Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

22 results about "Schizophyllan" patented technology

Schizophyllan (Sonifilan, SPG) is a neutral extracellular polysaccharide produced by the fungus Schizophyllum commune. Schizophyllan is a β-1,3 beta-glucan with β-1,6 branching. Schizophyllan is also known as sizofiran.

A full-link whitening and freckle-removing liposome and a preparation method thereof

PendingCN122440475AYeast ProteinsCell membrane
The present application relates to the field of cosmetic technology, and more particularly to a full-link whitening and freckle-removing liposome and a preparation method thereof, the liposome comprising the following components: an aqueous phase, a membrane material and an oil phase. In the preparation process, 4-butyl resorcinol, nonapeptide-1, acetylchitosamine and ascorbic acid tetraisopalmitate are combined to form a full-link effect of signal inhibition-synthesis blockage-blocked conversion-metabolic acceleration, and a multi-target whitening and freckle-removing system is constructed. In addition, tranexamic acid, hydrolyzed yeast protein and schizophyllan are combined to synergistically make the finished product have excellent soothing and moisturizing effects. Furthermore, the finished product is prepared into a liposome capable of encapsulating active ingredients, which effectively improves the stability of the active ingredients, prevents their oxidation and inactivation, and the liposome structure is highly similar to the human cell membrane, is easy to penetrate the keratin layer gap, realizes targeted delivery to the deep layer of the epidermis, and makes the active ingredients truly act on the required site.
Owner:GUANGZHOU UNICO TECHNOLOGY DEVELOPMENT CO LTD +1

Skin repair composition, skin repair product and application of skin repair composition and skin repair product

The invention provides a skin repair composition, a skin repair product and application of the skin repair composition and the skin repair product. The skin repair composition comprises the polydeoxyribonucleotide and the salt thereof, the Ectoine or the derivative thereof and the schizophyllan, overcomes the defect of single function of bioactive substances, and has the effects of inhibiting expression of inflammatory factors and accelerating repair of damaged skin pigmentation. The three active ingredients in the skin repair composition are not simply superposed, but generate a synergistic gain effect of '1 + 1 + 1gt, 3', the safety and effectiveness are obviously superior to those in the prior art, and a brand-new and excellent solution is provided for solving the problems of light and moderate acne of teenagers and hyperpigmentation after healing.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

High-transparency schizophyllum commune polysaccharide as well as preparation method and cosmetics thereof

The invention relates to the field of cosmetics, in particular to high-transparency schizophyllum commune polysaccharide, a preparation method thereof and cosmetics. The method comprises the following steps: freezing a schizophyllum commune fermentation mixture containing mycelia under a negative temperature condition to obtain a frozen product; unfreezing the frozen product to obtain an unfrozen mixture; centrifuging the unfrozen mixture, filtering to remove mycelium, and collecting fermentation filtrate; adding absolute ethyl alcohol with the same mass into the fermentation filtrate for alcohol precipitation of polysaccharide to obtain polysaccharide precipitate; collecting polysaccharide precipitates, and repeatedly washing the polysaccharide precipitates with an ethanol solution to obtain washed polysaccharide precipitates; and centrifuging the washed polysaccharide precipitate, collecting the centrifuged polysaccharide precipitate, and redissolving the polysaccharide precipitate in the solvent. According to the technical scheme, the freezing and thawing step is specifically applied to the mycelium-containing schizophyllum commune fermentation mixture, and the colorless schizophyllum commune polysaccharide with excellent transparency is obtained by taking secreted exopolysaccharide as a main target for non-pure mycelium.
Owner:BEST PHARM (GUANGZHOU) CO LTD

Method for preparing schizophyllan through high-pressure homogenization and application of schizophyllan

