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46 results about "Andrographis" patented technology

Andrographis is a genus of flowering plants in the family Acanthaceae. They may be known generally as the false waterwillows, and several are called periyanagai. Most species are native to Asia. Many are endemic to India. They may be herbs or shrubs.

Plant extract composition with anti-inflammatory and soothing effects and preparation method thereof

The invention relates to the technical field of natural plant extracts, and particularly discloses a plant extract composition with anti-inflammatory and soothing effects and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in percentage by weight: 1 to 5 percent of radix cynanchi atrati extract, 1 to 3 percent of flos magnoliae extract, 1 to 5 percent of flos hibisci mutabilis extract, 0.5 to 1 percent of herba andrographitis extract, 1 to 3 percent of citrus peel extract, 0.5 to 1 percent of rhizoma paridis extract and the balance of solvent. Six plant extracts with different anti-inflammatory mechanisms are scientifically screened and proportioned, the extraction process is optimized, the plant extracts have a synergistic effect, and the anti-inflammatory effect is improved by adjusting the proportion; the six components respectively act on different links of inflammatory response to form a complementary anti-inflammatory network, the plant extract composition with multiple anti-inflammatory pathways and synergistic interaction is developed, and the problems of single anti-inflammatory effect, insufficient permeability and the like in the prior art are solved.
Owner:GUANGDONG FANYIN NEW MATERIALS CO LTD

Traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application of traditional Chinese medicine composition

The invention relates to a traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material medicines in parts by mass: 50-200 parts of silybum marianum, 50-200 parts of schisandra chinensis, 50-200 parts of gentiana macrophylla, 50-200 parts of andrographis paniculata, 50-200 parts of radix paeoniae alba, 50-200 parts of oldenlandia diffusa, 50-200 parts of folium isatidis and 50-200 parts of patrinia. The traditional Chinese medicine composition has the effects of resisting endotoxin, inflammation, allergy and liver injury and the like, and effectively prevents and treats the liver rupture syndrome of the broiler breeders.
Owner:淄博维希尔生物技术有限公司

Medicinal composition for antibacterial and anti-inflammatory effect using combination of chinese herbal medicine and marine extract

The present application relates to the field of pharmacy, disclose the medicine composition for antibacterial and anti-inflammatory of Chinese herbal medicine and marine extract combination, including: baicalin extract 5~10 parts; andrographolide extract 3~7 parts; sulfated fucoidan 2~5 parts; spongin extract 0.2~1 part; wherein: baicalin extract is derived from the root of scrophulariaceae, is extracted by ethanol-water mixed solvent; andrographolide extract is derived from the whole plant of andrographis, is extracted by ethanol-water mixed solvent; sulfated fucoidan is derived from brown algae, is prepared by enzymolysis and alcohol precipitation method; spongin extract is derived from sponges, is extracted and separated and purified by organic solvent. Through the technical scheme of the synergistic combination of active ingredients of Chinese herbal medicine and marine extract, the technical effect of destroying the biofilm barrier and clearing the stubborn infection focus in the treatment of bacterial vaginitis, candida vaginitis and cervical inflammation associated with biofilm infection is achieved.
Owner:ZHENGZHOU LIFE ORIGIN TECHNOLOGY CO LTD

Anti-saccharification composition applicable to sensitive skin and application of anti-saccharification composition

PendingCN122005402ACosmetic preparationsToilet preparationsPanax ginseng root extractSkin elasticity
The invention relates to an anti-saccharification composition applicable to sensitive skin and application, and belongs to the technical field of cosmetics. The anti-saccharification composition suitable for sensitive skin is prepared from the following components in parts by mass: 0.01 to 0.5 part of ascorbic acid polypeptide, 0.5 to 2 parts of ginseng root extract, 0.1 to 2 parts of acetyl tetrapeptide-2 and 0.1 to 5 parts of herba andrographitis leaf extract. The anti-saccharification composition suitable for the sensitive skin, provided by the invention, has a remarkable anti-saccharification effect, can remarkably improve skin elasticity, has a certain repairing effect and is suitable for the sensitive skin.
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Chinese herbal medicine superfine powder feed additive and preparation method thereof

