844 results about "Calcium biphosphate" patented technology

The invention discloses ultra-high performance concrete and a preparation method thereof. The ultra-high performance concrete comprises the following components in percentage by mass: 15%-25% of cement, 3%-6% of nano SiO2, 30%-35% of fly ash or steel slag powder, 35%-40% of recycled aggregate, 1%-4% of fiber, 0.5% of a microbial remediation agent and 1%-3% of nano TiO2. The preparation method comprises the following steps: S1, pretreating the recycled aggregate; and S2, packaging the microbial remediation agent: mixing the bacillus pasteurii spores with calcium lactate, and wrapping the mixture in calcium phosphate microspheres. S3, step-by-step stirring; S3.1, dry mixing: uniformly stirring the cement, the fly ash, the nano SiO2, the nano TiO2 and the recycled aggregate; s3.2, wet mixing is carried out, water solution fibers containing the polycarboxylic acid water reducing agent are added, uniform stirring is carried out, and the water-binder ratio of the water solution containing the polycarboxylic acid water reducing agent is 0.18; s3.3, final mixing: adding the packaged microbial remediation agent, and uniformly stirring; and S4, directional curing: performing steam curing at 80 DEG C for 48 hours, performing ultraviolet irradiation, and performing constant-temperature and constant-humidity curing for 7 days. The ultra-high performance concrete has the effects of low cost, low carbon emission, multi-function integration and repeatable crack self-repairing.

The invention relates to a silk fibroin biological material with high beta-fold content and a preparation method thereof, and belongs to the technical field of biological extraction. The method comprises the following steps: preparing a regenerated silk fibroin solution; adding an enzyme catalytic promoter and an enzyme into the regenerated silk fibroin solution for incubation; the enzyme catalysis auxiliary agent is selected from one or more of a metal ion catalyst, a zwitterionic surfactant, a functionalized ionic liquid and a calcium phosphate nano-cluster; and centrifuging, cleaning and drying the obtained product to obtain the silk fibroin biological material with high beta-fold content. The silk fibroin material has higher beta-folding amount through primary structure modification, the space structure is more crystallized, and the amino acid sequence is more regular and ordered. The silk fibroin material provided by the invention has excellent mechanical properties, efficiency and yield, and is a biological protein material with great development potential.

The invention relates to the technical field of sludge reduction and resource utilization, in particular to a method for resource utilization of sludge gasification slag. According to the method, municipal sludge gasification slag is smashed and then subjected to acid leaching, acid leaching liquid and acid leaching slag are obtained, iron in the acid leaching liquid is recycled, meanwhile, the acid leaching slag is subjected to alkaline leaching, under the strong alkaline condition, a calcium source is added into alkaline leaching liquid, then calcium phosphate sediment can be obtained, and iron in alkaline leaching separation liquid is recycled; a calcium ion solution can be generated in the processes of recovering iron in the pickle liquor and refining calcium phosphate, and the obtained calcium ion solution can be used as a calcium source for comprehensive utilization. The method disclosed by the invention can be used for realizing extraction and resource utilization of phosphorus, iron, aluminum and calcium in the sludge gasification slag, and has important significance on environmental protection and resource saving.

To provide a medical tissue reconstruction material, which is involved in tissue reconstruction and exhibits superior tissue affinity, tissue conductivity, and mechanical properties, and a method for producing the same.SOLUTION: The present invention provides a composite comprising a biodegradable polymer and calcium phosphate exhibiting one of scaly, acicular, grooved, or linear recessed structures, and / or calcium carbonate containing vaterite, the composite meeting specific conditions.SELECTED DRAWING: Figure 3

The invention discloses a compound feed for raising plateau live pigs and a preparation method thereof, and relates to the technical field of feed processing. The compound feed for raising the plateau live pigs is prepared from manganese-selenium compound modified charcoal, soybean polysaccharide polylysine-based supported nanoparticles, aspergillus oryzae, soybean meal powder, corn flour, wheat bran, mountain flour, calcium hydrophosphate, table salt and multivitamins. Manganese-selenium composite modified charcoal, soybean polysaccharide polylysine-based supported nanoparticles and aspergillus oryzae are subjected to co-fermentation culture to form a uniform, stable, loose and porous three-dimensional network fermentation substrate composite system, so that the damage of gastric acid to components is reduced, the targeted release of intestinal tracts is realized, and the bioavailability is improved. The composite functional additive which is high in nutrition, easy to absorb, anti-oxidation, anti-anemia, anti-ultraviolet radiation and the like is obtained, and the adverse effects of low temperature, oxygen deficit and ultraviolet factors on animal growth and feed oxidative rancidity are effectively reduced.

