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891 results about "Light irradiation" patented technology

Light irradiation of molecules is the most popular method for the formation of active species. Light absorption can result in either the excitation of particles or photodissociation of molecules to form atoms and radicals. Both continuous and pulse light sources are used.

High-reliability PbS quantum dot film, preparation method thereof and photoelectric device

The invention discloses a high-reliability PbS quantum dot film, a preparation method thereof and a photoelectric device. The preparation method comprises the following steps: 1) obtaining a first quantum dot solution; 2) adding medium-chain and long-chain amine; 3) adding an anti-solvent; 4) obtaining medium-chain and long-chain amine modified PbS quantum dot solids; 5) obtaining a second quantum dot solution; (6) forming a PbS quantum dot coating; 7) forming a mercaptan solution; 8) coating the PbS quantum dot coating with a mercaptan solution; (9) annealing treatment; 10) forming a new PbS quantum dot coating, and coating the new PbS quantum dot coating with a mercaptan solution; according to the PbS quantum dot thin film and the preparation method thereof, through the induction and synergistic effect of halogen atoms, the binding capacity of halogenated mercaptan ligands and the surface of the PbS quantum dot thin film is enhanced, the surface defect state of the PbS quantum dots is effectively inhibited, and the reliability of the PbS quantum dot thin film and a photoelectric device under the conditions of high temperature, high humidity and long-time illumination is remarkably improved.
Owner:WENZHOU YINGRUI INFRARED TECH CO LTD

Long-persistent luminescence emitter and long-persistent luminescent device

A long-persistent luminescence emitter containing a polymer that contains, relative to the total molar amount of an electron donor structural unit and an electron acceptor structural unit therein, 70 mol % or more of an electron donor structural unit and less than 30 mol % of an electron acceptor structural unit, or containing a polymer that contains, relative to the total molar amount of an electron donor structural unit and an electron acceptor structural unit therein. 70 mol % or more of an electron acceptor structural unit and less than 30 mol % of an electron donor structural unit. The emission decay after stopping light irradiation to the emitter is power law decay.
Owner:OKINAWA INST OF SCI & TECH SCHOOL

Silver vanadate photocatalytic material, preparation method thereof and illuminating lamp

The invention discloses a silver vanadate photocatalytic material, a preparation method thereof and an illuminating lamp. The preparation method comprises the following steps: firstly, respectively dissolving NH4VO3 and AgNO3 in deionized water, uniformly mixing by magnetic stirring, adjusting the pH value of the solution, and then carrying out hydrothermal synthesis reaction to obtain the Ag3VO4 photocatalytic material. The Ag3VO4 photocatalytic material with controllable morphology, uniform particle size and good dispersity is prepared by adopting a synthesis strategy of a one-step hydrothermal method, the performance of the photocatalyst is optimized by regulating and controlling the pH value, the raw materials and the process are simple, the conditions are easy to control, the cost is low, the photocatalytic degradation rate of the catalyst to organic pollutants is high, and the method is suitable for industrial production. The stability of a crystal structure and catalytic activity can be kept under long-term illumination, and the functional application of a photocatalytic air purification technology can be realized by integrating with an illumination lamp.
Owner:FOSHAN LIGHTING CHANCHANG PHOTOELECTRIC CO LTD

Collagen-based injectable fiber hydrogel as well as preparation method and application thereof

The invention belongs to the technical field of biomedical materials and regenerative medicine, and relates to collagen-based injectable fiber hydrogel as well as a preparation method and application thereof. According to the injectable fiber hydrogel, methacrylated collagen and dithiothreitol are subjected to a thiol-ene click reaction rapidly under the action of a photoinitiator through illumination, a primary cross-linked network is formed, and the injection and in-situ gel forming requirements are met; then under the conditions that the pH is 6.5-8.0 and the temperature is 30-39 DEG C, collagen molecules are self-assembled into a nanofiber structure, and a bionic network similar to a natural extracellular matrix is obtained. The hydrogel disclosed by the invention has the advantages of rapid gelation, structural biomimetic property and biological activity; residual sulfydryl endows the hydrogel with active oxygen scavenging capacity, so that oxidative stress can be relieved, and immune response can be regulated; the fibrotic structure promotes cell adhesion, migration and tissue regeneration.
Owner:EAST CHINA UNIV OF SCI & TECH

