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84 results about "Local anesthesia" patented technology

Local anesthesia is any technique to induce the absence of sensation in a specific part of the body, generally for the aim of inducing local analgesia, that is, local insensitivity to pain, although other local senses may be affected as well. It allows patients to undergo surgical and dental procedures with reduced pain and distress. In many situations, such as cesarean section, it is safer and therefore superior to general anesthesia. It is also used for relief of non-surgical pain and to enable diagnosis of the cause of some chronic pain conditions. Anesthetists sometimes combine both general and local anesthesia techniques.

RT tube application method for simultaneously solving blockage of upper and lower lacrimal passages

PendingCN120284591AEye surgeryWound drainsPeriocular tissuePeriocular area
The invention relates to the technical field of RT type lacrimal passage drainage tube application, and particularly discloses an RT tube application method for simultaneously solving upper and lower lacrimal passage blockage, which comprises the following steps of: firstly, performing preoperative local anesthesia on a patient; the upper lacrimal punctum and the lower lacrimal punctum of the diseased eye are expanded, and after a thin probe is used for probing the obstruction position of the lacrimal passage from the upper lacrimal ductule and the lower lacrimal ductule, the lacrimal passage is flushed Expanding the obstructed part of the lacrimal passage by using a large probe; then, the artificial lacrimal duct is implanted, the RT tube is implanted into the upper and lower lacrimal ducts at the same time, the problem of blockage of multiple parts is solved through a single instrument, repeated damage to periorbital tissue caused by fractional operations is avoided, and the device is particularly suitable for complex cases that upper and lower lacrimal canalicules and nasolacrimal ducts are blocked or narrow at the same time; the whole-course drainage of the tears from the upper and lower lacrimal passages to the nasal cavity is further ensured, and the physiological path of tear circulation is recovered; the RT tube is placed, skin or mucous membrane does not need to be cut open, no scar is visible after operation, and the requirement for periocular beauty is met.
Owner:HUZHOU AIER EYE HOSPITAL CO LTD

Guided injection for local anesthesia

There is provided a method comprising: detecting and / or segmenting a dental-related anatomical structure of a subject from a dental 3D imaging model, wherein the dental-related anatomical structure includes a target for injection of anesthesia by a dental syringe, accessing sequential frames of an oral cavity of a subject captured by an image sensor during a dental session of the subject, presenting within a GUI, at least one fused frame depicting a merger of the sequential frames and the segmentation of the dental-related anatomical structure of the subject registered to the sequential frames, wherein the dental-related anatomical structure is depicted on the sequential frames at a location indicating the target for injection, and dynamically updating the location of the dental-related anatomical structure depicted on the sequential frames according to dynamic adaptation of a pose of the image sensor.
Owner:MARS DENTAL AI LTD

Soluble microneedle for local anesthesia and local anesthesia patch comprising same

The present invention relates to a soluble microneedle for local anesthesia and a local anesthesia patch comprising same, the soluble microneedle comprising an amide-based local anesthetic, hyaluronic acid, and polyvinylpyrrolidone in a specific content ratio. The present invention uses the soluble microneedle to implement direct drug delivery by physically permeating through the stratum corneum and mucosa, and thus a precise and rapid anesthetic effect may be exhibited. Especially, the microneedle comprising a specific amount of polyvinylpyrrolidone is dissolved, and the anesthetic contained in the microneedle is rapidly delivered to nerve cells, and thus the disadvantage of a long waiting time of conventional anesthetic creams may be overcome, and thus the present invention has the advantage of being usable in various ways in dental, dermatology, and other surgical procedures requiring local anesthesia.
Owner:UI (UNIVERSITY IND FOUNDATION) YONSEI UNIVERSITY +1

Puncture assembly for trigeminal nerve meniscus balloon compression under local anesthesia

InactiveCN120570652ABalloon catheterAnaesthesiaSurgical operationAnesthesia needle
According to the puncture assembly for the trigeminal nerve meniscus balloon compression operation under local anesthesia, firstly, an anesthetic needle is designed to be of a detachable structure and can be arranged in a puncture needle in a sliding and sleeving mode, and precise local anesthesia is conducted firstly in the puncture process; then the same puncture channel is used for carrying out subsequent balloon catheter insertion operation; and secondly, the balloon is fixedly arranged at the front end of the balloon catheter and is connected with the balloon dilatation pressure pump, so that moderate compression on the trigeminal nerve meniscus can be realized by accurately controlling the filling degree of the balloon in the operation process. Meanwhile, the pressure pump has a real-time monitoring function on the internal pressure of the balloon, so that an important reference basis is provided for doctors, the safety and effectiveness of surgical operation are ensured, and nerve injury or other negative effects caused by overhigh pressure of the balloon are avoided.
Owner:FIRST HOSPITAL OF QINHUANGDAO

