30 results about "Schizophyllan" patented technology

The present application relates to the field of cosmetic technology, and more particularly to a full-link whitening and freckle-removing liposome and a preparation method thereof, the liposome comprising the following components: an aqueous phase, a membrane material and an oil phase. In the preparation process, 4-butyl resorcinol, nonapeptide-1, acetylchitosamine and ascorbic acid tetraisopalmitate are combined to form a full-link effect of signal inhibition-synthesis blockage-blocked conversion-metabolic acceleration, and a multi-target whitening and freckle-removing system is constructed. In addition, tranexamic acid, hydrolyzed yeast protein and schizophyllan are combined to synergistically make the finished product have excellent soothing and moisturizing effects. Furthermore, the finished product is prepared into a liposome capable of encapsulating active ingredients, which effectively improves the stability of the active ingredients, prevents their oxidation and inactivation, and the liposome structure is highly similar to the human cell membrane, is easy to penetrate the keratin layer gap, realizes targeted delivery to the deep layer of the epidermis, and makes the active ingredients truly act on the required site.

The invention provides a skin repair composition, a skin repair product and application of the skin repair composition and the skin repair product. The skin repair composition comprises the polydeoxyribonucleotide and the salt thereof, the Ectoine or the derivative thereof and the schizophyllan, overcomes the defect of single function of bioactive substances, and has the effects of inhibiting expression of inflammatory factors and accelerating repair of damaged skin pigmentation. The three active ingredients in the skin repair composition are not simply superposed, but generate a synergistic gain effect of '1 + 1 + 1gt, 3', the safety and effectiveness are obviously superior to those in the prior art, and a brand-new and excellent solution is provided for solving the problems of light and moderate acne of teenagers and hyperpigmentation after healing.

The invention relates to the field of cosmetics, in particular to high-transparency schizophyllum commune polysaccharide, a preparation method thereof and cosmetics. The method comprises the following steps: freezing a schizophyllum commune fermentation mixture containing mycelia under a negative temperature condition to obtain a frozen product; unfreezing the frozen product to obtain an unfrozen mixture; centrifuging the unfrozen mixture, filtering to remove mycelium, and collecting fermentation filtrate; adding absolute ethyl alcohol with the same mass into the fermentation filtrate for alcohol precipitation of polysaccharide to obtain polysaccharide precipitate; collecting polysaccharide precipitates, and repeatedly washing the polysaccharide precipitates with an ethanol solution to obtain washed polysaccharide precipitates; and centrifuging the washed polysaccharide precipitate, collecting the centrifuged polysaccharide precipitate, and redissolving the polysaccharide precipitate in the solvent. According to the technical scheme, the freezing and thawing step is specifically applied to the mycelium-containing schizophyllum commune fermentation mixture, and the colorless schizophyllum commune polysaccharide with excellent transparency is obtained by taking secreted exopolysaccharide as a main target for non-pure mycelium.

The invention discloses a method for preparing schizophyllum commune polysaccharide through high-pressure homogenization and application of the schizophyllum commune polysaccharide, and belongs to the technical field of food and medical treatment. On the basis of a traditional water extraction and alcohol precipitation process, the molecular weight and viscosity of schizophyllum commune fermentation liquor polysaccharide are remarkably reduced through a high-pressure homogenization technology, the schizophyllum commune fermentation liquor polysaccharide is smoother in morphology, and meanwhile a triple-helix structure is maintained; the physical properties of the polysaccharide treated by the method are optimized, and the immunoregulation, anti-apoptosis and anti-oxidative damage activity are also remarkably enhanced. Furthermore, the polysaccharide-selenium nanoparticle compound is prepared from the polysaccharide, sodium selenite and L-ascorbic acid through a mild one-step oxidation-reduction method, the water solubility, biocompatibility and bioavailability of the polysaccharide can be effectively improved through the compound, and the polysaccharide-selenium nanoparticle compound shows more excellent apoptosis resistance and oxidation resistance in a model experiment.