The invention discloses a method for preparing schizophyllum commune polysaccharide through high-pressure homogenization and application of the schizophyllum commune polysaccharide, and belongs to the technical field of food and medical treatment. On the basis of a traditional water extraction and alcohol precipitation process, the molecular weight and viscosity of schizophyllum commune fermentation liquor polysaccharide are remarkably reduced through a high-pressure homogenization technology, the schizophyllum commune fermentation liquor polysaccharide is smoother in morphology, and meanwhile a triple-helix structure is maintained; the physical properties of the polysaccharide treated by the method are optimized, and the immunoregulation, anti-apoptosis and anti-oxidative damage activity are also remarkably enhanced. Furthermore, the polysaccharide-selenium nanoparticle compound is prepared from the polysaccharide, sodium selenite and L-ascorbic acid through a mild one-step oxidation-reduction method, the water solubility, biocompatibility and bioavailability of the polysaccharide can be effectively improved through the compound, and the polysaccharide-selenium nanoparticle compound shows more excellent apoptosis resistance and oxidation resistance in a model experiment.
Owner:ANHUI UNIV

Skin care composition for improving skin elasticity and preparation method and application thereof

The invention belongs to the technical field of skin care products, and particularly relates to a skin care composition for improving skin elasticity and a preparation method and application thereof. The skin care composition is prepared from the following raw materials in percentage by mass: 0.1 to 0.5 percent of ganoderma sinensis extract, 10 to 20 percent of rice fermentation product filtrate, 1 to 5 percent of ginseng root extract, 1 to 5 percent of peony extract, 0.1 to 1 percent of saussurea involucrata extract, 0.1 to 0.2 percent of pentaerythritol tetra (bis-tert-butyl hydroxy hydrocinnamate) ester, 10 to 20 percent of hydrogenated polyisobutene and the balance of caprylic / caprin. In the preparation process of the rice fermentation product filtrate, the oligomeric schizophyllan and adenosine components are added, and the synergistic effect of the oligomeric schizophyllan and adenosine can effectively improve the content of total flavonoids and total polyphenols in the rice fermentation product filtrate. Furthermore, the content of total flavonoids and total polyphenols in the rice fermentation product filtrate is increased, so that the improvement effect of the skin care product on the skin elasticity can be effectively improved.
Owner:BEIJING NUOSAI INT MEDICAL RES INST +2

Preparation method of schizophyllum commune mycelium fermentation liquor as well as product and application of schizophyllum commune mycelium fermentation liquor

The invention belongs to the technical field of fermentation, and relates to a preparation method of schizophyllum commune mycelium fermentation liquor and a product and application of the schizophyllum commune mycelium fermentation liquor, the preparation method comprises the following steps: inoculating schizophyllum commune into a culture medium, and standing and culturing to obtain primary seed liquor; the first-stage seed solution is inoculated into a culture medium and cultured, a second-stage seed solution is obtained, and culture comprises a standing culture stage and a stirring culture stage which are alternately carried out; and inoculating the secondary seed solution into a culture medium, fermenting, carrying out filter pressing on the obtained fermentation liquid, and collecting filtrate, thereby obtaining the product. According to the method, more schizophyllum commune mycelia are obtained by controlling the preparation mode of the seed liquid, the obtaining of schizophyllum commune polysaccharide during fermentation is promoted, the heavy metals possibly existing due to the heavy metal enrichment capacity of macro fungi are reduced by using the schizophyllum commune mycelia for fermentation, the quality of each batch of products is better controlled, the cost is remarkably reduced, and the method is suitable for industrial production. And the damage to the environment is reduced to a certain extent.
Owner:SHE LOG (GUANGZHOU) BIOTECHNOLOGY CO LTD

Acne-removing and repairing composition containing hydrolyzed sponge as well as preparation method and application of acne-removing and repairing composition

