691results about "Diagnostics using pressure" patented technology

Aspects of the present disclosure are presented for a surgical instrument having one or more sensors at or a near an end effector and configured to aide in the detection of tissues and other materials and structures at a surgical site. The detections may then be used to aide in the placement of the end effector and to confirm which objects to operate on, or alternatively, to avoid. Examples of sensors include laser sensors used to employ Doppler shift principles to detect movement of objects at the surgical site, such as blood cells; resistance sensors to detect the presence of metal; monochromatic light sources that allow for different levels of absorption from different types of substances present at the surgical site, and near infrared spectrometers with small form factors.

A probe device for use in non-invasive optical measurements of at least one parameter of the patient's blood. The probe device comprises a finger holder in the form of a clip member that secures a fingertip between its clamping legs. The probe device supports a measuring unit for applying optical measurements to a measurement location on the finger and carries a pressurizing assembly operable for applying controllably variable, substantially under-systolic pressure to the finger in the vicinity of the measurement location. Several measurement sessions are performed at the measurement location with at least two different 3 wavelength of incident light to detect light response of the medium and generate measured data indicative thereof, and the pressure applied to the vicinity of the measurement location is simultaneously varied during measurements. The light response of the medium corresponding to different wavelength of the incident light and different pressure values during measurements. The light response of the medium corresponding to different wavelength of the incident light and different pressure values is analyzed, and an optimal pressure value is determined, so as to utilize the corresponding light response of the medium for deriving therefrom the at least on blood parameter.

An optical measurement device and method are presented for use in non-invasive measurements on a patient's body. The device comprises an illumination assembly configured and operable to generate illuminating light of a predetermined wavelength range; a detection assembly; and a light directing assembly. The detection assembly comprises a first detector unit for detecting a first light signal transmitted through an illuminated body portion and generating first measured data indicative of the detected transmitted light, and a second detector unit for detecting a second light signal reflected from the illuminated body portion and generating second measured data indicative of the detected reflected light. The light directing assembly comprises a light diffuser for scattering back light incident thereto, to thereby direct the illuminating light or the light coming from the body portion back towards the body portion. This technique provides for increasing the amount of light reaching a region of interest inside the body portion and maximizing homogeneity of the first and second detected light signals.

A method for motion estimation within biological tissue is disclosed. The method involves acoustically coupling a transducer to a target biological tissue, which transducer emits an ultrasonic signal and collects the energy back-scattered by the target issue. A first set of energy data is collected and stored, then target tissue is axially compressed and a second set of ultrasonic energy data is collected and stored. One of the first and second data sets is warped to account for the anticipated compression forming a warped data set. This warped data set is cross-correlated with the unwarped one of the first and said second data sets to obtain a fine scale displacement of said target biological tissue from the displacement estimated by the warping. This fine scale displacement is summed with the warped data set to obtain a total axial displacement. A gradient of the total axial displacement is taken and used to form a strain image. An apparatus for practicing this method is also disclosed.

A method and system for measuring time variations of a response of a blood perfused fleshy medium to an external electromagnetic field is provided. The response of the medium to the external electromagnetic field can be a photo-acoustic signal, obtained in response to the exciting light, and/or impedance of the medium, in response to the applied ac electromagnetic field. Measurements of the time variations of the response of the medium are carried out when the condition of artificial kinetics is created and maintained over a certain time period by applying primary over-systolic pressure to a certain location at the medium with normal blood flow, so as to achieve a state of temporary blood flow cessation at the medium downstream of the certain location. When required, the control of the condition of the artificial kinetics can be further achieved by applying a perturbation of secondary pressure to the fleshy medium.

A remote palpation technique in breast imaging involves the use of multiple applications of radiation force in rapid succession throughout a two-dimensional plane in the target tissue medium (10), and combination of the small, two-dimensional displacement maps from each force location into a single, larger remote palpation image (block 43). Apparatus for carrying out the foregoing method is also disclosed.

