456 results about "Hydroxyapatites" patented technology

The invention discloses a preparation method of a metal doped type hydroxyapatite nanoflower. The method specifically comprises the following steps: dispersing a calcium source and soluble metal salt into water, adding acid phosphate, urea and L-histidine, uniformly mixing, carrying out a hydrothermal reaction, mechanically stirring, filtering, washing, and drying a hydrothermal system precipitate to obtain the corresponding metal-doped hydroxyapatite nanoflower. Compared with the prior art, the metal-doped hydroxyapatite nanoflower prepared by the preparation method disclosed by the invention is directly assembled by nanosheets, and a single metal type can be doped in a customized manner. According to the method, water is used as a unique solvent, the use of an organic solvent is avoided, the pH does not need to be adjusted in advance, the technological process is simple, operation is convenient, equipment investment is small, and the method is suitable for industrial production.

The invention relates to the technical field of marine ecological engineering, in particular to a marine coral reef ecological restoration method based on a foamed aluminum base material, which comprises the following steps: preparing a modified foamed aluminum main body structure, constructing a modified bioactive surface layer, filling a modified phase change material capsule, and putting a restoration unit. According to the invention, the foamed aluminum main body structure provides a stable three-dimensional through porous network, and a natural reef habitat environment is simulated; a hydroxyapatite coating or a polymer layer constructed on the surface of the coral bone-imitating material remarkably improves the coral larva attachment and colonization efficiency through coral bone-imitating inorganic components or specific polypeptides respectively; the phase-change material capsules filled inside buffer water temperature fluctuation through phase-change latent heat, a stable micro-thermal environment is provided for coral growth, the functions of all the components are complementary and synergistic, foamed aluminum provides a carrier for surface functionalization, the surface active layer optimizes a biological interface, the internal temperature adjusting unit guarantees ecological suitability, and an efficient repairing system is formed. The coral reef ecological restoration effect is obviously improved.

The invention relates to a starch pore-enlarging type high-chlorine-capacity long-acting high-temperature dechlorinating agent and a preparation method thereof, and belongs to the technical field of dechlorinating, the starch pore-enlarging type high-chlorine-capacity long-acting high-temperature dechlorinating agent comprises the following raw materials: complexing coating calcium hydroxide, modified hydroxyapatite, a composite inorganic adhesive, reinforcing and toughening whiskers, a composite pore-forming agent, a composite synergist, nano calcium carbonate and water; according to the starch reaming type high-chlorine-capacity long-acting high-temperature dechlorinating agent obtained by the invention, the breakthrough chlorine capacity is 40.9 to 44.9 percent, the crushing strength is 139 to 151N. Cm <-1 >, and the abrasion rate is 0.8 to 1.5 percent.

The invention discloses a graphene aerogel modified elastic graphite material and a preparation method thereof, and the graphene aerogel modified elastic graphite material comprises the following components by mass: 50-80 parts of crystalline flake graphite; 8 to 15 parts of graphene aerogel; 3 to 8 parts of aminated modified boron-doped carbon nanotubes; 2 to 6 parts of hydroxyapatite-cerium oxide composite nano particles; 1 to 4 parts of a polyimide-montmorillonite nano composite material; 0.5 to 3 parts of titanate coupling agent modified nano silicon dioxide; 1-3 parts of a dispersant; 2-5 parts of a binder; the amination modified boron-doped carbon nanotubes can enhance the electrical conductivity and interface bonding force of the material, the hydroxyapatite-cerium oxide composite nanoparticles improve the high-temperature stability and mechanical toughness of the material, and the polyimide-montmorillonite nanocomposite improves the corrosion resistance and resilience durability of the material. And the titanate coupling agent modified nano silicon dioxide further optimizes the dispersion uniformity of all the components, and the comprehensive performance of the material is remarkably improved.

A liner mat for waste pit management and drilling fluid recycling at well sites is described. The liner mat includes an adsorbent layer and a base layer. The adsorbent layer includes chitosan and polyhydroxyalkanoate (PHA). The base layer includes polylactic acid (PLA). In some cases, the base layer includes hydroxyapatite (HAp). The adsorbent layer contacts the drilling fluid. The adsorbent layer can mitigate microbial growth and adsorbs at least a portion of pollutants from the drilling fluid. The base layer provides structural support and resistance against mechanical stress and tearing.

