88 results about "Dentin" patented technology

The invention discloses a tooth wear evaluation model for evaluating the safety of oral products and a preparation method and application thereof. The tooth wear evaluation model is at least obtained by grinding and polishing the surface of a tooth model, and the tooth model comprises at least one of an animal enamel block model, an animal dentin block model, a tooth-like material dental film model, a full-mouth animal enamel model and a tooth-like material full-mouth tooth model. According to the tooth wear evaluation model, the wear performance of the oral product can be conveniently tested in vitro.

The present invention relates to diagnostic intraoral scanning and tracking. The present invention relates to methods and apparatus for acquiring, using, and displaying a three-dimensional (3D) volume model of a patient's dental arch. The 3D volume model may include surface information (e.g., color) as well as information about internal structures (e.g., near-infrared (Near-IR) transparency values ​​of internal structures including enamel and dentin).

Methods and kits of materials and supplies for restoring teeth by an injection molding process and / or mold overlays in situ in a patient's mouth so as to correct the imperfect teeth of the patient's dentition. The imperfect teeth are corrected by applying restoration materials using a mold of a corrected model of the patients dentition placed over the imperfect teeth. Adjacent teeth may be covered with a polymer release material prior to injection molding of teeth to be corrected, such that the teeth to be corrected have at least one tooth between them draped with the polymer release material to provide a space adjacent to each of the corrected teeth. The corrected teeth are then covered with the polymer release material in a second round of treatment and restoration material is applied to one or more previously covered teeth to provide a first layer which simulates the dentin layer of teeth. Thereafter a simulated enamel layer is applied over the dentin layer using one or more alternating molds and yet another simulated incisal layer is applied over the enamel layer using one or more alternating molds employing the techniques described.

The invention relates to the technical field of dental intelligent adjuvant therapy, and discloses an adjuvant therapy system and method for difficult-to-inverse suppurative periapical periodontitis, and the system comprises a multi-modal image fusion module which fuses CT / OCT images to generate a three-dimensional diagram, segments an infected region through a lightweight CNN, and outputs a probability diagram; the reinforcement learning debridement navigation module is used for optimizing the dentin injury risk by combining a biological membrane thickness dynamic planning path on the basis of a DDPG algorithm; the intelligent medicine control module is used for positioning a catheter according to an infection map, triggering medicine release by a pH / enzyme sensor and adjusting delivery pressure by PID; the biosensor monitoring module is used for detecting inflammatory factors, predicting the recurrence risk through LSTM, and triggering image rescanning and path updating when a threshold value is exceeded. Through multi-modal image fusion, reinforcement learning dynamic debridement navigation, microenvironment response type drug control and time sequence prediction closed-loop feedback, accurate elimination and relapse active inhibition of periapical periodontitis focuses are realized.

A method for determining a dental condition comprising: receiving at least one volumetric image and at least one intra-oral surface scan image of a dental structure of a patient, wherein the dental structure includes at least one of a crown, root, gingiva or bone; aligning the at least one volumetric image with the at least one intra-oral surface scan image; identifying boundaries of the gingiva and the bone within the aligned images; and calculating distances between the identified boundary of the gingiva and cementoenamel junction (CEJ), the identified boundary of the bone and the CEJ, and the identified boundary of the gingiva and the identified boundary of the bone to determine the dental condition.

The invention belongs to the technical field of biomedical materials, and particularly relates to a light-cured calcium hydroxide bottom-covering pith-covering material and a preparation method thereof.The light-cured calcium hydroxide bottom-covering pith-covering material is prepared from, by mass, 1%-10% of calcium hydroxide, 10%-40% of acrylate monomers, 1%-10% of amphiphilic acrylate phosphate radical monomers, 0.1%-1% of a photoinitiator, 0.01%-0.1% of an inhibitor and the balance filler; wherein the amphiphilic acrylate phosphate radical monomer is neutralized by strong base; according to the preparation method disclosed by the invention, the amphiphilic acrylate phosphate radical monomer is neutralized by the strong base, so that the phenomenon that the amphiphilic acrylate phosphate radical monomer reacts with calcium hydroxide in advance to cause that a material is changed into a caking state from a flowing state is avoided; and meanwhile, the amphiphilic acrylate phosphate radical monomer neutralized by the strong base can still form a chemical bond with dentin in use, so that the phenomenon that the traditional light-cured calcium hydroxide underlayer pulp covering material falls off when encountering water in the dental restoration process is prevented.

