25results about "Hydrocarbon active ingredients" patented technology

The present invention provides a composition that possesses antioxidant activity while having high bioavailability. [Solution] The present invention provides a composition containing 1 to 15% by weight of prolycopene, and a method of using the composition, such as to prevent or treat a condition related to oxidative stress.

The present invention relates to a kit of nutrient blend compositions for young individuals, in particular children aged between 0 and 66 months, each one of the compositions having age-specific ingredients. The kit of nutrient blend compositions is specifically aimed at promoting myelination of targeted brain regions, in particular the social brain, of children at specific ages and stages of brain development.

Novel fragrant and flavorful Cannabis plant products with defined chemistry customized to provide a desired, consistent and stable Entourage of Interest (EOI) and processes for making and using the same are provided.

Provided is a composition such as a cosmetic composition. This composition contains a ceramide NH in which the length of an acyl chain (acyl chain length) is C18.

The present invention relates to cannabinoid-based formulations, and more particularly to methods for preparing cannabinoid-based formulations, the formulations themselves, and their use in therapy. The present invention particularly relates to cannabidiol (CBD)-based formulations, their manufacture, and their use for the treatment of pain, inflammation, autoimmune diseases, neurological disorders, neoplasms, nausea, hypertension, hypertrophic cardiomyopathy, or fibrosis.

This application discloses a squalene / calcium phosphotungsten oleogel, its preparation method, and its applications, relating to the field of biomedical technology. The squalene / calcium phosphotungsten oleogel is composed of squalene and calcium phosphotungsten nanowires; by mass percentage, the calcium phosphotungsten nanowire content is 2-5%, and the squalene content is 95-98%. The squalene / calcium phosphotungsten oleogel exerts anti-inflammatory and antioxidant effects by scavenging excess ROS, and can restore cell membrane fluidity, weaken mechanosensitive YAP pathway activation, and synergistically promote photoaging repair and scarless healing through multiple pathways. This comprehensive regulatory strategy provides a new solution for skin damage repair.

This invention discloses a herbal compound shampoo composition for darkening, strengthening, relieving itching, removing dandruff, and nourishing the scalp, belonging to the field of daily chemical product technology. Addressing the shortcomings of existing herbal shampoos, such as unreasonable formulation, insufficient extraction of effective ingredients, poor resistance to hard water, and strong irritation, this invention uses 16 kinds of natural dried medicinal herbs as the core, following the principles of traditional Chinese medicine, divided into a 12-herb decoction group and a 4-herb addition group. Extraction is achieved through a specific process of decoction for 1 hour, followed by boiling for 5 minutes and steeping for 1 hour. It is combined with a mild excipient system including alkyl glycoside-0810 and sodium fatty alcohol polyoxyethylene ether sulfate, with optional addition of 0.1%–1.0% polyquaternium-10. All formulations correspond to a 20 kg finished product feed. This invention's product has multiple effects including darkening hair, strengthening hair, relieving itching, removing dandruff, and nourishing the scalp. It retains sufficient effective ingredients, is gentle and non-irritating, has strong resistance to hard water, a clear and stable texture, and a 0% adverse reaction rate. It is suitable for all types of scalp, especially for long-term use by those with sensitive scalps, hair loss, dandruff, and premature graying of hair.

The application relates to a preparation method and application of a ginsenoside-loaded triple-assembled Pickering emulsion, and belongs to the biomedical technology field. In order to solve the problems that the Pickering emulsion constructed by natural active ingredients in the prior art has insufficient mechanical strength of an interface film, is easy to break and lose stability, has passive release behavior, lacks controllability and environmental responsiveness, and is difficult to realize precise release, a ginsenoside-loaded triple-assembled Pickering emulsion is provided. Through a three-step cascade strategy of "molecule-interface-function", a stable "metal-phenol coordination network" interface layer is constructed on the surface of oil droplets, the physical and chemical stability of the emulsion is fundamentally improved, a Pickering emulsion which is all-natural, highly stable and has a pH response intelligent release function is successfully constructed, and the triple-assembled Pickering emulsion has significant advantages in stability, controllable release and function integration, and provides a feasible technical strategy for a response type delivery system design based on natural products.

