74 results about "Vaseline" patented technology

The invention belongs to the technical field of pressure sore treatment, and discloses an experimental test method for treating stress injury based on danshen emodin, which comprises the following specific steps: step 1, preparing experimental materials, selecting a healthy SD (Sprague Dawley) rat, and preparing a clean and sterile magnet and a shaver; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 1 part of isoflurane, 1 part of iodophor, 1 part of Vaseline, 1 part of Rhapontigenin and 1 part of resveratrol. The method comprises the following steps: modeling a stress injury model for an SD (Sprague Dawley) rat so as to simulate a stress injury disease, then respectively smearing three medicines, i.e., Danjie emodin, resveratrol and vaseline, tracking the healing condition of a stress injury wound, and finally performing ELISA (Enzyme-Linked Immunosorbent Assay) and Hamp; according to the present invention, the detection analysis is performed through the dyeing E, and the results show that the rheum emodin has good treatment effect on the stress injury, can reduce the expression of the proinflammatory factor, can promote the wound healing, has characteristics of environmental protection and low cost, and provides the new research direction for the treatment of the stress injury.

The invention provides a compound nystatin ointment and a preparation method thereof, and relates to the technical field of medicine preparation, the compound nystatin ointment comprises active ingredients of nystatin, neomycin sulfate, triamcinolone acetonide and permethrin, and the formula comprises liquid paraffin, white vaseline, wool fat, hexadecanol, PEG-30 dipolyhydroxystearate and glyceryl monoisostearate. According to the compound nystatin ointment preparation prescription process disclosed by the invention, the phenomenon of ointment matrix layering in the use process of commercially available products is mainly solved. According to a pharmaceutical research test, the stability of the compound nystatin ointment is superior to that of a commercially available original development agent, the ointment body character and the stability of active ingredients can be kept under the conditions of high temperature, high humidity, low temperature, freeze thawing and illumination, the maximum single impurity content and the total impurity content in the product are not obviously increased, and the quality is controllable. And meanwhile, an in-vitro transdermal test (IVPT) accidentally finds that the retention amount of related active ingredients is higher than that of the original development agent, and the drug effect is obviously improved. Through clinical test research, the compound nystatin ointment disclosed by the invention can be used for effectively treating external otitis caused by bacteria sensitive to neomycin, fungi sensitive to nystatin and ear mites sensitive to permethrin of dogs and cats.

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.

The invention relates to the technical field of oral medical materials, and particularly provides a macromolecular denture adhesive and a preparation method thereof.The denture adhesive is prepared from, by mass, 40-45 parts of oil phase matrix; 50 to 55 parts of an adhesive; 1 to 2.5 parts of a reinforcing agent; 0.1 to 1 part of a bacteriostatic agent; 0.1 to 1 part of an auxiliary material; wherein the reinforcing agent comprises calcium carbonate; the oil phase matrix comprises white oil and vaseline, and the mass ratio of the white oil to the vaseline is (0.8-1): 1. The eggshell powder is used as a natural filling forming viscosity enhancer, so that the bonding strength of the false tooth adhesive can be remarkably improved, and the high requirement of a patient on false tooth stability is met.

The utility model discloses a portable eyeshade capable of preventing exposed keratitis, which comprises a main body unit and a treatment unit, the main body unit comprises an eyeshade body, an elastic band is fixed on the eyeshade body, two through grooves are arranged in the eyeshade body, and the eyeshade body is provided with an adjusting component for adjusting whether shading is carried out or not. The eyeshade comprises two vaseline moisturizing dressings fixed on an eyeshade body, and sterile hydrophilic dressings are fixed on one sides of the vaseline moisturizing dressings. The medicine bag is placed in the storage cavities in the vaseline moisturizing dressing and the sterile hydrophilic dressing, then the vaseline moisturizing dressing is turned over so that the vaseline moisturizing dressing can block the through groove, the medicine bag can treat the eye, the vaseline moisturizing dressing is fixed by embedding the positioning column into the cylinder, namely, the medicine bag is fixed, and the medicine bag can be used for treating the eye. After the shifting rod moves upwards to enable the positioning column to move out of the cylinder body, the vaseline moisturizing dressing can be turned over from the through groove, and the eyes of the patient can be observed through the through groove.