The invention belongs to the technical field of skin care products, and particularly relates to a skin care composition for improving skin elasticity and a preparation method and application thereof. The skin care composition is prepared from the following raw materials in percentage by mass: 0.1 to 0.5 percent of ganoderma sinensis extract, 10 to 20 percent of rice fermentation product filtrate, 1 to 5 percent of ginseng root extract, 1 to 5 percent of peony extract, 0.1 to 1 percent of saussurea involucrata extract, 0.1 to 0.2 percent of pentaerythritol tetra (bis-tert-butyl hydroxy hydrocinnamate) ester, 10 to 20 percent of hydrogenated polyisobutene and the balance of caprylic / caprin. In the preparation process of the rice fermentation product filtrate, the oligomeric schizophyllan and adenosine components are added, and the synergistic effect of the oligomeric schizophyllan and adenosine can effectively improve the content of total flavonoids and total polyphenols in the rice fermentation product filtrate. Furthermore, the content of total flavonoids and total polyphenols in the rice fermentation product filtrate is increased, so that the improvement effect of the skin care product on the skin elasticity can be effectively improved.

The invention belongs to the technical field of fermentation, and relates to a preparation method of schizophyllum commune mycelium fermentation liquor and a product and application of the schizophyllum commune mycelium fermentation liquor, the preparation method comprises the following steps: inoculating schizophyllum commune into a culture medium, and standing and culturing to obtain primary seed liquor; the first-stage seed solution is inoculated into a culture medium and cultured, a second-stage seed solution is obtained, and culture comprises a standing culture stage and a stirring culture stage which are alternately carried out; and inoculating the secondary seed solution into a culture medium, fermenting, carrying out filter pressing on the obtained fermentation liquid, and collecting filtrate, thereby obtaining the product. According to the method, more schizophyllum commune mycelia are obtained by controlling the preparation mode of the seed liquid, the obtaining of schizophyllum commune polysaccharide during fermentation is promoted, the heavy metals possibly existing due to the heavy metal enrichment capacity of macro fungi are reduced by using the schizophyllum commune mycelia for fermentation, the quality of each batch of products is better controlled, the cost is remarkably reduced, and the method is suitable for industrial production. And the damage to the environment is reduced to a certain extent.

The invention provides a low-sensitivity repairing and relieving composition and application thereof. The composition comprises a sea rice extract, a coastal angelica sinensis extract and lycopene-octenyl succinic acid schizophyllan. The sea rice extract, the coastal angelica sinensis extract and the lycopene-octenyl succinic acid schizophyllan are creatively combined, the components are safe, mild and non-irritating, the excellent oxidation resistance is achieved, fibroblast proliferation can be stimulated, a skin barrier is established, and multi-dimensional skin barrier repair is achieved in a synergistic mode.

The invention relates to an acne-removing and repairing composition containing hydrolyzed sponge as well as a preparation method and application of the acne-removing and repairing composition, and belongs to the technical field of cosmetics. According to the present invention, the capryloyl glycine, the hydrolyzed sponge, the o-cymene-5-ol or the quaternary ammonium salt-73 and the schizophyllan are combined, such that the prepared composition has the excellent acne removing effect; meanwhile, the schizophyllan, the ebony seed oil and the sh-pentapeptide-1 are combined for use, so that the prepared composition has the effects of preserving moisture and locking water. The composition finished product prepared by the invention also has a moisturizing effect on the basis of an acne removing effect, so that the phenomenon that the skin barrier is weakened more or less when the components with the acne removing effect take effect is avoided, and further the skin becomes fragile, dry and sensitive; the stable internal environment of the skin is effectively maintained by maintaining the normal moisture content of the skin, the vicious circle of repeated'damage-oil production-acne growth-re-damage 'of the skin is fundamentally avoided, and efficient and deep repair of the skin is effectively realized.

The invention discloses application of polyphenol in sleep improving medicine, and particularly relates to the technical field of medicine, the sleep improving medicine is included, and the sleep improving medicine is a medicine composition containing an oral preparation and an external preparation; the oral preparation contains a polyphenol component, and the polyphenol component is selected from at least one of a purple leaf lettuce extract, tea polyphenol, flavonoids and resveratrol. The polyphenol components in the oral and external preparations form a synergistic effect, the basic sleep-aiding effect is achieved by oral administration, the sleep-aiding effect is enhanced by external application, and the combined effect of the two preparations is far better than that of schizophyllan in single oral and external preparations under the action of a penetration enhancer, so that the transdermal efficiency of the polyphenol components can be remarkably improved; and the action duration is superposed with the plasma concentration peak time of the oral polyphenol, so that the sleep aiding effect can be continuously exerted, a favorable nerve environment is created for good sleep, the positive influence on intestinal flora is realized, and the number of effective flora is increased.