Method for preparing high-value chemicals by photocatalysis-driven beta-O-4 lignin depolymerization and coupling cascade reaction

The invention discloses a method for preparing high-value chemicals through photocatalytic driving of beta-O-4 lignin depolymerization and coupling cascade reaction, and belongs to the technical field of photocatalytic biomass resource conversion. The method comprises the following steps: (1) dispersing a beta-O-4 lignin raw material into a solvent containing a photocatalyst; (2) introducing a normal-temperature chemically stable gas to replace air in a reaction system; and (3) carrying out a depolymerization reaction of beta-O-4 bonds and an in-situ C-C bond coupling reaction under an illumination condition to generate a target product. And (4) separating and purifying the product and recovering the catalyst. Through photocatalytic cascade reaction design, the defects of harsh reaction conditions and multi-step separation in a traditional method are avoided, the method has the advantages of mild reaction conditions, high atom utilization rate, high product selectivity and environmental friendliness, and a new way is provided for high-value utilization of lignin.
Owner:ZHEJIANG UNIV OF TECH

Coating apparatus, dryer, light irradiation device and coating system

A coating apparatus 10 for applying a film-forming liquid to a peripheral edge of a board while moving a board and a coating unit 20 relative to each other, wherein the coating unit 20 includes a coating mechanism 21 and an extension mechanism 30, and wherein the coating mechanism 21 has a coating part 22 for applying the film-forming liquid to at least a peripheral edge face of the board, and wherein the extension mechanism 30 has a coating part 22 for applying the film-forming liquid to at least a peripheral edge face of the board. The extension mechanism 30 has an extension part 31 that extends the film-forming liquid applied by the application part 22 to the peripheral edge face and the peripheral upper and lower faces of the board in the form of a thin film, and a force mechanism 34 that forces the extension part 31 toward the peripheral edge face and the peripheral upper and lower faces of the board, and the extension part 31 is configured to be removable without removing the force mechanism 34 from the extension mechanism 30.
Owner:ENATECH CORP

Microneedle array paper-based chip as well as preparation method and application thereof

The invention discloses a self-driven diagnosis and treatment integrated microneedle array paper-based chip as well as a preparation method and application thereof, and belongs to the technical field of biomedicine. The microneedle array chip system comprises a function integration module which at least comprises a self-powered extraction unit, a sensing detection unit and a controlled drug delivery unit. According to the microneedle array paper-based chip, biomarkers in skin interstitial fluid are efficiently collected based on a self-powered thermoelectric chemical battery microneedle, PtPB (at) PEG (at) HA nanoparticles loaded on an immunochromatography test strip combination pad are triggered to be subjected to ring opening, a hybridization chain reaction is induced to generate DNA nano-enzyme, and TMB is catalyzed to develop color; the open-loop nanoparticles can be used for SERS cross detection of biomarkers, and can be used as a thermal initiator to activate the phase change microneedle under the irradiation of near-infrared light, so that drugs are released as required, and precise treatment is realized. Besides, objective quantitative analysis of color signals is realized by constructing a convolutional neural network model, and the system has the functions of naked eye screening, intelligent quantification and personalized treatment, and can improve the home management ability of early skin cancer.
Owner:CHINA PHARM UNIV

Multi-ring mask, light irradiation device, optical microscope, and photoacoustic microscope