Adjustable spraying device for local anesthesia

The utility model belongs to the technical field of spraying devices, and particularly relates to an adjustable spraying device for local anesthesia, which comprises a bottle body, a hydraulic device is mounted on the inner side of the bottle body, a first fixing part is sleeved at a top opening of the bottle body, and a second fixing part is inserted at the top of the first fixing part. The top of the second fixing part is connected with a spraying head in a sliding and inserted mode, the bottom end of the spraying head is located in the second fixing part and connected with a hydraulic device through a connecting pipe, and a circulation groove is formed in the inner side of the spraying head. When the anesthetic liquid is touched by mistake, the blocking plate is pushed to slide in the second sliding groove, one end of the blocking plate slides into the blocking groove in the opposite side, the circulation groove is completely blocked, and the risk that the anesthetic liquid flows out again to cause waste due to mistaken touch is avoided.
Owner:HEBEI PROVINCE CANGZHOU HOSPITAL OF INTEGRATED TRADITIONAL & WESTERN MEDICINE

A urinary control management system and method based on an intelligent urinary catheter

ActiveCN119924856BMedical data miningSensorsPatient dataUrinary control
The present invention relates to the technical field of healthcare informatics, and particularly relates to a urinary control management system and method based on an intelligent catheter, including: obtaining historical patient data during the catheter insertion process, thereby obtaining a scalar value sequence and a weight vector sequence of nodes in the hidden layer of the neural network architecture to screen out the target hidden layer, dividing each target hidden layer into several node groups, obtaining updated node groups, thereby obtaining a neural network with an updated architecture, training using a training data set, obtaining the trained neural network, thereby outputting the pain points during the catheter insertion process of the current patient, and performing local anesthesia on the pain points. The present invention can accurately identify the pain points during the catheter insertion process of the patient, and then perform local anesthesia on the pain points to improve the urinary control management effect.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN MEDICAL UNIV

Surgical platform for natural throat cavity

The invention relates to a throat natural cavity operation platform, and belongs to the technical field of medical instruments, the throat natural cavity operation platform comprises an operation table, a support frame, a lower support mechanism and a bendable throat cannula, the two ends of the operation table in the width direction are the front end and the rear end respectively, a patient sits in front of the operation table through a seat, and a doctor sits behind the operation table through the seat; the support frame is fixed on the table top close to the front part of the operating table; the lower support mechanism comprises an electric push rod and a lower jaw support; the electric push rod is fixed on the support frame and a telescopic end thereof reciprocates along the height direction of the support frame; the supporting frame is fixed to the telescopic end of the electric push rod. The throat cannula is located above the rear portion of the lower jaw support and fixed to the supporting frame. A traditional throat cavity operation platform structure is subverted, a sitting type operation is adopted to replace a horizontal type operation, the throat operation of local anesthesia can be implemented, the worry of a patient is reduced, the operation convenience of a doctor can be improved, the treatment effect is improved, and the medical cost is reduced.
Owner:韩嘉为 +1

Traditional Chinese medicine compound preparation based on antibiosis and anti-inflammation and preparation method thereof

The invention provides an antibacterial and anti-inflammatory traditional Chinese medicine compound preparation and a preparation method thereof. The compound preparation is prepared from the following raw materials in parts by weight: 10 to 30 parts of fructus forsythiae, 10 to 25 parts of flos chrysanthemi, 15 to 40 parts of rhizoma imperatae, 5 to 10 parts of herba menthae, 0.5 to 3 parts of borneol and 0.1 to 3 parts of camphor. The main innovation point of the formula is that triple mechanisms of clearing away heat and toxic materials, repairing mucous membranes and rapidly relieving pain are innovatively fused; instantaneous mucous membrane permeation is realized through volatile components (borneol, mint and camphor), and itching and pain are quickly relieved; forsythia suspense-chrysanthemum-couch grass root synergistically inhibit release of inflammatory factors and radically diminish swelling, and the specific functions are as follows: forsythia suspense has antibacterial and antiviral effects and inhibits streptococcus in throat; chrysanthemum has the effects of clearing liver fire, relieving heat toxin and eliminating mucosal hyperemia; the couch grass root can promote salivation, moisten dryness and repair damaged mucosa; mint is capable of quickly relieving itching and promoting transmembrane absorption of the medicine; borneol is used for instantly cooling and easing pain and opening a cell channel; and camphor and local anesthesia enhance the pain relieving time efficiency.
Owner:WUXI FORTUNE PHARMA

