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494results about How to "Reduce stimulation" patented technology

Recombinant XVII type collagen for skin aging resistance as well as preparation method and application of recombinant XVII type collagen

The invention relates to an anti-aging oligopeptide for beauty and skin care, the oligopeptide has an amino acid sequence as shown in (X1) (R or K or H) G (D or E) # (X2), X1 represents one amino acid of G, A, V, L, I and P or represents that no amino acid exists, # represents one amino acid selected from A, V, D, E, N and Q, and X2 represents G and P or represents that no amino acid exists. The oligopeptide is a functional fragment of XVII type collagen, can induce in-vivo collagen synthesis or simulate a protein regulation function, has the effects of promoting cell self-cleaning, helping to remove aged skin cells, reconstructing skin rhythm, maintaining a good skin structure, resisting initial aging, promoting skin repair and regeneration, reducing fine wrinkles and the like, and is mild in action, free of side effects and free of toxic and side effects. The product has no obvious adverse reaction on human body, and is a good beautifying and anti-aging product.
Owner:杭州拾光欣雅生物技术有限公司

Probiotic enteric dry suspension as well as preparation method and application thereof

The invention provides a probiotic enteric dry suspension as well as a preparation method and application thereof, and relates to the technical field of pharmaceutical preparations. The probiotic enteric dry suspension comprises the following components in parts by mass: 1-8 parts of probiotic powder; 25 to 60 parts of a microcapsule cross-linking system; 1-15 parts of a suspending aid; 20 to 70 parts of a filling agent; 0-0.1 part of a coloring agent; and 0-1 part of an aromatic. According to the invention, when the probiotic powder is dispersed in water by utilizing the gelling property of sodium alginate, the probiotic powder is wrapped to form a probiotic-sodium alginate compound, citric acid and calcium carbonate are subjected to an acid-base reaction, and generated carbon dioxide bubbles can prevent the probiotic-sodium alginate compound from agglomerating; meanwhile, the released calcium ions and chitosan interact with the probiotic-sodium alginate compound, a compact probiotic microcapsule structure is rapidly and stably formed in one step, the probiotics in the microcapsule are effectively protected from being damaged by gastric acid and bile, the survival rate of the probiotics is increased, and the enteric effect is achieved.
Owner:SHENZHEN WANZE MICROBIOLOGY RESEARCH CO LTD

Periosteal distraction system and use method thereof

The invention provides a periosteum distraction system and a using method thereof, the periosteum distraction system comprises a periosteum distraction plate, a primary nail and a secondary nail, the periosteum distraction plate comprises a first distraction plate and a second distraction plate, and the first distraction plate and the second distraction plate are detachably connected; the periosteum distraction plate is provided with a first connecting part, the female nail is provided with a second connecting part, and the first connecting part is fixedly connected with the second connecting part; the female screw is of a hollow structure and is provided with an internal thread; the son nail is mounted in the mother nail, the son nail is provided with an external thread, and the external thread is matched with the internal thread of the mother nail; the son nail is rotated to enable the mother nail and the periosteum distraction plate to move in the axial direction of the son nail, and the end of the son nail protrudes out of the periosteum distraction plate. By using the technical scheme provided by the invention, the periosteum incision is smaller, the trauma to the periosteum is smaller, and the condition that the skin is stimulated when the periosteum is stretched is reduced.
Owner:SUZHOU & SCI & TECH DEV

Transfusion alarm

The utility model belongs to the technical field of infusion alarms, and particularly relates to an infusion alarm which comprises an alarm body and an infusion alarm device arranged on the alarm body. The supporting device comprises two fixing blocks which are symmetrically arranged on the rear side wall of the alarm main body and are provided with slots, and an inverted U-shaped supporting frame which is arranged between the two fixing blocks and is in sliding connection with the slots; the inverted U-shaped clamping frame is arranged at the tail end of the supporting frame; and the fastening rod is in threaded connection with the rear side wall of the clamping frame and is used for fixing the alarm main body and an infusion support. According to the infusion alarm device, the supporting device is arranged, so that the alarm device body can be conveniently fixed to an infusion support, the situation that the alarm device body is directly clamped on the outer side of an infusion tube and applies downward pulling force to the infusion tube is avoided, and the situation that the connecting position of the infusion tube and an infusion bottle falls off is avoided; and accompanying personnel and medical personnel can be reminded in time.
Owner:THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Chitosan hydrogel and preparation method thereof

