113 results about "Hearing loss" patented technology

The invention relates to a method for testing a participant's ability to accurately detect speech under background noise, comprising: (a) audibly presenting a series of 2-bit numbers, 3-bit numbers, 4-bit numbers and / or 5-bit numbers in a random or fixed order to a participant's first ear at a fixed or varying signal-to-noise ratio (SNR) in a quiet or noisy environment, (b) audibly presenting a series of 2-bit numbers, 3-bit numbers, 4-bit numbers and / or 5-bit numbers in a random or fixed order to the second ear of the participant at a fixed or random signal-to-noise ratio (SNR) in a quiet or noisy environment, where the numbers are presented in the native language of the participant or the fluent language of the participant, (c) recording the numbers or sequence of numbers correctly recognized by the participant, and (c) storing the recorded numbers or sequence of numbers at the second ear of the participant. And (d) calculating a score as a function of the percentage of the number or sequence of numbers correctly replicated by the subject, or as a function of the sound intensity difference between the speech and noise required to achieve the correct recognition of 50% sequence of numbers. The invention also relates to a device and a method for measuring the digital recognition capability related to hearing loss, and to a computer-implemented method for evaluating the speech recognition capability of a participant.

The invention is suitable for the technical field of intelligent equipment, and provides a hearing loss risk assessment method and system, intelligent equipment and a storage medium, and the method comprises the steps: a near-ear wearable device collects an audio signal through a configured acoustic sensor, carries out the sound source classification marking of the audio signal based on a current working mode, and carries out the sound source classification marking of the audio signal; and according to a set time interval or a trigger condition, counting a signal intensity mean value of each sound source type audio signal, sending a sound source classification mark and the counted signal intensity mean value to a cloud server corresponding to the user, and indicating the cloud server to carry out hearing loss risk assessment on the user according to the sound source classification mark and the counted signal intensity mean value. The hearing loss risk assessment method and device can effectively improve the convenience, accuracy and universality of hearing loss risk assessment.

A method and apparatus to assist people with hearing loss. An augmented reality device with microphones and a display captures speech of a person talking to the wearer of the device and displays real-time captions in the wearer's field of view, while optionally not captioning the wearer's own speech. The microphone system in this apparatus inverts the use of microphones in augmented reality devices by analyzing and processing environmental sounds while ignoring the wearer's own voice.

The present disclosure provides preventing and / or treating hearing loss in an individual in need thereof comprising administering a composition comprising one or more viral vectors comprising a nucleic acid encoding COL18A1 protein, SPARC protein, and IGFBP2 protein. The present disclosure also provides method for preventing and / or treating hearing loss in an individual in need thereof comprising administering an effective amount of COL18A1, SPARC, and IGFBP2 proteins to the inner ear of the individual.

The present invention provides a means and a system for screening agents for treating or preventing age-related hearing loss. Specifically, the present invention provides an agent for treating or preventing age-related hearing loss, the agent being characterized by containing, as an active ingredient, at least one compound selected from the group consisting of tea polyphenols and salts and hydrates thereof.

A system and associated processes include a left and right eyewear stem, each including a microphone array comprising a plurality of microphones, and a digital hearing aid that receives content from the microphone array and extracts a desired signal from the content, the digital hearing aid applying frequency-dependent gain to the desired signal to compensate for a user's hearing loss profile. The system further includes processes that receive the desired signal modified with the frequency-dependent gains to acoustically render the desired modified signal proximate to the ear of the user without anything physical being placed within an entrance to an ear canal. A rechargeable battery may be included, along with a front face of the eyewear configured to hold a pair of eyewear lenses, where the front face lacks an electrical conductor connecting the right and left eyewear stem.

Various sounds are reproduced in a passenger cabin of a transportation vehicle with a plurality of positions for seating respective persons who may have differential hearing losses between a right ear and a left ear. A dominant ear and a nondominant ear are identified of a particular user in a respective seating position. Electrical audio signals are generated in a sound source intended for reproduction by an array of speakers disposed within the passenger cabin for directing reproduced sounds toward the seating positions from respective directions. The audio signals are differentially adjusted before sending them to the array of speakers such that reproduced sounds directed to the nondominant ear are attenuated in relation to the reproduced sounds directed to the dominant ear (i.e., the sound to the dominant ear is enhanced).

