60 results about "Local anesthesia" patented technology

There is provided a method comprising: detecting and / or segmenting a dental-related anatomical structure of a subject from a dental 3D imaging model, wherein the dental-related anatomical structure includes a target for injection of anesthesia by a dental syringe, accessing sequential frames of an oral cavity of a subject captured by an image sensor during a dental session of the subject, presenting within a GUI, at least one fused frame depicting a merger of the sequential frames and the segmentation of the dental-related anatomical structure of the subject registered to the sequential frames, wherein the dental-related anatomical structure is depicted on the sequential frames at a location indicating the target for injection, and dynamically updating the location of the dental-related anatomical structure depicted on the sequential frames according to dynamic adaptation of a pose of the image sensor.

According to the puncture assembly for the trigeminal nerve meniscus balloon compression operation under local anesthesia, firstly, an anesthetic needle is designed to be of a detachable structure and can be arranged in a puncture needle in a sliding and sleeving mode, and precise local anesthesia is conducted firstly in the puncture process; then the same puncture channel is used for carrying out subsequent balloon catheter insertion operation; and secondly, the balloon is fixedly arranged at the front end of the balloon catheter and is connected with the balloon dilatation pressure pump, so that moderate compression on the trigeminal nerve meniscus can be realized by accurately controlling the filling degree of the balloon in the operation process. Meanwhile, the pressure pump has a real-time monitoring function on the internal pressure of the balloon, so that an important reference basis is provided for doctors, the safety and effectiveness of surgical operation are ensured, and nerve injury or other negative effects caused by overhigh pressure of the balloon are avoided.

The utility model belongs to the technical field of spraying devices, and particularly relates to an adjustable spraying device for local anesthesia, which comprises a bottle body, a hydraulic device is mounted on the inner side of the bottle body, a first fixing part is sleeved at a top opening of the bottle body, and a second fixing part is inserted at the top of the first fixing part. The top of the second fixing part is connected with a spraying head in a sliding and inserted mode, the bottom end of the spraying head is located in the second fixing part and connected with a hydraulic device through a connecting pipe, and a circulation groove is formed in the inner side of the spraying head. When the anesthetic liquid is touched by mistake, the blocking plate is pushed to slide in the second sliding groove, one end of the blocking plate slides into the blocking groove in the opposite side, the circulation groove is completely blocked, and the risk that the anesthetic liquid flows out again to cause waste due to mistaken touch is avoided.

The invention relates to a throat natural cavity operation platform, and belongs to the technical field of medical instruments, the throat natural cavity operation platform comprises an operation table, a support frame, a lower support mechanism and a bendable throat cannula, the two ends of the operation table in the width direction are the front end and the rear end respectively, a patient sits in front of the operation table through a seat, and a doctor sits behind the operation table through the seat; the support frame is fixed on the table top close to the front part of the operating table; the lower support mechanism comprises an electric push rod and a lower jaw support; the electric push rod is fixed on the support frame and a telescopic end thereof reciprocates along the height direction of the support frame; the supporting frame is fixed to the telescopic end of the electric push rod. The throat cannula is located above the rear portion of the lower jaw support and fixed to the supporting frame. A traditional throat cavity operation platform structure is subverted, a sitting type operation is adopted to replace a horizontal type operation, the throat operation of local anesthesia can be implemented, the worry of a patient is reduced, the operation convenience of a doctor can be improved, the treatment effect is improved, and the medical cost is reduced.

The invention provides an antibacterial and anti-inflammatory traditional Chinese medicine compound preparation and a preparation method thereof. The compound preparation is prepared from the following raw materials in parts by weight: 10 to 30 parts of fructus forsythiae, 10 to 25 parts of flos chrysanthemi, 15 to 40 parts of rhizoma imperatae, 5 to 10 parts of herba menthae, 0.5 to 3 parts of borneol and 0.1 to 3 parts of camphor. The main innovation point of the formula is that triple mechanisms of clearing away heat and toxic materials, repairing mucous membranes and rapidly relieving pain are innovatively fused; instantaneous mucous membrane permeation is realized through volatile components (borneol, mint and camphor), and itching and pain are quickly relieved; forsythia suspense-chrysanthemum-couch grass root synergistically inhibit release of inflammatory factors and radically diminish swelling, and the specific functions are as follows: forsythia suspense has antibacterial and antiviral effects and inhibits streptococcus in throat; chrysanthemum has the effects of clearing liver fire, relieving heat toxin and eliminating mucosal hyperemia; the couch grass root can promote salivation, moisten dryness and repair damaged mucosa; mint is capable of quickly relieving itching and promoting transmembrane absorption of the medicine; borneol is used for instantly cooling and easing pain and opening a cell channel; and camphor and local anesthesia enhance the pain relieving time efficiency.

