78 results about "Cutaneous infections" patented technology

I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA/UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, "love handles" in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery system.

The present invention relates to compositions and methods of treating warts and other human papilloma virus (HPV) skin infections. The present invention relates to compositions and methods of treating skin cancer.

Disclosed is a disposable absorption article containing the super absorption polymer and the control agent formed by the cyclodextrin and the peculiar smell masking or/and the function substance preventing the skin infection that are wrapped in the empty cavity of the cyclodextrin molecules. The peculiar smell masking or/and the function substance preventing the skin infection are one kind or a plurality of kinds among the hydrophobic compound or/and mixture having the deodorization, aroma, antibacterial action, anti-allergy and cooling functions that are suitable for being wrapped in the empty cavity of the cyclodextrin molecules. In the super absorption polymer and the mixture of the control agent, the weight ratio of the control agent to the mixture is zero point one percent to fifteen percent, the optimized is eight percent to twelve percent, the more optimized is nine percent to eleven percent. And the super absorption polymer and the mixture of the control agent are added with proper dispersant and antibacterial agent having the performance of water-solubility or dispersibility. The invention can effectively and reliably provide the peculiar smell control or/and skin infection preventing functions, and can facilitate the making and can be packaged and staraged by the normal means.

The invention provides lipopeptid which comprises a peptide chain and an aliphatic chain which are connected through peptide bonds, wherein the molecular weight of the lipopeptid is 2848Da, and the lipopeptid is linear, and can obviously introduce the expression of phylaxin, and effectively inhibit staphylococcus aureus infection so as to prevent or reduce skin infection. The invention also discloses a derivative of the lipopeptid and preparation methods and application of the lipopeptid and the derivative of the lipopeptid.

The invention discloses an essential oil composition prepared by performing rectification and compounding processing on the raw materials comprising 4-terpilenol type tea-tree-oil and eucalyptus grandis x e.urophylla essential oil, and provides the formula, a preparation method and the composition content of the essential oil composition; and the composition has antibacterial insecticidal functions. A gas chromatography method is employed to determine the main content. The method is accurate, stable and easy to operate, is adaptable for industrial production demands, and can help to effectively control the quality of the essential oil composition. The essential oil composition has small toxicity, has different levels of inhibition effects on six pathogens comprising staphylococcus aureus, staphylococcus epidermidis, beta hemolytic streptococcus, escherichia coli, pseudomonas aeruginosa and candida albicans which can cause skin infection, and has antibacterial and insecticidal activities. The preparation method is reasonable and stable, short in production period, suitable for industrial production, and good in application prospect.

The present invention relates to a method for preventing infection of the genital mucosa of a mammal by virus, pathogenic bacteria or fungi, comprising topically administering, to the genital mucosa of the mammal, an effective prophylactic amount of a formulation comprising a hydrogel which comprises a microbicidal lipid as an active ingredient, a water gelling agent and a solubilizing agent. The microbicidal lipid is preferably a C6-18 fatty acid or salt thereof, fatty acid monoglycerides, fatty acid esters of monohydric alcohols, fatty alcohols or fatty alcohol monoglycerides ether.

The invention discloses a skin antimicrobial gel recipe and a preparation method thereof. The gel comprises the raw materials of chitosan-iodine, glacial acetic acid, polysorbate-20, glycerin, potassium iodate, chitosan and purified water. The preparation method comprises the following steps of: (1) weighing; (2) adding the glacial acetic acid, the polysorbate-20, the glycerin and the purified water into the chitosan-iodine, mixing uniformly and dissolving completely; (3) dissolving the potassium iodate with the purified water, and adding the dissolved potassium iodate into the mixture to be stirred uniformly; (4) adding the chitosan to stir and dissolve; and (5) adding the purified water to 100% finally, slowly stirring to form the gel, standing and degassing to obtain a skin antimicrobial gel finished product. The skin antimicrobial gel has the advantages of no toxicity, no stimulus, good stability and no tolerance; and the skin antimicrobial gel is suitable for treating and preventing skin and subcutaneous infection and promoting wound healing, such as primary skin infection of impetigo vulgaris, furuncle and the like, secondary skin infection of eczema concurrent infection, trauma concurrent infection and the like as well as tinea manus and pedis, tinea corporis and tinea cruis which are caused by fungal infection.

