65 results about "High pressure homogenization" patented technology

A composite encapsulated vitamin liposome, which is prepared from the following raw materials in parts by weight: 2-65 parts of a vitamin, 15-65 parts of a phospholipid, 0.2-3 parts of an antioxidant, 1-8 parts of a membrane stabilizer, 9-45 parts of a first-layer wall material, and 4-20 parts of a second-layer wall material. A preparation method comprises: preparing an aqueous solution of a water-soluble vitamin to obtain an aqueous phase; fully mixing and dissolving anhydrous ethanol, a phospholipid and a membrane stabilizer, and then adding a lipid-soluble vitamin and allowing same to completely dissolve to obtain an alcohol phase; separately preparing a first-layer wall material solution and a second-layer wall material solution; slowly injecting the alcohol phase into the aqueous phase, and stirring same sufficiently to form a primary liposome dispersion solution; performing vacuum concentration to obtain a concentrated solution, slowly adding same to the first-layer wall material solution, and stirring same sufficiently to form a dispersion solution; and performing high speed shearing and high pressure homogenization and mixing same with the second-layer wall material solution, and performing drying to obtain the final product. The liposome can be used in the production of tablet preparations, hard-shell capsules and solid beverages, and can achieve high stability and controlled release of vitamins.

The invention discloses diglyceride composite edible oil assisting in reducing blood sugar and blood fat and a preparation method thereof, and relates to the technical field of functional edible oil. The diglyceride composite edible oil for assisting in reducing blood sugar and blood fat is prepared from the following raw materials in parts by weight: 40 to 60 parts of high-purity diglyceride oil, 2 to 3 parts of modified flaxseed oil micro powder, 2 to 3 parts of modified camellia oleosa seed oil microcapsule powder, 5 to 8 parts of perilla seed oil, 2 to 5 parts of phytosterol ester, 1 to 3 parts of resistant dextrin, 0.1 to 0.5 part of rosemary extract and 0.05 to 0.15 part of potassium citrate. The compound edible oil is scientific in formula, and the high-purity diglyceride oil is used as a core and matched with various functional components such as the modified flaxseed oil micro powder to synergistically play a role in assisting in reducing blood sugar and blood fat. Through an exclusive modification process, gradient high-pressure homogenization and other standardized preparation processes, the stability and dispersion uniformity of the components are improved, the absorption rate of the active components is high, the storage life is long, no artificially synthesized additive is added, the food is safe to eat, and practicability and health are both considered.

The invention relates to a method for preparing high-solubility dendrobium officinale powder based on a polysaccharide enzymolysis technology, and belongs to the technical field of food processing. The invention relates to a method for preparing high-solubility dendrobium officinale powder based on a polysaccharide enzymolysis technology, which comprises the following steps of: crushing, grinding and sieving dendrobium officinale dry strips to obtain dendrobium officinale dry powder, and adding the dendrobium officinale dry powder into purified water to obtain dendrobium officinale dispersion liquid; heating the dispersion liquid in a water bath at 90-100 DEG C for 1-2 hours, centrifuging, and collecting supernate to obtain an extracting solution; and adding glycosidase into the extracting solution, carrying out enzymolysis at 40-60 DEG C for 1-1.5 hours, and carrying out enzyme deactivation, high-pressure homogenization and spray drying to obtain the high-solubility dendrobium officinale powder. By means of enzymolysis treatment, the yield of the effective component (polysaccharide) in the dendrobium nobile powder is increased. The method is easy to operate, mild in condition and relatively short in production period, other substances cannot be introduced, and adverse effects on the flavor of the prepared high-solubility dendrobium officinale powder cannot be caused.

A kind of epirubicin prodrug, albumin nanoparticle pharmaceutical composition comprising the prodrug and its preparation method and application.The long-chain fatty acid is connected with epirubicin by using acyl hydrazone bond sensitive to tumor acid microenvironment to construct epirubicin prodrug, so as to improve the binding capacity of epirubicin and albumin.The prepared epirubicin prodrug can realize the sufficient dissolution of prodrug using water as solvent, then mixed with albumin aqueous solution, and after high pressure homogenization, the uniformly distributed epirubicin-fatty acid prodrug albumin nanoparticle pharmaceutical composition can be obtained.The preparation process provided does not need to use organic solvent, breaks through the technical obstacle that existing albumin preparation product must use organic solvent to prepare, simplifies the preparation process, and at the same time avoids the risk of organic solvent residue and inducing albumin denaturation.

