The slimming toothpaste consists of plant extract in 5-8 wt% and toothpaste cream in 92-95 wt%. The plant extract is extracted from lotus leaf, gamboge fruit, Asiatic centella, aloe, mulberry, oolong, astragalus root and wolfberry fruit. The toothpaste cream consists of Carbogel, xanthan gum, CMC, saccharin sodium, sorbic alcohol, glycerin, sodium dodecyl sulfate, polyethylene glycol, polyester, silica, titania, preservative, essence and water. The present invention has functions of cleaning teeth and reducing weight. It reaches the function of reducing weight by means of the synergistic effects of promoting fat burning, reducing absorption to fat, inhibiting the conversion of carbohydrate to fat, raising metabolism level, promoting urination, nourishing Yin and invigorating Qi.