This invention relates to the field of peppermint balm technology, specifically disclosing a peppermint balm with moisturizing and soothing functions and its preparation method, comprising the following raw materials in parts by weight: 40-45 parts white petrolatum, 15-20 parts houttuynia cordata extract doped with nano-silica, 10-15 parts paraffin, 10-15 parts menthol, 5-10 parts trehalose, 2-5 parts hydroxyethyl cellulose, 25-30 parts glycerin, and 2-5 parts Tween-80. The peppermint balm of this invention uses white petrolatum combined with paraffin, and is further blended and formulated with menthol, trehalose, hydroxyethyl cellulose, glycerin, Tween-80, and a modifier. Through the synergistic effect of the attapulgite modifier and the houttuynia cordata extract doped with nano-silica, the prepared peppermint balm achieves a coordinated improvement in moisturizing efficacy, soothing properties for skin redness and swelling from insect bites, and long-lasting antibacterial properties, thus improving the product's efficiency.

This invention relates to the field of baby bath gel technology, specifically to a moisturizing baby bath gel and its preparation method. It comprises, by weight percentage: 10.0%~30.0% of a complex amphoteric surfactant system, 5.0%~15.0% of an amino acid surfactant, 2.0%~10.0% of a nano-moisturizing oil system containing petrolatum nano-oils, 0.5%~2.0% of a conditioning agent, 1.0%~5.0% of plant extracts, and the balance being an aqueous matrix. The complex amphoteric system is composed of a low-impurity coconut oil-based amphoteric diethylene glycol and sodium lauroyl amphoteric acetate synthesized in a two-step temperature-controlled process. This invention abandons strongly irritating anionic surfactants and high-dose polymeric thickeners, utilizing the synergistic construction of a dense worm-like micelle network by two amphoteric surfactants. This not only achieves long-term stable suspension of petrolatum nano-oils in an extremely mild system, but also targets and deposits oils during emulsification during bathing, achieving a combined cleansing and conditioning experience with an extremely gentle, tear-free safety.

Compositions and methods for the treatment of inflammatory skin diseases. The compositions include a pharmaceutically effective amount of polyhexamethylene biguanide (PHMB), polyaminopropyl biguanide (PAPB), and / or chlorhexidine (CHG) in a petrolatum carrier.

The application provides a white-borneol apricot kernel face mask liquid and a preparation method and application thereof, and relates to the technical field of cosmetics. The preparation raw materials of the white-borneol apricot kernel face mask liquid provided by the application include white petrolatum 5-20 parts, mono-diglyceride 1-10 parts, methyl p-hydroxybenzoate 0.01-8 parts, glycerol 1-10 parts, butanediol 0.05-10 parts, Tween-80 0.05-12 parts and compound extraction liquid 10-30 parts in terms of weight percentage. The white-borneol apricot kernel face mask liquid provided by the application has good moisturizing effect, is cold and heat resistant, has good stability and meets the microbial detection standard of cosmetics.

This invention discloses a lutein-infused massage and care eye ointment containing precious Chinese medicinal herbs, free of eight major allergens, and suitable for all ages. Each tube contains 10 grams. The formula uses lutein as its core ingredient, combined with artificial musk, bear bile powder, pearl powder, ginseng, and Ganoderma lucidum, along with eye-protecting ingredients such as wolfberry, chrysanthemum, cassia seed, and buddleja flower. It is supplemented with sodium hyaluronate and vitamin B6, using medical-grade hypoallergenic petrolatum as a base. The ointment is strictly free of eight major allergens, making it safe and gentle, suitable for people aged 3 to 100. This invention features a simple process, can be industrially produced, and can effectively relieve eye fatigue, dry eyes, itchy eyes, bloodshot eyes, dark circles, eye bags, wrinkles, photophobia, and tearing in the wind, among other sub-healthy eye problems. It has extremely high market application and health care value.

