17 results about "Terminalia" patented technology

The present invention provides a method of isolating arjunetin from the bark of Terminalia arjuna. The invention provides a simplified, cost-effective method and scalable method for isolation of arjunetin from the Terminalia bark. The present invention encompasses an ethanolic extract of arjunetin that comprises arjunetin with 95% purity. The ethanolic extract of arjunetin is obtained from solvent extraction without using column chromatography. Arjunetin has various therapeutic applications, anti-diabetic, anti-inflammatory, anti-cancer, and anti-viral drugs.

The invention provides a traditional Chinese medicine external application composition for treating gastroparesis after brain injury and a preparation method thereof. The traditional Chinese medicine external application composition is prepared from the following components: rhizoma acori graminei, paederia scandens, radix polygoni multiflori preparata, aloe, gastrodia elata, semen aesculi, phyllanthus emblica, stephania tetrandra, turmeric, radix fici simplicissimae, fructus piperis longi, swertia pseudochinensis, rhizoma nardostachyos, lily, ginkgo leaves and cynanchum paniculatum. Dual mechanisms of neuroprotection and gastrointestinal motility regulation are creatively fused, central nervous injury can be improved through components such as rhizoma acori graminei and radix polygoni multiflori preparata, gastrointestinal hormone secretion and slow-wave pace-making functions can be synchronously regulated through components such as paederia scandens and turmeric, and compared with a conventional single-target treatment means, the traditional Chinese medicine composition is more suitable for a complex pathological mechanism of gastric paralysis after brain injury. Meanwhile, the preparation process is simple, the cost is low, external application avoids aggravation of gastrointestinal burdens, common western medicine side effects such as arrhythmia are avoided, clinical operation is convenient, patient tolerance is good, the gastric emptying recovery time is remarkably shortened, and the risk of complications such as aspiration pneumonia is reduced.

The invention relates to an active pharmaceutical ingredient for repairing oral mucosa and a preparation method of the active pharmaceutical ingredient, and belongs to the technical field of biological medicine, and the active pharmaceutical ingredient comprises an amanita aurantiaca mycelium active peptide-myrobalan polyphenol composite entrapment substance, a dendrobium nobile callus extract, sorbitol, menthol, a gel matrix and the like. The amanita aurantiaca mycelium active peptide-myrobalan polyphenol composite entrapment substance is obtained by entrapment of a compound of amanita aurantiaca mycelium active peptide and myrobalan polyphenol through a sodium alginate-dopamine grafted copolymer; the amanita aurantiaca mycelium active peptide is obtained by performing common enzymolysis on the mycelium of amanita aurantiaca through bromelain and bacillus subtilis protease. The dendrobium nobile callus extract is obtained by inducing slices of dendrobium nobile seedling leaves with 2, 4-D and 6-BA, extracting and purifying. The gel matrix is prepared from modified konjac glucomannan and carboxymethyl chitosan. All the components form an anti-inflammatory, proliferative and remodeled closed-loop repair system, and the anti-degradation stability and the adhesion long-term effect are improved.

The invention belongs to the technical field of bioengineering, and particularly relates to myrobalan fruit nano-vesicles, a preparation method and application of the myrobalan fruit nano-vesicles in skin aging resisting products. The preparation method comprises the following steps: firstly, carrying out enzymolysis on a myrobalan fruit raw material by adopting a compound enzyme preparation containing feruloyl esterase, and adding sodium alginate and a calcium chloride solution into enzymatic hydrolysate after enzymolysis to carry out precipitation treatment on nano-vesicles; and finally, treating the precipitate by adopting a sodium carbonate or sodium bicarbonate solution, fully stirring, centrifuging, and collecting the supernatant, thereby obtaining the purified product of the myrobalan fruit nano-vesicle. The preparation method of the myrobalan fruit nano-vesicle is efficient and low in cost, the content of miRNA in the obtained nano-vesicle is high, animal experiments show that the nano-vesicle can reduce the content of IL-6 inflammatory factors in experimental animal skin tissue and reduce collagen loss caused by ultraviolet rays, and the nano-vesicle has remarkable anti-aging and light aging relieving effects and can be used for preparing the nano-vesicle. The method can be applied to functional skin care products.

The application discloses a method for constructing a Vietnamese terminalia regenerative system, and comprises the following steps: Vietnamese terminalia stem segment test materials are obtained by grafting seedling saplings with superior branches, semi-lignified stem segments with axillary buds are used as explants, and after disinfection, the explants are inoculated into an induction culture medium to induce axillary buds, then the induced axillary buds are subjected to micro-branch cutting to carry out proliferation and rooting culture, and a large number of Vietnamese terminalia regenerative plants can be obtained. The method has the advantages of high propagation efficiency, high phenotype consistency, good genetic stability and the like, greatly shortens the production cycle of Vietnamese terminalia seedlings, reduces the variation risk of the seedlings, and provides high-quality seedlings for ecological afforestation and landscaping.

The present application relates to a kind of active pharmaceutical ingredients of repairing oral mucosa and preparation method thereof, belong to biological medicine technical field, and drug includes orange cover gonggao mycelium active peptide- Terminalia polyphenol composite package, dendrobium nobile callus extract, sorbitol, menthol, gel matrix etc.Orange cover gonggao mycelium active peptide- Terminalia polyphenol composite package is the complex of orange cover gonggao mycelium active peptide and Terminalia polyphenol by sodium alginate-dopamine graft copolymer package;Orange cover gonggao mycelium active peptide is the mycelium of orange cover gonggao mushroom by bromelain and bacillus subtilis protease common enzymolysis obtains.Golden lace dendrobium callus extract is the section of golden lace dendrobium seedling leaf by 2,4-D and 6-BA induction, extraction, purification and obtains.Gel matrix is prepared by modified konjac glucomannan and carboxymethyl chitosan.Each component forms anti-inflammatory, proliferation and remodeling closed-loop repair system, and improves the stability of anti-degradation and adheres long-acting.

The present application relates to a kind of compound traditional Chinese medicine preparation for treating colorectal cancer, it is made by Devil's needle grass, chicken eye grass, Prunus, Terminalia according to certain weight distribution ratio, its preparation method is that the above raw material is added 60% ethanol 10 times, heated reflux extraction 3 times, every 2 hours, extract is combined, recovers ethanol, concentrates and evaporates dry, vacuum drying, different dosage forms corresponding appropriate amount of auxiliary materials are added, and conventional preparation method is used to be made into tablet, capsule, granule, pill and the like.The traditional Chinese medicine compound preparation described in the present application shows that the antitumor effect experiment result has the effect of inhibiting colorectal cancer tumor cell growth.

The invention discloses a traditional Chinese medicine composition for treating wound ulcer and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The prescription is composed of 5-15 parts of slender gouania root, 5-10 parts of maggot, 0.01-0.5 part of venenum bufonis, 5-10 parts of American cockroach, 5-15 parts of abelmoschus manihot, 3-9 parts of rheum officinale, 1-5 parts of safflower and 5-15 parts of fructus chebulae, the dosage form is external ointment, powder, oil, liquid preparation and the like, the traditional Chinese medicine composition is remarkable in curative effect, the cure rate can reach 85% or above after 2 months of treatment, the average healing time is shortened by 40 days or above, safety is high, and the traditional Chinese medicine composition is suitable for clinical application. The traditional Chinese medicine composition is suitable for chronic intractable wound ulcer such as diabetic foot ulcer, and the problem of poor treatment effect in the prior art is solved.

The application belongs to the technical field of bioengineering, and particularly relates to a Terminalia chebula Retz. fruit nano vesicle, a preparation method thereof and application of the nano vesicle in anti-skin aging products. In the application, a composite enzyme preparation containing ferulic acid esterase is used to perform enzymolysis on Terminalia chebula Retz. fruit raw materials, sodium alginate and a calcium chloride solution are added to the enzymolysis liquid after the enzymolysis, and the nano vesicle is subjected to precipitation treatment; finally, a sodium carbonate or sodium bicarbonate solution is used to treat the precipitate, the mixture is fully stirred, centrifuged, and the supernatant is collected to obtain a purified product of the Terminalia chebula Retz. fruit nano vesicle. The preparation method of the Terminalia chebula Retz. fruit nano vesicle provided by the application is efficient and low in cost, the nano vesicle obtained has a high miRNA content, animal experiments show that the nano vesicle can reduce the content of IL-6 inflammatory factors in the skin tissue of experimental animals, reduce the loss of collagen caused by ultraviolet rays, has significant anti-aging and light-aging alleviating effects, and can be applied to functional skin care products.

The object of the present invention is to provide a novel composition for inhibiting the nuclear translocation of NFATc1 and NFATc2 for anti-allergic purposes. [Solution] The NFATc1 and NFATc2 nuclear translocation inhibitory composition according to the present invention contains an aqueous extract of Terminalia bellirica fruit as an active ingredient. The term "composition" as used herein includes preparations such as liquid foods, supplements and food additives, food and beverages (excluding plants and animals themselves), food and beverage compositions (including processed food and beverages), pharmaceutical compositions, and other substances that can be ingested by animals (including humans).

The invention provides a preparation method of terminalia parvifolia wood pulp fibers, a moisture absorption core body and agricultural greenhouse moisture absorption equipment. The preparation method comprises the following steps: step 1, collecting terminalia parvifolia plants, and crushing the collected terminalia parvifolia plants into wood chips; 2, the wood chips are placed under saturated steam, pressure maintaining is carried out for set time, pressure relief is carried out, and explosion is completed; step 3, diluting the obtained blasting product with water according to a set solid-to-liquid ratio, adjusting the pH value to a range suitable for cellulase action, adding a catalytic effective amount of cellulase, stirring at a set temperature, and carrying out enzymolysis; 4, grinding the pulp subjected to enzymolysis to obtain wood pulp fibers; step 5, extracting and compounding antibacterial components: extracting the antibacterial active components from a terminalia hancei plant, and mixing and dipping the antibacterial active components with the wet fibers to enable the antibacterial components to be adsorbed on the surfaces of the fibers; step 6, freeze drying: performing pre-freezing and sublimation drying to obtain the Terminalia hance wood pulp fibers. The method has the beneficial effects that the maintenance time and the material replacement cost are greatly reduced, and the long-period dehumidification requirement of the greenhouse is met.

The application provides a traditional Chinese medicine composition and application thereof in preparation of anti-fatigue health care wine, and relates to the technical fields of traditional Chinese medicine pharmacy and health care. The traditional Chinese medicine composition is prepared from medicinal and edible traditional Chinese medicinal materials, and is composed of Cistanche, Acanthopanax, Radix Asparagi, Phyllanthus emblica, Typha angustifolia, Terminalia, Chrysanthemum, Rubus corchorifolius, Canavalia, and Citrus medica, and has the effects of tonifying kidney and spleen, benefiting qi and nourishing yin, and clearing and tonifying. The traditional Chinese medicine composition and the health care wine prepared from the traditional Chinese medicine composition have excellent anti-fatigue effects, can significantly prolong the exhaustive swimming time of mice under load, significantly reduce the urea nitrogen content in plasma of mice after exercise, significantly increase the liver glycogen content of mice, significantly increase the blood lactic acid clearance rate of mice after exercise, and have a significant effect of relieving physical fatigue. The traditional Chinese medicine composition is expected to be developed into an anti-fatigue drug or health care product.

To provide an oral composition having excellent glucagon-like peptide-1 secretion promoting action and appetite suppressing action.SOLUTION: The glucagon-like peptide-1 secretion-promoting composition contains Terminalia beryllia. The appetite suppressing composition contains Terminalia beryllia.SELECTED DRAWING: None

The invention provides a pharmaceutical composition, a preparation and application thereof. The pharmaceutical composition comprises the following components in percentage by weight: 5%-85% of an extract of seabuckthorn seeds, 5%-85% of an extract of hedyotis diffusa, 5%-85% of an extract of watermelon seeds and 5%-85% of an extract of phyllanthus emblica. Wherein% refers to the mass percentage content of each extract in the pharmaceutical composition. The pharmaceutical composition disclosed by the invention contains natural components with medicinal characteristics, can reduce blood pressure, cholesterol and blood sugar, and is stable in long-term curative effect; at the same time, these natural ingredients do not cause side effects, dependency risks, possibilities of drug resistance development, complex interactions, long-term health risks, environmental influences, compliance challenges, symptom masking, and ethical issues.

The invention particularly discloses a traditional Chinese medicine composition for treating mild depression, a medicament and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 20 parts of karst medicine terminalia fruit pulp, 15 to 20 parts of medicine terminalia fruit pulp, 15 to 20 parts of emblic leafflower fruit peel, 15 to 20 parts of fructus chebulae immaturus, 5 to 10 parts of coreopsis tinctoria root, 7 to 10 parts of Japanese polypody rhizome, 7 to 10 parts of pogonatherum crinitum, 7 to 10 parts of lavender and 40 to 600 parts of refined honey. According to the traditional Chinese medicine composition for treating mild depression, the medicament and the preparation method of the traditional Chinese medicine composition, the honey cream has a more remarkable effect on depression treatment, particularly has a remarkable effect on animal behavioral change, and is easy for modern industrial production.

The object of the present invention is to provide a novel interleukin-9 production inhibitory composition for anti-allergic purposes. [Solution] The interleukin-9 production inhibitory composition according to the present invention contains an aqueous extract of Terminalia bellirica fruit as an active ingredient. The term "composition" as used herein includes preparations such as liquid foods, supplements and food additives, food and beverages (excluding plants and animals themselves), food and beverage compositions (including processed food and beverages), pharmaceutical compositions, and other substances that can be ingested by animals (including humans).

The invention discloses a preparation method of a cross-linked hair-growing microneedle, and belongs to the technical field of biological medicine, and the preparation method comprises the following steps: S1, adding crushed fructus terminaliae billericae, fructus chebulae and emblic leafflower fruit into ethanol, uniformly mixing, performing ice-bath crushing, extracting filtrate, evaporating and concentrating into paste, and freeze-drying; s2, carrying out hydrothermal carbonization and purification treatment on the fructus terminaliae billericae / fructus chebulae / fructus phyllanthi extract; s3, adding the fructus terminaliae billericae / fructus chebulae / emblic leafflower fruit extract, the fructus terminaliae billericae / fructus chebulae / emblic leafflower fruit carbon dot powder and carboxymethyl chitosan into a mixed solvent, and performing cross-linking reaction to obtain the cross-linking type hair growing microneedle. With the self-crosslinking function of Tibetan medicine natural extract and macromolecular polymer carboxymethyl chitosan, the crosslinked material can promote hair growth by adjusting the ecological niche of hair follicle stem cells, adjusting hair growth related pathways and the like while improving the hardness of the microneedle; the technical bottlenecks of an existing hair growth microneedle material in the aspects of single function, mechanical reliability and safety are solved.