Method for electronically indicating a concentration of an irrigation solution in a root canal (RC) of a tooth (T), using a device able to be electrically connected to an endodontic instrument engaged in the canal and to a labial electrode, and including a screen to display the progression of the instrument in said canal relatively to a critical apical point of reference such as the cemento-dentinal junction (CDJ), said device being furthermore able to measure, in the vicinity of said point of reference, by conductimetry, a concentration of an electrolyte irrigation solution injected into the root canal.

The present application relates to a kind of tooth sample digestion system and method, belong to tooth sample detection field, for solving the tooth sample digestion system in prior art in peeling enamel, using diamond line to cut tooth, after cutting, using scalpel and forceps to separate enamel and dentin, and manually grinding enamel, it is difficult to operate, low efficiency Problem;Including: enamel separation mechanism, enamel grinding mechanism and enamel digestion mechanism.Enamel separation mechanism is provided with grinding separation module, enamel on tooth is directly ground down, enamel is stripped down in small granular or powder form, it is convenient for subsequent enamel grinding mechanism to grind it, after grinding, enamel will become more delicate, digestion effect is better, digestion is more complete.Enamel stripping does not need to cut tooth, can realize automatic operation throughout, high efficiency.

A method and apparatus for detecting a distance of a probe contacting a tooth surface to a pulp of a tooth by determining an indication of a thickness of a dentin of the tooth is provided. The method includes illuminating tooth tissue of the tooth with the probe and then receiving data indicative of scattered light from the tooth tissue. A spectrum of the scattered light is then acquired and analyzed to further acquire a spectral analysis result. An indication of the thickness of the dentin of the tooth is then determined based on the spectral analysis result. The method can help prevent accidental exposure of the pulp during dental treatments such as drilling.

This disclosure relates to systems and methods for the electrokinetic (EKF) delivery of therapeutic and cosmetic agents to oral tissues, including but not limited to enamel, dentin, cementum, gingiva, and mucosa. More specifically, it relates to modular, low-current dental treatment platforms configured to deliver active agents across or into oral tissues using flexible electrodes, voltage ramping logic, and optionally insulating or stabilizing structures.

The present application relates to the technical field of oral abrasive, in particular to a pectin-coated volcanic stone oral abrasive loaded with saussurea involucrate extract and a preparation method thereof. The oral abrasive comprises volcanic stone particles, saussurea involucrate extract, calcium pectin and an auxiliary agent. The volcanic stone particles serve as a natural porous abrasive, providing strength support and drug loading; the saussurea involucrate extract serves as an active ingredient, providing anti-inflammatory and antibacterial effects; the calcium pectin serves as a controlled-release agent and coating material, forming a gel network with calcium ions to control the release of the saussurea involucrate extract and wrapping the volcanic stone particles to form a flexible contact, buffering the direct friction of the abrasive on the tooth enamel; the components synergistically achieve the integrated effects of "physical cleaning-gel protection-traditional Chinese medicine treatment", ensuring the cleaning effect while reducing the dentin abrasion value, reducing the damage to the tooth enamel and effectively inhibiting oral pathogenic bacteria. The preparation method of the oral abrasive is simple, low in cost and has a broad application prospect.

The invention relates to the technical field of root canal treatment, in particular to a method, device and control equipment for controlling a root canal file based on dynamic torque, in the process that the root canal file is inserted into a root canal part and makes contact with dentin, real-time torque data generated by resistance in the process that the root canal file makes contact with the dentin are collected, and the real-time torque data are obtained; the method comprises the following steps: acquiring a real-time torque of a root canal part, performing target torque analysis matched with the real-time torque, so that the analyzed target torque meets the cutting requirement of the current dentin of the root canal part, and then controlling a root canal file to cut the dentin based on the analyzed target torque, so that the diameter change of the root canal file adapts to a root canal anatomical structure. The control accuracy of the torque of the root canal file is improved, so that the cutting accuracy, efficiency and safety of dentin are improved, the efficiency, accuracy and safety of root canal treatment are improved, and the user experience is improved. Meanwhile, the damage conditions such as bending and breakage of the root canal file can be reduced, and the service life of the root canal file is prolonged.