The invention relates to the technical field of feed additives, in particular to a Chinese herbal medicine ultrafine powder feed additive and a preparation method thereof, the following raw materials are respectively weighed: codonopsis pilosula, acanthopanax, hawthorn, andrographis paniculata, citric acid, catechin, L-ascorbyl palmitate and reduced glutathione; immersing the codonopsis pilosula sections, the acanthopanax sections and the haw slices into enzymatic hydrolysate to carry out enzymatic hydrolysis reaction; crushing the codonopsis pilosula, the acanthopanax, the hawthorn and the andrographis paniculata sections subjected to enzymolysis by using a hammer crusher to obtain mixed powder; adding citric acid, catechin, L-ascorbyl palmitate and reduced glutathione, and mixing; the mixture is subjected to superfine grinding through a jet mill, and superfine powder is obtained; and mixing the superfine powder with hydroxypropyl-beta-cyclodextrin, adding water to prepare slurry, stirring and clathrating, and then carrying out spray drying to obtain the Chinese herbal medicine superfine powder feed additive.
Owner:WEIFANG TIANJIAN YUANXIN AGRI TECH CO LTD

Compound traditional Chinese medicine preparation for targeting egg drop syndrome of duck and goose

PendingCN122321083ABiotechnologyDisease
The application relates to the technical field of traditional Chinese medicine preparation, and particularly discloses a compound traditional Chinese medicine preparation for targeting egg duck and goose egg cytoplasmic disease, which comprises the following components: white head, Coptis chinensis, Huangqi, Phellodendron amurense, wine Danpi, bran-fried peach kernel, Chinese perilla, pomegranate peel, liquorice, honeysuckle, Andrographis, figwort, emblic, ginger, fried atractylodes, fried safflower, Xianhecao, spiny amaranth, and Poria cocos. Through the combination of monarch, minister, assistant and messenger, the core effects of heat-clearing and detoxifying, blood-cooling and dysentery-stopping, and dampness-drying and insect-killing of the medicines are synergistically exerted, the pathogenesis characteristics of the egg cytoplasmic disease are accurately targeted, blood stasis and blood circulation are promoted to eliminate the swelling of the lesion, and the intestinal mucosa damage is repaired to stop bleeding, the symptoms of hematochezia, diarrhea and oviduct inflammation of the egg duck and goose caused by the egg cytoplasmic disease are effectively relieved, the problems of the decreased antibiotic effect, drug residue, bacterial flora disorder and food safety risk are effectively solved, and the compound traditional Chinese medicine preparation has the remarkable progress of drug resistance, safety, no residue, intestinal protection and green environmental protection.
Owner:JINMUTANG BIOTECHNOLOGY (TEXAS) CO LTD

Preparation method of Ganmaoqing capsule

The invention belongs to the technical field of medicine preparation, and provides a preparation method of a Ganmaoqing capsule. The preparation method comprises the following steps: preparing a Ganmaoqing extract; then totally mixing the cold clearing dry extract, acetaminophen, herba andrographitis leaf powder, moroxydine hydrochloride, chlorpheniramine maleate and talcum powder to obtain medicinal powder; and filling the medicine powder into hollow capsules to obtain the traditional Chinese medicine composition. According to the preparation method disclosed by the invention, sterilization is carried out for 15-20 minutes at 121 DEG C when the raw medicinal powder, namely the andrographis paniculata leaf powder is prepared, so that the microbial limit of the andrographis paniculata leaf powder meets the requirement, and the microbial limit of the Ganmaoqing capsules meets the requirement when the andrographis paniculata leaf powder is used for preparing the Meanwhile, the Ganmaoqing dry extract, the acetaminophen, the common andrographis herb leaf powder, the moroxydine hydrochloride, the chlorpheniramine maleate and the talcum powder are totally mixed for 25-35 min in a three-dimensional motion mixer under the condition of 6.5 r / min, the uniformity of the chlorpheniramine maleate in the Ganmaoqing capsule is improved, and the quality stability of the Ganmaoqing capsule is improved.
Owner:FUJIAN JUSHEN PHARM CO LTD

Veterinary traditional Chinese medicine oral liquid for treating chicken proventriculitis and enteritis and preparation method thereof

The invention belongs to the field of veterinary traditional Chinese medicines, and particularly relates to a veterinary traditional Chinese medicine oral liquid for treating chicken proventriculitis and enteritis and a preparation method thereof. The veterinary traditional Chinese medicine oral liquid for treating chicken proventriculitis and enteritis is prepared from the following raw materials: 20 to 25 parts of radix astragali seu hedysari, 8 to 12 parts of rhizoma atractylodis macrocephalae, 8 to 12 parts of radix sophorae flavescentis extract, 15 to 20 parts of herba andrographitis, 12 to 18 parts of rhizoma polygoni cuspidati, 10 to 15 parts of radix sanguisorbae, 10 to 15 parts of cortex ailanthi and 5 to 10 parts of radix glycyrrhizae. The veterinary traditional Chinese medicine oral liquid for treating chicken proventriculitis and enteritis has the advantages of definite curative effect, small side effect, convenience in use and the like, and the preparation method is simple and feasible, low in cost and convenient for large-scale popularization and application.
Owner:SHANDONG HUAJUN BIOPHARMACEUTICAL CO LTD