PendingCN121243032ACosmetic preparationsAntipyreticCAPRYLOYL GLYCINEPharmacology
The invention relates to an acne-removing and repairing composition containing hydrolyzed sponge as well as a preparation method and application of the acne-removing and repairing composition, and belongs to the technical field of cosmetics. According to the present invention, the capryloyl glycine, the hydrolyzed sponge, the o-cymene-5-ol or the quaternary ammonium salt-73 and the schizophyllan are combined, such that the prepared composition has the excellent acne removing effect; meanwhile, the schizophyllan, the ebony seed oil and the sh-pentapeptide-1 are combined for use, so that the prepared composition has the effects of preserving moisture and locking water. The composition finished product prepared by the invention also has a moisturizing effect on the basis of an acne removing effect, so that the phenomenon that the skin barrier is weakened more or less when the components with the acne removing effect take effect is avoided, and further the skin becomes fragile, dry and sensitive; the stable internal environment of the skin is effectively maintained by maintaining the normal moisture content of the skin, the vicious circle of repeated'damage-oil production-acne growth-re-damage 'of the skin is fundamentally avoided, and efficient and deep repair of the skin is effectively realized.
Owner:GUANGZHOU NOYASSURE BIOCHEM AND TECH CO LTD

Whitening and brightening tone-up cream and preparation method thereof

The invention discloses whitening and brightening tone-up cream and a preparation method thereof, and belongs to the technical field of tone-up cream. Comprising a phase A, a phase B, a phase C and a phase D, the phase C comprises whitening and brightening factors, and the whitening and brightening factors comprise a radix paeoniae alba extract, schizophyllan, a saxifraga stolonifera extract and verbascoside; the four active ingredients of the radix paeoniae alba extract, the schizophyllan, the saxifraga stolonifera extract and the verbascoside form a synergistic whitening system, melanin generation is inhibited, free radicals are removed, melanin deposition is reduced, the overall whitening and skin brightening effect is enhanced, and the multiple effects of whitening, skin brightening, health, nourishing and repairing of an existing tone-up cream product are improved.
Owner:GUANG ZHOU KA LUO LAI HUA ZHUANG PIN YOU XIAN GONG SI

Schizophyllan shampoo composition capable of conditioning scalp and removing dandruff and preparation method of schizophyllan shampoo composition

The invention relates to a schizophyllan scalp-conditioning and anti-dandruff shampoo composition and a preparation method thereof. The schizophyllan scalp-conditioning and anti-dandruff shampoo composition comprises the following components in percentage by mass: 0.1-5% of schizophyllan, 0.1-5% of an anti-dandruff agent, 0.1-5% of an anti-dandruff agent 0.5 to 10% of compound prebiotics; 0.01-3% of a probiotic fermentation product; 0.1-8% of a yeast active component; 8-25% of a composite surfactant system; and the balance of water and pharmaceutically acceptable auxiliary materials. The preparation method comprises the following steps: step 1, pre-mixing the schizophyllan and the compound prebiotics at 40-50 DEG C; step 2, emulsifying a surfactant system and the mixture obtained in the step 1 at a shearing rate of 2000 to 5000 rpm for 15 to 30 min; step 3, cooling to be less than or equal to 35 DEG C, and then adding a probiotic fermentation product and yeast active ingredients; and step 4, adjusting the pH value to 5.5-6.5, and then filling. The technical problems of scalp barrier damage, flora imbalance and functional component inactivation caused by irritant surface activity of traditional shampoo are solved.
Owner:GUANGDONG BOAO SKIN LIFE ENGINEERING RESEARCH CO LTD

Composition with eye enlarging effect and application thereof

The invention relates to a composition with an eye enlarging effect and application of the composition. The composition is prepared from soluble collagen, tocopheryl nicotinate, acetyl hexapeptide-8, hydrolyzed rice protein, acetyl tetrapeptide-5, Arabic gum, rhizobium gum, an arnica extract and schizophyllum commune fermentation product filtrate. By compounding a plurality of plant extracts and polypeptides for use, excellent effects of tightening, lifting, removing pouches and reducing melanin can be realized, and the eye cream has a visual eye enlarging effect and is more young.
Owner:GUANGDONG MARUBI BIOLOGICAL TECH CO LTD

