29 results about "Nerve Blockade" patented technology

The invention relates to the technical field of medical image recognition, in particular to an ultrasound-guided nerve block liquid medicine diffusion image recognition method, which comprises the following steps of: dynamically analyzing a set with external expansion morphological feature points on a liquid medicine diffusion boundary to construct directional data representing a diffusion trend, and performing density statistics on the directional data to obtain an image recognition result; therefore, the dominant direction of liquid medicine diffusion in space is accurately identified, judgment is carried out in combination with the change trend of the dominant direction in a continuous time frame, a time slice with the stable and continuous direction is screened out, then the method goes deep into a liquid medicine coverage area, the consistency between the pixel gray scale gradient change and the nerve fiber anatomy trend is compared, and the accuracy of the nerve fiber anatomy is improved. Finally, effective classification of the diffusion paths is realized, an effective diffusion area conforming to the trend of the neural structure and a non-dominant diffusion area towards other tissues can be clearly distinguished, and the accuracy and clinical reference value of an identification result are greatly improved.

The invention provides a nerve block device for enhancing ultrasonic guided effective development, and belongs to the field of medical instruments. Comprising a fixing sleeve, the inner surface of the fixing sleeve is connected with a rack in a clamped mode, the outer surface of the lower end of the rack is fixedly connected with a probe, an adjusting assembly is arranged on the outer side of the fixing sleeve and comprises a mounting plate fixedly connected with the outer surface of the fixing sleeve, and the inner side of the mounting plate is detachably connected with a guide frame. By arranging the adjusting assembly, the puncture angle of the puncture tube can be accurately adjusted and controlled, so that a nerve blocking agent can be accurately injected to a proper part under ultrasonic guidance, and meanwhile, the guide frame can keep the position of the puncture tube stable; the device is simple in structure and convenient to use, puncture errors caused by hand movement of medical staff in the puncture process can be reduced, the puncture depth position is within a proper range, the puncture precision can be further improved, and then the blocking effect on nerves can be effectively guaranteed.

The invention discloses an ultrasonic image segmentation system training method and a nerve block auxiliary system, and belongs to the field of medical image segmentation, and the method comprises the steps: proposing a semi-supervised segmentation framework of progressive learning from simple to difficult, and explicitly generating a simplified sample and a complicated sample through the bidirectional replacement of a difficult region and a simple region, and a gradient weight mechanism is introduced, and the contribution strength of the two types of samples in each training stage is dynamically regulated and controlled. The nerve block auxiliary system comprises an ultrasonic device, a data acquisition device, a processing system and an interaction device, an ultrasonic image segmentation system trained by the provided method is deployed in the processing system, and the processing system is used for inputting a to-be-segmented ultrasonic image into the ultrasonic image segmentation system so as to carry out segmentation and visualization processing on the ultrasonic image. And the segmentation result and the visualization result are visually displayed through the interaction device. The segmentation performance of the ultrasonic image segmentation system can be improved, so that nerve block is effectively assisted.

The present invention discloses a nerve block simulation training method and related equipment. The method includes: constructing ultrasonic simulation models of different tissue parts of the human body based on standard three-dimensional anatomical structure information and simulated ultrasonic information of different tissue parts of the human body, and associating the ultrasonic simulation models of different tissue parts with the tissue simulator through coordinate information; tracking the relative position information and relative angle information of the simulated ultrasonic probe and the tissue simulator, and generating corresponding simulated ultrasonic images through the ultrasonic simulation model; tracking the position information and angle information of the simulated nerve block puncture needle in the tissue simulator, taking the intersection of the coordinate range of the puncture needle and the coordinate range of the simulated ultrasonic probe section, obtaining the coplanar coordinate range of the puncture needle and the simulated ultrasonic probe section, and converting the point-to-point into the simulated puncture needle ultrasonic image. It solves the problem that the simulated puncture site is limited, the clinical situation cannot be truly simulated, the efficiency of the transformation of simulation teaching to clinical practice is reduced, and the application value of actual clinical cases is lacking.

The utility model relates to the field of medical instruments, in particular to an ultrasound-guided nerve block puncture simulation teaching device. The device is composed of a nerve block puncture mechanism, a shell, an ultrasonic detection part and a feedback device. One side of the shell is an operation area for placing an ultrasonic detection part made of silica gel and scales, and the other side of the shell is a feedback area provided with a switch and a power supply. The puncture needle, the connecting tube and the injector form a puncture mechanism, the feedback device comprises a first guide wire, a second guide wire and an acousto-optic feedback part, the two guide wires conduct electricity through the puncture needle, and the T-shaped protective sleeve protects the joint. The device overcomes the problems that an operator is difficult to really understand the operation process and skills, the operation opportunity is limited, the clinical practice operation risk is high and the like in the traditional nerve block puncture teaching, enables the operator to carry out a large amount of practice exercises in a safe environment, and improves the operation skills.