The invention discloses a compound with a local anesthesia function as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The preparation method of the compound comprises the following steps: mixing and heating lidocaine and 2-bromoethanol to obtain a compound 1; the preparation method comprises the following steps: mixing dicarboxylic acid, N-hydroxysuccinimide, 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride and a solvent to obtain a mixed solution; mixing and dissolving a compound 1, alkali and a solvent, and then adding into the mixed solution; and then carrying out spin-drying, separation and purification to obtain the compound with the local anesthesia function. The medicine can be used as a local anesthetic or analgesic for long-acting nerve block or selective nerve block. The medicine can block nerve conduction, has biocompatibility and biodegradability, is expected to overcome the problems of short time efficiency of single-needle injection and the like, and improves the efficacy of the medicine.

The invention relates to a device (1) for draining cerebrospinal fluid, wherein the device (1) has a shaft (2) that can be implanted into a skull bone (14) of a human or animal, wherein the device (1) is suitable for draining cerebrospinal fluid from the subarachnoid space and / or a cerebral ventricle (15) into the diploë of the skull bone (14), and the shaft (2) has radially extending outlet openings (4), wherein a valve (17) is arranged inside the shaft (2) which connects a first chamber to a second chamber, wherein the second chamber has a fluid connection with the outlet openings (4), and a tube (5) opens into the shaft (2) at the distal end face of the shaft (2), or a tube (20) is arranged at the distal end face of the shaft (2) to which a tube (5) is connected.wherein the tube (5) in its proximal section or the pipe (20) is in fluid communication with the first chamber and the tube (5) has at least one distal inlet opening (8) for cerebrospinal fluid, wherein the inlet openings (8) can be placed in the subarachnoid space and / or in the region of a cerebral ventricle (15) and the tube (5) has a lumen (9) into which a wire (6) can be inserted, wherein the wire (6), when inserted, protrudes from the proximal end face of the device (1). The invention allows the treating physician to position and adjust the device (1) according to the requirements for draining the cerebrospinal fluid into the diploë of the skull bone (14). Placement is possible under local anesthesia.

The invention discloses a minimally invasive surgery treatment system for benign prostatic hyperplasia and a use method of the minimally invasive surgery treatment system. The system comprises an outer cannula used for entering the body of a patient through the urethra, a handle connected to the outer cannula, a cannula installed in the outer cannula, a stretching tube installed in the cannula, a guide wire installed in the stretching tube, a puncture needle head installed at the free end of the guide wire, a rotation driving mechanism used for driving the guide wire to rotate and a telescopic driving mechanism used for driving the cannula to move. A plurality of cutting knives which are uniformly arranged around the stretching tube are arranged between the free end of the stretching tube and the puncture needle head; a magnetic ring which is magnetically attracted with the puncture needle head is arranged at the free end of the sleeve; a guide wire locking mechanism used for locking the guide wire and a stretching pipe adjusting and locking mechanism used for adjusting the position of the stretching pipe and locking the stretching pipe are further arranged in the handle. The system is reasonable in structural design, the telescopic cutting knife is integrated into the puncture assembly, when the system is used for operation, trauma is small, recovery is fast, only local anesthesia is needed, the effect is fast, and the operation effect is good.

There is provided a method comprising: detecting and / or segmenting a dental-related anatomical structure of a subject from a dental 3D imaging model, wherein the dental-related anatomical structure includes a target for injection of anesthesia by a dental syringe, accessing sequential frames of an oral cavity of a subject captured by an image sensor during a dental session of the subject, presenting within a GUI, at least one fused frame depicting a merger of the sequential frames and the segmentation of the dental-related anatomical structure of the subject registered to the sequential frames, wherein the dental-related anatomical structure is depicted on the sequential frames at a location indicating the target for injection, and dynamically updating the location of the dental-related anatomical structure depicted on the sequential frames according to dynamic adaptation of a pose of the image sensor.