Compound with local anesthesia function as well as preparation method and application thereof

The invention discloses a compound with a local anesthesia function as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The preparation method of the compound comprises the following steps: mixing and heating lidocaine and 2-bromoethanol to obtain a compound 1; the preparation method comprises the following steps: mixing dicarboxylic acid, N-hydroxysuccinimide, 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride and a solvent to obtain a mixed solution; mixing and dissolving a compound 1, alkali and a solvent, and then adding into the mixed solution; and then carrying out spin-drying, separation and purification to obtain the compound with the local anesthesia function. The medicine can be used as a local anesthetic or analgesic for long-acting nerve block or selective nerve block. The medicine can block nerve conduction, has biocompatibility and biodegradability, is expected to overcome the problems of short time efficiency of single-needle injection and the like, and improves the efficacy of the medicine.
Owner:XUZHOU MEDICAL UNIVERSITY

Device for draining cerebrospinal fluid

PendingDE102024111829A1Wound drainsCatheterSubarachnoid spaceCerebral ventricular
The invention relates to a device (1) for draining cerebrospinal fluid, wherein the device (1) has a shaft (2) that can be implanted into a skull bone (14) of a human or animal, wherein the device (1) is suitable for draining cerebrospinal fluid from the subarachnoid space and / or a cerebral ventricle (15) into the diploë of the skull bone (14), and the shaft (2) has radially extending outlet openings (4), wherein a valve (17) is arranged inside the shaft (2) which connects a first chamber to a second chamber, wherein the second chamber has a fluid connection with the outlet openings (4), and a tube (5) opens into the shaft (2) at the distal end face of the shaft (2), or a tube (20) is arranged at the distal end face of the shaft (2) to which a tube (5) is connected.wherein the tube (5) in its proximal section or the pipe (20) is in fluid communication with the first chamber and the tube (5) has at least one distal inlet opening (8) for cerebrospinal fluid, wherein the inlet openings (8) can be placed in the subarachnoid space and / or in the region of a cerebral ventricle (15) and the tube (5) has a lumen (9) into which a wire (6) can be inserted, wherein the wire (6), when inserted, protrudes from the proximal end face of the device (1). The invention allows the treating physician to position and adjust the device (1) according to the requirements for draining the cerebrospinal fluid into the diploë of the skull bone (14). Placement is possible under local anesthesia.
Owner:CONTARA CSFD GMBH

Minimally invasive surgery treatment system for benign prostatic hyperplasia and use method thereof

The invention discloses a minimally invasive surgery treatment system for benign prostatic hyperplasia and a use method of the minimally invasive surgery treatment system. The system comprises an outer cannula used for entering the body of a patient through the urethra, a handle connected to the outer cannula, a cannula installed in the outer cannula, a stretching tube installed in the cannula, a guide wire installed in the stretching tube, a puncture needle head installed at the free end of the guide wire, a rotation driving mechanism used for driving the guide wire to rotate and a telescopic driving mechanism used for driving the cannula to move. A plurality of cutting knives which are uniformly arranged around the stretching tube are arranged between the free end of the stretching tube and the puncture needle head; a magnetic ring which is magnetically attracted with the puncture needle head is arranged at the free end of the sleeve; a guide wire locking mechanism used for locking the guide wire and a stretching pipe adjusting and locking mechanism used for adjusting the position of the stretching pipe and locking the stretching pipe are further arranged in the handle. The system is reasonable in structural design, the telescopic cutting knife is integrated into the puncture assembly, when the system is used for operation, trauma is small, recovery is fast, only local anesthesia is needed, the effect is fast, and the operation effect is good.
Owner:SHANGHAI BEICHEN XINRUI TECHNOLOGY PARTNERSHIP (LLP)

