65 results about "Fluorapatite" patented technology

The present invention provides a porous bioceramics for bone scaffold. The porous bioceramics according to the present invention comprises a biocompatible porous ceramic substrate having the property to thermal-decompose hydroxyapatite in contact with it; a fluorapatite (FA) inner layer formed on said porous ceramic substrate; and a hydroxyapatite (HA) outer layer formed on said fluorapatite inner layer. The insertion of FA intermediate layer can prevent the thermal reaction between ZrO2 and HA. Therefore, the present invention can provide the implant material into human body having excellent mechanical properties of zirconia as well as the biocompatibility, bioaffinity and bioactivity of HA. The present invention can also provide the implant material to promote osteoconduction and osteointegration in human body.

The present invention provides a porous bioceramics for bone scaffold. The porous bioceramics according to the present invention comprises a biocompatible porous ceramic substrate having the property to thermal-decompose hydroxyapatite in contact with it; a fluorapatite (FA) inner layer formed on said porous ceramic substrate; and a hydroxyapatite (HA) outer layer formed on said fluorapatite inner layer. The insertion of FA intermediate layer can prevent the thermal reaction between ZrO2 and HA. Therefore, the present invention can provide the implant material into human body having excellent mechanical properties of zirconia as well as the biocompatibility, bioaffinity and bioactivity of HA. The present invention can also provide the implant material to promote osteoconduction and osteointegration in human body.

A method for producing an implant whose surface is roughened by the sandblast method using shot material containing fluoroapatite. Fluoroapatite, compared to hydroxyapatite, has poor biocompatibility, but is superior in hardness. It also has a property of being dissolved in acid. As a result, by the sandblast method using shot material containing fluoroapatite, the surface roughening is performed quite effectively, and shot materials remained on the surface can easily be removed by acid.

The invention belongs to the field of molecular imaging technologies, and discloses a pH (potential of hydrogen)-responsive type ultra-sensitive nanometer fluorescent probe and a method for preparingthe same. The pH-responsive type ultra-sensitive nanometer fluorescent probe comprises pH-responsive matrix materials and fluorescent organic small-molecule dye. The pH-responsive matrix materials comprise calcium phosphate, hydroxy calcium phosphate, fluorapatite, calcium carbonate and ZIF series; the fluorescent organic small-molecule dye is positively charged dye or negatively charged dye. Themethod includes coating the positively charged dye with the negatively charged matrix materials; coating the negatively charged dye with the negatively charged matrix materials; coating the negativelycharged dye with the positively charged matrix materials. The pH-responsive type ultra-sensitive nanometer fluorescent probe and the method have the advantages that the fluorescent imaging sensitivity and specificity can be greatly improved as compared with the traditional small-molecule fluorescent dye, and response of tumor micro-environments can be detected in an ultra-sensitive manner; the pH-responsive type ultra-sensitive nanometer fluorescent probe which is a specific responsive probe prepared for unique properties of the tumor micro-environments is high in targeting, few in backgroundsignals and high in signal-to-noise ratio, small tumor can be detected in an ultra-sensitive manner, and the like.

The invention discloses an anticorrosive rubber material composed of the raw materials of, by weight, 0.2-0.6 parts of 8-10% sulfuric acid, 26-30 parts of melamine, 5-8 parts of a 37% formaldehyde solution, 7-10 parts of urea, 6-10 parts of microcrystalline cellulose, 1-1.2 parts of isopropanol, 2-3 parts of sulfur, 3-4 parts of maleic anhydride, 210-230 parts of neoprene S40V, 4-6 parts of methylparaben, 0.6-1 parts of triterpenoid saponin, 2-4 parts of calcium propionate, 2-3 parts of sodium diacetate, 1-3 parts of N-methylpyrrolidone, 4-5 parts of nano-grade calcium phosphate, 0.8-1 part of sodium sorbate, 40-54 parts of fluorapatite, and 2-4 parts of an anti-aging agent RD. according to the invention, with the crosslinking effect of maleic anhydride, microcrystalline cellulose forms a closer network structure in melamine resin formed by melamine, urea and formaldehyde, such that resin viscosity and tensile deformation resistance are well improved, and certain reinforcement and tackification effects are performed in the rubber material. Rubber flexure cracking resistance, hot air aging resistance and stability are improved. With the added anticorrosive dispersion liquid, the anticorrosive property of the rubber product can be effectively improved, and the service life of the rubber material can be prolonged.

A method of producing a fluoroapatite is provided. The method comprises preparing a slurry containing a hydroxyapatite which has at least one hydroxyl group, preparing a hydrogen fluoride-containing solution containing a hydrogen fluoride, mixing the hydrogen fluoride-containing solution with the slurry to obtain a mixture to thereby adjust a pH of the mixture in the range of 2.5 to 5, and reacting the hydroxyapatite with the hydrogen fluoride in the mixture in a state that the pH of the mixture is adjusted within the above range to thereby obtain the fluoroapatite by substituting the at least one hydroxyl group of the hydroxyapatite with fluorine atom of the hydrogen fluoride. The method can produce the fluoroapatite having improved acid resistance by reducing an impurity, such as ammonia, derived from a raw material to a low or very low level. Further, a fluoroapatite having high acid resistance is also provided. Furthermore, an adsorption apparatus using such a fluoroapatite is provided.

The present invention provides a highly-sintered fluorapatite glass-ceramic comprising a high Ca / Al or Sr / Al mole-ratio, that possesses a microstructure that induces apatite / bone deposition.