The invention relates to an ointment-containing adult diaper specially developed for adult patients suffering from urinary and fecal incontinence, comprising an ointment layer (1) containing zinc oxide, petrolatum, lanolin, aloe vera, panthenol, and vegetable oils (capric / caprylic triglyceride, stearyl alcohol, sweet almond oil, olive oil, calendula officinalis flower extract, hamamelis virginiana (witch hazel) extract), which protects the skin from irritation, moisturizes it, and provides a healing effect, and further comprising absorbent, liquid distribution, and breathable outer layers that protect skin health.

To provide a nasal application agent for suppressing allergic reactions of the human body caused by water-soluble allergens.SOLUTION: A first step I comprises mixing and stirring Vaseline with a vegetable oil, and a first step II comprises mixing and stirring a sugar alcohol such as mannitol with a thickener such as finely powdered cellulose. In a second step after the first steps I and II, a gel I comprising the stirred Vaseline and vegetable oil such as olive oil, and a gel II comprising the stirred sugar alcohol and thickener are mixed and stirred together. The resulting gel has both hydrophilic and hydrophobic properties, and the allergen-blocking gel for nasal application has an effective molar osmotic pressure higher than that of body fluids, i.e., 330 mOsm / L or more. Furthermore, by adding a herb oil from the Lamiaceae family, the allergen-blocking gel can also provide "refreshing nasal sensation and, by the herb oil from the Lamiaceae family, alleviated inflammation of the nasal mucosa".SELECTED DRAWING: Figure 1

Compositions and methods for the treatment of inflammatory skin diseases. The compositions include a pharmaceutically effective amount of polyhexamethylene biguanide (PHMB), polyaminopropyl biguanide (PAPB), and / or chlorhexidine (CHG) in a petrolatum carrier.

The invention discloses a skin cell nucleus nutritional agent containing traditional Chinese medicine components and capable of improving ichthyosis and a preparation method, and relates to the technical field of preparation of skin cell nucleus nutritional agents. Comprising the following raw materials: modified vitamin A propionate, a traditional Chinese medicine extract, modified hydrogenated lecithin, squalane, beewax, stearyl alcohol, vaseline, glycerin, sodium hyaluronate, beta-glucan, propylene glycol, potassium cetyl phosphate, a preservative, allantoin, deionized water, triethanolamine and a lipid solvent. According to the invention, the modified tretinoin propionate is added, and the modified tretinoin propionate is subjected to double-grafting modification through glycyrrhetinic acid-hyaluronic acid oligosaccharide and is gently combined with a basal cell tretinoin receptor in a targeted manner, so that excessive proliferation of basal cells can be inhibited, and normal differentiation of keratinocytes can be promoted; wherein the glycyrrhetinic acid component can resist inflammation, relieve and reduce self-irritation, and the hyaluronic acid oligosaccharide can improve targeting and transdermal efficiency, avoid light / oxygen degradation and provide a core regulation effect for restoring the 28-day metabolic cycle of basal cells.

The invention belongs to the technical field of medical protection articles, and particularly relates to a foot wound nursing medicine used after corn removal, a preparation method and a foot wound nursing paste.The foot wound nursing medicine is prepared from, by weight, 66.67-72.73% of vaseline and 27.27-33.33% of liquid paraffin, the average molecular weight of the vaseline is 226-450, the average molecular weight of the liquid paraffin is 226-450, and the average molecular weight of the liquid paraffin is 226-450. The average molecular weight of the liquid paraffin is 254-422. The foot wound nursing medicine provided by the invention can form a physical barrier to isolate a wound from the external environment, so that harmful substances such as bacteria and dust can be prevented from entering the wound, the risk of infection is reduced, direct friction between the wound and external clothes, gauze and the like can be avoided, and pain and secondary injury caused by friction are reduced. Besides, the foot wound nursing medicine formed after the interaction of the liquid paraffin and the vaseline can form a lipid membrane to contact the wound, and can provide a suitable wet healing environment for the wound and promote the wound healing after being smeared on the debrided wound.

The invention provides a Baiqing essential oil composition for treating blood deficiency and wind dryness syndrome of chronic eczema, and belongs to the field of biological medicine. The white tea essential oil composition comprises sweet wormwood essential oil and white tea essential oil, the mass ratio of the artemisia apiacea essential oil to the white tea essential oil is (1-5): 1. The Baiqing essential oil emulsifiable paste is guided by the theory of traditional Chinese medicine and follows the theory and principle of prescription compatibility, the artemisia apiacea is used as the monarch for clearing heat and expelling evil, the white tea is used as the minister for eliminating dampness and treating sores, and the effects of resisting inflammation and relieving itching are jointly achieved. Vaseline is used as a matrix, oily substances are used for nourishing and moistening the skin and enhancing the efficacy, and the traditional Chinese medicine composition has an excellent effect on treating the blood deficiency and wind dryness syndrome of chronic eczema, especially the blood deficiency and wind dryness syndrome of mild and moderate chronic eczema. Compared with vaseline or an artemisia apiacea / white tea essential oil mixture which is independently used, the white tea and green tea essential oil emulsifiable paste has a better treatment effect and plays a synergistic interaction role. The invention provides a new clinical basis for subsequent traditional Chinese medicine treatment of chronic eczema (blood deficiency and wind dryness syndrome).

This application relates to the field of pharmaceutical technology, and in particular to a topical ointment formulation and its preparation method. The formulation uses Sonicate as the active ingredient, combined with petrolatum, liquid paraffin, a solubilizing and penetration-enhancing system, and emulsifiers as excipients, to form an O / W type cream, an oil-based or water-soluble ointment. The preparation process employs a low-temperature dosing method at 40°C to ensure drug activity and inhibit crystallization. This application achieves high-concentration retention in local skin tissue through topical administration, significantly reducing radiation damage scores and pathological damage, while resulting in extremely low systemic plasma exposure, avoiding the systemic toxicity of oral administration, and providing a safe and efficient means for the clinical prevention and treatment of radiation-induced skin damage.

The invention relates to the technical field of oral care, in particular to high-molecular composite false tooth safety paste and a preparation method thereof. The denture safety paste specifically comprises the following components in parts by weight: 10-20 parts of white oil; 20 to 40 parts of Vaseline; 20 to 40 parts of CMC (carboxy methyl cellulose); 20 to 40 parts of PVM-MA (Polyvinyl M-Methacrylate); 0.1 to 1 part of silicon dioxide; 0.1-1 part of 95% ethanol; 0.05 to 1 part of methylparaben; 0.05 to 1 part of menthol; 0.05 to 1 part of peppermint oil; 0.001 to 0.01 part of azo jade red; and 8-12 parts of hydrophobic modified chitosan. The denture fixing paste provided by the invention has high bonding strength, can tolerate high stability requirements under the scenes of excessive chewing, frequent water drinking and the like, can realize long-acting stability for 12-18 hours, and is easy to pick after being used.

The invention relates to anti-freezing and anti-cracking hand cream which comprises a water-phase component, an oil-phase component and a functional additive, the water-phase component accounts for 60-70% by weight, the oil-phase component accounts for 25-35% by weight, and the functional additive accounts for 3-8% by weight; wherein the water phase component is prepared from 30 to 40 percent of pure water, 8 to 15 percent of glycerol, 3 to 8 percent of urea, 2 to 4 percent of hyaluronic acid, 1 to 3 percent of maltitol and 0.2 to 0.35 percent of sodium glucoheptonate; and the oil phase component comprises 8-15% of vaseline, 5-10% of mineral oil, 3-8% of shea butter and 2-5% of beewax. The invention further relates to a preparation process of the anti-freezing and anti-cracking hand cream. Five industry pain points of'heavy, mud rubbing, stimulation, short-term effect and instability 'are converted into quantifiable engineering indexes one by one, the magnitude order advantage is obtained in four dimensions of absorption speed, washing resistance, repair rate and low-temperature stability, meanwhile, the process is kept simple, and the cost is controllable.

The invention provides a calcipotriol ointment and a preparation method thereof.The ointment preparation is prepared from, by weight, 0.005 part to 0.01 part of calcipotriol, 5 parts to 10 parts of tussilagone, 8 parts to 23 parts of glycerin monostearate, 20 parts to 50 parts of white vaseline, 10 parts to 20 parts of paraffin, 20 parts to 40 parts of liquid paraffin, 15 parts to 45 parts of polyethylene glycol 400 and 8 parts to 12 parts of propylene carbonate.The formula of the calcipotriol ointment is improved; a certain proportion of tussilagone is added into the prescription, and the preparation method is improved, so that the defect that calcipotriol is easy to decompose is overcome, the problem of unstable calcipotriol content is solved, the stability of the calcipotriol ointment is improved, the content of related substances of the calcipotriol ointment is reduced, and the calcipotriol ointment has a synergistic effect in the aspect of treating psoriasis.

The invention provides an ointment for treating skin and soft tissue ulceration and a preparation method thereof. The ointment comprises the following components in parts by weight: 5-20 parts of red mercury, 5-15 parts of borneol, 10-20 parts of myrrh, 5-10 parts of talcum powder and 6-11 parts of vaseline. All the components of the ointment supplement each other to achieve a synergistic effect, the medicine components directly reach the focus through skin orifices, toxin extraction and tissue regeneration promotion, detumescence and ulceration inhibition, bleeding stopping and suppuration are achieved from inside to outside, bacteriostasis and inflammation diminishing are achieved, and wound healing is rapidly promoted.

This invention belongs to the field of pharmaceutical formulation technology and relates to a clobetasol propionate ointment and its preparation process. The ointment comprises clobetasol propionate, an emulsifier, a solubilizer, a stabilizer, a secondary stabilizer, and an ointment base. The emulsifier is Tween-80, the solubilizer is propylene glycol, the stabilizer is povidone K15 or povidone K25, the secondary stabilizer is potassium chloride, and the ointment base is white petrolatum. This invention, by adding a stabilizer and a secondary stabilizer and screening their types, prepares a clobetasol propionate ointment that exhibits low impurity content and good stability during long-term storage. Furthermore, the preparation process is simple and easy to operate, facilitating industrial production.

The invention discloses plant extract face cream for removing wrinkles, fading spots, whitening and moisturizing and a preparation method thereof, and belongs to the technical field of cosmetics. The face cream is composed of an agent A (oil phase) and an agent B (water phase) according to the weight ratio of 3: 7, the agent A contains vaseline, beeswax and the like, and the agent B contains a plant extract concentrated solution, glycerin and a pine pollen suspension. The plant extract is prepared by a process combining ultrasonic treatment with 5% white rice vinegar, liquid nitrogen freezing and grinding, water extraction and ethanol reflux, and then the face cream is formed by a gradient homogeneous emulsification process. Through cooperation of multiple plant components and an innovative process, the retention rate and transdermal absorption efficiency of active components are improved, and the skin care product has the effects of removing wrinkles, fading spots, whitening and moisturizing, is high in stability and good in safety, and meets the requirements of natural skin care products.

1. The name of the design product: packing bottle (O'Pevon Vaseline egg white fragrance hand cream). 2. The use of the design product: packing bottle for packing cosmetics. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo best indicating the design points: perspective view.

The application discloses a traditional Chinese medicine external treatment moxa plaster and a preparation method thereof, which comprises the following components in parts by weight: 15-35 parts of folium artemisiae argyi essential oil, 8-15 parts of frankincense, 10-30 parts of tabernaemontana divaricata, 0-5 parts of an antioxidant, 0-5 parts of a preservative, 0-4 parts of a transdermal enhancer, 20-40 parts of vaseline, 15-35 parts of beeswax and 1-5 parts of vegetable oil. The components of the application complement each other and promote each other. When the plaster contacts the skin, the plaster can rapidly generate a mild and lasting heat and comfort feeling due to the introduction of the tabernaemontana divaricata, and the plaster has no irritation to the skin. The heat production temperature of the plaster is maintained at 39-43 DEG C, and the heat feeling can last for 85-95 minutes. The effective components of the folium artemisiae argyi essential oil can rapidly penetrate the skin and play the efficacy under the heat effect generated by the tabernaemontana divaricata, and the problems of inconvenience, safety hazards and irritation in the prior art are solved.

The invention discloses a preparation process and application of a lipid hydrocolloid silver sulfate acetate fiber dressing, and the preparation process comprises the following steps: sequentially adding thermoplastic rubber, liquid paraffin, tackifying resin, an antioxidant and a plasticizer into a kneading machine, stirring and mixing, then adding sodium carboxymethyl cellulose and silver sulfate, continuously stirring to uniformly mix, and thus obtaining the lipid hydrocolloid silver sulfate acetate fiber dressing. The preparation method comprises the following steps: preparing a hollow reticular cellulose acetate fiber spunlace non-woven fabric, adding medical vaseline, simethicone, liquid paraffin and citric acid to obtain a mixture, uniformly coating the hollow reticular cellulose acetate fiber spunlace non-woven fabric with the obtained mixture by adopting an extruder, cutting the hollow reticular cellulose acetate fiber spunlace non-woven fabric into a required shape, packaging, and carrying out radiation crosslinking to obtain the lipid hydrocolloid silver sulfate cellulose acetate fiber dressing. When the prepared dressing is used, a healing microenvironment with certain humidity and an antibacterial effect is provided, and the dressing is not adhered to the surface of a wound and peripheral skin, so that the dressing is free of pain and bleeding when being replaced, is particularly soft and easy to curl, and has relatively good compliance to the wound which is difficult to fix, and the antibacterial property of the dressing is further improved.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a local external cream composition for treating psoriasis. The topical external cream composition for treating psoriasis is prepared from deaminated tyrosine, azone and a matrix, wherein the matrix is prepared from liquid paraffin, sorbitol, an emulsifying agent, tween-80, white vaseline, beewax, glycerin monostearate, solid paraffin and the like according to a specific weight percentage. By optimizing a prescription and a process, the cream composition which is good in stability, high in transdermal absorption efficiency and capable of effectively delivering DAT to a skin focus is prepared, psoriasis-like skin lesion is effectively improved, inflammation and epidermal hyperplasia are relieved, and the cream composition is good in safety. A brand-new, effective and safe external medicine selection and application are provided for the field of psoriasis treatment by taking the deaminated tyrosine as an active component.

Compositions and methods for the treatment of inflammatory skin diseases. The compositions include a pharmaceutically effective amount of polyhexamethylene biguanide (PHMB), polyaminopropyl biguanide (PAPB), and / or chlorhexidine (CHG) in a petrolatum carrier.

The invention discloses a hydrocortisone butyrate cream and a preparation method thereof. Each gram of the hydrocortisone butyrate cream comprises the following components: 1 mg of hydrocortisone butyrate, 100-120 mg of an oil phase solid, 100-150 mg of white vaseline, 40-60 mg of light liquid paraffin, 30-40 mg of an emulsifier, 5-20 mg of salicylic acid, 10-40 mg of lecithin, 50-80 mg of a humectant, 1-2 mg of anhydrous sodium citrate, and the balance of water. On the basis of the existing prescription, the salicylic acid and the lecithin are added into the formula, and the dosages of the salicylic acid, the lecithin and other auxiliary materials are controlled, so that the hydrocortisone butyrate cream which is small in generation amount of degraded impurities and relatively good in stability is obtained.

The application belongs to the technical field of medicines and the field of ophthalmic preparations, and provides a stable erythromycin ointment composition without preservatives and a preparation method thereof. Through pre-wetting dispersion of erythromycin and liquid paraffin, construction of a white vaseline-liquid paraffin heat-treated oil matrix, low-moisture control, final mixing and redispersion, and nitrogen headspace replacement design, the dispersion state, content uniformity and headspace oxygen level of erythromycin particles are cooperatively controlled, the dispersion stability and chemical stability are improved, the problem that intensive dispersion and stable protection and mild processing and clean production control cannot be considered at the same time is solved, and the stable erythromycin ointment composition without preservatives is suitable for the production of ophthalmic semi-solid preparations without preservatives.