The invention discloses whitening and brightening tone-up cream and a preparation method thereof, and belongs to the technical field of tone-up cream. Comprising a phase A, a phase B, a phase C and a phase D, the phase C comprises whitening and brightening factors, and the whitening and brightening factors comprise a radix paeoniae alba extract, schizophyllan, a saxifraga stolonifera extract and verbascoside; the four active ingredients of the radix paeoniae alba extract, the schizophyllan, the saxifraga stolonifera extract and the verbascoside form a synergistic whitening system, melanin generation is inhibited, free radicals are removed, melanin deposition is reduced, the overall whitening and skin brightening effect is enhanced, and the multiple effects of whitening, skin brightening, health, nourishing and repairing of an existing tone-up cream product are improved.

The invention relates to a schizophyllan scalp-conditioning and anti-dandruff shampoo composition and a preparation method thereof. The schizophyllan scalp-conditioning and anti-dandruff shampoo composition comprises the following components in percentage by mass: 0.1-5% of schizophyllan, 0.1-5% of an anti-dandruff agent, 0.1-5% of an anti-dandruff agent 0.5 to 10% of compound prebiotics; 0.01-3% of a probiotic fermentation product; 0.1-8% of a yeast active component; 8-25% of a composite surfactant system; and the balance of water and pharmaceutically acceptable auxiliary materials. The preparation method comprises the following steps: step 1, pre-mixing the schizophyllan and the compound prebiotics at 40-50 DEG C; step 2, emulsifying a surfactant system and the mixture obtained in the step 1 at a shearing rate of 2000 to 5000 rpm for 15 to 30 min; step 3, cooling to be less than or equal to 35 DEG C, and then adding a probiotic fermentation product and yeast active ingredients; and step 4, adjusting the pH value to 5.5-6.5, and then filling. The technical problems of scalp barrier damage, flora imbalance and functional component inactivation caused by irritant surface activity of traditional shampoo are solved.

The present invention belongs to the technical field of feed additives, and specifically discloses a composite methane inhibitor and a preparation method thereof. The composite methane inhibitor comprises the following raw materials by weight: 16-21 parts of oligomeric schizophyllan, 6-10 parts of atractylodes lactone IV, 3-5 parts of loganin, 1-5 parts of mannose erythritol lipids, and 4-8 parts of modified montmorillonite. Experimental results show that the components of the composite methane inhibitor cooperate with each other to achieve the effect of regulating intestinal flora and reducing methane content. Specifically, atractylodes lactone IV and loganin synergistically inhibit the activity of methanogens, and oligomeric schizophyllan can inhibit the oxidation of unsaturated fatty acids due to its antioxidant activity, reducing side reactions that may promote methane production; and modified montmorillonite has a larger interlayer spacing and specific surface area, and has excellent adsorption, which is conducive to maintaining the activity of components such as oligomeric schizophyllan, thereby further enhancing the inhibitory effect.

The invention relates to a composition with an eye enlarging effect and application of the composition. The composition is prepared from soluble collagen, tocopheryl nicotinate, acetyl hexapeptide-8, hydrolyzed rice protein, acetyl tetrapeptide-5, Arabic gum, rhizobium gum, an arnica extract and schizophyllum commune fermentation product filtrate. By compounding a plurality of plant extracts and polypeptides for use, excellent effects of tightening, lifting, removing pouches and reducing melanin can be realized, and the eye cream has a visual eye enlarging effect and is more young.

The invention relates to an all-natural cosmetic matrix and application thereof. The cosmetic matrix is prepared from schizophyllum commune polysaccharide, squalene, natural lecithin, camellia-seed oil, oat kernel oil, lysozyme and caesalpinia spinosa gum. The invention develops the cosmetic composition from all natural food materials, the seven specific components are compounded for use, the stability of the system can be realized without adding an additional stabilizer, the longer shelf life of the system can be met without adding an additional preservative, and meanwhile, the cosmetic composition is suitable for being used in the fields of cosmetics, cosmetics, cosmetics and the like. The composition also has excellent skin moisturizing and repairing effects, is comfortable in skin feeling, mild and non-irritant to the skin, simple in formula, green, safe and environment-friendly, can be used as a cosmetic matrix for preparing cosmetic products of various dosage forms, and has a wide prospect.

