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52 results about "Eardrum" patented technology

In the anatomy of humans and various other tetrapods, the eardrum, also called the tympanic membrane or myringa, is a thin, cone-shaped membrane that separates the external ear from the middle ear. Its function is to transmit sound from the air to the ossicles inside the middle ear, and then to the oval window in the fluid-filled cochlea. Hence, it ultimately converts and amplifies vibration in air to vibration in fluid. The malleus bone bridges the gap between the eardrum and the other ossicles.

Method and system for obtaining three-dimensional ear mold model and storage medium

The invention relates to the technical field of image processing, in particular to an ear mold three-dimensional model obtaining method and system and a storage medium. The method comprises the following steps: if acquisition parameters of an acquisition probe are lower than a preset acquisition parameter threshold value, controlling the acquisition probe to be inserted into an auditory meatus inlet, and acquiring an auricular conchae image; utilizing the auricular conchae image to identify the contour boundary of the auricular conchae, generating an entrance reference surface, and determining a auricular return fitting point; identifying an external auditory canal area according to the conchae contour boundary, collecting an external auditory canal image, extracting an auditory canal center line, measuring the sectional dimension, and constructing an eardrum curved surface; and performing hole repairing on the eardrum curved surface, performing smoothing processing, verifying the rationality of the eardrum structure, and exporting a standard three-dimensional eardrum file. According to the invention, the automatic generation of the standard three-dimensional ear mold is realized based on the image processing technology, and the ear mold reconstruction precision and the matching rate are improved.
Owner:HUIZHOU HONGXUANHE TECH CO LTD

Self-adaptive noise reduction and health early warning integrated system based on auditory meatus physiological features

PendingCN121792908AEar treatmentAlarmsAural pressureFrequency spectrum
The invention relates to the technical field of earphone noise reduction, in particular to a self-adaptive noise reduction and health early warning integrated system based on auditory meatus physiological characteristics, and adopts the technical scheme that a multi-mode sensor array is integrated on the inner side of an earphone earplug; distance data in different directions of the auditory meatus and microenvironment data in the auditory meatus are collected, the contact pressure between an earplug and the auditory meatus wall is detected, the adaptability of a noise reduction individual is enhanced, model parameters are updated in modeling logic of the collected data, and the problem of adaptation failure caused by model fixation is avoided; aNC parameters are subjected to two-dimensional optimization based on the auditory meatus physiological model and the environmental noise spectrum, leakage of low-frequency noise is made up, ear pressure swelling pain is avoided, stimulation of high-pressure signals to the tympanic membrane is reduced, a frequency response curve is dynamically adjusted on the basis of adaptive parameters of the auditory meatus model, and the noise reduction effect and comfort level balance are achieved; closed-loop linkage of ear canal features, noise reduction parameters and health states is achieved through a health risk identification logic and linkage protection measure combined algorithm, and the problem that health monitoring and noise reduction linkage is lacked is solved.
Owner:陵水安声科技有限公司

Signal transmission device; Electronic device; Method for reversibly connecting an electronic device; Method for changing different devices

A signal transmission device, an electronic device, a method for reversibly connecting an electronic device, and a method for changing different devices are proposed, in which, in particular, a conducted (e.g., wired) loudspeaker, especially a piezo loudspeaker (2), which is attached to the eardrum (3) and excites it to vibrate, is used, wherein the ear canal (4) generally remains open and the natural acoustic transparency of the outer ear is maintained, since the signal transmission from the electronic device to the loudspeaker and the necessary otoplastic measures are generally placed at least partially outside the ear canal (4).
Owner:BOCK FRIEDRICH

Real ear sound pressure level measurement for a hearing device

Disclosed herein, among other things, are systems and methods for sound pressure level measurement for hearing devices. Various aspects include a method for sound pressure level measurement using self-mixing interferometry. The method includes directing a coherent light signal towards an eardrum of a user using an optical generation device, directing an audio signal towards the eardrum of the user using an audio generation device, and sensing a reflected light signal from the eardrum of the user using an optical sensor device. Displacement of the eardrum caused by the audio signal is computed using the reflected light signal, and real ear sound pressure level (SPL) at the eardrum is computed based on the displacement of the eardrum.
Owner:STARKEY LABORATORIES INC