All-natural cosmetic matrix and application thereof

The invention relates to an all-natural cosmetic matrix and application thereof. The cosmetic matrix is prepared from schizophyllum commune polysaccharide, squalene, natural lecithin, camellia-seed oil, oat kernel oil, lysozyme and caesalpinia spinosa gum. The invention develops the cosmetic composition from all natural food materials, the seven specific components are compounded for use, the stability of the system can be realized without adding an additional stabilizer, the longer shelf life of the system can be met without adding an additional preservative, and meanwhile, the cosmetic composition is suitable for being used in the fields of cosmetics, cosmetics, cosmetics and the like. The composition also has excellent skin moisturizing and repairing effects, is comfortable in skin feeling, mild and non-irritant to the skin, simple in formula, green, safe and environment-friendly, can be used as a cosmetic matrix for preparing cosmetic products of various dosage forms, and has a wide prospect.
Owner:GUANGDONG MARUBI BIOLOGICAL TECH CO LTD

Schizophyllan hydro-optical needle solution and preparation method thereof

PendingCN121622503ACosmetic preparationsToilet preparationsMOISTURIZING CREAMBiochemistry
The invention relates to a schizophyllan hydro-optical needle solution and a preparation method thereof, and belongs to the technical field of medical cosmetology. The invention relates to a schizophyllan hydro-globular needle solution, which comprises schizophyllan, and the concentration of the schizophyllan is 5-10 mg / mL. The moisturizing cream not only has a good moisturizing effect, but also can maintain the effect for a long time.
Owner:GUANGDONG WANMEI BIOTECHNOLOGY CO LTD +1

Hair growth moisturizing essence preparation and preparation and use method thereof

The invention relates to a hair growth moisturizing essence preparation, which is prepared from the following raw materials in percentage by weight: 1 to 15 percent of active composition, 1.3 to 3.0 percent of nutritional supplement, 2 to 6 percent of humectant, 0.1 to 2 percent of vitamin, 1 to 5 percent of antioxidant, 0.1 to 0.5 percent of coolant, 10 to 20 percent of surfactant, 1 to 5 percent of glycerol, 3 to 8 percent of chitosan and the balance of carrier. The active composition is introduced and comprises the hydrolyzed yeast protein, the schizophyllan, the L-arginine, the biotin, the pyrrolidinyl diaminopyrimidine oxide and the hydrolyzed corn protein, so that hair follicle cells in a resting period are quickly reactivated to a growth period, a relatively long hair growth period is maintained, hair regeneration is effectively promoted, scalp health is improved, and hair color is recovered; the hair thickness is increased, and meanwhile, scurf is reduced.
Owner:MINGXING KEPAI BIOTECHNOLOGY (SHANGHAI) CO LTD

A cream containing multiple ceramides and a method for preparing the same

ActiveCN117338647BCosmetic preparationsToilet preparationsSaccharomycopsisMedicine
The application relates to the field of repair skin care products, in particular to a cream containing multiple ceramides and a preparation method thereof. The cream containing multiple ceramides comprises the following components: a moisturizing agent A, a thickening agent, an antioxidant; ceramides, a dispersing agent; the ceramides comprise at least two of ceramide EOP, ceramide NS / ceramide NG, ceramide AS, ceramide NP and ceramide AP; a pH regulator, a schizophyllan, a filtrate of saccharomycopsis glycerolatium fermentation product, dipotassium glycyrrhizinate, a moisturizing agent B; water; and the preparation method comprises the following steps: mixing raw materials in the A phase with water until uniform to obtain the A phase; uniformly dissolving raw materials in the B phase to obtain the B phase; mixing the B phase with the A phase, stirring until uniform to obtain a mixture; then adding various raw materials in the C phase into the mixture, stirring until uniform to obtain a finished product. The application has the advantages of quickly repairing skin.
Owner:广州旭帆生物科技有限公司 +2