An apparatus and method for determination of change in volume of a body part or body organ on a real-time basis. In a breastfeeding application, an inflatable cuff is positioned on a nursing breast and allows direct access to the nipple by the breastfeeding infant. The inflatable cuff includes an outer shell portion and an inner inflatable bladder. The pressure in the bladder is monitored regularly by a pressure sensor, during a breastfeeding session. When the pressure drops below a preselected pressure, a controller directs a pump to pump air into the inflatable bladder to maintain the preselected pressure. The volume of added air is monitored during the breastfeeding session. Various calibrations are used to correlate the amount of added air, to the volume of breast milk withdrawn from the breast. The volume of breast milk withdrawn during breastfeeding is calculated and displayed throughout the breastfeeding session.

A device for measuring a mechanical property of a tissue includes a probe configured to perturb the tissue with movement relative to a surface of the tissue, an actuator coupled to the probe to move the probe, a detector configured to measure a response of the tissue to the perturbation, and a controller coupled to the actuator and the detector. The controller drives the actuator using a stochastic sequence and determines the mechanical property of the tissue using the measured response received from the detector. The probe can be coupled to the tissue surface. The device can include a reference surface configured to contact the tissue surface. The probe may include a set of interchangeable heads, the set including a head for lateral movement of the probe and a head for perpendicular movement of the probe. The perturbation can include extension of the tissue with the probe or sliding the probe across the tissue surface and may also include indentation of the tissue with the probe. In some embodiments, the actuator includes a Lorentz force linear actuator. The mechanical property may be determined using non-linear stochastic system identification. The mechanical property may be indicative of, for example, tissue compliance and tissue elasticity. The device can further include a handle for manual application of the probe to the surface of the tissue and may include an accelerometer detecting an orientation of the probe. The device can be used to test skin tissue of an animal, plant tissue, such as fruit and vegetables, or any other biological tissue.

The present invention generally relates to blood pressure monitoring. In some embodiments, methods and devices of measuring a mean arterial pressure are provided and/or monitoring blood pressure changes. A wrist-worn device may include a plurality of sensors backed by a plurality of actuators. Subsets of the plurality of sensors may be selectively actuateable against a wrist of a user using one or more of the plurality of actuators. A preferred sensor and location may be identified based on pressure signals received from each of the sensors. In some embodiments, devices may use a fluid bladder coupled with piezoelectric film sensors. A fluid bladder pressure sensor may be used to calibrate the piezoelectric film signal to provide a static and dynamic pressure reading. In yet another embodiment, a mean arterial pressure may be calculated by processing a swept pressure signal obtained as a sensor is swept through different heights.

The present invention provides elastic constant and visco elastic constant measurement apparatus etc. for measuring in the ROI in living tissues elastic constants such as shear modulus, Poisson's ratio, Lame constants, etc., visco elastic constants such as visco shear modulus, visco Poisson's ratio, visco Lame constants, etc. and density even if there exist another mechanical sources and uncontrollable mechanical sources in the object. The elastic constant and visco elastic constant measurement apparatus is equipped with means of data storing 2 (storage of deformation data measured in the ROI 7 etc.) and means of calculating elastic and visco elastic constants 1 (calculator of shear modulus etc. at arbitrary point in the ROI from measured strain tensor data etc.), the means of calculating elastic and visco elastic constants numerically determines elastic constants etc. from the first order partial differential equations relating elastic constants etc. and strain tensor etc.

An automatic skin perfusion measuring device automatically analyzes perfusion measurements to identify motion artifact and SPP values. Motion artifact is ignored. Perfusion measurements are designated as SPP values if various criteria are met. SPP value criteria pertain to factors including cuff pressure, perfusion, perfusion change percentages relative to previous and subsequent perfusion measurements, and whether perfusion measurements are increasing or decreasing relative to previous and subsequent perfusion measurements.

Methods and systems are provided for determining a condition of an organ, or epithelial or stromal tissue, for example in the human breast. The methods incorporate sonophoresis, the application of ultrasonic energy, in order to condition tissue for testing and enhance test measurements. A plurality of electrodes are used to measure surface and transepithelial electropotential and impedance of breast tissue at one or more locations and at several frequencies, particularly very low frequencies. An agent may be introduced into the region of tissue to enhance electrophysiological characteristics. Pressure, drugs and other agents can optionally be applied for enhanced diagnosis. Tissue condition is determined based on the electropotential and impedance profile at different depths of the epithelium, stroma, tissue, or organ, together with an estimate of the functional changes in the epithelium due to altered ion transport and electrophysiological properties of the tissue. Devices for practicing the disclosed methods are also provided.