Earbud with a built-in thermometer

An earbud includes a housing, a thermometer module and a speaker module. The housing defines a passageway having a passageway opening. The thermometer module is disposed in the housing, and receives infrared radiation from an eardrum via the passageway. The speaker module is disposed in the housing, and is operable to generate sound waves that travel through the passageway toward the eardrum. The speaker module cooperates with the housing and the thermometer module to define an infrared radiation path and a sound wave path within the passageway that are separated from each other and that are for the infrared radiation from the eardrum and the sound waves generated by the speaker module to respectively travel therethrough.
Owner:PRECISION SENSORS DESIGN INC +1

Acoustic processing device

The present disclosure relates to an acoustic processing device that can suppress the occurrence of excessive atmospheric pressure changes in the eardrums of a user. Provided is an acoustic processing device comprising: a driver unit having a diaphragm; and a housing in which the driver unit is housed. The diaphragm has a vent hole that communicates a first space on a first surface side of the driver unit in the housing and a second space on a second surface side on the reverse side of the first surface. The present disclosure can be applied to, for example, an earphone device.
Owner:SONY GROUP CORP

Ear drum lesion area segmentation system based on ear canal endoscope image

InactiveCN121661073AImage enhancementImage analysisComputer visionCholangioma
The invention relates to the technical field of region segmentation, in particular to an ear drum lesion region segmentation system based on an ear canal endoscope image. According to shape features of different connected domains in a lesion area and gray level distribution of pixel points, noise connected domains are screened out; taking other connected domains except the noise connected domain as target connected domains, and obtaining the gray dispersion of each target connected domain according to the gray distribution of the pixel points in each target connected domain; according to the gray dispersion of the different target connected domains, obtaining a cholanoma connected domain cluster and a calcification spot connected domain cluster; and according to the position distribution of the connected domains between the cholangioma connected domain cluster and the calcification spot connected domain cluster and the gray level distribution of the pixel points in the calcification spot connected domain under different frames, obtaining an overlapping region between the calcification spot connected domain cluster and the cholangioma connected domain cluster, and carrying out region segmentation. According to the invention, the accuracy of region segmentation is improved by accurately identifying the overlapped region of the calcified spot on the lipoma.
Owner:YANAN UNIV AFFILIATED HOSPITAL

Glasses leg system and intelligent glasses

The utility model belongs to the technical field of intelligent wearable equipment, and discloses a glasses leg system and intelligent glasses, and the glasses leg system comprises glasses legs, a loudspeaker assembly and a covering assembly. The loudspeaker assembly is provided with a first sound outlet hole and a second sound outlet hole, and the loudspeaker assembly is adjustably connected to the glasses legs and has a first position and a second position relative to the glasses legs; when the loudspeaker assembly is located at the first position, the extension direction of the loudspeaker assembly is the same as that of the glasses legs; when the loudspeaker assembly is located at the second position, an included angle is formed between the loudspeaker assembly and the glasses leg, and the second sound hole faces the external auditory canal of the ear; the covering assembly is slidably connected to the loudspeaker assembly, and the covering assembly is provided with a covering position for covering the first sound outlet hole and an exposing position for exposing the first sound outlet hole. The glasses leg system and the intelligent glasses provided by the utility model have relatively high sound effect and sound quality, and have relatively small damage to eardrums.
Owner:LUXSHARE PRECISION TECH(NANJING) CO LTD

Or relating to earpieces

An apparatus for detecting ear structure movements or changes, or changes in pressure in the ear-canal of a user, in order to control or affect the function of an associated device. The apparatus includes a sensor apparatus capable of being worn by the user to be located in or adjacent an ear-canal of the user. The sensor apparatus includes at least one sensor being located and configured to detect and capture sensor data relating to middle ear, ear-drum complex, ear-drum margin, and / or other ear structure movements or changes of characteristics, or changes in pressure in the ear-canal of the user. A device is provided for processing and analysing sensor data from the sensor apparatus. The device analyses sensor data concerning: eye movement or directional auditory attention or focus data, and / or voluntary control data.
Owner:EARSWITCH LTD

Automatic filling device for drag reducer for fracturing

The utility model relates to the technical field of filling devices, in particular to an automatic filling device for a drag reducer for fracturing, which comprises a cart and a tank body, a pump is assembled on one side of the tank body, the output end of the pump is connected with a water inlet pipe, and a pressure control mechanism connected with a pipeline is arranged at one end of the water inlet pipe. A water inlet pipe connected with the pipeline is arranged at one end of the connecting cylinder, a water outlet pipe connected with the pipeline is arranged at one end of the pressure control mechanism, and the pressure control mechanism is arranged to control the dosage of the drag reducer passing through the water outlet pipe by the water inlet pipe according to the pressure of fluid passing through the pipeline. Friction resistance of fluid passing through the pipeline is increased, pressure borne by the tympanic membrane is also increased, when the tympanic membrane deforms, the connecting block, the connecting rod and the piston are driven to slide, dosage adjustment of the drag reducer through the through hole is achieved, manual adjustment of workers is not needed, and the working difficulty of the workers is reduced.
Owner:SICHUAN YIXUAN HENGJIN ENERGY TECHNOLOGY CO LTD