Contact lens preserving fluid and preparation method thereof

The invention provides a contact lens preserving fluid and a preparation method thereof, and belongs to the technical field of contact lenses. The contact lens preserving fluid is prepared from the following components in parts by mass: 1 to 5 parts of Ectoine, 0.3 to 4 parts of schizophyllan, 0.05 to 0.3 part of humectant, 0.3 to 1.2 parts of pH (Potential of Hydrogen) regulator, 0.5 to 1.5 parts of osmotic pressure regulator, 0.1 to 2 parts of chelating agent, 0.1 to 3 parts of surfactant and 90 to 98 parts of water. The preserving fluid disclosed by the invention can be used for solving dry eyes, relieving eye fatigue, improving the lubricating and moisturizing effects, eliminating inflammation, improving the antibacterial ability and improving the wearing comfort of contact lenses; the humectant and Ectoin are combined, so that the contact lens preserving fluid has good hydrophilicity, stability and adhesive force, and the moisturizing effect of the contact lens preserving fluid is prolonged; the schizophyllan has the effects of enhancing immunity, preserving moisture, resisting oxidation and the like.
Owner:GANSU KANGSHILI CONTACT LENS CO LTD

Preparation method of carboxymethyl split-pitted polysaccharide and application thereof

ActiveCN120441723BSchizophyllumBiology
The present application relates to a kind of preparation method and application of carboxymethyl schizophyllan, the preparation method includes the following steps: schizophyllum hypha is pretreated to obtain hypha powder, after adding sodium hydroxide to carry out alkalization treatment, low-temperature freezing treatment is carried out.The present application uses schizophyllum fermentation hypha as raw material to prepare carboxymethyl schizophyllan, omits this operation of purification, greatly reduces the complexity of preparation process, and provides convenience for subsequent industrial production.The prepared carboxymethyl schizophyllan has significant moisturizing, repair effect, and can be used in cosmetic and medical field.
Owner:GUANGDONG MARUBI BIOLOGICAL TECH CO LTD

Composition for double-dosage-form freeze-dried essence, double-dosage-form freeze-dried essence and preparation method and application of double-dosage-form freeze-dried essence

The invention relates to the technical field of freeze-drying type anti-aging cosmetics, and discloses a composition for a double-dosage form freeze-drying essence, the double-dosage form freeze-drying essence and a preparation method and application of the double-dosage form freeze-drying essence. The composition contains a freeze-drying preparation mixture and an activation solvent mixture in a mass ratio of 1: (2-3), the freeze-drying preparation mixture contains a first main agent and a first auxiliary agent, and the first main agent contains 3-o-ethyl ascorbic acid, an animal umbilical cord extract, sodium hyaluronate, oligopeptide-1 and a hydrolyzed sheep placenta extract; the activating solvent mixture contains a second main agent and a second auxiliary agent, and the second main agent contains schizophyllacin and decapeptide-4. Through double-dosage-form isolation protection, a stepped freeze-drying process and facial three-dimensional network construction, the double-dosage-form freeze-drying essence provided by the invention has higher active component content, more stable performance and longer facial retention time.
Owner:GUANGZHOU SENYE BIOMEDICAL TECH CO LTD

Composition containing schizophyllan and N-acetylneuraminic acid and application thereof

The invention discloses a composition containing schizophyllan and N-acetylneuraminic acid and application of the composition. The mass ratio of the schizophyllan to the N-acetylneuraminic acid is 1: (0.2-8). According to the invention, the schizophyllan and the N-acetylneuraminic acid are compounded and singly used, so that the schizophyllan and the N-acetylneuraminic acid have a better effect of preventing skin cell senescence and show a synergistic anti-aging effect.
Owner:BLOOMATURE BIOTECHNOLOGY CO LTD