ActiveUS12554119B2MicroscopesNon-linear opticsPhotoacoustic microscopyLight irradiation
A light irradiation apparatus focuses light on a surface or an inside of an object to observe or process the object, and includes a laser light source, a lens, a lens, a mask, a wave plate, and a lens. The mask is a multi-ring mask for spatially intensity-modulating input light in a beam cross-section and outputting modulated light, and includes a plurality of ring-shaped light-shielding areas provided around a center position, and a transmitting area provided between two adjacent light-shielding areas out of the plurality of light-shielding areas. A radial width of each of the two adjacent light-shielding areas out of the plurality of light-shielding areas is larger than a radial width of the transmitting area provided between the two light-shielding areas.
Owner:HAMAMATSU PHOTONICS KK

A composite degradation preparation for degrading microplastics in wastewater and a method of application thereof

The application discloses a composite degradation preparation for degrading microplastics in wastewater and an application method thereof, and relates to the technical field of wastewater purification. The preparation is prepared by three steps of preparing a rare earth doped titanium-based porous framework, preparing an enzyme-containing bacteria coated precursor solution, and in-situ cross-linking and co-fixing. The framework realizes visible light response and magnetic separation characteristics. The co-fixing of enzyme and bacteria is completed by microcapsule embedding and carrier adsorption cross-linking. The preparation integrates the functions of photocatalysis, enzymatic degradation and microbial degradation. In application, the wastewater is pretreated to SS≤60mg / L, and then the preparation is added to a degradation tank. Under the conditions of 395-450nm light, 25-40 DEG C, and pH 6.0-8.0, the wastewater is degraded by stage light irradiation. Finally, the preparation is recycled by magnetic separation. The preparation solves the problem of free radical damage in the light-biological synergy, and has strong impact resistance, high microplastic removal rate, and recyclable preparation. The preparation is suitable for continuous treatment of wastewater, greatly reduces the operation cost, and is suitable for purification treatment of various wastewater containing microplastics.
Owner:HUIZHOU UNIV

Natural light irradiation curing device for trenchless pipeline repair

ActiveCN224065079Ueasy to collectConvenient for natural light curing and repair workPigs/molesLight irradiationLight pipe
The utility model belongs to the technical field of pipeline repair, and particularly relates to a natural light irradiation curing device for trenchless pipeline repair, which comprises a light guide pipe, a light condensing pipe fixedly mounted at one end of the light guide pipe, a first light beam connector fixedly mounted at one end of the light condensing pipe, and an optical cable winch arranged on one side of the first light beam connector. A motor is fixedly installed on one side of the optical cable winch, a winding roller is arranged on the inner side of the optical cable winch, an optical cable is arranged on the winding roller, a tractor is arranged on one side of the optical cable winch, a second light beam connector is fixedly installed on the top of the tractor, and a second convex lens is arranged at one end of the second light beam connector. The fixed rod, the movable rod, the movable groove, the compression spring, the inner rod, the supporting base and the supporting pulley are arranged and used in cooperation, the supporting base and the supporting pulley can support the top of a pipeline by adjusting the movable inner rod in a lifting mode, the stability of a tractor in the moving process is conveniently improved, and the interior of the pipeline can be better repaired conveniently.
Owner:HENAN JINYIDA ENVIRONMENTAL TECH CO LTD

Extreme ultraviolet coherent diffraction tomographic imaging method based on random phase modulation

The application discloses an extreme ultraviolet coherent diffraction stack imaging method based on random phase modulation, which is realized through an extreme ultraviolet phase modulation stack imaging light path of a random phase plate. The imaging light path comprises a high harmonic light source, a pinhole, a phase plate and a photoelectric coupling detector. The high harmonic light source emits light to irradiate a probe. A sample to be measured is arranged between the pinhole and the phase plate. The phase plate is used for phase modulation. The light irradiated by the probe is irradiated onto the sample to be measured through the pinhole, propagates a preset distance, and then reaches the plane of the photoelectric coupling detector through the phase plate. The diffraction pattern of the sample to be measured is obtained. Iterative processing is performed on the first amplitude information of the emergent light, the second amplitude information of the reverse propagation, the first diffraction pattern light field and the first diffraction pattern light spot. The best sample to be measured pattern is obtained, and the best sample to be measured information and the best light irradiation probe information are separated. The method can realize lensless imaging, avoids aberration and aperture limitation caused by the use of a lens, and has a simpler system and lower cost.
Owner:ZJU HANGZHOU GLOBAL SCI & TECH INNOVATION CENT

