29 results about "Nerve conduction" patented technology

Apparatus and methods for deactivating bronchial nerves and ablating smooth muscle extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits ultrasound so as to heat tissues throughout a relatively large impact volume (13) to a temperature sufficient to inactivate nerve conduction and ablate smooth muscle but insufficient to cause rapid ablation or necrosis of the surrounding tissues. The treatment can be performed without locating or focusing on individual bronchial nerves or smooth muscle.

The embodiment of the invention discloses a brain operation path determination method and device, equipment, a medium and a medical system. The brain operation path determination method comprises the steps that a brain structure model and at least one target spot of a target user are obtained; based on the brain structure model, determining an information transfer relationship between each nuclear group sub-model and each nerve fiber sub-model; determining a plurality of candidate operation schemes based on the plurality of preset path starting points, the target group sub-model to which the at least one target point belongs and the information transfer relationship; for each candidate operation plan, performing quality evaluation on the candidate operation plan based on a quantitative evaluation model under at least one evaluation dimension, and determining a path quality attribute corresponding to each candidate operation plan; according to the method, at least one target recommended operation scheme is determined based on each path quality attribute, a plurality of candidate paths conforming to nerve conduction characteristics are automatically generated, and an optimal scheme is screened through a quantitative evaluation model, so that the brain tissue injury risk and the operation complexity are effectively reduced while the operation precision is improved.

The invention provides a sound wave and low-frequency pulse collaborative sleep-aiding oxygen cabin control method, which comprises the following steps of: setting a basic period stage of an oxygen cabin on the basis of a superdaily rhythm of a human body sleep period, and determining a core physiological target of the basic period stage; respectively carrying out time sequence matching of low-frequency pulse, sound wave stimulation and oxygen supply pressurization; carrying out nerve conduction path matching and organ response space-time synchronization based on the corresponding organ nerve induction partitions; establishing a fuzzy control model, performing multi-parameter real-time detection, and dynamically adjusting modal parameters according to monitoring data of human body physiological indexes; setting a pulse intensity upper limit, a sound wave decibel upper limit, an oxygen concentration upper limit and a single pressurization duration, and executing oxygen cabin operation control according to the modal parameters. The method has the advantages in physiological adaptation, collaborative accuracy, individual adaptation and safety guarantee, fits the electroencephalogram and physiological law of natural sleep, and improves the sleep continuity.

The invention provides an electronic whiteboard teaching display method, system and device and a storage medium, and the method comprises the steps: obtaining multi-modal image data, and generating a human body three-dimensional model according to the multi-modal image data; acquiring an endoscope frame picture, extracting key feature points of the endoscope frame picture, automatically matching the human body three-dimensional model according to the key feature points, and determining a target organ corresponding to the endoscope frame picture; generating an organ contour perspective view corresponding to the target organ and a nerve conduction path map corresponding to the position of the target organ based on the human body three-dimensional model; and superposing the organ contour perspective view and the nerve conduction path diagram to the endoscope frame picture through an electronic whiteboard for display. According to the invention, a real endoscope picture is combined with the virtual model, an interactive operation teaching platform with intelligent virtual-real fusion capability is constructed, and the operation teaching effect is improved.

The application discloses a robot social behavior control method based on comprehensive evaluation and optimal control principles, and the method comprises the following steps: collecting external multi-modal information, making a comprehensive decision on a social object, modeling a robot eye-head actuator, solving a motion trajectory with minimum nerve conduction noise, and performing optimal control by using an MPC controller to realize parallel interaction between the robot and multiple social objects. The optimal control is performed on the robot to generate human-like motion and gaze effects.

The invention relates to the technical field of medical health informatics, in particular to a myopia early warning method and device, a storage medium and electronic equipment. The method comprises the following steps: statically acquiring periorbital heat distribution gradient and nerve response time delay data to construct an individualized baseline model by wearing equipment integrated with a thermal sensor and a nerve conduction membrane on the face of a user; dynamically monitoring thermal field deviation, nerve conduction change and myoelectricity disturbance in the visual cognition task; a multi-dimensional risk index is calculated in combination with a dynamic deviation mapping algorithm and an adaptive weight distribution model, a myopia-induced fatigue risk level is predicted, and a personalized intervention strategy is matched according to user portrait features to realize closed-loop early warning and intervention optimization. According to the myopia early warning system and method, the physiological signals and the behavior data are collected in real time for synchronous analysis, data processing and early warning decision are executed in combination with the electronic equipment and the storage medium, and the accuracy and intervention adaptation degree of myopia early warning are effectively improved.