The invention relates to the technical field of oral medicine, in particular to a DNMTi and ZIF-8 nano-complex and application thereof.The DNMTi and ZIF-8 nano-complex is technically characterized in that in-situ synthesized zeolite imidaze-8 (ZIF-8) is adopted for delivering a DNA methyltransferase inhibitor (DNMTi), dental pulp stem cell (DPSC) cell spheres are combined, the DNMTi and ZIF-8 nano-complex can be used for bionic therapy, the activity of medicine is prolonged, and the effect of treating dental pulp stem cells is achieved. And zinc ions are continuously released to activate a PI3K-AKT signal channel, so that the dentin differentiation of stem cells and the generation of blood vessels are promoted. Through accurate simulation of a tooth development microenvironment, the biomimetic therapy can realize regeneration of a dental pulp-dentin complex. The therapy for simulating the tooth development process not only solves the key problems in the dental tissue engineering, but also opens up a new direction for treating the dental pulp and periapical diseases, and highlights the wide application prospect in regenerative medicine.

The present disclosure describes compositions, kits and methods for promoting regeneration of dental tissue, particular dental pulp tissue. In some embodiments, a composition for promoting regeneration of dental tissue includes a dentin extracellular matrix material (dECM). In some embodiments, the dECM comprises dentin matrix proteins having an origin selected from human, ovine, porcine, and bovine.

The invention discloses a preparation method and application of a graded delivery system which takes a pH response type metal organic framework material NH2-MIL-101 (Fe) as a carrier and takes antibacterial peptide AMP and irisin as active ingredients. The graded delivery system comprises a metal organic framework material NH2-MIL-101 (Fe), AMP (adenosine monophosphate) and Irisin, wherein the AMP and the Irisin are loaded on the pH (potential of hydrogen) response type metal organic framework material NH2-MIL-101 (Fe). According to the system, aiming at periodontal and dental pulp infectious diseases, early-stage AMP rapid release for precise bacteriostasis and middle-stage Irisin synergistic release are realized through time sequence regulation and control to achieve anti-inflammatory and anti-oxidation effects, so that alveolar bone tissue / dentin regeneration is further promoted, and an excellent'antibacterial-anti-inflammatory-hard tissue regeneration 'cascade treatment effect is shown. The invention provides a new strategy and theoretical basis for precise treatment of periodontitis and pulpitis.

The invention relates to a three-platinum-root-rehmannia root gargle and a preparation method and application thereof, and belongs to the technical field of oral medicine and traditional Chinese medicine application. The invention provides a three-platinum radix rehmanniae gargle. The three-platinum radix rehmanniae gargle comprises the following components in parts by mass: 1-10 parts of rhizoma bletillae, 1-10 parts of radix angelicae, 1-10 parts of rhizoma corydalis, 1-10 parts of cortex dictamni, 1-10 parts of fructus kochiae, 1-10 parts of honeysuckle, 1-5 parts of borneol and 1-5 parts of pseudo-ginseng. The three-platinum-radix rehmanniae gargle provided by the invention locally acts on sensitive areas of diseased teeth and is gargled after treatment, so that the three-platinum-radix rehmanniae gargle has the effects of diminishing inflammation, inhibiting bacteria, resisting tooth sensitivity, dispersing blood stasis, stopping bleeding, promoting tissue regeneration, relieving pain, clearing away heat and toxic materials and the like, effectively relieves tooth pain or sensitivity and protects dental pulp. When being used for preparing the deep caries pulp-protecting treatment medicine, the compound can permeate into dentin or dental pulp in the deep caries pulp-protecting treatment process and after operation, and plays the roles of relieving pain, desensitizing, clearing away heat and toxic materials and the like, so that the dental pulp is protected, and toothache and tooth sensitivity are avoided.

This disclosure relates to systems and methods for the electrokinetic (EKF) delivery of therapeutic and cosmetic agents to oral tissues, including but not limited to enamel, dentin, cementum, gingiva, and mucosa. More specifically, it relates to modular, low-current dental treatment platforms configured to deliver active agents across or into oral tissues using flexible electrodes, voltage ramping logic, and optionally insulating or stabilizing structures.

The application discloses a kind of intelligent preparation systems of laser navigation milk teeth root canal, it is related to milk teeth root canal treatment field, including: image processing module, self-checking registration module, structure acquisition module, spectral processing module, anomaly detection module, fusion determination module, compensation tracking module, digital modeling module, simulation learning module, trajectory generation module, execution monitoring module, safety protection module, interactive command module and record audit module;The application can more accurately distinguish infected dentin and healthy dentin, reduce the risk of misjudgment or missing infected areas, effectively reduce the risk of root tip penetration and root tip tissue damage, so that the laser cutting process always revolves around the real infected area, both can fully remove infected tissue, and can maximize the retention of healthy dental structure, improve root canal preparation efficiency and safety, reduce the dependence of doctors on experience judgment, so that milk teeth root canal preparation operation is more standardized and repeatable.

The present invention relates to a three-dimensional biomaterial comprising particles that encapsulate at least one complementary active fragment dispersed therein. The invention also relates to a process for manufacturing said biomaterial. This biomaterial is useful for tissue regeneration, especially of dental pulp, dentin, periodontal and gingival tissues, as well as bone tissues.

The invention discloses an intelligent labeling method and system based on an oral cavity CBCT image, and belongs to the technical field of oral cavity medical image processing, and the method comprises the steps: obtaining CBCT voxel data of a target tooth region; performing sliding window analysis on the CBCT voxel data to generate a local gray statistical feature of each sliding window; and for each sliding window, constructing a dual-modulation adaptive threshold function comprising a main threshold and an auxiliary threshold based on the local gray statistical characteristics, and carrying out joint judgment on the CBCT voxel data to form a preliminary tooth region. According to the scheme, through cooperative work of the main threshold value and the auxiliary threshold value, the judgment condition is dynamically adjusted in combination with the gray distribution similarity, the gray overlapping areas of the enamel, the dentin, the alveolar bone and other tissues can be effectively distinguished, and the problems that in the prior art, fixed threshold value segmentation is sensitive to local noise and cannot adapt to gray distribution changes are solved; and the accuracy and robustness of tooth region preliminary labeling are obviously improved.

The present application provides a kind of dentin inducer for enhancing histone succinylation and its application, wherein the dentin inducer is dimethyl succinate.The present application finds that Wnt3a protein with clear odontogenic differentiation effect promotes odontogenic differentiation of dental pulp stem cells by increasing intracellular succinic acid content to induce histone succinic acid, and direct addition of succinic acid or succinic acid derivatives such as dimethyl succinate can play a Wnt3a replacement role, enhance stem cell histone succinylation and promote odontogenic differentiation of dental pulp stem cells.Furthermore, compared with Wnt3a protein class inducer, succinic acid or succinic acid derivative has the advantages of stable preparation and clear target, and is more suitable for clinical operation, which has important practical significance for promoting the clinical transformation of dental pulp dentin complex regeneration technology.

To provide a dental polymerizable composition that enables enhancement of adhesive strength to dentin.SOLUTION: A dental polymerizable composition comprises a monomer liquid containing a non-acidic monomer having an ethylenically unsaturated group and free from acidic groups, and a photoacid generator, the photoacid generator being solid in the monomer liquid and soluble in water.SELECTED DRAWING: None

The invention discloses a multi-material gradient bionic dental crown and a digital preparation method thereof, and belongs to the technical field of dental restoration materials and digital additive manufacturing. Comprising a dental crown body, the dental crown body is provided with a material structure of which the mechanical property continuously changes in a gradient manner along with the surface of a prepared tooth body, is formed by mixing two basic resin materials through voxel-level gradient in space, and is divided into two functional layers by imitating a double-layer hard tissue physiological structure of a natural tooth; comprising a high-wear-resistance bionic enamel layer used for forming the outer surface of a dental crown body and a high-toughness bionic dentin layer used for forming the dental crown body and connecting the high-wear-resistance bionic enamel layer and the surface of a prepared tooth body. By simulating a gradient structure of a natural tooth and a crack inhibition mechanism of the enamel-dentin boundary (DEJ), the fracture toughness and the anti-fatigue life of the dental crown body are far better than those of a traditional single-layer or layered all-ceramic crown, and thermal stress and mechanical stress are effectively buffered through modulus matching of the high-toughness bionic dentin layer and a resin adhesive.

Aqueous-based compositions for remineralizing dentinal tissues in vivo are disclosed to arrest demineralization and early-stage caries, treat dentin / tooth sensitivity, fix white spot lesions, and strengthen dentinal hard tissues (enamel, dentin, cementum), among others. Methods utilizing the remineralizing composition are also disclosed.

The present application relates to the technical field of composite materials, and particularly relates to a bioactive photocuring material, a preparation method thereof and application thereof as a dental substrate repair material. The bioactive photocuring material comprises a polymerizable monomer, an initiator and an inorganic filler, wherein the inorganic filler comprises calcium hydroxide; and further comprises a bioactive photocuring prepolymer, wherein the bioactive photocuring prepolymer is obtained by reacting a bioactive organic acid, a polyol monomer and a monomer containing a carbon-carbon double bond at 120-150 DEG C for 1-72 hours, and then neutralizing the reaction product with a neutralizing agent; and the monomer containing a carbon-carbon double bond is selected from at least one of a diol, a diacid and an anhydride. In the present application, the bioactive photocuring prepolymer is introduced into the calcium hydroxide system, so that the viscosity of the system is increased, the toughness, strength and degradability of the photocuring resin are enhanced, and the regeneration of bone and dentin is promoted by releasing active ingredients, and the bioactive photocuring material can be applied to a base material for caries filling and composite resin filling.

A method of stimulating dentin generation includes applying a polymerizable composition to exposed dental pulp in a dentate mammal or a dentate non-mammalian vertebrate; wherein the polymerizable composition comprises a hydroxy-substituted azobenzene group having the structure wherein x, R1, R2, R4, R5, R6, R7, R8, R9, and R10 are defined herein; and polymerizing the polymerizable composition; wherein the amount of the hydroxy-substituted azobenzene group applied to the exposed dental pulp is effective to promote dentin generation.

To provide a dental information processing device, a dental information processing system, a dental information processing method, a program, and a program storage medium that enable the efficient, rapid, and accurate creation of stored information such as dental medical records by mutually referencing findings information and analytical information in the operation of diagnosis and treatment in the field of dentistry. [Solution] In order to support accurate diagnosis and input of results when a dentist creates a dental chart during an initial consultation, a dental chart in which the dentist's findings from the appearance of the teeth are entered, an X-ray image of the tooth including at least the dentin bone, tooth root, and root remnant taken from an X-ray of the tooth, and AI judgment information superimposed on the X-ray image by AI are displayed on the same screen.

The invention provides a dental acid etching agent, a preparation method thereof and a dentin surface treatment method. The dental acid etching agent comprises phosphoric acid and a functional resin monomer composition, on the basis of the dental acid etching agent, the functional resin monomer composition comprises 1-10 wt% of an acidic resin monomer and 1-5 wt% of an aldehyde group-containing resin monomer. The problem of nano leakage can be relieved, the durability and stability of bonding repair are improved, and the application prospect is wide.

The application discloses a YWHAH active polypeptide and a preparation method and application thereof, and belongs to the field of biological medicine and tissue engineering. The polypeptide sequence is LRDNLTLWTSDQQDE or TLWTSDQQDEEAGEG, which can target and block the GREM1 / YWHAH protein complex, and release the inhibition of GERM1 on the BMP signal pathway. Experiments prove that the polypeptide can significantly improve the osteogenic and dentinogenic differentiation ability of dental pulp mesenchymal stem cells, up-regulate the alkaline phosphatase activity and cell mineralization level, promote the expression of osteogenic and dentinogenic marker genes, and induce the formation of bone-like and dentin-like new tissues in vivo. The polypeptide has the advantages of small molecular weight, convenient chemical synthesis, good physicochemical stability, weak immunogenicity and the like, and can be used in stem cell culture preparations, composite tissue engineering scaffolds, local injection drugs and various dosage forms, and has a wide application prospect in various hard tissue defect repair scenes.

Desensitizing oral care composition useful for treating dentinal hypersensitivity, comprising potassium oxalate and methods of use thereof. Delivery systems including a strip of material and such oral care compositions for the treatment of dentinal hypersensitivity and methods of use thereof.