Audio playing method, electronic equipment and computer readable storage medium

The invention provides an audio playing method, electronic equipment and a computer readable storage medium. The audio playing method comprises the steps that ear size information of a user is acquired, the ear size information comprises a first distance between an auricle and an eardrum, and the first distance is determined according to first detection information obtained when the ear of the user is detected by a radar; acquiring head size information of the user; determining a first parameter of a head-related transfer function according to the first distance and the head size information; and processing the audio according to the head-related transfer function of which the parameter is the first parameter, and playing the processed audio. The first distance between the auricle and the eardrum of the user is obtained through the first detection information of the radar, and the matching degree of the obtained first parameter of the head-related transfer function and the human body characteristics of the user is improved, so that the sound reflection condition of the ears of the user can be simulated more accurately, and then the audio is processed according to the head-related transfer function, and the user experience is improved. The audio processing precision can be improved, and the auditory experience of a user can be improved.
Owner:HONOR DEVICE CO LTD

Ear system with adaptable structure

PCT designated stageWO2025252613A1MicrophonesLoudspeakersEngineeringAudiology
An ear system having at least one main component which can be positioned in a person's ear canal, said main component having a core and an adaptable structure, the adaptable structure being arranged on the core in connection therewith and being configured for adaptation to a surface of the person's ear canal and / or eardrum in a location in which the main component can be properly positioned.
Owner:VIBROSONIC GMBH

An ear thermometer with a low thermal conductivity probe

The application discloses an ear thermometer with a low-thermal-conductivity probe and relates to the technical field of ear thermometers. The ear thermometer comprises an ear thermometer main body, a temperature measuring probe and a first flexible layer. The temperature measuring probe is arranged at the front end of the ear thermometer main body and is used for detecting the temperature of an eardrum. The first flexible layer covers at least part of the outer surface of the temperature measuring probe, and the thermal conductivity coefficient of the first flexible layer is lower than a set thermal conductivity threshold. When the temperature measuring probe detects the temperature inside an ear canal, the first flexible layer is in contact with the ear canal. The ear thermometer provided by the application greatly reduces the ear temperature measurement error caused by the cooling effect of the ear canal, and ensures the accuracy and reliability of temperature measurement of the ear thermometer. In addition, the soft texture of the first flexible layer provides a more comfortable skin contact feeling and reduces the discomfort possibly caused by the hard material.
Owner:SHENZHEN FINICARE CO LTD

Headphone with reflection sound cone

The utility model discloses a headphone with a reflection sound cone, which comprises a headband and earmuff assemblies connected to two ends of the headband, each earmuff assembly comprises an earphone main body and a sounding unit, each sounding unit comprises a loudspeaker front cavity support, a woofer, a PCBA mainboard and a loudspeaker rear cavity support, the woofer is arranged between the loudspeaker front cavity support and the loudspeaker rear cavity support, and the reflection sound cone is arranged between the loudspeaker front cavity support and the loudspeaker rear cavity support. The PCBA main board is arranged on the loudspeaker rear cavity support, a reflection sound cone is arranged in the center of the inner side of the loudspeaker front cavity support, the reflection sound cone and the woofer are coaxially arranged, and the reflection sound cone extends and protrudes towards the direction of the woofer. According to the headphone with the reflection sound cone provided by the utility model, sound waves emitted from the woofer are radiated by 360 degrees in all directions through the reflection sound cone, so that the sound waves entering the auditory meatus are diffused from the center to the periphery, the direct impact of the sound waves on eardrums is reduced, and a user can listen to sound more softly.
Owner:SHENZHEN MENGQU LIFE TECH CO LTD

Moving iron loudspeaker structure capable of reducing tympanic membrane pressure

ActiveCN223528215UElectrical transducersMoving iron speakerSound quality
A moving iron loudspeaker structure capable of reducing tympanic membrane pressure comprises an outer cover assembly, a sound output assembly, a driving assembly and a vibration assembly. The outer cover assembly comprises a rear cavity cover, a rear cavity hole is formed in the bottom of the rear cavity cover, a front cavity cover is assembled on the rear cavity cover, and a through opening is formed in the front end of the front cavity cover. The sound output assembly is arranged at one end of the outer cover assembly and comprises a sound output nozzle, and sound is output from the sound output nozzle through the through opening. The vibration assembly is arranged in the front cavity cover and comprises a vibrating diaphragm, and a vibrating diaphragm hole is further formed in the vibrating diaphragm. The driving assembly is arranged in the rear cavity cover and used for driving the vibrating diaphragm to vibrate. The earphone can reduce the pressure of the earphone on the tympanic membrane when a user wears the earphone, and improves the sound quality.
Owner:CHENGDU SOFT EAR ACOUSTICS TECH CO LTD

Detachable ear canal component

PCT designated stageWO2025252893A1Completely in canal hearing aidsIn the ear hearing aidsAuditory systemAudiology
The present invention relates to a hearing system having an eardrum component for positioning on a user's eardrum and an ear canal component for positioning in the user's ear canal, the ear canal component and the eardrum component being connected to one another for the transfer of energy and / or information in such configuration that the ear canal component can be removed from the ear canal without the eardrum component also being removed.
Owner:VIBROSONIC GMBH

Probe tube

ActiveJP2026005436AAudiometeringDeaf-aid setsMedicineReal ear measurement
To arrange a tip part at a desired position when measuring an actual ear.SOLUTION: The probe tube 1 has a distal end portion 11 that is disposed in the vicinity of the eardrum during measurement, and a curved portion 12 that is disposed slightly on the proximal end portion 13 side from the distal end portion 11 so as to follow the curved shape in the ear canal.SELECTED DRAWING: Figure 1
Owner:VERNAL BROTHERS CO LTD

Support for ear canal component or eardrum component

The present invention relates to an ear system for arrangement in a user's ear, comprising at least a first main component and at least a second main component, wherein the second main component is arranged on the first main component such that, when the ear system is arranged as intended in the user's ear, the second main component supports the first main component against a fixed point, against an inner surface of the ear canal and / or against a further first main component.
Owner:VIBROSONIC GMBH

Earphone

[Problem] The objective is to provide an earphone which allows a driver to be disposed close to a mesh member, with improved fit for the user when an ear tip body section is fitted into the external auditory canal. [Solution] The earphone comprises: an earphone body section 15 having an external auditory canal insertion part 32 to be inserted into an external auditory canal 102 of a user; and an ear tip body section 50 to be inserted into the external auditory canal. The earphone body section includes a driver 35 provided in an internal space of the external auditory canal insertion part. The ear tip body section includes: a first mesh member 57 located on the user eardrum side of the external auditory canal insertion part; and an ear tip part 60 comprising a fixed part 61 formed on the outer peripheral side of the first mesh member, a connected part 71 detachably connected to the outer peripheral part of the external auditory canal insertion part, and an outer peripheral side annular part 75 located on the outer peripheral side of the fixed part.
Owner:FOSTER ELECTRIC CO LTD

Fully plastic ear pick

PCT designated stageWO2026020524A1Ear treatmentBristlePlastic materials
A fully plastic ear pick, comprising a rod (1), and a first brush head (2) and a second brush head (3) that are arranged at two ends of the rod (1). The first brush head (2) has an elliptical shape. The outer diameter of the first brush head (2) gradually decreases from the end portion away from the rod (1) to the end portion close to the rod (1). Several annular bristle rings (21) are arranged on the first brush head (2). The second brush head (3) is in the shape of a spoon. A bristle layer (33) is arranged on the second brush head (3). The rod (1) is made of PP material. The first brush head (2) and the second brush head (3) are integrally formed by means of TPE double-shot injection molding. Two brush heads with different shapes are arranged at two ends of the rod (1), so that the cleaning function of the ear pick is better fulfilled, and the use efficiency of the ear pick is improved. The ear pick is made of a plastic material, which can enhance the softness of the ear pick, so that the ear pick is more comfortable to use and is prevented from causing damage to the ear canal and eardrum due to being too hard. The present invention prevents the brush head from damaging the eardrum when the brush head is inserted too deeply due to external impact during the use of the ear pick, and increases the area of the hand grip, so that the ear pick is safer to use.
Owner:SHANTOU POLO TECHNOLOGY CO LTD

