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25results about How to "Effective sterilization" patented technology

Preparation method of antibacterial modified high-performance nylon fiber

PendingCN122257140Aavoid uneven loadimprove performance
The present application belongs to the technical field of high-performance nylon fiber materials, and particularly relates to a preparation method of antibacterial modified high-performance nylon fiber. The preparation method comprises the following steps: S1, a triazine ring-containing dicarboxylic acid is prepared by taking cyanuric chloride, 4-amino-2,2,6,6-tetramethylpiperidine and p-hydroxybenzoic acid as raw materials, triphenylphosphine oxide is subjected to nitration treatment and reduction treatment to obtain tris(3-aminophenyl)phosphine oxide, and the triazine ring-containing dicarboxylic acid and the tris(3-aminophenyl)phosphine oxide are mixed for a synthesis reaction to obtain modified hyperbranched polyamide; S2, polyamide masterbatch, modified hyperbranched polyamide, antibacterial material, zinc stearate and antioxidant are melt blended, extruded and granulated to obtain modified nylon chip; and S3, the modified nylon chip is subjected to melt spinning to obtain antibacterial modified high-performance nylon fiber. The present application not only ensures that the fiber has good antibacterial performance, but also effectively improves the breaking strength and flame retardant performance.
Owner:SUZHOU HANCHANG HOME TEXTILE CO LTD

A portable low-temperature plasma device based on a laval nozzle structure and application thereof

PendingCN122075905ASolve the problem of ineffective treatment of skin diseasesgood killing effectOrganic active ingredientsAntimycoticsPlasma jetPlasma technology
This invention discloses a portable low-temperature plasma device based on a Laval nozzle structure and its application, belonging to the field of plasma technology application technology. Specifically, it includes (1) the construction of the device; and (2) the use of the device for fungal eradication treatment and transdermal drug delivery enhancement treatment. The beneficial effects achieved by this invention are as follows: This invention is the first to apply the Laval nozzle structure to a portable low-temperature plasma device. The results show that the device can effectively improve the plasma jet performance and active particle content, significantly improve the treatment effect of fungal infections of the skin and nails and the transdermal drug penetration efficiency, while solving the problems of large size, reliance on external power supply, and complex operation of traditional plasma devices. Therefore, using this invention for the treatment of fungal infections of the skin and nails and for enhanced transdermal drug delivery has advantages such as ease of operation, high safety, non-invasiveness, and high efficiency, and thus has potential application prospects in the field of skin disease treatment and transdermal drug delivery.
Owner:HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES

Refrigerator and control method thereof, refrigeration system

PendingCN122544503Aquick breakdownpromote decomposition
This invention discloses a refrigerator and its control method and refrigeration system. The refrigerator includes at least a low-oxygen preservation system and a sterilization system. The control method includes: when the refrigerator door is closed, detecting whether the refrigerator has activated an oxygen reduction mode; if so, activating the sterilization mode for a first preset time when the time interval since the last activation of the sterilization mode reaches a first threshold time; if not, activating the sterilization system for a second preset time when the time interval since the last activation of the sterilization mode reaches a second threshold time. Compared with the prior art, this invention can achieve rapid ozone accumulation in a short time through oxygen-enriched gas, reducing the operating time of the ion generator, and after the sterilization mode ends, accelerating ozone decomposition through oxygen-enriched gas to reduce the ozone presence time, thus realizing closed-loop control of oxygen-enriched gas reuse, instantaneous high-concentration ozone sterilization, and rapid ozone decomposition.
Owner:GREE ELECTRIC APPLIANCE INC OF ZHUHAI

A method for surface antibacterial functionalization of a medical titanium alloy material

PendingCN122344722AGood tissue penetrationEffective sterilizationHeterojunctionLight irradiation
The application discloses a kind of medical titanium alloy material surface antibacterial functionalization processing methods, first by hydrothermal oxidation and high-temperature sintering processing in titanium alloy material surface construction TiO2 Nanometer sheet, then deposit W 18 O 49 Quantum dots are deposited on the TiO2 Nanometer sheet, and TiO2 / W 18 O 49 Heterojunction is constructed on the surface of titanium alloy.TiO2 / W 18 O 49 Heterojunction can efficiently catalyze the production of reactive oxygen species (ROS) under near-infrared light irradiation, achieving antibacterial function. The TiO2 / W 18 O 49 Heterojunction functionalized titanium alloy material surface, the irregular sheet structure of TiO2 Nanometer sheet can greatly increase the contact area of the material surface and the surrounding solution, and the W 18 O 49 Quantum dots have the characteristics of "single-atom-like catalysis", which can improve the ROS yield and further endow the medical titanium alloy surface with strong photodynamic antibacterial performance.
Owner:HUAIYIN INSTITUTE OF TECHNOLOGY