The chitosan hydrogel disclosed by the invention is prepared from the following components in parts by weight: 6 to 15 parts of carboxymethyl chitosan, 0.4 to 1 part of a cross-linking agent and 300 to 900 parts of water. The invention belongs to the technical field of polymer hydrogel, and particularly relates to chitosan hydrogel and a preparation method thereof, the prepared chitosan hydrogel is low in toxicity and safer, a low-temperature and high-temperature step-by-step cross-linking product is adopted, compared with a one-step cross-linking product, the residual amount of a cross-linking agent is lower, a chitosan solution and the cross-linking agent react slowly under the low-temperature condition, and the cross-linking effect is good. The mixing is more sufficient under a liquid condition.
Owner:DEZHOU UNIV

Low-irritation essential oil hair dye and preparation method thereof

ActiveCN119405565Adesensitizationless discomfortCosmetic preparationsHair cosmeticsHair ColorantsStearyltrimethylammonium chloride
The invention relates to the field of hair dyeing products, in particular to a low-irritation essential oil hair dye and a preparation method thereof. The invention relates to a low-irritation essential oil hair dye, which comprises a No.1 agent and a No.2 agent, the No.1 agent comprises a humectant, a hair coloring agent, an antioxidant, a chelating agent and a solvent A; a thickening agent A, an emulsifier A and a hair conditioner; a pH regulator A, and polydimethylsiloxane; the disinfectant is prepared from an aromatic A, polyquaternium-7, polyquaternium-10, argania spinosa kernel oil, a camellia extract, a ginger root extract and a preservative; the agent 2 comprises a solvent B, cetearyl trimethyl ammonium chloride, sodium stannate and a pH regulator B; a thickener B, an emulsifier B and mineral oil; a chelating agent C; and an oxidant. The hair dye provided by the invention can reduce irritation under the condition of ensuring the hair dyeing effect and relieve the frizz degree of dyed hair, and has a plurality of advantages.
Owner:VENUS SKIN & HAIR LAB LTD +1

Glucoside derivative flexible liposome as well as preparation method and application thereof

The invention belongs to the field of personal care, and particularly relates to a glycoside derivative flexible liposome and a preparation method and application thereof, the glycoside derivative flexible liposome comprises a main shell material, a humectant, a wrapped raw material, an auxiliary shell material, a preservative and a solvent; the main shell material is phosphatidylcholine, and the auxiliary shell material is polyquaternium-51; the preservative is any one or more of 1, 2-hexanediol, p-hydroxyacetophenone, methylparaben, phenoxyethanol and caprylyl glycol; the moisturizing agent is butanediol; the wrapped raw material is hydroxypropyl tetrahydrofurantriol; the solvent is deionized water. According to the invention, the permeability and penetration depth of the glassine and the concentration of the glassine at a target position are improved by utilizing a flexible liposome wrapping technology, the bioavailability of the glassine is improved, and the addition amount is reduced under the condition of realizing the same tightening and anti-wrinkle effects, so that the cost is reduced.
Owner:SUZHOU MISIFU COSMETICS CO LTD

Selenium disulfide shampoo with good suspension effect and preparation method thereof