The invention relates to a curcumin-loaded MMP response type melittin nano-pellicle vesicle as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The preparation method comprises the following steps: firstly, preparing curcumin entrapped lipidosome; then carrying out culture amplification on engineering bacteria carrying melittin recombinant plasmids, extracting cell membranes after removing cell walls, and carrying out ultrasonic treatment and membrane extrusion to obtain melittin cell membrane nano-vesicles; fusing the curcumin lipidosome and the cell membrane nano-vesicles in an ultrasonic extrusion mode to obtain fused vesicles; and finally, carrying out surface calcium phosphate mineralization treatment on the fused vesicles to obtain the curcumin-loaded MMP response type melittin nano pellicle vesicles. The nano mycofilm vesicle prepared by the invention can be used for preparing antitumor drugs, and the biocompatibility and in-vivo stability of nanoparticles are improved by introducing a calcium phosphate coating; through combined delivery of melittin and curcumin, the anti-tumor effect is enhanced, so that the growth and proliferation of tumor cells are inhibited.

The invention belongs to the field of feeds, and discloses a biological feed containing a microbial microcapsule preparation and a preparation method of the biological feed. The biological feed is prepared from the following components in parts by weight: 90 to 93 parts of wall-broken rhodopseudomonas palustris powder, 2 to 3 parts of lysine hydrochloride, 0.1 to 0.5 part of methionine, 0.1 to 0.5 part of threonine, 0.3 to 1 part of arginine, 2 to 3 parts of calcium hydrophosphate, 1 to 2 parts of calcium carbonate, 0.5 to 1.2 parts of an antioxidant additive, 0.3 to 0.8 part of modified nano montmorillonite and 1 to 5 parts of a microbial microcapsule preparation. According to the biological feed, the wall-broken rhodopseudomonas palustris serves as basic nutrition and a main microorganism source of the feed and is matched with the compound probiotics of the microorganism micro-capsule preparation, the intestinal nutrition utilization rate is effectively increased, meanwhile, the antioxidant additive is added, and the problems that a single additive is narrow in function and prone to oxidation are solved; the modified nano montmorillonite is added to solve the problem of antagonism of toxin adsorption and mineral absorption.

The invention discloses a high-strength artificial bone repair material and a preparation method thereof. According to the preparation method, collagen and calcium phosphate are taken as raw materials, and the artificial bone repair material is formed through the following step S100 or step S200. The step S100 comprises the following steps: mixing a collagen solution and calcium phosphate, adding a cross-linking agent to obtain collagen hydrogel, compressing to remove free water in the hydrogel so as to reduce the volume of the hydrogel, and freeze-drying for forming; the step S200 comprises the following steps: uniformly mixing collagen and calcium phosphate to prepare calcium phosphate collagen composite particles, weighing the collagen composite particles and calcium phosphate powder, adding the collagen composite particles and the calcium phosphate powder into a collagen solution, adding a cross-linking agent for cross-linking, and carrying out freeze-drying molding. The preparation method obviously enhances the mechanical strength of the artificial bone repair material on the premise of ensuring excellent degradation performance and biological activity.