Application of traditional Chinese medicine composition in preparation of medicine for preventing and / or treating heart failure

The invention provides application of a traditional Chinese medicine composition in preparation of a medicine for preventing and / or treating heart failure. The traditional Chinese medicine composition comprises glechoma longituba, rumex madaio, saxifraga stolonifera, sabia parviflora, phoenix-tail fern, scutellaria baicalensis, golden cypress and andrographis paniculata. The mass ratio of the glechoma longituba to the nepal dock root to the saxifraga stolonifera to the sabia parviflora to the phoenix-tail fern to the scutellaria baicalensis to the golden cypress to the common andrographis herb is (30-54): (39-45): (34-47): (24-67): (26-62): (26-62): (24-67): (30-54). According to the traditional Chinese medicine composition, various traditional Chinese medicine components are matched for use, heart failure can be effectively treated, and the heart function of a patient is improved.
Owner:GUANGZHOU XITAO BIOMEDICAL TECHNOLOGY CO LTD +1

Traditional Chinese medicine formula for treating haemorrhoids and preparation method thereof

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine formula for treating haemorrhoids and a preparation method thereof. The formula comprises ephedra, semen brassicae, cinnamon, rhizoma zingiberis, antler slices, bombyx batryticatus, smoked plum, catechu, golden cypress, coix seeds, peach kernels, snakegourd seeds, sanguisorba officinalis, hairyvein agrimony, radix angelicae, purslane, red halloysite, dragon's blood, gallnut, andrographolide extract and carboxymethyl pachymaran, and preferably comprises sophora flowers and fructus aurantii. The preparation method comprises the following steps: firstly, carrying out physical field auxiliary activation on animal and mineral medicinal materials in the formula, carrying out synergistic aging on high-tannin medicinal materials, and carrying out co-crushing pretreatment on sophora flowers and fructus aurantii; carrying out alternating magnetic field assisted dynamic countercurrent extraction on the pretreated medicinal materials; carrying out membrane separation and refining on an extracting solution, and carrying out oriented assembly on the refined extracting solution, an andrographolide extract and carboxymethyl pachymaran; and finally carrying out programmed molding according to the requirements of oral solid preparations or decoctions. The composition can be used for treating haemorrhoids, and has the advantages that multiple components have a synergistic effect, and related symptoms of the haemorrhoids can be conditioned in a targeted manner.
Owner:康奇元

Andrographolide purification device

The utility model relates to the technical field of andrographolide cleaning, and discloses an andrographolide purifying device which comprises a cleaning box and a transverse plate, a flexible net belt is sleeved on an outer ring between rotating rollers on two sides in a transmission mode, and flexible side nets are fixed on outer rings of the front end and the rear end of the flexible net belt in a surrounding mode. A plurality of separation nets are evenly and longitudinally fixed between the front-end flexible side net and the rear-end flexible side net, a spraying pipe is longitudinally fixed in the cleaning box above the flexible net belt, and a plurality of electric heating nets are evenly and longitudinally fixed between the front-end vertical plate and the rear-end vertical plate. According to the technical scheme, the flexible net belt provided with the flexible side net and the separation net is driven to rotate inside and above the cleaning box, andrographolide can be placed on the surface of the flexible net belt between the separation net and the flexible side net to be conveyed, the andrographolide is cleaned through clean water sprayed by the spray heads of the spray pipe, and the cleaning efficiency is improved. The andrographolide is conveyed to the upper portion and then heated and dried by the electric heating net, waste heat generated after drying can heat clean water, it is guaranteed that andrographolide is efficiently and cleanly cleaned, and then direct storage is facilitated.
Owner:GUIZHOU DEGUANG CHINESE MEDICINAL MATERIALS CO LTD

Traditional Chinese medicine composition for superficial thrombophlebitis, preparation and preparation method thereof

