54 results about "Dentin" patented technology

Methods and kits of materials and supplies for restoring teeth by an injection molding process and / or mold overlays in situ in a patient's mouth so as to correct the imperfect teeth of the patient's dentition. The imperfect teeth are corrected by applying restoration materials using a mold of a corrected model of the patients dentition placed over the imperfect teeth. Adjacent teeth may be covered with a polymer release material prior to injection molding of teeth to be corrected, such that the teeth to be corrected have at least one tooth between them draped with the polymer release material to provide a space adjacent to each of the corrected teeth. The corrected teeth are then covered with the polymer release material in a second round of treatment and restoration material is applied to one or more previously covered teeth to provide a first layer which simulates the dentin layer of teeth. Thereafter a simulated enamel layer is applied over the dentin layer using one or more alternating molds and yet another simulated incisal layer is applied over the enamel layer using one or more alternating molds employing the techniques described.

Method for electronically indicating a concentration of an irrigation solution in a root canal (RC) of a tooth (T), using a device able to be electrically connected to an endodontic instrument engaged in the canal and to a labial electrode, and including a screen to display the progression of the instrument in said canal relatively to a critical apical point of reference such as the cemento-dentinal junction (CDJ), said device being furthermore able to measure, in the vicinity of said point of reference, by conductimetry, a concentration of an electrolyte irrigation solution injected into the root canal.

The present application relates to a kind of tooth sample digestion system and method, belong to tooth sample detection field, for solving the tooth sample digestion system in prior art in peeling enamel, using diamond line to cut tooth, after cutting, using scalpel and forceps to separate enamel and dentin, and manually grinding enamel, it is difficult to operate, low efficiency Problem;Including: enamel separation mechanism, enamel grinding mechanism and enamel digestion mechanism.Enamel separation mechanism is provided with grinding separation module, enamel on tooth is directly ground down, enamel is stripped down in small granular or powder form, it is convenient for subsequent enamel grinding mechanism to grind it, after grinding, enamel will become more delicate, digestion effect is better, digestion is more complete.Enamel stripping does not need to cut tooth, can realize automatic operation throughout, high efficiency.

A method and apparatus for detecting a distance of a probe contacting a tooth surface to a pulp of a tooth by determining an indication of a thickness of a dentin of the tooth is provided. The method includes illuminating tooth tissue of the tooth with the probe and then receiving data indicative of scattered light from the tooth tissue. A spectrum of the scattered light is then acquired and analyzed to further acquire a spectral analysis result. An indication of the thickness of the dentin of the tooth is then determined based on the spectral analysis result. The method can help prevent accidental exposure of the pulp during dental treatments such as drilling.

This disclosure relates to systems and methods for the electrokinetic (EKF) delivery of therapeutic and cosmetic agents to oral tissues, including but not limited to enamel, dentin, cementum, gingiva, and mucosa. More specifically, it relates to modular, low-current dental treatment platforms configured to deliver active agents across or into oral tissues using flexible electrodes, voltage ramping logic, and optionally insulating or stabilizing structures.

The present application relates to the technical field of oral abrasive, in particular to a pectin-coated volcanic stone oral abrasive loaded with saussurea involucrate extract and a preparation method thereof. The oral abrasive comprises volcanic stone particles, saussurea involucrate extract, calcium pectin and an auxiliary agent. The volcanic stone particles serve as a natural porous abrasive, providing strength support and drug loading; the saussurea involucrate extract serves as an active ingredient, providing anti-inflammatory and antibacterial effects; the calcium pectin serves as a controlled-release agent and coating material, forming a gel network with calcium ions to control the release of the saussurea involucrate extract and wrapping the volcanic stone particles to form a flexible contact, buffering the direct friction of the abrasive on the tooth enamel; the components synergistically achieve the integrated effects of "physical cleaning-gel protection-traditional Chinese medicine treatment", ensuring the cleaning effect while reducing the dentin abrasion value, reducing the damage to the tooth enamel and effectively inhibiting oral pathogenic bacteria. The preparation method of the oral abrasive is simple, low in cost and has a broad application prospect.

The present disclosure describes compositions, kits and methods for promoting regeneration of dental tissue, particular dental pulp tissue. In some embodiments, a composition for promoting regeneration of dental tissue includes a dentin extracellular matrix material (dECM). In some embodiments, the dECM comprises dentin matrix proteins having an origin selected from human, ovine, porcine, and bovine.