Ear tag type auditory meatus temperature monitoring device

The invention belongs to the field of clinical contact thermometers of animals, and particularly provides an ear tag type auditory meatus temperature monitoring device. The device comprises an ear tag body, the ear tag body comprises a shell, a controller and a battery are arranged in the shell, a flexible piece is led out of the ear tag body, the flexible piece can deform to be in the state of being matched with the shape of an external auditory canal and is used for being inserted into the external auditory canal, a temperature measuring probe is arranged at the tail end of the flexible piece and electrically connected with the controller, and a clamping arm is arranged at one end of the shell. A clamping space is formed between the clamping arm and the shell, the clamping arm can be opened and closed through elastic deformation and is used for being clamped on the auricle of an animal, one of the clamping arm and the shell is provided with a conical head used for penetrating through the auricle, and the other one of the clamping arm and the shell is provided with a fixing base allowing the conical head to be clamped in. According to the device, the temperature measuring probe can be fixed in the external auditory canal, the eardrum temperature at a relatively constant position can be accurately measured, the temperature measuring and monitoring device is prevented from falling off due to animal movement in cooperation with clamping and fixing of the clamping arm and the shell, and stress reaction of animals is avoided.
Owner:HENAN UNIV OF SCI & TECH

A four-in-one in-ear hearing aid earphone

The application discloses a four-in-one in-ear hearing aid earphone, which comprises two earphones, each of which is provided with a shell; a bone conduction hearing aid device is arranged in the inner cavity of the first side of the shell of each earphone; a loudspeaker sounding device is arranged in the inner cavity of the second side of the shell of each earphone; a control circuit is electrically connected with the bone conduction hearing aid devices and the loudspeaker sounding devices of the two earphones respectively, and is used for controlling the two bone conduction hearing aid devices and the two loudspeaker sounding devices to simultaneously output audio signals input to the control circuit by a sound pickup device. The four sounding units simultaneously conduct sound waves, the hearing aid effect is better, the four-in-one in-ear hearing aid earphone is suitable for people with damage, inflammation or functional degradation of ear canal, eardrum, middle ear or inner ear, and is also suitable for specific people with damage, degradation or tissue lesions of bone tissue such as skull, and is flexible to use, and has better compatibility and universality.
Owner:DAI3MIMI HEALTHTECH LTD

Devices for at-home physical examination of the ear and ear canal

A diagnostic device is configured to capture diagnostic information about a subject (e.g., the subject's ears). The diagnostic device may include a diagnostic extension housing diagnostic elements (e.g., imaging chip, light sources, or lenses) and an ear canal engagement section coupled to the diagnostic extension. The ear canal engagement section may be shaped to position the diagnostic extension superiorly within the ear canal. For example, one side of the ear canal engagement section may be longer than another, which may enable the ear canal engagement section to contact the inferior wall of the ear canal for a longer distance than it contacts the superior wall. This configuration may allow more movement of the diagnostic extension when the device is inserted into the ear, which further improves the alignment of diagnostic elements with a desired area of the car for diagnoses (e.g., the eardrum).
Owner:BOUCHER RYAN

Split external ear drum sound transmission stethoscope

PendingCN121606310AStethoscopeEarpiece/earphone attachmentsExternal earsSTETHOSCOPE HEAD
The invention discloses a split external eardrum sound transmission stethoscope. The split external eardrum sound transmission stethoscope comprises a stethoscope body and external earphones. The stethoscope is of an I-shaped structure and is composed of a handle, a connecting rod and a stethoscope head, a controller, a power source assembly and a detection layer are arranged in the stethoscope, and sound signals can be collected, processed and wirelessly transmitted. The external earphone comprises two earphone heads and an ear clip, and sound is transmitted to an ear drum of a user through signal receiving, conversion and amplification. According to the scheme, the split design is adopted, and the external earphone prevents the auditory meatus from being pressed; a multi-stage signal processing module is integrated, sound collection, noise reduction, amplification and digital transmission are achieved, and it is guaranteed that signals are clear; main and standby power supplies and a wireless charging function are arranged, the endurance reliability is improved, and backtracking analysis is supported; and the wireless transmission and the split structure improve the operation flexibility, are suitable for long-time use, and have the advantages of convenience and digitization of traditional equipment.
Owner:SHENZHEN FUTIAN DISTRICT MATERNAL & CHILD HEALTH HOSPITAL

Photocuring adhesive for forming coated nail film and forming method of photocuring adhesive