The present invention discloses an ultrasound image display system for nerve block, comprising: a processor; a memory coupled to the processor; and instructions, the instructions being stored in the memory and executable by the processor to enable the system to perform the following operations: acquiring a first image including a needle body and a second image, wherein the second image is an image captured temporally after the first image; determining a first needle body portion in the second image corresponding to the needle body in the first image; determining whether a difference between the grayscale of the needle body in the first image and the first needle body portion is greater than a first threshold value; and displaying an angle adjustment prompt on the display if a difference between the grayscale of the needle body in the first image and the first needle body portion is greater than the first threshold value.

The invention discloses a nerve block postoperative rehabilitation training auxiliary device which comprises a rack, a handle, a main input shaft, a power conversion mechanism, an energy storage mechanism, a critical trigger mechanism and a power-assisted execution mechanism. The handle is vertically arranged on the rack in a sliding manner; the main input shaft is transversely and rotatably arranged on the rack; the power conversion mechanism is used for converting vertical sliding of the handle into one-way rotating motion of the main input shaft; the energy storage mechanism is used for storing mechanical energy when the main input shaft rotates unidirectionally and preventing the main input shaft from rotating reversely; the critical triggering mechanism is in linkage with the main input shaft and the energy storage mechanism and used for relieving reverse rotation prevention of the energy storage mechanism on the main input shaft when the handle moves to a preset critical position, and the assistance executing mechanism is connected with the main input shaft and used for applying upward assistance force to the handle when the main input shaft rotates reversely at a high speed. The nerve block postoperative rehabilitation training auxiliary device can provide instantaneous and accurate auxiliary rehabilitation training at the critical point where the nerve block postoperative rehabilitation training auxiliary device is most helpful.

The utility model discloses a combined radio frequency electrode, and relates to the technical field of medical instruments. The radio frequency thermal coagulation electrode integrates multiple functions of ultrasonic guidance, a temperature sensor, an impedance sensor, a nerve plexus stimulation needle, a radio frequency thermal coagulation electrode and the like. The radio frequency sleeve is composed of a needle tube, an insulating layer, a sleeve seat, a lock cap, a sheath and the like. And various head structures are provided for clinical selection. The radio frequency probe is composed of a sheath tube, an electrode wire, a probe seat, a color code tube, a wire and a plug. Wherein an ultrasonic guide mark is added at the front end of the probe, so that ultrasonic guide can be adopted when the radio frequency thermal coagulation electrode punctures and enters a target part of a human body, and the harm of ionizing radiation to a medical patient is avoided. The radio frequency sleeve and the probe are locked together through the locking sleeve seat and the probe seat. After the combined multifunctional radio frequency thermal coagulation electrode is connected with a radio frequency therapeutic apparatus, various operations such as temperature measurement, impedance measurement, electrical stimulation positioning, nerve blocking, radio frequency thermal coagulation and the like can be carried out.

Provided herein are methods for blocking nerves, for example, for treating obesity, heart failure, cardiovascular disease, muscle spasms, chronic pain, or urinary retention in postoperative patients. The methods can include first heating the nerve to a temperature above physiological temperature (e.g., human body temperature of 37°C), for example, in the range of 43°C to 54°C, for a period of time, which results in reversible nerve blockade, which is the opposite of nerve damage. Second, reversible nerve blockade can be produced by cooling the nerve to a temperature below physiological temperature, where reversible nerve blockade can be achieved, for example, in the range of 15°C to 30°C.

The application discloses a long-acting local anesthetic compound, a preparation method, application and a pharmaceutical composition thereof. The long-acting local anesthetic compound is prepared by the following steps: reacting a local anesthetic with bromoethanol to generate a quaternary ammonium salt intermediate, and then condensing the quaternary ammonium salt intermediate with a non-steroidal anti-inflammatory drug. The preparation method is simple and suitable for large-scale production. The prepared long-acting local anesthetic compound has a long duration and an anesthetic time of more than 24 hours, and has nerve block selectivity. The long-acting local anesthetic compound can reduce the frequency of administration, increase the compliance of patients, greatly reduce the risk of anesthesia, and has a very good application prospect.