The application relates to the technical field of femoral head necrosis treatment, in particular to a bionic artificial balloon type half hip joint, which comprises a sleeve, a femoral neck, a fixing screw and a femoral neck limiting nut, the sleeve is fixed on a femur through the fixing screw, the femoral neck is slidingly connected in the sleeve, a balloon is fixed on the outer periphery of the top section of the femoral neck, the inside of the femoral neck is hollow, and a side hole is arranged at the top end of the femoral neck and communicates with the balloon, and the femoral neck limiting nut is used for being fixed in the sleeve to position the femoral neck. The balloon type femoral head is compared with the metal and ceramic femoral heads, the balloon type femoral head is more matched with the shape of the acetabulum in terms of shape, the elastic modulus of the balloon type femoral head is equivalent to that of the bone cartilage of the acetabulum, the balloon type femoral head is beneficial to cartilage nutrition, and the wear of the bone cartilage of the acetabulum is small; the balloon is in a shriveled state when no filler is filled in the balloon, the balloon can be placed in the femur along the sleeve, the joint capsule and the medullary cavity do not need to be opened, the trauma is small, the risk of subsequent infection and dislocation is small, meanwhile, the prosthesis wear can be replaced through the sleeve, and the replacement is convenient and fast and can be completed under local anesthesia.

The invention relates to the technical field of medical instruments, in particular to a micro-power jaw lesion biopsy instrument which comprises a shell, a mounting part and a functional part. The mounting part is located in the shell, and a first driving assembly is arranged on the mounting part; the functional part is mounted on the mounting part and is a grinding assembly or a clamping assembly; one end of the functional part is detachably connected with the mounting part and is in driving connection with the first driving assembly; and the other end of the functional part is a functional end extending out of the shell. Compared with the prior art, the working assemblies can be switched, the functions of polishing a patient and grabbing diseased tissue are achieved, additional power punching equipment is not needed, biopsy of local anesthesia jaw bone diseases in the outpatient environment can be achieved, the working efficiency is improved, and the medical cost is reduced.

The present invention relates to a balloon catheter assembly for jointly performing local anesthesia and balloon dilatation, comprising a balloon catheter and a guide wire, the balloon catheter comprising: a handle provided with a cavity, and a discharge port, a main channel and a secondary channel communicating with the cavity; the balloon is arranged at one end, far away from the handle, of the balloon catheter; one end of the inner core catheter is communicated with the main channel in the cavity of the handle, the other end of the inner core catheter extends from the cavity of the handle, penetrates through the discharge port and reaches an inner core catheter outlet of the inner core catheter, and the inner core catheter outlet is communicated with the interior of the balloon; and an outer core catheter disposed outside of the inner core catheter and having one end in communication with the secondary passage in the cavity of the handle and the other end extending from the cavity of the handle through the discharge port to an outer core catheter outlet of the outer core catheter, the outer core catheter outlet communicating with the outside of the balloon catheter, and wherein the outer core catheter is disposed outside of the balloon catheter. The diameter of the guide wire is smaller than the inner diameter of the inner core catheter of the balloon catheter, so that the guide wire can be introduced into the inner core catheter.

The invention provides a microneedle anesthesia analgesia system and method for painless local anesthesia injection, and the system comprises a bionic gradient microneedle array, a mechanical drive module, an electromagnetic lead-in module, a multi-mode biosensor and a PID controller. The bionic gradient microneedle array is connected with the mechanical driving module and the electromagnetic leading-in module; the electromagnetic lead-in module is used for promoting the diffusion of the anesthetic in the in-vivo tissue; the multi-mode biosensor is used for monitoring the concentration of anesthetic in vivo, the pH value of tissues and drug metabolites in real time and sending the acquired information to the PID controller; and the PID controller is used for dynamically adjusting the microneedle penetration length, the drug release rate and the electromagnetic introduction intensity parameter according to the information sent by the multi-mode biosensor. By means of the technical scheme, the local anesthesia analgesic effect without injection pain is truly achieved.