This invention discloses a Trichosanthes kirilowii, Allium macrostemon, and Pinellia ternata decoction with the effects of promoting yang, dispersing stagnation, resolving phlegm, and relieving chest congestion, and its preparation method. The preparation method includes: taking 10-17 parts of Trichosanthes kirilowii, 9-13 parts of Allium macrostemon, 11-14 parts of modified Pinellia ternata, 1300-1500 parts of rice wine, and 8-15 parts of an anti-inflammatory agent, mixing them, heating to a boil, maintaining a gentle boil for 1.5-2.0 hours, filtering, centrifuging, and concentrating the filtrate under reduced pressure at low temperature to a relative density of 1.15-1.20 to obtain the decoction. The anti-inflammatory agent includes 5-9 parts of lycopene, 7-11 parts of Arisaema cum Bile, 5-9 parts of Ophiopogon japonicus, 6-11 parts of Cirsium japonicum, 8-14 parts of Lysimachia christinae, 6-10 parts of Prunus armeniaca, 5-7 parts of Cinnamomum cassia, and 4-9 parts of Phyllanthus urinaria. The modified Pinellia ternata, processed by alcohol extraction and fermentation extraction, has a high content of organic acids and total alkaloids and a significant antitussive and expectorant effect. This invention, through reasonable raw material formulation and preparation process, enables the prepared decoction to have good effects of promoting yang, dispersing stagnation, eliminating phlegm, and relieving chest congestion.

A method for preparing stable liquid emulsion forms of plant extract is provided. A plant extract having a bitter flavor is mixed with diluent oil as an oil mixture and heat is applied to the oil mixture. An emulsifying agent is dispersed in water as an emulsifying solution. The oil mixture is mixed with the emulsifying solution. The mixed oil mixture and emulsifying solution is homogenized as a liquid form of the plant extract. Gluconic acid is added to the liquid form of the plant extract. The bitter flavor of the plant extract is disguised by adding a bitter blocker to the liquid form of the plant extract.

The present invention relates to compositions comprising: (a) a carotenoid selected from the group consisting of octahydrolycopene, hexahydrolycopene, zeta carotene, or any combination thereof; and (b) a ceramide, said compositions having a synergistic effect in inhibiting or reducing collagen loss, and methods of use thereof.

The present invention relates to a composition comprising at least one psychedelic non-phosphorylated tryptamine, preferably derived from psychedelic psilocybin mushrooms, more preferably derived from psychedelic psilocybin mushrooms belonging to the Psilocybe genus, at least one antioxidant, wherein the antioxidant is at least one carotenoid, and at least one supplement selected from an amino acid, a vitamin, theobromine, caffeine, resveratrol, gamma aminobutyric acid and combinations thereof. The invention relates also to the pharmaceutical uses of the composition of the invention.

This invention discloses the preparation and application of a hydrophobic compound high-encapsulation protein carrier, belonging to the field of bionanomaterials and food functional factor delivery technology. This invention provides a hydrophobic lumen-modified ferritin mutant rXHF, obtained by mutating polar residues at positions 68, 76, 141, and 148 on the lumen surface of human heavy chain ferritin rHuHF to tryptophan. Using this mutant as a carrier, lycopene is compounded with lycopene at a molar ratio of 1:200 to prepare the lycopene nanodelivery system rXHF-LYC. This system has a lycopene encapsulation efficiency of 17.8% and a DPPH clearance rate of 30%. Through transferrin receptor-mediated endocytosis, it crosses the blood-brain barrier, delivering lycopene to the hippocampus, inhibiting oxidative stress and neuroinflammation, restoring cholinergic function, and improving age-related cognitive impairment. This invention provides a new carrier for brain-targeted delivery of hydrophobic functional factors and offers a new strategy for the intervention of age-related neurodegenerative diseases.

This invention provides a transdermal follicular delivery system for active ingredients based on a protein carrier. The system comprises a composite structure of a small molecule active ingredient, a bioactive protein, and a polymer shell, with a size of 40-150 nm and a polymer shell thickness of 10-70 nm. The zeta potential of this protein carrier-based transdermal follicular delivery system is positively charged. The small molecule active ingredient is loaded within the bioactive protein, and the polymer shell coats the bioactive protein to form a protein nanogel. Both the small molecule active ingredient and the bioactive protein have beneficial effects on hair follicles. When this transdermal follicular delivery system is applied to the surface of a hair follicle or skin, the functional small molecules are delivered transdermally along with the nanogel to the interior of the hair follicle and surrounding tissues, where they are released in a controlled manner, thus effectively exerting their effects.

The present invention provides compositions and pharmaceutical compositions of GPR84 agonists and GPR120 agonists for us in the treatment of obesity and overweight. The invention provides methods of treatment accordingly as well as a kit for use in the treatment of obesity and overweight.

This invention relates to compositions and methods for invasive and non-invasive procedural skincare. In particular, it relates to topical compositions for promoting skin repair, anhydrous topical compositions, methods for preparing a skin bed prior to dermatological treatment, and methods for promoting skin repair after dermatological treatment. More generally, this invention relates to skin care treatments, and more specifically to compositions and methods for promoting skin health, skin regeneration, skin repair, skin bed preparation, and enhanced wound healing.

A method for efficiently encapsulating lycopene using soybean lipoprotein belongs to the field of food processing and functional ingredient encapsulation technology. The preparation method includes: extracting soybean lipoprotein from soybean raw materials; pretreating the obtained protein using ultrasound-assisted pH shifting technology; mixing the protein solution with anionic polysaccharides; preparing a complex through a thermally induced Maillard reaction; using the complex solution as the aqueous phase; and subjecting it to high-speed shearing and ultrasonic treatment with an oil phase containing dissolved lycopene to obtain a lycopene-loaded Pickering emulsion. This invention significantly improves the stability of Pickering emulsions by constructing modified protein-anionic polysaccharide composite emulsion particles, achieving efficient encapsulation and protection of lycopene, thus solving the problems of easy degradation, poor water solubility, and low bioavailability of lycopene.

The present invention relates to a modified-release solid oral pharmaceutical composition, which is in the form of an enteric-coated capsule, wherein said capsule comprises cannabidiol (CBD), tetrahydrocannabinol (THC) and an emulsifier, and wherein the capsule optionally further comprises one or more cannabis terpenes. The solid oral pharmaceutical composition provided herein has a particularly advantageous modified release profile as well as an improved oral bioavailability as compared to conventional formulations of CBD and THC.

The present invention relates to a new oily composition based on liquid alkanes for preventing and / or treating pediculosis, in particular pediculosis of the head in humans or on animal fur.

Provided herein are treatments for cancers, such as endometrial cancers. Compositions, methods, and kits are described herein. The treatments described herein for cancers can comprise cannabinoids such as cannabidiol (CBD), cancer therapeutics, terpenes, flavonoids, or combinations thereof.

The present application relates to a kind of lycopene and resveratrol microbead and preparation method thereof, to provide a kind of lycopene and resveratrol microbead capable of stable package, not only improve the solubility of two, and have significant antioxidant effect, can make active ingredient stable storage before use, belong to the skin care product technical field.

The present invention relates to a composition for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic low back pain (CLBP), chronic non- specific low back pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain conditions that affect (a) body area(s) or system(s) such as joints, tendons, ligaments, bones and / or muscles comprising delta-9-tetrahydrocannabinol (THC), alpha-bisabolol, guaiol, beta-caryophyllene and at least one additional terpene selected from the group consisting of linalool, alpha-humulene, nerolidol, caryophyllene oxide, alpha-pinene, camphene, beta-pinene, beta-myrcene, limonene, eucalyptol, ocimene, gamma- terpinene, terpinolene, alpha-terpinene, para-cymene, isopulegol and geraniol. The invention also relates to a pharmaceutical formulation for use in the treatment and / or prevention of chronic musculoskeletal pain, including chronic low back pain (CLBP), chronic non-specific low back pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain conditions that affect (a) body area(s) or system(s) such as joints, tendons, ligaments, bones and / or muscles comprising such a composition. The invention further relates to methods for treatment and or / prevention of chronic musculoskeletal pain, including chronic low back pain (CLBP), chronic non-specific low back pain (CNSLBP), osteoarthritis and / or other chronic musculoskeletal pain conditions that affect (a) body area(s) or system(s) such as joints, tendons, ligaments, bones and / or muscles. The invention further relates to kits comprising such a composition.

Homogeneous extract-infused cannabis biomasses, methods for their preparation, and products produced therefrom, such as pre-rolled joints, are provided. An exemplary method comprises steps of providing a cannabis extract; heating the cannabis extract; providing a milled cannabis plant material; applying the heated cannabis extract to the milled cannabis plant material using a predefined ratio of the cannabis plant material to the heated cannabis extract to provide an extract-applied plant material; and mixing the extract-applied plant material to provide a homogeneous extract-infused cannabis biomass, wherein there is less than a 15% variability in a target concentration of the at least one biomass cannabinoid, the at least one biomass terpene, or any combination thereof throughout a prepared batch and / or between alternate batches of the homogeneous extract-infused cannabis biomass.