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1896 results about "Hydroxyapatites" patented technology

A group of compounds with the general formula M10(PO4)6(OH)2, where M is barium, strontium, or calcium. The compounds are the principal mineral in phosphorite deposits, biological tissue, human bones, and teeth. They are also used as an anticaking agent and polymer catalysts. (Grant & Hackh's Chemical Dictionary, 5th ed)

Osseointegrative surgical implant

Embodiments of the present invention provide an osseointegrative implant and related tools, components and fabrication techniques for surgical bone fixation and dental restoration purposes. In one embodiment an all-ceramic single-stage threaded or press-fit implant is provided having finely detailed surface features formed by ceramic injection molding and/or spark plasma sintering of a powder compact or green body comprising finely powdered zirconia. In another embodiment a two-stage threaded implant is provided having an exterior shell or body formed substantially entirely of ceramic and/or CNT-reinforced ceramic composite material. The implant may include one or more frictionally anisotropic bone-engaging surfaces. In another embodiment a densely sintered ceramic implant is provided wherein, prior to sintering, the porous debound green body is exposed to ions and/or particles of silver, gold, titanium, zirconia, YSZ, α-tricalcium phosphate, hydroxyapatite, carbon, carbon nanotubes, and/or other particles which remain lodged in the implant surface after sintering. Optionally, at least the supragingival portions of an all-ceramic implant are configured to have high translucence in the visible light range. Optionally, at least the bone-engaging portions of an all-ceramic implant are coated with a fused layer of titanium oxide.

Method of preparing a poorly crystalline calcium phosphate and methods of its use

InactiveUS7517539B1Readily injectableHigh strengthBiocideSurgical adhesivesOsteoporotic boneIntervertebral spaces
The present invention provides a novel process for producing a calcium phosphate cement or filler which hardens in a temperature dependent fashion in association with an endothermic reaction. In the reaction a limited amount of water is mixed with dry calcium phosphate precursors to produce a hydrated precursor paste. Hardening of the paste occurs rapidly at body temperature and is accompanied by the conversion of one or more of the reactants to poorly crystalline apatitic calcium phosphate. The hardened cements, fillers, growth matrices, orthopedic and delivery devices of the invention are rapidly resorbable and stimulate hard tissue growth and healing. A composite material is provided including a strongly bioresorbable, poorly crystalline apatitic calcium phosphate composite and a supplementary material. The supplementary material is in intimate contact with the hydroxyapatite material in an amount effective to impart a selected characteristic to the composite. The supplemental material may be biocompatible, bioresorbable or non-resorbable. A method for treating a bone defect also is provided by identifying a bone site suitable for receiving an implant, and introducing a strongly resorbable, poorly crystalline apatitic calcium phosphate at the implant site, whereby bone is formed at the implant site. The implant site may be a variety of sites, such as a tooth socket, non-union bone, bone prosthesis, an osteoporotic bone, an intervertebral space, an alveolar ridge or a bone fracture.

Edible compositions capable of removing oral biofilm

InactiveUS20050058744A1Significantly adsorbing oral bacteriaReduce bacterial adhesionCosmetic preparationsToilet preparationsDiseaseCarrageenan
An edible and/or chewable article of manufacture containing at least one food grade substance having adsorption affinity towards at least one dental plaque (biofilm) constituent and capable of reducing and/or removing the oral biofilm while present in the mouth. Particular articles of manufacture are chewing gums, sweets, candies, candy, and other nutritional bars, ice creams, chocolates, confectionery and bakery/pastry products, honey, dairy products and beverages, and oral hygiene products such as tooth pastes, oral gels and mouthwashes. A chewing gum having a conventional gum base and at least one food grade active substance having adsorption affinity towards at least one dental plaque (biofilm) constituent (bacteria and proteins and bacterial cell-free enzymes) and capable of reducing and/or removing the oral biofilm while present in the mouth. Active substances include polysaccharides and non-toxic salts thereof, such as alginates, chitosan, carboxymethylcellulose, agar and carrageenan, inorganic substances such as silica, hydroxyapatite and calcium carbonate and proteins, particularly gelatin and lectin. The article of manufacture removes and/or for prevents or reduces dental plaque (biofilm), and controlling oral, dental and periodontal diseases.

Method for preparing high-strength double-network hydrogel stent by virtue of 3D printing

The invention discloses a method for preparing a high-strength double-network hydrogel stent by virtue of 3D printing. The method comprises the following steps of adding a polymer monomer N, N-dimethyl acrylamide, an initiator, a crosslinking agent and sodium alginate (SA) into deionized water to form a solution and adding inorganic powder hydroxyapatite to obtain a sol; controlling and extruding the sol by a robot dispenser, and carrying out 3D printing molding to obtain a sol stent; placing the sol stent under ultraviolet light so that the monomer in the stent is subjected to photopolymerization and chemical cross-linking reaction to form a layer of chemically cross-linked network pre-molded hydrogel stent; immersing the pre-molded hydrogel stent into a CaCl2 aqueous solution so that SA in the stent is subjected to physical crosslinking to form a second layer of physically cross-linked network so as to obtain the hydrogel stent having physically and chemically cross-linked double-network. The hydrogel stent prepared by the method has higher mechanical strength and fine internal structure, and the three-dimensional morphology of the stent can be conveniently regulated and controlled to adapt to the complex application requirements of tissue engineering materials.

Multifunctional photocatalysis composite ceramic separation membrane as well as preparation method and use thereof

The invention belongs to the technical field of membrane and relates to a photocatalytic composite ceramic separation membrane using porous ceramic membrane as a carrier, a method for preparing the same and application of the separation membrane. The method is characterized in that a porous ceramic membrane substrate is used as the carrier to prepare hydroxyapatite sol and argent-titania composite sol through sol-gel technology; and a carrier membrane is subjected to secondary sol-gel dipping, drying and roasting sequentially to obtain the argent-carried titania/hydroxyapatite photocatalytic composite ceramic separation membrane with aperture of between 100 and 1,900 nm and porosity of between 20 and 55 percent. The photocatalytic composite ceramic separation membrane has biological adsorption and high photocatalytic activity and membrane permeability, improves separation of the composite membrane, photocatalytic degradation and sterilization, has remarkable effects of decontamination and sterilization, reduces the loss of porosity in the process of membrane preparation, has a simple preparation and application process, is easy for large-scale industrial production, integrates three units of membrane separation, photocatalytic degradation and sterilization and reduces investment and occupied area.

Artificial articular cartilage material and preparation method thereof

The invention discloses an artificial articular cartilage material, which relates to the field of chemical modification of hydrogel soft materials. Polyacrylamide-sodium alginate hydrogel is modified with graphene oxide and hydroxyapatite, and PAM-ALG-GO-HA composite hydrogel is prepared by a free radical polymerization reaction. The preparation method comprises the following steps: gradually adding needle-like nano HA particles into a GO solution which is uniformly dispersed in advance to form a mixed aqueous solution, adding an acrylamide monomer, an ALG monomer and related reactants for synthesizing PAM-ALG hydrogel, and performing the free radical polymerization reaction to prepare the PAM-ALG-GO-HA composite hydrogel. According to the artificial articular cartilage material disclosed by the invention, chemical modification is performed on the PAM-ALG hydrogel by fully using the two-dimensional structure of a GO nano chip and the functional groups on the surface and the excellent biological activity of HA, the mechanical property and biological activity of the PAM-ALG hydrogel are effectively improved, the application range of the PAM-ALG hydrogel is expanded, and the artificial articular cartilage material has clear scientific significance and a huge application value.
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