The invention discloses a compound pearl powder. The compound pearl powder is composed of following raw materials in parts by weight: 10 to 15 parts of borax, 15 to 20 parts of calamitas urinae hominis, 20 to 25 parts of plaster of paris, 25 to 30 parts of pearl powder, 8 to 12 parts of raw alum, 5 to 7 parts of realgar, 20 to 25 parts of powdered steatile, 10 to 15 parts of cinnabar, 5 to 10 parts of mint cream, 4 to 8 parts of persimmon cream, 3 to 6 parts of snake gourd fruit cream, 2 to 5 parts of banana leaves, 3 to 4 parts of sword bean hulls, 1 to 3 parts of babylon weeping willow root-bark, 2 to 3 parts of nidus vespae and 5 to 8 parts of borneol. The traditional Chinese medicine herbs mentioned above are used together to have the functions of clearing away heat and toxic materials, treating cutaneous infection with hemostasis, activating blood circulation to dissipate blood stasis, removing slough and promoting growth of tissue regeneration, the compound pearl powder is suitable for curing diseases such as stomatitis, oral ulcer, mucosal tissue ulcer, erysipelas, disunion of wounds of sore and ulcer, and the like, and the wounds of ulcer can be rapidly and effectively cured by the compound pearl powder. The compound pearl powder has the advantages of short curing process, good curative effects, convenience in taking, no pain, no side effects and no recurrence after cure.

The invention discloses a yolk biological protein liquid and a yolk biological protein skin repair dressing prepared from the yolk biological protein liquid. The yolk biological protein skin repair dressing is prepared from main components as follows: 1%-5% of multiple yolk protein, 0.1%-0.3% of an epidermal growth factor and the balance of a hyaluronic acid solution, wherein the multiple yolk protein is an egg yolk antibody obtained by performing injection immunity on healthy hens, taking eggs laid by the hens and performing separation and purification with one or more pathogens capable of causing skin infection used as immunogen. The multiple yolk protein can inactivate various pathogens causing skin infection in a targeted manner, promote operation wound recovery and effectively prevent bacterial infection and causes no irritation to human bodies, and the added epidermal growth factor can repair wounds, promote epidermal wound surfaces to restore quickly, moisten skin and eliminate winkles and scars, has better biocompatibility with the multiple yolk protein, causes no dependence and drug resistance, has no allergy and is safe and efficient.

The invention discloses a preparation method and an application of a boric acid functionalized graphene material with targeted photo-thermal sterilization performance, and the preparation method comprises the following steps: step 1, uniformly mixing carboxylatedgraphene, EDC, NHS and deionized water, and stirring at room temperature; step 2, adding 3-aminopyridine into the mixed liquor, and stirring at room temperature; step 3, performing centrifugal treatment, and washing with deionized water; step 4, resuspending the product obtained in step 3 with DMF, and adding 3-phenylboronic acid, andstirring under oil bath conditions; step 5, carrying out centrifugal treatment and washing by using deionized water to obtain the boric acid functionalized graphene material with the targeted photo-thermal sterilization performance. The preparation method has the advantages of high-efficiency targeting bacteria and capability of photothermal killing bacteria, good biocompatibility and simple preparation method; the preparation method can effectively treat skin wound surface infection of multiple drug-resistant Gram-negative bacilli and promote healing of skin infection wound surface.