The application discloses a deformable local anesthesia puncture medicine injection system and belongs to the technical field of medical devices; the system comprises an injection pump body, a first branch and a second branch with variable included angles, the first branch and the second branch being connected with the injection pump body through a first pipeline, the lower surfaces of the first branch and the second branch being provided with local anesthesia needles, a third branch and a fourth branch with variable included angles, the third branch and the fourth branch being connected with the injection pump body through a second pipeline, the third branch and the fourth branch being provided with adhering films, an internal transmission mechanism arranged in the injection pump body, and an external control module arranged on the outer surface of the injection pump body and connected with the internal transmission mechanism in control. In the application, the first branch and the second branch can be adjusted to the shape for realizing one-time local anesthesia of a diseased part and covering the diseased part, and the anesthesia of the diseased part is avoided for multiple times.

The invention belongs to the technical field of medical treatment, and particularly relates to a treatment system for vein malformation treatment and a use method of the treatment system, and the treatment system comprises a console, a magnetic resonance imaging module, a digital silhouette angiography module, an ultrasonic imaging module, a multi-angle percutaneous puncture module and the like. The venous malformation treatment system integrates the magnetic resonance imaging module, the digital silhouette angiography module, the ultrasonic imaging module and the multi-angle percutaneous puncture module, achieves accurate positioning and efficient treatment, improves puncture accuracy, reduces complications, accurately controls hardener conveying, optimizes the treatment effect and reduces the drug use risk through real-time image guidance, and has good application prospects. Local anesthesia swelling liquid reduces thrombus shedding, protects normal veins, avoids high-value consumable implantation and reduces cost, the system is particularly suitable for children, avoids damage to backflow veins and guarantees safety, and generally, the system remarkably improves the accuracy, safety and economical efficiency of venous malformation treatment and brings better treatment experience to child patients.

The utility model provides an oral cavity local anesthesia injection needle head protective cover, which belongs to the technical field of medical appliances and comprises a needle tube, a groove is arranged on the outer side of the needle tube, a plurality of first springs are arranged in the groove, a telescopic plate is arranged above the plurality of first springs, and a first telescopic rod is arranged in the middle of each first spring. A penetrating hole is formed in the side face of the needle tube above the telescopic plate, a fixing piece is arranged at the penetrating hole, a sliding block is arranged on the side, close to the telescopic plate, of the fixing piece, a cabin is arranged in the connecting piece, a second spring is arranged on the side face of the sliding block in the cabin in the connecting piece, and a hole is formed in the position, at the center of the second spring, of the connecting piece. According to the anesthetic injection needle, a layer of limiting area can be rapidly formed on the periphery of the injection needle after anesthetic injection is completed, medical staff can operate the anesthetic injection needle with one hand through the button, and the problems of medical exposure and the like caused by pricking injury can be effectively solved.

The invention discloses a mu-type conotoxin peptide, polynucleotide encoded by the mu-type conotoxin peptide and application of the mu-type conotoxin peptide. The amino acid sequence of the mu-type conotoxin peptide is shown as SEQ ID NO. 1. The invention provides a mu-type conotoxin peptide with higher biological activity than wild-type mu-type conotoxin, which can specifically block a Nav1.4 channel and reduce muscle contraction so as to be helpful for preventing and reducing wrinkles, and also can provide local anesthesia and reduce muscle activity, thereby playing an important role in the fields of beauty and medical treatment.

This invention discloses a library of traditional Chinese medicine (TCM) compositions based on general and local anesthesia mechanisms, along with various dosage forms and preparation methods. The invention constructs a systematic library of TCM anesthetic compositions: the general anesthetic composition consists of extracts from herbs such as Datura stramonium, Datura stramonium, processed Aconitum carmichaelii, processed Aconitum kusnezoffii, Saussurea involucrata, Jasminum sambac root, Rhododendron molle, and Sanqie Sanqie; the local anesthetic composition consists of extracts from herbs such as Asarum heterotropoides, Murraya paniculata, Ephedra sinica, Toad venom, and Corydalis yanhusuo. This invention further develops the above compositions into various modern dosage forms, including injections, tablets, capsules, and sprays. In particular, this invention innovatively introduces a clove-cinnamon natural preservative and flavoring system to replace chemical preservatives. In terms of preparation technology, advanced technologies such as supercritical CO2 extraction, microwave-assisted extraction, nano-embedding, and nanoemulsions are integrated, and a self-extraction scheme is adopted to achieve controllable quality and cost. Simultaneously, a quality detection method based on HPLC fingerprinting is established. This invention achieves full-scenario coverage of anesthesia and analgesia, from general to local, from emergency to routine care, with outstanding advantages of safety, effectiveness, and controllable quality.