The invention discloses a high-voltage-resistant brominated flame-retardant polyamide composition and a preparation method thereof, and belongs to the technical field of flame-retardant materials. The composition comprises the following components in percentage by mass: 30-80 wt% of aliphatic polyamide, 10-30 wt% of a brominated flame retardant, 0.5-10 wt% of an antimony-based synergist, 0.5-10 wt% of aromatic zinc carboxylate, 0.5-5 wt% of hydroxyapatite, 0.1-50 wt% of a reinforcing agent and 0-5 wt% of other auxiliaries, the sum of the contents of all the components is 100 wt%, and the raw material components are subjected to melt blending processing through a single-screw or double-screw extruder. The invention provides the high-voltage-resistant brominated flame-retardant polyamide composition, the relative tracking index (CTI) of the high-voltage-resistant brominated flame-retardant polyamide composition is greater than 400V, and the high-voltage-resistant brominated flame-retardant polyamide composition has high-level flame retardance and cost effect.

The invention relates to the field of high polymer material processing, and discloses a high-efficiency low-energy-consumption granulation process and system for a full-biodegradable multiphase composite material, and the process comprises the following steps: feeding raw materials such as polypropylene carbonate, polyester, plant fibers and four-stage activated biomass hydroxyapatite into a double-screw extruder with the length-diameter ratio of not less than 64: 1 in a grading manner according to heat sensitivity; the temperature, the pressure and the shear field are cooperatively controlled, and three-section type temperature distribution of intensified melting, short-time reaction and rapid cooling is established; and carrying out three-stage gradient vacuum devolatilization and underwater pelletizing to obtain a finished product. The four-stage activated biomass hydroxyapatite is prepared by plasma etching, hydrophobic coating, interface coupling and melt pre-dispersion. The problem of degradation of heat-sensitive components is solved through graded feeding and asymmetric temperature control, the dispersity and interface bonding force of the filler are improved by utilizing a four-stage activation technology, closed-loop control is realized by combining online rheology monitoring and an energy consumption model, and continuous production of the full-biodegradable material with low energy consumption, low volatile matter and high mechanical property is realized.

The invention provides methyl vinyl silicone rubber. The methyl vinyl silicone rubber is prepared from the following raw materials in parts by weight: 85 to 95 parts of methyl vinyl silicone rubber raw rubber, 27 to 35 parts of modified filler, 0.3 to 1.5 parts of vulcanizing agent, 0.5 to 1.5 parts of assistant crosslinking agent and 0.2 to 0.8 part of bulking agent, the modified filler is prepared from the following raw materials: chitosan, a filler and methacrylic acid, and the dosage ratio of the chitosan to the filler to the methacrylic acid is (25-35) g: 22g: (0.07-0.15) mol; the filler comprises hydroxyapatite and silicon dioxide. The invention also provides a preparation method of the methyl vinyl silicone rubber. The methyl vinyl silicone rubber provided by the invention has excellent tensile strength and damp-heat aging resistance.

The invention provides a composite sun-screening agent based on an encapsulation technology as well as a preparation method and application of the composite sun-screening agent. The preparation method of the composite sun-screening agent comprises the following steps: fully dispersing hydroxyapatite nanoparticles in an alkaline solvent, adding a dopamine monomer, and carrying out oxidative polymerization reaction, centrifugal washing and drying to obtain HAP-PDA composite nanoparticles; and fully dispersing the HAP-PDA composite nanoparticles in a solvent, adding a mixed solution of a chemical sun-screening agent and an antioxidant and a surfactant, and performing encapsulation reaction and centrifugation to obtain the product. According to the invention, a polydopamine and hydroxyapatite composite encapsulation technology is innovatively adopted, so that the stability and biocompatibility of the sun-screening agent and the antioxidant are remarkably improved, the sun-screening effect is enhanced, and the product is endowed with a lasting sun-screening effect and excellent oxidation resistance. According to the invention, the limitation of a traditional sunscreen product is broken through, and safer, more efficient and more comfortable sunscreen experience can be provided for consumers.