The utility model discloses a five-axis automatic online sampling device, which belongs to the technical field of electrolytic aluminum electrode carbon block sampling and comprises a control cabinet, a cantilever is arranged at the top of one side of the control cabinet, and a cross beam is arranged on one side of the top of the cantilever; through the sample drilling assembly, the cut-off assembly and the clamping assembly, operation of sample drilling, cut-off, detection of the surface height of a carbon block, clamping of a sample rod and storage of the sample rod can be automatically completed, high automation is achieved, and compared with a traditional manual sampling mode, the sampling time is greatly shortened, the production efficiency is improved, and the production cost is reduced. Meanwhile, workers are liberated from heavy physical labor through automatic operation, only equipment monitoring and simple operation instruction input need to be carried out, workers are prevented from directly making contact with dust and noise sources, the risks that the workers suffer from pneumoconiosis, hearing loss and even deafness are effectively avoided, a healthier working environment is provided for the workers, and the working efficiency is improved. And the cost and risk of enterprises in the aspect of preventing and treating occupational diseases are also reduced.

A hearing aid device is provided that has a body housing a microphone electrically connected to an amplifier. A receiver, in communication with the amplifier, receives an electrical signal converted from sound. A unique feature of the device is the inclusion of a dome, designed to contact within the ear, which is removably attachable to the receiver via a threaded connection mechanism. This mechanism can either be a direct male threaded attachment on the receiver that engages with a female thread within the dome or incorporate a dome insert with the female thread. The dome, typically bell-shaped, mushroom-shaped or umbrella shaped with a size range from 4 millimeters to 12 millimeters depending on individual comfort level and hearing loss, and formed of silicone or a similar material that offer flexibility, durability, and a good formability, can be efficiently detached by twisting between one to six rotations, facilitating easy cleaning or replacement. Made from material that's easily cleaned by a soft cloth, the dome ensures clarity in sound delivery and optimal hygiene for the user.

This utility model discloses a low-noise centrifugal pump for petrochemical applications, comprising a centrifugal pump body, an impeller movably mounted inside the pump body with an impeller shaft mounted on it, an inlet pipe at the front of the pump body, a drain pipe at the top of the pump body, and a low-noise mechanism wrapped around the outside of the pump body. The low-noise mechanism consists of noise reduction covers A, B, C, and D. Noise reduction cover B is fixedly mounted at one end of noise reduction cover A, and noise reduction cover D is fixedly mounted at one end of noise reduction cover C. This low-noise centrifugal pump for petrochemical applications features modularly designed noise reduction covers that can be quickly installed using a mounting bracket without complex tools or specialized skills, reducing the noise level generated by the centrifugal pump and preventing damage to the inner ear hair cells of factory workers, thus avoiding irreversible hearing loss. The rock wool itself has a porous fiber structure, primarily absorbing mid-to-high frequency noise.

The present disclosure provides constructs comprising a coding sequence operably linked to a promoter, wherein the coding sequence encodes a polypeptide (e.g., a therapeutic polypeptide). Exemplary constructs include AAV constructs. Also provided are methods of using disclosed constructs for the treatment of hearing loss and / or deafness.

A hearing device includes: an input module for provision of an input signal; a time domain filter configured to perform filtering to provide a filter output signal based on the input signal; a processor configured to provide an electrical output signal based on the filter output signal, the processor configured to compensate for hearing loss of a user of the hearing device; a receiver configured to provide an audio output signal based on the electrical output signal; and a controller comprising a machine learning model for provision of a model output based on the input signal, wherein the controller is configured to: determine a first gain based on the model output; determine a filter control signal based on the first gain; and provide the filter control signal to the time domain filter for filtering the input signal based on the filter control signal.

1. The name of the design product: hearing aid (FT-20-FT-21). 2. The use of the design product: the design product is used for compensating hearing for air conduction hearing loss patients. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

The present disclosure provides constructs comprising a coding sequence operably linked to a promoter which expresses the polynucleotide in an outer hair cell, wherein the coding sequence encodes a polypeptide (e.g., a heterologous polypeptide). Exemplary constructs include AAV constructs. Also provided are methods of using disclosed constructs for the treatment of hearing loss and / or deafness.

A method of processing audio, the method comprising: receiving audio data for playback on a playback device, the audio data comprising a target audio component; receiving masked audio data; obtaining hearing loss data associated with a listener; obtaining back discharge level data; calculating a target excitation pattern based on the target audio component and the return discharge level data; calculating a masked excitation pattern based on the masked audio data; calculating a signal gain based on the target excitation pattern, the masked excitation pattern, and the hearing loss data; and applying the signal gain to the target audio component to produce a compensated target audio component.

A method and apparatus to assist people with hearing loss. An augmented reality device with microphones and a display captured speech of a person talking to the wearer of the device and displays real-time captions in the wearer's field of view, while optionally not captioning the wearer's own speech. The microphone system in this apparatus inverts the use of microphones in an augmented reality device by analyzing and processing environmental sounds while ignoring the wearer's own voice.

