises the following steps: mixing 5-15% by weight of biological ceramic particles and 85-95% by weight of microfiber gel, and homogenizing at a high speed to obtain the composite material. According to the wrinkled-fruit-shaped biological ceramic particle-based composite material provided by the invention, the biological ceramic particles and the microfiber gel are combined, so that the wrinkled-fruit-shaped biological ceramic particle-based composite material not only has good biocompatibility, but also can promote cell adhesion and tissue regeneration at the combination part of soft and hard tissues. The composite material is particularly suitable for repairing tendon injury and can effectively promote regeneration of tendons and tendon bone dead points.

A micro-magnetic invisible orthodontic appliance is provided. The micro-magnetic invisible orthodontic appliance includes a bottom brace (1), an outer periodontal brace (2) and an inner periodontal brace (3). The bottom brace (1), the outer periodontal brace (2) and the inner periodontal brace (3) together form a U-shaped brace. A tooth receiving groove is defined between the outer periodontal brace (2) and the inner periodontal brace (3). The bottom brace (1), the outer periodontal brace (2) and the inner periodontal brace (3) are made from one of a polymer composite material, biological ceramic, and an interpenetrating polymer network material, dispersed with permanent magnetic neodymium-iron-boron powder, by one-piece molding or three-dimensional printing.

A system and method for increasing total dissolved solids (TDS) concentration and pH of water is provided herein. The water is processed using a variety of filtration and purification methods, including carbon filtration, water softening, reverse osmosis, and electrodeionization. After filtration and purification, the water is pumped into a mineral infusion chamber, including a plurality of bioceramic components. At least one TDS sensor monitors the TDS concentration of the water stream, and a flow rate out of the mineral infusion chamber is controlled by a flow control valve based on sensor data produced by the at least one TDS sensor.

The utility model discloses a filling device convenient for shaping a biological ceramic repair material. The device comprises a filler handle part, a filling rod and a filler head part, the filling rod is movably arranged in the filler handle part to form a filler body; the filler head part is connected with the filler handle part through the connecting part; a containing groove and a shaping opening are formed in the filler head, the containing groove is used for adding materials such as I Root-BP and MTA, and the shaping opening is used for shaping and filling the materials.

This invention relates to the field of bioceramic materials technology, specifically to a porous interconnected zirconia bone repair scaffold material and its preparation method. This invention aims to address the problems of poor mechanical properties and fragile interconnected structures in existing scaffolds under high porosity. The core preparation process includes: using a dual-size microsphere template, pre-fusion via acetone vapor annealing to form a stable interconnected window prototype; subsequently, constructing a continuous pore wall body by vacuum impregnation with high-viscosity zirconia slurry; then, using low-viscosity nano-zirconia sol for secondary positioning and reinforcement of the interconnected necks; finally, introducing diluted bioactive glass sol to impart surface bioactivity, followed by temperature-controlled degreasing and sintering to obtain the final product. This method, through template pre-fusion and a zoned sequential process, synergistically optimizes the scaffold's pore connectivity, mechanical strength, and bioactivity, making it suitable for the repair of weight-bearing bone defects.

This invention relates to a grain boundary and surface-doped rare-earth zirconium-based ceramic material, its preparation method, and its applications. By employing a stepwise doping method, some dopant elements are located at the grain boundaries and surfaces of the rare-earth zirconium-based ceramic material. Adjusting the type and content of dopant elements at the grain boundaries and surfaces alters the sintering activity of the rare-earth zirconium-based ceramic material, thereby regulating the grain size, number, and characteristics of the grain boundaries, ultimately optimizing the material's electrical and mechanical properties. The doping method employed is simple, low-cost, and highly versatile, meeting the doping element requirements of various rare-earth zirconium-based ceramics and suitable for large-scale applications. The rare-earth zirconium-based ceramic material obtained using the technical solution of this invention can be used in various fields such as grinding media, fiber optic connectors, mobile phone backplanes, dental materials, bioceramics, thermal barrier coatings, oxygen or nitrogen-oxygen sensors, and solid oxide fuel cells.

Systems and methods for additive-manufactured biocompatible implants. Many embodiments are directed to 30-printed biocompatible resins for fabricating custom implants. In several embodiments, the biocompatible resin is based on a ratio of biocompatible polymers. The biocompatible resin, in accordance with various embodiments, incorporates an antibacterial and / or antimicrobial agent, In some embodiments, the biocompatible resin incorporates a bioceramic to mimic native tissue.

To provide a bioceramic that is suitable for artificial bone materials and exhibits superior bioabsorbability.SOLUTION: A bioceramic material comprises: a plurality of bioceramic particles; and a bonding phase that binds the plurality of bioceramic particles to each other, wherein the bonding phase contains Ca and P and is constituted by a matrix phase composed of a first phase and a second phase dispersed within the matrix phase, and a halo pattern is observed in an electron diffraction pattern.SELECTED DRAWING: Figure 1