The application discloses a pH-responsive degradable composite bacteriostatic film derived from waste bone powder extract and a preparation method thereof. The main components of the film are collagen and hydroxyapatite extracted from waste bone powder, citric acid monohydrate-betaine and lactic acid-betaine eutectic solvent, and in addition, purple corn anthocyanin is used as a pH response agent, and citric acid monohydrate-betaine eutectic solvent is used as a crosslinking agent and a bacteriostatic agent. In the preparation process, collagen and hydroxyapatite are mixed with an aqueous solution of eutectic solvent and heated, and after the system is reduced to room temperature, the anthocyanin aqueous solution is added, mixed, and ultrasonic defoaming is performed, then the film forming liquid is poured into a clean mold, vacuum dried, and cooled to remove the film. The pH-responsive degradable composite film prepared based on the above method has good properties, not only has the characteristics that the overall color changes with the microenvironment pH, but also has good mechanical strength, bacteriostasis and degradability, and has wide application potential in many fields such as food preservation.

The invention discloses a hydrogenated butadiene-acrylonitrile rubber composite material for cryogenic heat preservation and a preparation method thereof in the field of polymer composite materials, and the composite material is characterized in that zirconium-silicon composite modified hydroxyapatite and boron-nitrogen co-doped mesoporous alumina are introduced, so that the mechanical property and heat preservation effect of the material in a low-temperature environment are remarkably improved. The zirconium-silicon oxide network is constructed on the surface of hydroxyapatite by adopting a sol-gel method, and the doped mesoporous structure with the high specific surface area is obtained by adopting alkoxide as a precursor through hydrothermal treatment and calcination. When the rubber is mixed, the functional filler is dispersed at a high temperature, and then the plasticizer is added to ensure uniform distribution of the filler. The obtained composite material has excellent tensile strength, elongation at break and low heat conductivity coefficient at the liquid nitrogen temperature, and is suitable for the cryogenic thermal insulation fields of hydrogen energy storage and transportation, aerospace sealing and the like. All the raw materials are commercially available chemicals, the process is controllable, and industrial production is easy.

The invention discloses a method for preparing a multifunctional nano-hydroxyapatite-based tumor vaccine by a one-step method, and relates to a preparation method of a nano-hydroxyapatite-based tumor vaccine. The invention aims to solve the problems of low antigen presentation efficiency of existing tumor vaccines and complex preparation process of nano vaccines based on tumor cell membranes. The preparation method comprises the following steps: 1, preparing small-particle-size calcium-based nanoparticles; and 2, synthesizing the HAP NV (at) DOX nano compound. The preparation method is used for preparing the multifunctional nano-hydroxyapatite-based tumor vaccine by a one-step method.

The invention provides nanoscale hydroxyapatite as well as a preparation method and application thereof, and relates to the technical field of hydroxyapatite. The preparation method provided by the invention comprises the following steps: completely reacting calcium hydroxide slurry with a phosphoric acid solution under mechanical mixing, and standing and curing to obtain hydroxyapatite slurry; mixing the hydroxyapatite slurry with a binder, and calcining at 800-1200 DEG C to obtain a precursor; and grinding the precursor in a water phase to obtain a nano suspension, and carrying out spray drying to obtain the nano-scale hydroxyapatite. According to the preparation method disclosed by the invention, a stable multi-stage pore structure can be constructed through high-temperature calcination, and the regularity and the stability of the size of the hydroxyapatite can be improved through spray drying treatment, so that the nano-scale hydroxyapatite has high biological activity and stability, and the defect that pure hydroxyapatite slurry is not resistant to scouring is effectively overcome.

This invention relates to the field of biomedical technology, specifically to a biomimetic piezoelectric scaffold for promoting bone repair, its preparation method, and its applications. The biomimetic piezoelectric scaffold provided by this invention is produced by electrospinning PLLA into oriented nanofibers, and then modifying the fiber surface with nano-hydroxyapatite. To enhance the adhesion of hydroxyapatite to the fiber surface, a polydopamine layer is modified between the two as a connecting layer, ultimately resulting in a biomimetic piezoelectric scaffold with high porosity, good osteointegration, and osteogenic promoting effects. This scaffold exhibits good bone regeneration promoting effects in in vitro MSC recruitment, osteogenic differentiation experiments, and repair of skull bone defects in rats.

The invention discloses a polyamide composite material, a preparation method thereof and a connector. The polyamide composite material comprises the following components in parts by weight: 25-65 parts of polyamide resin, 25-55 parts of polyphenyl ether resin, 3-15 parts of an organic phosphorus halogen-free flame retardant and 0.3-4 parts of a stabilizer. The stabilizer is prepared from hydroxyapatite and wollastonite; the polyamide resin comprises aliphatic polyamide resin and semi-aromatic polyamide resin. The polyamide composite material disclosed by the invention has high insulation and pressure resistance in a high-salt-concentration application environment.