A wall-mounted air purifier

The utility model provides a kind of hanging air purifier, relate to air purifier technical field.A kind of hanging air purifier, comprising: shell, air inlet and air outlet are provided on shell;Support frame, support frame is set in shell, and first accommodating space is provided in support frame;Filter element, filter element is set in first accommodating space;Plasma generating device, plasma generating device is set in first accommodating space, and filter element is set between plasma generating device and air inlet;Wherein, plasma generating device includes first frame and multiple plasma generating modules set in first frame.By being provided with plasma generating device in hanging air purifier, air is further treated by sterilization, deodorization etc. after passing through physical filtration, improve purification efficiency, and plasma generating device uses modular design to use multiple plasma generating modules, facilitate flexible configuration.
Owner:NINGBO TALLER ELECTRICAL APPLIANCE CO LTD

Campus direct drinking machine with efficient sterilization function

The utility model discloses a campus direct drinking machine with an efficient sterilization function, and relates to the field of direct drinking machines, the campus direct drinking machine with the efficient sterilization function comprises a shell, a filtering system, a heat exchanger, a hot tank and a range extending water tank are installed in the shell, and the liquid outlet end of the filtering system is connected with a cold fluid inlet of the heat exchanger; according to the campus direct drinking machine with the efficient sterilization function, the range-extending water tank is large in water storage space, multiple external water outlets are connected with multiple faucets, water can be stably supplied when teachers and students use water in a centralized mode in a campus, the problem that water is insufficient when multiple faucets of a traditional direct drinking machine are started at the same time is solved, and the water use requirement of a crowded place is met. Meanwhile, a closed-loop sterilization system is formed through a filtering system, a hot tank, an overflowing type uv sterilization lamp, a correlation uv lamp in a range extending water tank and silver ions at a water nozzle, microorganisms in water are efficiently killed, the safety of drinking water is guaranteed, and the health of teachers and students is protected.
Owner:HEFEI SHIHONG PURIFICATION TECH CO LTD

Water circuit board assembly and drinking water equipment

ActiveCN224639509UEffective sterilizationGuaranteed temperature stability
This utility model relates to the field of drinking water equipment technology, and discloses a water circuit board assembly and drinking water equipment. The water circuit board assembly includes: a lower water circuit board for installing the cooling component and the heating element, and connecting the water tank and the heating element through the lower water circuit board; a water tank water circuit board, integrated into and connected to the water tank, and installed and connected above the cooling component; the water tank water circuit board is connected to the heating element. The lower water circuit board and the water tank water circuit board provided by this utility model adopt integrated water circuit board module and modular design respectively, which not only improves the system sealing and stability of the drinking water equipment, but also simplifies the assembly process of the drinking water equipment and improves the production efficiency of the drinking water equipment. Furthermore, the modular design of the drinking water equipment makes maintenance and upgrades more convenient, and also solves the problems of odor, complex assembly, and low safety caused by messy pipelines in traditional drinking water equipment using silicone tubing.
Owner:GREE ELECTRIC APPLIANCE INC OF ZHUHAI

High-temperature sterilization equipment for fresh corn processing

The invention belongs to the technical field of fresh corn sterilization processing, and particularly relates to high-temperature sterilization equipment for fresh corn processing, which comprises a screening mechanism, the screening mechanism is placed on the ground, the screening mechanism screens and discharges corn leaves and particles, and the inner center of the screening mechanism is rotatably connected with an auxiliary mechanism. The auxiliary mechanism is used for carrying out pressing and steam sterilization operation on the corn on the inner wall of the corn processing mechanism, and the auxiliary mechanism and the corn processing mechanism rotate reversely, so that deviation-free stable positioning in the fresh corn processing process is realized, and meanwhile, circulating airflow is formed in the equipment to assist in air drying; the defects that a traditional device is prone to deviation in corn rotary processing, dead angles exist in leaf peeling and sterilization, and the air drying efficiency is low are overcome.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI

Vacuum sterilization structure for sealing bottle cap

ActiveCN224477923UEnter correctlyreduce wasteGas cylinderWater circulation
The utility model relate to a bottle lid sealing vacuum sterilization structure, the utility model discloses a machine body, the machine body is equipped with the conveyor belt to deliver container jar, and is equipped with the machine base in corresponding position, and the machine base is equipped with a container lid guide unit, the rear side of machine base is equipped with the steam guide seat, and forms a steam guide groove, and the high temperature gas supply pipe spare of the intercommunication vacuum sterilization unit, the vacuum sterilization unit further includes compressed gas cylinder, steam supply pipeline and hot water circulation system to maintain stable steam supply and condensate recovery, combining container lid feeding cylinder, container lid adjusting unit and control unit, realize the automation process of lid material supply, right positioning, steam sterilization and sealing press -fit, the utility model can effectively improve the sterilization efficiency, prolong the product shelf life, and have the practical progress nature of energy -conserving and efficient production.
Owner:廖家培

Improved membrane electrode and preparation and application method thereof

The invention discloses an improved membrane electrode and a preparation and application method thereof. The improved membrane electrode comprises polyvinyl alcohol-activated carbon as a basic electrode, and a bimetallic doped carbon-based catalyst and a porous carbon-based catalyst which are respectively positioned on two sides of the basic electrode and are used as an anode and a cathode. Activated carbon is used as a catalytic membrane electrode base material, polyvinyl alcohol is used as a binder to prepare PVA-AC, a catalyst is loaded to the PVA-AC based on bimetallic blending, high-temperature pyrolysis and electrostatic spinning to prepare an electro-catalytic anode with excellent oxidation-reduction performance, and an electro-catalytic cathode is prepared based on high-temperature pyrolysis and electrostatic spinning. And an aeration device is further introduced to construct the CDI system.
Owner:SHANGHAI JIAOTONG UNIV

An antibacterial antiviral agent, its method of preparation and use in sanitizing wipes

The application discloses an antibacterial and antiviral agent, which comprises the following components in parts by weight: 100 parts of water, 0.04-0.1 parts of cetylpyridinium chloride, 0.2-0.6 parts of benzalkonium chloride, 0.1-0.3 parts of polyhexamethylene biguanide hydrochloride, 0.04-0.16 parts of phenoxyethanol, 0.5-5 parts of silica-supported metal silver nanoparticles, 0.4-1.0 parts of propylene glycol, 0.02-0.06 parts of glycerol and 0.02-0.06 parts of EDTA-2Na. The application further discloses a preparation method of the antibacterial and antiviral agent. The antibacterial and antiviral agent provided by the application can synergistically enhance the effect by compounding cetylpyridinium chloride, benzalkonium chloride, polyhexamethylene biguanide hydrochloride and silica-supported metal silver nanoparticles, reduces the active ingredients such as cetylpyridinium chloride and benzalkonium chloride, and maintains excellent bactericidal effect; and the combination of silica-supported metal silver nanoparticles with different particle sizes enables the sanitary wet wipe liquid to not only quickly kill bacteria but also kill bacteria for a long time, and effectively improves the bactericidal efficiency and bactericidal timeliness of the sanitary wet wipe liquid.
Owner:SHANGHAI MIAOYOU PHARMACEUTICAL TECHNOLOGY CO LTD +1

An electrolysis water device

ActiveCN120964957BImprove reaction kineticsImprove production efficiency
The application discloses an electrolytic water device. The electrolytic water device comprises a shell, a cathode and an anode; the shell has a cavity inside, and water inlets and outlets are arranged on opposite surfaces of the shell; wherein the diameter of the water inlet is larger than that of the water outlet; the cathode and the anode are arranged in the cavity, and extend along the direction from the water inlet to the water outlet; the two ends of the anode in the extending direction are fixed to the inner wall of the shell; the cathode and the anode are both in the form of a sheet, and the anode and the cathode are arranged in a stacked manner with a spacing, and the sheet surface of the anode protrudes towards the cathode. The sheet anode with a curved surface structure is constructed in the embodiment of the application, the anode and the cathode are arranged in a stacked manner with a spacing, a water flow channel similar to a Venturi structure with a narrow middle and wide ends is formed, the ionization activity can be improved at the electric field concentration, and the turbulent flow can be formed at the two ends to quickly take the bubbles away from the electrode surface, so that the water with a wide TDS value can be effectively electrolyzed, and the disinfection and sterilization requirement can be met.
Owner:JOMOO KITCHEN & BATHROOM