The invention discloses selenium disulfide shampoo with a good suspension effect and a preparation method of the selenium disulfide shampoo. The selenium disulfide shampoo comprises the following raw materials in percentage by weight: 0.05-1% of selenium disulfide particles; 0.2-6% of a high-molecular polymer capable of suspending selenium disulfide particles; 0.5 to 5% of a polyol; and 0.05%-0.1% of a chelating agent. The selenium disulfide shampoo has the advantage of being good in suspension effect, and the problems that in the using process of existing selenium disulfide shampoo, due to the fact that the dispersion uniformity and suspension stability of selenium disulfide in the shampoo are poor, the selenium disulfide is likely to be precipitated in a shampoo container, the concentration of the selenium disulfide before and after use is different, and the selenium disulfide cannot be precipitated in the shampoo container are solved. The treatment effect of the selenium disulfide shampoo on a patient is influenced.
Owner:SHAANXI JIABEINI BIOTECHNOLOGY CO LTD

Preparation method and application of artemisia apiacea fermentation extracting solution

The invention discloses a preparation method and application of an artemisia apiacea fermentation extracting solution. The artemisia annua fermentation extracting solution is prepared from artemisia annua, ultrapure water, probiotics and the like. The preparation method comprises the following steps: picking fresh artemisia annua, cleaning, drying and sterilizing; crushing, sieving, and selecting artemisia annua particles with proper particle sizes; adding the selected artemisia annua particles, ultrapure water and probiotics into a temperature-controlled closed stirring reaction device, and carrying out strict anaerobic fermentation; separating a liquid phase part and a solid phase part from the obtained fermentation product through five filtering processes, performing microfiltration on the liquid phase part to remove thalli, and adding 1, 2-hexanediol and p-hydroxyacetophenone to obtain the artemisia apiacea fermentation extracting solution. The extracting solution prepared by fermenting natural plant raw materials and probiotics is high in molecular weight uniformity and high in physiological activity, retains the functional effect of sweet wormwood, is safe, low in sensitivity and low in irritation, and is suitable for being added into various daily chemical products.
Owner:朱灵水

Hydrogel containing all-type sun-screening agent microbeads, preparation method and application

The invention relates to hydrogel containing all-type sun-screening agent microbeads, a preparation method and application, and belongs to the technical field of sun screening. Mixing, heating and dissolving the oil-soluble organic sun-screening agent to obtain the sun-screening oil; the preparation method comprises the following steps: mixing a sodium alginate solution, a PVA solution and an inorganic sun-screening agent (zinc oxide and titanium dioxide) to form a turbid liquid, and uniformly stirring to form a first mixture; preparing oil-in-water microspheres from the obtained sunscreen oil and the first mixture through a microfluidic technology, and dripping the oil-in-water microspheres into a calcium chloride solution to form light yellow sunscreen microspheres; adding carbomer sodium into water to form gel, then adding the water-soluble organic sun-screening agent, adding the pH regulator while heating and dissolving until the solution is transparent, then adding the active substance, and continuously stirring until the mixture is uniformly mixed to obtain a third mixture; adding a thickening agent to prepare hydrogel; and adding the sunscreen microbeads into the hydrogel to obtain a dispersion system containing all types of sunscreen microbeads. The invention solves the technical problem that the product in the existing sunscreen system is greasy and easily causes anaphylactic reaction.
Owner:JIANGNAN UNIV

Flexible circuit board

The flexible circuit board comprises a component layer, a surface insulating coating, a surface circuit layer, an FPC substrate layer, a bottom surface circuit layer and a bottom surface insulating coating which are sequentially distributed from top to bottom, the lower surface of the surface insulating coating is in face-to-face fit with the upper surface of the FPC substrate layer, the lower surface of the FPC substrate layer is in face-to-face fit with the upper surface of the bottom surface insulating coating, and the surface circuit layer is clamped between the lower surface of the surface insulating coating and the upper surface of the FPC substrate layer. The bottom surface circuit layer is clamped between the lower surface of the FPC substrate layer and the upper surface of the bottom surface insulating coating, and the surface circuit layer and the bottom surface circuit layer are respectively provided with circuits which operate independently and have different functions. Therefore, the design can provide the flexible circuit board which has different functions, operates independently and does not interfere with each other and is not less than two layers of circuits.
Owner:GUANGZHOU YANGSHI INTELLIGENT WEARING TECHNOLOGY CO LTD

