24 results about "Schizophyllum commune" patented technology

The invention discloses endophyte Schizophyllanthus commune CY01-1H for improving synthesis of jasmonic acid and dendrobine of dendrobium nobile seedlings and application of the endophyte Schizophyllanthus commune CY01-1H, and belongs to the technical field of plant secondary metabolism regulation and control and microorganisms. The preservation number of the endophyte CY01-1H is CGMCC (China General Microbiological Culture Collection Center) No.42003; the strain is preserved in China General Microbiological Culture Collection Center on May 12, 2025, and the address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing; the endophytic fungus CY01-1H obtained through separation comes from a healthy dendrobium nobile plant, the content of jasmonic acid of dendrobium nobile and accumulation of dendrobine can be increased by planting the endophytic fungus CY01-1H in dendrobium nobile, the normal growth state of the plant is not affected, and wide application prospects are brought for improving the quality of the dendrobium nobile medicinal material.

The invention provides a red rice / mung bean fermentation mud film and a preparation method thereof.The preparation method comprises the steps that 1, red rice is weighed, a proper amount of water is added, or soaked mung beans are weighed, and after high-temperature sterilization, the mung beans are cooled to the room temperature, and a substrate is obtained; step 2, inoculating a schizophyllum commune seed solution or a lucid ganoderma seed solution into the substrate, and standing for fermentation culture to obtain a fermented product; and step 3, adding water into the fermented product, and sequentially carrying out homogenization, grinding, sterilization and preservative treatment to finally obtain the red rice / mung bean fermented mud film. According to the method, the red rice or mung bean fermentation product can be effectively utilized, the moisture retention performance and sensory comfort of the product are remarkably improved while the mud mask is endowed with strong cleaning power, and various mineral raw materials can be replaced or partially replaced to prepare the mud mask. Especially, the red rice fermented mud film has extremely strong immediate oil control performance and purification effect, good moisturizing and moisturizing effects, no irritation to skin melanocytes, no pigmentation after inflammation, and good skin smoothing effect.

The application discloses a strain of Burkholderia gladioli CT-5 and application thereof, and relates to the technical field of microorganisms. The strain is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC NO: M20242732, and the preservation date is December 5, 2024. The Burkholderia gladioli CT-5 provided by the application has a significant prevention and treatment effect (P<0.05) on root rot of Idesia polycarpa caused by Fusarium solani, and has a significant inhibitory effect on other various plant pathogenic fungi such as Schizophyllum commune, Diaporthe eres and Colletotrichum acutatum. In a pot experiment, the biomass of Idesia polycarpa seedlings, soil nutrients, SOD, POD and CAT enzyme activities of the CT-5 treatment group are significantly improved (P<0.05) compared with the pathogenic fungus control group (FP), indicating that the strain can promote plant growth, activate the activity of defense enzymes in the body, and thus effectively control the root rot of Idesia polycarpa, which provides strong theoretical basis and technical support for the sustainable development of Idesia polycarpa.

The invention relates to the field of cosmetics, in particular to high-transparency schizophyllum commune polysaccharide, a preparation method thereof and cosmetics. The method comprises the following steps: freezing a schizophyllum commune fermentation mixture containing mycelia under a negative temperature condition to obtain a frozen product; unfreezing the frozen product to obtain an unfrozen mixture; centrifuging the unfrozen mixture, filtering to remove mycelium, and collecting fermentation filtrate; adding absolute ethyl alcohol with the same mass into the fermentation filtrate for alcohol precipitation of polysaccharide to obtain polysaccharide precipitate; collecting polysaccharide precipitates, and repeatedly washing the polysaccharide precipitates with an ethanol solution to obtain washed polysaccharide precipitates; and centrifuging the washed polysaccharide precipitate, collecting the centrifuged polysaccharide precipitate, and redissolving the polysaccharide precipitate in the solvent. According to the technical scheme, the freezing and thawing step is specifically applied to the mycelium-containing schizophyllum commune fermentation mixture, and the colorless schizophyllum commune polysaccharide with excellent transparency is obtained by taking secreted exopolysaccharide as a main target for non-pure mycelium.

The invention discloses a method for preparing schizophyllum commune polysaccharide through high-pressure homogenization and application of the schizophyllum commune polysaccharide, and belongs to the technical field of food and medical treatment. On the basis of a traditional water extraction and alcohol precipitation process, the molecular weight and viscosity of schizophyllum commune fermentation liquor polysaccharide are remarkably reduced through a high-pressure homogenization technology, the schizophyllum commune fermentation liquor polysaccharide is smoother in morphology, and meanwhile a triple-helix structure is maintained; the physical properties of the polysaccharide treated by the method are optimized, and the immunoregulation, anti-apoptosis and anti-oxidative damage activity are also remarkably enhanced. Furthermore, the polysaccharide-selenium nanoparticle compound is prepared from the polysaccharide, sodium selenite and L-ascorbic acid through a mild one-step oxidation-reduction method, the water solubility, biocompatibility and bioavailability of the polysaccharide can be effectively improved through the compound, and the polysaccharide-selenium nanoparticle compound shows more excellent apoptosis resistance and oxidation resistance in a model experiment.

The invention discloses a schizophyllum commune seaweed fermentation product as well as a preparation method and application thereof, and belongs to the technical field of microbial fermentation. According to the method, the strain schizophyllum commune AD245 is fermented in a schizophyllum commune fermentation culture medium containing seaweed to prepare the schizophyllum commune seaweed fermented product, and the schizophyllum commune seaweed fermented product with high polyphenol and polysaccharide content is economically and efficiently prepared through the promoting effect of the seaweed on schizophyllum commune fermentation and the catalytic degradation effect of the schizophyllum commune on the seaweed; the fermentation method provided by the invention is simple and easy to implement, green and environment-friendly, and the prepared schizophyllum commune seaweed fermentation product has the effects of moisturizing and absorbing moisture, also has good DPPH free radical scavenging activity and hydroxyl free radical scavenging activity, can remarkably promote the production of collagen and elastin, plays a role in delaying senescence, and can be used for preparing the schizophyllum commune seaweed fermentation product. The schizophyllum commune seaweed fermentation product has important significance in cosmetics with the effects of improving moisture retention, oxidation resistance, anti-aging activity and the like, the application range of schizophyllum commune AD245 is further widened, and the schizophyllum commune seaweed fermentation product has wide application prospects.

The invention belongs to the technical field of fermentation, and relates to a preparation method of schizophyllum commune mycelium fermentation liquor and a product and application of the schizophyllum commune mycelium fermentation liquor, the preparation method comprises the following steps: inoculating schizophyllum commune into a culture medium, and standing and culturing to obtain primary seed liquor; the first-stage seed solution is inoculated into a culture medium and cultured, a second-stage seed solution is obtained, and culture comprises a standing culture stage and a stirring culture stage which are alternately carried out; and inoculating the secondary seed solution into a culture medium, fermenting, carrying out filter pressing on the obtained fermentation liquid, and collecting filtrate, thereby obtaining the product. According to the method, more schizophyllum commune mycelia are obtained by controlling the preparation mode of the seed liquid, the obtaining of schizophyllum commune polysaccharide during fermentation is promoted, the heavy metals possibly existing due to the heavy metal enrichment capacity of macro fungi are reduced by using the schizophyllum commune mycelia for fermentation, the quality of each batch of products is better controlled, the cost is remarkably reduced, and the method is suitable for industrial production. And the damage to the environment is reduced to a certain extent.

The application discloses a preparation method and application of a nitraria tangutorum bobr. fermentation liquor with whitening and firming effects, and the preparation method comprises the following steps: (1) crushing nitraria tangutorum bobr. fruits, adding water to obtain a fermentation substrate A, inoculating schizophyllum commune in the fermentation substrate A to perform preliminary fermentation, and obtaining nitraria tangutorum bobr. fruit fermentation liquor; (2) adding nitraria tangutorum bobr. leaves to the nitraria tangutorum bobr. fruit fermentation liquor to obtain a fermentation substrate B, and performing secondary fermentation in the fermentation substrate B by inoculating the schizophyllum commune again to obtain the nitraria tangutorum bobr. fermentation liquor. The fruits and leaves of nitraria tangutorum bobr. are subjected to stage fermentation, active substances in the nitraria tangutorum bobr. fruits are released in the first fermentation process, the nitraria tangutorum bobr. leaves are added to the nitraria tangutorum bobr. fruit fermentation liquor in the second fermentation process, active substances in the nitraria tangutorum bobr. leaves are further extracted, and decomposition of the active substances in the nitraria tangutorum bobr. leaves is avoided. The nitraria tangutorum bobr. fermentation liquor is subjected to multiple fermentation, release of the active substances in the nitraria tangutorum bobr. fermentation liquor is improved, ideal whitening, firming and other effects are achieved, and the nitraria tangutorum bobr. fermentation liquor has a good application prospect.

The present application discloses a schizophyllum commune fruiting body polysaccharide with anti-inflammatory activity and application thereof, the molecular weight of the polysaccharide is 1.87*10 4 Da, the sugar content is 96.41%+ / -2.12, and the molar ratio of monosaccharide composition is mannose:glucose:galactose:arabinose:fucose=9.057:9.633:9.631:1.561:1. The schizophyllum commune fruiting body polysaccharide of the present application shows excellent anti-inflammatory activity, has good development and utilization prospect, and can be widely applied in the fields of health-care food and medicine.

The invention discloses a method for preparing tea fermentation liquor through multi-bacteria mixed fermentation, the tea fermentation liquor and application of the tea fermentation liquor. The method comprises the steps that tea powder and a fermentation substrate are mixed and sterilized, and a pre-fermentation system is obtained; a macro fungus fermentation stage: inoculating the pre-fermentation system with the schizophyllum commune seed solution according to 4-8% of the volume of the fermentation substrate, and fermenting to obtain a schizophyllum commune fermentation system; a yeast fermentation stage: inoculating the kluyveromyces marxianus seed solution and the isatis orientalis seed solution into the schizophyllum commune fermentation system according to 2-4% of the volume of the fermentation substrate, and fermenting to obtain a yeast fermentation system; a bacterial fermentation stage: inoculating the acetobacter xylinum seed solution into a yeast fermentation system according to 4-8% of the volume of the fermentation substrate, and fermenting to obtain a mixed fermentation system; and post-treatment: carrying out inactivation, high-pressure homogenization and solid-liquid separation on the mixed fermentation system, and taking the liquid for sterilization and corrosion prevention to obtain the tea fermentation liquid. And cross-genus synergistic interaction is realized by a specific strain combination and a segmented culture process, and the multi-dimensional effect of a fermentation product is improved.

The invention relates to a composition with an eye enlarging effect and application of the composition. The composition is prepared from soluble collagen, tocopheryl nicotinate, acetyl hexapeptide-8, hydrolyzed rice protein, acetyl tetrapeptide-5, Arabic gum, rhizobium gum, an arnica extract and schizophyllum commune fermentation product filtrate. By compounding a plurality of plant extracts and polypeptides for use, excellent effects of tightening, lifting, removing pouches and reducing melanin can be realized, and the eye cream has a visual eye enlarging effect and is more young.

The invention provides a preparation method of a rhizoma polygonati extract for relieving fatigue. The preparation method comprises the following steps: obtaining a rhizoma polygonati raw material; performing steam explosion on the rhizoma polygonati raw material; inoculating epicoccum nigrum and schizophyllum commune into the rhizoma polygonati subjected to steam explosion to obtain a solid fermentation product; adding 4-20 times of water into the solid fermentation product, adjusting the pH value to 5.5-8.5 and the temperature to 40-60 DEG C, then adding ficin protease and neutral cellulase, and carrying out enzymolysis for 2-6 hours to obtain an enzymatic hydrolysate; inoculating rhodotorula glutinis with the initial concentration of 1-8 * 10 < 7 > cfu / g and bacillus cereus with the initial concentration of 1-8 * 10 < 9 > cfu / g into the enzymatic hydrolysate, and fermenting for 2-6 days to obtain secondary fermentation liquor; performing sterilization treatment on the secondary fermentation liquid to obtain an extracting solution; clarifying the extracting solution to obtain a clarified solution; and decolorizing the clarified liquid to obtain the rhizoma polygonati extract. According to the preparation method provided by the invention, the obtained rhizoma polygonati extract is high in polysaccharide content, high in yield, good in water solubility, relatively good in fatigue relieving effect and suitable for industrial popularization.

The invention discloses a strain of schizophyllum commune DKK and application thereof in prevention and treatment of rice and wheat diseases, the strain is preserved in China General Microbiological Culture Collection Center (CGMCC), the preservation date is May 19, 2025, the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC No.42010. The DKK strain is separated from persimmon fruits on which sporocarp grows. Researches show that the strain DKK inhibits the growth of rhizoctonia solani through antagonism and hyperparasitism; and the compound also has relatively good antagonistic activity on other pathogenic bacteria such as cochliobotrys miyabeanus, fusarium graminearum, wheat stem rot pathogen, potato late blight pathogen, tomato fusarium wilt pathogen, sclerotium fistulosum, strawberry botrytis cinerea, colletotrichum gloeosporioides and ligustrum japonicum leaf spot pathogen.

This invention relates to a composition for inhibiting inflammation and hyperpigmentation, and its application. The composition comprises the following components: tranexamic acid, oat β-glucan, Schizophyllum commune fermentation product filtrate, and plant extracts. By using a combination of cost-effective components, this invention achieves multi-dimensional anti-inflammatory and repairing effects, resulting in highly effective hyperpigmentation prevention.

The invention relates to an all-natural cosmetic matrix and application thereof. The cosmetic matrix is prepared from schizophyllum commune polysaccharide, squalene, natural lecithin, camellia-seed oil, oat kernel oil, lysozyme and caesalpinia spinosa gum. The invention develops the cosmetic composition from all natural food materials, the seven specific components are compounded for use, the stability of the system can be realized without adding an additional stabilizer, the longer shelf life of the system can be met without adding an additional preservative, and meanwhile, the cosmetic composition is suitable for being used in the fields of cosmetics, cosmetics, cosmetics and the like. The composition also has excellent skin moisturizing and repairing effects, is comfortable in skin feeling, mild and non-irritant to the skin, simple in formula, green, safe and environment-friendly, can be used as a cosmetic matrix for preparing cosmetic products of various dosage forms, and has a wide prospect.

The application relates to the field of cosmetics, and relates to beta-(1,3)-(1,6)-glucan and a preparation method and cosmetics thereof. Fermentation seed liquid is inoculated into a culture medium for fermentation; the culture medium comprises, in percentage by mass, 1-5% of glucose, 0.5-5% of tryptone, 0.1-1% of yeast extract powder, 0.01-0.1% of magnesium sulfate, 0.05-0.5% of potassium dihydrogen phosphate and the balance of water; in the culture medium, the concentration of vitamin B1 is 5-20 mg / L; and the concentration of folic acid is 1-8 mg / L. The fermentation strategy of using the culture medium containing vitamin B1 and folic acid in the above content range for fermentation can be used to prepare beta-(1,3)-(1,6)-glucan produced by schizophyllum commune, can significantly increase the weight of schizophyllum commune mycelium in the same time, effectively improves the content of beta-(1,3)-(1,6)-glucan, and has the advantages of shortening the production cycle and reducing the production cost.

The application relates to the field of cosmetics, in particular to a soapberry fermentation filtrate, a preparation method thereof and cosmetics. A preparation method of a soapberry fermentation filtrate, the method comprising the following steps: culturing and fermenting water-extracted soapberry residues and schizophyllum commune liquid in a culture medium, and taking a filtrate. In the application, the water-extracted soapberry residues and the schizophyllum commune liquid are cultured, the components which are not dissolved in water can be dissolved by biological fermentation, the soapberry fermentation filtrate can be used to develop cosmetics with the effects of improving skin barrier, removing yellow and brightening, and thus the utilization rate of soapberry is greatly improved, and the recyclability of resources is improved.

The invention discloses a novel schizophyllum commune strain and an artificial cultivation method thereof, the optimum carbon source of schizophyllum commune hyphae is cane sugar, the optimum nitrogen source is yeast extract powder, the optimum pH is 5.0, the optimum temperature is 32 DEG C, optimized 78% of mulberry sawdust, 20% of wheat bran, 1% of lime and 1% of gypsum are used as matrix cores, and a low-temperature induction and constant-temperature high-humidity fruiting mode is matched, after inducing for about 20 days at the low temperature of 18 DEG C, managing fruiting at the temperature of 25 DEG C and the relative humidity of 90%-95%, and realizing the high-yield stable performance that the average is 133.39 g / bag and the biological efficiency is 66.70%. Compared with the prior art, the method has the advantages that the method is standardized, can be copied, is suitable for large-scale and factory popularization, can effectively solve the problems that the traditional schizophyllum commune cultivation is unstable in yield and low in efficiency, and has remarkable industrial application value.

The invention discloses a ganoderma lucidum spore oil composite fungal polysaccharide anti-tumor oral preparation and application thereof. The ganoderma lucidum spore oil composite fungal polysaccharide anti-tumor oral preparation comprises the following components in percentage by weight: 15-25% of ganoderma lucidum spore oil; 10%-15% of composite fungal polysaccharide; 1%-3% of coenzyme Q10; 1%-2% of a nano encapsulation carrier; the auxiliary materials comprise 3%-6% of phospholipid and 0.3%-0.8% of vitamin E; the balance is sterile water; the grifola frondosa polysaccharide activates macrophages, the schizophyllum commune polysaccharide enhances NK cytotoxicity, the agaricus blazei murill polysaccharide inhibits angiogenesis, and the cordyceps sinensis polysaccharide regulates immune balance, so that a triple synergistic network of direct killing, immune activation and blood vessel blocking is formed; by adopting a membrane emulsification technology of a sodium caseinate-chitosan composite carrier, the problem of co-delivery of fat-soluble and water-soluble components is solved; the positive charge characteristic of chitosan realizes targeted delivery; by means of component innovation, process optimization and mechanism breakthrough, inherent defects of existing fungus anti-tumor preparations are overcome, and a brand new solution is provided for efficient and low-toxicity tumor adjuvant therapy.

This invention belongs to the field of microbial fermentation technology and relates to a method for increasing ethanol production through mixed fermentation of *Lactobacillus bakerella* and *Schizophyllum commune*. The steps include: inoculating activated *Schizophyllum commune* and activated *Lactobacillus bakerella* into a fermentation medium for fermentation; the ratio of *Schizophyllum commune* to *Lactobacillus bakerella* is 8.0 × 10⁻⁶. 5 CFU / mL: (5.00×10 7 CFU / mL-1.10×10 8 (CFU / mL). This invention can increase ethanol fermentation yield and provides a basis for industrial applications.

The invention relates to the field of cosmetics, in particular to an anti-aging cosmetic and a preparation method thereof. Based on the total mass of the anti-aging cosmetic, the anti-aging skin care composition is prepared from the following components in percentage by mass: 0.01 to 2 percent of engelhardia roxburghiana leaf extract, 0.01 to 2 percent of olive fruit extract, 0.01 to 2 percent of plantago major extract, 0.1 to 10 percent of schizophyllum commune fermentation product filtrate and 0.1 to 5 percent of soluble collagen. According to the technical scheme, the anti-aging composition uses the plant extracts as the raw materials to achieve the anti-aging effect, the product is mild and suitable for sensitive people to use, and meanwhile, starting from multiple dimensions such as oxidation resistance, collagen supplement, saccharification resistance, inflammation resistance and free radical resistance, the faster and stronger anti-aging effect is achieved through the combined action of multiple anti-aging mechanisms. Through scientific screening and accurate proportioning of the five specific active ingredients, synergistic interaction is realized, and the effects of resisting oxidation, removing wrinkles and delaying senescence are greatly improved.

The invention relates to the technical field of fermentation engineering and medicines, and discloses a high-yield production method of hispidulin, which comprises the following steps: (1) preparing a nutrient solution, (2) preparing a solid fermentation conversion culture medium, (3) directionally converting solid fermentation, and (4) extracting hispidulin. According to the method, a powerful enzyme system of schizophyllum commune is utilized to perform biotransformation on the traditional Chinese medicine scutellaria baicalensis which is extremely low in homoplantaginin content (or cannot be detected), so that oriented biotransformation of the homoplantaginin of main flavone in scutellaria baicalensis flavone is realized, and high-yield production of the homoplantaginin is realized. The method has the characteristics of high hispidulin directional conversion efficiency, simple operation, cheap raw materials and the like, provides a new technology and a new method for research and development of new hispidulin-containing medicines, functional foods and cosmetics, and has important application prospects and remarkable economic benefits.

The invention relates to the field of hair care, in particular to an anti-hair-loss and hair-strengthening composition and an anti-hair-loss and hair-strengthening hair care product. The hair-loss-preventing and hair-strengthening hair care product is prepared from the following components in percentage by mass: 1 to 5 percent of schizophyllum commune fermentation product filtrate, 0.005 to 0.05 percent of recombinant XV II type collagen, 0.005 to 0.05 percent of recombinant keratin, 0.01 to 1 percent of recombinant double collagen, 0.0005 to 0.005 percent of DNA sodium and 0.5 to 5 percent of cacumen biotae extract. According to the scheme, all the raw materials are synergistically matched, alopecia counting, local hair density, scalp percutaneous moisture loss (a barrier function) and cuticle moisture content are remarkably improved through multi-channel and multi-target anti-alopecia hair fixing, and the effect is fast and continuous.

This invention relates to the field of microbial fermentation technology, and particularly to a co-culture fermentation broth of medicinal and edible fungi with whitening effects, its preparation method, and its application. The preparation method of the co-culture fermentation broth of medicinal and edible fungi with whitening effects includes: inoculating the seed liquid of a first fungus and the seed liquid of a second fungus into a co-fermentation medium for fermentation and co-culture to obtain the co-culture fermentation broth of medicinal and edible fungi with whitening effects; the first fungus includes at least one of *Ganoderma lucidum* strain, *Trametes versicolor* strain, *Poria cocos* strain, *Auricularia auricula-judae* strain, *Phellinus linteus* strain, and *Aspergillus schavar*; the second fungus includes *Schizophyllum commune*. This invention co-cultures *Schizophyllum commune* with other specific strains and found that co-culturing the two strains can exert a synergistic effect, thereby significantly improving the tyrosinase inhibition effect of the fermentation broth. The optimal combination of fermentation broth can achieve a tyrosinase inhibition rate of over 90%, and even 1 wt% of the fermentation broth has a tyrosinase inhibition effect of approximately 90%.