Essence composition for improving hair health and application thereof

The essence composition for improving the hair health is at least prepared from the following raw materials in parts by weight: 0.1 to 5 parts of pyrimidine oxide, 1 to 2 parts of protein hydrolysate, 0.01 to 0.1 part of schizophyllan and 0.1 to 5 parts of hydroxyferriheme. According to the essence composition for improving the hair health, through the synergistic effect of the pyrrolidinyl diaminopyrimidine oxide, the hydrolyzed yeast protein, the hydrolyzed corn protein and the schizophyllan, the health of hair and scalp can be improved, and the essence composition almost has no irritation to the scalp in the using process and does not have the problems of itching, redness and swelling. Diguanidine tetraphosphate extracted from natural extract polar plankton is introduced, so that infiltration of inflammatory cells can be reduced, growth of bacteria and fungi can be controlled, anti-inflammatory and anti-pruritus effects can be effectively achieved, infection can be effectively prevented, and collagen deposition can be increased.
Owner:MINGXING KEPAI BIOTECHNOLOGY (SHANGHAI) CO LTD

Anti-aging composition and application thereof

The invention discloses an anti-aging composition and application thereof, the anti-aging composition comprises a nannochloropsis oculata extract and schizophyllan, or the anti-aging composition comprises the nannochloropsis oculata extract, the schizophyllan and hyaluronic acid substances. According to the invention, the nannochloropsis oculata extract and the schizophyllatin are compounded, and the compounding of the nannochloropsis oculata extract and the schizophyllatin can synergistically improve the generation of collagen and realize the anti-aging effect. According to the invention, the nannochloropsis oculata extract, the schizophyllan and the hyaluronic acid substance are compounded, the addition of the hyaluronic acid substance further improves the effect of promoting the generation of the collagen, and by screening the molecular weight and components of the hyaluronic acid substance, the nannochloropsis oculata extract, the schizophyllan and the hyaluronic acid substance can achieve the effect of synergistically improving the generation of the collagen; and a more prominent anti-aging effect is realized.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD +1

Preparation and application of skin repair polypeptide composition

The invention relates to the technical field of cosmetic preparations, in particular to a skin repair polypeptide composition which is composed of a signal peptide group A and a synergistic carrier group B, the group A signal peptide group comprises palmitoyl tripeptide-1, palmitoyl pentapeptide-4, palmitoyl heptapeptide-3, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl decapeptide-5, tripeptide-1, hexapeptide-11 and nonapeptide-1; the group A signal peptide group comprises a group B and a group C; the group B synergistic carrier is prepared from medical-grade mussel mucin, schizophyllum commune polysaccharide, an oily component and water. According to the invention, the medical-grade mussel mucin is used as a polypeptide synergistic carrier, so that the transdermal absorption rate of the polypeptide is remarkably improved, the problem of low transdermal absorption rate of the traditional polypeptide is solved, and the active ingredients can better permeate into the deep layer of the skin to play a role.
Owner:HANGZHOU CHUANGTIDE BIOTECHNOLOGY CO LTD

Method for producing wogonin and hispidulin through synchronous conversion

The invention relates to the technical field of fermentation engineering and medicines, and discloses a method for producing wogonin and hispidulin through synchronous transformation, which comprises the following steps: 1) preparing a fermentation culture medium; and 2) carrying out solid biotransformation. The wild schizophyllum commune is utilized to perform solid transformation on the traditional Chinese medicine scutellaria baicalensis, synchronous transformation production of wogonin and hispidulin is realized, the drug effects of the solid transformation product and schizophyllum commune polysaccharide are synergistically improved, and the solid transformation product can be directly used without extraction. The method is simple to operate and high in conversion efficiency, particularly the hispidulin is converted and synthesized for the first time, and the method has important application prospects and economic benefits in the field of medicines.
Owner:HUAIYIN TEACHERS COLLEGE