Composition for cleaning or freshening hair or scalp and application thereof

The invention discloses a composition for cleaning or refreshing hair or scalp and application thereof, the composition takes N-long-chain acyl amino acid and basic amino acid as main surfactants, can not contain a thickening agent, ethoxylate, fatty acid salt and a humectant, has the properties of low irritation, selective cleaning, easiness in washing, no stickiness and the like, and can be used for cleaning or refreshing hair or scalp. The shampoo is especially suitable for no-wash or dry-wash shampoo products.
Owner:SUZHOU OULIT BIOPHARM CO LTD

Multifunctional nasopharynx ventilation catheter for breathing machine

The invention discloses a nasopharynx ventilation catheter for a multifunctional breathing machine. The nasopharynx ventilation catheter comprises a flexible catheter body, an anti-bending supporting part, a dosing assembly, a sputum suction assembly, a monitoring assembly and an air bag mechanism. The air outlet end of the flexible conduit is provided with an antibacterial conduit head, and the air inlet end is provided with a connecting assembly; the antibacterial catheter head is provided with a hole channel assembly and a medicine feeding opening, and the flexible catheter is provided with a suction opening. The anti-bending supporting part is mounted on the inner wall of the flexible conduit; one end of the dosing assembly is communicated with the dosing port; one end of the sputum suction assembly is communicated with the suction port; the detection end of the monitoring assembly is located in the inner cavity of the flexible catheter and close to the duct assembly, and the monitoring assembly is used for monitoring the concentration of carbon dioxide in the oral and nasal cavity; the air bag mechanism comprises a first air bag, a second air bag and two air bag air supply assemblies. The device has the functions of drug delivery, sputum suction, carbon dioxide concentration monitoring and the like, meanwhile, the nasal mucosa can be free of damage or obviously relieved, the device can be conveniently inserted into the nasal cavity, the fixing effect is good, and the ventilation effect is good.
Owner:JINING NO 1 PEOPLES HOSPITAL (JINING ACAD OF MEDICAL SCI)

Intelligent lavage and drainage system for gastrointestinal surgery

The invention discloses an intelligent lavage and drainage system for gastrointestinal surgery in the technical field of gastrointestinal surgery, and the system comprises an information collection module which is used for collecting gastrointestinal pressure information of a patient and recording and storing the pressure information; the data analysis and processing module is used for establishing a pressure model and a pressure threshold value by utilizing a machine learning algorithm based on the collected pressure information; the intelligent control module is used for controlling the flow speed and flow of the lavage fluid and the drainage fluid in different time periods according to the pressure information; and the early warning module is used for monitoring abnormal conditions of the gastrointestinal tract, automatically starting a drainage function and sending out an alarm signal when monitoring that the pressure information exceeds a preset pressure threshold value. By analyzing the relevance between various characteristic information and gastrointestinal tract environment information of the patient, the lavage and drainage parameters are automatically adjusted according to individual differences of the patient, and a more personalized treatment scheme can be provided, so that the treatment effect is improved.
Owner:JIANGYIN PEOPLES HOSPITAL

Calculus flushing device for urinary surgery and use method of calculus flushing device

The invention belongs to the technical field of medical instruments, particularly relates to a urinary surgery calculus flushing device and a use method thereof, and aims to overcome the defects that in the prior art, calculus cannot be collected, and the water pressure of cleaning fluid cannot be adjusted when the calculus is flushed. A handle is fixedly mounted at the bottom of the mounting box, an outer hose is fixedly mounted on the inner wall of one side of the mounting box, one end of the outer hose extends to the outer side of the mounting box, an inner pipe is fixedly mounted in the outer hose, a downpipe is fixedly mounted on the inner wall of the bottom of the mounting box, and the bottom end of the downpipe extends to the position below the mounting box and is fixedly provided with a threaded sealing cover. When calculi in the urethra of a patient are flushed, stamping of cleaning liquid can be adjusted, so that discomfort is not increased when the patient is flushed, meanwhile, the crushed calculi can be sucked out in time, and the crushed calculi can be prevented from remaining in the urethra of the patient.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Intravascular stent