The application provides a nerve block device capable of enhancing ultrasound-guided effective development, and belongs to the field of medical instruments. The device comprises a fixing sleeve, a rack is clamped and connected to the inner surface of the fixing sleeve, a probe is fixedly connected to the outer surface of the lower end of the rack, an adjusting assembly is arranged on the outer side of the fixing sleeve, the adjusting assembly comprises a mounting plate fixedly connected to the outer surface of the fixing sleeve, and a guide frame is detachably connected to the inner side of the mounting plate. The adjusting assembly can accurately adjust and control the puncture angle of the puncture tube, so that the nerve block agent can be accurately injected into the appropriate position under the guidance of ultrasound. Meanwhile, the guide frame can keep the position of the puncture tube stable, which helps to reduce the puncture error caused by the hand movement of medical staff during the puncture process, so that the puncture depth position is within the appropriate range, thereby further improving the puncture precision and effectively ensuring the nerve block effect.

The invention discloses an evaluation method and system for improving postoperative sleep of an elderly patient through nerve block analgesia, relates to the field of anesthesiology and pain management, and solves the problems that it is difficult to construct a staging model by using a CNN deep learning framework, and it is difficult to obtain multiple comprehensive indexes by recording data related to sleep quality in the whole night sleep period through PSG detection. The method comprises the following steps of: randomly dividing the elderly patients into a control group and an experimental group; carrying out a PSG test in a hospital sleep laboratory; constructing a staging model by using a CNN deep learning framework, and obtaining a sleep time comprehensive evaluation index, an awakening time continuous interval comprehensive index and a sleep respiration and limb disorder comprehensive index; the multiple indexes and the sleep efficiency are combined to obtain a comprehensive sleep quality evaluation index; and analyzing the sleep quality improvement condition according to the control group-experimental group comprehensive sleep quality proportion value.

Disclosed herein are systems and methods for performing a cardiac arrhythmia and a subsequent nerve block. A cryogenic device can be provided and can comprise a handle comprising a proximal end and a distal end, an elongate shaft extending from the handle, the elongate shaft comprising a lumen, a cryogenic probe extending from the elongate shaft, wherein the cryogenic probe is flexible, and an adapter removably located at a distal end of the elongate shaft, the adapter comprising a base portion, a head portion, and an opening therethrough, wherein the base portion comprises one or more prongs configured to key onto the elongate shaft, wherein the head portion is rounded and comprises a groove embedded within. The adapter can be configured to receive the cryogenic probe via the opening and within the groove such that the cryogenic probe maintains a shape when coupled to the groove.

Systems for nerve and tissue modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be positioned or moveable to target a particular target region. The nerve modulation element may be an ultrasound transducer. The nerve modulation element may be configured to be operated at a low intensity to provide a thermal nerve block or a high intensity to effect tissue modulation.

Systems for nerve and tissue modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be positioned or moveable to target a particular target region. The nerve modulation element may be an ultrasound transducer. The nerve modulation element may be configured to be operated at a low intensity to provide a thermal nerve block or a high intensity to effect tissue modulation.

The invention provides a nerve block puncture needle and a guiding device thereof. The guiding device comprises a bottom plate, two parallel sliding grooves with opposite openings are fixed to the top face of the bottom plate, an ultrasonic detection opening is formed in the area between the two sliding grooves, and a puncture needle guiding hole is formed in the position close to the end of the ultrasonic detection opening; the probe positioning assembly comprises a containing frame with the bottom located in the ultrasonic detection opening and sliding strips installed on the two sides of the containing frame, the containing frame is used for being inserted into the front end of the ultrasonic probe, and the sliding strips are arranged in the sliding grooves in a sliding mode. The puncture needle comprises a puncture needle body and the guide device, and the needle head of the puncture needle body can penetrate through the puncture needle guide hole. Reflection rings are arranged on the puncture needle body at intervals, and a reflection block with a plurality of inclined faces is arranged on the needle point part. The distance between the ultrasonic probe and the puncture needle can be conveniently adjusted, the puncture needle of a specific structure is arranged, and therefore the developing effect of nerve block puncture under ultrasonic guidance is ensured.

Accelerated recovery from direct current (DC) nerve block can be achieved using repolarization. A direct current (DC) waveform can be applied to a nerve for a time sufficient to achieve nerve block. The DC waveform can be switched to another DC waveform of reversed polarity, which can be applied for a second time, causing the nerve to enter a repolarization cycle to accelerate recovery time for the nerve. Moreover, simply applying a subthreshold DC waveform to the nerve for a time by itself can enhance a response of the nerve without blocking conduction in the nerve.

The application discloses a combined multifunctional radio frequency heat condensation electrode, and relates to the technical field of medical devices.The radio frequency heat condensation electrode integrates ultrasonic guidance, temperature sensors, impedance sensors, nerve plexus stimulation needles, radio frequency heat condensation electrodes and other functions.The radio frequency heat condensation electrode is composed of a needle tube, an insulating layer, a sleeve seat, a lock cap, a sheath and the like; and various head structures are provided for clinical selection.The radio frequency probe is composed of a sheath tube, an electrode wire, a probe seat, a color code tube, a lead wire and a plug; an ultrasonic guidance mark is added to the front end of the probe, so that the radio frequency heat condensation electrode can be guided by ultrasonic waves when puncturing into a target site of a human body, and thus the harm of ionizing radiation to a patient is avoided.The radio frequency sleeve and the probe are locked together through the locking sleeve seat and the probe seat, and the combined multifunctional radio frequency heat condensation electrode can perform temperature measurement, impedance measurement, electric stimulation positioning, nerve block, radio frequency heat condensation and other operations after being connected with a radio frequency therapeutic instrument.

This invention discloses an N-acetanilide cationic compound, its preparation method, and its applications, particularly in the pharmaceutical field. This cationic compound exhibits rapid onset of action, high potency, long duration of action, good safety profile, and strong nerve-blocking effect. It can exert a reversible and sustained local anesthetic effect in vivo and can be used as a long-acting and / or selectively blocking local anesthetic or analgesic, showing great promise and value.

The invention discloses a nerve block simulation training method, head-mounted display equipment and a storage medium, and relates to the technical field of virtual reality, the disclosed nerve block simulation training method comprises the following steps: acquiring an image of a to-be-trained nerve block part, and constructing a virtual model of the to-be-trained nerve block part according to the image; the virtual model is displayed on a display screen of the head-mounted display device, and the anatomical mark and the needle inserting path are displayed on the virtual model in an overlapped mode; on the display screen, displaying an operation result after the puncture needle performs needle insertion operation based on the anatomical mark and the needle insertion path, the operation result including a puncture angle, a needle insertion depth and an ultrasonic image matching degree; according to the puncture angle, the needle insertion depth and the ultrasonic image matching degree, the operation score of the to-be-trained nerve block part is obtained, the problem that the nerve block training is difficult to meet the clinical actual demand is solved, the nerve block training effect is improved, and the nerve block training can meet the clinical actual demand.

The invention discloses an ultrasound-guided nerve block puncture needle and a medicine injection method thereof, and relates to the technical field of medical instruments, the ultrasound-guided nerve block puncture needle comprises a needle tube, a needle head arranged at one end of the needle tube, a needle core arranged in the needle tube, and a liquid guide tube arranged on the needle tube and communicated with the needle tube, a substrate layer for improving the echo intensity is arranged on the needle head, a microarray structure for expanding the effective reflection area is arranged on the substrate layer, a polymer packaging layer is arranged on the microarray structure, a strong ultrasonic echo basis can be provided by arranging the substrate layer, the microarray structure is arranged on the substrate layer, and the ultrasonic echo intensity can be improved by arranging the polymer packaging layer on the substrate layer. A clear image of the whole side wall of the puncture needle can be reconstructed by ultrasonic equipment, the fragile microstructure can be protected by arranging the polymer packaging layer, the acoustic conversion process is further optimized by selecting a polymer material with proper acoustic impedance, and meanwhile friction is reduced.

An ultrasonic imaging device and an ultrasonic imaging method, the device comprising a transmitting and receiving circuit, an ultrasonic probe, a processor, and a display, wherein the transmitting and receiving circuit controls the ultrasonic probe to transmit a first ultrasonic wave to a portion of a target object where nerve block is to be performed in a grayscale imaging mode; the processor generates an ultrasonic image of the portion where nerve block is to be performed based on the first ultrasonic echo data, identifies a neurovascular region in the ultrasonic image, and obtains the position of a sampling frame including the neurovascular region; the transmitting and receiving circuit also controls the ultrasonic probe to transmit a second ultrasonic wave to the position of the sampling frame in a Doppler imaging mode; the processor also obtains blood flow information based on the second ultrasonic echo data, obtains a vascular region in the ultrasonic image based on the blood flow information, obtains a nerve region in the ultrasonic image based on the neurovascular region and the vascular region, and controls the display to display the ultrasonic image, wherein the nerve region and the vascular region are highlighted so as to be distinguishable from each other on the ultrasonic image.

The invention relates to the technical field of probe supporting hand racks, and discloses a multifunctional probe supporting hand rack for nerve block under the guidance of B ultrasound. Comprising a base, a sliding plate is fixedly connected to the upper surface of the base, a movable seat is slidably connected to the interior of the sliding plate, supporting plates are fixedly connected to the two sides of the movable seat, movable plates are movably connected to the upper surfaces of the supporting plates through shaft rods, and balls are movably connected to the rear surfaces of the movable plates; according to the invention, the connection between the ball and the movable plate is utilized, so that the spherical connection between the ball and the movable plate allows the probe to rotate and position in multiple directions, and the movable plate realizes the pitching angle adjustment through the hinge structure of the shaft rod and the support plate; the rubber plate absorbs vibration during operation through the first connecting block and the second connecting block to prevent the probe from shifting, so that the stability and accuracy of images are ensured when the B ultrasound guides the nerve block, the accuracy and repeatability of the nerve block are improved, and the operation fatigue of medical staff is reduced.

Nerve stimulation via a Low Frequency Alternating Current (LFAC) waveform can result in blocking of action potential conduction, while an increase in LFAC frequency and / or amplitude can translate into nerve activation. As LFAC for nerve blocking is frequency independent, the threshold LFAC activation can decrease with increasing frequency. Thus, frequency and amplitude settings can determine whether LFAC activates or blocks nerve fibers. LFAC can also be orderly, wherein smaller, non-fatiguing nerve fibers can be activated before larger nerve fibers. LFAC settings for activation can also be influenced by the configuration of a cuff assembly that positions an electrode along a nerve. The cuff can position a nerve in a cuff through hole, and a sliding closure of the cuff can be slide into a radial opening to substantially lock the nerve in the cuff assembly. An electrode material is positioned within a window of the cuff and is connected to an electrical lead. An interface coating on a nerve-facing bioelectric surface of an electrode material, and related compositions and methods, are also provided.

The invention relates to a sugammadex sodium / tetraphenyl vinyl pyridinium salt inclusion compound as well as a preparation method and application thereof. Comprising the following steps: synthesizing a tetraphenyl vinyl pyridinium derivative, assembling the tetraphenyl vinyl pyridinium derivative and sugammadex sodium in water or a phosphoric acid buffer solution through hydrophobic interaction and electrostatic interaction to form an inclusion compound with a bonding ratio of 2: 1, and performing red shift on fluorescence emission from 555 nm to 600 nm. The preparation method is simple and pollution-free. The clathrate compound has remarkable ratio fluorescence change on nerve blocking agents such as rocuronium bromide, vecuronium bromide and pantocuronium bromide, fluorescence emission is blue-shifted from 600 nm to 555 nm, the clathrate compound is suitable for high-sensitivity detection of positive charge nerve blocking agents, and the sensitivity of the clathrate compound reaches the nanomole level. The supramolecular host-guest clathrate compound provides an efficient way for high-sensitivity detection of a nerve blocking agent.

This invention discloses a method and system for nerve block puncture needles based on dynamic changes in injection pressure, relating to the field of medical device control technology. During operation, the system collects pressure data sequences at a preset sampling frequency using an intra-needle pressure sensor. These sequences are then smoothed using low-pass filtering and a fixed sampling window to obtain a stable pressure data sequence that characterizes the continuous pressure change trend and reduces high-frequency interference. Based on the stable pressure data sequence, the pressure change rate and pressure change acceleration are calculated and jointly analyzed within the continuous sampling time interval. When the pressure change rate changes from positive to negative and exceeds a first preset threshold, and the pressure change acceleration experiences an extreme value change and exceeds a second preset threshold, fascial breakthrough is determined. The needle tip advancement speed is graded and adjusted according to the pressure change rate trend, and continuous and intermittent advancement are used to control the needle tip displacement. Real-time pressure data is compared with the target pressure range and pressure fluctuation range; when deviations occur, a needle tip position adjustment command is generated and a prompt signal is output.

The utility model provides a nerve block injection pump, and belongs to the technical field of nerve block operation auxiliary equipment. The problem that the nerve block injection pump is poor in flexibility and adaptability due to the fact that the nerve block injection pump cannot be well matched with syringes which are different in size specification is solved. The nerve block injection pump comprises an injection pump shell, an injector fixing unit, a lead screw transmission unit and a push-pull execution unit. The injector fixing unit comprises a V-shaped base and a length fixing module, the V-shaped base fixes an injector, the length fixing module clamps the injector through a sliding length clamping block and a baffle, a sliding block slides along the axis of the injector, and a pushing block of the push-pull execution unit is fixed to the sliding block and pushes a piston rod of the injector to complete medicine injection. By means of the arrangement, the nerve block injection pump can be matched with injectors of different sizes and specifications, and the problem that the nerve block injection pump is poor in flexibility and adaptability is solved.