Guided injection for local anesthesia

There is provided a method comprising: detecting and / or segmenting a dental-related anatomical structure of a subject from a dental 3D imaging model, wherein the dental-related anatomical structure includes a target for injection of anesthesia by a dental syringe, accessing sequential frames of an oral cavity of a subject captured by an image sensor during a dental session of the subject, presenting within a GUI, at least one fused frame depicting a merger of the sequential frames and the segmentation of the dental-related anatomical structure of the subject registered to the sequential frames, wherein the dental-related anatomical structure is depicted on the sequential frames at a location indicating the target for injection, and dynamically updating the location of the dental-related anatomical structure depicted on the sequential frames according to dynamic adaptation of a pose of the image sensor.
Owner:MARS DENTAL AI LTD

Local anesthesia boosting instrument capable of controlling medicine pushing amount

ActiveCN223054878UAnaesthesiaAutomatic syringesAnesthesia needleDrive shaft
The utility model relates to the technical field of anesthesia boosting instruments, and discloses a local anesthesia boosting instrument capable of controlling the medicine pushing amount, which comprises a pushing cylinder, a thread area is arranged on the outer wall of the left end of the pushing cylinder, a thread ring is in threaded connection with the outside of the thread area, and movable grooves are formed in the upper side and the lower side of the left end of the pushing cylinder. A shell is fixedly connected to the right end of the pushing cylinder, a motor is fixedly connected to the exterior of the shell, an inner threaded sleeve is fixedly connected to a driving shaft of the motor, and a threaded rod is in threaded connection with the interior of the left end of the inner threaded sleeve. According to the anesthetic needle fixing device, the storage groove is rotated to be aligned with the movable ball, and at the moment, the fixed cylinder and the pushing cylinder can be mounted and dismounted, so that the anesthetic needle is convenient to replace, the threaded ring is matched with the limiting block, the injection metering of the anesthetic needle and the movement of the nut block and the connecting rod can be controlled, and the anesthetic needle in the middle is clamped by the clamping plates on the two sides; the anesthetic needle fixing device is simple and quick to operate.
Owner:ZIYANG SIMAIOU TECH CO LTD

Bionic artificial balloon type hip joint

The application relates to the technical field of femoral head necrosis treatment, in particular to a bionic artificial balloon type half hip joint, which comprises a sleeve, a femoral neck, a fixing screw and a femoral neck limiting nut, the sleeve is fixed on a femur through the fixing screw, the femoral neck is slidingly connected in the sleeve, a balloon is fixed on the outer periphery of the top section of the femoral neck, the inside of the femoral neck is hollow, and a side hole is arranged at the top end of the femoral neck and communicates with the balloon, and the femoral neck limiting nut is used for being fixed in the sleeve to position the femoral neck. The balloon type femoral head is compared with the metal and ceramic femoral heads, the balloon type femoral head is more matched with the shape of the acetabulum in terms of shape, the elastic modulus of the balloon type femoral head is equivalent to that of the bone cartilage of the acetabulum, the balloon type femoral head is beneficial to cartilage nutrition, and the wear of the bone cartilage of the acetabulum is small; the balloon is in a shriveled state when no filler is filled in the balloon, the balloon can be placed in the femur along the sleeve, the joint capsule and the medullary cavity do not need to be opened, the trauma is small, the risk of subsequent infection and dislocation is small, meanwhile, the prosthesis wear can be replaced through the sleeve, and the replacement is convenient and fast and can be completed under local anesthesia.
Owner:THE 958TH ARMY HOSPITAL OF THE CHINESE PEOPLES LIBERATION ARMY

Micro-power jaw lesion biopsy instrument

The invention relates to the technical field of medical instruments, in particular to a micro-power jaw lesion biopsy instrument which comprises a shell, a mounting part and a functional part. The mounting part is located in the shell, and a first driving assembly is arranged on the mounting part; the functional part is mounted on the mounting part and is a grinding assembly or a clamping assembly; one end of the functional part is detachably connected with the mounting part and is in driving connection with the first driving assembly; and the other end of the functional part is a functional end extending out of the shell. Compared with the prior art, the working assemblies can be switched, the functions of polishing a patient and grabbing diseased tissue are achieved, additional power punching equipment is not needed, biopsy of local anesthesia jaw bone diseases in the outpatient environment can be achieved, the working efficiency is improved, and the medical cost is reduced.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