The invention relates to the technical field of food processing, and discloses a non-thermal processing technology of a health drink with ultrahigh pressure homogenization cooperating with HPP sterilization, the non-thermal processing technology comprises the following steps: S1, mixing raw materials with purified water, and carrying out rough processing through a colloid mill to obtain primary slurry; s2, inputting the primary slurry into an ultrahigh-pressure micro-jet homogenizer for homogenizing treatment, wherein the homogenizing pressure is 200-420 MPa; s3, performing sterile canning and sealing on the homogenized material liquid; and S4, the sealed product is subjected to HPP sterilization treatment, the sterilization pressure ranges from 100 MPa to 600 MPa, the pressure maintaining time ranges from 1 min to 10 min, and the treatment temperature is not higher than 25 DEG C. According to the invention, the damage of high temperature to the product quality is avoided through the dual effects of non-thermal ultrahigh pressure microjet homogenization and HPP sterilization in the whole process. The health-care beverage prepared by the process has excellent physical stability and is free of layering and precipitation; the retention rate of heat-sensitive nutritional ingredients is high, for example, the retention rate of dendrobium polysaccharides is not lower than 95%, and the retention rate of total polyphenols is not lower than 92%; meanwhile, the natural flavor and color are kept, the taste is fine and smooth, and microbial indicators meet the requirements.

The invention belongs to the field of pharmaceutical preparations, and provides an assembly material for indissolvable active transdermal mucosal drug delivery and a preparation method thereof. According to the invention, lipid cubic-phase nanoparticles composed of glyceryl monooleate, cholesterol, glycerol dioleate and caprylic / capric triglyceride are adopted, the design of DSPE-PEG2000 surface stability and ion coordinated regulation is combined, and high drug loading capacity and nanoscale particle size control are realized through a continuous process of melting, hydration, high-pressure homogenization and cubic-phase curing surface treatment. The preparation method solves the technical problems that high loading capacity of insoluble active ingredients and long-term colloidal stability are difficult to consider, cubic phase structure stability and surface charge controllability are contradictory in a tissue-friendly environment, and high drug loading capacity and devitrification prevention are difficult to couple under a low-temperature processing window, and has wide application value in the field of transdermal and mucosal local drug delivery.

The present invention discloses a formulation of bioactive liposomal gummies and a process of preparation thereof. The formulation comprises a bioactive component, an encapsulating agent, a sweetening agent, a flavoring agent, a gelling agent, an acidity regulator, a coloring agent, a bulking agent, a texturing agent, a thickening agent, a cross-linking polymer and water. The invention discloses a method of preparation of bioactive liposome using nano-milling process subsequently high-pressure homogenization, followed by a spray drying process. The process results in formulating dried bioactive liposomal gummies that exhibit increased stability and bioavailability of the liposomes making it a suitable for drug delivery system for wide range of bioactive agents. The bioactive liposomal gummies exhibit pH and temperature stability along with being palatable.

The invention relates to a digital printing paste composition for disperse digital printing wet sizing of a blanket fabric. The digital printing paste composition comprises nano starch; the special penetrating agent is formed by compounding polyglycerol ester and an organic silicon compound; a rheology modifier; a humectant; and a cross-linking agent. The preparation method of the digital printing slurry composition for disperse digital printing wet sizing of the blanket fabric comprises the following steps: stirring the nano starch, the special penetrant, the rheology modifier, the humectant and the cross-linking agent at a constant temperature for 30 minutes; the special penetrant is formed by compounding polyglycerol ester and an organic silicon compound, the special penetrant promotes dye to deeply permeate into blanket fibers, nano starch is adopted, the special penetrant is prepared through an acidolysis-high-pressure homogenization method, and the special penetrant has the characteristics of high specific surface area and low viscosity; therefore, the defects of the existing digital printing paste in key indexes such as color yield, permeability and uniformity are remarkably improved, and the overall quality of printed products is improved.