A FeN-T nanozyme composite material, its preparation method and application

PendingCN122557594Agood biocompatibilityInhibit excessive inflammatory response
This invention discloses a FeN-T nanozyme composite material, its preparation method, and its applications, belonging to the field of pharmaceutical formulation technology. The FeN-T nanozyme composite material is composed of iron-based nanozyme, tacrolimus, and polylactic-co-glycolic acid copolymer. This invention prepares the nanozyme composite material (FeN-T) by encapsulating iron-based nanozyme (FeN) with the anti-inflammatory drug tacrolimus (TAC) using PLGA. Experimental verification shows that FeN-T can promote cell migration and has almost no cytotoxicity at effective therapeutic concentrations; it can also improve the antibacterial rate of H2O2; simultaneously, the combined treatment of FeN-T and H2O2 achieves a wound healing rate of 95% within 9 days, significantly better than single treatment. Therefore, this invention provides a multifunctional composite material with highly efficient antibacterial, good biocompatibility, and anti-inflammatory and repair-promoting functions.
Owner:SOUTHWEST UNIVERSITY FOR NATIONALITIES

Intelligent dynamic sterilization water tank

ActiveCN224646731UEffective sterilizationSterilization process without dead corners
The utility model provides an intelligent dynamic sterilization water tank, including water tank, float ball, UV LED lamp strip and electric control board, its characterized in be that the water tank central arrangement vertical float ball support, the float ball support adopts transparent ABS material to make, built-in segmented type UV LED lamp strip, in the float ball support according to height high position, middle position, low position is equipped with three sensors, is equipped with float ball in the periphery of float ball support, is equipped with permanent magnet of trigger sensor in the float ball, the utility model relates to an intelligent dynamic sterilization water tank is through the hall switch of cooperation trigger of float ball and float ball support, segmented type control UV LED lamp of setting therein starts off, according to the ultraviolet light of liquid level's floating adjustment control is killed, energy -conserving and environmental protection, ensures the efficient, germicidal process of no dead angle.
Owner:SHENZHEN ANGEL DRINKING WATER IND GRP

Klebsiella pneumoniae bacteriophage and application thereof

The invention belongs to the technical field of microorganisms, and particularly relates to a klebsiella pneumoniae bacteriophage and application thereof.The klebsiella pneumoniae bacteriophage is named as vBKpnSP14 and preserved in the China General Microbiological Culture Collection Center on September 17, 2025, and the preservation number is CGMCC NO.46679. The klebsiella pneumoniae bacteriophage vBKpnSP14 has the high cracking rate on klebsiella pneumoniae, and the klebsiella pneumoniae bacteriophage vBKpnSP14 has the advantages that the klebsiella pneumoniae bacteriophage vBKpnSP14 has the high cracking rate on klebsiella pneumoniae; the bacteriophage has an effect of cracking klebsiella pneumoniae and edwardsiella tarda, has a cross-species cracking characteristic, and can solve the problem that in the prior art, a bacteriophage capable of cracking klebsiella pneumoniae and edwardsiella tarda at the same time lacks.
Owner:LIAOCHENG UNIV

A high-temperature sterilization device for pre-prepared food processing

This utility model relates to the field of high-temperature sterilization equipment technology, and discloses a high-temperature sterilization device for pre-prepared food processing, including: a high-temperature sterilization tank and a top cover plate. The top surface of the high-temperature sterilization tank has equidistantly distributed heat-conducting pipe mounting holes. The top surface of the top cover plate has a feed inlet, and a sealing cover plate is fixedly connected to the top of the feed inlet. A bottom heat-conducting cavity is fixedly connected to the bottom surface of the high-temperature sterilization tank, and a top transfer cavity is fixedly connected to the top surface of the top transfer cavity. A sterilization stirring assembly is disposed inside the high-temperature sterilization tank and inside the top of the top cover plate. A high-temperature sterilization heating assembly is disposed on the side of the bottom heat-conducting cavity at the bottom of the high-temperature sterilization tank. A water vapor cooling and reflux assembly is disposed on the side of the top transfer cavity at the top of the high-temperature sterilization tank. This utility model uses multiple components for synergistic sterilization, and the stirring rod agitates the food to ensure uniform steam contact, achieving comprehensive sterilization.
Owner:重庆登娃食品开发有限公司