The invention discloses a method and system for treating neutral high-calcium wastewater through combination of an MICP technology and chemical precipitation, and relates to the technical field of wastewater treatment. The method comprises the following steps: S1, inoculating a bacterial liquid containing synechocystis into neutral high-calcium wastewater; s2, under the daytime illumination condition, calcium ions in the wastewater are induced to form calcium carbonate precipitates through photosynthesis of synechocystis, and primary calcium removal is carried out; s3, under the dark condition at night, phosphate is added in batches by means of extracellular polymeric substances secreted by synechocystis, residual calcium ions in the wastewater are induced to form calcium phosphate or hydroxyapatite precipitates, and deep calcium removal is carried out. The day and night alternate metabolism characteristic of synechocystis is applied to neutral high-calcium wastewater treatment, so that efficient decalcification under a neutral condition can be realized, and stable water quality and controllable precipitation are considered. The open pond type reactor is adopted, so that water can stand and settle, mechanical stirring or temperature control equipment is not needed, and the operation cost is reduced.

This invention provides a photocatalytic composite nanoenzyme self-cleaning coating, its preparation method, and its application. Specifically, it includes: preparing solution A with Ca(NO3)2·4H2O and nano-cerium oxide; preparing solution B with (NH4)2HPO4 and hexadecyltrimethylammonium bromide; mixing solutions A and B, and reacting at high temperature to obtain cerium oxide nanoenzyme / hydroxyapatite microspheres; and using (NH4)6Mo7O... 24 Solution M is prepared by dissolving Fe(NO3)3·9H2O in deionized water; solution N is prepared by dissolving Fe(NO3)3·9H2O in deionized water; solutions M and N are mixed to obtain a precursor; the precursor is reacted with cobalt oxide at high temperature to obtain Co / Fe2(MoO4)3; tetraethyl orthosilicate, anhydrous ethanol, deionized water, and ammonia are mixed and sealed for aging; after adding a modifier, it is mixed with cerium oxide nanoenzyme / hydroxyapatite microspheres and Co / Fe2(MoO4)3, sprayed onto the obtained composite coating, and cured at high temperature to obtain a self-cleaning coating. This invention, by loading a photocatalyst and nanoenzyme / hydroxyapatite microspheres onto the surface of a modified SiO2 gel, effectively improves the photocatalytic activity and self-cleaning performance of the coating while maintaining good optical transmittance.

This invention provides a high-performance implantable biomedical product based on polylactic acid (PLA) and its preparation method. The preparation method, by weight, involves first melt-blending 10-20 parts of polybutylene adipate succinate (PSA) with 1-2 parts of hydroxyapatite to obtain a PBSA / HA mixture; then mixing 78-89 parts of PLA with PBSA / HA and extruding the mixture via a twin-screw extruder to obtain PLA / PBSA / HA granules; finally, using a micro-injection molding process to prepare the high-performance implantable biomedical product. This method induces a strong shear field through micro-injection molding, enabling in-situ fiber formation of the PBSA dispersed phase within the PLA matrix. Simultaneously, the addition of a specific amount of hydroxyapatite significantly enhances the product's toughness, resulting in a product with excellent biocompatibility and osteoinductive activity.

This invention discloses a method for reducing the stability of amorphous calcium phosphate. The method involves adding an additive solution to an ACP solution; the additive is a calcium- and phosphorus-free inorganic salt that does not react with calcium ions and orthophosphate ions to form a precipitation reaction. This invention, by adding an inorganic salt after the formation of amorphous calcium phosphate, primarily increases the ionic strength of the solution, reduces calcium and phosphorus activity, promotes the dissolution of amorphous calcium phosphate, thereby altering its structure, significantly reducing its stability, and accelerating the formation of hydroxyapatite. Furthermore, this method uses low-cost raw materials, contributing to cost reduction.

The invention discloses biomimetic mineralized porous aerogel as well as a preparation method and application thereof, and belongs to the technical field of natural polymer-based composite materials. The preparation method comprises the following steps: dissolving sodium alginate powder in a weakly alkaline aqueous solution containing phosphate to obtain a uniformly dispersed precursor solution; freezing treatment is performed to form frozen gel with an ice crystal template structure; immersing the frozen gel into a solution containing calcium ions, and synchronously realizing crosslinking of a sodium alginate network and in-situ mineralization of hydroxyapatite at low temperature to obtain mineralized composite gel; finally, the mineralized composite gel is subjected to solvent replacement and normal-pressure drying treatment, and the biomimetic mineralized aerogel is prepared. According to the method, ionic crosslinking and in-situ mineralization are synergistically realized through a one-step method, the process is simple and efficient, expensive equipment is not needed, and the cost is low. The prepared aerogel has a rich pore structure, a high specific surface area and good biological activity, and has a wide application prospect in the fields of environmental adsorption materials, biological scaffold materials and the like.