The application discloses a kind of high oil load mutton oil powder grease and its preparation method, belong to food processing technical field.The method is as follows: (1) preparation gelatin solution, join nanocellulose stirring to obtain composite liquid, then adjust pH, the non-ionic cellulose ether of addition is carried out high pressure homogenization to obtain suspension, then dry to obtain nanocomposite particle;(2) the nanocomposite particle in step (1) is dispersed in water as aqueous phase system, mutton oil is added as oil phase in aqueous phase and is sheared, high pressure homogenization obtains mutton oil pickering emulsion;(3) the mutton oil pickering emulsion of step (2) is added in plant polyphenol, and the modified mutton oil pickering emulsion is obtained;(4) the modified mutton oil pickering emulsion in step (3) is spray dried to obtain mutton oil powder grease.The application makes the oil load of mutton oil powder grease reach 90% without adding any small molecule surfactant, and mutton oil powder grease has good rehydration.

The present application belongs to the field of food contact coating materials, and provides a food contact grade silicone emulsion and a preparation method thereof. The silicone intermediate with a core-shell emulsion droplet structure is synergistically compounded with a methyltrimethoxysilane surface modified silica intermediate, and combined with hydrolysis and condensation pre-emulsification, high pressure homogenization, aging, defoaming, filtration and control of emulsion droplet and particle size distribution to obtain a water-based system with stable dispersion and workability. The system still maintains suitable viscosity under higher non-volatile conditions, and after film formation, it has the performances of adhesion, wear resistance, heat resistance and stable release, solving the problem that the existing system cannot simultaneously consider high solid content, low viscosity, processing adaptability, high adhesion, wear resistance and film forming performance, and high heat resistance, stability and low release force. The present application has application value in constructing a silicone release layer on the surface of paper base material and plastic film base material.

Disclosed is use of innovative technologies in the production of gelatine from animal tissues. The method is adapted to shorten the retention time of animal tissues to be stored in an acid or alkaline environment during the pre-treatment stage, to increase the extraction efficiency and to improve the functional properties of gelatine. The method includes the steps of the skins or bones that are the raw material of gelatine, ohmic system, ultrasound system, high hydrostatic pressure system, a high pressure homogenization system and microwave system technology selected from a group consisting of single, double, triple or quadruple combinations of collagen exposed to the inflating, conversion of inflated collagens into gelatine and performing the extraction process with the ohmic system.

The invention discloses a method for preparing schizophyllum commune polysaccharide through high-pressure homogenization and application of the schizophyllum commune polysaccharide, and belongs to the technical field of food and medical treatment. On the basis of a traditional water extraction and alcohol precipitation process, the molecular weight and viscosity of schizophyllum commune fermentation liquor polysaccharide are remarkably reduced through a high-pressure homogenization technology, the schizophyllum commune fermentation liquor polysaccharide is smoother in morphology, and meanwhile a triple-helix structure is maintained; the physical properties of the polysaccharide treated by the method are optimized, and the immunoregulation, anti-apoptosis and anti-oxidative damage activity are also remarkably enhanced. Furthermore, the polysaccharide-selenium nanoparticle compound is prepared from the polysaccharide, sodium selenite and L-ascorbic acid through a mild one-step oxidation-reduction method, the water solubility, biocompatibility and bioavailability of the polysaccharide can be effectively improved through the compound, and the polysaccharide-selenium nanoparticle compound shows more excellent apoptosis resistance and oxidation resistance in a model experiment.

The application discloses an adjustable high-pressure homogenization valve and a high-pressure homogenizer thereof. The valve seat is provided with a flow guide channel communicated with a homogenization pump set. The valve core is movably arranged at the outlet of the flow guide channel and has a gap for shearing materials between the valve core and the outlet. The valve core is connected with a driving mechanism for driving the valve core away from or close to the outlet. The materials passing through the flow guide channel and the outlet of the flow guide channel impact on the valve core. When passing through the gap, the materials form comprehensive effects such as pressure loss, expansion, explosion, shearing and high-speed impact. The material particles in the liquid are broken into small sizes. According to the requirements of different emulsification degrees and dispersion degrees of the materials, the driving mechanism adjusts the valve core away from or close to the outlet, so that the adaptability of the whole device during use is ensured. The outlet and the valve core are in a concave-convex structure in a nested mode. The concave-convex structure has a plurality of steps which are matched. The materials form multiple impacts between the steps, so that the sufficiency of the material particle breaking is ensured.