The invention discloses a compound with a local anesthesia function as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The preparation method of the compound comprises the following steps: mixing and heating lidocaine and 2-bromoethanol to obtain a compound 1; the preparation method comprises the following steps: mixing dicarboxylic acid, N-hydroxysuccinimide, 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride and a solvent to obtain a mixed solution; mixing and dissolving a compound 1, alkali and a solvent, and then adding into the mixed solution; and then carrying out spin-drying, separation and purification to obtain the compound with the local anesthesia function. The medicine can be used as a local anesthetic or analgesic for long-acting nerve block or selective nerve block. The medicine can block nerve conduction, has biocompatibility and biodegradability, is expected to overcome the problems of short time efficiency of single-needle injection and the like, and improves the efficacy of the medicine.

The invention discloses a binocular modulation difference-based visual stabilization method, and particularly relates to the technical field of biomedical engineering, and the method comprises the following steps: S1, binocular neural signal conduction delay data acquisition, S2, visual stability adaptive time difference threshold setting, S3, near-infrared light parameter and conduction velocity association relationship establishment, S4, binocular near-infrared light parameter combination screening, and S5, visual stability adaptive time difference threshold setting. And S5, calibrating double-path driving delay parameters. According to the method, a time difference threshold interval is set in combination with a visual phase difference physiological adaptation range, the incidence relation between the near-infrared light parameters and the nerve conduction velocity is established, parameter setting is deeply fused through binocular nerve conduction delay data and cortical neuron response time sequence data, the adaptability of the parameters and the nerve physiological state is enhanced, and the accuracy of the nerve physiological state is improved. The collaborative accuracy of near-infrared light modulation parameters of the two eyes is improved, it is ensured that the time sequence of the two-way driving signals is accurately matched with a nerve regulation target needed by visual stability, and the problem that the visual regulation effect is poor due to parameter setting deviation is solved.

Apparatus and methods for deactivating bronchial nerves extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits focused ultrasound so as to heat tissues throughout circular impact volume (13) as, for example, at least about 1 cm3 encompassing the bronchus to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual bronchial nerves.

This invention relates to the field of blood drawing nursing technology, specifically a blood drawing nursing device to reduce psychological resistance. It includes a partition with a display screen embedded inside. An airbag A is installed inside the partition, and an air pump is connected to one side of airbag A. A support plate is connected to one side of the partition, and a grip ring is fixedly connected to the upper end of the support plate. Guide grooves are installed on both sides of the support plate, and cooling plates slide inside both sets of guide grooves. An airbag B is fixedly connected to the outside of the grip ring. This invention generates continuous tactile stimulation by the reciprocating motion of the cooling plates on both sides of the arm. This physical stimulation, through nerve conduction, distracts the brain's attention, reducing the pain of needle insertion and lowering the patient's sensitivity to pain. Simultaneously, the partition and the display screen block the patient's direct line of sight to the needle and puncture site, preventing fainting and tension caused by visual stimulation, thus keeping the patient relaxed during the blood drawing process.

The invention relates to the field of intelligent medical treatment, in particular to an eye disease prediction method and device based on monochromatic light and a program product. Comprising obtaining a monochromatic background light source; the monochromatic background light source flickers at a frequency to perceive the retina of the subject to obtain perceived data; performing eye disease judgment based on the sensing data of the monochromatic light source, when the background light source is red and the sensing data is smaller than a red preset threshold value, predicting that the visual cone cells in the macular region are abnormal, otherwise, predicting that the visual cone cells are normal; when the background light source is green and the sensing data is smaller than a green preset threshold value, determining that the optic nerve conduction of the vertebral body is abnormal, otherwise, determining that the optic nerve conduction is normal; and when the background light source is a yellow light source and the sensing data is smaller than a yellow preset threshold, judging that the retina and the optic nerve are abnormal, otherwise, judging that the retina and the optic nerve are normal. Eye anomaly prediction can be carried out through the monochromatic light source, and the method has good clinical value.

The present application relates to the technical field of medical health informatics, in particular to a myopia early warning method and device, a storage medium and an electronic device; the method comprises the following steps: through wearing a device integrating a thermal sensor and a nerve conduction film on the face of a user, static acquisition of eye thermal distribution gradient and nerve response time delay data is used to construct an individualized baseline model; dynamic monitoring of thermal field deviation, nerve conduction change and electromyographic disturbance in visual cognitive tasks; combination of a dynamic deviation mapping algorithm and an adaptive weight distribution model to calculate a multi-dimensional risk index, prediction of a myopia-induced fatigue risk level, and matching of a personalized intervention strategy according to user portrait characteristics, to realize closed-loop early warning and intervention optimization. The present application synchronously analyzes physiological signals and behavior data through real-time acquisition, and executes data processing and early warning decision-making in combination with an electronic device and a storage medium, thereby effectively improving the accuracy of early myopia warning and the intervention adaptation degree.

Apparatus and methods for deactivating renal nerves extending along a renal artery of a mammalian subject to treat hypertension and related conditions. An ultrasonic transducer (30) is inserted into the renal artery (10) as, for example, by advancing the distal end of a catheter (18) bearing the transducer into the renal artery. The ultrasonic transducer emits unfocused ultrasound so as to heat tissues throughout a relatively large impact volume (11) as, for example, at least about 0.5 cm3 encompassing the renal artery to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual renal nerves.

Apparatus and methods for deactivating bronchial nerves extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits focused ultrasound so as to heat tissues throughout circular impact volume (13) as, for example, at least about 1 cm3 encompassing the bronchus to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual bronchial nerves.

The invention relates to a pneumatic artificial muscle nerve teaching model and system, which are combined with a pneumatic artificial muscle nerve teaching model technology and adopt an aluminum alloy frame and a 3D printing bone surface model to construct a limb structure. The system receives an instruction through the voice recognition module, the Arduino controller coordinates the LED lamp strip display system and the dual-motor driving system, and nerve conduction path visualization and joint precise control are achieved. Innovation points comprise multi-mode interaction, pathological phenomenon quantitative simulation (folding knife phenomenon / spasm / ankylosis), muscular tension grading and safety mechanism design. The application scene covers basic anatomy teaching, neuroscience learning, rehabilitation training and clinical skill assessment, supports Ashworth grading comparison and upper motor neuron injury simulation, improves teaching immersion and clinical association ability, and has the characteristics of modular design, convenience in maintenance and upgrading, safety and reliability.

The invention discloses application of hecogyin and pharmaceutically acceptable salts thereof in preparation of drugs for treating spinal cord injury. The hecogenin and the pharmaceutically acceptable salt thereof have an obvious effect of promoting spinal cord nerve repair, can improve nerve conduction disorder and motor function loss of a mouse with spinal cord injury, are helpful to recover normal physiological functions of an injured spinal cord area, and are expected to be developed into a new medicine for treating spinal cord injury.

The invention provides a health assessment method and device based on meridian information, and the method comprises the steps: collecting the nerve segment information of a target object, and carrying out the calculation to obtain a nerve conduction gain value; monitoring the conduction value of the meridian well point of the target object, and calculating to obtain the conduction variability of the meridian point; obtaining an interstitial fluid ratio of the target object, and calculating to obtain energy quotient decrement; performing weighted calculation on the basis of the nerve conduction gain value, the acupoint conduction variability and the energy quotient decrement to obtain a meridian function index; and evaluating the health state of the target object according to the meridian function index to generate an evaluation result. The nerve conduction gain value, the acupoint conduction variability and the energy quotient decrement data are comprehensively utilized, the meridian function index capable of evaluating the health state of the target object is obtained through weighted calculation, the accuracy of health evaluation is improved, the target object can be autonomously monitored at home, the monitoring efficiency is high, and the overall experience and satisfaction degree of a user are improved.

The invention relates to a pelvic floor sacral nerve double-position combined magnetic stimulation method and system, and the method comprises the steps: selecting a sitting position or lying position stimulation position according to a treatment target; positioning stimulation targets of pelvic floor muscles or sacral nerves according to the selected stimulation body position; initial magnetic stimulation parameters are set, and magnetic stimulation is applied to the positioned stimulation target; monitoring a motor evoked potential signal in the stimulation process; automatically calculating nerve conduction time according to the motor evoked potential signal; and dynamically adjusting at least one of subsequently applied magnetic stimulation parameters and stimulation target positions based on the nerve conduction time so as to achieve the purpose of pelvic floor and sacral nerve multi-target adaptive collaborative magnetic stimulation treatment based on nerve electrophysiological feedback.

The invention discloses application of glabridin and pharmaceutically acceptable salts thereof in preparation of drugs for treating spinal cord injury. The glabridin and the pharmaceutically acceptable salt thereof have an obvious effect of promoting spinal cord nerve repair, can improve nerve conduction disorder and motor function loss of a mouse with spinal cord injury, are helpful to recover normal physiological functions of an injured spinal cord area, and are expected to be developed into a new medicine for treating spinal cord injury.

The application provides application of flufenamic acid in preparation of a medicine for treating peripheral nerve adhesion diseases, and relates to the technical field of biomedicine, and the technical scheme is characterized in that: application of flufenamic acid (2-(3-trifluoromethyl anilino) benzoic acid) in preparation of a medicine for treating peripheral nerve adhesion diseases, the peripheral nerve adhesion diseases including sciatic nerve adhesion. The application provides application of flufenamic acid in preparation of a medicine for treating peripheral nerve adhesion diseases, and the application proves that 2-(3-trifluoromethyl anilino) benzoic acid (flufenamic acid, FFA, CAS: 530-78-9) can effectively promote the motor balance ability and nerve conduction rate of a mouse, promote recovery of adhesion nerves, and has a positive treatment effect on peripheral nerve adhesion diseases.

The utility model discloses an intelligent knee joint rehabilitation brace which comprises a fixing brace composed of an upper frame, a lower frame and a joint limiter, the upper end and the lower end of the joint limiter are fixed to the outer end of the upper frame and the outer end of the lower frame respectively, and a heating component, an electrotherapy component and a control component are arranged on the fixing brace. The control part is fixed on the joint limiter, and the heating part and the electrotherapy part are electrically connected with the control part; the fixing brace is simple in structure and convenient and fast to use, the heating component and the electrotherapy component are arranged on the fixing brace, hot compress and electrotherapy stimulation effects can be effectively carried out on the legs of a patient, the blood circulation effect is improved, the pain and swelling conditions are relieved, the electrode slices can stimulate the responding leg acupuncture points, and the pain and swelling of the patient is relieved. The knee joint rehabilitation training device has the advantages that muscle contraction and nerve conduction are promoted, muscle strength is enhanced, leg rehabilitation is promoted, a gyroscope is matched, the knee joint bending condition of a patient can be recorded, and a more complete rehabilitation treatment process is formulated.

The invention belongs to the technical field of dysphagia assessment, and particularly relates to an assessment system for treating myasthenia gravis complicated with dysphagia. According to the method, comprehensive analysis of nerve conduction, muscle fatigue and rhythm coordination is achieved by fusing multi-source information, compared with a single signal analysis mode, the evaluation result is more comprehensive and accurate, a dynamic weight module is introduced, the disease course stage of a patient is combined with rhythm deviation, swallowing evaluation parameters are weighted and corrected in real time, and the evaluation accuracy is improved. The timeliness and individualized precision of an evaluation result are effectively improved, the swallowing classification module can automatically identify swallowing disorder types caused by different pathological mechanisms based on key indexes such as nerve conduction delay, fatigue characteristics and dynamic weights, and the system can continuously monitor the state of a patient through combination of the resting data module and the swallowing evaluation module, so that the system can be used for evaluating the state of the patient. Quantitative tracking of the swallowing function is achieved, a dynamic evaluation basis is provided for doctors, and the doctors can be assisted in making personalized rehabilitation plans.

The application provides application of benzene sulfonamide in preparation of a medicine for treating peripheral nerve adhesion diseases, and relates to the biomedical technical field, and has the technical scheme as follows: the application of benzene sulfonamide in preparation of the medicine for treating peripheral nerve adhesion diseases, and the application is proved through specific verification experiments, specifically, the application systematically evaluates the influence of benzene sulfonamide on mouse nerve adhesion through various technical means such as direct observation on nerve adhesion and muscle atrophy, electrophysiological recording and behavior test, and successfully proves the positive effect of benzene sulfonamide on promoting recovery of adhesion nerves, improving motor balance ability and improving nerve conduction rate. These research results not only provide a solid scientific basis for benzene sulfonamide as a potential therapeutic drug, but also open up a new research direction for the treatment of peripheral nerve adhesion diseases.

The present application relates to the technical field of nerve electrophysiological examination data processing, in particular to a method and system for nerve conduction examination data interpretation and diagnosis, first performing field extraction, term standardization and other preprocessing on the examination data to obtain a detection item set, performing pre-determination through a preset 15-class peripheral nerve injury disease diagnosis rule base, directly outputting results and determination basis if the diagnosis rule is met, and entering a model interpretation process if not; based on nerve conduction anatomy prior recognition, pairing relationship is identified and contrast features are generated, a direction consistent deviation matrix is constructed in combination with normal population data; multi-dimensional features are fused and a nerve conduction anatomy relationship graph is constructed, a relationship perception heterogeneous graph attention network coding is used by introducing edge type embedding, global features are extracted through contrast perception attention pooling enhanced by pairing difference to realize disease classification. The present application can improve interpretation efficiency and accuracy, reduce subjective errors, and provide objective auxiliary diagnosis support for neuromuscular diseases.