Disclosed is an AR self-injection training system and method of use incorporating a marker specifically designed for device-naive self-injection patients. The marker is designed so that it can be removably adhered to an injection site. Once in position it anchors AR content to the injection site for training. The marker is designed to associate AR content to the injection site for training and allows patient to leave the marker in place and inject to the same site. Providing a system that is able to identify a site of injection and to provide salient instructions streamlines the process of training and makes the transition to using a real-device relatively seamless. The provided embodiments can also incorporate error correction functionality and even local anesthesia or analgesic. Following training, the opening in the marker allows patients to leave the marker in place and inject to the same site.

The embodiment of the invention provides an operating bed with a turning-over assisting function, and relates to the technical field of medical instruments. The operating bed with the turning-over assisting function comprises a base plate, a mounting body, two first bed plates and two second bed plates, the mounting body is fixedly connected with the base plate, the two first bed plates are rotatably connected with the base plate, two driving assemblies are arranged on the base plate, and the output ends of the two driving assemblies are connected with the two first bed plates; the two second bed plates are rotationally connected with the two first bed plates respectively; a transmission assembly is arranged between the first bed board and the second bed board. The problems of large physical output, low operation efficiency and the like caused by the fact that a general anesthesia patient or a local anesthesia patient needs to turn over manually by medical staff in the operation process are effectively solved, it is ensured that the turning-over process is stable, controllable, safe and reliable, and the workload of the medical staff is greatly relieved.

The application discloses a method for establishing an angle-closure glaucoma animal model. The method comprises the following steps: performing mydriasis on an eye of an animal model after general anesthesia, performing local anesthesia on an eye surface of the model eye after 10 minutes; after the pupil of the model eye is reduced, eye gel is added to the eye surface; a semiconductor laser is used to uniformly hit a plurality of laser points at an iris margin; and eye drops are added to the eye surface after laser treatment. The method uses a 532nm laser to hit the iris margin, causes local edema of the iris margin, narrows a passage through which aqueous humor flows from the posterior chamber into the anterior chamber, and increases the pressure of the posterior chamber. The method can keep the high intraocular pressure of the established angle-closure glaucoma animal model between 20-30mmHg, the success rate is 70%, the high intraocular pressure can be maintained for more than one week, no wound is caused on the eye of the animal model, there is no inflammatory reaction on the eye surface, the cornea has no edema and new blood vessels, and the operation of the model can be completed within 10 minutes.

The application discloses a local anesthetic device for oral cavity and relates to the technical field of medical auxiliary appliances. The appearance shape of the needle causes fear in people, and the exposed needle can make people focus on the pain caused by the needle when the injection is performed, so that the pain is increased. The application provides a local anesthetic device for oral cavity, which comprises a liquid pushing structure, a medicine liquid containing tube and an operating tube connected in an axial direction, and an injection structure arranged at the other end of the medicine liquid containing tube and comprising a retractable needle. The visual fear of the patient can be relieved by the design of the needle shielding structure, the anxiety is reduced, the treatment compliance is improved, and the operation risk is reduced. Meanwhile, the liquid pushing assembly is designed, so that the medical staff can perform one-handed operation.

The invention discloses a degradable slow-release long-acting microneedle patch, a preparation method and application, and belongs to the field of biomedical materials.The preparation method comprises the steps that a medicine solution and reversible temperature-sensitive chitin are mixed at the gel transition temperature to obtain a medicine-containing base material aqueous solution, and array microneedles are obtained after mold pouring, heating and drying; then pouring a microneedle base to obtain the degradable slow-release long-acting microneedle patch, wherein the drug solution is a local anesthesia analgesic and / or an anti-inflammatory and antibacterial drug; the prepared array microneedle can be punctured into the superficial layer of the skin for administration, is insoluble in water under physiological conditions but swells slowly when encountering water, transdermal sustained-release medicine is realized, the action time of the medicine is prolonged, the problem that the action time of the existing local anesthesia analgesic is short is solved, and the compliance of a patient is improved. The prepared microneedle patch has good biodegradability, biocompatibility and biological activity and is high in safety, and the prepared microneedle patch is easy to store and convenient to use and has commercial application potential.

The application discloses a minimally invasive fixing device suitable for correction of a concealed penis, which is a non-surgical correction device, comprising a hollow puncture needle, a shrapnel assembly implantable into a human body and a medical suture; a shrapnel push rod capable of pushing the shrapnel assembly out of the puncture needle is arranged in the pipe body of the puncture needle; the shrapnel assembly is arranged in the puncture tip of the puncture needle in a curved shape and is automatically opened after being pushed out by the shrapnel push rod; one end of the medical suture is fixedly connected with the shrapnel assembly, and the other end is led out through the pipe body end of the puncture needle along the length direction of the puncture needle. The shrapnel assembly is bent and accommodated in the puncture tip of the puncture needle, the shrapnel push rod is used for pushing the shrapnel assembly out and automatically opening, and the rapid implantation and anchoring operation under a single puncture path are realized. The conventional general anesthesia correction operation can be replaced, no incision under local anesthesia, rapid correction are realized, and a non-surgical method for the concealed penis is realized, which is local anesthesia, super micro-invasive, rapid correction and safer.

A silicone implant is fixed onto the thyroid cartilage and the implant has a guide channel extending therethrough. The placement allows fixation to the cartilage by blade portions on opposite sides of the implant, with the guide channel being positioned in front of the muscles to be treated. The implant enables safe, accurate, and repeatable injections into internal laryngeal muscles under local anesthesia, and simplifies surgical access, increases accuracy, and reduces risks associated with traditional techniques.

The invention relates to a local anesthesia dosage control system based on CFD (Computational Fluid Dynamics) and PC-MRI (Personal Computer-Magnetic Resonance Imaging) coupling and a working method thereof, and the system comprises an information collection unit which is used for collecting physical examination and medical evaluation information of a patient; the geometric unit is used for acquiring a T2 weighted MRI image sequence; the calculation model unit is used for determining the range of a lumbar, thoracic and vertebral segment calculation domain; a measurement unit for phase encoding using PC-MRI; the cerebrospinal fluid dynamic unit is used for acquiring an initial flow field of cerebrospinal fluid flow of the spinal canal of the patient; the dosage selection unit is used for selecting the injection dosage of the local anesthetic; the intrathecal administration calculation unit is used for establishing coupling analysis to obtain a local anesthetic concentration value of a blocking plane; and the dose evaluation unit is used for quantitatively evaluating the concentration value of the local anesthetic. The system is beneficial for improving the accuracy and safety of local anesthesia medication.

The invention relates to the technical field of medical instruments, and discloses a rib intraosseous fixing support, a mounting method and a dismounting method.The rib intraosseous fixing support comprises a first connecting plate and a second connecting plate, the first connecting plate and the second connecting plate are connected through a hollow bolt, and extension sections are arranged on the upper surface of the hollow bolt towards the two sides along the surface of the second connecting plate; the extension section is larger than the through hole of the second connecting plate penetrating through the hollow bolt; a central column is connected in the hollow bolt, and the upper end of the central column is connected with a cap-shaped nut. During installation, a window is formed in the surface of a rib, the linear fixing support is rotated to be laterally placed in the rib, and the linear fixing support is adjusted to be an X-shaped fixing support through a tool after being rotated by 90 degrees and fixed through a cap-shaped nut. During dismounting, only the cap-shaped nut, the central column and the hollow bolt are dismounted. Compared with the prior art, built-in and fixation of ribs of the fixing support are achieved, in the using process, the intraosseous support can be fixed only by conducting local anesthesia on a patient to achieve small-range opening, the wound is small, the later influence is small, and dismounting is convenient.

The invention provides a ripdicaine emulsifiable paste and a preparation process thereof. According to the invention, a new cream formula is selected, the transdermal absorption is faster than that of a preparation without a penetration enhancer, the anesthesia time is shortened, and the waiting time of a patient is reduced. Compared with the prior art, the new penetration enhancer has the advantages that the irritation of damaged skin is greatly reduced, the sensitivity of sensitive skin to products can be reduced, and for local anesthesia application of small surgeries such as puncture on subsequent patients, the irritation feeling of the skin after being damaged to the applied local anesthesia medicine is reduced, and better compliance is achieved. The preparation process of the cream provided by the invention is simple and stable to operate, and can meet the requirements of industrial large-scale production.