The invention discloses a preparation method and application of a graded delivery system which takes a pH response type metal organic framework material NH2-MIL-101 (Fe) as a carrier and takes antibacterial peptide AMP and irisin as active ingredients. The graded delivery system comprises a metal organic framework material NH2-MIL-101 (Fe), AMP (adenosine monophosphate) and Irisin, wherein the AMP and the Irisin are loaded on the pH (potential of hydrogen) response type metal organic framework material NH2-MIL-101 (Fe). According to the system, aiming at periodontal and dental pulp infectious diseases, early-stage AMP rapid release for precise bacteriostasis and middle-stage Irisin synergistic release are realized through time sequence regulation and control to achieve anti-inflammatory and anti-oxidation effects, so that alveolar bone tissue / dentin regeneration is further promoted, and an excellent'antibacterial-anti-inflammatory-hard tissue regeneration 'cascade treatment effect is shown. The invention provides a new strategy and theoretical basis for precise treatment of periodontitis and pulpitis.

This disclosure relates to systems and methods for the electrokinetic (EKF) delivery of therapeutic and cosmetic agents to oral tissues, including but not limited to enamel, dentin, cementum, gingiva, and mucosa. More specifically, it relates to modular, low-current dental treatment platforms configured to deliver active agents across or into oral tissues using flexible electrodes, voltage ramping logic, and optionally insulating or stabilizing structures.

The application discloses a kind of intelligent preparation systems of laser navigation milk teeth root canal, it is related to milk teeth root canal treatment field, including: image processing module, self-checking registration module, structure acquisition module, spectral processing module, anomaly detection module, fusion determination module, compensation tracking module, digital modeling module, simulation learning module, trajectory generation module, execution monitoring module, safety protection module, interactive command module and record audit module;The application can more accurately distinguish infected dentin and healthy dentin, reduce the risk of misjudgment or missing infected areas, effectively reduce the risk of root tip penetration and root tip tissue damage, so that the laser cutting process always revolves around the real infected area, both can fully remove infected tissue, and can maximize the retention of healthy dental structure, improve root canal preparation efficiency and safety, reduce the dependence of doctors on experience judgment, so that milk teeth root canal preparation operation is more standardized and repeatable.

The present invention relates to a three-dimensional biomaterial comprising particles that encapsulate at least one complementary active fragment dispersed therein. The invention also relates to a process for manufacturing said biomaterial. This biomaterial is useful for tissue regeneration, especially of dental pulp, dentin, periodontal and gingival tissues, as well as bone tissues.

The invention discloses an intelligent labeling method and system based on an oral cavity CBCT image, and belongs to the technical field of oral cavity medical image processing, and the method comprises the steps: obtaining CBCT voxel data of a target tooth region; performing sliding window analysis on the CBCT voxel data to generate a local gray statistical feature of each sliding window; and for each sliding window, constructing a dual-modulation adaptive threshold function comprising a main threshold and an auxiliary threshold based on the local gray statistical characteristics, and carrying out joint judgment on the CBCT voxel data to form a preliminary tooth region. According to the scheme, through cooperative work of the main threshold value and the auxiliary threshold value, the judgment condition is dynamically adjusted in combination with the gray distribution similarity, the gray overlapping areas of the enamel, the dentin, the alveolar bone and other tissues can be effectively distinguished, and the problems that in the prior art, fixed threshold value segmentation is sensitive to local noise and cannot adapt to gray distribution changes are solved; and the accuracy and robustness of tooth region preliminary labeling are obviously improved.

The invention discloses a multi-material gradient bionic dental crown and a digital preparation method thereof, and belongs to the technical field of dental restoration materials and digital additive manufacturing. Comprising a dental crown body, the dental crown body is provided with a material structure of which the mechanical property continuously changes in a gradient manner along with the surface of a prepared tooth body, is formed by mixing two basic resin materials through voxel-level gradient in space, and is divided into two functional layers by imitating a double-layer hard tissue physiological structure of a natural tooth; comprising a high-wear-resistance bionic enamel layer used for forming the outer surface of a dental crown body and a high-toughness bionic dentin layer used for forming the dental crown body and connecting the high-wear-resistance bionic enamel layer and the surface of a prepared tooth body. By simulating a gradient structure of a natural tooth and a crack inhibition mechanism of the enamel-dentin boundary (DEJ), the fracture toughness and the anti-fatigue life of the dental crown body are far better than those of a traditional single-layer or layered all-ceramic crown, and thermal stress and mechanical stress are effectively buffered through modulus matching of the high-toughness bionic dentin layer and a resin adhesive.

Aqueous-based compositions for remineralizing dentinal tissues in vivo are disclosed to arrest demineralization and early-stage caries, treat dentin / tooth sensitivity, fix white spot lesions, and strengthen dentinal hard tissues (enamel, dentin, cementum), among others. Methods utilizing the remineralizing composition are also disclosed.