Microbial origin protein (MOP) is regarded as an alternative to feed and food grade protein, offering a sustainable solution (negligible land footprint and a water footprint 14 times lower than that of soybean) to partially support the increased supply needs. Our goal is to incubate methane-oxidizing bacteria (MOB) by using bubble column bioreactor (BCB) with internal gas recycling. The production process of microbial origin protein consists of 4 steps: (a) fermentation step using a bubble column bioreactor (BCB) with internal gas recycling (polypropylene with a thickness of 11 mm) and working volume of 20 L and column dimension of 11.8 cm as internal diameter (D) and 213.0 cm as height (H), and a H / D ratio of 18.05; (b) biomass harvesting and concentration using centrifugation during 15 min at 3500 rpm and 4°C; (c) High Pressure Homogenization (HPH) processing was used to homogenize the biomass in four passes at pressure levels of 150 MPa with a duration of 4 min between the different passes; and (d) Spray-drying of the biomass using a spray dryer equipped with a rotary atomizer and the atomization pressure was maintained at 0.6 MPa. The methanotrophic biomass obtained exhibited an outstanding nutritional value. More specifically, a high protein content (~62%) along with a balanced amino acids profile, covering all dispensable and non-dispensable AAs, was produced by this process. Moreover, the lipid content (~8%) was also comparable to other nutrient sources such as fishmeal (8%). All the results obtained, and all the parameters determined in the present study are sufficient to implement a bubble column bioreactor at industrial scale and to produce the microbial origin protein (MOP) for animal and human nutrition.

The invention herein disclosed refers to a method for preparation of glycerol nanocapsules (GNCs), adapted as an additive in a hydrophobic lubricant for improving lubricity in a tribological system, further to a glycerol nanocapsule (GNC) and finally to the respective use. The method comprises the steps of providing a continuous phase comprising at least a polyalphaolefin (PAO) and a dispersed phase comprising at least glycerol (GLY), of - mixing the continuous phase and the dispersed phase and performing high-pressure homogenization with a microfluidizer resulting in a minielmulsion comprising glycerol nanodroplets (GNPs). Further, adding a diisocyanate crosslinking agent (TDI) to the miniemulsion is comprised, leading to a polymerization reaction of the diisocyanate cross-linking agent (TDI) and glycerol (GLY) at the interfaces of the glycerol nanodroplets (GNPs) dispersed in the polyalphaolefin (PAO), resulting in formation of crosslinked glycerol-based polyurethan shells encapsulating a core of unreacted glycerol (GLY). Thereby glycerol nanocapsules (GNCs) are obtained, comprising a core of unreacted glycerol (GLY) encapsulated in a crosslinked glycerol-based polyurethan shell.

The invention relates to the technical field of food byproduct processing, in particular to a production process of a yellow wine vinasse flavor extract. The method comprises the following steps: firstly, performing soaking, fermentation, aging and solid-liquid separation on the yellow wine vinasse to obtain vinasse mud, adding grafted amylose into the vinasse mud for pre-soaking, and then adding grafted amylopectin for ultrasonic-high-pressure homogenization circulation treatment to obtain the superfine vinasse mud. Finally, propylene glycol and medium-chain triglyceride are used for constructing a temperature-resistant solvent, double grafted starch is supplemented for emulsification and homogenization, and the flavor extract is prepared. According to the method, a step-by-step synergistic extraction-double grafting embedding-oil phase heat barrier system is constructed, the problems that the utilization rate of vinasse flavor substance raw materials is insufficient and volatilization loss occurs under high-temperature processing are effectively solved, the obtained product is fine and smooth in texture, rich in flavor and excellent in heat resistance, and the application value of vinasse by-products is greatly improved.