Method for analyzing bio-substance

A bio-substance analysis method using a sensing substrate having a fluid channel is disclosed. The method includes mixing retroreflective particles with a detection solution containing a target bio-substance, wherein a first bio-recognition substance selectively reacting with the target bio-substance is modified on the retroreflective particles; placing the sensing substrate so that a bottom is located under a cover in a direction of gravity; injecting the detection solution containing therein the retroreflective particles into a fluid channel and maintaining the solution in the channel for a first time duration; turning the sensing substrate upside down so that the bottom is located above the cover in the direction of gravity and maintaining the sensing substrate in the turned state for a second time duration; irradiating light into the fluid channel through the bottom; and generating and analyzing an image based on light retroreflected from the retroreflective particles.
Owner:AJOU UNIV IND ACADEMIC COOP FOUND

Method for functionalizing biopolymers and crosslinking thereof

The present invention relates to a method for functionalizing a biopolymer having an -OH group or an -NH2 group by reacting the biopolymer with at least one compound having at least one C=C bond or C≡C bond and containing a chromophore that absorbs UV-Vis radiation directly adjacent to this bond. The present invention also relates to a method for obtaining a solid biopolymer material by reversibly crosslinking the functionalized biopolymer obtained by the above method under UV-Vis light irradiation. Furthermore, the present invention relates to the use of functionalized biopolymers as support materials for 3D bioprinting, or as materials for manufacturing structures selected from spheroids, organoids, artificial organs, coatings, and tissue models.
Owner:POLBIONICA SPOLKA AKCYJNA

Method and system for identifying internal defects in a reactor pressure vessel, computer equipment and computer-readable storage medium

This application discloses a method and system for identifying internal defects in a reactor pressure vessel, a computer device, and a computer-readable storage medium. The method includes the steps of: collecting image data of the pressure vessel surface; constructing a light irradiation angle attention mechanism to create a feature map using the images in the dataset and generating a spatial attention map based on the spatial relationships of the feature maps; and improving a YOLOv5 model using the light irradiation angle attention mechanism and identifying surface defects in the pressure vessel using the improved YOLOv5. It features high defect identification efficiency and a low detection miss rate. It effectively addresses common problems when performing defect detection under various light irradiation conditions. This ability to accurately identify and distinguish defects is crucial for ensuring the safe operation of the pressure vessel, especially during routine maintenance and inspections.

Methods for producing three-dimensional objects

A method of forming a three-dimensional object is carried out by: (a) providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; (b) filling the build region with a polymerizable liquid, the polymerizable liquid comprising a mixture of: (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from the first component; (c) irradiating the build region with light through the optically transparent member to form a solid blocked polymer scaffold and advancing the carrier away from the build surface to form a three-dimensional intermediate having the same shape as, or a shape to be imparted to, the three-dimensional object, with the intermediate containing the second solidifiable component; and then (d) solidifying and / or curing the second solidifiable component to form from said three-dimensional intermediate the three-dimensional object.
Owner:CARBON INC

Photo-crosslinking rapidly-curable battery binder and preparation method thereof

The invention provides a photo-crosslinking type battery binder capable of being rapidly cured and a preparation method of the photo-crosslinking type battery binder. The method comprises the following steps: (1) dissolving hydroxyl-terminated hydrogenated butyronitrile in an organic solvent to obtain a solution A; (2) adding diisocyanate and a catalyst into the solution A for reaction to obtain a solution B; (3) adding polyol into the solution B for reaction to obtain a solution C; and (4) adding an acrylic acid compound into the solution C for reaction to obtain a product precursor D, and illuminating the product precursor D for 4-6 minutes to obtain the photo-crosslinking type battery binder capable of being quickly cured. According to the invention, a stable cross-linking system which can be rapidly cured under the illumination condition is constructed, excellent bonding strength and good polarity are retained, and meanwhile, the adhesive also has good mechanical properties.
Owner:BEIJING UNIV OF CHEM TECH