The invention discloses an HSP70-targeting chimeric antigen receptor-macrophage and application thereof in treatment of noise-induced hearing loss, an extracellular domain of the HSP70-targeting chimeric antigen receptor comprises an HSP70 specific binding fragment, an intracellular domain comprises an IL-4 signal channel functional element, a signal switch type CAR structure of the HSP70 is formed, and the macrophage can be used for treating noise-induced hearing loss, so that the HSP70-targeting chimeric antigen receptor-macrophage can be used for treating noise-induced hearing loss. The HSP70-targeted chimeric antigen receptor-macrophage can be used for preparing the HSP70-targeted chimeric antigen receptor-macrophage, is used for mediating polarization of the macrophage to an M2 type and exerting an anti-inflammatory function, is proved to be capable of specifically responding to an inner ear inflammation microenvironment, switching an anti-inflammatory phenotype and protecting hair cells and auditory nerves, can be used for treating noise-induced hearing loss, and can be used for preparing the HSP70-targeted chimeric antigen receptor-macrophage. The limitation that traditional hearing-aid equipment supports treatment on symptoms is broken through, and the hearing-aid device has a remarkable application prospect.

The invention discloses application of NSD2 in cochlea hair cell function maintenance and hearing treatment. Specifically, the invention provides application of an NSD2 gene, mRNA, protein or an expression promoting agent thereof, the NSD2 gene, the mRNA, the protein or the expression promoting agent is used for preparing a preparation or a composition, and the preparation or the composition is used for preventing and / or treating hearing loss. The preparation or the composition is high in pertinence, small in side effect and capable of effectively treating hearing loss.

The present invention provides derivatives of quinolylnitrones of formula I, wherein the meaning of the substituents is as described in the description, useful in treatment and / or prevention of hearing loss.Advantageously, these quinolylnitrones of formula (I) have a broad-spectrum effect, being efficient in the prevention and treatment of hearing loss regardless of its origin, whether caused by a physical agent, such as noise, or an ototoxic agent such as H2O2.

The application relates to the technical field of user behavior analysis, and discloses a hearing aid use behavior analysis system based on multi-dimensional time sequence characteristics, which comprises a time alignment module, parameter channel data, environment channel data and behavior channel data are acquired, the data are sorted according to server time alignment to form multi-channel time sequence data, asynchronous acquisition is continuously represented on the same time axis, a feature statistical module is used for calculating short-term features of statistical quantities in a preset time window, long-term features of wearing time and average hearing aid power are statistically calculated according to natural days, the features are combined to form a multi-dimensional time sequence feature sequence, scene and operation changes are stably described, a channel modeling module is driven by the sequence to form a multi-channel time sequence model, user behavior feature representation and hearing loss trend prediction results are output, the short-term fluctuation and the long-term evolution are connected, a behavior clustering module is used for clustering to form a user behavior portrait according to the representation, and individualized test and fitting suggestions are generated in combination with the hearing loss trend prediction results and the parameter channel data.

An audio system includes one or more acoustic sensors capturing audio from a local area surrounding the audio system and one or more additional sensors capturing data describing the local area. An audio controller in the audio system identifies interactions by a user based on the captured audio and the data describing the local area. The audio controller determines attributes associated with each interaction, such as metrics describing speaking by the user, metrics describing requests for clarification by the user, and metrics based on a topic determined from audio captured by the user. Based on the interactions and associated attributes, the audio controller estimates a sound profile for the user that identifies ranges of frequencies where the user has hearing loss. The audio controller may leverage the sound profile to determine one or more filters to offset hearing loss of the user.

The invention discloses a hearing aid and spoken language partner training integration method and system based on hearing loss and compensation, and belongs to the crossing field of hearing aid and artificial intelligence language learning. The method is cooperatively executed by a Bluetooth headset and a mobile terminal application program, and comprises the following steps: establishing a personalized hearing loss curve of a user; the equipment has an intelligent hearing aid mode and a spoken language partner training mode. And in the hearing aid mode, real-time compensation playing is carried out on the environment sound based on the curve. In the partner training mode, three partner training processes of real-time, preset scene and word generation scene are provided, and adaptation processing is performed on the generated partner training audio based on the same hearing curve, so that key teaching phonemes are ensured to be clear and audible. The core innovation lies in that the system dynamically adjusts the compensation parameter of the hearing loss curve by analyzing the pronunciation accuracy of the user in partner training, and realizes collaborative optimization and personalized improvement of the hearing aid effect and the spoken language ability.