An endoscope

The present application discloses an endoscope, comprising a mirror body; a first tube, the first tube is rotatably connected to the mirror body; a push rod, the push rod is spline-connected to the first tube; a pull rod, the pull rod is arranged inside the push rod, and the end of the pull rod passes through the push rod; a nozzle, the nozzle is rotatably connected to the end of the push rod; a first trigger, the first trigger is connected to the push rod; and a second trigger, the second trigger is connected to the pull rod. The present application integrates the first, second, third, and fourth triggers, which respectively control different actions of the nozzle. When anesthesia is required for a certain area in the body during surgery, local anesthesia can be achieved through the nozzle, and the operation is simple and convenient; pressing the first trigger can move the push rod forward to expose the nozzle and the position can be locked; when the second trigger is pressed, the first tube reciprocates to make the nozzle swing back and forth, and anesthetics are sprayed through the nozzle at the same time, and due to the cooperation of the arc-shaped rack, cam, and tilting rod, the arc-shaped rack can drive the cam to rotate multiple times in one back and forth stroke, so that the anesthetic spraying is more uniform.
Owner:HANGZHOU SUODE MEDICAL EQUIP CO LTD

Balloon catheter assembly for combined local anesthesia and balloon dilatation

The present invention relates to a balloon catheter assembly for jointly performing local anesthesia and balloon dilatation, comprising a balloon catheter and a guide wire, the balloon catheter comprising: a handle provided with a cavity, and a discharge port, a main channel and a secondary channel communicating with the cavity; the balloon is arranged at one end, far away from the handle, of the balloon catheter; one end of the inner core catheter is communicated with the main channel in the cavity of the handle, the other end of the inner core catheter extends from the cavity of the handle, penetrates through the discharge port and reaches an inner core catheter outlet of the inner core catheter, and the inner core catheter outlet is communicated with the interior of the balloon; and an outer core catheter disposed outside of the inner core catheter and having one end in communication with the secondary passage in the cavity of the handle and the other end extending from the cavity of the handle through the discharge port to an outer core catheter outlet of the outer core catheter, the outer core catheter outlet communicating with the outside of the balloon catheter, and wherein the outer core catheter is disposed outside of the balloon catheter. The diameter of the guide wire is smaller than the inner diameter of the inner core catheter of the balloon catheter, so that the guide wire can be introduced into the inner core catheter.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Micro-needle anesthesia analgesia system and method for painless local anesthesia injection

The invention provides a microneedle anesthesia analgesia system and method for painless local anesthesia injection, and the system comprises a bionic gradient microneedle array, a mechanical drive module, an electromagnetic lead-in module, a multi-mode biosensor and a PID controller. The bionic gradient microneedle array is connected with the mechanical driving module and the electromagnetic leading-in module; the electromagnetic lead-in module is used for promoting the diffusion of the anesthetic in the in-vivo tissue; the multi-mode biosensor is used for monitoring the concentration of anesthetic in vivo, the pH value of tissues and drug metabolites in real time and sending the acquired information to the PID controller; and the PID controller is used for dynamically adjusting the microneedle penetration length, the drug release rate and the electromagnetic introduction intensity parameter according to the information sent by the multi-mode biosensor. By means of the technical scheme, the local anesthesia analgesic effect without injection pain is truly achieved.
Owner:BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY

A deformable local anesthesia puncture medicine injection system

The application discloses a deformable local anesthesia puncture medicine injection system and belongs to the technical field of medical devices; the system comprises an injection pump body, a first branch and a second branch with variable included angles, the first branch and the second branch being connected with the injection pump body through a first pipeline, the lower surfaces of the first branch and the second branch being provided with local anesthesia needles, a third branch and a fourth branch with variable included angles, the third branch and the fourth branch being connected with the injection pump body through a second pipeline, the third branch and the fourth branch being provided with adhering films, an internal transmission mechanism arranged in the injection pump body, and an external control module arranged on the outer surface of the injection pump body and connected with the internal transmission mechanism in control. In the application, the first branch and the second branch can be adjusted to the shape for realizing one-time local anesthesia of a diseased part and covering the diseased part, and the anesthesia of the diseased part is avoided for multiple times.
Owner:GENERAL HOSPITAL OF THE NORTHERN WAR ZONE OF THE CHINESE PEOPLES LIBERATION ARMY