ActiveCN119235517AImprove radial supportstable supportStentsMedical deviceBiomedical engineering
The invention relates to the technical field of medical instruments, and particularly discloses an intravascular stent. The stent is tubular and comprises a plurality of supporting rings and a plurality of connecting rods, the supporting rings are arranged at intervals in the axial direction of the intravascular stent, and every two adjacent supporting rings are connected through the corresponding connecting rod; the intravascular stent comprises a middle area and two end areas which are arranged in the axial direction, the two end areas are located at the two axial ends of the intravascular stent respectively, the middle area is located between the two end areas, the portion, located in the middle area, of the supporting ring comprises a plurality of first supporting rods connected in the circumferential direction, and the portion, located in the end areas, of the supporting ring comprises a plurality of second supporting rods connected in the circumferential direction. The width of the first supporting rod is larger than that of the second supporting rod. According to the stent, the widths of the supporting rings of all parts are limited, so that the good flexibility of the two ends of the stent is guaranteed before the stent is expanded, the supporting force of the middle is high, and the passing ability of the stent is improved; the stent is axially retracted after being expanded and is uniform in shape, so that the bone effect of a dog is reduced.
Owner:SHANG HAI JING JIA SHAN YI LIAO KE JI YOU XIAN GONG SI

Liquid crystal screen backlight partition dynamic adjusting system for enhancing picture contrast

The invention relates to the technical field of liquid crystal display screen brightness adjustment, in particular to a liquid crystal display screen backlight partition dynamic adjustment system capable of enhancing picture contrast. The system comprises the steps of obtaining an image currently displayed by a liquid crystal screen, enhancing the local contrast of the image, determining a brightness influence coefficient equation of each partition according to an established backlight model, solving the brightness influence coefficient equation based on an optimization algorithm, determining a brightness influence coefficient of each partition, and displaying the brightness influence coefficient of each partition. And solving the brightness influence coefficient equation based on an optimization algorithm, determining the brightness influence coefficient of each partition, and adjusting the backlight brightness of the partitions based on a regional dynamic dimming algorithm. According to the invention, the brightness of each backlight subarea can be adjusted in real time according to the image content, so that black and white in the picture are darker, the contrast ratio is obviously improved, the backlight brightness is intelligently adjusted according to the brightness and color distribution of the image content, and unnecessary energy consumption is avoided.
Owner:GUANGZHOU CHANGJIA ELECTRONICS

Tab welding equipment for manufacturing composite current collector

The invention discloses tab welding equipment for manufacturing a composite current collector, and relates to the technical field of welding equipment, and the tab welding equipment comprises a composite mechanism. According to the tab welding equipment for manufacturing the composite current collector, through the design of the composite mechanism, materials are placed in the clamping mechanism, so that the effect of fixing the materials is achieved, the materials are prevented from moving or shaking in the welding process, and the influence on the welding effect and the welding precision is avoided; the sliding block drives the welding machine to move on the welding frame body to be attached to materials for laser welding, the positioning mechanism is attached to the surfaces of the materials in the welding process, so that the material welding precision is improved, the welding quality is improved, the welding frame body slides on the surfaces of the connecting rods, and the welding flexibility is improved; the limiting mechanism is used for limiting the moving range of the clamping mechanism, part abrasion caused by excessive sliding is avoided, and the service life of the equipment is prolonged.
Owner:AI MU XI AI (SU QIAN) DIAN CHI JI SHU YOU XIAN GONG SI