The invention relates to a lithocarpus litseifolius compound plant beverage and a preparation method thereof, and belongs to the technical field of health drinks, and the lithocarpus litseifolius compound plant beverage comprises the following raw materials in parts by weight: lithocarpus litseifolius, eucommia ulmoides leaves, mulberry leaves, Chinese wolfberry fruits, haws, lotus leaves, emblic leafflower fruits, momordica grosvenori, dendrobe and gynostemma pentaphyllum. The preparation method comprises the following steps: grouping raw materials according to physical properties, performing low-temperature dynamic countercurrent extraction on heat-sensitive raw materials such as leaves, and performing stepped variable-temperature enzymolysis-hot extraction on compact raw materials such as fruit stems; after the two groups of extracting solutions are compounded in proportion, flavor self-blending is realized through low-temperature vacuum concentration; and performing pure physical refining and stabilization through ceramic membrane filtration and ultrahigh pressure homogenization, and finally sterilizing and filling. Through scientific compounding, refined segmented extraction and synergistic interaction, multiple health-care functions, excellent sensory quality and long-term stability under the condition of zero chemical addition are realized, and the product is all natural and suitable for industrial production.

The application belongs to the technical field of dispersion, and particularly relates to a high-pressure homogenizing device, which comprises a machine body, a discharging tank fixed to one side of the machine body, a discharge pipe fixed to the side of the machine body corresponding to the discharging tank, one end of the discharge pipe located directly above the discharging tank, a switching assembly arranged on one side of the machine body, the switching assembly comprising a fixed box fixed to one side of the machine body, a connecting pipe fixed to one side of the fixed box, one end of the connecting pipe fixed to the machine body, a first groove arranged in the fixed box, guide plates symmetrically arranged in the first groove, a switching piece arranged between the two guide plates, the switching piece used for switching the channel in the fixed box, the fixed box switching the homogenizing passage and the cleaning passage, and the connecting pipe used for feeding water into the fixed box for cleaning work.

The invention discloses a food containing high-purity alkaline compound vitamin C and a preparation process thereof, and belongs to the technical field of functional foods. The core is a microencapsulated particle prepared by using a liposome embedding technology, and the microencapsulated particle comprises alkaline vitamin C components such as sodium ascorbate and calcium ascorbate which are wrapped by a phospholipid bilayer; the shell layer is composed of foaming agents such as citric acid and sodium bicarbonate and flavor auxiliary materials. The process comprises the following steps: firstly, preparing lipidosome wrapped with vitamin C by adopting technologies such as high-pressure homogenization and the like, and then curing the lipidosome into microcapsule powder by adopting technologies such as spray drying and the like; performing wet granulation on the powder to obtain core particles; and finally, coating the shell powder on the surfaces of the inner core particles by adopting a powder coating process. Through dual protection of liposome embedding and core-shell physical isolation, the problem of chemical compatibility between an alkaline core and an acidic shell is fundamentally solved, the bioavailability of vitamin C is also improved, and meanwhile, the stability and excellent taste of the product are ensured.

The invention discloses a method for recovering valuable components from petrochemical waste residues, which belongs to the technical field of resource recovery and chemical metallurgy, and comprises the following steps: step (A): high-pressure homogenization treatment; step (B): vulcanization reaction; (C) oxidation alkaline leaching; (D) carrying out acid leaching on the alkaline leaching residues obtained in the step (C), and carrying out solid-liquid separation to obtain nickel-containing acid leaching liquid and acid leaching residues of which the main component is carbon; (E) precipitating vanadium and purifying; (F) neutralizing the vanadium precipitation tail liquid obtained in the step (E) by using acid, and carrying out ultrasonic washing and drying on the obtained solid to obtain molybdic acid; and (G) purifying the pickle liquor obtained in the step (D) to remove impurities, and carrying out evaporative crystallization on the obtained purified liquor to obtain nickel sulfate. According to the method disclosed by the invention, efficient separation and high-value utilization of carbon resources, molybdenum, vanadium and nickel are realized through a process route of high-pressure homogenization, anaerobic vulcanization, oxidation alkaline leaching, acid leaching and step-by-step purification.