A method for testing the effect of a skin care product includes measuring a mechanical property of skin tissue using nonlinear stochastic system identification, applying the product to the skin, repeating the measurement of the mechanical property after the application of the product, and comparing the before and after measurements to quantify the effect of the product.

Measuring the mechanical property of the skin can include placing a probe against a surface of the skin, perturbing the skin with the probe using a stochastic sequence, and measuring the response of the skin to the perturbation. Perturbing the skin can include indenting the skin with the probe, extending the skin with the probe, and sliding the probe across the skin surface. The mechanical property may be indicative of skin compliance, skin elasticity, skin stiffness, or skin damping. The mechanical property can be dependent on perturbation depth and may be measured at a plurality of anatomical locations.

A body monitoring system can include a wearable device, and a circuit for conducting electrical signals having an electrically conductive yarn knitted into the device. The circuit can further include a sensor circuit configured to sense a variable in an area of a body to which the device is applied. The circuit can further include a transmission circuit configured to transmit an electrical signal representing a value of a variable in an area of a body to another location. The other location can be an external device separate from the wearable device, such as an electronic display unit.

A method for evaluating pain experienced by a human is disclosed. The method includes applying a first noxious stimulus to a normative site on the human, wherein the first noxious stimulus is applied below a pain threshold of the human and logging a first information associated with the first noxious stimulus. The method further includes applying a second noxious stimulus to a source of the pain in the human, wherein the second noxious stimulus is applied until pain threshold is reached and logging a second information associated with the second noxious stimulus. The method further includes increasing the second noxious stimulus until pain tolerance is reached and logging a third information associated with the second noxious stimulus. The method further includes continuing to apply the second noxious stimulus until the human can no longer tolerate the second noxious stimulus and logging a fourth information associated with the second noxious stimulus.

A computational efficient algorithm for compression analysis of free-hand static elasticity imaging performed using medical diagnostic ultrasound imaging equipment offers tissue compression quality and quantity feedback to the operator. The algorithm includes a criterion for automatic selection of the most advantageous pre- and post-compression frame pairs delivering elasticity images of optimal dynamic ranges (DR) and signal-to-noise ratios (SNR). The use of the algorithm in real time eases operator training and reduces significantly the amount of artifact in the elasticity images while lowering the computational burden.

Based on the ultrasonic tomographic data measured by exerting the pressure to the tissue of a body of the subject 1, the elastic data such as the distortion or the elastic modulus of the tissue at the plural measurement points in the tomographic site of the subject body are obtained. Based on the obtained elastic data, the elastic image in the tomographic site is generated to be displayed. The distribution of the elastic data such as the distortion and the elastic modulus in the interest region ROI set on the elastic image is displayed as the histogram. The new quantitative information which reflects the tissue property is supplied in addition to the information which relates to the elasticity of the tissue graded with the hue or brightness for assisting in the tissue identification.

Methods and apparatus based on vibromyography technology are provided that overcome the substantial limitations of current VMG muscle assessment approaches. Specifically, embodiments of the invention provide a means by which clinicians and trainers can perform real-time muscle assessment during typical functional activities (activities involving substantial human movements). In some embodiments, the invention allows the artisan to simultaneously measure muscle forces being generated by complementary, supplementary, and/or antagonistic muscle pairs such that real-time muscle effort ratios can be calculated. In some embodiments, the measurements provide a means by which clinicians and trainers can diagnose musculo-skeletal injuries and pains associated with muscle imbalances.

Methods and instruments for characterizing a material, such as the properties of bone in a living human subject, using a test probe constructed for insertion into the material and a reference probe aligned with the test probe in a housing. The housing is hand held or placed so that the reference probe contacts the surface of the material under pressure applied either by hand or by the weight of the housing. The test probe is inserted into the material to indent the material while maintaining the reference probe substantially under the hand pressure or weight of the housing allowing evaluation of a property of the material related to indentation of the material by the probe. Force can be generated by a voice coil in a magnet structure to the end of which the test probe is connected and supported in the magnet structure by a flexure, opposing flexures, a linear translation stage, or a linear bearing. Optionally, a measurement unit containing the test probe and reference probe is connected to a base unit with a wireless connection, allowing in the field material testing.