Gamma-PGA-based local anesthesia patch

The utility model relates to the technical field of medical instruments, in particular to a gamma-PGA-based local anesthesia patch which comprises an adjusting assembly, a protective layer, a waterproof layer, a gamma-PGA layer, an anesthetic layer and a release film which are sequentially arranged from top to bottom. One side edge of the protective layer is a stress edge; the adjusting assembly comprises a locking mechanism and a plurality of adjusting strips, one ends of the adjusting strips are connected to the stress edge, and the free ends of the adjusting strips penetrate through the locking mechanism to fix the adjusting strips through the locking mechanism. According to the utility model, the gamma-PGA layer is used, so that the patch has high moisture retention and high viscosity and can be attached to the skin, the allergic reaction or other uncomfortable reactions of the skin can be reduced due to the moisture retention, and drugs in the anesthetic layer can be retained in the gamma-PGA layer, so that a slow-release effect is achieved; the gamma-PGA layer can be extruded by pulling force in cooperation with the adjusting assembly, so that the release speed is increased, and the requirements of different crowds for the amount of anesthetic are met.
Owner:李荣钢

Treatment system for vein malformation treatment and use method thereof

The invention belongs to the technical field of medical treatment, and particularly relates to a treatment system for vein malformation treatment and a use method of the treatment system, and the treatment system comprises a console, a magnetic resonance imaging module, a digital silhouette angiography module, an ultrasonic imaging module, a multi-angle percutaneous puncture module and the like. The venous malformation treatment system integrates the magnetic resonance imaging module, the digital silhouette angiography module, the ultrasonic imaging module and the multi-angle percutaneous puncture module, achieves accurate positioning and efficient treatment, improves puncture accuracy, reduces complications, accurately controls hardener conveying, optimizes the treatment effect and reduces the drug use risk through real-time image guidance, and has good application prospects. Local anesthesia swelling liquid reduces thrombus shedding, protects normal veins, avoids high-value consumable implantation and reduces cost, the system is particularly suitable for children, avoids damage to backflow veins and guarantees safety, and generally, the system remarkably improves the accuracy, safety and economical efficiency of venous malformation treatment and brings better treatment experience to child patients.
Owner:河南省儿童医院郑州儿童医院

Needle head protective cover for oral local anesthesia injection needle

The utility model provides an oral cavity local anesthesia injection needle head protective cover, which belongs to the technical field of medical appliances and comprises a needle tube, a groove is arranged on the outer side of the needle tube, a plurality of first springs are arranged in the groove, a telescopic plate is arranged above the plurality of first springs, and a first telescopic rod is arranged in the middle of each first spring. A penetrating hole is formed in the side face of the needle tube above the telescopic plate, a fixing piece is arranged at the penetrating hole, a sliding block is arranged on the side, close to the telescopic plate, of the fixing piece, a cabin is arranged in the connecting piece, a second spring is arranged on the side face of the sliding block in the cabin in the connecting piece, and a hole is formed in the position, at the center of the second spring, of the connecting piece. According to the anesthetic injection needle, a layer of limiting area can be rapidly formed on the periphery of the injection needle after anesthetic injection is completed, medical staff can operate the anesthetic injection needle with one hand through the button, and the problems of medical exposure and the like caused by pricking injury can be effectively solved.
Owner:TIANJIN DENTAL HOSPITAL

Mu-type conotoxin peptide, polynucleotide coded by mu-type conotoxin peptide and application of mu-type conotoxin peptide

The invention discloses a mu-type conotoxin peptide, polynucleotide encoded by the mu-type conotoxin peptide and application of the mu-type conotoxin peptide. The amino acid sequence of the mu-type conotoxin peptide is shown as SEQ ID NO. 1. The invention provides a mu-type conotoxin peptide with higher biological activity than wild-type mu-type conotoxin, which can specifically block a Nav1.4 channel and reduce muscle contraction so as to be helpful for preventing and reducing wrinkles, and also can provide local anesthesia and reduce muscle activity, thereby playing an important role in the fields of beauty and medical treatment.
Owner:PEPTIORIGIN BIOTECHNOLOGY CO LTD