Tetrahydronaphthalene-1-ketone as well as preparation method and application thereof

PendingCN121930085AOrganic compound preparationOrganic free radical generationLight irradiationOrganic synthesis
The invention belongs to the field of organic synthesis, and discloses tetrahydronaphthalene-1-ketone as well as a preparation method and application thereof.The tetrahydronaphthalene-1-ketone is obtained by mixing tetrahydronaphthalene, carbon nitride and persulfate in an organic solvent (acetonitrile or dichloromethane) and reacting under the illumination condition of 395-457 nm. The preparation method disclosed by the invention is relatively high in yield, conforms to a green production concept, is environment-friendly, low in cost, simple to operate and high in selectivity, and is expected to be used for industrial production.
Owner:FUZHOU SANHE PHARMACHEM +1

Radiation resistant underwater fill light

The utility model discloses a kind of irradiation resistance underwater light supplementing lamps, belong to underwater light supplementing lamp technical field, solve the irradiation range of the underwater light supplementing lamp of multiple lamp body becomes larger, but condensing effect is obviously worse, so cannot condensing clear irradiation certain object, affect the visibility when actual underwater operation problem. Including circular arc lamp panel, the lamp body of several fixed connections in lamp panel, and the light-reflecting plate of the rotation connection in lamp panel outer circle, several light-reflecting plate can be relative lamp panel flip, several light-reflecting plate synchronous rotation setting. The utility model uses, when needing large range illumination, traction electromagnet pulls connection rope, makes light-reflecting plate deflect, torsional spring accumulates elastic potential energy, turns wire pole and prevents connection rope scratch breakage. When needing condensing irradiation, traction electromagnet is powered off, release connection rope, torsional spring releases potential energy and drives light-reflecting plate reverse deflection, forms spotlight cover, makes light concentration, clear irradiation object, does not affect underwater operation visibility.
Owner:SHAOXING NUCLEAR VISION TECHNOLOGY CO LTD

A method for synthesizing nitrogen-containing heteroarene carboxylic acid compounds based on nitrogen-containing heteroarene carbon-hydrogen bond carboxylation reaction

The application discloses a method for synthesizing nitrogen-containing heteroarene carboxylic acid compounds based on nitrogen-containing heteroarene carbon-hydrogen bond carboxylation reaction and belongs to the technical field of organic synthesis, and specifically comprises the following steps: adding a reaction substrate, an organic catalyst, a base and an additive into a reaction container, then adding a solvent under a CO2 atmosphere, and stirring and reacting at room temperature or under heating in a light irradiation condition; and performing post-treatment on a reaction product, separating and purifying the reaction product, and obtaining nitrogen-containing heteroarene carboxylic acid compounds and derivatives thereof. The scheme has the characteristics of mild reaction condition, wide reaction substrate range, good yield and good regioselectivity, and cheap and easily-obtained raw materials, can efficiently realize nitrogen-containing heteroarene carbon-hydrogen bond carboxylation reaction, synthesize important nitrogen-containing heteroarene carboxylic acid compounds, and has a good application prospect.
Owner:SICHUAN UNIV