The invention discloses a foam type lavender antibacterial lotion. The foam type lavender antibacterial lotion is prepared from the following raw materials in parts by weight of 0.2 to 1 part of lavender, 0.2 to 1 part of cortex phellodendri, 0.1 to 0.5 part of radix sophorae flavescentis, 0.1 to 0.5 part of fructus cnidii, 0.02 to 0.1 part of borneol, 0.02 to 0.1 part of menthol, 0.2 to 1 part ofchlorhexidine acetate, 5 to 25 parts of propylene glycol, 20 to 100 parts of glycerol, 1 to 5 parts of sodium dodecyl sulfate, 0.4 to 2 parts of polysorbate and 0.25 to 2 parts of an aromatic agent.The foam type lavender antibacterial lotion is in a foam state after being extruded, rich foam can be generated through light kneading, compared with liquid lotion, the action of kneading and foamingis omitted, and more labor is saved during flushing. The faintly acid formula maintains the resistance of the faintly acid environment of the private part, and can effectively inhibit private part infection and skin infection caused by pathogenic bacteria such as candida albicans, staphylococcus aureus and the like.

The present invention relates to the topical compositions comprising clindamycin phosphate, salicylic acid and tea tree oil; to the preparation methods thereof; and to the use thereof in the treatment of skin infections and acne vulgaris accompanied by inflammatory lesions.

The invention provides a linezolid crystal form B. In a powder X-ray diffraction pattern of the crystal form, characteristic absorption peaks exist in the 9.43-degree position, the 11.29-degree position, the 13.27-degree position, the 14.13-degree position, the 15.55-degree position, the 16.69-degree position, the 19.04-degree position, the 21.92-degree position and the 22.35-degree position of the diffraction angle 2theta (+/-0.2 degree). The crystal form has the advantages of being small in grain diameter, good in dissolution rate and the like. The invention further provides a preparation method of the crystal form, a medicine composition containing the crystal form in the treatment effective dose, and an application of the medicine composition in treating skin infection caused by various germs.

The invention discloses application of tea polyphenol and derivatives thereof in prevention of schistosoma japonicum katsurada infection, and belongs to the field of medical technology and preventive medicine. The tea polyphenol and derivatives thereof can be used for preventing schistosoma japonicum katsurada infection, in particular for destruction of epigallocatechin-3-gallate to the structure of cercaria in affected water, weakening the skin penetrating function of cercaria, and preventing per-cutaneous infection of schistosoma japonicum katsurada.

The invention discloses a traditional Chinese medicine preparation for treating pain and skin infection ulceration and a preparation method thereof, and belongs to the field of medicinal liquor, the traditional Chinese medicine preparation is prepared by secondary soaking of a traditional Chinese medicine composition in 40-60-degree liquor, the weight ratio of the 40-60-degree liquor to the traditional Chinese medicine composition during primary soaking is 5: 1, and the weight ratio of the 40-60-degree liquor to the traditional Chinese medicine composition during secondary soaking is 2: 1; the traditional Chinese medicine composition is prepared from the following raw materials: thymus mongolicus, flemingia philippinensis, cudrania cochinchinensis, polygala fallax hemsl, fructus gardeniae, elecampane, agastache rugosus, agilawood, frankincense, pepper, pseudo-ginseng, garden balsam stem, lignum dalbergiae odoriferae, sandalwood, hematoxylon, rhizoma sparganii, myrrh, radix paeoniae rubra, radix dipsaci, safflower, borneol, mint ice, and asiatic toddalia root. The preparation method is simple, pure traditional Chinese medicines are brewed, and side effects are avoided; the traditional Chinese medicine preparation is convenient to use, can be sprayed, wiped and applied, can be used for cleaning and disinfecting wounds, and has the effects of promoting tissue regeneration and burying mouths while resisting bacteria and diminishing inflammation.