The invention discloses a preparation method for simultaneously and efficiently extracting crocodile polypeptide and crocodile oil, and relates to the technical field of biological extraction, crocodile meat is used as a raw material, and heating micro-pressure treatment is sequentially performed to promote component dissolution; a multi-stage enzymolysis process is adopted, alkaline protease, neutral protease and lipase are sequentially used, and a calcium phosphate system is used for assisting filtration and a natural antioxidant is added in a gradient manner in the enzymolysis process; performing plate frame filtration and standing layering subsequently to realize crude separation of the oil peptide; finally, the crocodile polypeptide liquid is subjected to multi-stage membrane filtration and spray drying, the crocodile crude oil is subjected to ultrasonic-assisted fishy smell removal, ceramic membrane fine filtration and gradient cooling phase change refining, and after enzymolysis treatment and before filtration, a composite additive is added into enzymatic hydrolysate and stirred. No organic solvent exists in the whole process, and the product yield, purity and oxidation stability are remarkably improved.

The present invention relates to a method of manufacturing a surface-modified material wherein the method comprises the steps of applying a coating composition onto at least one surface of a substrate to form a porous coating thereon wherein the coating composition comprises mineral particles selected from the group consisting of calcium carbonate, calcium phosphate, hydromagnesite and mixtures thereof and a binder, and impregnating the porous coating with at least 150% by weight of an impregnating liquid composition based on the total weight of the porous coating to form a constraining liquid layer within and on the porous coating wherein the impregnating liquid composition is chemically inert to the substrate and the porous coating. Furthermore, the invention relates to a corresponding surface-modified material, an article comprising the same and the use of such a material.

The invention discloses a surface coating modified calcium phosphate microsphere and a preparation method thereof, and belongs to the technical field of calcium phosphate microsphere preparation. The surface coating modified calcium phosphate microspheres are prepared from the following components in parts by weight: 60 to 68 parts of calcium phosphate ceramic powder, 20 to 32 parts of modified bioactive bodies, 8 to 12 parts of composite pore forming agents and 2 to 5 parts of binding agents, the modified bioactive body is prepared from vinyltriethoxysilane, butyl dibutyl phosphate, citric acid, calcium acetate, magnesium sulfate and polyether-ether-ketone fibers, and the composite pore-forming agent is prepared from octyl dimethyl tertiary amine, epoxy chloropropane, hydrolyzed soybean protein and starch. The calcium phosphate microspheres prepared by the method have excellent porosity and biological activity.

The present application relates to the field of ceramsite, and specifically discloses a method for preparing binary ceramsite using coal gangue and the obtained ceramsite. The method comprises the following steps: preparing the core: fully mixing carbon-free industrial waste slag with calcium phosphate solution at a ratio of 1kg: (0.4-0.8)L, pressurizing, and then granulating to obtain green balls, and uniformly spraying a binding solution on the surface of the green balls to obtain the core; preparing the coating material: fully mixing coal gangue with sodium alginate solution at a ratio of 1kg: (0.2-0.5)L to obtain the coating material; overmolding: uniformly coating the core with the coating material to form a binary green ball, wherein 0.15 < d / D < 0.75, d is the green ball diameter, and D is the binary green ball diameter; preparing the ceramsite: drying, pyrolyzing, decarbonizing, sintering, and cooling the binary green balls to form binary ceramsite. The obtained ceramsite product not only has no black core, excellent strength, but also good water absorption.

The invention discloses a degradable organic-inorganic composite film and a preparation method and application thereof, and belongs to the technical field of composites.The method comprises the steps that 1, an organic amine stabilizer, a calcium source, a phosphorus source and an organic solvent are used for preparing a calcium phosphate nano-cluster precursor, and calcium phosphate nano-clusters are obtained through further separation; (2) mixing the calcium phosphate nano-cluster and a natural polymer material to prepare a uniformly dispersed emulsion, the natural polymer material including carboxymethyl chitosan and alginate, using the emulsion to prepare a membrane, and during the membrane preparation process, generating an evaporation-induced self-assembly process to prepare the membrane. The degradable organic-inorganic composite film is obtained by combining a rod-like hydroxyapatite nanocrystal which is formed by phase change of the calcium phosphate nanocluster and crystallization with a natural high polymer material. The organic-inorganic composite film has adjustable mechanical properties, can be naturally and directly degraded in soil, and has wide application prospects in the fields of packaging, agriculture, medical treatment and the like.