Intraoral light irradiation device

PendingCN121568663AOthrodonticsLight therapyLight irradiationAlveolar mucosa
The invention provides an intraoral light irradiation device which has good wearing comfort and can accurately irradiate light to the gingiva and alveolar mucosa of an orthodontic tooth. An intraoral light irradiation device (1) is provided with: a mouthpiece (2) formed in a U-shape; and a light source (4) which is disposed on the brace (2) and which is provided with a plurality of light emitters (3) that irradiate light to the gums of the wearer. Wherein the mouthpiece (2) comprises a bite tray (5) formed in a U-shape, a front flange (6) facing the outer face of the gum of the wearer, and a rear flange (7) facing the inner face of the gum of the wearer; wherein the front flange (6) and the rear flange (7) are translucent, and the light source (4) is configured to be capable of irradiating light from the inner peripheral surface of the front flange (6) and the outer peripheral surface of the rear flange (7); a protruding part (11) is formed at the end of the front flange (6) and extends out from the meshing tray (5) in the extending direction of the front flange (6).
Owner:JAPAN PBM HEALING KK

Method for evaluating semiconductor substrate

Method for evaluating electrical properties of a semiconductor substrate (1), wherein the method comprises the following steps: Formation of a pn junction on a surface of the semiconductor substrate (1); Attaching the semiconductor substrate (1) to a wafer holder (8) which is equipped with a device (6) for performing light irradiation (4) on the surface of the semiconductor substrate (1) and a device (7) for measuring the amount of light for the irradiation; Applying light irradiation (4) to the surface of the semiconductor substrate (1) for a predetermined time; and Measuring a quantity of carriers generated after irradiation (4) of the pn junction, at least after switching off the irradiation (4), wherein a quantity of carriers generated during the light irradiation (4) of the pn junction is measured in the step of performing the light irradiation (4), the quantity of carriers produced during light irradiation (4) and the quantity of carriers produced after light irradiation (4) are measured with a carrier measuring probe (5) which is provided separately from the equipment (6) for carrying out the light irradiation (4) and the equipment (7) for measuring the quantity of light for the irradiation, and the carrier measuring probe (5) is a non-contact Kelvin probe or a mercury probe.
Owner:SHIN ETSU HANDOTAI CO LTD

Clamping assembly, testing machine and executing mechanism

The invention provides a clamping assembly, a test machine and an execution mechanism, and the clamping assembly comprises a substrate which comprises a chip placement area for bearing a chip; the chip placing area comprises a light-transmitting area corresponding to the light-sensitive area of the chip; the pressing plate is arranged on one side of the substrate and is configured to be matched with the substrate to position the chip; the pressing plate comprises a first pin assembly and a second pin assembly; the first pin assembly is configured to be conductively connected with a pin of the chip; the second pin assembly comprises a switching pin; the substrate further comprises an avoiding area used for avoiding the second pin assembly. Through the cooperation of the substrate and the pressing plate, the chip can be placed in an inverted mode, bottom lighting irradiation can be achieved, transformation of a testing machine and an executing mechanism can be reduced, and high universality is achieved.
Owner:SHANGHAI HESAI INTELLIGENT TECHNOLOGY CO LTD

Preparation of N-alkoxyamine HALS from corresponding hydroxylamines

A process for the preparation of a compound of the sterically hindered alkoxyamine class is described, the process comprises the step of alkylating a sterically hindered hydroxylamine compound to a corresponding sterically hindered alkoxyamine by reacting said sterically hindered nitroxyl compound with a compound capable of producing a carbon-central alkyl radical, typically a territorial or secondary alkyl radical, the compounds capable of generating carbon-center alkyl radicals are selected from thermal radical initiators that form radical species in the temperature range of 40 DEG C to 200 DEG C, and from photoinitiators that undergo light excitation when irradiated with UV light or visible light in the range of 180 to 700 nm, in particular UV light in the range of 180 to 380 nm, the compounds capable of generating carbon center alkyl radicals are typically selected from the class of organic peroxides, azo compounds, benzoyl derivatives, benzophenone derivatives, thioxanthone derivatives, benzoin derivatives, benzoyl phosphine oxide derivatives, and the like. The invention relates to a peroxide, for example, selected from the group consisting of diacyl peroxides of formula (A), peracid esters of this formula (A), and oxalic acid peracid esters of formula (D) R-CO-O-O-Z-R (A), r-Z ''-X-CO-CO-O-O-Z''-R (D) wherein each R independently represents a primary or secondary alkyl or cycloalkyl group, preferably comprising from 1 to 15 carbon atoms, and X is oxygen-O-or peroxy-O-O-, Z represents CO or an alkylene group bonded to a quaternary carbon atom, the quaternary carbon atom being an alkylene group of formula (C) R '-C-R' (C), wherein each R'is selected from alkyl groups having 1 to 15 carbon atoms, and Z "represents the alkylene group bonded to a quaternary carbon atom having the formula (C). The described process produces the corresponding O-alkylated derivatives of the sterically hindered hydroxylamines, typically compounds of the class referred to as N-O-alkyl HALS, with very high selectivity and conversion and without the need for the use of catalysts, in particular metal catalysts.
Owner:GENE CHEMISTRY CO LTD