The invention discloses a loop stoma airbag-type bracket. The loop stoma airbag-type bracket comprises a rubber tube which is a hallow structure; the left end of the rubber tube is coated with an integrally molded left airbag; the right end of the rubber tube is coated with an integrally molded right airbag; gas holes are formed, inside the left airbag and the right airbag, on the rubber tube so as to realize entering of gas into the airbags; and inflatable gas nozzles are arranged at the end parts of the rubber tube. The loop stoma airbag-type bracket is simple in structure, convenient to operate, free of adoption of a stitching method, and capable of effectively reducing skin infection rate of stoma. A support structure of the loop stoma airbag-type bracket is capable of preventing sliding of the rubber tube, so that intestinal retraction can be truely avoided so as to promote recovery of a patients' intestinal peristalsis and defecation; and moreover, the two ends of the rubber tubeof the loop stoma airbag-type bracket are both inflated airbags, so that the effect of limiting can be achieved after inflation of the airbags so as to prevent falling of the rubber tube. In addition, the loop stoma airbag-type bracket is light in structure as a whole, and is capable of reducing friction between loop stoma and the colon as well as damages caused thereby; and moreover, the rubbertube and the airbags contact with the loop stoma and the intestinal canal are capable of ensuring comfort feeling.

The invention provides an antibacterial peptide composition. The amino acid sequence of the antibacterial peptide is KWKSFLKTFaAbKTVLHTALKAISS, and substitution sites of a and b are selected from any amino acids as follows: L-leucine, D-leucine, L-valine, D-valine, L-alanine, D-alanine, glycine, L-serine, D-serine, L-lysine and D-lysine. The composition comprises at least one stabilizer, antibacterial peptide and a buffer system (preferably disodium hydrogen phosphate and citric acid), and the pH value of the composition is 3.5-5.5. The antibacterial peptide composition is a broad-spectrum anti-infection drug for local external use, is suitable for various primary skin infections caused by pathogenic bacteria, especially drug-resistant bacteria, and secondary skin infections such as eczema combined infection and ulcer combined infection, including stubborn infectious diseases such as diabetic foot, burn wound infection and bedsore infection, and has a wide application prospect.

The invention discloses a niclosamide injection and preparation and application thereof. The preparation comprises the following steps of: weighing 2g of niclosamide, adding 0.5-8g of a solubilizer, uniformly mixing, adding 50-75ml of a solvent, stirring to dissolve, adding a buffer solution after full dissolution, uniformly mixing, and adding water to a specified volume. The injection is clear and transparent, the pH is stable, the Minimal Inhibitory Concentrations (MIC) of staphylococcus aureus sensitive bacteria and oxygenated-resistant penicillin staphylococcus aureus are respectively 0.06 microgram/ml and 0.125 microgram/ml, and after a staphylococcus aureus mouse skin infection model is established, subcutaneous injection of 5mg/kg. bw, 10mg/kg. bw and 20mg/kg. bw respectively shows that the mouse skin infection can be well prevented and treated by an administration group, and the administration group has no significant difference from a control group ciprofloxacin.

The invention discloses a preparation method for environmentally-friendly antibacterial paper for daily use. The preparation method comprises the following steps: preparation of materials; pulping andmixing of the materials; preparation of a primary product; and packaging of a finished product. According to the invention, waste bamboo leaves are fully utilized, so the environmental protection requirement is met; meanwhile, through combination of broadleaf wood and coniferous wood, the beating degree is improved, and the length of the fiber is also ensured at the same time; by adoption of a main body material composed of the waste bamboo leaves, the broadleaf wood and the coniferous wood, the overall raw material is more excellent, and the purposes of energy conservation and emission reduction are met; by adoption of a bactericide composed of natural traditional Chinese herbal medicine extracts, the disinfection function of paper is realized, wherein lygodium japonicum and semen plantaginis have good sterilization effect on urinary tract skin infection, so use is safer; by adoption of a toughening agent, the toughness of the paper is improved; by adoption of a deodorant composed ofnatural substances, the experience of using the paper is improved; and the environmentally-friendly antibacterial paper provided by the invention is free of addition of artificial additives, is saferand healthier, and does not generate obvious adverse effects on environmental products.