The invention relates to the technical field of curing molding, in particular to a photocuring adhesive for coating type nail film molding and a molding method thereof.The molding method comprises the steps that a nail film feature area image is obtained and divided into a colloid area and a blank area, and the actual wrapping degree of the feature area is determined based on the total number of pixels of the colloid area and the blank area; determining the membrane attachment positioning condition; in response to a nail film lamination positioning condition, obtaining colloid characteristic parameters of the photocuring glue in a pre-curing process according to an initial detection period, and determining a real-time deviation rate of pre-curing based on an actual variable quantity of the colloid characteristic parameters; and in response to the curing degree, adjusting the total light energy dose corresponding to the illumination parameters of the pre-curing and the main curing based on the deviation ratio and the correction coefficient, and correcting the initial preset illumination intensity and illumination duration of the pre-curing and the main curing. The light curing parameters are predicted, regulated and controlled according to the colloid characteristic parameters of the light curing glue and the curing degree, and the finished product quality is improved.
Owner:XIAN YIYUN COSMETICS CO LTD

Microphone position adjustment method, device, system and readable storage medium

The application discloses a microphone position adjusting method, device, system and readable storage medium, and the method comprises the following steps: when detecting that the earphone is inserted into the ear, determining a target distance between the microphone and the eardrum of a user; emitting a positioning signal through the loudspeaker, and determining the current position of the microphone according to the time when the microphone receives the positioning signal; and adjusting the current position according to the target distance. According to the application, the target distance between the microphone and the eardrum of a user and the current position of the microphone in the earphone are determined, the current position of the microphone is adjusted according to the target distance, the distance between the microphone and the eardrum of a user is reduced, and the noise reduction performance of the feedback noise reduction earphone is improved.
Owner:GEER TECH CO LTD

Prediction and correction of sound pressure at eardrum

PendingCN121151749AHearing device active noise cancellationEar moulds/tips acoustic sealsOutput deviceAudio frequency
Various embodiments disclose a computer-implemented method that may include driving an audio output device to reproduce a stimulation signal when a wearable device is placed along an ear canal of a user; receiving a sound signal from a microphone based on the stimulation signal; and determining one or more characteristics of the ear canal of the user based on the sound signal and a computational response of the microphone retrieved from a memory, wherein the one or more characteristics of the ear canal include an ear canal impedance; and applying an ear canal response correction to an output signal played by the audio output device based on the one or more characteristics of the ear canal.
Owner:HARMAN INT IND INC

Hearing device

A hearing device is proposed. The invention relates to an ITE part (1) to be placed at least partially in an ear canal, the ITE part (1) comprising: a connector (21) to be coupled to a BTE part to be worn behind a pinna; a hollow ear mold (3) comprising a front end (5), a back end (7) and a hollow cavity (23), the ear mold having the front end (5) facing a user's eardrum during use, the front end (5) comprising a front opening (9), the front opening (9) comprising a front filter (15), the back end (7) comprising a back opening (10), the ITE part (1) further comprising: a receiver (11) arranged in the hollow cavity (23), a sound channel extending between the front opening (9) and the back end (7) and allowing a fluid connection between the front opening (9) and outside the hollow ear mold (3); an active vent (13) comprising a valve, the valve being positioned at the front end (5), the active vent having an open state and a closed state, the valve providing the fluid connection through the sound channel in the open state and hindering the fluid connection through the sound channel in the closed state; a back filter (17) arranged at the back opening or in the hollow cavity and between the back opening and the valve.
Owner:GN HEARING AS

A kind of external use ear drop for promoting auditory nerve growth and its preparation method

The application belongs to the technical field of biological medicine preparation, and particularly relates to an external use ear drop for promoting auditory nerve growth and a preparation method thereof. The composition raw materials comprise the following components: active small molecules, glyceryl stearate, glyceryl monostearate, soybean lecithin, vitamin E succinate, Tween-80, chitosan quaternary ammonium salt, diethylene glycol monoethyl ether, penetration aid, penetrant, sodium cholate, N-acetyl cysteine, F127 surfactant, F68 surfactant and sodium hyaluronate. Through the synergistic effect of the crystalline lipid core, the positive chitosan quaternary ammonium salt shell, the heat-sensitive in-situ gel outer layer and the mild penetration system, the drug is long-acting retained, smoothly released and efficiently penetrated into the inner ear target area under the condition of not puncturing the eardrum, and the synergistic system significantly improves the stability, local exposure and treatment efficiency of the drug.
Owner:顾虹