Polycyclic aromatic hydrocarbon cationic compound with high photothermal conversion efficiency as well as synthesis method and application of polycyclic aromatic hydrocarbon cationic compound

The invention discloses a polycyclic aromatic hydrocarbon cationic compound with high photothermal conversion efficiency and a synthesis method and application thereof, and belongs to the technical field of organic functional materials. According to the method, conjugation expansion is realized through a Scholl reaction, and a large-steric-hindrance group is introduced for dynamic protection, so that a compound A is successfully obtained. The powder of the compound A shows excellent photo-thermal conversion performance under 1064 nm near-infrared light irradiation, shows up to 90% of photo-thermal conversion efficiency under 1.4 W cm <-> power density, can be rapidly heated to 330 DEG C or above, and shows excellent photo-thermal stability due to the fact that the performance is not attenuated after multiple times of switching cycle. As a photo-thermal agent, the compound can be used for low-power non-contact precision welding of various metal materials, and has important application value in the fields of microelectronic manufacturing, precision instrument assembly and the like. According to the invention, the technical problem that the existing photo-thermal material is difficult to realize high photo-thermal conversion efficiency and high limit working temperature at the same time in a 1064nm window is successfully solved.
Owner:TIANJIN UNIV

A fusion film-wrapped composite nanodelivery system, and a preparation method and application thereof

PendingCN122297701AFusobacteriaDrug release
This invention discloses a composite nanodelivery system encapsulated in a fusion membrane, its preparation method, and its applications. The nanodelivery system comprises a Ti3C2 / TiO2 / CuInS2 composite material, oxaliplatin loaded thereon, and a fusion membrane encapsulating the outer layer; the fusion membrane is formed by the fusion of Fusobacterium nucleatum extravesicles and M1 macrophage membranes. This invention also discloses a method for preparing the nanodelivery system, including the steps of preparing the Ti3C2 / TiO2 / CuInS2 composite material, preparing the fusion membrane, loading oxaliplatin, and encapsulating it in the fusion membrane. The nanodelivery system prepared by this invention exhibits pH-responsive drug release characteristics, generating H2S in the tumor microenvironment and H2 under light irradiation, while also possessing photocatalytic activity. This invention combines chemotherapy, photoelectrocatalytic therapy, and the regulation of multiple active substances, and can be used to prepare drugs for treating malignant tumors of the digestive system.
Owner:NINGBO MEDICAL CENT LIHUILI HOSPITACL

Process for the preparation of phosphate crosslinked organic porous uranium extractants