The invention relates to the technical field of nano medicines, and discloses an ATP / cerium coordination polymer nano regulator as well as a preparation method and application thereof. The invention relates to an ATP / cerium coordination polymer nano regulator. The invention relates to a self-assembly hydrogel which is prepared from raw materials including cerous nitrate (III), adenosine-5 '-disodium triphosphate, phospholipid polyethylene glycol amino, SS31 peptide and a diselenide cross-linking agent through a self-assembly and cross-linking method, can effectively remove ROS (reactive oxygen species) in an inner ear and protect cells from oxidative stress injury, thereby protecting auditory cells and improving the quality of the inner ear. The traditional Chinese medicine composition has the effect of treating hearing loss caused by oxidative stress induced by noise, can be used for treating hearing loss through middle ear cavity local administration, is simple in preparation method and mild in reaction condition, and can realize large-scale production. Cascade catalysis of cerium (III) and cerium (IV), ATP (adenosine triphosphate) energy supply and a nano system of a selenium biological material are utilized, and a novel method is provided for treating noise-induced hearing loss.

A hearing-assistive device-based hearing loss compensation method is performed by the terminal. A communication connection is established between the terminal and a hearing-assistive device to be fitted. The method includes: performing a hearing loss test on a hearing-assistive object to obtain a hearing loss test result; performing hearing loss compensation based on the hearing loss test result to obtain a hearing loss compensation gain; and sending the hearing loss compensation gain to the hearing-assistive device, where the hearing-assistive device is configured to perform hearing loss compensation on a first speech signal based on the hearing loss compensation gain to obtain a second speech signal.

The utility model relates to an intelligent medicine box with a reminding function, and belongs to the technical field of intelligent medicine boxes. An intelligent medicine box with a reminding function comprises a lower shell provided with a plurality of medicine storage grids; the upper shell covers the lower shell, and a medicine taking opening is formed in the upper shell; the driving assembly is arranged on the upper shell, and the driving assembly can drive the medicine taking opening to do reciprocating translation in the first direction or the second direction relative to the upper shell, so that the medicine taking opening is opposite to at least one medicine storage grid; and the loudspeaker is arranged on the upper shell. The driving assembly drives the medicine taking opening to do reciprocating translation, so that the medicine taking opening is aligned with different medicine storage grids, a user can take specified medicine conveniently, and operation is easy and convenient. The loudspeaker is mainly used for reminding the old to take medicine on time through sound signals. Compared with a traditional alarm clock or mobile phone reminding mode, the voice reminding mode is more direct and effective, and especially for the elderly with hearing loss, the risk that medicine is missed to be taken can be remarkably reduced.

System and techniques for identifying and applying personalized audio processing parameter settings for a listener with hearing loss and / or certain listening preferences. The listener creates and allows for automatic recall of a first profile representing a set of audio enhancement processing parameters associated with the listener as well as create and recall a source-dependent profile representing a further improvement, or deviation, from the first profile associated with a source signal or a category of source signals, such as the voice of a given talker.

Disclosed herein are methods for treating and / or preventing AG-induced hearing loss. The methods involve downmodulating GABARAP disclosed herein to thereby treat and / or prevent AG-induced hearing loss. Also disclosed herein are methods for treating and / or preventing AG-induced hearing loss in a patient in need thereof comprising downmodulating GABARAP, disclosed herein, to thereby treat and / or prevent AG-induced hearing loss in a patient in need thereof.

Aspects of the disclosure relate to compositions, nucleic acids, vectors, viruses, and methods useful for treating hearing loss and / or blindness, for example, Usher Syndrome type IF. The present disclosure provides isolated nucleic acids, vectors, and rAAV.9.PHP.B comprising a transgene encoding a mini-PCDH15, and methods of treating hearing loss using the same. The present disclosure also provides a gRNA associated with a base editor to correct one or more mutations in PCDH15 for treating hearing loss and / or vision loss.

The application discloses a hearing aid and oral language practice integrated method and system based on hearing loss and compensation, and belongs to the cross field of hearing aid and artificial intelligence language learning. The method is cooperatively executed by a Bluetooth earphone and a mobile terminal application program, and comprises the following steps: a user's personalized hearing loss curve is established; the device has a dual mode of intelligent hearing aid and oral language practice. In the hearing aid mode, the environment sound is compensated and played in real time based on the curve. In the practice mode, three practice processes of real-time, preset scene and new word scene are provided, and the generated practice audio is adaptively processed based on the same hearing curve, so that the key teaching phonemes are clear and audible. The core innovation is that the system dynamically adjusts the compensation parameters of the hearing loss curve by analyzing the pronunciation accuracy of the user in the practice, so that the hearing aid effect and oral language ability are cooperatively optimized and individually improved.