PendingCN121313771ABlood disorderLeech/worm material medical ingredientsSuppurative thrombophlebitisMyrrh
The invention relates to the technical field of traditional Chinese medicines, provides a traditional Chinese medicine composition for superficial thrombophlebitis, a preparation and a preparation method thereof, and can reduce recurrence of superficial thrombophlebitis after treatment. The composition is composed of the following raw materials: 10-14 g of pseudo-ginseng; 12 to 18g of radix salviae miltiorrhizae; 12 to 18g of rhizoma corydalis; 10 to 14g of radix curcumae; 8 to 12g of curcuma zedoary; 12 to 18g of herba andrographitis; 8 to 12g of frankincense; 8 to 12 g of myrrh; 22-28 g of radix clematidis; 12 to 18g of radix paeoniae rubra; 18-22g of longhairy antenoron herb; 12 to 18g of ligusticum wallichii; 22 to 28g of fructus forsythiae; 10 to 14g of pawpaw; 2-4g of leech; and 10-14g of Chinese angelica.
Owner:WUXI NO 9 PEOPLES HOSPITAL

Traditional Chinese medicine composition for preventing and treating fish enteritis as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for preventing and treating fish enteritis. The traditional Chinese medicine composition is prepared from 10-50 parts of rheum officinale, 10-30 parts of origanum vulgare, 10-30 parts of herba andrographitis, 10-30 parts of humifuse euphorbia herb, 5-20 parts of radix aucklandiae and 5-20 parts of rhizoma smilacis glabrae. The corresponding preparation method comprises the following steps: stir-frying the rheum officinale with yellow wine, and stir-frying half of the radix aucklandiae with bran; all the components are weighed according to the formula and smashed to obtain traditional Chinese medicine composition powder, or all the components are weighed according to the formula, extracted and concentrated to be prepared into traditional Chinese medicine composition oral liquid, granules, extract powder or tablets. The invention relates to application in preparation of medicine-containing feed or medicine for preventing and treating fish enteritis. The traditional Chinese medicine composition has a good prevention and treatment effect on bacterial enteritis of fishes, can improve the immune function and disease resistance of the fishes, relieve inflammatory response caused by pathogenic infection, delay the morbidity process of fish enteritis caused by pathogenic bacteria and reduce the death rate of the fishes, and also can improve the feed intake of the fishes, reduce the feed coefficient and effectively improve the production performance.
Owner:YELLOW SEA FISHERIES RES INST CHINESE ACAD OF FISHERIES SCI

Traditional Chinese medicine hair lotion capable of removing dandruff, relieving itching, controlling oil and preventing alopecia and preparation method of traditional Chinese medicine hair lotion

The invention belongs to the technical field of wash supplies, and particularly relates to a traditional Chinese medicine hair lotion capable of removing dandruff, relieving itching, controlling oil and preventing alopecia and a preparation method of the traditional Chinese medicine hair lotion. The traditional Chinese medicine composition comprises eichhornia crassipes, ludwigia hyssopifolia, trichosanthes cucumeroides, green plums, Wuzmann grass, longan leaves, elm barks, Hainan tea cakes, Chinese honeylocust fruits, dracaena longipedunculata roots, cacumen biotae, folium mori, adenosma indianum leaves, yellow carex leaves, radix sophorae flavescentis, radix paeoniae alba, zingiber cochinchinensis leaves, herba andrographitis, erythrina indica leaves, ardisia macrorrhiza tender leaves and schisandra chinensis. The traditional Chinese medicines are combined, and the problems of dandruff, pruritus, oily head and alopecia can be specifically solved through the four-dimensional synergistic effect of resisting bacteria, relieving itching, regulating grease, promoting circulation and nourishing hair follicles.
Owner:HAINAN MEDICAL UNIV

Traditional Chinese veterinary medicine for accelerating feed intake recovery of poultry after illness and preparation method of traditional Chinese veterinary medicine

The invention belongs to the technical field of poultry breeding, and particularly relates to a traditional Chinese veterinary medicine for accelerating recovery of feed intake of poultry after illness, the traditional Chinese veterinary medicine is prepared from the following raw medicinal materials in parts by weight: 10-26 parts of rice sprout, 10-26 parts of gynostemma pentaphylla, 5-15 parts of tuber fleeceflower stem, 10-22 parts of radix bupleuri, 5-15 parts of radix aconiti carmichaeli, 10-35 parts of galangal, 10-22 parts of andrographis paniculata and 5-16 parts of liquorice. According to the traditional Chinese veterinary medicine for accelerating the recovery of the feed intake of the poultry after the disease and the preparation method of the traditional Chinese veterinary medicine, the rice sprout, the gynostemma pentaphylla, the tuber fleeceflower stem, the radix bupleuri, the radix aconiti carmichaeli, the rhizoma galangae, the herba andrographitis and the liquorice are added, and a plurality of Chinese herbal medicine raw medicinal materials are combined according to a proposed proportion and can complement each other and have a synergistic effect, so that the respective medicinal effects are exerted to the maximum extent; the multiple medicinal materials are mixed to achieve a synergistic effect, the spleen, stomach, heart and kidney functions of the poultry are comprehensively conditioned, the recovery efficiency of food consumption after diseases is further improved, and compared with chemical medicines, traditional Chinese veterinary medicines have the advantages of being small in side effect, few in residue and the like by selecting traditional Chinese medicines to be mixed and matched with the chemical medicines.
Owner:SHANGQIU MEILAN BIOENGINEERING CO LTD

A compound preparation of traditional Chinese medicine and additive for treating adenitis of laying hens and application thereof

The application relates to a traditional Chinese medicine and additive compound preparation for treating gizzarditis of laying hens and application, and relates to the technical field of veterinary drugs. The compound preparation is prepared by mixing a traditional Chinese medicine extract and a functional feed additive. The raw material composition of the traditional Chinese medicine extract comprises torrefied malt, torrefied medicated leaven, radix codonopsis, rhizoma atractylodis macrocephalae, rhizoma coptidis, andrographis, dried tangerine or orange peel, white arillus, and liquorice. The additive comprises neutral protease, a mould inhibitor and probiotics. The mould inhibitor is selected from aspergillus flavus B1 degrading enzyme, corn strobukenone degrading enzyme, fumonisin degrading enzyme and vomitoxin degrading enzyme. The probiotics are selected from lactobacillus plantarum, bacillus subtilis and fructo-oligosaccharide. The application is based on the traditional Chinese veterinary theory of food digestion and spleen health, dampness expelling and qi regulation, heat clearing and toxin resolving and mucosa repairing. In combination with the effects of the additive on digestion, mould expelling and intestinal micro-ecological regulation, the application has a remarkable treatment effect on gizzarditis of laying hens, can improve the feed intake and weight gain, reduce the gizzard index, promote the repair of gastric mucosa, and has no antibiotic residue and no toxic side effect.
Owner:XINXIANG HEXIE ANIMAL PHARM CO LTD

Traditional Chinese medicine composition for treating liver cancer and intestinal cancer as well as preparation method and detection method thereof

The invention relates to the field of traditional Chinese medicine preparations and the technical field of medicine analysis, in particular to a traditional Chinese medicine composition for treating liver cancer and intestinal cancer and a preparation method and a detection method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 200 to 300 parts of herba taraxaci, 200 to 300 parts of herba rabdosiae, 250 to 350 parts of ganoderma lucidum spore powder, 50 to 150 parts of solanum lyratum, 250 to 350 parts of centipede, 200 to 300 parts of radix scutellariae, 250 to 350 parts of oldenlandia diffusa, 250 to 350 parts of herba andrographitis, 400 to 500 parts of phellinus igniarius, 250 to 350 parts of radix tetrastigme, 50 to 200 parts of Chinese mahonia and 100 to 250 parts of agkistrodon halys. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, removing blood stasis and phlegm, eliminating sores and removing stasis and is used for treating liver cancer and intestinal cancer.
Owner:TONGYITANG PHARM CO LTD

Composition, preparation, food and application for enhancing immunity

The present invention provides a composition, preparation method, food product, and application thereof, which are related to the field of food and health care technology. The composition comprises the following components: protamine, maca powder, a traditional Chinese medicine extract, raspberry powder, polysaccharide, and collagen; the traditional Chinese medicine extracts are American ginseng, wolfberry, and andrographis paniculata; the mass ratio of American ginseng, wolfberry, and andrographis paniculata is 2-6:2-4:2-4. The composition provided by the present invention, through the specific components, proportions, and preparation method, not only has the efficacy of significantly improving immunity and anti-aging ability, but also has a good taste.
Owner:HENGYU BIOPHARMACEUTICAL (SHANDONG) CO LTD +1

A thin layer chromatography method for identifying the medicinal properties of Hou Shuning tablets

The present invention belongs to the technical field of traditional Chinese medicine detection, and in particular to a thin layer chromatography identification method for the whole prescription of Hou Shuning tablets. The thin layer chromatography identification method for the whole prescription of Hou Shuning tablets provided by the present invention comprises the following steps: S1, preparation of Hou Shuning tablet test solution; S2, preparation of control medicinal material solutions of Hedyotis diffusa, Andrographis paniculata and Sesame; S3, using a polyamide thin layer plate, with anhydrous ethanol-acetic acid-water as a developing agent, spraying with aluminum chloride-ethanol solution for inspection, and performing thin layer chromatography identification. The present invention establishes an identification method for the three medicinal flavonoid components of Hou Shuning tablets, promotes the improvement of Hou Shuning tablets quality control, and can be used as a reference for the quality study of flavonoid components of single medicinal materials of Hedyotis diffusa, Andrographis paniculata and Sesame, filling the gap in the thin layer chromatography identification of flavonoids of Hedyotis diffusa, Andrographis paniculata and Sesame.
Owner:SINOPHARM GRP DEZHONG (FOSHAN) PHARM CO LTD

Traditional Chinese medicine compound suppository for treating endometritis of livestock and preparation method of traditional Chinese medicine compound suppository

The invention provides a traditional Chinese medicine compound suppository for treating endometritis of livestock and a preparation method of the traditional Chinese medicine compound suppository, and relates to the technical field of veterinary drugs. The traditional Chinese medicine compound suppository consists of povidone iodine, a traditional Chinese medicine composition and a slow-release high polymer material matrix carrier, wherein the traditional Chinese medicine composition is prepared from thirteen traditional Chinese medicine components including philippine flemingia root, common andrographis herb, zanthoxylum dissitum, Chinese angelica, suberect spatholobus stem, motherwort herb, baical skullcap root, honeysuckle flower, weeping forsythia capsule, white paeony root, nutgrass galingale rhizome, heartleaf houttuynia herb and swordlike atractylodes rhizome. Besides the matrix carrier, the traditional Chinese medicine compound suppository only contains povidone iodine and traditional Chinese medicine composition components, the content of the povidone iodine component is low, and side effects are reduced. The traditional Chinese medicine compound suppository is non-toxic, small in irritation to vaginal mucosa of livestock, high in effective rate of treating endometritis of the livestock and good in anti-inflammatory effect. In the preparation process of the traditional Chinese medicine compound suppository, no organic solvent is used, pollution to the environment is avoided, and the preparation process is simple, convenient and easy to implement and low in cost.
Owner:ZHOUKOU VOCATIONAL & TECHN COLLEGE

Pharmaceutical composition for synergistically inhibiting klebsiella pneumoniae and infectious pneumonia of klebsiella pneumoniae, preparation and application

The invention relates to the technical field of pharmaceutical compositions, in particular to a pharmaceutical composition for synergistically inhibiting klebsiella pneumoniae and infectious pneumonia of the klebsiella pneumoniae, a preparation and application, and the composition is prepared from the following components in parts by weight: 50-200 parts of berberine, 10-100 parts of andrographolide, 10-100 parts of manuka honey and 10-50 parts of polymyxin B. In-vitro antibacterial study is carried out on the berberine, the andrographolide, the manuka honey and the polymyxin B, and it is found that the andrographolide, the berberine and the manuka honey can all improve the antibacterial effect of the polymyxin B and all generate a synergistic effect when being combined for use; besides, the combination of the four medicines provided by the invention is used for treating a mouse suffering from Klebsiella pneumonia infectious severe pneumonia, the effect of the combination of the four medicines is obviously superior to that of a single medicine, and the effect of treating the Klebsiella pneumonia infectious severe pneumonia can be obviously improved after the medicine composition provided by the invention is compounded.
Owner:佳木斯市中心医院

Application of Danyankang preparation in preparation of medicine for treating non-alcoholic steatohepatitis (NASH)

The invention discloses application of a Danyankang preparation in preparation of a medicine for treating non-alcoholic steatohepatitis, the Danyankang preparation is prepared from eight traditional Chinese medicines including glechoma longituba, rumex madaio, saxifraga stolonifera, sabia parviflora, phoenix-tail fern, scutellaria baicalensis, golden cypress and andrographis paniculata according to a specific weight ratio, and the Danyankang preparation has the effects of clearing heat, promoting diuresis, detoxifying and dispersing blood stasis. The core pathogenesis of the NASH damp-heat accumulation syndrome is precisely matched. A single-arm and multi-center clinical research shows that the preparation can remarkably improve the main curative effect index liver / spleen CT ratio of NASH (damp-heat accumulation syndrome) patients, effectively relieve traditional Chinese medicine clinical symptoms (the total effective rate of traditional Chinese medicine syndromes is 94.44%) such as hypochondrium swelling pain, bitter taste, heavy body and drowsiness), and is good in safety and free of adverse reactions related to drugs. According to the invention, new indications for treating NASH (damp-heat accumulation syndrome) are expanded for Chinese patent medicines on the market, and a treatment choice which is definite in curative effect, safe and accessible is provided.
Owner:GUIZHOU BAILING GRP PARMACEUTIAL CO LTD

Andrographolide synthesis related p450 cytochrome enzymes and application thereof

The application discloses a group of andrographolide synthesis related P450 cytochrome enzymes and application thereof, and belongs to the field of bioengineering. On the basis of original sequences CYP71A8 and CYP71D10 from Andrographis Herba, the signal peptide sequence is truncated, and the heterologous expression of CYP7A8 and CYP71D10 after the signal peptide is successfully realized. In the application, the host is Saccharomyces cerevisiae CEN.PK2-1D, the ROX1 and GAL80 genes on the genome are knocked out, and the coding genes of GGPP synthase and CPS diterpene synthase are integrated at the ROX1 site; CYP71A8 and CYP71D10 and ApCPR are expressed freely, and the recombinant Saccharomyces cerevisiae is successfully constructed, the de novo synthesis of 3,15,19-Trihydroxy-8(17),13-ent-labdadiene-16-oic acid is realized, and the response value of the product peak reaches 1.9*106 compared with the blank, which is the only related report on the biosynthesis of 3,15,19-Trihydroxy-8(17),13-ent-labdadiene-16-oic acid at present. The strategy provides a necessary reference for analyzing the andrographolide biosynthesis pathway and synthesizing andrographolide and related derivatives by metabolic engineering.
Owner:JIANGNAN UNIV

Application of andrographolide in promoting growth of calves and relieving weaning stress based on microbial community regulation effect

The invention provides application of andrographolide in promoting calf growth and relieving weaning stress based on a microbial community regulation effect, and belongs to the technical field of animal feeding. The andrographolide (AG) can significantly improve the growth performance and the health level of the calves, relieve the weaning stress of the calves and improve the respiratory tract health of the calves by inhibiting inflammation and oxidative stress and systematically regulating and controlling microbial communities at multiple parts. Under the low-dosage feeding level, AG is more prone to optimizing rumen microflora, rumen is promoted to turn to an efficient propionic acid type fermentation mode, and sustainable benefits are achieved; and under a high dosage level, AG exerts a stronger anti-inflammatory and anti-oxidation effect to realize short-term benefit maximization. AG is added, so that the cross-site interaction between microbial communities in the digestive tract and the nasal cavity is enhanced, the colonization of various potential pathogens in the nasal cavity is remarkably inhibited, and the respiratory tract health of the calf is improved.
Owner:SOUTH CHINA AGRICULTURAL UNIVERSITY

An extract of a plant and its preparation method and application

The application provides a kind of plant extraction antiallergic agent and its preparation method and application, it is related to the cosmetic technical field.Plant extraction antiallergic agent includes component: andrographis extract, cactus extract, liquorice extract, ophiopogon extract and portulaca oleracea extract;Cactus is crushed, and cellulase and pectinase are added to carry out enzymolysis;Residue is extracted using 50-60% ethanol solution in volume concentration under the condition of 30-40 DEG C reduced pressure, and cactus extract is obtained;Ophiopogon is mixed with 20-40% ethanol in volume concentration, and microwave treatment is carried out under the condition of 500-800W, then reflux extraction is carried out, and ophiopogon extract is obtained;Liquorice is crushed, mixed with solvent choline chloride and 1,3-butanediol, and liquorice extract is extracted.The preparation method of plant extract is researched, 5 components are mutually coordinated, and the effect of anti-allergy, skin soothing and anti-inflammatory is good, and it is widely applied in the preparation of anti-allergic cosmetics or anti-allergic drugs.
Owner:BEIJING SANYOU HUILHI BIO-TECH CO LTD

Anti-allergy repair composition containing lindera aggregata and andrographis paniculata, and preparation method and application thereof

PendingCN120899598ACosmetic preparationsHair cosmeticsTRPV1 receptorAllergy
The invention provides an anti-allergy repairing composition containing lindera aggregata and andrographis paniculata as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The technical problem to be solved is to provide the cosmetic containing the lindera aggregata and the andrographis paniculata, which has repairing and anti-allergy effects and is simple and safe in components. The key points of the technical scheme are as follows: 1) a preparation method of a lindera aggregata extract and an andrographis paniculata extract; 2) a lindera aggregata extract and an andrographis paniculata extract in a specific ratio; and 3) application of the composition containing the lindera aggregata extract and the andrographis paniculata extract in anti-allergy repair cosmetics. The components are extracted from Chinese herbal medicines, and the components are simple, so that the traditional Chinese medicine composition is safer to use. Meanwhile, a good anti-allergy effect can be achieved by inhibiting TRPV1 receptor activation, HaCaT cells can be promoted to express FLG and LOR, and a remarkable repairing effect is achieved.
Owner:HANGZHOU HUIYUYE COSMETICS TECHNOLOGY CO LTD

Lake water quality purification floating island

The invention belongs to the technical field of water purification devices, and particularly relates to a lake water purification floating island. The method comprises the following steps: firstly, improving a floating island from the aspect of a matrix material, wherein the matrix material is prepared from the following components in parts by weight: 20-25 parts of straw with the length of 1-2mm, 10-15 parts of a filter material, 20-25 parts of activated sludge, 10-15 parts of andrographis paniculata powder and 5-10 parts of canna indica leaf powder; the survival rate of aquatic plants is increased, the pollution rate of weeds and miscellaneous algae is reduced, and a good water purification effect is achieved. The structure is improved, a floating bed is included, a filling bin is arranged on the floating bed, the movable chain is used for planting aquatic plants, and filler filled in the filling bin and the movable chain is a matrix material. The floating island structure is matched with the matrix material, and nutrients required by initial growth are supplemented to the aquatic plants through the filling bin.
Owner:INNER MONGOLIA AGRICULTURAL UNIVERSITY +1

Preparation method of traditional Chinese medicine feed additive for improving goose meat quality

The invention belongs to the technical field of breeding feed additive preparation, and particularly relates to a preparation method of a traditional Chinese medicine feed additive for improving goose meat quality, the preparation method comprises the following specific steps: selecting cordyceps flower, olive powder, Chinese yam, selfheal, dried mushroom, andrographis paniculata, lotus seed, grape seed, wild buckwheat rhizome, fingered citron, chicory and rose, and drying; cellulase, 1, 4-alpha-D-glucan maltohydrolase and a 0.1 mol / L acetic acid solution are prepared, the reagent purity needs to meet the feed additive grade standard, and the goose meat value is comprehensively improved from the two aspects of taste and quality through four synergistic mechanisms of nutrient enrichment, metabolism regulation, flavor optimization and meat structure improvement.
Owner:AGRICHINA HUAWEI BIOPHARMACEUTICAL HUBEI CO LTD +1

A traditional Chinese medicine composition for treating avian colibacillosis and a preparation method thereof

The application provides a traditional Chinese medicine composition for treating avian colibacillosis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations.The preparation method is as follows: 12-15 parts of Huangqin, 9-11 parts of Huanglian, 3.5-4.5 parts of Jinyinhua, 5-7 parts of Chuanxinlian and 5-7 parts of Pugongying are mixed, crushed, 8-10 times of the mass of an acidic ethanol solution is added, extracted, filtered, and a composite liquid one is obtained; 11-13 parts of Gegen, 10-12 parts of Baotouweng, 4-5 parts of Cebaiye, 6-7 parts of Wuhezi and 7-9 parts of Zixingujia are mixed, crushed, 8-10 times of the mass of an ethanol aqueous solution is added, extracted, filtered, and a composite liquid two is obtained; the composite liquid one and the composite liquid two are respectively vacuum rotary evaporated to a relative density of 1.09-1.13, mixed, and spray dried, and the traditional Chinese medicine composition is obtained.The traditional Chinese medicine composition prepared by the application has a fast effect speed and a remarkable curative effect for treating avian colibacillosis of chicks.
Owner:HENAN BRIGHT SPOT PHARM CO LTD

Detection method of traditional Chinese medicine preparation for liver and gallbladder damp-heat accumulation

The invention discloses a detection method of a traditional Chinese medicine preparation for liver and gallbladder damp-heat accumulation, the traditional Chinese medicine preparation is prepared from 200 parts by weight of glechoma longituba, 200 parts by weight of dock root, 200 parts by weight of saxifraga stolonifera, 200 parts by weight of sabia parviflora, 200 parts by weight of phoenix-tail fern, 200 parts by weight of scutellaria baicalensis, 200 parts by weight of golden cypress and 200 parts by weight of andrographis paniculata. The detection method is characterized by comprising the steps of thin-layer identification and content determination of components, wherein thin-layer chromatography identification is carried out on glechoma longituba, rumex madaio and andrographis paniculata, and content determination is carried out by using a high performance liquid chromatography to determine the content of effective components of glechoma longituba, rumex madaio and scutellaria baicalensis in the preparation. The detection method is simple, stable and reliable, and effectively ensures the product quality.
Owner:GUIZHOU BAILING GRP PARMACEUTIAL CO LTD