The application belongs to the technical field of polymer materials and engineering, and discloses a preparation method of a phosphate cross-linked organic porous uranium extractant. A phenylacetylene is cross-linked with 1,4-dithioerythritol through a click chemistry reaction by using a photo-induced cross-linking method. Compared with common mercaptans, 1,4-dithioerythritol contains an adsorption group. The cross-linking reaction is carried out under the condition that the ratio is 1:3 and the light irradiation time is 1h. An organic polymer PCM with a porous structure is synthesized. After the synthesized polymer is subjected to Soxhlet extraction for 48h, the polymer is modified by phosphating with phosphorus oxychloride to prepare a porous polymer containing a phosphate group. After the synthesized polymer is subjected to Soxhlet extraction for 48h and is dried, a purple black powder P-PCM is obtained. The target polymer can be synthesized only through three steps of reactions. The polymer preparation is relatively simple under the photo-induced cross-linking, which is of great significance to improving the uranium adsorption capacity. The preparation is simple, the reaction is stable, the safety is high, and the cost is low through the click chemistry reaction.
Owner:QIQIHAR UNIVERSITY

A method for migrating C(sp²)-H / C(sp³)-H cross-coupling catalyzed by metal / photoredox catalysis

This invention discloses a migration C(sp²)-H / C(sp³)-H cross-coupling reaction achieved using metal / photoredox catalysis, belonging to the fields of organic chemistry and medicinal chemistry. Under the action of a nickel source, photocatalyst, ligands, base, and additives, this invention enables the reaction of alkanes with ortho-alkenyl-substituted aryl halides or ortho-pyridine-substituted aryl halides in an organic solvent under light irradiation, yielding a series of polysubstituted olefins or polysubstituted aromatic compounds with excellent regioselectivity, stereoselectivity, and good yields, which can serve as active pharmaceutical molecules. This invention uses inexpensive transition metal nickel as a catalyst, readily available alkanes and haloaromatics as raw materials, and features mild and simple conditions, good functional group compatibility, and easy operation.
Owner:SHANGHAI FULE PHARM TECH CO LTD

A method of iodine-induced lithium intercalation exfoliation of two-dimensional materials

This invention relates to a method for iodine-induced lithium intercalation and exfoliation of two-dimensional materials, comprising the following steps: uniformly mixing a target bulk layered material with an inorganic salt to obtain mixture A; the inorganic salt contains lithium iodide; heating mixture A to 280–400°C under a vacuum environment or protective atmosphere, while simultaneously applying ultraviolet light irradiation, and obtaining mixture B through solid-state lithiation treatment; dispersing mixture B in deionized water, and obtaining the two-dimensional material through hydrolysis exfoliation, separation, washing, and drying. This invention uses an inorganic salt containing lithium iodide as the intercalation medium, and through the synergistic excitation of a light field and a thermal field, induces the oxidative decomposition of halide ions and the release of electrons, driving alkali metal ions to intercalate into the interlayer gaps of the bulk layered material to achieve in-situ solid-state intercalation. Then, through hydrolysis exfoliation, an ultrathin two-dimensional material with a large lateral dimension is obtained. The process is safe, has high intercalation efficiency, and good versatility.
Owner:HUAZHONG UNIV OF SCI & TECH

Corneal contact lens with self-healing function and preparation method thereof

The invention discloses a corneal contact lens with a self-healing function and a preparation method of the corneal contact lens, and belongs to the technical field of macromolecules. The preparation method comprises the following steps: dissolving a zwitterionic compound into water or a buffer solution, immersing a corneal contact lens into the solution, adding a cross-linking agent and an initiator, uniformly mixing, standing to enable molecules of the zwitterionic compound, the cross-linking agent and the initiator to be fully distributed in a spatial network of the orthokeratology lens, and polymerizing under ultraviolet irradiation to obtain the orthokeratology lens. After unreacted monomers are removed, the corneal contact lens with the self-healing function is obtained; the zwitterionic compound is one or a combination of more than two of N-(2-amino-2-oxoethyl) acrylamide, acrylamide carboxyl betaine and acrylic ester carboxyl betaine. The corneal contact lens prepared by the invention can realize self-repairing of scratches, solves the problems of bacterial hiding, corneal friction injury, frequent replacement and the like caused by surface injury of a traditional corneal contact lens, and greatly reduces the economic burden while ensuring the eye health of a wearer.
Owner:DALIAN UNIV OF TECH