The invention provides a method for generating resonance to virtuous circle of brain cell functions through angle correction of same-frequency equipment, and relates to the technical field of brain function adjustment and audio equipment application. According to the method, on the basis of a music hall sound field framework design rule, through accurate correction of sound field angles of multiple groups of same-frequency audio units, a directional resonance sound field is constructed, so that the resonance frequency is matched with specific brain waves in a same-frequency mode, the activity of brain nerve cells is stimulated, secretion of dopamine and serotonin in the brain is promoted, and the virtuous circle of brain cell metabolism and nerve conduction is achieved. The problems that a traditional audio device is dispersed in sound field and low in resonance efficiency are solved through angle correction, the brain cell activity can be improved by 15%-30% through directional resonance, the anxiety emotion is relieved, the attention concentration degree is improved, and the device is suitable for family health care, rehabilitation assistance, learning efficiency improvement and other scenes and has the advantages of being easy and convenient to operate, high in adaptability and free of side effects.

Apparatus and methods for deactivating bronchial nerves extending along a bronchial branch of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the bronchial section to be treated. The ultrasonic transducer emits focused ultrasound so as to heat tissues throughout circular impact volume (13) as, for example, at least about 1 cm3 encompassing the bronchus to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual bronchial nerves.

The invention provides a processing system based on electroencephalogram feedback, which comprises a signal processing and calculating module, and the signal processing and calculating module comprises a time synchronization unit and a feature extraction unit, and is used for extracting event-related potential components induced by each electrical stimulation pulse from electroencephalogram signals collected in a target stimulation period, the peak moment of each event related potential component is determined; the nerve conduction time calculation unit is used for calculating the average nerve conduction time of all the electrical stimulation pulses and the average amplitude of all the event-related potential components in the target stimulation period according to the emission time of each electrical stimulation pulse and the peak time of the corresponding event-related potential component; and the path state evaluation unit is used for calculating a period evaluation value of the target stimulation period according to the average nerve conduction time and the average amplitude. According to the invention, fusion evaluation between the electrical stimulation pulse and the evoked electroencephalogram response is realized.

The invention discloses a multi-mode pain sense conduction path intelligent interaction demonstration system and a construction method thereof, and relates to the technical field of biomedicine teaching demonstration equipment. In order to solve the defects that an existing pain sense demonstration device is in a static demonstration mode and cannot dynamically restore various pathological features, multi-source commands are prone to preempting conflicts, adaptation is tedious due to hardware parameter hard coding, and cross-scene expansion and maintenance cost is high, a brain region model, a trunk model, a stomach model and a nervous system model are fixed to a human skeleton model; the nervous system model is used for displaying a nerve conduction path so as to simulate a pain transmission path; the interaction module is used for inputting a control signal so as to control the nervous system model to display a corresponding nerve conduction pathway; the driving module is used for receiving a control signal of the interaction module; the driving module is used for displaying a corresponding nerve conduction path; the scheduling module is used for responding to a plurality of scheduling instructions according to a preset priority. The device is mainly used for intelligently demonstrating the multi-mode pain sense conduction pathway.

The present invention relates to a nerve conduit system for connecting two nerve ends end-to-end. In particular, the present invention relates to a nerve conduit system that supports the repair of nerve injuries by facilitating proper placement and orientation of the nerve ends and allowing the connection of nerve ends having the same or different diameters. Accordingly, a nerve conduit system (10) for connecting two nerve ends end-to-end is provided. The nerve conduction system (10) comprises a first portion (12) and a second portion (14), each portion (12, 14) having an insertion portion (16, 26) adapted to receive one of two nerve ends and a connection portion (22, 24), each portion (12, 14) including through holes (20, 30) defined by at least the respective insertion portion (16, 26) and extending between the longitudinally opposing ends of the respective portion (12, 14), the connection portions (22, 24) configured to engage with each other and arranged such that in a connected state, i.e., when the connection portions (22, 24) of the first portion (12) and the second portion (14) are engaged, the through holes (20, 30) are in fluid communication with each other.