The application discloses a nano-suspension preparation of juglone, which is mainly prepared from 5-15 parts of juglone and 1-20 parts of a stabilizer by weight. The application also adopts a reverse solvent method-high pressure homogenization method to establish a corresponding preparation method, which is simple in process and can obtain smaller drug particle size, thereby improving the drug bioavailability and enhancing the anti-tumor effect. Therefore, the application prepares a novel traditional Chinese medicine nano-preparation of juglone through the means of pharmacy, effectively improves the solubility and bioavailability of juglone. The in-vitro anti-tumor activity experimental results show that the nano-suspension preparation has significant inhibitory activity on the growth of various tumor cells, can be used for preparing drugs for preventing and treating related tumors, increases the targeting and bioavailability of the drug on tumors, reduces the toxicity, provides a new method and strategy for clinical treatment, and has good market prospect and high social value and economic value.

The invention discloses a plant cell vesicle and a preparation method thereof, and belongs to the technical field of biology. The preparation method comprises the steps of plant tissue pretreatment (adding cane sugar as an osmotic pressure protective agent), high-pressure homogenization (100-300MPa, 2-3 times), composite enzymolysis (mixing cellulase and pectinase, 35-45 DEG C, 10-30 minutes), differential centrifugation and ultracentrifugation (100,000 * g, 2 hours) combined purification. The average particle size of the obtained vesicle is 50-200nm, and the vesicle can be used for drug molecule or nucleic acid delivery. By optimizing parameters and additives in each step, the yield, structural integrity and functional characteristics of the vesicles are remarkably improved, and technical support is provided for application of the plant-derived vesicles in the field of nano-drug delivery.

According to the rukotinib phosphate cream and the preparation method thereof provided by the invention, in the preparation process, more sufficient emulsification is carried out by adopting a high-shearing and high-pressure homogenizing mode, so that the prepared cream is fine and smooth in texture, stable in physical property and free of toxic and side effects; the characteristics, the droplet particle size, the dynamic viscosity and the in-vitro release rate of the emulsifiable paste are stable under the accelerated or long-term placement condition, the unstable phenomena of layering, water bleeding and the like of the emulsifiable paste in a short time are avoided, the continuous safety and the curative effect stability of the emulsifiable paste in the using process are ensured, and the preparation method is simple, high in operability and suitable for industrial production. The method is suitable for large-scale industrial production.

The invention relates to milk powder for improving child anorexia and a preparation method thereof, which comprises the following steps: putting low-temperature soybean meal as a raw material into a tank, adding 9 times of water at the water temperature of 30-40 DEG C, stirring in the tank, feeding into a high-speed separator, separating soybean dregs, carrying out acid precipitation, separation, neutralization, sterilization and drying treatment on protein water, carrying out low-temperature superfine grinding on dried protein powder by using a superfine grinding machine, and packaging to obtain the milk powder for improving child anorexia. The preparation method comprises the following steps: uniformly mixing whey protein powder, fresh milk, fructo-oligosaccharide, galactooligosaccharide, milk mineral salt, compound trace elements and compound vitamins to obtain a mixed material liquid, and carrying out homogenization, high-pressure homogenization, sterilization, concentration and spray drying on the obtained mixed material liquid to obtain the milk powder. The milk powder, the soybean protein micro powder, the docosahexaenoic acid fish oil powder, the arachidonic acid grease and the composite probiotic powder are uniformly mixed to finally obtain the infant formula milk powder, and the milk powder obtained by the method is quick to dissolve, promotes digestion and has the effects of obviously improving food retention, constipation and anorexia.

The application discloses a kind of salt fog resistant nano organic clay rheological agents and preparation method thereof.The rheological agent includes boehmite 8-15 parts, sodium bentonite 24-60 parts, quaternary ammonium salt 20-40 parts, silane coupling agent 1.5-4.8 parts, structure directing agent 1.5-4.5 parts, dispersant 0.1-0.3 parts by weight fraction.Preparation method includes boehmite nanocrystal hydrothermal synthesis, bentonite ultrasonic-high pressure homogenization synergistic exfoliation, quaternary ammonium salt ion exchange intercalation modification, in-situ composite assembly, silane coupling agent surface modification and product forming and other key steps.By the layered structure of boehmite nanocrystal and bentonite sheet layer form synergistic composite, after silane coupling agent chemical bonding modification, build stable organic-inorganic composite structure.The rheological agent shows excellent rheological regulation performance, salt fog corrosion resistance and environmental adaptability, suitable for harsh environment such as marine engineering rheological regulation application.