The present application relates to the technical field of biomedical materials, and discloses a biological activity and biocompatibility surface treatment method for dentures and implants, which comprises the following steps: a) performing surface pretreatment on the base body of the denture or implant; b) applying a composite coating containing hydroxyapatite particles and biocompatible resin adhesive on the surface of the pretreated base body; c) performing low-temperature thermal curing on the composite coating to form a composite coating layer; and d) performing precision polishing on the surface of the cured composite coating layer to selectively remove part of the resin adhesive on the surface. Through mechanical locking of the base body surface and chemical combination of the interface inside the coating, a composite coating layer which is firmly combined with the base body and chemically stable is obtained; meanwhile, through low-temperature curing and surface activation treatment, the hydroxyapatite is exposed on the surface of the coating layer while the biological activity of the hydroxyapatite is retained, so that the coating layer is endowed with effective biological functions.

This application relates to the field of biological control, specifically disclosing a compound bacterial agent containing Bacillus thuringiensis, its preparation method, and its application. A method involves fermenting Bacillus thuringiensis HP-SYJ2 to a concentration of (3-8) × 10⁻⁶. 9 A Bacillus thuringiensis HP-SYJ2 bacterial suspension was obtained by mixing cfu / ml with hydroxyapatite and biochar, then mixing the mixture with the Bacillus thuringiensis HP-SYJ2 bacterial suspension, soaking, and air-drying until the moisture content is 30-40%, followed by maturation for 1-2 weeks to obtain the loading material. Fenugreek seed oil, emulsifier, soil penetrant, and water were mixed and sheared to obtain an emulsion with a fenugreek seed oil concentration of 0.1-0.5 wt%. The loading material and emulsion were packaged separately and mixed before application. This compound microbial agent can be used for the prevention and treatment of root rot in medicinal herbs or to promote their growth. It has the advantages of both preventing and treating root rot in medicinal herbs and promoting their growth.

The invention provides a process of purification of antibody or fusion protein from protein mixture comprising product and process related impurities. The process provides the use of hydroxyapatite chromatography for the separation of low molecular weight impurities and basic variants. In addition, invention further provides a scalable purification process to remove product and process related impurities.

The invention provides a mussel bionic composite adhesive and a preparation method thereof, and belongs to the technical field of high-performance adhesives. The composite material is prepared from 88 parts by mass of premixed mother liquor, 3-6 parts by mass of a silane coupling agent KH-560 and 4-8 parts by mass of nano-hydroxyapatite, 3, 4-dihydroxy phenyl methacrylamide is taken as an adhesion function core of the premixed mother liquor, is cooperated with 2-ethylhexyl acrylate and isobornyl methacrylate, and is compounded with a specific composite photoinitiator, an antioxidant 1010 and an ultraviolet absorbent 328. The preparation method comprises the following steps: preparing premixed mother liquor under the dark condition of 30 DEG C, primarily dispersing the premixed mother liquor, the silane coupling agent and the nano-hydroxyapatite under normal pressure, and performing vacuum stirring, dispersing and degassing under-0.05 to-0.08 MPa. The adhesive has excellent adhesion to inorganic base materials such as hydroxyapatite and natural stone, has compressive strength of more than or equal to 22MPa and high elongation at break of 35-55%, has outstanding weather resistance and stable performance after long-term ultraviolet aging, and is suitable for the fields of medical bone repair material fixation, stone adhesion, high-end composite material forming and the like.

The invention discloses a gradient degradation type personalized absorbable sternum fracture fixing plate and a preparation process, and belongs to the technical field of medical implant materials. Comprising an anatomical adaptive plate body and an integrated locking assembly, the plate body is of a partitioned structure of a middle supporting area and an edge buffering area, a gradient pore array penetrating through the thickness direction is formed in the surface of the plate body, and a hydroxyapatite-collagen composite coating is loaded on the inner wall of a pore; the plate body is made of a composite absorbable material through 3D printing forming and hot pressing post-treatment, and the composite absorbable material comprises, by weight, 60%-70% of polylactic acid-glycolic acid copolymer (PLGA, LA / GA = 75 / 25), 15%-20% of silanized magnesium alloy microwires, 5%-10% of hydroxyapatite nano-particles and 5%-10% of polycaprolactone (PCL). Space-time matching of the degradation rate and the bone healing process is achieved through the partition gradient structure, the magnesium alloy microwires enhance the mechanical property and release active ions to promote osteogenesis, and the method has the advantages of personalized adaptation, gradient degradation, bone regeneration promotion and the like.

The invention discloses a mineralization repair type oral cavity and throat nursing material for middle-aged and elderly people and a preparation method thereof. The nursing material consists of a core mineralization precursor, a function relieving component and an auxiliary synergistic component, wherein the core mineralization precursor is a biocompatible mineralization matrix of modified hydroxyapatite loaded carbon nitride quantum dots, and is used for realizing mucous membrane mineralization repair; the functional soothing component is a mixture of dihydromyricetin, a licorice extract and a menthol-beta-cyclodextrin inclusion compound, and has mild soothing and anti-inflammatory effects; the auxiliary synergistic component is a mixture of bovine serum albumin and a gamma-polyglutamic acid-g-methoxypolyethylene glycol derivative, and a mineralized precursor is stabilized and mucous membrane adhesion is enhanced by constructing a protein nanocage structure. By optimizing the process, the production efficiency and stability are improved, the biological safety is enhanced, the nursing requirements of middle-aged and elderly oral cavity and throat sensitive mucous membranes are better met, and the oral cavity and throat sensitive mucous membrane repairing gel is suitable for oral cavity mucous membrane sensitive repairing and chronic pharyngitis auxiliary nursing.

This application relates to the field of wastewater treatment, specifically disclosing a sulfur autotrophic denitrification process; including the following specific steps: S1: After adjusting the pH of calcium nitrate tetrahydrate solution and ammonium dihydrogen phosphate solution to alkaline, triethanolamine is added dropwise to the calcium nitrate solution, followed by the addition of ammonium dihydrogen phosphate solution to form a reaction solution. The pH of the reaction solution is maintained at alkaline, and the reaction is heated. After filtration, washing, and drying, hydroxyapatite powder is obtained. The hydroxyapatite powder is mixed with a foaming agent, foam stabilizer, and adhesive, pressed into shape, and sintered to obtain a porous ceramic carrier; S2: The porous ceramic carrier, ground inorganic energy material, and denitrifying bacteria are added to the wastewater to be treated, mixed, and subjected to aeration treatment. The inorganic energy material is replenished periodically to complete the process. The sulfur autotrophic denitrification process used in this application has high denitrification efficiency, and no replenishment of denitrifying bacteria is required during the process.

To provide a composition containing a novel ingredient that can bring about at least an acceptable level of sebum control in keratinous substances such as skin. [Solution] The present invention relates to a composition comprising (a) (i) at least one inorganic oxide, preferably a metal oxide, more preferably an alkaline earth metal oxide, and (ii) at least one fatty acid or a salt thereof, preferably a saturated fatty acid or a salt thereof, more preferably a metal salt of a saturated fatty acid, and (b) at least one second powder selected from particles containing silica and hydroxyapatite. The composition according to the present invention can provide at least an acceptable level of sebum control to keratinous substances such as skin.

Antibody compositions and methods for the purification of antibodies are provided. Purification methods provided involve the use of hydroxyapatite resin (HA) to separate an antibody of interest from one or more impurities.

The present disclosure provides a device manufacturing process comprising designing a mold for stereolithography resin printing, wherein the mold is configured to minimize distortion from pyrolysis and sintering, printing the mold from resin using stereolithography, pyrolyzing the mold to convert resin into carbon structure, filling the carbon structure with ceramic slurry, drying the ceramic slurry within the carbon structure, and thermally processing the carbon structure and ceramic slurry to decompose the carbon structure and sinter the ceramic slurry into consolidated ceramic part. The ceramic slurry may comprise hydroxyapatite or yttria-stabilized zirconia particles. The mold design may limit beam thickness and wall thickness to 0.6mm and account for isotropic shrinkage of approximately 50% during pyrolysis. Thermal processing may involve sintering at 1200°C for hydroxyapatite or 1450°C for yttria-stabilized zirconia to produce ceramic scaffolds with sub-millimetric channels and intricate lattice structures for biomedical applications.