Adjustable needle head assembly for auxiliary analgesia of minimally invasive local anesthesia

The invention discloses an adjustable needle head assembly for auxiliary analgesia of minimally invasive local anesthesia, and relates to the field of medical equipment, the adjustable needle head assembly comprises three injection cylinders and a sleeving cylinder, the three injection cylinders are all sleeved with connecting hoses, and the connecting hoses are connected with needle heads. It needs to be explained that in the embodiment of the invention, the rotating frame is rotated to drive the three arc-shaped pushing frames to rotate, then the extrusion pushing frame is made to move to drive the needle head to conduct anesthesia, scales are arranged on the extrusion pushing frame, the entering depth of the needle head can be effectively adjusted, a patient cannot directly see the needle head, and the fear of the patient is eliminated; the consistent puncturing depth can be ensured, so that the same medicine effect is ensured, and precise anesthesia is realized; besides, the disinfection rotary drum disinfects the fingers through a plurality of disinfection cotton pieces and is clamped to the palm of the patient through two supporting sliding frames, the situation that the entering depth of the needle cannot meet the requirement due to the fact that the fingers of the patient are bent up and down in the anesthesia process is avoided, and therefore the needle assembly is convenient to use and can guarantee the anesthesia effect.
Owner:FIRST HOSPITAL OF SHANXI MEDICAL UNIV

A traditional Chinese medicine composition library based on general and local anesthesia mechanisms, and various dosage forms and preparation methods thereof

PendingCN122499221AEphedra sinicaMedicinal herbs
This invention discloses a library of traditional Chinese medicine (TCM) compositions based on general and local anesthesia mechanisms, along with various dosage forms and preparation methods. The invention constructs a systematic library of TCM anesthetic compositions: the general anesthetic composition consists of extracts from herbs such as Datura stramonium, Datura stramonium, processed Aconitum carmichaelii, processed Aconitum kusnezoffii, Saussurea involucrata, Jasminum sambac root, Rhododendron molle, and Sanqie Sanqie; the local anesthetic composition consists of extracts from herbs such as Asarum heterotropoides, Murraya paniculata, Ephedra sinica, Toad venom, and Corydalis yanhusuo. This invention further develops the above compositions into various modern dosage forms, including injections, tablets, capsules, and sprays. In particular, this invention innovatively introduces a clove-cinnamon natural preservative and flavoring system to replace chemical preservatives. In terms of preparation technology, advanced technologies such as supercritical CO2 extraction, microwave-assisted extraction, nano-embedding, and nanoemulsions are integrated, and a self-extraction scheme is adopted to achieve controllable quality and cost. Simultaneously, a quality detection method based on HPLC fingerprinting is established. This invention achieves full-scenario coverage of anesthesia and analgesia, from general to local, from emergency to routine care, with outstanding advantages of safety, effectiveness, and controllable quality.
Owner:杨伟学

Ar marker for injection

Disclosed is an AR self-injection training system and method of use incorporating a marker specifically designed for device-naive self-injection patients. The marker is designed so that it can be removably adhered to an injection site. Once in position it anchors AR content to the injection site for training. The marker is designed to associate AR content to the injection site for training and allows patient to leave the marker in place and inject to the same site. Providing a system that is able to identify a site of injection and to provide salient instructions streamlines the process of training and makes the transition to using a real-device relatively seamless. The provided embodiments can also incorporate error correction functionality and even local anesthesia or analgesic. Following training, the opening in the marker allows patients to leave the marker in place and inject to the same site.
Owner:NOBLE INT INC

Local anesthesia intervention preoperative diet planning system

The invention relates to a local anesthesia intervention preoperative diet planning system, and belongs to the technical field of preoperative diet management. The system comprises: a fluorescence measurement unit configured to determine a gastric emptying trend line of a patient using fluorescence indication during a preoperative planning phase; the diet planning unit is configured to generate feeding time and feeding type planning of the patient according to the gastric emptying trend line of the patient and preset operation time; the blood glucose detection unit is configured to monitor the blood glucose of the patient in real time. Preferably, the diet planning unit is further configured to individually correct the gastric emptying rate of the patient according to the real-time monitoring value of the blood glucose of the patient, and adjust the feeding time and feeding type planning of the patient according to the corrected gastric emptying rate.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI