135 results about "American cockroach" patented technology

The invention relates to uses of Bombay canary and its alcohol extract in preparing medicine for treatment of inflammation, specifically, for treating cervical erosion, ulcerative colitis, fig wart after operation, said invention belongs to medicine field.

The invention discloses an artificial breeding method of bombay canary. The eggs separation, indoor breeding way is used, and a ventilated, light penetrated chips breeding rack with transversal multi-gaps and vertical multi-layers is used; the temperature keeps at 28-30degree and the humidity keeps at the range of 65-75%; the illuminance keeps at the range of 10-15LUX, wherein the natural illumination is main and the lamplight illumination is subsidiary; the illumination time is 10-14hour. The bombay canary is fed using cooked food and killed in batch one month after the peak time of the adult copulation and eggs-laying and the temperature rises to 38-40degree during killing process and the killing time is about 30minute, therefore the bombay canarys die and are used as medicine after post processing. The artificial breeding method of bombay canary can artificially adjust and control all the index on the base of the natural growth rhythm of bombay canary, thus the medical component is increased and the growth cycle is reduced and the artificial breeding method is suitable for large-scale industrialization breeding.

The invention provides a method for detecting an active ingredient (3R) -3-methyl-7-hydroxymethyl-8-hydroxyl-3,4-dihydroisocoumarin-6-O-beta-D-glucopyranoside, namely KFX-4 in an American cockroach extract. In the method, high performance liquid chromatography (HPLC) is adopted, octadecylsilane chemically bonded silica is taken as a filler; methanol or acetonitrile-water (0-50:100-50 V / V) is taken as a mobile phase of which the flow speed is between 0.2 and 2.0 ml / min; the detection wavelength is one or more wavelengths of between 210 and 400 nanometers; a diode array detector is adopted; the sample size is between 5 and 50 mu l; theoretical plate number is not less than 4,000 when calculated according to a KFX-4 peak; the separation degree with a neighboring impurity peak is more than 1.5; chromatographic analysis is performed; and KFX-4 content is calculated by a peak area external standard method. An effective quality control method is provided for Chinese medicinal Kangfuxin solution and the method has a large practical value in the aspect of improving product quality and medicament safety.

The invention discloses an American cockroach medicinal composition for curing ulcers or ulcerative inflammation. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and montmorillonite powder. The weight part ratio of the American cockroach extract to the montmorillonite powder is equal to 0.8-1.2:0.5-6. A preparation method of the American cockroach medicinal composition for curing the ulcers or the ulcerative inflammation comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and has obvious effects of effectively curing diseases such as oral ulcers, recurrent aphthous ulcers, oral lichen planus, oral mucosal injury (behcet disease, herpes simplex, leukoplakia, discoid lupus erythematosus, hand-foot-and-mouth disease, scalds, chemotherapy, radiotherapy and the like) caused by various reasons, reflux esophagitis, eophageal ucers, radiation esophagitis, ulcerative colitis, radiation proctitis, and diarrhea, and hematochezia with mucosal injury, and the like.

The invention discloses a toothpaste containing an American cockroach extract and a preparation method thereof. According to the invention, the American cockroach extract prepared under specific process conditions is added into the toothpaste as an active constituent having an effect of adjuvant therapy, and special biological activity, such as alanine, in American cockroach is utmostly retained in the extract, so the toothpaste not only has the effect of synchronous nursing of the oral cavity, teeth and gums, but also has remarkable therapeutic effects on oral ulcer; therefore, the toothpaste has an immense application value.

The invention provides compound cockroach glucosides A to C and a drug composition thereof and their application in preparation of pharmaceuticals and health-care products for treating ulcers and burns and scalds. Ulcers and burns are fairly common, and American cockroaches clinically used for various ulcers and burns have a good effect. Three dihydrogen isocoumarin glucosides are separated and identified and are named as the cockroach glucosides A, B and C, and all the cockroach glucosides can promote dermal fibroblast collagen secretion of human and improve the treatment effect on the collagen secretion lack diseases, such as all kinds of ulcers, burns and scalds.

The invention discloses a method for cultivating medicinal American cockroaches. The method comprises the steps of preincubation and feeding, and particularly comprises the steps that chosen worm eggs and heat insulation materials are mixed evenly and then laid in an incubation tray, incubation is conducted for 20-25 days under the condition that the temperature is 28-32 DEG C and the humidity is 75%-85%, a cultivation bracket is moved, incubation is continuously conducted for 25-35 days under the conditions that the temperature is 25-30 DEG C and the humidity is 65%-75%, then the tray is removed, the American cockroaches are fed by fodder, the fodder is made of corn, wheat, bean pulp, fish, shrimps and additives, feeding is conducted for five to seven months, and pest control is conducted during feeding. According to the method, artificial temperature control, humidity control cultivation, worm egg separation, artificial incubation and fixed feed formulas are used, cooked food is used for feeding, the yield of the medicinal American cockroaches is improved, the cultivation process and the environment can better improve the incubation rate of the eggs of the American cockroaches and the survival rate of the larvas of American cockroaches, the medicinal components are obviously improved, and the quality of medicine is good. According to a dry product, the free amino acid content is higher than 6.0 mg / g, the combination amino acid content is higher than 5.0 mg / g, and the inosine content is 50-100 mg / 100g.

The invention provides a low-temperature preparation method for an American cockroach extract. The method comprises the following steps: (1) taking American cockroaches or degreased American cockroaches, adding a solvent, extracting at low temperatures and combining an extraction liquid; and (2) recovering the solvent from the extraction liquid at a reduced pressure and concentrating to obtain the American cockroach extract. According to the novel process for extracting the American cockroach extract provided by the invention, the active ingredients of the American cockroaches are effectively retained, and the pharmacodynamics activity of the obtained extract is superior to the product which is prepared in the prior art, so that the method has a relatively good market application prospect.

The invention relates to an American cockroach-honey refined flavor cream and a preparation method thereof. The American cockroach-honey refined flavor cream consists of the following compositions in percentage by weight: 55 to 60 percent of American cockroaches, 35 to 40 percent of honey and 0 to 10 percent of auxiliary materials, wherein the auxiliary materials are pollen pini, sweet osmanthus, pale butterflybush flower, rose or Saruma henryi. The preparation process comprises the following steps: using 70 DEG C hot water to soak and kill live insects of the American cockroaches; baking and drying and sterilizing polypide as soon as possible, and crushing the polypide into thick paste; and mixing and stirring the treated American cockroaches, the auxiliary materials which are sterilized and crushed into powder, and the honey which is subjected to hot smelt in a water bath, in a mixer to obtain the finished product. The prepared product not only maintains the special health-care, nourishing and beautifying efficacies of the American cockroaches, but also adds the nutrition of the honey and the auxiliary materials, and forms high-grade health food with special flavor. The processing technique is simple, convenient and easy.

The invention provides an American cockroach water-soluble protein as well as an extraction process and application thereof. According to the technical scheme, the process is realized through the following steps: a, degreasing; b, performing crude protein extraction; c, dialyzing; and d, drying, thereby obtaining the product. The protein concentration of the American cockroach water-soluble protein obtained by the extraction process disclosed by the invention reaches 8121.531 [mu]g / ml, the concentration of an American cockroach extracting solution obtained through a salt extraction method is 4913.55 [mu]g / ml, and the advantages of the extraction process disclosed by the invention can be obviously seen through comparison. The American cockroach water-soluble protein disclosed by the invention can be applied to foods or medicines or feed additives.

The invention discloses an American cockroach medicinal composition for curing gastritis and peptic ulcers. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract, white peony root, bletilla, radix pseudo-ginseng, liquoric root, Indian buead, rhizoma corydalis, cuttlebone and belladonna extract. The weight part ratio of the American cockroach extract to the white peony root to the bletilla to the radix pseudo-ginseng to the liquoric root to the Indian buead to the rhizoma corydalis to the cuttlebone to the belladonna extract is equal to 0.8-1. 2g :1-10g:1-10g:0.5-6g:0.25-6g:0.25-10g:0.5-6g:0.83-6g:5-60mg. A preparation method of the American cockroach medicinal composition for curing the gastritis and the peptic ulcers comprises the following steps of: preparing the American cockroach extract, weighting, decocting, and mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and effectively improves curative effects on the gastritis and the peptic ulcers.

The invention discloses an American cockroach medicinal composition for curing oral ulcers. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and rabdosia rubescens. The weight part ratio of the American cockroach extract to the rabdosia rubescens is equal to 0.8-1. 2: 5-40. A preparation method of the American cockroach medicinal composition for curing the oral ulcers comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and effectively improves curative effects on oral ulcer diseases.

The present invention provides new application of drug residues after alcohol extraction of American cockroach in preparation of anti hepatic injury drugs. According to the studies, the drug residues after alcohol extraction of American cockroach are effective on the treatment of hepatic injury, especially alcohol hepatic injury, and improve the utilization rate of the resources of medicinal materials.

The invention provides water gel woundplast containing American cockroach active ingredients. The water gel woundplast comprises a water gel layer and a high-elasticity base body layer, wherein the water gel layer achieves a healing effect and is in contact with the skin. The water gel woundplast is characterized in that the water gel layer is prepared from the following ingredients in parts by mass: 1 to 3 parts of American cockroach extracts, 1 to 2 parts of bletilla extracts, 1 to 3 parts of chitosan hydrochloride, 1 to 4 parts of polyvinylpyrrolidone K30, 0.05 to 0.1 part of HPMC10W, 0.5 to 1.5 parts of PVA-17880, 1 to 3 parts of glycerol and 20 to 30 parts of pure water. In the contact process of the water gel woundplast with the skin, the water gel layer has the effects of inhibitingbacteria, diminishing swelling, relieving pain and prompting skin healing through the American cockroach extracts and the bletilla extracts; meanwhile, through the chitosan hydrochloride loaded withantibacterial materials with high biocompatibility, the antibacterial and bleeding stopping effects are further improved; the healing time is shortened; the medicine dwell time is prolonged; the wounded surface can better absorb the medicine; the skin tissue restoration is accelerated; the wound healing and regeneration rate is improved; meanwhile, the good waterproof effect and skin-friendly comfort are realized.

The invention relates to a method for preparing cockroach insecticide tablets by Sichuan pepper essential oil. The method comprises the following steps: crushing Sichuan pepper by utilizing a crusher according to a ratio of 10ml to 15ml of a Sichuan pepper essential oil extract liquid, 400ml of absolute ethyl alcohol, 100ml of tween 80 and 100g to 150g of agar, adding distilled water to soak the crushed Sichuan pepper, and extracting the Sichuan pepper essential oil extract liquid for standby use in a vapor distilling method; uniformly mixing the absolute ethyl alcohol and tween 80, and then adding the Sichuan pepper essential oil extract liquid to obtain the Sichuan pepper essential oil insecticide slow-release preparation; adding the agar into the distilled water, heating and dissolving the agar, cooling the agar, and slowly adding the essential oil insecticide slow-release agent prepared in the step 2 into the agar solution, heating and stirring the mixed solution, uniformly mixing the mixed solution, and slowly pouring the mixed solution into a hollow cylindrical forming mold to prepare a cylindrical round bar; cutting the cylindrical round bar into tablets; and applying the glue on one side of each tablet to prepare the cockroach insecticide tablet. The method is simple in preparation process, low in cost and diversified in applicable environments, and the repellent rate of the prepared cockroach insecticide tablet for American cockroach and German cockroach can reach 88 to 100 percent.

The invention discloses Wingless signal channel genes related with the regeneration of severed limbs of American cockroach and applications of dsRNA of the same. The genes are Wg, Arr, and Dsh. The nucleotide sequence of Wg is represented by SEQ ID No.1; the nucleotide sequence of Arr is represented by SEQ ID No.2; and the nucleotide sequence of Dsh is represented by SEQ ID No.3. Through design, dsRNA of the genes related with the regeneration of severed limbs of American cockroach is targetedly silenced so as to control American cockroach.

The invention belongs to the field of traditional Chinese medicine health, and particularly relates to traditional Chinese medicine instant tea with an anticancer health function and a preparation method of the traditional Chinese medicine instant tea. The traditional Chinese medicine instant tea is prepared from the following components in parts by weight: 2-10 parts of anticancer drug composition extract, 15-30 parts of fruit concentrated juice and 20-40 parts of black tea extract, wherein the anticancer drug composition consists of 8-15 parts of black fungus powder, 10-20 parts of aloe powder, 5-10 parts of grape seed powder, 10-20 parts of citrus peel powder and 8-15 parts of American cockroach powder. The preparation method of the traditional Chinese medicine instant tea comprises the following steps: respectively filtering the anticancer drug composition extract and the black tea extract by using an ultrafiltration membrane with a molecular weight of 5000-7000; carrying out reverse osmosis and concentration until the content of solid matter is 40-50%; uniformly mixing the two components obtained by the concentration with the fruit concentrated juice; carrying out freeze drying to obtain the traditional Chinese medicine instant tea. The traditional Chinese medicine instant tea not only has a favorable anticancer effect, but also has a better taste; the tea beverage obtained by brewing the traditional Chinese medicine instant tea does not have a strong traditional Chinese medicine taste, has a fruit taste and is easily accepted by people.

The invention discloses a colonic tablet containing an effective part of American cockroach and a preparation method thereof. The colonic tablet comprises American cockroach freeze-dried powder, a filler, a disintegrating agent, a wetting agent and a lubricating agent, wherein a mass ratio of the American cockroach freeze-dried powder to filler is 1:1.5; the amount of the lubricating agent is 0.3% of the total amount of the American cockroach freeze-dried powder and filler; and the amount of the disintegrating agent is 3% of the total amount of the American cockroach freeze-dried powder and filler. According to the colonic tablet containing the effective part of American cockroach disclosed by the invention, due to a colon coating technology, the drug effect is maintained, and absorption is promoted, so that the drug bioavailability is improved, bad odor of the drug is masked, the stability of the preparation is guaranteed, and reduction of the treatment effect and adverse reaction caused by quality differences of the preparations are reduced. According to the preparation form of the tablet, the colonic tablet is small in administration dose, rapid in absorption, stable in quality, convenient to carry, easy to preserve and particularly suitable for industrial production.

The invention discloses an incubation method of an American cockroach. The incubation method includes the following steps: step 1, taking braided fabric and an egg support for incubation and disinfecting the braided fabric and the egg support for backup; step 2, placing the braided fabric on an incubation plate, placing an American cockroach ootheca on the incubation plate, and covering the egg bracket on the ootheca; and step 3, placing the incubation plate in an incubation box or an incubation chamber for incubation with the temperature of the incubation box or the incubation chamber of 27-33 DEG C and relative humidity of the incubation box or the incubation chamber of 70-85%, and meanwhile, spraying water on the egg support until the incubation is finished, wherein the water spraying amount is 300-2200ml / m*m.d. The incubation method of the American cockroach is high in incubation rate, easy to operate and low in cost.

The invention discloses an American cockroach medicinal composition for curing gastritis and peptic ulcers. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and gypsum. The weight part ratio of the American cockroach extract to the gypsum is equal to 0.8-1. 2g : 2.5-40g. A preparation method of the American cockroach medicinal composition for curing the gastritis and the peptic ulcers comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and effectively improves curative effects on the gastritis and the peptic ulcers.

The invention discloses a medicine composite for treating burn and scald, which consists of the mixure of American cockroach extractive and active constituents of pberetima and flies. The proportioning, by weight percent, is the American cockroach extractive to the pberetima to the flies equals to 100 to 10-100 to 10-100. The preparation method of the medicine composite for treating burn and scald comprises the following steps: extracting the American cockroach extractive, extracting of pberetima and the the active constituents of the flies, and mixing the extractive and the active constituents to prepare the medicine. The invention gives full play to the action of the American cockroach extractive, effectively improves the efficacy of treating burn and scald, has the advantages of simple preparation method, convenient use, short heating time, little toxic and side effect and is a new medicine worth of generalization.

The invention provides an American cockroach extract-containing anti-inflammatory and antiulcer toothpaste. The toothpaste is produced from, by mass, 42.0-53.0% of hydrated silica, 20.0-38.0% of an excipient, 1.0-2.0% of glue, 0-1.5% of aspartame, 2.0-4.0% of a foaming agent, 0-0.3% of an essence, 0.02% of an antiseptic, 0-0.2% of trichlorohydroxydiphenyl ether, 0-0.05% of tranexamic acid, 0.5-6.0% of American cockroach extract, 0.1-1.5% of wild chrysanthemum flower extract, and the balance of deionized water, and the sum of mass fractions of all above components is 100%. The American cockroach extract is added to make the toothpaste have very good inflammation prevention, bacterium prevention and tissue repairing promotion effects, and the wild chrysanthemum flower extract which is also added in the invention has heat clearing, internal heat repelling, bacterial preventing, inflammation preventing, oxidation preventing and mutation preventing effects.

The invention discloses American cockroach freeze-dried powder based pre-essence which is prepared from the following raw materials: American cockroach freeze-dried powder, fructus anrederae cordifoliae extract, common perillae seed extract, caulis dendrobii officinale extract, Chinese yam extract, fresh dried rehmannia root extract, kudzu vine root extract, ganoderma lucidum extract, chamomile flower extract, flower-de-luce, sweet osmanthus flower, butterflybush flower, rose, honeysuckle flower, glycerol, alcohol and deionized water. The invention further discloses a preparation method for American cockroach freeze-dried powder based pre-essence. The American cockroach freeze-dried powder based pre-essence can maintain genes from source, can promote and improve synthesis of proteins, improves skin microcirculation, improves the skin dull-yellow problem and the pachulosis problem, has the effects of shrinking enlarged pores, homogenizing skin color, concealering, whitening, resisting inflammatory, wrinkles and ageing, screening sunlight, and the like. After the American cockroach freeze-dried powder based pre-essence is used, skin changes to be tender and smooth in touch, skin color is improved, skin quality is remarkably improved; and moreover, raw materials are basically pure natural traditional Chinese medicines, have excellent corrosion resistance, do not need to add any preservative, do not harm skin, and are high in safety coefficient.

The invention relates to a quality detection method of a rehabilitation new preparation which is made from barbaric cockroach (American cockroach) drug material and the extract thereof. The quality detection method of the rehabilitation new preparation is constructed through a plurality of experiments. In said method, octadecylsilane chemically bonded silica is used as filling agent; diammonium phosphate is used as mobile phase; uracil is added with to be dissolved as reference solution; high performance liquid chromatography is used for detecting the sample solution of the rehabilitation new preparation to obtain the content determining method of the uracil in the rehabilitation new preparation. The method is relatively simple, is provided good precision, reproducibility and reliability and can be applied to the quality control of the rehabilitation new preparation.

The invention discloses an American cockroach medicinal composition for curing gastritis and peptic ulcers. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and omeprazole. The weight part ratio of the American cockroach extract to the omeprazole is equal to 0.8-1.2g: 0.33-80mg. A preparation method of the American cockroach medicinal composition for curing the gastritis and the peptic ulcers comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and effectively improves curative effects on the gastritis and the peptic ulcers. The American cockroach medicinal composition has no responses such as headache, diarrhea, astriction, stomachache, sicchasia, emesis skin eruption, dizziness, somnolence and insomnia and the like, and basically does not increase transaminase or bilirubin.

The invention provides an anti-caries toothpaste containing an American cockroach extract. The toothpaste is characterized by being prepared from the following raw materials in percentage by weight: 40.0 to 55.0% of abrasive agent, 18.0 to 33.0% of excipient, 1.0 to 2.0% of glue, 0 to 5.0% of xylitol, 2.0 to 4.0% of foaming agent, 0.02% of sodium benzoate, 0 to 0.3% of essence, 0 to 0.76% of sodium monofluorophosphate, 0 to 5.0% of hydroxyl apatite, 1.0% of Chinese gall extract, 0.5 to 3.0% of American cockroach extract, and the balance being deionized water, wherein the total percentage of all components is 100%. The toothpaste contains the American cockroach extract and Chinese gall extract, and thus has a very good effect on preventing and curing caries, reducing tooth tartar, relieving pain, and killing bacteria.

The invention discloses an American cockroach medicinal composition for curing oral ulcers. The medicinal composition is mainly prepared from an active ingredient mixture prepared by mixing an American cockroach extract and metronidazole. The weight part ratio of the American cockroach extract to the metronidazole is equal to 0.8-1. 2: 0.1-0.8. A preparation method of the American cockroach medicinal composition for curing the oral ulcers comprises the following steps of: preparing the American cockroach extract, mixing active ingredients, and preparing medicaments. The medicinal composition has simple preparation method, fully exerts effects of the American cockroach extract, and effectively improves curative effects on oral ulcer diseases.

The invention discloses an ultrahigh-pressure extraction method for american cockroach. The ultrahigh-pressure extraction method for american cockroach comprises the following steps: (1) taking american cockroach powder, adding water or ethanol solution with a concentration of 50-90%, and extracting for 1-5 times and for 5-20 minutes every time under an ultrahigh pressure to obtain an extract, wherein the pressure for the ultrahigh-pressure extraction is 100-800MPa, and the temperature is 20-80 DEG C; (2) filtering the extract in the step (1) to obtain a supernatant, and concentrating the supernatant to obtain a concentrate; (3) refrigerating the concentrate in the step (2) for 24-48h, removing upper-layer oil, centrifuging to obtain a supernatant, concentrating, drying and crushing. The ultrahigh-pressure extraction method disclosed by the invention is capable of effectively extracting the effective ingredients of american cockroach, high in yield, simple and convenient to operate, and good in application prospect.

The invention provides a special feed for an American cockroach nymph. The feed is prepared from the following raw materials by weight: 40 to 50 parts of corn, 10 to 20 parts of wheat, 8 to 15 parts of soybean meal, 6 to 10 parts of fish meal, 4 to 10 parts of silkworm chrysalis, 3 to 6 parts of dried yeast, 3 to 7 parts of rice bran, 3 to 5 parts of pea, 1 to 3 parts of white sugar, 1 to 2 parts of bone meal and 0.1 to 0.5 part of salt. The invention further provides a preparation method and an application method for the special feed. The feed provided by the invention has reasonably coordinated nutrients and is clean and hygienic to manufacture; and after feeding of the feed, the American cockroach nymph has substantially enhanced disease resistance and an increased survival rate, and growth and development of the American cockroach nymph are promoted.

The invention provides an application of American cockroach lipid in tumor prevention. Researches reveal that the American cockroach lipid can be used for effectively inhibiting the growth of tumor cells of a breast cancer, a rectal cancer, a liver cancer and the like, is good in antineoplastic activity and provides a new choice for clinical medication.