The invention relates to a schizophyllan hydro-optical needle solution and a preparation method thereof, and belongs to the technical field of medical cosmetology. The invention relates to a schizophyllan hydro-globular needle solution, which comprises schizophyllan, and the concentration of the schizophyllan is 5-10 mg / mL. The moisturizing cream not only has a good moisturizing effect, but also can maintain the effect for a long time.

The invention relates to a hair growth moisturizing essence preparation, which is prepared from the following raw materials in percentage by weight: 1 to 15 percent of active composition, 1.3 to 3.0 percent of nutritional supplement, 2 to 6 percent of humectant, 0.1 to 2 percent of vitamin, 1 to 5 percent of antioxidant, 0.1 to 0.5 percent of coolant, 10 to 20 percent of surfactant, 1 to 5 percent of glycerol, 3 to 8 percent of chitosan and the balance of carrier. The active composition is introduced and comprises the hydrolyzed yeast protein, the schizophyllan, the L-arginine, the biotin, the pyrrolidinyl diaminopyrimidine oxide and the hydrolyzed corn protein, so that hair follicle cells in a resting period are quickly reactivated to a growth period, a relatively long hair growth period is maintained, hair regeneration is effectively promoted, scalp health is improved, and hair color is recovered; the hair thickness is increased, and meanwhile, scurf is reduced.

The invention discloses a preparation method of a high-yield, high-moisture-retention and high-antioxidant-activity raw material, which comprises the following steps: 1) preparing a fermentation culture medium: preparing the fermentation culture medium by using 8-12% by mass of edible sugar, 0.3-1% by mass of soybean meal and the balance of deionized water as raw materials; (2) deep liquid fermentation: sterilizing a fermentation culture medium, and sterilely inoculating the prepared schizophyllum commune seed solution to obtain schizophyllum commune polysaccharide fermentation liquor; and 3) polysaccharide extraction: homogenizing the schizophyllum commune polysaccharide fermentation liquor, and extracting schizophyllum commune crude polysaccharide by adopting a traditional alcohol extraction method. Wild schizophyllum commune is utilized, a full-food-grade raw material characterized by soybean meal is selected to prepare a fermentation culture medium, the schizophyllum commune polysaccharide is prepared through high-yield fermentation, and the schizophyllum commune polysaccharide has high moisturizing and high antioxidant activity and is a potential moisturizing and antioxidant skin care product raw material. Compared with traditional schizophyllum commune fermentation, the method has the advantages of being high in yield, high in activity, easy to operate and the like, and has remarkable economic benefits.

The application relates to the field of repair skin care products, in particular to a cream containing multiple ceramides and a preparation method thereof. The cream containing multiple ceramides comprises the following components: a moisturizing agent A, a thickening agent, an antioxidant; ceramides, a dispersing agent; the ceramides comprise at least two of ceramide EOP, ceramide NS / ceramide NG, ceramide AS, ceramide NP and ceramide AP; a pH regulator, a schizophyllan, a filtrate of saccharomycopsis glycerolatium fermentation product, dipotassium glycyrrhizinate, a moisturizing agent B; water; and the preparation method comprises the following steps: mixing raw materials in the A phase with water until uniform to obtain the A phase; uniformly dissolving raw materials in the B phase to obtain the B phase; mixing the B phase with the A phase, stirring until uniform to obtain a mixture; then adding various raw materials in the C phase into the mixture, stirring until uniform to obtain a finished product. The application has the advantages of quickly repairing skin.

The invention provides a contact lens preserving fluid and a preparation method thereof, and belongs to the technical field of contact lenses. The contact lens preserving fluid is prepared from the following components in parts by mass: 1 to 5 parts of Ectoine, 0.3 to 4 parts of schizophyllan, 0.05 to 0.3 part of humectant, 0.3 to 1.2 parts of pH (Potential of Hydrogen) regulator, 0.5 to 1.5 parts of osmotic pressure regulator, 0.1 to 2 parts of chelating agent, 0.1 to 3 parts of surfactant and 90 to 98 parts of water. The preserving fluid disclosed by the invention can be used for solving dry eyes, relieving eye fatigue, improving the lubricating and moisturizing effects, eliminating inflammation, improving the antibacterial ability and improving the wearing comfort of contact lenses; the humectant and Ectoin are combined, so that the contact lens preserving fluid has good hydrophilicity, stability and adhesive force, and the moisturizing effect of the contact lens preserving fluid is prolonged; the schizophyllan has the effects of enhancing immunity, preserving moisture, resisting oxidation and the like.

The invention provides essence with tightening and anti-wrinkle effects and a preparation method thereof, and relates to the technical field of cosmetics. The essence disclosed by the invention is prepared from a protein composition, superoxide dismutase, schizophyllan, aureobasidium pullulans polysaccharide and a plant extract, the protein composition is composed of recombinant collagen and fibronectin. The protein composition and superoxide dismutase form a closed loop for protection and repair, the former supplements collagen and fills wrinkles, and the latter scavenges free radicals and protects collagen from being degraded; the schizophyllan moisturizes and locks water and enhances the skin barrier, and the pullulan wraps the active ingredients, so that the penetration of the corium layer is promoted, and the instant tightness is provided; the plant extract assists in inhibiting collagen degradation and preventing dynamic wrinkles. The essence has the functions of instant tightening modification and long-term anti-aging repair, can be widely applied to tightening anti-wrinkle cosmetics, and provides an efficient solution for the anti-aging field of cosmetics.

The present application relates to a kind of preparation method and application of carboxymethyl schizophyllan, the preparation method includes the following steps: schizophyllum hypha is pretreated to obtain hypha powder, after adding sodium hydroxide to carry out alkalization treatment, low-temperature freezing treatment is carried out.The present application uses schizophyllum fermentation hypha as raw material to prepare carboxymethyl schizophyllan, omits this operation of purification, greatly reduces the complexity of preparation process, and provides convenience for subsequent industrial production.The prepared carboxymethyl schizophyllan has significant moisturizing, repair effect, and can be used in cosmetic and medical field.

The invention relates to the technical field of freeze-drying type anti-aging cosmetics, and discloses a composition for a double-dosage form freeze-drying essence, the double-dosage form freeze-drying essence and a preparation method and application of the double-dosage form freeze-drying essence. The composition contains a freeze-drying preparation mixture and an activation solvent mixture in a mass ratio of 1: (2-3), the freeze-drying preparation mixture contains a first main agent and a first auxiliary agent, and the first main agent contains 3-o-ethyl ascorbic acid, an animal umbilical cord extract, sodium hyaluronate, oligopeptide-1 and a hydrolyzed sheep placenta extract; the activating solvent mixture contains a second main agent and a second auxiliary agent, and the second main agent contains schizophyllacin and decapeptide-4. Through double-dosage-form isolation protection, a stepped freeze-drying process and facial three-dimensional network construction, the double-dosage-form freeze-drying essence provided by the invention has higher active component content, more stable performance and longer facial retention time.

The invention discloses a composition containing schizophyllan and N-acetylneuraminic acid and application of the composition. The mass ratio of the schizophyllan to the N-acetylneuraminic acid is 1: (0.2-8). According to the invention, the schizophyllan and the N-acetylneuraminic acid are compounded and singly used, so that the schizophyllan and the N-acetylneuraminic acid have a better effect of preventing skin cell senescence and show a synergistic anti-aging effect.

The essence composition for improving the hair health is at least prepared from the following raw materials in parts by weight: 0.1 to 5 parts of pyrimidine oxide, 1 to 2 parts of protein hydrolysate, 0.01 to 0.1 part of schizophyllan and 0.1 to 5 parts of hydroxyferriheme. According to the essence composition for improving the hair health, through the synergistic effect of the pyrrolidinyl diaminopyrimidine oxide, the hydrolyzed yeast protein, the hydrolyzed corn protein and the schizophyllan, the health of hair and scalp can be improved, and the essence composition almost has no irritation to the scalp in the using process and does not have the problems of itching, redness and swelling. Diguanidine tetraphosphate extracted from natural extract polar plankton is introduced, so that infiltration of inflammatory cells can be reduced, growth of bacteria and fungi can be controlled, anti-inflammatory and anti-pruritus effects can be effectively achieved, infection can be effectively prevented, and collagen deposition can be increased.

The present invention discloses a schizophyllan polysaccharide having two molecular weights of 1.54×10 7 Da and 1.85×10 4 The components of Da are composed of glucose, mannose, galactose, and fucose, with the molar ratio of glucose, mannose, galactose, and fucose being 86:8:5:1. The schizophyllan is a non-homopolymeric polysaccharide with glucose as its main component, which can promote the proliferation of HaCaT cells and HUVEC cells. At the same time, the schizophyllan can significantly accelerate the healing rate of wounds in mice with full-thickness skin wound models, and has excellent effects in epithelial re-formation, granulation tissue formation, and tissue remodeling. When 4 mg / mL of schizophyllan is used to treat mouse wounds, the healing rate reaches 96.65%.

The invention discloses an anti-aging composition and application thereof, the anti-aging composition comprises a nannochloropsis oculata extract and schizophyllan, or the anti-aging composition comprises the nannochloropsis oculata extract, the schizophyllan and hyaluronic acid substances. According to the invention, the nannochloropsis oculata extract and the schizophyllatin are compounded, and the compounding of the nannochloropsis oculata extract and the schizophyllatin can synergistically improve the generation of collagen and realize the anti-aging effect. According to the invention, the nannochloropsis oculata extract, the schizophyllan and the hyaluronic acid substance are compounded, the addition of the hyaluronic acid substance further improves the effect of promoting the generation of the collagen, and by screening the molecular weight and components of the hyaluronic acid substance, the nannochloropsis oculata extract, the schizophyllan and the hyaluronic acid substance can achieve the effect of synergistically improving the generation of the collagen; and a more prominent anti-aging effect is realized.

The invention relates to the technical field of cosmetic preparations, in particular to a skin repair polypeptide composition which is composed of a signal peptide group A and a synergistic carrier group B, the group A signal peptide group comprises palmitoyl tripeptide-1, palmitoyl pentapeptide-4, palmitoyl heptapeptide-3, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl decapeptide-5, tripeptide-1, hexapeptide-11 and nonapeptide-1; the group A signal peptide group comprises a group B and a group C; the group B synergistic carrier is prepared from medical-grade mussel mucin, schizophyllum commune polysaccharide, an oily component and water. According to the invention, the medical-grade mussel mucin is used as a polypeptide synergistic carrier, so that the transdermal absorption rate of the polypeptide is remarkably improved, the problem of low transdermal absorption rate of the traditional polypeptide is solved, and the active ingredients can better permeate into the deep layer of the skin to play a role.

The invention relates to the technical field of fermentation engineering and medicines, and discloses a method for producing wogonin and hispidulin through synchronous transformation, which comprises the following steps: 1) preparing a fermentation culture medium; and 2) carrying out solid biotransformation. The wild schizophyllum commune is utilized to perform solid transformation on the traditional Chinese medicine scutellaria baicalensis, synchronous transformation production of wogonin and hispidulin is realized, the drug effects of the solid transformation product and schizophyllum commune polysaccharide are synergistically improved, and the solid transformation product can be directly used without extraction. The method is simple to operate and high in conversion efficiency, particularly the hispidulin is converted and synthesized for the first time, and the method has important application prospects and economic benefits in the field of medicines.

The invention relates to the technical field of biological materials and drug delivery, in particular to an injectable schizophyllan gel drug delivery system and a preparation method thereof. Concentrating the water solution containing the schizophyllan to obtain schizophyllan pregel; soaking the schizophyllan pregel in an organic solvent to obtain organic gel; carrying out wet annealing treatment to obtain annealed gel; the annealed gel is soaked in deionized water, and schizophyllan hydrogel is obtained; performing freeze drying on the schizophyllan hydrogel for the first time to obtain dry gel; carrying out drug loading on the dry-state gel through physical soaking to obtain drug-loaded gel; and carrying out second freeze drying on the drug-loaded gel, and enabling the drug-loaded gel to absorb water. The freezing treatment is beneficial to migration and diffusion of drug molecules into pores of the hydrogel, and the accumulated release amount of the drug is larger. The interaction between a schizophyllan hydrogel network structure and drug molecules is enhanced through the second-time freeze drying treatment, so that the drug diffusion rate is reduced, and the slow release effect is achieved.

The invention provides an application of schizophyllan in preparation of a nerve beautifying or emotion skin care product, and the schizophyllan can improve the generation of oxytocin and enorphin, so that the schizophyllan can be used in the nerve beautifying or emotion skin care product. The traditional Chinese medicine composition has the effects of regulating brain waves, increasing the pain threshold value of the skin, reducing external pressure, reducing skin sensitivity, relieving the tension state of the skin and improving the skin quality, and can reduce skin pain and pruritus, reduce external stimulation and pressure on the skin and improve the sensitive skin quality.