Local chemotherapy device for esophageal cancer

PendingCN119524302AImprove local treatment effectprevent flowMedical devicesTopical treatmentOncology
The invention discloses an esophageal cancer local chemotherapy device, and belongs to the technical field of chemotherapy auxiliary equipment, the esophageal cancer local chemotherapy device comprises a sealing device, the sealing device comprises a drug delivery tube, the lower end of the drug delivery tube is fixedly connected with a zigzag mounting tube, and the side wall of the zigzag mounting tube is rotatably connected with a plurality of hinge connecting rods; the lower end of the zigzag mounting tube is fixedly connected with a closed collecting film fixedly connected with the upper ends of the hinge connecting rods, the interior of the zigzag mounting tube is slidably connected with a movable block, and the device can be tightly attached to the inner wall of the esophagus through unfolding of the closed collecting film to form an effective closed structure, so that the position of medicine at the focus is locked, and the medicine is prevented from being damaged. Therefore, the local treatment effect of the medicine can be improved, meanwhile, the medicine is prevented from flowing to the stomach along with natural physiological movement of the esophagus, stimulation to the digestive tract of a patient is reduced, meanwhile, the influence on normal tissue of the patient is reduced, precise treatment is achieved, and the health of the patient is protected to the maximum extent.
Owner:THE FOURTH HOSPITAL OF HEBEI MEDICAL UNIVERSITY (HEBEI CANCER HOSPITAL)

Cleaning composition and application thereof

PendingCN119257962Areduce stimulationLow selective cleaning/decontaminationCosmetic preparationsHair removalShower gelActive agent
The invention discloses a cleaning composition, a related cleaning product and application of the composition in the aspects of reducing skin irritation or eye irritation, controlling oil, removing odor and the like, N-long-chain acyl amino acid and basic amino acid / inorganic base are used as main surface active agents, a thickening agent, ethoxylate, fatty acid salt and a humectant can be not contained, and the cleaning composition is mild and free of irritation; the compound can be used for shower gel, shampoo, cleansing mousse, cleansing products, oral washing products, shaving products, hand sanitizer, cleaning lotion or multifunctional cleaning products.
Owner:SUZHOU OULIT BIOPHARM CO LTD

Soluble microneedle patch, microneedle mask, microneedle smoking cessation patch and preparation method thereof

The invention relates to the technical field of external preparations, in particular to a soluble microneedle patch, a microneedle mask, a microneedle smoking cessation patch and a preparation method thereof.The soluble microneedle patch comprises a microneedle layer and a backing layer, the microneedle layer is prepared from a microneedle matrix solution, the backing layer is prepared from a backing matrix solution, and the backing matrix solution comprises hyaluronic acid and povidone K30; the mass ratio of the hyaluronic acid to the povidone K30 is (3-4): 1, and the concentration of the backing matrix solution is 1.2-1.8 g / ml. The problems that a soluble microneedle is insufficient in mechanical strength, cannot penetrate into the skin for administration, is prone to fragmentation during administration, and is high in pain feeling and poor in comfort can be solved.
Owner:CHONGQING MEDICAL & PHARMA COLLEGE

Out-of-focus and dot matrix composite lens

The utility model discloses an out-of-focus and dot matrix composite lens, which comprises a lens main body, a central optical correction area, a central out-of-focus prevention and control area and a peripheral out-of-focus prevention and control area are arranged in the lens main body, and dot matrix areas are arranged in gaps of the central out-of-focus prevention and control area and the peripheral out-of-focus prevention and control area. Compared with the prior art, the utility model has the advantages that the central defocusing prevention and control area and the peripheral defocusing prevention and control area are arranged outside the central optical correction area in a layered manner, so that the defocusing effect can be increased step by step, a transition effect is achieved, the initial wearing comfort is improved, the correction area and the transition area are more comfortable to convert, and the wearing comfort is improved. And meanwhile, a point diffusion technology is added in a defocus gap, so that the contrast sensitivity is further reduced, the stimulation of a high-contrast visual signal to retina cone cells is reduced, and the effect of delaying myopia development is improved.
Owner:HENAN BAOSHIDA VISUAL HEALTH TECH CO LTD

