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520 results about "Osseointegration" patented technology

Osseointegration (from Latin osseus "bony" and integrare "to make whole") is the direct structural and functional connection between living bone and the surface of a load-bearing artificial implant ("load-bearing" as defined by Albrektsson et al. in 1981). A more recent definition (by Schroeder et al.) defines osseointegration as "functional ankylosis (bone adherence)", where new bone is laid down directly on the implant surface and the implant exhibits mechanical stability ( i.e., resistance to destabilization by mechanical agitation or shear forces). Osseointegration has enhanced the science of medical bone and joint replacement techniques as well as dental implants and improving prosthetics for amputees.

A bioactive porous titanium alloy human cervical intervertebral fusion device and its preparation method

The invention provides a porous titanium alloy human cervical interbody fusion cage with bioactivity and a preparation method thereof. The method comprises the following steps: firstly, inputting model data into electron beam melting equipment according to a design requirement to prepare a porous titanium alloy human cervical interbody fusion cage; secondly, preparing gelatin microspheres; and immersing gelatin microsphere dry powder in an rhBMP-2 solution for gelatin coating modification, preparing a gelatin solution A in double distilled water, immersing the porous titanium alloy human cervical interbody fusion cage in the gelatin solution A, mixing the rhBMP-2 gelatin microspheres and absolute ethanol to obtain suspension B, and immersing the gelatin-coating-modified porous titanium alloy human cervical interbody fusion cage in the suspension B to prepare the porous titanium alloy human cervical interbody fusion cage internally containing an rhBMP-2 sustained-release system. The cervical interbody fusion cage prepared with the method has modulus of elasticity close to that of natural bone tissues, and the porous structure and the bioactivity factor sustained-release system inside the cervical interbody fusion cage can induce growth of new bone tissues, so that the binding problem of bone-material interfaces is solved. Therefore, the cervical interbody fusion cage has bettermechanical compatibility and bone integration capability than those of a compact material.
Owner:维度(西安)生物医疗科技有限公司

Bone restoration body with composite porous structure and preparation method thereof

A bone restoration body with a composite porous structure and a preparation method of the bone restoration body. The bone restoration body comprises a porous metal bracket and an infill body with a porous structure, wherein the porous metal bracket is of a three-dimensional net structure, a plurality of pores are arranged in the inner part of the porous metal bracket, and the infill body with the porous structure is fully filled in all the pores. The preparation method combines the direct metal rapid prototyping technology and the freeze drying technology and comprises the steps of preparing the porous metal bracket by a structural design and the direct metal rapid prototyping technology, pouring uniformly-mixed polymer solution or polymer / biological ceramics mixing solution into the porous metal bracket, carrying out freezing treatment, and then forming the infill body with the porous structure through freeze drying so as to obtain the bone restoration body with the composite porous structure, wherein the infill body with the porous structure has micropore characteristics. The bone restoration body has good mechanics compatibility, can obtain good bone conduction performance and bone induction performance, improves bone integration efficiency and can be used for clinical treatment of segmental bone defect of a bearing part.
Owner:SHANGHAI JIAO TONG UNIV
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