The present application relates to the technical field of composite materials, and particularly relates to a bioactive photocuring material, a preparation method thereof and application thereof as a dental substrate repair material. The bioactive photocuring material comprises a polymerizable monomer, an initiator and an inorganic filler, wherein the inorganic filler comprises calcium hydroxide; and further comprises a bioactive photocuring prepolymer, wherein the bioactive photocuring prepolymer is obtained by reacting a bioactive organic acid, a polyol monomer and a monomer containing a carbon-carbon double bond at 120-150 DEG C for 1-72 hours, and then neutralizing the reaction product with a neutralizing agent; and the monomer containing a carbon-carbon double bond is selected from at least one of a diol, a diacid and an anhydride. In the present application, the bioactive photocuring prepolymer is introduced into the calcium hydroxide system, so that the viscosity of the system is increased, the toughness, strength and degradability of the photocuring resin are enhanced, and the regeneration of bone and dentin is promoted by releasing active ingredients, and the bioactive photocuring material can be applied to a base material for caries filling and composite resin filling.

A method of stimulating dentin generation includes applying a polymerizable composition to exposed dental pulp in a dentate mammal or a dentate non-mammalian vertebrate; wherein the polymerizable composition comprises a hydroxy-substituted azobenzene group having the structure wherein x, R1, R2, R4, R5, R6, R7, R8, R9, and R10 are defined herein; and polymerizing the polymerizable composition; wherein the amount of the hydroxy-substituted azobenzene group applied to the exposed dental pulp is effective to promote dentin generation.

To provide a dental information processing device, a dental information processing system, a dental information processing method, a program, and a program storage medium that enable the efficient, rapid, and accurate creation of stored information such as dental medical records by mutually referencing findings information and analytical information in the operation of diagnosis and treatment in the field of dentistry. [Solution] In order to support accurate diagnosis and input of results when a dentist creates a dental chart during an initial consultation, a dental chart in which the dentist's findings from the appearance of the teeth are entered, an X-ray image of the tooth including at least the dentin bone, tooth root, and root remnant taken from an X-ray of the tooth, and AI judgment information superimposed on the X-ray image by AI are displayed on the same screen.

Desensitizing oral care composition useful for treating dentinal hypersensitivity, comprising potassium oxalate and methods of use thereof. Delivery systems including a strip of material and such oral care compositions for the treatment of dentinal hypersensitivity and methods of use thereof.

The invention provides mineralized hydrogel for functional regeneration and repair of hard tissues of a maxillofacial region and preparation of the mineralized hydrogel, and belongs to the field of bone repair materials. Wherein the hydrogel takes a dentin matrix as a mineralization core template, and is obtained by self-assembling gamma-polyglutamic acid, succinic anhydride modified chitosan and Ca < 2 + > on the template. The mineralization precursor which is stable in structure and excellent in biomimetic mineralization activity is successfully constructed, and a new material is provided for regeneration and repair of hard tissues of a maxillofacial region.

A phosphorous compound such as STMP is used as a cross-linking agent while making a starch nanoparticle in an emulsion process. Negative charge of the nanoparticle is reduced or reversed by adding cations and / or cationizing the starch optionally while forming the nanoparticles. Anionic active agents, such as fluoride or fluorescein, are optionally incorporated into the nanoparticle during the formation process. For example, a fluoride salt can also be used, which promotes the crosslinking reaction while also providing fluoride in the nanoparticle. The retention of both calcium and fluoride in the nanoparticle is improved when both salts are used. Alternatively, the nanoparticle may be used without added calcium and / or fluoride. The nanoparticles may be useful for tooth remineralization, the treatment of dentinal hypersensitivity, to treat caries, or as a diagnostic agent to locate carious lesions.

The application relates to the technical field of cell culture, and particularly discloses a method for constructing an in-vitro layered culture model for observing the polarity of odontoblasts, which comprises the following steps: extracting mandibular incisor neck ring tissues, separating dental epithelial tissues and dental papilla tissues; separately digesting the dental epithelial tissues and the dental papilla tissues into single-cell suspensions; inoculating epithelial cells on the surface of movable polycaprolactone films for culture to obtain an epithelial cell-polycaprolactone film complex; carrying out adherent culture on dental papilla cells to proliferate, and pre-treating the dental papilla cells under experimental conditions during or after the culture; inoculating the pre-treated dental papilla cells in an upper chamber; adhering the epithelial cell-polycaprolactone film complex to a lower chamber; and removing the epithelial cell-polycaprolactone film complex. By adhering the epithelial cell-polycaprolactone film to the lower chamber for co-culture, the epithelial cells can induce the dental papilla cells to establish top-bottom polarity by relying on the gap of the chamber.