The invention provides a calcium fluoride sludge purification method, calcium fluoride fine powder and application thereof, and belongs to the field of calcium fluoride sludge treatment.The calcium fluoride sludge purification method comprises the following steps that calcium fluoride sludge and water are mixed to form a first mixed solution, a phosphate conversion agent is added, heating and stirring are conducted, and then filtering is conducted to obtain a first solid mixture; adding an acid solution into the first solid mixture, heating, stirring and filtering to obtain a second solid mixture; and water, an inhibitor, a collecting agent and a foaming agent are sequentially added into the second solid mixture to form a third mixed solution, flotation is conducted, and calcium fluoride fine powder is obtained. Impurity elements can be removed through combination of phosphate conversion and a flotation method, and compared with a method for removing calcium phosphate and calcium sulfate through a chemical treatment method, the reagent dosage is greatly reduced, the temperature needed by conversion is low, the conversion time is short, and the cost is low.

The invention discloses a grading reaction crystallization recovery process and system for semiconductor fluorine-containing and phosphorus-containing waste liquid, the fluorine-containing and phosphorus-containing waste liquid and a lime solution react in a fluorine recovery crystallization reactor under the condition that the pH is 3-4 to form calcium fluoride crystals, and the calcium fluoride crystals are dehydrated to obtain calcium fluoride particle crystal products; the effluent of the fluorine recovery crystallization reactor, the calcium fluoride crystal dehydration filtrate, the lime solution and the calcium chloride solution react in a secondary reaction tank under the condition that the pH is 5-6, and calcium fluoride, fluorapatite, silicon dioxide and silicon-aluminum precipitates are removed through coagulation, flocculation and precipitation; effluent of the second-stage reaction tank, the lime solution and the calcium chloride solution react in the phosphorus recovery crystallization reactor under the condition that the pH is 7-8 to generate hydroxyapatite crystals, and the hydroxyapatite crystals are dehydrated to obtain hydroxyl calcium phosphate particle crystal products. Meanwhile, a high-purity calcium fluoride crystal product and a hydroxyl calcium phosphate crystal product are produced, and fluorine and phosphorus are recycled.

The invention provides a self-reinforced absorbable composite material containing a polyester fiber / calcium phosphate substance. The absorbable bone screw and the absorbable bone plate prepared from the polyester fiber self-reinforced absorbable composite material provided by the invention have the advantages that the mechanical property is obviously improved, the degradation rate is controllable, the bone tissue regeneration induction time is shortened, the aseptic inflammation is relieved, the individual difference is small, and the processing efficiency is obviously improved. According to the absorbable composite material prepared by the invention, the polyester fibers and the polyester matrixes are various, and the mechanical property and the degradation rate of the composite material can be regulated and controlled through matching and combination of the fibers and the matrixes, so that the clinical requirements of fixing different fracture injuries are met; moreover, high-activity calcium phosphate substances doped with specific elements such as zinc, strontium and magnesium are further adopted, so that the aseptic inflammation caused by acidic degradation substances can be relieved, and higher osteogenic activity, higher angiogenesis promoting capability and the like are realized, so that injured bone tissues are induced to be healed more quickly.

The invention relates to the technical field of biological tissue adhesives, in particular to a biological tissue adhesive composition. The biological tissue adhesive composition comprises a powder A, a powder B and a powder C, wherein the powder A is obtained by curing calcium silicate and acidic calcium phosphate in a curing liquid, curing, drying and crushing; powder B: bivalent metal salt; powder C: phosphorylated amino acid; and an aqueous solvent; the biological tissue adhesive is used for bone adhesion and bone repair. According to the biological tissue adhesive composition provided by the invention, a silicate / hydroxyapatite composite material with a bone induction function is synthesized through optimized bone cement reaction, a curing liquid is added to react with phosphorylated amino acid, and a bone adhesive material is obtained through organic and inorganic material coordination reaction; the bone repairing and regenerating capability and the bone bonding capability are good.

The invention discloses a method for preparing lithium phosphate with high efficiency and low cost, which comprises the following steps: roasting spodumene concentrate and phosphoric acid, and carrying out slurrying leaching and solid-liquid separation to obtain a lithium dihydrogen phosphate solution; the method comprises the following steps: evaporating and concentrating a lithium dihydrogen phosphate solution, regulating the pH value of the lithium dihydrogen phosphate solution to 7-8 by adopting ammonia water, adding calcium phosphate seed crystals, inducing to remove residual calcium ions and magnesium ions in the solution, and carrying out solid-liquid separation to obtain a phosphate solution containing lithium ions; and then adjusting the pH value back to 11-13 by adopting alkali for lithium precipitation to obtain a lithium phosphate solid, and washing and drying to obtain a battery-grade lithium phosphate product. According to the preparation process of the lithium phosphate, the spodumene is acidized and roasted by adopting phosphoric acid, and pulpified and leached, and calcium ions and magnesium ions in a solution are directly induced by adopting calcium phosphate seed crystals to form crystals to be separated out on the basis of a weakly alkaline condition, so that the process steps are simple and convenient, the subsequent purification procedure is omitted, and the preparation process is more suitable for industrialization; meanwhile, the lithium phosphate product with high purity and high yield can be obtained through the simple and convenient process, the purity can reach 99.5% or above, and the yield can reach 92% or above.

A bone graft composition comprising a calcium phosphate putty is provided. A method of repairing a bone defect in a patient by applying the bone graft composition is also provided.

The invention discloses a bone cement composite material with collapse resistance and a preparation method thereof, and belongs to the technical field of biomedical materials. The composite material comprises a solid phase part and a liquid phase part, the liquid phase part and the solid phase part are mixed according to the liquid-solid ratio of 0.35 mL / g to 0.6 mL / g; the solid phase part is composed of calcium sulfate powder and calcium phosphate powder, and the mass ratio of the calcium sulfate powder to the calcium phosphate powder is 85: 15; the liquid phase part is selected from carboxymethyl chitosan or a combination of carboxymethyl chitosan and sodium alginate. The bone cement composite material prepared by the preparation method disclosed by the invention has good biocompatibility; due to a gel network formed by carboxymethyl chitosan and sodium alginate, the compressive strength of the bone cement is remarkably improved, and the collapse resistance and injectable performance are excellent; meanwhile, the bone cement composite material promotes the attachment and proliferation of osteoblasts, and can induce osteogenic differentiation in vitro.

The invention belongs to the technical field of waste recovery, and discloses a method for comprehensively recovering tungsten and phosphorus from scheelite smelting slag and tungsten-containing waste, which comprises the following steps: mixing the tungsten-containing waste, the scheelite smelting slag containing calcium phosphate and sodium salt, roasting to obtain a roasted material, leaching the roasted material with water to obtain a sodium phosphate solution and water leaching slag, and the water leaching residues are subjected to alkaline leaching, and then a sodium tungstate solution and alkaline leaching residues are obtained. The invention further comprises application of the sodium phosphate solution to scheelite decomposition. According to the method, phosphorus in the scheelite smelting slag and tungsten in the tungsten-containing waste can be efficiently recycled while the low cost, the minimum environmental pollution and the operation convenience are kept, and therefore cyclic utilization and sustainable development of resources are powerfully promoted.

The present invention belongs to the technical field of phosphate ore beneficiation and relates to a large-scale process method for a siliceous-calcareous phosphate ore spiral chute. Specifically, it includes: (1) Raw ore desliming: The raw ore is deslimed, and the deslimed raw ore enters the next step; (2) Classification and gravity separation: The deslimed raw ore is classified into several relatively narrower particle sizes according to certain conditions, and the products of each particle size are respectively subjected to gravity separation using a chute (with a diameter greater than 1200 mm). The concentrates and tailings after gravity separation of the products of each particle size are respectively combined into gravity separation concentrates and gravity separation tailings; (3) Flotation of gravity separation products. The present invention adds desliming and classification and gravity separation operations, which can effectively reduce the problem of entrainment of fine particle sizes in each strip in the chute (with a diameter greater than 1200 mm) and the problem of poor separation accuracy of the chute (with a diameter greater than 1200 mm) caused by equal-settling particles, improve the grade difference between the concentrates and tailings separated by the chute (with a diameter greater than 1200 mm), enhance the adaptability of the reagents in the subsequent flotation process, and improve the fluidity of the flotation foam.

The invention provides functional compound feed for sows in the perinatal period as well as a preparation method and application of the functional compound feed, and relates to the technical field of livestock breeding. The functional compound feed for the sows in the perinatal period is prepared from the following raw materials in parts by mass: 55 to 60 parts of corn, 13 to 15 parts of soybean meal, 1 to 5 parts of fish meal, 6 to 8 parts of extruded soybeans, 2 to 8 parts of barley bran, 0.5 to 1.5 parts of soybean oil, 0.5 to 1.5 parts of glucose, 2 to 8 parts of wheat bran, 1 to 1.5 parts of dicalcium phosphate, 0.5 to 1.5 parts of calcium carbonate, 0.2 to 0.6 part of table salt, 0.05 to 0.2 part of baking soda, 0.05 to 0.2 part of 50 percent choline chloride and 2 to 5 parts of premix. 0.1 to 0.5 part of a composite additive; the compound additive is prepared from the following raw materials in parts by mass: 0.5 to 1 part of ligustrazine, 1 to 5 parts of aloe-emodin glycoside, 0.5 to 2 parts of magnolol and 3 to 5 parts of probiotic microcapsules. Aiming at the perinatal syndrome of the sows, by adjusting the composition and proportion of the raw materials of the compound feed and the preparation method of important raw materials, many problems caused by the perinatal syndrome of the sows are solved, and the compound feed has a good industrial application prospect.

The invention discloses a heavy metal-tolerant phosphate-solubilizing Leclercia adcarboxcarboxy YZ30 strain and application thereof, and belongs to the field of microorganisms, the strain is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC NO: M 20211025. The phosphorus solubilizing amount of the strain to insoluble inorganic phosphorus (calcium phosphate) reaches 705.82 mg / L, the phosphorus solubilizing amount to insoluble organic phosphorus (calcium phytate and calcium and magnesium phytate) reaches 698.89 mg / L and 688.48 mg / L, and the strain has high tolerance to heavy metals such as zinc, cadmium and chromium and can keep high phosphorus solubilizing amount under the maximum tolerance concentration of 1050 mg / kg (zinc), 450 mg / kg (cadmium) and 1248 mg / kg (chromium). In addition, the compound has a certain degradation effect on aniline, and the degradation rate is 32.94%. The strain has relatively strong phosphate solubilizing capacity and heavy metal tolerance, can be used for repairing and reclaiming heavy metal polluted land, and has a very wide application prospect.

The invention discloses a semiconductor industry fluorine-containing wastewater treatment system and method. The treatment system comprises an adjusting unit, a pretreatment unit, a phosphorus recovery unit, a biochemical treatment and membrane separation unit and a phosphorus release and calcium removal unit. The phosphorus release and calcium removal unit is used for releasing phosphorus in the membrane separation concentrated water and enabling the phosphorus and partial hydrolytic acidification water of the biochemical treatment and membrane separation unit to enter the phosphorus recovery unit after being subjected to rotational flow enrichment; the phosphorus recovery unit is used for inducing calcium ions and phosphate radical ions in the wastewater to quickly form calcium fluoride and calcium phosphate by taking unprecipitated calcium fluoride, newly generated calcium fluoride and calcium phosphate and calcium fluoride refluxed by the phosphorus release and calcium removal unit as crystal nucleuses by utilizing the high pH value of the pretreatment unit; and finally, the calcium ions are removed from the system in a physicochemical sludge discharge and phosphorus product recovery mode, so that the influence of the calcium ions on the MBR membrane is reduced, the phosphorus recovery rate is improved, the use amount of the precipitant and the sludge amount are reduced, the medicament consumption is reduced, and the stable operation of the biochemical system is ensured.

The invention discloses microcapsule powder for covering the oil smell of euphausia superba oil and a preparation method of the microcapsule powder, and belongs to the field of euphausia superba oil processing. The microcapsule powder is composed of 50-75% of OSA starch, 10-30% of euphausia superba oil, 3-20% of sodium alginate, 1-10% of succinic acid and 0.5-5% of calcium hydrophosphate, during preparation, the OSA starch is gelatinized and then sheared and homogenized with the euphausia superba oil to obtain a miniemulsion, the succinic acid, the sodium alginate and the calcium hydrophosphate are prepared into a mixed solution, the mixed solution is mixed with the miniemulsion in proportion, and spray drying is performed to obtain a finished product. An OSA starch-sodium alginate double-wall material system is adopted, a compact cross-linked layer is formed through pH response, peculiar smell substances such as trimethylamine can be completely masked, the astaxanthin retention rate is up to 95.14%, the embedding rate reaches 89.48%, krill oil oxidation is effectively inhibited, krill oil is converted into powder, the stability and the sensory property are improved, application of krill oil in the food field is widened, the technology is simple, and the method is suitable for industrial production. The method is suitable for industrial production.

The invention discloses cefixime granules and a preparation method thereof, the granules comprise cefixime, a filler, an adhesive, a wetting agent, a flavoring agent and pharmaceutically acceptable auxiliary materials, and the filler is a calcium hydrophosphate-hydroxyethyl cellulose compound. The cefixime granules prepared by the invention are simple in preparation method, stable in quality, non-degradable, not easy to generate impurities, better in suspension performance, better in dissolution performance, qualified and stable in quality after long-term storage, simple in preparation process and suitable for industrial mass production under damp and hot conditions.

The present invention relates to a bone trauma repair bone paste and a preparation method thereof, belonging to the technical field of biomedical material manufacturing. The bone paste of the present invention is prepared by mixing nano calcium phosphate biphasic ceramics, biomimetic mineralized collagen fibers, biodegradable polymers, modified hyaluronic acid, β-cyclodextrin-coated recombinant human bone morphogenetic protein-7, angiogenesis promoters and immunomodulatory additives in a certain proportion; the nano calcium phosphate biphasic ceramics are hydroxyapatite and β-tricalcium phosphate biphasic ceramics; the biomimetic mineralized collagen fibers are prepared by mineralizing freeze-dried fibers of type I collagen admixed with hydroxypropyl chitosan; the modified hyaluronic acid is hyaluronic acid-thiol and hyaluronic acid-hydrazide; the angiogenesis promoter is a polylactic acid sustained-release microsphere loaded with tanshinone and hydroxy polyethylene glycol biotin; the immunomodulatory additive is disodium glycyrrhizinate, lentinan and astragalus polysaccharide. The bone paste can effectively improve the bone induction ability, promote angiogenesis and reduce the risk of immunogenicity.

The present invention relates to a composition of a ready to mix drink with green coffee extract as the main component. The current embodiment of our present invention includes three types of composition to provide flavour difference. Namely, mocha coffee, roasted coffee and cappuccino coffee flavour. The main components of the composition include the following ingredients in all the variants namely green coffee extract (50%), pullulan, propylene glycol, maltodextrin, polyethylene oxide, glycerol, polysorbate 80, sorbitol, nuesilin UFL2. Di basic calcium phosphate anhydrous, with only the flavoring agent as the changeable component to the composition.

The invention provides a step-by-step recycling and high-valuing method for sludge phosphorus, and belongs to the technical field of sludge treatment and recycling. The method comprises the following steps: carrying out pyrohydrolysis reaction and acid leaching treatment on phosphorus-containing sludge to obtain first phosphorus-rich supernate; under the temperature control condition, by adjusting the molar ratio of iron ions to phosphate ions in the first phosphorus-rich supernate and the pH value, a first crystallization reaction is carried out, and iron phosphate and second phosphorus-rich supernate are obtained; and then, adjusting the molar ratio and the pH value of calcium ions to phosphate ions in the second phosphorus-rich supernate, and carrying out a second crystallization reaction to obtain hydroxyapatite. Lithium iron phosphate can be synthesized by taking the iron phosphate as a raw material through a carbon thermal reduction method; the hydroxyapatite is used as a raw material, and the iron calcium phosphate is prepared through a solid-phase synthesis method. According to the method, the sludge phosphorus recovery rate is increased by more than two times, the phosphorus recovery chemical product value is high, and the value closed loop of sludge phosphorus recovery is realized for the first time.