The invention discloses micronized whey protein as well as a preparation method and application thereof. In order to improve the stability of whey protein in ultra-high temperature (UHT) processing, a hot shearing-high pressure homogenization synergistic technology is combined with carbohydrate addition to prepare micronized whey protein (MWP), and the thermal stability of the micronized whey protein is systematically evaluated. The result shows that the denaturation degree of the MWP after micronization processing is increased. The MWP prepared under the conditions of neutral pH (6.6) and high protein concentration (greater than or equal to 9%) has excellent thermal stability, and still keeps good fluidity after UHT treatment. The invention provides an effective modification approach and theoretical support for developing a high-protein whey product suitable for a UHT process.

The application discloses a kind of from ginkgo leaf residue extraction polysaccharide and aglycone flavonoid bacteria-enzyme synergistic method, belong to ginkgo leaf residue resource comprehensive utilization technical field, including the following steps: (1) high-temperature steam sterilization;(2) aspergillus niger fermentation;(3) ultrasonic wave, hydrothermal extraction;(4) concentration, alcohol precipitation;(5) complex enzyme enzymolysis;(6) homogenization, alcohol hydrothermal extraction.The method of the application, using aspergillus niger and complex enzyme synergism, and combining ultrasonic wave, microjet high pressure homogenization etc., polysaccharide, flavonoid active ingredient in ginkgo leaf residue is extracted, biotransformation, realize that polysaccharide and aglycone flavonoid content in leaf residue is improved, and the "titer" of ginkgo polysaccharide, flavonoid is promoted.

The invention belongs to the technical field of food seasoning processing, and particularly discloses a kelp and skipjack double-enzymolysis coupled Maillard aroma enhancement concentrated solution and a preparation method thereof. The preparation method comprises the following steps: rehydrating dried kelp powder, ground skipjack, euphausia superba powder and the like which are used as raw materials, and sequentially carrying out stepped double-enzymolysis, solid-liquid separation, Maillard reaction aroma enhancement, ultrahigh-pressure homogenization, concentration and blending, sterilization and filling. Rich flavor precursor substances such as amino acid, small molecule peptide and reducing sugar are efficiently released through a double-enzymolysis strategy, then rich and coordinated grilled fish and seafood characteristic flavor is generated through a controllable Maillard reaction, and finally the problem of product stability is solved through ultrahigh pressure homogenization. The concentrated solution prepared by the method is natural and mellow in flavor and uniform and stable in posture, can be widely applied to the fields of compound seasonings, leisure foods, prefabricated dishes and the like, and provides a new way for developing high-end natural seafood flavor products.

The present application provides a kind of straw / high density polyethylene color composite material preparation method, steps are: with straw as raw material, washing, drying, section after microwave treatment;Straw is bleached using ultrasonic assisted bleaching technology;With nano attapulgite as color fixing agent, combine ultrasonic and high pressure homogenization treatment technology to color fixing iron oxide pigment, prepare straw / high density polyethylene color composite material by vacuum hot pressing forming process and vacuum heat fixing technology.The present application solves the problems of poor color stability, color number adjustment is greatly influenced by original color of straw and other problems in the preparation of color composite material by directly adding pigment or colorant in traditional preparation process, gives straw / high density polyethylene composite material stable color, and further expands the application range of straw / high density polyethylene composite material.

This invention belongs to the field of pharmaceutical formulations and provides an assembly material and preparation method for transdermal and mucosal drug delivery of poorly soluble active ingredients. The invention utilizes lipid cubic phase nanoparticles composed of monooleate glycerol, cholesterol, dioleate glycerol, and caprylic / capric triglycerides. Combined with the surface stabilization and ion-synergistic regulation design of DSPE-PEG2000, a continuous process of melting-hydration-high pressure homogenization-cubic phase curing surface treatment is employed to achieve high drug loading and nanoscale particle size control. This invention solves the technical problems of balancing high loading of poorly soluble active ingredients with long-term colloidal stability, the contradiction between cubic phase structure stability and surface charge controllability in tissue-friendly environments, and the difficulty of achieving high drug loading and preventing crystallization coupling under low-temperature processing windows. It has broad application value in the fields of transdermal and mucosal local drug delivery.