A peptide composed of an amino acid sequence of the following General Formula 1: K—Y-R1-R2-R3-R4-R5-R6-R7-R8 (General Formula 1), a composition containing the peptide, and uses thereof are disclosed. In General Formula 1, R1 is arginine (R), lysine (K), or glutamine (Q); R2 is arginine (R) or glutamine (Q); R3, R4, and R5 are each arginine (R) or lysine (K); R6 is asparagine (N) or serine (S); and R7 and R8 are lysine (K) or tyrosine (Y). The composition is applied to the treatment of damaged dentin, such as dental caries or fractures, and thus can prevent possible dentin necrosis, dental extraction, or dental loss after treatment.

The invention relates to the technical field of cell culture, and particularly discloses an in-vitro layered culture model construction method for observing dentin cell polarity, and the method comprises the following steps: extracting mandibular incisor neck ring tissue, and separating odontogenic epithelial tissue from dental papilla tissue; respectively digesting the odontogenic epithelial tissue and the dental papilla tissue into single-cell suspensions; the method comprises the following steps: inoculating epithelial cells on the surface of a movable polycaprolactone membrane for culturing to obtain an epithelial cell-polycaprolactone membrane complex; performing adherent culture on the dental papilla cells for proliferation, and performing experimental condition pretreatment on the dental papilla cells in the culture process or after culture; inoculating the pretreated dental papilla cells into the upper chamber; the epithelial cell-polycaprolactone membrane complex is attached to a lower chamber; and the epithelial cell-polycaprolactone membrane complex is removed. Co-culture is realized by attaching an epithelial cell-polycaprolactone membrane to the lower part of the small chamber, and the epithelial cells can be utilized to induce dental papilla cells to establish top-bottom polarity by virtue of gaps of the small chamber.

Described herein are dental treatment compositions, more particularly, a dental varnish composition useful in effective fluoridation, enhancement of remineralization the tooth enamel, and hypersensitivity through occlusion of dentine tubule. The dental varnish composition includes a hydrogel system and at least one fluoride source, wherein the dental varnish is water soluble. The hydrogel system includes at least one polyphenol having at least one phenol group, at least one polymer, and a metal ion. Described herein are also methods of making dental varnish composition in a single step and one pot synthesis.

The invention provides bionic composite hydrogel and a preparation method and application thereof, and belongs to the technical field of medical materials.The bionic composite hydrogel is obtained by mixing CS-MA-GA dispersion liquid and SIS / nHAP dispersion liquid and then conducting a photo-crosslinking reaction, and CS-MA-GA is prepared through a reaction of methacrylic acid MA, chitosan CS and gallic acid GA; the SIS / nHAP is prepared from SIS collagen and hydroxyapatite. Gallic acid in CS-MA-GA and SIS collagen in the bionic composite hydrogel prepared by the invention construct a dual bonding mechanism, so that the material can be firmly and permanently combined with teeth in a humid oral environment, and micro-leakage is effectively prevented. The nano-hydroxyapatite plays a role in reinforcing the filler in a photo-crosslinking network, so that the compression modulus and the wear resistance of the hydrogel are remarkably improved, and the hydrogel can bear the occlusal force. Meanwhile, the SIS collagenous fibers are interwoven with the nHAP and CS-MA-GA network to form a bionic organic-inorganic composite structure, and the composition of natural dentin is highly simulated.

The invention discloses a semi-movable bionic false tooth which comprises a bionic tooth, the bionic tooth is fixed on a base plate, a retainer is arranged on the periphery of the bionic tooth, a tooth root part of the bionic tooth is embedded into an alveolar cavity, the base plate is attached to an oral mucosa on the periphery of the bionic tooth, so that the bionic tooth obtains mechanical support, and the retainer is used for connecting a natural tooth and the bionic tooth. Therefore, the bionic teeth are effectively fixed. The bionic dentin is porous ceramic jointly constructed by hydroxyapatite modified by hollow aluminum-oxygen cluster porous balls and calcium silicate, hydrogel is filled in the hollow aluminum-oxygen cluster porous balls and in macroporous channels and mesoporous channels of the porous ceramic, and the components of the hydrogel are the same as those of the hydrogel of the bionic dental pulp (3). The invention can promote oral wound healing, treat or prevent oral inflammation, increase the retention ability of false teeth and reduce the absorption speed of alveolar bones, and is especially suitable for teenagers and patients with weak physique and easy infection.

The invention discloses a modified chitosan-hydroxyapatite composite material as well as a preparation method and application thereof, and relates to the technical field of dental materials. The problems that an existing oral care product and a chitosan-hydroxyapatite composite material are narrow in antibacterial spectrum, not lasting in dentin desensitization effect, low in remineralization efficiency, poor in stability and difficult to give consideration to biological safety are solved. The preparation method of the modified chitosan-hydroxyapatite composite material comprises the following steps: dropwise adding an acetic acid aqueous solution of chitosan into an aqueous solution containing alkaline amino acid and a carboxyl activator, and carrying out mixed reaction, dialysis, filtration and freeze drying to obtain alkaline amino acid modified chitosan; dropwise adding a hydroxyapatite aqueous solution into the alkaline amino acid modified chitosan aqueous solution to carry out self-assembly reaction, centrifuging, taking supernate, filtering, and freeze-drying to obtain the modified chitosan-hydroxyapatite composite material. The prepared modified chitosan-hydroxyapatite composite material can be applied to the fields of oral care materials and nano sustained-release drug carriers.

The invention discloses a dental antibacterial adhesive and a preparation method thereof, and the dental antibacterial adhesive comprises the following components by mass: 40%-60% of a resin matrix material, 5%-20% of a diluent, 5%-20% of an acidic polymeric monomer, 0.3%-2% of a photoinitiator, 0%-2% of an auxiliary agent, 5%-15% of an antibacterial agent, 0.01%-0.1% of a stabilizer and 5%-20% of an inorganic filler. Polyphenols are used as antibacterial agents for preparation, and plant polyphenols have the functions of oxidation resistance, bacteria resistance, caries resistance, remineralization and the like. The method is suitable for bonding between the light-cured composite resin and dentin and enamel, including bonding in the process of directly filling and repairing various types of composite resin; and the adhesive can also be used for bonding in the process of repairing ceramic, composite resin and metal restoration by light-cured composite resin.

System for diagnosis, planning and guided execution of dental preparations in fixed prostheses, comprising a computer system, with respective hardware and software components, as well as further dedicated peripherals, which implements a process characterized by the following steps: A) preliminary diagnosis of the elements to be submitted to a prosthetic process : A.l) evaluate the dental element(s) and related prosthetic process, A.2) evaluate the bone support, including ratio of intraosseous and extraosseous dental portion, and distance and divergence between teeth to be connected, and A.3) evaluate the internal structure, e.g. enamel, dentin, pulp, cement, material for reconstruction; B) planning of ideal dental preparation(s) : B.l) superimpose an ideal prosthetic project to an initial anatomical dental situation; B.2) define a final subgingival / juxtagingival / supragingival preparation; and B.3) starting from an ideal tooth volume, reduce the volume so as to simulate the ideal dental preparation, taking into due consideration: B.3.1) the extent of the reduction depending on the material that will be used to construct the crown, e.g. metal-ceramic, zirconia, zirconia-ceramic, composite, disilicate lithium, ceramic, B.3.2) insertion axis of the prosthesis, where multiple dental elements should be parallelized in order to have a common insertion axis, and B.3.3) inclination of the prosthesis walls, which could be more or less retentive from a mechanical point of view; C) diagnosis of the ideal dental preparation(s) generated: C.l) evaluate the proximity to the pulp in the dental vital elements, including the need of root canal therapy related to vital dental elements, C.2) evaluate the structural surface composition of an ideal abutment, including percentage of enamel / dentin / reconstruction material, in order to assess retention adhesive of the substrate, C.3) evaluate, starting from the final preparation, the quantity of healthy dental tissue in terms of height - splint / cerclage effect, in order to define the mechanical stability of the preparation; D) transfer the ideal dental preparation into the oral cavity of a real patient according to two possible options: a) develop a tooth-supported transfer mask with guide tracks for dedicated drills with

The present invention relates to a dental prosthesis having a structure similar to a natural tooth and a method for manufacturing the same, and discloses a dental prosthesis which is a solidified product containing ceramic particles dispersed in a polymer matrix, and a method for manufacturing the same using a 3D printing method, the dental prosthesis comprising: a first solidified product layer having a content of ceramic particles of 70 to 90 wt%, and an average particle diameter of the ceramic particles of 100 to 1000 nm; and a second solidified product layer which is adjacent to an inner side of the first solidified product layer, has a content of ceramic particles of 40 to 60 wt%, and an average particle diameter of the ceramic particles of 10 to 500 µm. Thus, the dental prosthesis exhibits a structure similar to a natural tooth, i.e., exhibits a structure and physical properties similar to a natural tooth having a surface of enamel and an interior of dentin.