Container sterilization method, container sterilization device, and content filling system

A container sterilization method, a container sterilization device, and a content filling system. The container sterilization method of the present invention has: a conveying step of conveying a container (100) having a mouth portion (110) filled with a content; a nozzle insertion step of inserting a nozzle (90) for spraying a sterilizing agent into the container (100) being conveyed; a sterilizing agent supply step of supplying the sterilizing agent to the container (100) into which the nozzle (90) is inserted; and a top surface sterilization step of spraying the sterilizing agent from the nozzle (90) to a top surface (115) of the mouth portion (110) of the container (100) at least one of before the nozzle insertion step and after the sterilizing agent supply step.
Owner:DAI NIPPON PRINTING CO LTD

Silicone rubber sheath material for power cable and preparation method of silicone rubber sheath material

PendingCN121851715AIncrease layer spacingHigh flame retardant and smoke suppression efficiencyRubber insulatorsClimate change adaptationHexagonal boron nitrideTetrazole
The invention relates to the field of silicone rubber, and discloses a silicone rubber sheath material for power cables and a preparation method thereof, the sheath material comprises silicone rubber, modified graphene oxide, a composite filler, a vulcanizing agent and a lubricant; the modified graphene oxide is prepared by reacting a cyclotriphosphazene derivative with isocyanated graphene oxide and then coordinating the obtained functionalized graphene oxide with copper ions; the cyclotriphosphazene derivative is prepared by the following steps: reacting hexachlorocyclotriphosphazene with 5-aminotetrazole, then continuously reacting with 2-amino-1H-imidazole-5-formaldehyde, and carrying out addition on a prepared Schiff base cyclotriphosphazene substituent and DOPO (9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide). The composite filler is prepared by stripping and functionalizing hexagonal boron nitride by using sodium hydroxide and then loading zinc oxide on the hexagonal boron nitride through in-situ synthesis, and by adding the modified graphene oxide and the composite filler, the silicone rubber sheath material is endowed with excellent mechanical properties, flame retardance and antibacterial properties.
Owner:广州环城电缆有限公司

Microneedle patch for closed-loop management of drug-resistant bacteria infected wounds of animals as well as preparation method and application of microneedle patch

The invention provides a microneedle patch for closed-loop management of drug-resistant bacteria infected wounds of animals as well as a preparation method and application of the microneedle patch. According to the micro-needle patch, silk fibroin / hyaluronic acid composite hydrogel serves as a matrix, silver nanorods with specific local surface plasmon resonance (LSPR) characteristics are loaded, and wound pH real-time monitoring and near-infrared two-zone (NIR-II) photo-thermal sterilization functions based on surface enhanced Raman spectroscopy (SERS) can be achieved. The microneedle structure can penetrate into the deep layer of the wound, and precise delivery and treatment are achieved. According to the invention, monitoring and treatment are integrated, a closed-loop management system is formed, and the diagnosis and treatment efficiency and healing quality of wounds infected by drug-resistant bacteria of animals are remarkably improved. The patch has good wound pH monitoring ability, antibacterial effect and wound healing ability, and an efficient and safe solution is provided for treatment of drug-resistant bacteria wounds of animals.
Owner:ZJU HANGZHOU GLOBAL SCI & TECH INNOVATION CENT

Enzyme-triggered self-assembling peptide hydrogel, preparation method and application thereof

PendingCN122251319Aavoid secondary stimulationAchieve in-situ gelationOrganic active ingredientsAntibacterial agentsEngineeringStaphylococcus aureus
The application discloses an enzyme-triggered self-assembly peptide hydrogel, a preparation method and application thereof, and belongs to the technical field of biomedical materials. The hydrogel comprises a peptide precursor Nap-YY(p)Y, an antibacterial compound daphnodorin and alkaline phosphatase; the peptide precursor is dephosphorylated under the action of the alkaline phosphatase, self-assembled to form a nanofiber network structure, and encapsulates the daphnodorin in the network structure. The hydrogel has a short gelation time (3-10 minutes), a moderate mechanical strength (a storage modulus G' of 130-170 Pa), a high encapsulation rate (greater than or equal to 75%), presents a biphasic release characteristic in a simulated wound liquid, and can maintain an effective therapeutic concentration for more than 7 days. The hydrogel has a significant synergistic killing effect on methicillin-resistant Staphylococcus aureus and a biofilm thereof, can effectively reduce a bacterial load of a wound and accelerate wound healing.
Owner:TIANJIN CHEST HOSPITAL

Sterilizing pot for food processing

ActiveCN224250652UEnsure commercial sterility requirementsEnsure food meets commercial sterility requirementsFood shapingMechanical engineeringFood processing
The utility model discloses a sterilization pot for food processing. The sterilization pot comprises a sterilization kettle, a heating tank and a spraying pipeline system. Rotary spraying arms are evenly distributed at the bottom of a spraying water inlet pipe in the sterilization kettle and composed of branch pipes, rotary supporting frames and spraying pipes, the spraying pipes are communicated with the branch pipes through auxiliary pipes, driving nozzles are arranged on the peripheries of the spraying pipes, spraying holes are formed in the bottoms of the spraying pipes, and acute angles are formed between the spraying directions of the driving nozzles and the radial direction of a circular ring. And a spiral coil type heat exchanger is arranged in the heating tank. The sterilization pot is uniform in spraying, high in heat exchange efficiency, high in steam utilization rate, low in energy consumption and capable of meeting the requirement for accurate sterilization of food.
Owner:HUIRU (SHANDONG) BIOTECHNOLOGY CO LTD

An injectable hydrogel for photothermal-assisted treatment of periodontitis and its preparation method

ActiveCN121337987BExcellent photothermal performanceEffective antibacterialAntibacterial agentsOrganic active ingredientsCarboxymethyl-chitosanAntibacterial property
This invention discloses an injectable hydrogel for photothermal-assisted treatment of periodontitis and its preparation method, belonging to the field of polymer material preparation technology. The preparation method includes the following steps: reacting MXene dispersion with epigallocatechin gallate and MgSO4; then sequentially performing ultrasonication, centrifugation, washing, and lyophilization to obtain multifunctional nanosheets MP-Mg; adding the multifunctional nanosheets MP-Mg to an aqueous solution of oxidized gellan gum for mixing to obtain solution A; mixing equal volumes of quaternary ammonium chitosan aqueous solution and carboxymethyl chitosan aqueous solution for reaction to obtain solution B; and mixing equal volumes of solution A and solution B for further reaction. The hydrogel prepared by this invention possesses injectability, photothermal responsiveness, biofilm penetration ability, synergistic antibacterial properties, and long-lasting anti-inflammatory effects, providing an innovative and practical photothermal-assisted treatment platform for the clinical treatment of periodontitis.
Owner:JILIN UNIVERSITY

A type of aquarium lighting lamp

ActiveCN224267897Uextended stayHigh killing efficiencyPisciculture and aquariaAquarium lightingBacterial virus
This utility model discloses an aquarium lighting lamp, including a UV lamp assembly and an external assembly. The UV lamp assembly includes a lampshade, with a spiral flow channel installed on the inner side wall of the lampshade, a lamp tube base installed on the inner bottom wall of the lampshade, and a UV lamp body installed on the inner side wall of the lamp tube base. Through the spiral flow channel, the water enters from the top inlet pipe and, instead of flowing directly and quickly through the lampshade, is forced to flow downwards along a spiral path. This significantly prolongs the residence time of the water within the effective irradiation area of ​​the UV lamp body, thereby significantly improving the killing efficiency against various bacteria, viruses, and algal spores, achieving deep and efficient sterilization. Furthermore, the UV lamp body is completely sealed inside the lampshade, preventing ultraviolet rays from directly irradiating the aquarium water, thus completely avoiding potential damage to the eyes, skin, and cell tissues of fish.
Owner:赵昕宇

Compounds targeting inhibition of aspartate transcarbamylase and their use in gram-positive bacterial infections

This invention belongs to the field of biomedical technology, specifically relating to compounds that target and inhibit aspartate transcarbamate and their application in Gram-positive bacterial infections. It features a simple synthesis method, enabling mass production of the active compound through easily scalable conventional chemical reactions; significantly enhanced antibacterial activity: a highly efficient bactericidal compound with activity superior to existing clinical drugs like vancomycin; effective removal of mature biofilms of MRSA and effective killing of bacteria within the mature biofilm, exhibiting significant anti-biofilm activity; and good safety: no potential risk of hemolytic reactions, low toxicity, and no carcinogenic, teratogenic, or mutagenic toxicity.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS