15 results about "Lipid matrix" patented technology

The invention belongs to the technical field of cosmetics, and particularly relates to a lipidosome composite microemulsion sun-screening agent, a preparation method thereof and application of the lipidosome composite microemulsion sun-screening agent in cosmetics. According to the invention, by selecting specific chemical sun-screening agents for matching, full-wave-band ultraviolet protection is realized, and the sun-screening effect is improved; a specific solid lipid matrix is selected, a chemical sun-screening agent is dispersed in a lipid bilayer by using a coating technology, irritation caused by direct contact with skin is reduced, meanwhile, release of the sun-screening agent is delayed, long-acting sun-screening and light stability are improved, and a product formed by combining with a specific preparation method is smaller in particle size, more uniform in component distribution and higher in stability. Therefore, a uniform film layer is formed on the surface of the skin and is tightly attached to the skin, penetration of ultraviolet rays is reduced, and the skin feeling light effect and the film-forming property at high temperature are improved. The sun-screening agent disclosed by the invention has the advantages of efficient ultraviolet protection, excellent stability and good skin feeling, and a new technical scheme is provided for the field of sun-screening cosmetics.

Solid lipid nanoparticles (SLNs) for delivery of bioactive compounds are disclosed. The SLNs comprise a lipid matrix and surfactant layer encapsulating at least one bioactive compound selected from vitamins, minerals, enzymes, algae-derived bioactives, proteins, peptides, amino acids, antioxidants, small synthetic molecules, plant-derived volatile compounds, or botanical extracts. The SLNs exhibit submicron particle size, low polydispersity, and sufficient surface charge to ensure colloidal stability and efficient delivery. In one embodiment, algae-based bioactives, such as phycocyanin or fucoxanthin, are encapsulated using only natural and sustainable lipids and surfactants to improve bioavailability and support environmentally friendly formulations. The SLNs may be formulated for oral, topical, transdermal, injectable, ophthalmic, mucosal, textile, veterinary, or agricultural administration. Applications include human and animal health, functional foods, skincare, nutrient supplementation, and crop treatment. The disclosed SLNs offer a biocompatible and scalable delivery system that protects sensitive compounds, enables sustained release, and enhances absorption across diverse industries.

Stereoselective synthesis of 3,4-diamino-1,2-diols possessing a long hydrocarbon chain was carried out via olefin cross-metathesis between a commercial tetradec-1-ene and known diastereoisomeric trichloroacetamides prepared in our laboratory. Subsequent modification of the obtained coupling products used an approach based on functional group interconversions, which was accompanied by the rational choice of deprotection protocols. The resulting molecules represent novel isomeric amino analogues of natural D-ribo-phytosphingosine, which on the basis of their structure could have the status of skin sphingomimetics, i.e. substances that can affect the properties of the skin and dermis in terms of improving the quality of the lipid matrix (e.g. change in permeability, hydration), or stimulating the biosynthesis of procollagen in deeper structures. The cytotoxic effect of the prepared aminoisophytosphingosines was examined on two human non-malignant cell lines (BJ and HaCaT) and the screening results confirmed the safety in at least three representatives of the prepared series of compounds. In addition, the ability of the synthesized derivatives to inhibit cancer cell proliferation was also investigated. The results of preliminary anticancer screening showed weaker antiproliferative potential of these unusual sphingoid bases.

Solid lipid nanoparticles (SLNs) for delivery of bioactive compounds are disclosed. The SLNs comprise a lipid matrix and surfactant layer encapsulating at least one bioactive compound selected from vitamins, minerals, enzymes, algae-derived bioactives, proteins, peptides, amino acids, antioxidants, small synthetic molecules, plant-derived volatile compounds, or botanical extracts. The SLNs exhibit submicron particle size, low polydispersity, and sufficient surface charge to ensure colloidal stability and efficient delivery. In one embodiment, algae-based bioactives, such as phycocyanin or fucoxanthin, are encapsulated using only natural and sustainable lipids and surfactants to improve bioavailability and support environmentally friendly formulations. The SLNs may be formulated for oral, topical, transdermal, injectable, ophthalmic, mucosal, textile, veterinary, or agricultural administration. Applications include human and animal health, functional foods, skincare, nutrient supplementation, and crop treatment. The disclosed SLNs offer a biocompatible and scalable delivery system that protects sensitive compounds, enables sustained release, and enhances absorption across diverse industries.

A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.

A cosmetic system for sustained dermal delivery, characterized in that it comprises: • a first component (10) in a solid state, comprising an anhydrous lipid-based matrix and at least one bioactive agent, in particular a polynucleotide (PDRN), provided as surface-treated or encapsulated particles; • a second component (20) in a liquid state, comprising an aqueous activator mist (21) containing a non-ionic surfactant system and at least one penetration accelerator;• wherein the first component (10) is configured such that, upon contact with the activator mist (21), it undergoes an in-situ phase inversion from a solid lipid state, appearing as a solid track (11), to a resulting liquid serum state (12), characterized by a reduction in interfacial tension, which generates a capillary wicking effect for dermal delivery into skin microstructures (31) without the use of fibrous carrier substrates.

A dry powder inhalation formulation includes at least one active pharmaceutical ingredient (API) and a lipid matrix having at least one triglyceride chosen in the group consisting of monohydroxystearin, dihydroxystearin, trihydroxystearin and their mixture and its manufacturing method.

Process for coloring a lipid matrix blue from Ravenala madagascariensis arils. The invention relates mainly to a process for coloring a lipid matrix blue, which is essentially characterized in that it comprises at least the steps of: supplying or preparing a lipid matrix in liquid form; supplying or preparing seed arils of the plant species Ravenala madagascariensis; extracting the blue fat from the arils into the lipid matrix in liquid form, heated to a temperature between 40 and 60°C; and obtaining a blue-colored lipid composition. Depending on the nature of the lipid matrix used, the resulting lipid composition can be used in the cosmetic or food industries.

To provide a composition having a multiparticulate material capable of sufficiently incorporating a therapeutically effective amount of a fat-soluble active ingredient, having suitable efficacy and storage stability.SOLUTION: A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.SELECTED DRAWING: None

This invention belongs to the field of transdermal drug delivery nanocarrier technology, specifically relating to a nanoliposome using coconut oil as the lipid matrix and a specific Li medicinal herb composition (Alpinia oxyphylla + Artemisia argyi + Patchouli) as a natural penetration enhancer, and its preparation method. This product is a derivative of the core patent "A Natural Transdermal Permeation Enhancer Composition Based on Hainan Li Medicinal Herbs and Its Application" (patent application number: 2026106311990), used to significantly improve the transdermal efficiency and skin retention of the penetration enhancer composition, suitable for topical drugs and functional skin care products, realizing the industrialization extension of the core patent technology.

A composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein is disclosed. The active ingredient can include a fat-soluble active ingredient. The particles can be contained in a capsule. Also provided are methods for producing a pharmaceutical composition containing a plurality of particles containing a core having a lipid matrix including an active ingredient dispersed therein.

This invention is a "Bio-Active Therapeutic Skin Cream"; it is a scientifically formulated advanced Bio-Active Therapeutic Matrix, which is primarily composed of active ingredients derived from natural extracts; Organic Cold-Extracted (55599) Oils; Unrefined Shea Butter, Wax (Vitellaria paradoxa) (Cera alba) and Triple-Rendered Beef Tallow. The main benefits of this invention are: - Repairing the skin's natural moisture barrier function; - Treating severe skin dryness (Xerosis): - Itching (Pruritus): For the treatment and prevention of eczema (Atopic / Contact Dermatitis) and seborrheic dermatitis (Cradle Cap / Seborrheic Dermatitis) in children and adults without any side effects in all age groups. The product is an advanced industrial product and manufacturing process that is prepared by cold pressing and a slow infusion method (Cold Extended Infusion) for at least 2 weeks in a low-temperature controlled system to ensure that the active phytochemicals of the plant are fully integrated into the lipid matrix without being broken down or burned.

The invention is related to a process for separating lipids of differing degrees of unsaturation, comprising forming crystals in a lipid blend and separating liquid and solid fractions by a separation step The lipid blend is first cooled to a temperature below the crystallisation temperature of at least one higher-melting component to obtain a rigid solid lipid matrix, and the rigid solid lipid matrix is then subjected to centrifugal forces of at least 500g (RCF) to expel a liquid fraction enriched in lower-melting, more unsaturated lipids, the separation being carried out in the substantial absence of added solvent.

This invention proposes a multifunctional topical composition that integrates halogen-functionalized fullerenes (halo-fullerenes and halo-endofullerenes) and metallic nanoparticles (NPs) to provide comprehensive skin protection and sanitizing, cosmetic enhancement and in some embodiments, treatment for various conditions. Leveraging the atomic scale and physical characteristics of halogenated fullerenes for deeper tissue penetration, the composition can provide antioxidant, antimicrobial, and UV protective benefits to foster cellular integrity, proliferation, and differentiation as healthy tissue. The proposed formulation can penetrate the stratum corneum and diffuse into underlying skin layers due to atomic-scale NPs that can readily deliver active ingredients through the skin via the pores of sweat glands; the lipid matrix of the stratum corneum; and hair follicles, sebaceous glands, and pilosebaceous pores. This composition uses stable inorganic antibacterial agents with a robust safety profile. Furthermore, it can provide UV protection from harmful radiation. The formulation comprises active ingredients that are specific, safe, stable and effective—and can be produced economically, making it suitable for a broad range of skin protection, sanitizing, enhancement and therapeutic products that promote skin health and wellbeing.