Lactoferrin and antibacterial peptide bifunctional hydrogel dressing as well as preparation method and application thereof

The invention discloses a lactoferrin and antibacterial peptide bifunctional hydrogel dressing as well as a preparation method and application thereof. The hydrogel dressing is prepared by mixing lactoferrin, antibacterial peptide NZ2114, a magnesium lithium silicate gel matrix and water. The hydrogel dressing provided by the invention has the following advantages: 1) the hydrogel dressing is simple to prepare, low in cost and suitable for batch production; 2) the gel is convenient to apply, has a moisturizing effect, is long in residence time, good in biocompatibility, small in irritation, safe and reliable, or is accurately injected to the wound, moisturizes, slowly releases and efficiently improves the compliance of the body, and 3) the gel is good in antibacterial and anti-inflammatory effects, good in biocompatibility, free of irritation and capable of promoting wound healing, and only needs to be smeared on the surface of the wound.
Owner:FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Local external medicine composition for treating alopecia as well as preparation method and application thereof

The invention belongs to the field of medicine preparations, and particularly relates to a local external medicine composition for treating alopecia, the medicine composition comprises at least one active component, and the medicine composition comprises the following components in percentage by weight: 1-10% w / w of minoxidil or salt thereof, 0-50% w / w of propylene glycol, 1-50% w / w of ethanol and 10-50% w / w of C3-C10 ether solvent, the total dosage of the propylene glycol and the ethanol is less than or equal to 50% w / w, and the total dosage of the propylene glycol and the ethanol is less than or equal to 50% w / w. The pharmaceutical composition at least has the following excellent characteristics: good curative effect, high drug solubility, high patient efficiency, quick response, few adverse reactions, low scalp irritation, good stability, easy use, no greasy feeling after use, good drug permeability, high bioavailability, few use times, good patient compliance and the like.
Owner:SOLIPHARMA

Iguratimod preparation and preparation method thereof

The invention relates to an Iguratimod preparation and a preparation method thereof, and belongs to the technical field of medicament preparation, and the preparation method specifically comprises the following steps: S1, treating a cyclodextrin derivative by using a compound enzyme to obtain enzyme-treated cyclodextrin; then carrying out oxidation crosslinking on the cyclodextrin subjected to enzyme treatment to prepare modified cyclodextrin; s2, mixing an iguratimod raw material medicine with a suspending aid, carrying out micronization treatment, then adding into a dispersion medium, and uniformly stirring to obtain an iguratimod suspension; s3, the modified cyclodextrin obtained in the step S1 and the iguratimod suspension obtained in the step S2 are homogenized and mixed, then freeze drying is conducted, and the iguratimod preparation is obtained. Through unique preparation design and optimization process, the dissolving property of the iguratimod is remarkably improved, the dissolution rate and bioavailability of the medicine are improved, the stability of the preparation and the medication convenience of a patient are ensured, and a more reliable and efficient solution is provided for clinical application of the iguratimod.
Owner:ANHUI RUIQI PHARMACEUTICAL CO LTD

Whitening and moisturizing essence as well as preparation process and application thereof

The invention provides whitening and moisturizing essence as well as a preparation process and application thereof, and belongs to the technical field of cosmetics. The essence is prepared from tranexamic acid, nicotinamide, macromolecular hyaluronic acid, micromolecular hyaluronic acid, hexapeptide-2, an althaea rosea flower extract, a rhodiola sachalinensis extract, a glycyrrhiza glabra extract, a coast pine needle extract, a polyhydric alcohol humectant, vegetable fat and the like. Wherein the hollyhock flower extract, the rhodiola sachalinensis extract, the glycyrrhiza glabra extract and the coast pine needle extract are respectively obtained by adopting a special enzymolysis method. The tranexamic acid and the nicotinamide are used for synergistically whitening, the hyaluronic acid, the polyhydric alcohols and the vegetable fat are used for jointly moisturizing, the plant extract is used for enhancing oxidation resistance, whitening and safety, the components are ensured to be uniform and stable through a reasonable preparation process, and the effect of the essence is favorably improved.
Owner:GUANGZHOU ZHUANGZE BIO TECH CO LTD

Toothpaste for whitening and removing halitosis and preparation method thereof

The invention provides whitening and halitosis removing toothpaste and a preparation method thereof. The toothpaste is prepared from, by mass, 20%-30% of hydrated silica, 2%-4% of pyrophosphate, 20%-30% of clove powder, 20%-30% of sodium phytate, 0.5%-1.5% of a thickening agent, 20%-30% of hydroxyapatite, 2%-4% of modified glycerin, 2%-4% of a humectant, 20%-30% of sodium tripolyphosphate, 0.1%-0.2% of a bacteriostatic agent, 0.1%-0.2% of a sweetening agent, 2%-4% of a stain remover, 1.0%-2.0% of a foaming agent, 1.0%-1.5% of a preservative and the balance deionized water. Compared with the prior art, the toothpaste composition with the whitening function, disclosed by the invention, has the advantages that by adding the biological enzyme for decomposing pigments and carbohydrates remained in an oral cavity or teeth to generate hydrogen peroxide with a bleaching function, not only can pigments causing exogenous stains of the teeth be removed, but also endogenous stains can be removed; meanwhile, the stimulation to the oral cavity is reduced, and the clove has the effect of removing halitosis because the fragrance of the clove is strong, so that the clove can be used for treating oral diseases and eliminating the odor in the oral cavity.
Owner:GUANGZHOU MINGLI DAILY CHEM CO LTD

Cannabis sativa paste capable of improving constipation and process

The fructus cannabis paste comprises the following raw materials in parts by weight: 120 to 180 parts of fructus perillae, 280 to 320 parts of wheat, 200 to 240 parts of bulbus lilii, 125 to 175 parts of rhizoma dioscoreae, 50 to 100 parts of pericarpium citri reticulatae, 280 to 320 parts of fructus cannabis, 80 to 120 parts of semen armeniacae amarae, 180 to 220 parts of semen persicae, 180 to 220 parts of semen pruni, 180 to 220 parts of semen raphani, 30 to 40 parts of dried figs, 40 to 50 parts of pears and 25 to 35 parts of mulberries. The food has the advantages of quick effect and eating safety.
Owner:HANGZHOU FANGHUICHUNTANG HEALTH TECH CO LTD

Crushing device for chili processing

The utility model discloses a smashing device for pepper processing, and particularly relates to the technical field of smashing devices.The smashing device comprises an operation frame, a feeding hopper device is fixedly connected to the right side of the upper surface of the operation frame, a motor is fixedly connected to the upper portion of the feeding hopper device, and a transmission mechanism is fixedly connected to the outer surface of the output end of the motor; the output end of the motor is fixedly connected with a crushing mechanism, the lower portion of the transmission mechanism is fixedly connected with a rotating mechanism, the outer surface of the crushing mechanism is fixedly connected with a stirring mechanism, and the lower portion of the stirring mechanism is fixedly connected with a collecting device. According to the smashing device for processing the chilies, the shifting mechanism is matched with the smashing mechanism, the chilies automatically fall into the collecting device after being smashed, meanwhile, the smashed chilies which do not meet the requirement are automatically collected and conveyed into the smashing mechanism through matching of the negative pressure device and the screen, the screening time is greatly shortened, and the screening efficiency is improved. The production efficiency is improved, and meanwhile, the granularity consistency and the quality stability of crushed chilies are improved.
Owner:QINGDAO DESHENG HENGXIN FOOD CO LTD